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Clyde Hutchison

Research Profile

Chemicals & Drugs

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Cloning, Molecular

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Genes & Molecular Sequences

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Daniel G Gibson; John I Glass; carole lartigue; Vladimir N Noskov; Ray-Yuan Chuang; Mikkel A Algire; Gwynedd A Benders; Michael G Montague; Li Ma; Monzia M Moodie; Chuck Merryman; Sanjay Vashee; Radha Krishnakumar; Nacyra Assad-Garcia; Cynthia Andrews-Pfannkoch; Evgeniya A Denisova; Lei Young; Zhi-Qing Qi; Thomas H Segall-Shapiro; Christopher H Calvey; Prashanth P Parmar; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
Creation of a bacterial cell controlled by a chemically synthesized genome.
Gwynedd A Benders; Vladimir N Noskov; Evgeniya A Denisova; Carole Lartigue; Daniel G Gibson; Nacyra Assad-Garcia; Ray-Yuan Chuang; William Carrera; Monzia Moodie; Mikkel A Algire; Quang Phan; Nina Alperovich; Sanjay Vashee; Chuck Merryman; J Craig Venter; Hamilton O Smith; John I Glass; Clyde A Hutchison
Cloning whole bacterial genomes in yeast.
carole lartigue; Sanjay Vashee; Mikkel A Algire; Ray-Yuan Chuang; Gwynedd A Benders; Li Ma; Vladimir N Noskov; Evgeniya A Denisova; Daniel G Gibson; Nacyra Assad-Garcia; Nina Alperovich; David W Thomas; Chuck Merryman; Clyde A Hutchison; Hamilton O Smith; J Craig Venter; John I Glass
Creating bacterial strains from genomes that have been cloned and engineered in yeast.

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All Publications

2010: Daniel G Gibson; John I Glass; carole lartigue; Vladimir N Noskov; Ray-Yuan Chuang; Mikkel A Algire; Gwynedd A Benders; Michael G Montague; Li Ma; Monzia M Moodie; Chuck Merryman; Sanjay Vashee; Radha Krishnakumar; Nacyra Assad-Garcia; Cynthia Andrews-Pfannkoch; Evgeniya A Denisova; Lei Young; Zhi-Qing Qi; Thomas H Segall-Shapiro; Christopher H Calvey; Prashanth P Parmar; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
Creation of a bacterial cell controlled by a chemically synthesized genome.
Science (New York, N.Y.) 2010;329(5987):52-6.
2010: Gwynedd A Benders; Vladimir N Noskov; Evgeniya A Denisova; Carole Lartigue; Daniel G Gibson; Nacyra Assad-Garcia; Ray-Yuan Chuang; William Carrera; Monzia Moodie; Mikkel A Algire; Quang Phan; Nina Alperovich; Sanjay Vashee; Chuck Merryman; J Craig Venter; Hamilton O Smith; John I Glass; Clyde A Hutchison
Cloning whole bacterial genomes in yeast.
Nucleic acids research 2010;38(8):2558-69.
2009: carole lartigue; Sanjay Vashee; Mikkel A Algire; Ray-Yuan Chuang; Gwynedd A Benders; Li Ma; Vladimir N Noskov; Evgeniya A Denisova; Daniel G Gibson; Nacyra Assad-Garcia; Nina Alperovich; David W Thomas; Chuck Merryman; Clyde A Hutchison; Hamilton O Smith; J Craig Venter; John I Glass
Creating bacterial strains from genomes that have been cloned and engineered in yeast.
Science (New York, N.Y.) 2009;325(5948):1693-6.
2009: Daniel G Gibson; Lei Young; Ray-Yuan Chuang; J Craig Venter; Clyde A Hutchison; Hamilton O Smith
Enzymatic assembly of DNA molecules up to several hundred kilobases.
Nature methods 2009;6(5):343-5.
2009: John I Glass; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
A systems biology tour de force for a near-minimal bacterium.
Molecular systems biology 2009;5():330.
2008: Daniel G Gibson; Gwynedd A Benders; Kevin C Axelrod; Jayshree Zaveri; Mikkel A Algire; Monzia Moodie; Michael G Montague; J Craig Venter; Hamilton O Smith; Clyde A Hutchison
One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(51):20404-9.
