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Zuzana Husková

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Zuzana Honetschlägerová; Zuzana Husková; Sung Hee Hwang; John D Imig; Kento Kitada; Libor Kopkan; Herbert kramer; Petr Kujal; Akira Nishiyama; Alexandra Sporková; Šárka Varcabová; Zdena Vernerová; Marcela Bürgelová; Bruce D Hammock; Ludek Cervenka
Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Jan Neckář; Ivan Netuka; Bohuslav Ošťádal; František Papoušek; Bruce D Hammock; Zuzana Husková; Sung Hee Hwang; John D Imig; František Kolář; Libor Kopkan; Herbert J Kramer; Jiří Malý; Ludek Cervenka
Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Libor Kopkan; Herbert kramer; Petr Kujal; Alexandra Sporková; Hsing-Ju Tsai; Zdena Vernerová; Alžběta Vojtíšková; Marcela Bürgelová; Bruce D Hammock; Zuzana Honetschlägerová; Zuzana Husková; Sung Hee Hwang; John D Imig; Šárka Varcabová; Ludek Cervenka
Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.

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All Publications

2013: Zuzana Honetschlägerová; Zuzana Husková; Sung Hee Hwang; John D Imig; Kento Kitada; Libor Kopkan; Herbert kramer; Petr Kujal; Akira Nishiyama; Alexandra Sporková; Šárka Varcabová; Zdena Vernerová; Marcela Bürgelová; Bruce D Hammock; Ludek Cervenka
Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Journal of hypertension 2013;31(2):321-32.
2012: Jan Neckář; Ivan Netuka; Bohuslav Ošťádal; František Papoušek; Bruce D Hammock; Zuzana Husková; Sung Hee Hwang; John D Imig; František Kolář; Libor Kopkan; Herbert J Kramer; Jiří Malý; Ludek Cervenka
Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Clinical science (London, England : 1979) 2012;122(11):513-25.
2012: Libor Kopkan; Herbert kramer; Petr Kujal; Alexandra Sporková; Hsing-Ju Tsai; Zdena Vernerová; Alžběta Vojtíšková; Marcela Bürgelová; Bruce D Hammock; Zuzana Honetschlägerová; Zuzana Husková; Sung Hee Hwang; John D Imig; Šárka Varcabová; Ludek Cervenka
Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.
Kidney & blood pressure research 2012;35(6):595-607.
2012: Ivana Vaněčková; Zdeňka Vaňourková; Zdena Vernerová; Vera Certíková-Chábová; Zuzana Husková; Herbert kramer; Petr Kujal; Petra Skaroupková; Vladimír Tesař; Ludek Cervenka
Effects of combined endothelin A receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats.
Kidney & blood pressure research 2012;35(5):382-92.
2011: Zuzana Honetschlägerová; Zuzana Husková; Sung H Hwang; John D Imig; Libor Kopkan; Herbert J Kramer; Petr Kujal; Alexandra Sporková; Vladimír Tesař; Zdena Vernerová; Vera Certíková Chábová; Bruce D Hammock; Ludek Cervenka
Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.
Journal of hypertension 2011;29(8):1590-601.
2011: Ivana Vaněčková; Zuzana Husková; Zdeňka Vaňourková; Ludek Cervenka
Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats.
Kidney & blood pressure research 2011;34(1):46-52.
2010: Petr Kujal; Věra Čertíková Chábová; Zdena Vernerová; Agnieszka Walkowska; Elzbieta Kompanowska-Jezierska; Janusz Sadowski; Zdeňka Vaňourková; Zuzana Husková; Martin Opočenský; Petra Skaroupková; Stanislava Schejbalová; Herbert J Kramer; Dan Rakušan; Jan Malý; Ivan Netuka; Ivana Vaněčková; Libor Kopkan; Ludek Cervenka
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Clinical and experimental pharmacology & physiology 2010;37(12):1159-69.
2010: Dan Rakusan; Petr Kujal; Herbert kramer; Zuzana Husková; Zdenka Vanourková; Zdena Vernerová; Iveta Mrázová; Monika Thumová; Ludek Cervenka; Ivana Vanecková
Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
American journal of physiology. Renal physiology 2010;299(4):F758-66.
2010: Libor Kopkan; Arthur Hess; Zuzana Husková; Ludek Cervenka; L Gabriel Navar; Dewan S A Majid
High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity.
American journal of physiology. Renal physiology 2010;299(3):F656-63.
2010: Zuzana Husková; Zdenka Vanourková; Michaela Erbanová; Monika Thumová; Martin Opocenský; John J Mullins; Herbert kramer; Marcela Bürgelová; Ludek Cervenka
Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats.
Journal of hypertension 2010;28(3):495-509.
2009: Libor Kopkan; Zuzana Husková; Zdenka Vanourková; Monika Thumová; Petra Skaroupková; Jan Malý; Herbert kramer; Petr Dvorák; Ludek Cervenka
Reduction of oxidative stress does not attenuate the development of angiotensin II-dependent hypertension in Ren-2 transgenic rats.
Vascular pharmacology 2009;51(2-3):175-81.
2009: Zdenka Vanourková; Herbert kramer; Michaela Erbanová; Angela Bäcker; Ludek Cervenka; Zuzana Husková; Vera Certíková Chábová; Vladimír Tesar; Petr Dvorák; Jan Malý; Ivana Vanecková
