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Luigi Aurisicchio

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Giuseppe Roscilli; Ottaviano Serlupi-Crescenzi; Ashraf Virmani; Luigi Aurisicchio; Arianna Di Napoli; Rita Mancini; Emanuele Marra; Federica Mori; Gennaro Ciliberto
Carnitines slow down tumor development of colon cancer in the DMH-chemical carcinogenesis mouse model.
Claudia Diaz; Elisa Scarselli; Luigi Aurisicchio; Ansuman Bagchi; Alberto Chiappori; Gennaro Ciliberto; Jason Clark; Sheri Dubey; Jesus C Fabregas; Arthur Fridman; Nicola La Monica; John Marshall; Alberto J Montero
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors.
Emanuele Marra; Fabio Palombo; Gennaro Ciliberto; Luigi Aurisicchio
Kinesin spindle protein SiRNA slows tumor progression.

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All Publications

2013: Giuseppe Roscilli; Ottaviano Serlupi-Crescenzi; Ashraf Virmani; Luigi Aurisicchio; Arianna Di Napoli; Rita Mancini; Emanuele Marra; Federica Mori; Gennaro Ciliberto
Carnitines slow down tumor development of colon cancer in the DMH-chemical carcinogenesis mouse model.
Journal of cellular biochemistry 2013;114(7):1665-73.
2013: Claudia Diaz; Elisa Scarselli; Luigi Aurisicchio; Ansuman Bagchi; Alberto Chiappori; Gennaro Ciliberto; Jason Clark; Sheri Dubey; Jesus C Fabregas; Arthur Fridman; Nicola La Monica; John Marshall; Alberto J Montero
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors.
Journal of translational medicine 2013;11():62.
2013: Emanuele Marra; Fabio Palombo; Gennaro Ciliberto; Luigi Aurisicchio
Kinesin spindle protein SiRNA slows tumor progression.
Journal of cellular physiology 2013;228(1):58-64.
2012: Emanuele Marra; Julio Padron; Marco Tripodi; Paolo Turrini; Gennaro Ciliberto; Luigi Aurisicchio
Intrablastocyst injection with human CD34+/CD133+ cells increase survival of immunocompetent fumarylacetoacetate hydrolase knockout mice.
Laboratory animals 2012;46(4):280-6.
2012: Luigi Aurisicchio; Fabrizio Carlomosti; Maurizio Alimandi; Claudia De Vitis; Zeynep Gunes; Laura Luberto; Rita Mancini; Emanuele Marra; Giuseppe Mesiti; Alessia Noto; Giuseppe Roscilli; Gennaro Ciliberto
Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors.
Journal of cellular physiology 2012;227(10):3381-8.
2012: Luigi Aurisicchio; Rita Mancini; Emanuele Marra; Giuseppe Roscilli; Gennaro Ciliberto
The promise of anti-ErbB3 monoclonals as new cancer therapeutics.
Oncotarget 2012;3(8):744-58.
2012: Luigi Aurisicchio; Gennaro Ciliberto
Genetic cancer vaccines: current status and perspectives.
Expert opinion on biological therapy 2012;12(8):1043-58.
2012: Francesca Belleudi; Luigi Aurisicchio; Luigi Fattore; Maria Giovagnoli; Rita Mancini; Emanuele Marra; Francesca Mazzetta; Maria Rosaria Torrisi; Gennaro Ciliberto
Monoclonal antibody-induced ErbB3 receptor internalization and degradation inhibits growth and migration of human melanoma cells.
Cell cycle (Georgetown, Tex.) 2012;11(7):1455-67.
2011: Sridhar Dharmapuri; N La Monica; E Marra; Fabio Palombo; D Peruzzi; C Toniatti; M Yong; S R Bartz; A J Bett; C A Buser; G Ciliberto; Luigi Aurisicchio
Intratumor RNA interference of cell cycle genes slows down tumor progression.