2008: Daniel G Gibson; Gwynedd A Benders; Cynthia Andrews-Pfannkoch; Evgeniya A Denisova; Holly Baden-Tillson; Jayshree Zaveri; Timothy Stockwell; Anushka Brownley; David W Thomas; Mikkel A Algire; Chuck Merryman; Lei Young; Vladimir N Noskov; John I Glass; J Craig Venter; Clyde A Hutchison; Hamilton O Smith
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.
Science (New York, N.Y.) 2008;319(5867):1215-20.
2007: carole lartigue; John I Glass; Nina Alperovich; Rembert Pieper; Prashanth P Parmar; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
Genome transplantation in bacteria: changing one species to another.
Science (New York, N.Y.) 2007;317(5838):632-8.
2007: Clyde A Hutchison
DNA sequencing: bench to bedside and beyond.
Nucleic acids research 2007;35(18):6227-37.
2007: Hsun-Cheng Su; Clyde A Hutchison; Morgan C Giddings
Mapping phosphoproteins in Mycoplasma genitalium and Mycoplasma pneumoniae.
BMC microbiology 2007;7():63.
2006: Clyde A Hutchison; J Craig Venter
Single-cell genomics.
Nature biotechnology 2006;24(6):657-8.
2006: John I Glass; Nacyra Assad-Garcia; Nina Alperovich; Shibu Yooseph; Matthew R Lewis; Mahir Maruf; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
Essential genes of a minimal bacterium.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(2):425-30.
2006: Bradford C Powell; Clyde A Hutchison
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs.
BMC bioinformatics 2006;7():31.
2005: Clyde A Hutchison; Hamilton O Smith; Cynthia Pfannkoch; J Craig Venter
Cell-free cloning using phi29 DNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(48):17332-6.
2005: Gwynedd A Benders; Bradford C Powell; Clyde A Hutchison
Transcriptional analysis of the conserved ftsZ gene cluster in Mycoplasma genitalium and Mycoplasma pneumoniae.
Journal of bacteriology 2005;187(13):4542-51.
2003: Hamilton O Smith; Clyde A Hutchison; Cynthia Pfannkoch; J Craig Venter
Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15440-5.
2001: M L Mears; Clyde A Hutchison
The evolution of modern lineages of mouse L1 elements.
Journal of molecular evolution 2001;52(1):51-62.
2000: J A Wrobel; M J Conrad; Esa Bloedon; Ronald Swanstrom; Clyde A Hutchison
Analysis of HIV type 1 reverse transcriptase: comparing sequences of viral isolates with mutational data.
AIDS research and human retroviruses 2000;16(18):2049-54.
2000: M G Montague; Clyde A Hutchison
Gene content phylogeny of herpesviruses.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5334-9.
1999: Clyde A Hutchison; Scott N Peterson; Steven R Gill; R T Cline; Owen R White; Claire M Fraser-Liggett; Hamilton O Smith; J Craig Venter
Global transposon mutagenesis and a minimal Mycoplasma genome.
Science (New York, N.Y.) 1999;286(5447):2165-9.
1999: Masaru Tomita; K Hashimoto; Kouichi Takahashi; T S Shimizu; Y Matsuzaki; Fumihiko Miyoshi; K Saito; S Tanida; Katsuyuki Yugi; J C Venter; Clyde A Hutchison
E-CELL: software environment for whole-cell simulation.
Bioinformatics (Oxford, England) 1999;15(1):72-84.
1998: T O Tollefsbol; Clyde A Hutchison
Analysis in Escherichia coli of the effects of in vivo CpG methylation catalyzed by the cloned murine maintenance methyltransferase.
Biochemical and biophysical research communications 1998;245(3):670-8.
1998: J A Wrobel; S F Chao; M J Conrad; J D Merker; Ronald Swanstrom; Gary J Pielak; Clyde A Hutchison
A genetic approach for identifying critical residues in the fingers and palm subdomains of HIV-1 reverse transcriptase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(2):638-45.
1997: T O Tollefsbol; Clyde A Hutchison
Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.
Journal of molecular biology 1997;269(4):494-504.
1997: W Shao; L Everitt; M Manchester; D D Loeb; Clyde A Hutchison; Ronald Swanstrom
Sequence requirements of the HIV-1 protease flap region determined by saturation mutagenesis and kinetic analysis of flap mutants.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2243-8.
