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Risto Huupponen

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Finland

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Pasi Lampela; Piia Lavikainen; Esko Leskinen; Risto Huupponen; Sirpa Hartikainen
Comprehensive geriatric assessment decreases prevalence of orthostatic hypotension in older persons.
Pasi Lampela; Piia Lavikainen; J Simon Bell; J Arturo Garcia-Horsman; Risto Huupponen; Sirpa Hartikainen
Anticholinergic drug use, serum anticholinergic activity, and adverse drug events among older people: a population-based study.
Eveliina Upmeier; Maarit Jaana Korhonen; Arja Helin-Salmivaara; Risto Huupponen
Statin use among older Finns stratified according to cardiovascular risk.

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All Publications

2013: Pasi Lampela; Piia Lavikainen; Esko Leskinen; Risto Huupponen; Sirpa Hartikainen
Comprehensive geriatric assessment decreases prevalence of orthostatic hypotension in older persons.
Scandinavian journal of public health 2013;41(4):351-8.
2013: Pasi Lampela; Piia Lavikainen; J Simon Bell; J Arturo Garcia-Horsman; Risto Huupponen; Sirpa Hartikainen
Anticholinergic drug use, serum anticholinergic activity, and adverse drug events among older people: a population-based study.
Drugs & aging 2013;30(5):321-30.
2013: Eveliina Upmeier; Maarit Jaana Korhonen; Arja Helin-Salmivaara; Risto Huupponen
Statin use among older Finns stratified according to cardiovascular risk.
European journal of clinical pharmacology 2013;69(2):261-7.
2012: Kristiina Mansikkaniemi; Jukka Marniemi; Tapani Rönnemaa; Liisa Saarikoski; Simo Taimela; Leena Taittonen; Risto Telama; Jorma Viikari; Joelle Benessiano; Mirja Hirvensalo; Mikko Hurme; Risto Huupponen; Antti Jula; Markus Juonala; Mika Kähönen; Terho Lehtimäki; Ziad Mallat; Olli T Raitakari
Cross-sectional associations between physical activity and selected coronary heart disease risk factors in young adults. The Cardiovascular Risk in Young Finns Study.
Annals of medicine 2012;44(7):733-44.
2012: Juho R H Raiko; Risto Huupponen; Antti Jula; Markus Juonala; Mika Kähönen; Terho Lehtimäki; Britt-Marie Loo; Mervi Oikonen; Liisa Saarikoski; Niina Siitonen; Jorma Viikari; Maria Wendelin-Saarenhovi; Olli T Raitakari
Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2012;224(1):208-12.
2012: Mervi Oikonen; Liisa Saarikoski; Ilkka Seppälä; Niina Siitonen; Jorma S A Viikari; Maria Wendelin-Saarenhovi; Nina Hutri-Kähönen; Risto Huupponen; Antti Jula; Markus Juonala; Mika Kähönen; Terho Lehtimäki; Britt-Marie Loo; Leo-Pekka Lyytikäinen; Olli T Raitakari
Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study.
Atherosclerosis 2012;223(2):497-503.
2012: Virpi Sulosaari; Maija Hupli; Risto Huupponen; Satu Kajander; Helena Leino-Kilpi
Nurse students' medication competence--an integrative review of the associated factors.
Nurse education today 2012;32(4):399-405.
2012: Juha Koskinen; Britt-Marie Loo; Costan G Magnussen; Jukka Marniemi; Olli T Raitakari; Liisa A Saarikoski; Jorma S A Viikari; Risto Huupponen; Antti Jula; Mika Kähönen; Markus Juonala
Association of liver enzymes with metabolic syndrome and carotid atherosclerosis in young adults. The Cardiovascular Risk in Young Finns Study.
Annals of medicine 2012;44(2):187-95.
2012: Arja Helin-Salmivaara; Seppo Y T Junnila; Maarit J Korhonen; Petri Lehenkari; Pertti J Neuvonen; Päivi Ruokoniemi; Risto Huupponen
Statins and hip fracture prevention--a population based cohort study in women.
PloS one 2012;7(10):e48095.
2011: Maarit Jaana Korhonen; Arja Helin-Salmivaara; Risto Huupponen
Dynamics of long-term statin therapy.
European journal of clinical pharmacology 2011;67(9):925-31.
2011: Markus Juonala; Mika Kähönen; Mika Kivimäki; Juha Koskinen; Tomi Laitinen; Terho Lehtimäki; Leo-Pekka Lyytikäinen; Costan G Magnussen; Mervi Oikonen; Liisa A Saarikoski; Leena Taittonen; Jorma S A Viikari; Risto Huupponen; Olli T Raitakari
A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2011;217(1):234-9.
2011: Päivi Ruokoniemi; Maarit J Korhonen; Arja Helin-Salmivaara; Piia Lavikainen; Antti Jula; Seppo Y T Junnila; Raimo Kettunen; Risto Huupponen
Statin adherence and the risk of major coronary events in patients with diabetes: a nested case-control study.
British journal of clinical pharmacology 2011;71(5):766-76.
