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Yuying Hwang

Research Profile

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Myocardium

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Publications

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Lee S Rosen; Poornima Shubhakar; Min Zhu; Emily Chan; Hongjie Deng; Gregory Friberg; Jill Gilbert; Yuying C Hwang; Deva Mahalingam; Ian McCaffery; Shaunita A Michael; Alain C Mita; Monica M Mita; Marilyn Mulay; Igor Puzanov; John Sarantopoulos
Safety and pharmacokinetics of ganitumab (AMG 479) combined with sorafenib, panitumumab, erlotinib, or gemcitabine in patients with advanced solid tumors.
Roy S Herbst; Razelle Kurzrock; David S Hong; Manuel Valdivieso; Cheng-Pang Hsu; Lovely Goyal; Gloria Juan; Yuying C Hwang; Susan Wong; John S Hill; Greg Friberg; Patricia M LoRusso
A first-in-human study of conatumumab in adult patients with advanced solid tumors.
Roy S Herbst; David Hong; Linnea Chap; Razelle Kurzrock; Edward Jackson; Jeffrey M Silverman; Erik Rasmussen; Yu-Nien Sun; Don Zhong; Yuying C Hwang; Jeffrey L Evelhoch; Jonathan D Oliner; Ngocdiep Le; Lee S Rosen
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors.

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All Publications

2012: Lee S Rosen; Poornima Shubhakar; Min Zhu; Emily Chan; Hongjie Deng; Gregory Friberg; Jill Gilbert; Yuying C Hwang; Deva Mahalingam; Ian McCaffery; Shaunita A Michael; Alain C Mita; Monica M Mita; Marilyn Mulay; Igor Puzanov; John Sarantopoulos
Safety and pharmacokinetics of ganitumab (AMG 479) combined with sorafenib, panitumumab, erlotinib, or gemcitabine in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(12):3414-27.
2010: Roy S Herbst; Razelle Kurzrock; David S Hong; Manuel Valdivieso; Cheng-Pang Hsu; Lovely Goyal; Gloria Juan; Yuying C Hwang; Susan Wong; John S Hill; Greg Friberg; Patricia M LoRusso
A first-in-human study of conatumumab in adult patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(23):5883-91.
2009: Roy S Herbst; David Hong; Linnea Chap; Razelle Kurzrock; Edward Jackson; Jeffrey M Silverman; Erik Rasmussen; Yu-Nien Sun; Don Zhong; Yuying C Hwang; Jeffrey L Evelhoch; Jonathan D Oliner; Ngocdiep Le; Lee S Rosen
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(21):3557-65.
2009: Radha Ananthakrishnan; Michiyo Kaneko; Yuying C Hwang; Nosirudeen Quadri; Teodoro Gomez; Qing Li; Casper Caspersen; Ravichandran Ramasamy
Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore.
American journal of physiology. Heart and circulatory physiology 2009;296(2):H333-41.
2008: loredana bucciarelli; Radha Ananthakrishnan; Yuying C Hwang; Michiyo Kaneko; Fei Song; David R Sell; Christopher Strauch; Vincent M Monnier; Shi Fang Yan; Ann Marie Schmidt; Ravichandran Ramasamy
RAGE and modulation of ischemic injury in the diabetic myocardium.
Diabetes 2008;57(7):1941-51.
2008: Qing Li; Yuying C Hwang; Radha Ananthakrishnan; Peter J Oates; Dennis Guberski; Ravichandran Ramasamy
Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts.
Cardiovascular diabetology 2008;7():33.
2006: loredana bucciarelli; Michiyo Kaneko; Radha Ananthakrishnan; Evis Harja; Larisse K Lee; Yuying C Hwang; Shulamit Lerner; Soliman Bakr; Qing Li; Yan Lu; Fei Song; Wu Qu; Teodoro Gomez; Yu Shan Zou; Shi Fang Yan; Ann Marie Schmidt; Ravichandran Ramasamy
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury.
Circulation 2006;113(9):1226-34.
2005: Michiyo Kaneko; loredana bucciarelli; Yuying C Hwang; Larisee Lee; Shi Fang Yan; Ann Marie Schmidt; Ravichandran Ramasamy
Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury.
Annals of the New York Academy of Sciences 2005;1043():702-9.
2005: Priya Pillutla; Yuying C Hwang; Ayanna Augustus; Masayoshi Yokoyama; Hiroaki Yagyu; Thomas P Johnston; Michiyo Kaneko; Ravichandran Ramasamy; Ira J Goldberg
Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy.
American journal of physiology. Endocrinology and metabolism 2005;288(6):E1229-35.
2005: Yuying C Hwang; Seán Shaw; Michiyo Kaneko; Heather Redd; Mario B Marrero; Ravichandran Ramasamy
Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):795-7.
2004: Yuying C Hwang; Michiyo Kaneko; Soliman Bakr; Hui Liao; Yan Lu; Erin R Lewis; Shi Du Yan; Setsuko Ii; Mitsuo Itakura; Liu Rui; Hal Skopicki; Shunichi Homma; Ann Marie Schmidt; Peter J Oates; Matthias Szabolcs; Ravichandran Ramasamy
Central role for aldose reductase pathway in myocardial ischemic injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1192-9.
2004: Ravichandran Ramasamy; Yuying C Hwang; Yulin Liu; Ni Huiping Son; Ningsheng Ma; John Parkinson; Robert R Sciacca; Arline Albala; Niloo Edwards; Matthias Szabolcs; Paul J Cannon
Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 during ischemia-reperfusion in isolated perfused hearts.
Circulation 2004;109(13):1668-73.
2003: Yuying C Hwang; Soliman Bakr; Craig A Ellery; Peter J Oates; Ravichandran Ramasamy
Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(15):2331-3.
2002: Yuying C Hwang; Soliman Bakr; Ravichandran Ramasamy; Steven Bergmann
Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium.
Coronary artery disease 2002;13(6):313-8.
2002: Yuying C Hwang; Sanai Sato; Jen-Yue Tsai; Shi Du Yan; Soliman Bakr; Huiping Zhang; Peter J Oates; Ravichandran Ramasamy
Aldose reductase activation is a key component of myocardial response to ischemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):243-5.
2001: Ravichandran Ramasamy; Yuying C Hwang; J Whang; Steven Bergmann
Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4.
American journal of physiology. Heart and circulatory physiology 2001;281(1):H290-7.
2000: Shi Du Yan; Y Zhu; E D Stern; Yuying C Hwang; O Hori; S Ogawa; M P Frosch; E S Connolly; R McTaggert; David J Pinsky; S Clarke; David M Stern; Ravichandran Ramasamy
Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress.
The Journal of biological chemistry 2000;275(35):27100-9.