1996: K S Pai; Dirk Bussiere; F Wang; Clyde A Hutchison; Stephen W White; Deepak Bastia
The structure and function of the replication terminator protein of Bacillus subtilis: identification of the 'winged helix' DNA-binding domain.
The EMBO journal 1996;15(12):3164-73.
1995: S N Peterson; C C Bailey; Jorgen Jensen; M B Borre; E S King; Kenneth Bott; Clyde A Hutchison
Characterization of repetitive DNA in the Mycoplasma genitalium genome: possible role in the generation of antigenic variation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11829-33.
1995: Claire M Fraser-Liggett; J D Gocayne; Owen R White; Mark D Adams; R A Clayton; Robert D Fleischmann; Carol Bult; A R Kerlavage; G Sutton; J M Kelley; R D Fritchman; J F Weidman; K V Small; M Sandusky; J Fuhrmann; D Nguyen; T R Utterback; D M Saudek; C A Phillips; J M Merrick; J F Tomb; B A Dougherty; Kenneth Bott; P C Hu; T S Lucier; S N Peterson; Hamilton O Smith; Clyde A Hutchison; J Craig Venter
The minimal gene complement of Mycoplasma genitalium.
Science (New York, N.Y.) 1995;270(5235):397-403.
1995: T O Tollefsbol; Clyde A Hutchison
Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized.
The Journal of biological chemistry 1995;270(31):18543-50.
1995: S N Peterson; T Lucier; K Heitzman; E A Smith; Kenneth Bott; P C Hu; Clyde A Hutchison
Genetic map of the Mycoplasma genitalium chromosome.
Journal of bacteriology 1995;177(11):3199-204.
1995: S F Chao; Voon Loong Chan; P Juranka; Andrew H Kaplan; Ronald Swanstrom; Clyde A Hutchison
Mutational sensitivity patterns define critical residues in the palm subdomain of the reverse transcriptase of human immunodeficiency virus type 1.
Nucleic acids research 1995;23(5):803-10.
1995: M D Moody; Steve Pettit; W Shao; L Everitt; D D Loeb; Clyde A Hutchison; Ronald Swanstrom
A side chain at position 48 of the human immunodeficiency virus type-1 protease flap provides an additional specificity determinant.
Virology 1995;207(2):475-85.
1995: C J Davies; Clyde A Hutchison
Insertion site specificity of the transposon Tn3.
Nucleic acids research 1995;23(3):507-14.
1994: T S Lucier; P Q Hu; S N Peterson; X Y Song; L Miller; K Heitzman; Kenneth Bott; Clyde A Hutchison; P C Hu
Construction of an ordered genomic library of Mycoplasma genitalium.
Gene 1994;150(1):27-34.
1994: N B Adey; S A Schichman; Douglas K. Graham; S N Peterson; Marshall Hall Edgell; Clyde A Hutchison
Rodent L1 evolution has been driven by a single dominant lineage that has repeatedly acquired new transcriptional regulatory sequences.
Molecular biology and evolution 1994;11(5):778-89.
1994: M Manchester; L Everitt; D D Loeb; Clyde A Hutchison; Ronald Swanstrom
Identification of temperature-sensitive mutants of the human immunodeficiency virus type 1 protease through saturation mutagenesis. Amino acid side chain requirements for temperature sensitivity.
The Journal of biological chemistry 1994;269(10):7689-95.
1994: N B Adey; T O Tollefsbol; A B Sparks; Marshall Hall Edgell; Clyde A Hutchison
Molecular resurrection of an extinct ancestral promoter for mouse L1.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1569-73.
1993: S N Peterson; P C Hu; Kenneth Bott; Clyde A Hutchison
A survey of the Mycoplasma genitalium genome by using random sequencing.
Journal of bacteriology 1993;175(24):7918-30.
1993: F Vanlerberghe; François Bonhomme; Clyde A Hutchison; Marshall Hall Edgell
A major difference between the divergence patterns within the lines-1 families in mice and voles.
Molecular biology and evolution 1993;10(4):719-31.
1993: S A Schichman; N B Adey; Marshall Hall Edgell; Clyde A Hutchison
L1 A-monomer tandem arrays have expanded during the course of mouse L1 evolution.
Molecular biology and evolution 1993;10(3):552-70.
1992: P L Deininger; M A Batzer; Clyde A Hutchison; Marshall Hall Edgell
Master genes in mammalian repetitive DNA amplification.