2011: Jarna C Hannukainen; Ronald Borra; Kaisa Linderborg; Heikki Paavo Kallio; Jan Kiss; Virva Lepomäki; Kari K Kalliokoski; Urho M Kujala; Jaakko Kaprio; Olli J Heinonen; Markku Komu; Riitta Parkkola; Markku Ahotupa; Terho Lehtimäki; Risto Huupponen; Patricia Iozzo; Pirjo Nuutila
Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity.
Journal of hepatology 2011;54(3):545-52.
2010: Liisa A Saarikoski; Risto Huupponen; Jorma S A Viikari; Jukka Marniemi; Markus Juonala; Mika Kähönen; Olli T Raitakari
Adiponectin is related with carotid artery intima-media thickness and brachial flow-mediated dilatation in young adults--the Cardiovascular Risk in Young Finns Study.
Annals of medicine 2010;42(8):603-11.
2010: Pasi Lampela; Sirpa Hartikainen; Piia Lavikainen; Raimo Sulkava; Risto Huupponen
Effects of medication assessment as part of a comprehensive geriatric assessment on drug use over a 1-year period: a population-based intervention study.
Drugs & aging 2010;27(6):507-21.
2010: Arja Helin-Salmivaara; Piia T Lavikainen; Maarit J Korhonen; Heli Halava; Jaana E Martikainen; Leena K Saastamoinen; Lauri Virta; Timo Klaukka; Risto Huupponen
Pattern of statin use among 10 cohorts of new users from 1995 to 2004: a register-based nationwide study.
The American journal of managed care 2010;16(2):116-22.
2009: Maarit Jaana Korhonen; Risto Huupponen; Päivi Ruokoniemi; Arja Helin-Salmivaara
Protopathic bias in observational studies on statin effectiveness.
European journal of clinical pharmacology 2009;65(11):1167-8.
2009: Heli Halava; Arja Helin-Salmivaara; Jouni Junnila; Risto Huupponen
Selective prescribing of simvastatin and atorvastatin by patient characteristics at treatment initiation over a 7-year period in Finland.
European journal of clinical pharmacology 2009;65(9):927-33.
2009: Arja Helin-Salmivaara; Piia Lavikainen; Päivi Ruokoniemi; Maarit Korhonen; Risto Huupponen
Persistence with statin therapy in diabetic and non-diabetic persons: a nation-wide register study in 1995-2005 in Finland.
Diabetes research and clinical practice 2009;84(1):e9-e11.
2009: Antti Viljanen; Riikka Lautamäki; Mikko Järvisalo; Riitta Parkkola; Risto Huupponen; Terho Lehtimäki; Tapani Rönnemaa; Olli T Raitakari; Patricia Iozzo; Pirjo Nuutila
Effects of weight loss on visceral and abdominal subcutaneous adipose tissue blood-flow and insulin-mediated glucose uptake in healthy obese subjects.
Annals of medicine 2009;41(2):152-60.
2008: Päivi Ruokoniemi; Arja Helin-Salmivaara; Timo Klaukka; Pertti J Neuvonen; Risto Huupponen
Shift of statin use towards the elderly in 1995-2005: a nation-wide register study in Finland.
British journal of clinical pharmacology 2008;66(3):405-10.
2008: Aapo Lehtonen; Risto Huupponen; Jaakko Tuomilehto; Sirkku Lavonius; Seija Arve; Hannu Isoaho; Ilpo Huhtaniemi; Reijo S Tilvis
Serum testosterone but not leptin predicts mortality in elderly men.
Age and ageing 2008;37(4):461-4.
2008: Rahman Shiri; Svetlana Solovieva; Kirsti Husgafvel-Pursiainen; Simo Taimela; Liisa A Saarikoski; Risto Huupponen; Jorma Viikari; Olli T Raitakari; Eira Viikari-Juntura
The association between obesity and the prevalence of low back pain in young adults: the Cardiovascular Risk in Young Finns Study.
American journal of epidemiology 2008;167(9):1110-9.
2008: Arja Helin-Salmivaara; Piia Lavikainen; Maarit J Korhonen; Heli Halava; Seppo Y T Junnila; Raimo Kettunen; Pertti J Neuvonen; Jaana E Martikainen; Päivi Ruokoniemi; Leena K Saastamoinen; Lauri Virta; Risto Huupponen
Long-term persistence with statin therapy: a nationwide register study in Finland.
Clinical therapeutics 2008;30 Pt 2():2228-40.
2008: Tuire Tirkkonen; Anna Ryynänen; Tero Vahlberg; Kerttu Irjala; Timo Klaukka; Risto Huupponen; Kari Laine
Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study.
Drug safety : an international journal of medical toxicology and drug experience 2008;31(3):231-40.
2007: Liisa A Viikari; Risto Huupponen; Jorma S A Viikari; Jukka Marniemi; Carita Eklund; Mikko Hurme; Terho Lehtimäki; Mika Kivimäki; Olli T Raitakari
Relationship between leptin and C-reactive protein in young Finnish adults.