Gene therapy 2011;18(7):727-33.
2011: Rita Mancini; Salvatore Mariotta; Emanuele Marra; Giuseppe Mesiti; Alessia Noto; Lara Pisani; Erino A Rendina; Alberto Ricci; Giuseppe Roscilli; Luigi Ruco; Giuseppe Viglietto; Pietro Zoppoli; Andrea Affuso; Claudio Andreetti; Luigi Aurisicchio; Pasquale De Luca; Claudia De Vitis; Arianna Di Napoli; Enrico Giarnieri; Maria Giovagnoli; Carmelo Laudanna; Donatella Malanga; Gennaro Ciliberto
Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment.
PloS one 2011;6(7):e21320.
2010: Daniela Peruzzi; Alessandra Gavazza; Giuseppe Mesiti; George Lubas; Elisa Scarselli; Antonella Conforti; Claus Bendtsen; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
A vaccine targeting telomerase enhances survival of dogs affected by B-cell lymphoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(8):1559-67.
2010: Luigi Aurisicchio; Gennaro Ciliberto
Patented cancer vaccines: the promising leads.
Expert opinion on therapeutic patents 2010;20(5):647-60.
2010: Antonella Conforti; Barbara Cipriani; Daniela Peruzzi; Sridhar Dharmapuri; Ekambar R Kandimalla; Sudhir Agrawal; Federica Mori; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
A TLR9 agonist enhances therapeutic effects of telomerase genetic vaccine.
Vaccine 2010;28(20):3522-30.
2010: Daniela Peruzzi; Giuseppe Mesiti; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
Telomerase and HER-2/neu as targets of genetic cancer vaccines in dogs.
Vaccine 2010;28(5):1201-8.
2009: Angelos D Gritzapis; Arthur Fridman; Sonia Perez; Nicola La Monica; Michael Papamichail; Luigi Aurisicchio; Constantin N Baxevanis
HER-2/neu (657-665) represents an immunogenic epitope of HER-2/neu oncoprotein with potent antitumor properties.
Vaccine 2009;28(1):162-70.
2009: Sridhar Dharmapuri; Daniela Peruzzi; Luigi Aurisicchio
Engineered adenovirus serotypes for overcoming anti-vector immunity.
Expert opinion on biological therapy 2009;9(10):1279-87.
2009: Sridhar Dharmapuri; Daniela Peruzzi; Carmela Mennuni; Francesco Calvaruso; Saverio Giampaoli; Gaetano Barbato; Ekambar R Kandimalla; Sudhir Agrawal; Elisa Scarselli; Giuseppe Mesiti; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(10):1804-13.
2009: Antonella Conforti; Daniela Peruzzi; Patrizia Giannetti; Antonella Biondo; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
A novel mouse model for evaluation and prediction of HLA-A2-restricted CEA cancer vaccine responses.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(7):744-54.
2009: Daniela Peruzzi; Federica Mori; Antonella Conforti; Lazzaro Domenico; Emanuele De Rinaldis; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
MMP11: a novel target antigen for cancer immunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4104-13.
2009: Sridhar Dharmapuri; Luigi Aurisicchio; Antonella Biondo; Natalie Welsh; Gennaro Ciliberto; Nicola La Monica
Antiapoptotic small interfering RNA as potent adjuvant of DNA vaccination in a mouse mammary tumor model.
Human gene therapy 2009;20(6):589-97.
2009: Elena Fattori; Luigi Aurisicchio; Immacolata Zampaglione; Mirko Arcuri; Manuela Cappelletti; Barbara Cipriani; Carmela Mennuni; FRANCESCO CALVARUSO; Maurizio Nuzzo; Gennaro Ciliberto; Paolo Monaci; Nicola La Monica
ErbB2 genetic cancer vaccine in nonhuman primates: relevance of single nucleotide polymorphisms.
Human gene therapy 2009;20(3):253-65.