Trends in genetics : TIG 1992;8(9):307-11.
1992: Arnold B Barton; C J Davies; Clyde A Hutchison; David B Kaback
Cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the FUN52 gene, whose product has homology to protein kinases.
Gene 1992;117(1):137-40.
1992: S A Schichman; D M Severynse; Marshall Hall Edgell; Clyde A Hutchison
Strand-specific LINE-1 transcription in mouse F9 cells originates from the youngest phylogenetic subgroup of LINE-1 elements.
Journal of molecular biology 1992;224(3):559-74.
1992: D M Severynse; Clyde A Hutchison; Marshall Hall Edgell
Identification of transcriptional regulatory activity within the 5' A-type monomer sequence of the mouse LINE-1 retroposon.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;2(1):41-50.
1991: S N Peterson; N Schramm; P C Hu; Kenneth Bott; Clyde A Hutchison
A random sequencing approach for placing markers on the physical map of Mycoplasma genitalium.
Nucleic acids research 1991;19(21):6027-31.
1991: C J Davies; Clyde A Hutchison
A directed DNA sequencing strategy based upon Tn3 transposon mutagenesis: application to the ADE1 locus on Saccharomyces cerevisiae chromosome I.
Nucleic acids research 1991;19(20):5731-8.
1991: N B Adey; S A Schichman; Clyde A Hutchison; Marshall Hall Edgell
Composite of A and F-type 5' terminal sequences defines a subfamily of mouse LINE-1 elements.
Journal of molecular biology 1991;221(2):367-73.
1991: Frank H Burton; D D Loeb; Marshall Hall Edgell; Clyde A Hutchison
L1 gene conversion or same-site transposition.
Molecular biology and evolution 1991;8(5):609-19.
1991: Steve Pettit; J Simsic; D D Loeb; L Everitt; Clyde A Hutchison; Ronald Swanstrom
Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid.
The Journal of biological chemistry 1991;266(22):14539-47.
1991: N B Adey; Clyde A Hutchison
A rapid and versatile method to transfer an insert between single-stranded vectors and reverse its orientation.
Nucleic acids research 1991;19(12):3461-2.
1991: N B Adey; M B Comer; Marshall Hall Edgell; Clyde A Hutchison
Nucleotide sequence of a mouse full-length F-type L1 element.
Nucleic acids research 1991;19(9):2497.
1991: M Manchester; D D Loeb; L Everitt; M Moody; Clyde A Hutchison; Ronald Swanstrom
Analysis of temperature-sensitive mutants of the HIV-1 protease.
Advances in experimental medicine and biology 1991;306():493-7.
1991: Clyde A Hutchison; Ronald Swanstrom; D D Loeb
Complete mutagenesis of protein coding domains.
Methods in enzymology 1991;202():356-90.
1991: Alan T Bankier; S Beck; R Bohni; C M Brown; R Cerny; M S Chee; Clyde A Hutchison; T Kouzarides; John A Martignetti; E Preddie
The DNA sequence of the human cytomegalovirus genome.
DNA sequence : the journal of DNA sequencing and mapping 1991;2(1):1-12.
1990: Steven K Nordeen; B J Suh; B Kühnel; Clyde A Hutchison
Structural determinants of a glucocorticoid receptor recognition element.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1866-73.
1990: D D Loeb; Nancy Sung; R L Pesano; C J Sexton; Clyde A Hutchison; Joseph S Pagano
Plasmid origin of replication of herpesvirus papio: DNA sequence and enhancer function.
Journal of virology 1990;64(6):2876-83.
1990: C J Davies; J Trgovcich; Clyde A Hutchison
Homologue of TFIIS in yeast.
Nature 1990;345(6273):298.
1990: M S Chee; Alan T Bankier; S Beck; R Bohni; C M Brown; R Cerny; T Horsnell; Clyde A Hutchison; T Kouzarides; John A Martignetti
Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.
Current topics in microbiology and immunology 1990;154():125-69.
1989: Susan Erickson-Viitanen; J Manfredi; P Viitanen; D E Tribe; R Tritch; Clyde A Hutchison; D D Loeb; Ronald Swanstrom
Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease.
AIDS research and human retroviruses 1989;5(6):577-91.
1989: D D Loeb; Ronald Swanstrom; L Everitt; M Manchester; S E Stamper; Clyde A Hutchison
Complete mutagenesis of the HIV-1 protease.