The Journal of clinical endocrinology and metabolism 2007;92(12):4753-8.
2007: Olli T Raitakari; Tapani Rönnemaa; Risto Huupponen; Liisa Viikari; Meng Fan; Jukka Marniemi; Nina Hutri-Kähönen; Jorma S A Viikari; Terho Lehtimäki; Terho Lehtimäkimd
Variation of the transcription factor 7-like 2 (TCF7L2) gene predicts impaired fasting glucose in healthy young adults: the Cardiovascular Risk in Young Finns Study.
Diabetes care 2007;30(9):2299-301.
2007: Arja Helin-Salmivaara; Sami Saarelainen; Juha M Grönroos; Risto Vesalainen; Timo Klaukka; Risto Huupponen
Risk of upper gastrointestinal events with the use of various NSAIDs: a case-control study in a general population.
Scandinavian journal of gastroenterology 2007;42(8):923-32.
2007: Riikka Lautamäki; Tapani Rönnemaa; Risto Huupponen; Terho Lehtimäki; Patricia Iozzo; K E Juhani Airaksinen; Juhani Knuuti; Pirjo Nuutila
Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease.
Metabolism: clinical and experimental 2007;56(7):881-6.
2007: Pasi Lampela; Sirpa Hartikainen; Raimo Sulkava; Risto Huupponen
Adverse drug effects in elderly people -- a disparity between clinical examination and adverse effects self-reported by the patient.
European journal of clinical pharmacology 2007;63(5):509-15.
2007: Arja Helin-Salmivaara; Teppo Huttunen; Juha M Grönroos; Timo Klaukka; Risto Huupponen
Risk of serious upper gastrointestinal events with concurrent use of NSAIDs and SSRIs: a case-control study in the general population.
European journal of clinical pharmacology 2007;63(4):403-8.
2006: Arja Helin-Salmivaara; Arja Virtanen; Risto Vesalainen; Juha M Grönroos; Timo Klaukka; Juhana E Idänpään-Heikkilä; Risto Huupponen
NSAID use and the risk of hospitalization for first myocardial infarction in the general population: a nationwide case-control study from Finland.
European heart journal 2006;27(14):1657-63.
2005: Kirsi A Virtanen; Patricia Iozzo; Kirsti Hällsten; Risto Huupponen; Riitta Parkkola; Tuula Janatuinen; Fredrik Lönnqvist; Tapio Viljanen; Tapani Rönnemaa; Peter Lönnroth; Juhani Knuuti; Ele Ferrannini; Pirjo Nuutila
Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study.
Diabetes 2005;54(9):2720-6.
2005: Antti Jula; Jukka Marniemi; Tapani Rönnemaa; Arja Virtanen; Risto Huupponen
Effects of diet and simvastatin on fatty acid composition in hypercholesterolemic men: a randomized controlled trial.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1952-9.
2005: Arja Helin-Salmivaara; Risto Huupponen; Arja Virtanen; Jari Lammela; Timo Klaukka
Frequent prescribing of drugs with potential gastrointestinal toxicity among continuous users of non-steroidal anti-inflammatory drugs.
European journal of clinical pharmacology 2005;61(5-6):425-31.
2005: Outi Paija; Kari Laine; Eeva-Riitta Kultalahti; Mika Leinonen; Risto Huupponen; Ariel Gordin; Kari Reinikainen
Entacapone increases levodopa exposure and reduces plasma levodopa variability when used with Sinemet CR.
Clinical neuropharmacology 2005;28(3):115-9.
2005: Arja Helin-Salmivaara; Risto Huupponen; Arja Virtanen; Timo Klaukka
Adoption of celecoxib and rofecoxib: a nationwide database study.
Journal of clinical pharmacy and therapeutics 2005;30(2):145-52.
2004: Risto Huupponen; Markku Anttila; Juha Rouru; Hanna Kanerva; Tatu A Miettinen; Mika Scheinin
Pharmacokinetics of deramciclane and N-desmethylderamciclane after single and repeated oral doses in healthy volunteers.
International journal of clinical pharmacology and therapeutics 2004;42(8):449-55.
2003: Kari Laine; Outi Ahokoski; Risto Huupponen; Jutta Hänninen; Sanna Palovaara; Jori Ruuskanen; Harry Björklund; Markku Anttila; Juha Rouru
Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone.
European journal of clinical pharmacology 2003;59(10):761-6.
2003: Arja Helin-Salmivaara; Risto Huupponen; Timo Klaukka; Kalle Hoppu
Focusing on changing clinical practice to enhance rational prescribing--collaboration and networking enable comprehensive approaches.
Health policy (Amsterdam, Netherlands) 2003;66(1):1-10.
2003: Arja Helin-Salmivaara; Timo Klaukka; Risto Huupponen
Heavy users of non-steroidal anti-inflammatory drugs: a nationwide prescription database study in Finland.
European journal of clinical pharmacology 2003;59(5-6):477-82.