2009: Luigi Aurisicchio; Daniela Peruzzi; Antonella Conforti; Sridhar Dharmapuri; Antonella Biondo; Saverio Giampaoli; Arthur Fridman; Ansu Bagchi; Christopher T Winkelmann; Raymond Gibson; Ekambar R Kandimalla; Sudhir Agrawal; Gennaro Ciliberto; Nicola La Monica
Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(5):1575-84.
2009: Daniela Peruzzi; Sridhar Dharmapuri; Agostino Cirillo; Bruno Ercole Bruni; Alfredo Nicosia; Riccardo Cortese; Stefano Colloca; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
A novel chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines.
Vaccine 2009;27(9):1293-300.
2009: Federica Mori; Patrizia Giannetti; Daniela Peruzzi; Domenico Lazzaro; Saverio Giampaoli; Howard Kaufman; Gennaro Ciliberto; Nicola La Monica; Luigi Aurisicchio
A therapeutic cancer vaccine targeting carcinoembryonic antigen in intestinal carcinomas.
Human gene therapy 2009;20(2):125-36.
2009: Paolo Uva; Luigi Aurisicchio; James Watters; Andrey Loboda; Amit Kulkarni; John Castle; Fabio Palombo; Valentina Viti; Giuseppe Mesiti; Valentina Zappulli; Laura Marconato; Francesca Abramo; Gennaro Ciliberto; Armin Lahm; Nicola La Monica; Emanuele de Rinaldis
Comparative expression pathway analysis of human and canine mammary tumors.
BMC genomics 2009;10():135.
2008: Mirko Arcuri; Manuela Cappelletti; Immacolata Zampaglione; Luigi Aurisicchio; Alfredo Nicosia; Gennaro Ciliberto; Elena Fattori
Synergistic effect of gene-electro transfer and adjuvant cytokines in increasing the potency of hepatitis C virus genetic vaccination.
The journal of gene medicine 2008;10(9):1048-54.
2007: Andrea Facciabene; Luigi Aurisicchio; Leonardo Elia; Fabio Palombo; Carmela Mennuni; Gennaro Ciliberto; Nicola La Monica
Vectors encoding carcinoembryonic antigen fused to the B subunit of heat-labile enterotoxin elicit antigen-specific immune responses and antitumor effects.
Vaccine 2007;26(1):47-58.
2007: Ramon E Camacho; Richard Wnek; Paul Fischer; Kashmira Shah; Dennis Zaller; Andrea Woods; Nicola La Monica; Luigi Aurisicchio; Patricia Fitzgerald-Bocarsly; Gloria C Koo
Characterization of the NOD/scid-[Tg]DR1 mouse expressing HLA-DRB1*01 transgene: a model of SCID-hu mouse for vaccine development.
Experimental hematology 2007;35(8):1219-30.
2007: Luigi Aurisicchio; Carmela Mennuni; Patrizia Giannetti; FRANCESCO CALVARUSO; Maurizio Nuzzo; Barbara Cipriani; Fabio Palombo; Paolo MONACI; Gennaro Ciliberto; Nicola La Monica
Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates.
International journal of cancer. Journal international du cancer 2007;120(11):2290-300.
2007: Leonardo Elia; Luigi Aurisicchio; Andrea Facciabene; Patrizia Giannetti; Gennaro Ciliberto; Nicola La Monica; Fabio Palombo
CD4+CD25+ regulatory T-cell-inactivation in combination with adenovirus vaccines enhances T-cell responses and protects mice from tumor challenge.
Cancer gene therapy 2007;14(2):201-10.
2006: Patrizia Giannetti; Andrea Facciabene; Nicola La Monica; Luigi Aurisicchio
Individual mouse analysis of the cellular immune response to tumor antigens in peripheral blood by intracellular staining for cytokines.
Journal of immunological methods 2006;316(1-2):84-96.