Nature 1989;340(6232):397-400.
1989: D D Loeb; Clyde A Hutchison; Marshall Hall Edgell; W G Farmerie; Ronald Swanstrom
Mutational analysis of human immunodeficiency virus type 1 protease suggests functional homology with aspartic proteinases.
Journal of virology 1989;63(1):111-21.
1988: N C Casavant; Stephen Hardies; F D Funk; M B Comer; Marshall Hall Edgell; Clyde A Hutchison
Extensive movement of LINES ONE sequences in beta-globin loci of Mus caroli and Mus domesticus.
Molecular and cellular biology 1988;8(11):4669-74.
1988: R Murray; K Pederson; H Prosser; D Muller; Clyde A Hutchison; Jeffrey Frelinger
Random oligonucleotide mutagenesis: application to a large protein coding sequence of a major histocompatibility complex class I gene, H-2DP.
Nucleic acids research 1988;16(20):9761-73.
1988: Frank H Burton; D D Loeb; R A McGraw; Marshall Hall Edgell; Clyde A Hutchison
A directed nucleotide-sequencing approach for single-stranded vectors based on recloning intermediates of a progressive DNA synthesis reaction.
Gene 1988;67(2):159-68.
1988: R Murray; Clyde A Hutchison; Jeffrey Frelinger
Saturation mutagenesis of a major histocompatibility complex protein domain: identification of a single conserved amino acid important for allorecognition.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(10):3535-9.
1988: R W Padgett; Clyde A Hutchison; Marshall Hall Edgell
The F-type 5' motif of mouse L1 elements: a major class of L1 termini similar to the A-type in organization but unrelated in sequence.
Nucleic acids research 1988;16(2):739-49.
1987: J Snouwaert; D Bunick; Clyde A Hutchison; D M Fowlkes
Large numbers of random point and cluster mutations within the adenovirus VA I gene allow characterization of sequences required for efficient transcription.
Nucleic acids research 1987;15(20):8293-303.
1987: W R Shehee; S F Chao; D D Loeb; M B Comer; Clyde A Hutchison; Marshall Hall Edgell
Determination of a functional ancestral sequence and definition of the 5' end of A-type mouse L1 elements.
Journal of molecular biology 1987;196(4):757-67.
1987: W G Farmerie; D D Loeb; N C Casavant; Clyde A Hutchison; Marshall Hall Edgell; Ronald Swanstrom
Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli.
Science (New York, N.Y.) 1987;236(4799):305-8.
1987: Heinrich V Malling; M C Fater; J G Burkhart; Stephen Hardies; Clyde A Hutchison; Marshall Hall Edgell
Storage of spheroplasts at -70 degrees C for transfection with phi X174 RF DNA.
Gene analysis techniques 1987;4(2):23-6.
1987: R W Padgett; D D Loeb; L R Snyder; Marshall Hall Edgell; Clyde A Hutchison
The molecular organization of the beta-globin complex of the deer mouse, Peromyscus maniculatus.
Molecular biology and evolution 1987;4(1):30-45.
1987: Beverly Errede; M Company; Clyde A Hutchison
Ty1 sequence with enhancer and mating-type-dependent regulatory activities.
Molecular and cellular biology 1987;7(1):258-65.
1987: Marshall Hall Edgell; Stephen Hardies; D D Loeb; W R Shehee; R W Padgett; Frank H Burton; M B Comer; N C Casavant; F D Funk; Clyde A Hutchison
The L1 family in mice.
Progress in clinical and biological research 1987;251():107-29.
1986: Frank H Burton; D D Loeb; Clyde A Hutchison; Marshall Hall Edgell
A simple nonisotopic method for restriction mapping in single-stranded DNA cloning vectors based on taking timepoints during primed Klenow synthesis.
DNA (Mary Ann Liebert, Inc.) 1986;5(3):239-45.
1986: Stephen Hardies; S L Martin; C F Voliva; Clyde A Hutchison; Marshall Hall Edgell
An analysis of replacement and synonymous changes in the rodent L1 repeat family.
Molecular biology and evolution 1986;3(2):109-25.
1986: Clyde A Hutchison
Sequence gel reading with a portable computer.
Nucleic acids research 1986;14(4):1917.