2003: Jan Sundell; Risto Huupponen; Olli T Raitakari; Pirjo Nuutila; Juhani Knuuti
High serum leptin is associated with attenuated coronary vasoreactivity.
Obesity research 2003;11(6):776-82.
2003: Kirsi A Virtanen; Kirsti Hällsten; Riitta Parkkola; Tuula Janatuinen; Fredrik Lönnqvist; Tapio Viljanen; Tapani Rönnemaa; Juhani Knuuti; Risto Huupponen; Peter Lönnroth; Pirjo Nuutila
Differential effects of rosiglitazone and metformin on adipose tissue distribution and glucose uptake in type 2 diabetic subjects.
Diabetes 2003;52(2):283-90.
2003: Risto Huupponen; Outi Paija; Markku Salonen; Harry Björklund; Juha Rouru; Markku Anttila
Pharmacokinetics of deramciclane, a novel anxiolytic agent, after intravenous and oral administration.
Drugs in R&D 2003;4(6):339-45.
2002: Kirsi A Virtanen; Peter Lönnroth; Riitta Parkkola; Pauliina Peltoniemi; Markku R Asola; Tapio Viljanen; Tuula Tolvanen; Juhani Knuuti; Tapani Rönnemaa; Risto Huupponen; Pirjo Nuutila
Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans.
The Journal of clinical endocrinology and metabolism 2002;87(8):3902-10.
2002: Antti Jula; Jukka Marniemi; Risto Huupponen; Arja Virtanen; Merja Rastas; Tapani Rönnemaa
Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2002;287(5):598-605.
2002: Kirsi A Virtanen; Merja Haaparanta; Tove Grönroos; J Bergman; Olof Solin; Juha Rouru; Pirjo Nuutila; Risto Huupponen
2-[(18)F]fluoro-2-deoxy-D-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats.
Diabetes, obesity & metabolism 2002;4(1):60-8.
2001: Kirsi A Virtanen; Pauliina Peltoniemi; Päivi Marjamäki; Markku R Asola; Lena Strindberg; Riitta Parkkola; Risto Huupponen; Juhani Knuuti; Peter Lönnroth; Pirjo Nuutila
Human adipose tissue glucose uptake determined using [(18)F]-fluoro-deoxy-glucose ([(18)F]FDG) and PET in combination with microdialysis.
Diabetologia 2001;44(12):2171-9.
2001: Outi Ahokoski; Kerttu Irjala; Mikko O Taalikka; P Manninen; Kaija Halonen; Lauri Kangas; Eeva Salminen; Risto Huupponen; Harry Scheinin
Pharmacokinetics of finrozole (MPV-2213ad), a novel selective aromatase inhibitor, in healthy men.
British journal of clinical pharmacology 2001;52(6):702-4.
2001: Elina Vainio-Jylhä; Marja-Liisa Vuori; K Pyykkö; Risto Huupponen
Plasma concentration of topically applied betaxolol in elderly glaucoma patients.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2001;17(3):207-13.
2001: V Luukkaa; Eriika Savontaus; Juha Rouru; Kirsi A Virtanen; Olivier Boss; Ilpo Huhtaniemi; Markku Koulu; Ullamari Pesonen; Risto Huupponen
Effects of estrous cycle and steroid replacement on the expression of leptin and uncoupling proteins in adipose tissue in the rat.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2001;15(2):103-12.
2000: Mirja Somer; Jaana Kallio; Ullamari Pesonen; K Pyykkö; Risto Huupponen; Mika Scheinin
Influence of hydroxychloroquine on the bioavailability of oral metoprolol.
British journal of clinical pharmacology 2000;49(6):549-54.
2000: Eriika Savontaus; Juha Rouru; Kimmo Malminiemi; V Luukkaa; Ullamari Pesonen; Markku Koulu; Risto Huupponen
Effects of chronic celiprolol treatment on brown fat, feeding, and drinking in fa/fa Zucker rats.
Pharmacology, biochemistry, and behavior 2000;65(4):719-24.
2000: Mikko Pietilä; Kimmo Malminiemi; Risto Huupponen; Juha Rouru; Kari Pulkki; E Pere; Liisa-Maria Voipio-Pulkki
Celiprolol augments the effect of physical exercise on insulin sensitivity and serum lipid levels in chronic heart failure.
European journal of heart failure 2000;2(1):81-90.
2000: V Luukkaa; Juha Rouru; Outi Ahokoski; Harry Scheinin; Kerttu Irjala; Risto Huupponen
Acute inhibition of oestrogen biosynthesis does not affect serum leptin levels in young men.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(2):164-9.
2000: Kari Laine; Markku Anttila; Risto Huupponen; O Mäki-Ikola; EH Heinonen
Multiple-dose pharmacokinetics of selegiline and desmethylselegiline suggest saturable tissue binding.
Clinical neuropharmacology 2000;23(1):22-7.
1999: Hanna Kanerva; O Kilkku; Antti Helminen; Juha Rouru; Mika Scheinin; Risto Huupponen; Imre Klebovich; Sándor Drabant; Arto Urtti
Pharmacokinetics and safety of deramciclane during multiple oral dosing.