Endothelin receptor blockade does not affect blood pressure or angiotensin II levels in CYP1A1-Ren-2 transgenic rats with acutely induced hypertension.
Vascular pharmacology 2009;50(5-6):194-9.
2009: Michaela Erbanová; Monika Thumová; Zuzana Husková; Ivana Vanecková; Zdenka Vanourková; John J Mullins; Herbert kramer; Marcela Bürgelová; Dan Rakusan; Ludek Cervenka
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
Journal of hypertension 2009;27(3):575-86.
2008: Ludek Cervenka; Ivana Vanecková; Zuzana Husková; Zdenka Vanourková; Michaela Erbanová; Monika Thumová; Petra Skaroupková; Martin Opocenský; Jan Malý; Vera Certíková Chábová; Vladimír Tesar; Marcela Bürgelová; Ondrej Viklický; Vladimír Teplan; Michal Zelízko; Herbert kramer; L Gabriel Navar
Pivotal role of angiotensin II receptor subtype 1A in the development of two-kidney, one-clip hypertension: study in angiotensin II receptor subtype 1A knockout mice.
Journal of hypertension 2008;26(7):1379-89.
2008: Zdena Vernerová; Herbert kramer; Angela Bäcker; Ludek Cervenka; Martin Opocenský; Zuzana Husková; Zdenka Vanourková; Václav Eis; Vera Certíková Chábová; Vladimír Tesar; Jan Malý; Ivana Vanecková
Late-onset endothelin receptor blockade in hypertensive heterozygous REN-2 transgenic rats.
Vascular pharmacology 2008;48(4-6):165-73.
2007: Libor Kopkan; Zuzana Husková; Zdenka Vanourková; Monika Thumová; Petra Skaroupková; Ludek Cervenka; Dewan S A Majid
Superoxide and its interaction with nitric oxide modulates renal function in prehypertensive Ren-2 transgenic rats.
Journal of hypertension 2007;25(11):2257-65.
2007: Vera Certíková Chábová; Herbert kramer; Ivana Vanecková; Zdena Vernerová; Václav Eis; Vladimír Tesar; Petra Skaroupková; Monika Thumová; Stanislava Schejbalová; Zuzana Husková; Zdenka Vanourková; Alexander Kolský; John D Imig; Ludek Cervenka
Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Vascular pharmacology 2007;47(2-3):145-59.
2007: Ivana Vanecková; Libor Kopkan; Zuzana Husková; Zdenka Vanourková; Stanislava Schejbalová; Ludek Cervenka; Herbert kramer
AT1 receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats.
Vascular pharmacology 2007;47(1):63-7.
2007: Zuzana Husková; Herbert Kramer; Zdenka Vanourková; Monika Thumová; Jan Malý; Martin Opocenský; Petra Skaroupková; Alexander Kolský; Zdena Vernerová; Ludek Cervenka
Effects of dietary salt load and salt depletion on the course of hypertension and angiotensin II levels in male and female heterozygous Ren-2 transgenic rats.
Kidney & blood pressure research 2007;30(1):45-55.
2007: Ivana Vanecková; Libor Kopkan; Zuzana Husková; Zdenka Vanourková; Stanislava Schejbalová; Ludek Cervenka; Herbert kramer
Long-term prevention of hypertension and end-organ damage in Ren-2 transgenic rats is achieved only with persistent but not transient AT1 receptor blockade.
Kidney & blood pressure research 2007;30(1):38-44.
2006: Zdenka Vanourková; Herbert kramer; Zuzana Husková; Ivana Vanecková; Martin Opocenský; Vera Certíková Chábová; Vladimír Tesar; Petra Skaroupková; Monika Thumová; Michaela Dohnalová; John J Mullins; Ludek Cervenka
AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension.
Journal of hypertension 2006;24(12):2465-72.
2006: Zuzana Husková; Herbert kramer; Zdenka Vanourková; Ludek Cervenka
Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic rats.
Journal of hypertension 2006;24(3):517-27.
2006: Zuzana Husková; Ivana Vanecková; Ludek Cervenka
[The renin-angiotensin system].
Ceskoslovenská fysiologie / Ústrední ústav biologický 2006;55(4):138-47.
2006: Zuzana Husková; Herbert kramer; Monika Thumová; Zdenka Vanourková; Marcela Bürgelová; Vladimír Teplan; Jan Malý; Ludek Cervenka
Effects of anesthesia on plasma and kidney ANG II levels in normotensive and ANG II-dependent hypertensive rats.
Kidney & blood pressure research 2006;29(2):74-83.
2005: Libor Kopkan; Herbert kramer; Zuzana Husková; Zdenka Vanourková; Petra Skaroupková; Monika Thurmová; Ludek Cervenka
The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats.
Journal of hypertension 2005;23(8):1531-9.
2004: Libor Kopkan; Herbert kramer; Zuzana Husková; Zdenka Vanourková; Angela Bäcker; Michael Bader; Detlev Ganten; Ludek Cervenka
Plasma and kidney angiotensin II levels and renal functional responses to AT(1) receptor blockade in hypertensive Ren-2 transgenic rats.
Journal of hypertension 2004;22(4):819-25.
2004: Ivana Vanecková; Monika Cahová; Herbert kramer; Zuzana Husková; Petra Skaroupková; Radko Komers; Michael Bader; Detlev Ganten; Ludek Cervenka
Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous ren-2-transgenic rats on normal or low sodium intake.
Kidney & blood pressure research 2004;27(4):203-10.