1986: Clyde A Hutchison; S K Nordeen; K Vogt; Marshall Hall Edgell
A complete library of point substitution mutations in the glucocorticoid response element of mouse mammary tumor virus.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(3):710-4.
1986: Frank H Burton; D D Loeb; C F Voliva; S L Martin; Marshall Hall Edgell; Clyde A Hutchison
Conservation throughout mammalia and extensive protein-encoding capacity of the highly repeated DNA long interspersed sequence one.
Journal of molecular biology 1986;187(2):291-304.
1986: D D Loeb; R W Padgett; Stephen Hardies; W R Shehee; M B Comer; Marshall Hall Edgell; Clyde A Hutchison
The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons.
Molecular and cellular biology 1986;6(1):168-82.
1985: Beverly Errede; M Company; J D Ferchak; Clyde A Hutchison; W S Yarnell
Activation regions in a yeast transposon have homology to mating type control sequences and to mammalian enhancers.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(16):5423-7.
1985: Frank H Burton; D D Loeb; S F Chao; Clyde A Hutchison; Marshall Hall Edgell
Transposition of a long member of the L1 major interspersed DNA family into the mouse beta globin gene locus.
Nucleic acids research 1985;13(14):5071-84.
1985: S L Phillips; N C Casavant; Clyde A Hutchison; Marshall Hall Edgell
An empirical method for the evaluation of the quality of genomic DNA libraries.
Nucleic acids research 1985;13(8):2699-708.
1985: S L Martin; C F Voliva; Stephen Hardies; Marshall Hall Edgell; Clyde A Hutchison
Tempo and mode of concerted evolution in the L1 repeat family of mice.
Molecular biology and evolution 1985;2(2):127-40.
1984: S Gillam; C R Astell; P Jahnke; Clyde A Hutchison; M Smith
Construction and properties of a ribosome-binding site mutation in gene E of phi X174 bacteriophage.
Journal of virology 1984;52(3):892-6.
1984: M G Farace; A Hill; M Tripodi; R W Padgett; G Raschella; R Gambari; Antonio Fantoni; Clyde A Hutchison; Marshall Hall Edgell
Molecular cloning and sequence analysis of a cDNA coding for the mouse alpha-like embryonic globin chain x.
Gene 1984;31(1-3):241-5.
1984: Clyde A Hutchison; Stephen Hardies; R W Padgett; S Weaver; Marshall Hall Edgell
The mouse globin pseudogene beta h3 is descended from a premammalian delta-globin gene.
The Journal of biological chemistry 1984;259(20):12881-9.
1984: C F Voliva; S L Martin; Clyde A Hutchison; Marshall Hall Edgell
Dispersal process associated with the L1 family of interspersed repetitive DNA sequences.
Journal of molecular biology 1984;178(4):795-813.
1984: S K Nordeen; V G Schaefer; Marshall Hall Edgell; Clyde A Hutchison; L D Shultz; M Swift
Evaluations of wasted mouse fibroblasts and SV-40 transformed human fibroblasts as models of ataxia telangiectasia in vitro.
Mutation research 1984;140(4):219-22.
1984: S J Phillips; Stephen Hardies; C L Jahn; Marshall Hall Edgell; Clyde A Hutchison
The complete nucleotide sequence of a beta-globin-like structure, beta h2, from the [Hbb]d mouse BALB/c.
The Journal of biological chemistry 1984;259(12):7947-54.
1984: M G Farace; B A Brown; Giuseppe Raschellà; J Alexander; R Gambari; Antonio Fantoni; Stephen Hardies; Clyde A Hutchison; Marshall Hall Edgell
The mouse beta h1 gene codes for the z chain of embryonic hemoglobin.
The Journal of biological chemistry 1984;259(11):7123-8.
1984: S L Martin; C F Voliva; Frank H Burton; Marshall Hall Edgell; Clyde A Hutchison
A large interspersed repeat found in mouse DNA contains a long open reading frame that evolves as if it encodes a protein.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(8):2308-12.
1984: Stephen Hardies; Marshall Hall Edgell; Clyde A Hutchison
Evolution of the mammalian beta-globin gene cluster.
The Journal of biological chemistry 1984;259(6):3748-56.
1984: A Hill; Stephen Hardies; S J Phillips; M G Davis; Clyde A Hutchison; Marshall Hall Edgell
Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.
The Journal of biological chemistry 1984;259(6):3739-47.