International journal of clinical pharmacology and therapeutics 1999;37(12):589-97.
1999: Hanna Kanerva; O Kilkku; EH Heinonen; Antti Helminen; Juha Rouru; S Tarpila; Mika Scheinin; Risto Huupponen; Imre Klebovich; Sándor Drabant; Arto Urtti
The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers.
Biopharmaceutics & drug disposition 1999;20(7):327-34.
1999: Risto Vesalainen; Mikko Pietilä; Kari U O Tahvanainen; Tuomas Jartti; Mika Teräs; Kjell Någren; Pertti Lehikoinen; Risto Huupponen; Heikki Ukkonen; Markku Saraste; Juhani Knuuti; Liisa-Maria Voipio-Pulkki
Cardiac positron emission tomography imaging with [11C]hydroxyephedrine, a specific tracer for sympathetic nerve endings, and its functional correlates in congestive heart failure.
The American journal of cardiology 1999;84(5):568-74.
1999: Juha Rouru; Ariel Gordin; Risto Huupponen; Sakke Huhtala; Eriika Savontaus; K Korpela; Kari Reinikainen; Mika Scheinin
Pharmacokinetics of oral entacapone after frequent multiple dosing and effects on levodopa disposition.
European journal of clinical pharmacology 1999;55(6):461-7.
1999: Outi Ahokoski; Arja Virtanen; Veli Kairisto; Harry Scheinin; Risto Huupponen; Kerttu Irjala
Biological day-to-day variation and reference change limits of serum cortisol and aldosterone in healthy young men on unrestricted diets.
Clinical chemistry 1999;45(7):1097-9.
1999: Kari Laine; Markku Anttila; Antti Helminen; H Karnani; Risto Huupponen
Dose linearity study of selegiline pharmacokinetics after oral administration: evidence for strong drug interaction with female sex steroids.
British journal of clinical pharmacology 1999;47(3):249-54.
1999: Outi Ahokoski; Kerttu Irjala; Sakke Huhtala; Eeva Salminen; Harry Scheinin; Risto Huupponen
A double-blind study of MPV-2213ad, a novel aromatase inhibitor, in healthy male subjects.
European journal of clinical pharmacology 1999;55(1):27-34.
1998: V Luukkaa; Ullamari Pesonen; Ilpo Huhtaniemi; A Lehtonen; R Tilvis; Jaakko Tuomilehto; Markku Koulu; Risto Huupponen
Inverse correlation between serum testosterone and leptin in men.
The Journal of clinical endocrinology and metabolism 1998;83(9):3243-6.
1998: T Teirmaa; V Luukkaa; Juha Rouru; Markku Koulu; Risto Huupponen
Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(2):190-4.
1998: Elina Vainio-Jylhä; Marja-Liisa Vuori; Timo J Kaila; Risto Huupponen
Aqueous humour concentration and the intraocular pressure-lowering effect of topical betaxolol before cataract surgery.
European journal of clinical pharmacology 1998;54(5):389-92.
1998: Outi Ahokoski; Arja Virtanen; Risto Huupponen; Harry Scheinin; Eeva Salminen; Veli Kairisto; Kerttu Irjala
Biological day-to-day variation and daytime changes of testosterone, follitropin, lutropin and oestradiol-17beta in healthy men.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1998;36(7):485-91.
1998: Eriika Savontaus; Juha Rouru; Olivier Boss; Risto Huupponen; Markku Koulu
Differential regulation of uncoupling proteins by chronic treatments with beta 3-adrenergic agonist BRL 35135 and metformin in obese fa/fa Zucker rats.
Biochemical and biophysical research communications 1998;246(3):899-904.
1998: Eriika Savontaus; Ullamari Pesonen; Juha Rouru; Risto Huupponen; Markku Koulu
Effects of ZD7114, a selective beta3-adrenoceptor agonist, on neuroendocrine mechanisms controlling energy balance.
European journal of pharmacology 1998;347(2-3):265-74.
1998: Outi Ahokoski; Kerttu Irjala; Risto Huupponen; Kaija Halonen; Eeva Salminen; Harry Scheinin
Hormonal effects of MPV-2213ad, a new selective aromatase inhibitor, in healthy male subjects. A phase I study.
British journal of clinical pharmacology 1998;45(2):141-6.
1998: Kimmo Malminiemi; Jorma Lahtela; O Malminiemi; K Ala-Kaila; Risto Huupponen
Insulin sensitivity in a long-term crossover trial with celiprolol and other antihypertensive agents.
Journal of cardiovascular pharmacology 1998;31(1):140-5.
1997: Kari Laine; Markku Anttila; EH Heinonen; Antti Helminen; Risto Huupponen; O Mäki-Ikola; Kari Reinikainen; Mika Scheinin
Lack of adverse interactions between concomitantly administered selegiline and citalopram.
Clinical neuropharmacology 1997;20(5):419-33.
