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Ian Huscroft

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TOP 3
Ian T Huscroft; Emma J Carlson; Gary G Chicchi; Marc M Kurtz; Clare London; Piotr Raubo; Alan Wheeldon; Janusz J Kulagowski
1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.
Piotr Raubo; Margaret S Beer; Peter A Hunt; Ian T Huscroft; Clare London; Josephine A Stanton; Janusz J Kulagowski
Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.
Christopher G Thomson; Karen Duncan; Stephen R Fletcher; Ian T Huscroft; Gopalan V Pillai; Piotr Raubo; Alison J Smith; Darren Stead
Sarcosine based indandione hGlyT1 inhibitors.

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2006: Ian T Huscroft; Emma J Carlson; Gary G Chicchi; Marc M Kurtz; Clare London; Piotr Raubo; Alan Wheeldon; Janusz J Kulagowski
1-Phenyl-8-azabicyclo[3.2.1]octane ethers: a novel series of neurokinin (NK1) antagonists.
Bioorganic & medicinal chemistry letters 2006;16(7):2008-12.
2006: Piotr Raubo; Margaret S Beer; Peter A Hunt; Ian T Huscroft; Clare London; Josephine A Stanton; Janusz J Kulagowski
Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.
Bioorganic & medicinal chemistry letters 2006;16(5):1255-8.
2006: Christopher G Thomson; Karen Duncan; Stephen R Fletcher; Ian T Huscroft; Gopalan V Pillai; Piotr Raubo; Alison J Smith; Darren Stead
Sarcosine based indandione hGlyT1 inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(5):1388-91.
2005: Martin R Guscott; Linda J Bristow; Karen L Hadingham; Thomas W Rosahl; Margaret S Beer; Josephine A Stanton; Frances A Bromidge; Andrew P Owens; Ian T Huscroft; Janice Myers; Nadia M J Rupniak; Smita Patel; Paul J Whiting; Peter H Hutson; Kevin C F Fone; S M Biello; Janusz J Kulagowski; George McAllister
Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression.
Neuropharmacology 2005;48(4):492-502.
2000: Fraser Murray; J Kennedy; Peter H Hutson; J Elliot; Ian T Huscroft; K Mohnen; Michael G N Russell; Sarah Grimwood
Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.
European journal of pharmacology 2000;397(2-3):263-70.
1998: GI Stevenson; Ian T Huscroft; Angus M MacLeod; Christopher J Swain; Margaret A Cascieri; Gary G Chicchi; M I Graham; Timothy Harrison; Fintan J Kelleher; Marc M Kurtz; Tammy Ladduwahetty; Kevin J Merchant; Joseph M Metzger; D Euan MacIntyre; Sharon Sadowski; Bindi Sohal; Andrew P Owens
4,4-Disubstituted piperidine high-affinity NK1 antagonists: structure-activity relationships and in vivo activity.
Journal of medicinal chemistry 1998;41(23):4623-35.
1998: Jason M Elliott; Howard B Broughton; Margaret A Cascieri; Gary G Chicchi; Ian T Huscroft; Marc M Kurtz; Angus M MacLeod; Sharon Sadowski; GI Stevenson
Serine derived NK1 antagonists. 2: A pharmacophore model for arylsulfonamide binding.
Bioorganic & medicinal chemistry letters 1998;8(14):1851-6.
1997: Nadia M J Rupniak; F David Tattersall; Angela R Williams; Wayne Rycroft; Emma J Carlson; Margaret A Cascieri; Sharon Sadowski; E Ber; Jeffrey J Hale; Sander G Mills; Malcolm MacCoss; Eileen M Seward; Ian T Huscroft; S Owen; Christopher J Swain; Raymond G Hill; Richard Hargreaves
In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.
European journal of pharmacology 1997;326(2-3):201-9.
1995: GI Stevenson; Angus M MacLeod; Ian T Huscroft; Margaret A Cascieri; Sharon Sadowski; R Baker
4,4-Disubstituted piperidines: a new class of NK1 antagonist.
Journal of medicinal chemistry 1995;38(8):1264-6.