1984: C T White; Stephen Hardies; Clyde A Hutchison; Marshall Hall Edgell
The diagonal-traverse homology search algorithm for locating similarities between two sequences.
Nucleic acids research 1984;12(1 Pt 2):751-66.
1983: C F Voliva; C L Jahn; M B Comer; Clyde A Hutchison; Marshall Hall Edgell
The L1Md long interspersed repeat family in the mouse: almost all examples are truncated at one end.
Nucleic acids research 1983;11(24):8847-59.
1983: Stephen Hardies; D E Axelrod; Marshall Hall Edgell; Clyde A Hutchison
Phenotypic variation associated with molecular alterations at a cluster of thymidine kinase genes.
Molecular and cellular biology 1983;3(7):1163-71.
1982: Michael D Topal; Clyde A Hutchison; M S Baker
DNA precursors in chemical mutagenesis: a novel application of DNA sequencing.
Nature 1982;298(5877):863-5.
1982: B A Brown; R W Padgett; Stephen Hardies; Clyde A Hutchison; Marshall Hall Edgell
beta-globin transcript found in induced murine erythroleukemia cells is homologous to the beta h0 and beta h1 genes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(9):2753-7.
1981: S Weaver; M B Comer; C L Jahn; Clyde A Hutchison; Marshall Hall Edgell
The adult beta-globin genes of the "single" type mouse C57BL.
Cell 1981;24(2):403-11.
1981: Nancy Haigwood; C L Jahn; Clyde A Hutchison; Marshall Hall Edgell
Locations of three repetitive sequence families found in BALB/c adult beta-globin clones.
Nucleic acids research 1981;9(5):1133-50.
1980: J A Lautenberger; Marshall Hall Edgell; Clyde A Hutchison
The nucleotide sequence recognized by the BstEII restriction endonuclease.
Gene 1980;12(1-2):171-4.
1980: C L Jahn; Clyde A Hutchison; S J Phillips; S Weaver; Nancy Haigwood; C F Voliva; Marshall Hall Edgell
DNA sequence organization of the beta-globin complex in the BALB/c mouse.
Cell 1980;21(1):159-68.
1980: Nigel Brown; Clyde A Hutchison; M Smith
The specific non-symmetrical sequence recognized by restriction endonuclease MboII.
Journal of molecular biology 1980;140(1):143-8.
1980: J A Lautenberger; C T White; Nancy Haigwood; Marshall Hall Edgell; Clyde A Hutchison
The recognition site of type II restriction enzyme BglI is interrupted.
Gene 1980;9(3-4):213-31.
1979: Stanley Martin Hattman; C Gribbin; Clyde A Hutchison
In vivo methylation of bacteriophage phi X174 DNA.
Journal of virology 1979;32(3):845-51.
1979: J A Lautenberger; Marshall Hall Edgell; Clyde A Hutchison; G N Godson
The DNA sequence on bacteriophage G4 recognized by the Escherichia coli B restriction enzyme.
Journal of molecular biology 1979;131(4):871-5.
1979: S Gillam; P Jahnke; C Astell; S Phillips; Clyde A Hutchison; M Smith
Defined transversion mutations at a specific position in DNA using synthetic oligodeoxyribonucleotides as mutagens.
Nucleic acids research 1979;6(9):2973-85.
1979: N C Kan; J A Lautenberger; Marshall Hall Edgell; Clyde A Hutchison
The nucleotide sequence recognized by the Escherichia coli K12 restriction and modification enzymes.
Journal of molecular biology 1979;130(2):191-209.
1979: S Weaver; Nancy Haigwood; Clyde A Hutchison; Marshall Hall Edgell
DNA fragments of the Mus musculus beta globin haplotypes Hbbs and Hbbd.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(3):1385-9.
1978: G M Air; A R Coulson; J C Fiddes; T Friedmann; Clyde A Hutchison; Frederick Sanger; P M Slocombe; A J Smith
Nucleotide sequence of the F protein coding region of bacteriophage phiX174 and the amino acid sequence of its product.
Journal of molecular biology 1978;125(2):247-54.
1978: Frederick Sanger; A R Coulson; T Friedmann; G M Air; B G Barrell; Nigel Brown; J C Fiddes; Clyde A Hutchison; P M Slocombe; M Smith
The nucleotide sequence of bacteriophage phiX174.
Journal of molecular biology 1978;125(2):225-46.