1997: Kirsi A Virtanen; Juha Rouru; V Hänninen; Eriika Savontaus; T Rouvari; T Teirmaa; Markku Koulu; Risto Huupponen
Chronic treatment with BRL 35135 potentiates the action of insulin on lipid metabolism.
European journal of pharmacology 1997;332(2):215-8.
1997: Eriika Savontaus; A Raasmaja; Juha Rouru; Markku Koulu; Ullamari Pesonen; Raine Virtanen; Juha-Matti Savola; Risto Huupponen
Anti-obesity effect of MPV-1743 A III, a novel imidazoline derivative, in genetic obesity.
European journal of pharmacology 1997;328(2-3):207-15.
1997: Juha Rouru; Leena Anttila; P Koskinen; TA Penttilä; Kerttu Irjala; Risto Huupponen; Markku Koulu
Serum leptin concentrations in women with polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 1997;82(6):1697-700.
1997: PE Grönroos; Kerttu Irjala; Risto Huupponen; Harry Scheinin; J Forsström; JJ Forsström
A medication database--a tool for detecting drug interactions in hospital.
European journal of clinical pharmacology 1997;53(1):13-7.
1995: Risto Huupponen; S Karhuvaara; Markku Anttila; L Vuorilehto; Harry Scheinin
Buccal delivery of an alpha 2-adrenergic receptor antagonist, atipamezole, in humans.
Clinical pharmacology and therapeutics 1995;58(5):506-11.
1995: Juha Rouru; Markku Koulu; Juha Peltonen; E Santti; V Hänninen; Ullamari Pesonen; Risto Huupponen
Effects of metformin treatment on glucose transporter proteins in subcellular fractions of skeletal muscle in (fa/fa) Zucker rats.
British journal of pharmacology 1995;115(7):1182-7.
1995: Juha Rouru; Ullamari Pesonen; Markku Koulu; Risto Huupponen; E Santti; K Virtanen; T Rouvari; M Jhanwar-Uniyal
Anorectic effect of metformin in obese Zucker rats: lack of evidence for the involvement of neuropeptide Y.
European journal of pharmacology 1995;273(1-2):99-106.
1994: E Santti; Risto Huupponen; Juha Rouru; V Hänninen; Ullamari Pesonen; M Jhanwar-Uniyal; Markku Koulu
Potentiation of the anti-obesity effect of the selective beta 3-adrenoceptor agonist BRL 35135 in obese Zucker rats by exercise.
British journal of pharmacology 1994;113(4):1231-6.
1994: K K Lahdes; Risto Huupponen; Timo J Kaila
Ocular effects and systemic absorption of cyclopentolate eyedrops after canthal and conventional application.
Acta ophthalmologica 1994;72(6):698-702.
1994: E Santti; T Rouvari; Juha Rouru; Risto Huupponen; Markku Koulu
Effect of chronic treatment with ICI D7114, a selective beta 3-adrenoceptor agonist, on macronutrient selection and brown adipose tissue thermogenesis in Sprague-Dawley rats.
Pharmacology & toxicology 1994;75(3-4):166-9.
1993: Jaana Kallio; Päivi Rautava; Risto Huupponen; Heikki Korvenranta
Severe hyponatremia caused by intranasal desmopressin for nocturnal enuresis.
Acta paediatrica (Oslo, Norway : 1992) 1993;82(10):881-2.
1993: Timo J Kaila; S Karhuvaara; Risto Huupponen; E Iisalo
The analysis of plasma kinetics and beta-receptor binding and -blocking activity of timolol following its small intravenous dose.
International journal of clinical pharmacology, therapy, and toxicology 1993;31(7):351-7.
1993: Juha Rouru; K Isaksson; E Santti; Risto Huupponen; Markku Koulu
Metformin and brown adipose tissue thermogenetic activity in genetically obese Zucker rats.
European journal of pharmacology 1993;246(1):67-71.
1993: K Lahdes; Risto Huupponen; Timo J Kaila; D Monti; Marco Fabrizio Saettone; Lotta Salminen
Plasma concentrations and ocular effects of cyclopentolate after ocular application of three formulations.
British journal of clinical pharmacology 1993;35(5):479-83.
1993: Juha Rouru; Ullamari Pesonen; K Isaksson; Risto Huupponen; Markku Koulu
Effect of chronic treatment with TFMPP, a 5-HT1 receptor agonist, on food intake, weight gain, plasma insulin and neuropeptide mRNA expression in obese Zucker rats.
European journal of pharmacology 1993;234(2-3):191-8.
1993: Juha Rouru; Risto Huupponen; E Santti; Markku Koulu
Effect of subchronic metformin treatment on macronutrient selection in genetically obese Zucker rats.
Pharmacology & toxicology 1993;72(4-5):300-3.
1993: Risto Huupponen; K Pyykkö; Markku Koulu; Juha Rouru
Metformin and liver glycogen synthase activity in obese Zucker rats.
Research communications in chemical pathology and pharmacology 1993;79(2):219-27.
1992: Risto Huupponen; P Ojala-Karlsson; Juha Rouru; Markku Koulu
Determination of metformin in plasma by high-performance liquid chromatography.