2006: Leonardo Elia; Carmela Mennuni; marianna storto; Silvia Podda; FRANCESCO CALVARUSO; Valentina Salucci; Luigi Aurisicchio; Alessia Scarito; Gennaro Ciliberto; Nicola La Monica; Fabio Palombo
Genetic vaccines against Ep-CAM break tolerance to self in a limited subset of subjects: initial identification of predictive biomarkers.
European journal of immunology 2006;36(5):1337-49.
2006: Andrea Facciabene; Luigi Aurisicchio; Leonardo Elia; Fabio Palombo; Carmela Mennuni; Gennaro Ciliberto; Nicola La Monica
DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection.
Human gene therapy 2006;17(1):81-92.
2005: Carmela Mennuni; FRANCESCO CALVARUSO; Andrea Facciabene; Luigi Aurisicchio; marianna storto; Elisa Scarselli; Gennaro Ciliberto; Nicola La Monica
Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA.
International journal of cancer. Journal international du cancer 2005;117(3):444-55.
2005: Luigi Aurisicchio; Amedeo De Tomassi; Nicola La Monica; Gennaro Ciliberto; Cinzia Traboni; Fabio Palombo
Regulated and liver-specific tamarin alpha interferon gene delivery by a helper-dependent adenoviral vector.
Journal of virology 2005;79(11):6772-80.
2004: Melanie Fiedler; Florian Rödicker; Valentina Salucci; Mengji Lu; Luigi Aurisicchio; Uta Dahmen; Li Jun; Olaf Dirsch; Brigitte M Pützer; Fabio Palombo; Michael Roggendorf
Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-alpha) and IFN-gamma: IFN-alpha but not IFN-gamma reduces woodchuck hepatitis virus replication in chronic infection in vivo.
Journal of virology 2004;78(18):10111-21.
2004: Andrea Facciabene; Luigi Aurisicchio; Nicola La Monica
Baculovirus vectors elicit antigen-specific immune responses in mice.
Journal of virology 2004;78(16):8663-72.
2002: Valentina Salucci; Alessia Scarito; Luigi Aurisicchio; Stefania Lamartina; Giancarlo Nicolaus; Saverio Giampaoli; Odalys Gonzalez Paz; Carlo Toniatti; Hermann Bujard; Wolfgang Hillen; Gennaro Ciliberto; Fabio Palombo
Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.
Gene therapy 2002;9(21):1415-21.
2002: Valentina Salucci; Mengji Lu; Luigi Aurisicchio; Nicola La Monica; Michael Roggendorf; Fabio Palombo
Expression of a new woodchuck IFN-alpha gene by a helper-dependent adenoviral vector in woodchuck hepatitis virus-infected primary hepatocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(10):1027-34.
2001: Luigi Aurisicchio; Hermann Bujard; Wolfgang Hillen; Riccardo Cortese; Gennaro Ciliberto; Nicola La Monica; Fabio Palombo
Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector.
Gene therapy 2001;8(24):1817-25.
2001: Luigi Aurisicchio; A Ceccacci; Nicola La Monica; Fabio Palombo; Cinzia Traboni
Tamarin alpha-interferon is active in mouse liver upon intramuscular gene delivery.
The journal of gene medicine 2001;3(4):394-402.
2001: Laura Santodonato; Maria Ferrantini; Fabio Palombo; Luigi Aurisicchio; Paola Delmastro; Nicola La Monica; S Di Marco; Gennaro Ciliberto; MX Du; Milton Taylor; Filippo Belardelli
Antitumor activity of recombinant adenoviral vectors expressing murine IFN-alpha in mice injected with metastatic IFN-resistant tumor cells.
Cancer gene therapy 2001;8(1):63-72.
2000: Luigi Aurisicchio; Paola Delmastro; Valentina Salucci; O G Paz; P Rovere; Gennaro Ciliberto; Nicola La Monica; Fabio Palombo
Liver-specific alpha 2 interferon gene expression results in protection from induced hepatitis.
Journal of virology 2000;74(10):4816-23.