1978: Clyde A Hutchison; S Phillips; Marshall Hall Edgell; S Gillam; P Jahnke; M Smith
Mutagenesis at a specific position in a DNA sequence.
The Journal of biological chemistry 1978;253(18):6551-60.
1978: J A Lautenberger; N C Kan; D Lackey; S Linn; Marshall Hall Edgell; Clyde A Hutchison
Recognition site of Escherichia coli B restriction enzyme on phi XsB1 and simian virus 40 DNAs: an interrupted sequence.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(5):2271-5.
1977: D K Freymeyer; P R Shank; Marshall Hall Edgell; Clyde A Hutchison; T C Vanaman
Amino acid sequence of the small core protein from bacteriophage phiX174.
Biochemistry 1977;16(21):4550-6.
1977: Frederick Sanger; G M Air; B G Barrell; Nigel Brown; A R Coulson; C A Fiddes; Clyde A Hutchison; P M Slocombe; M Smith
Nucleotide sequence of bacteriophage phi X174 DNA.
Nature 1977;265(5596):687-95.
1977: M Smith; Nigel Brown; G M Air; B G Barrell; A R Coulson; Clyde A Hutchison; Frederick Sanger
DNA sequence at the C termini of the overlapping genes A and B in bacteriophage phi X174.
Nature 1977;265(5596):702-5.
1976: B G Barrell; G M Air; Clyde A Hutchison
Overlapping genes in bacteriophage phiX174.
Nature 1976;264(5581):34-41.
1975: steven potter; John Newbold; Clyde A Hutchison; Marshall Hall Edgell
Specific cleavage analysis of mammalian mitochondrial DNA.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(11):4496-500.
1974: Clyde A Hutchison; John Newbold; steven potter; Marshall Hall Edgell
Maternal inheritance of mammalian mitochondrial DNA.
Nature 1974;251(5475):536-8.
1973: C Y Chen; Clyde A Hutchison; Marshall Hall Edgell
Isolation and genetic localization of three phi-X174 promoter regions.
Nature: New biology 1973;243(129):233-6.
1972: J H Middleton; Marshall Hall Edgell; Clyde A Hutchison
Specific fragments of phi X174 deoxyribonucleic acid produced by a restriction enzyme from Haemophilus aegyptius, endonuclease Z.
Journal of virology 1972;10(1):42-50.
1972: Marshall Hall Edgell; Clyde A Hutchison; M Sclair
Specific endonuclease R fragments of bacteriophage phiX174 deoxyribonucleic acid.
Journal of virology 1972;9(4):574-82.
1971: Clyde A Hutchison; Marshall Hall Edgell
Genetic assay for small fragments of bacteriophage phi X174 deoxyribonucleic acid.
Journal of virology 1971;8(2):181-9.
1971: Clyde A Hutchison; R L Sinsheimer
Requirement of protein synthesis for bacteriophage phi X174 superinfection exclusion.
Journal of virology 1971;8(1):121-4.
1970: H Walter; Marshall Hall Edgell; Clyde A Hutchison
Separation of bacteriophage phiX174 mutants by countercurrent distribution in a two-polymer acqueous phase system.
Biochimica et biophysica acta 1970;204(1):248-51.
1969: Marshall Hall Edgell; Clyde A Hutchison; R L Sinsheimer
The process of infection with bacteriophage phi-X174. 28. Removal of the spike proteins from the phage capsid.
Journal of molecular biology 1969;42(3):547-57.
1967: Clyde A Hutchison; Marshall Hall Edgell; R L Sinsheimer
The process of infection with bacteriophage phi-X174. XII. Phenotypic mixing between electrophoretic mutants of phi-X174.
Journal of molecular biology 1967;23(3):553-75.
1966: Clyde A Hutchison; R L Sinsheimer
The process of infection with bacteriophage phi-X174. X. Mutations in a phi-X Lysis gene.
Journal of molecular biology 1966;18(3):429-47.
1963: Clyde A Hutchison; R L SINSHEIMER
KINETICS OF BACTERIOPHAGE RELEASE BY SINGLE CELLS OF PHI X174-INFECTED E. COLI.
Journal of molecular biology 1963;7():206-8.
1958: C R WOESE; H J MOROWITZ; Clyde A Hutchison
Analysis of action of L-alanine analogues in spore germination.
Journal of bacteriology 1958;76(6):578-88.