Journal of chromatography 1992;583(2):270-3.
1992: Ullamari Pesonen; Risto Huupponen; Juha Rouru; Markku Koulu
Hypothalamic neuropeptide expression after food restriction in Zucker rats: evidence of persistent neuropeptide Y gene activation.
Brain research. Molecular brain research 1992;16(3-4):255-60.
1992: E A Sotaniemi; Frej Stenbäck; Leila Risteli; J A Vuori; Arja Rautio; Risto Huupponen; Juha Risteli
Effect of insulin on serum amino-terminal propeptide of type III procollagen in non-insulin-dependent diabetes mellitus.
Diabetes research and clinical practice 1992;17(3):209-15.
1992: Ullamari Pesonen; J Jolkkonen; Risto Huupponen; Markku Koulu
Differential hypothalamic arginine vasopressin response to glucocorticoid receptor antagonism in lean and obese Zucker rats.
Neuroendocrinology 1992;56(2):271-7.
1992: Ullamari Pesonen; Markku Koulu; Oskari Heikinheimo; Risto Huupponen
The glucocorticoid antagonist mifepristone reveals abnormal regulation of the adrenocortical system in obese Zucker rats.
The Journal of endocrinology 1992;132(3):425-31.
1992: K Lahdes; Risto Huupponen; Timo J Kaila; T Ali-Melkkilä; Lotta Salminen; M Saari
Systemic absorption of ocular cyclopentolate in children.
German journal of ophthalmology 1992;1(1):16-8.
1992: Risto Huupponen; A Lehtonen; M Vähätalo
Effect of doxazosin on insulin sensitivity in hypertensive non-insulin dependent diabetic patients.
European journal of clinical pharmacology 1992;43(4):365-8.
1992: Risto Huupponen; Timo J Kaila; Marco Fabrizio Saettone; D Monti; E Ilsalo; Lotta Salminen; O Oksala
The effect of some macromolecular ionic complexes on the pharmacokinetics and -dynamics of ocular cyclopentolate in rabbits.
Journal of ocular pharmacology 1992;8(1):59-67.
1992: Juha Rouru; Risto Huupponen; Ullamari Pesonen; Markku Koulu
Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese Zucker rats.
Life sciences 1992;50(23):1813-20.
1991: Risto Huupponen; K Pyykkö; S Ala-Uotila; E Sotaniemi
Activity of xenobiotic metabolizing liver enzymes in Zucker rats.
Research communications in chemical pathology and pharmacology 1991;72(3):307-14.
1991: Ullamari Pesonen; Juha Rouru; Risto Huupponen; Markku Koulu
Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats.
Brain research. Molecular brain research 1991;10(3):267-72.
1991: Risto Huupponen; Timo J Kaila; K Lahdes; Lotta Salminen; E Iisalo
Systemic absorption of ocular timolol in poor and extensive metabolizers of debrisoquine.
Journal of ocular pharmacology 1991;7(2):183-7.
1991: Timo J Kaila; Risto Huupponen; S Karhuvaara; P Havula; Mika Scheinin; E Iisalo; Lotta Salminen
Beta-blocking effects of timolol at low plasma concentrations.
Clinical pharmacology and therapeutics 1991;49(1):53-8.
1990: Risto Huupponen; Markku Koulu; Ullamari Pesonen
Hypothalamic 5-hydroxytryptamine metabolism is not influenced by streptozotocin-diabetes induced at neonatal age.
Experimental and clinical endocrinology 1990;96(3):328-30.
1990: Jaana Kallio; Risto Huupponen; J Viikari
Debrisoquine hydroxylation polymorphism in diabetic patients.
Diabetes research (Edinburgh, Scotland) 1990;15(3):125-9.
1990: Markku Koulu; Risto Huupponen; H Hänninen; Ullamari Pesonen; Juha Rouru; T Seppälä
Hypothalamic neurochemistry and feeding behavioral responses to clonidine, an alpha-2-agonist, and to trifluoromethylphenylpiperazine, a putative 5-hydroxytryptamine-1B agonist, in genetically obese Zucker rats.
Neuroendocrinology 1990;52(5):503-10.
1990: Jaana Kallio; Risto Huupponen; M Seppälä; E Säkö; E Iisalo
The effects of beta-adrenoceptor antagonists and levomepromazine on the metabolic ratio of debrisoquine.
British journal of clinical pharmacology 1990;30(4):638-43.
1990: E A Sotaniemi; E Vierimaa; Risto Huupponen; I Karvonen; M J Vuoti; K Rytömaa
Insulin and sulphonylurea in the therapy of type 2 diabetes.
Diabetes research and clinical practice 1990;8(3):243-51.
1990: Jaana Kallio; Risto Huupponen; K Pyykkö
The relationship between debrisoquine oxidation phenotype and the pharmacokinetics of chlorpropamide.
European journal of clinical pharmacology 1990;39(1):93-5.
1990: K Lahdes; Risto Huupponen; Timo J Kaila; Lotta Salminen; E Iisalo
Systemic absorption of ocular scopolamine in patients.
Journal of ocular pharmacology 1990;6(1):61-6.
1990: I Karvonen; Raija Sormunen; Risto Huupponen; E A Sotaniemi
Reduced glucose-6-phosphorylase and NADPH generating enzyme activities associated with glibenclamide induced hypoglycemia and hypoinsulinemia in genetically obese mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1990;44(6):307-16.
1989: I Karvonen; Risto Huupponen; K M Niemelä; E Sotaniemi
Effects of phenobarbital on hepatic glucose metabolism and NADPH production in Zucker rats.
Archives internationales de pharmacodynamie et de thérapie 1989;302():40-8.
1989: S Karhuvaara; Timo J Kaila; Risto Huupponen
Beta-adrenoceptor antagonist activities and binding affinities of timolol enantiomers in rat atria.
The Journal of pharmacy and pharmacology 1989;41(9):649-50.
1989: P Aula; Timo J Kaila; Risto Huupponen; Lotta Salminen; E Iisalo
Prostaglandin F2 alpha binding to bovine ocular and synthetic melanins in vitro.
Pharmacology & toxicology 1989;65(2):100-3.
1989: Timo J Kaila; Risto Huupponen; Lotta Salminen; E Iisalo
Systemic absorption of ophthalmic cyclopentolate.
American journal of ophthalmology 1989;107(5):562-4.
1989: Risto Huupponen; I Karvonen; E Sotaniemi
Activity of hepatic glucose phosphorylating and NADPH generating enzymes in Zucker rats.
Diabetes research (Edinburgh, Scotland) 1989;10(3):143-6.
1989: I Karvonen; Jari H Stengård; Risto Huupponen; Frej Stenbäck; E A Sotaniemi
Effects of enzyme induction therapy on glucose and drug metabolism in obese mice model of non-insulin dependent diabetes mellitus.
Diabetes research (Edinburgh, Scotland) 1989;10(2):85-92.
1989: Lotta Salminen; R Lindberg; H R Toivari; Risto Huupponen; Timo J Kaila; E Iisalo
Prevalence of debrisoquine oxidation phenotypes in glaucoma patients.
International ophthalmology 1989;13(1-2):91-3.
1988: Jaana Kallio; R Lindberg; Risto Huupponen; E Iisalo
Debrisoquine oxidation in a Finnish population: the effect of oral contraceptives on the metabolic ratio.
British journal of clinical pharmacology 1988;26(6):791-5.
1988: K Lahdes; Timo J Kaila; Risto Huupponen; Lotta Salminen; E Iisalo
Systemic absorption of topically applied ocular atropine.
Clinical pharmacology and therapeutics 1988;44(3):310-4.
1988: Risto Huupponen; Markku Koulu; U M Jaakkola
Somatostatin concentrations in discrete hypothalamic nuclei of genetically obese Zucker rats.
Experimental and clinical endocrinology 1988;91(3):277-81.
1988: Risto Huupponen
Significance of insulin receptors in the action of sulphonylurea drugs.
Annals of clinical research 1988;20(5):373-9.
1988: P Aula; Timo J Kaila; Risto Huupponen; Lotta Salminen
Timolol binding to bovine ocular melanin in vitro.
Journal of ocular pharmacology 1988;4(1):29-36.
1987: R L Lindberg; Risto Huupponen; S Viljanen; KK Pihlajamäki
Ethanol and the absorption of oral penicillin in man.
International journal of clinical pharmacology, therapy, and toxicology 1987;25(10):536-8.
1987: Risto Huupponen; T Kaila; Lotta Salminen; Arto Urtti
The pharmacokinetics of ocularly applied timolol in rabbits.
Acta ophthalmologica 1987;65(1):63-6.
1986: Timo J Kaila; Risto Huupponen; Lotta Salminen
Effects of eyelid closure and nasolacrimal duct occlusion on the systemic absorption of ocular timolol in human subjects.
Journal of ocular pharmacology 1986;2(4):365-9.
1985: Timo J Kaila; Lotta Salminen; Risto Huupponen
Systemic absorption of topically applied ocular timolol.
Journal of ocular pharmacology 1985;1(1):79-83.
1985: Risto Huupponen; S Karhuvaara; P Seppälä
Effect of guar gum on glipizide absorption in man.
European journal of clinical pharmacology 1985;28(6):717-9.
1984: R L Lindberg; Risto Huupponen; P Huovinen
Rapid high-pressure liquid chromatographic method for analysis of phenoxymethylpenicillin in human serum.
Antimicrobial agents and chemotherapy 1984;26(3):300-2.
1984: Risto Huupponen; P Seppälä; E Iisalo
Effect of guar gum, a fibre preparation, on digoxin and penicillin absorption in man.
European journal of clinical pharmacology 1984;26(2):279-81.
1982: Risto Huupponen; P Seppälä; E Iisalo
Glipizide pharmacokinetics and response in diabetics.
International journal of clinical pharmacology, therapy, and toxicology 1982;20(9):417-22.