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Hideyuki Hyogo

Research Profile

Disorders

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Chemicals & Drugs

Anatomy

Physiology

Lipid Metabolism

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Japan

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Publications

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Yoko Kominami; Daiki Miki; Daisuke Miyaki; Eisuke Murakami; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Tamito Sasaki; Masahiro Serikawa; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Masataka Tsuge; Nobuhiko Hiraga; Ken Hiramatsu; Yoji Honda; Hideyuki Hyogo; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Hiroshi Aikata; Kazuaki Chayama
[A case of clonorchiasis complicated with the expansion of liver cyst].
Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease.
Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance.

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All Publications

2013: Yoko Kominami; Daiki Miki; Daisuke Miyaki; Eisuke Murakami; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Tamito Sasaki; Masahiro Serikawa; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Masataka Tsuge; Nobuhiko Hiraga; Ken Hiramatsu; Yoji Honda; Hideyuki Hyogo; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Hiroshi Aikata; Kazuaki Chayama
[A case of clonorchiasis complicated with the expansion of liver cyst].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2013;110(3):456-64.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease.
Clinical biochemistry 2012;45(18):1554-7.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012;44(11):935-9.
2012: Takashi Nakahara; Shoichi Takahashi; Hiroshi Aikata; Koji Arihiro; Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Kazuaki Chayama
Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(11):1065-72.
2012: Koichi Kagawa; Yoshiiku Kawakami; Tomokazu Kawaoka; Daisuke Miyaki; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Hayato Sanetou; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Hiroshi Aikata; Koji Arihiro; Akira Hiramatsu; Youji Honda; Hideyuki Hyogo; Kazuaki Chayama
[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(8):1401-8.
2012: Mayu Ohnishi; Shoichi Takahashi; Shinji Tanaka; Masataka Tsuge; Yizhou Zhang; Hiromi Abe; Koji Arihiro; C Nelson Hayes; Nobuhiko Hiraga; Hideyuki Hyogo; Michio Imamura; Yuki Kimura; Tomohiko Kohno; Daiki Miki; Hidenori Ochi; Kazuaki Chayama
IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.
Journal of gastroenterology 2012;47(7):834-44.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012;44(6):492-6.
2012: Yuko Nagaoki; Takashi Nakahara; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Hiroshi Aikata; Akira Hiramatsu; Yoji Honda; Hideyuki Hyogo; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Daisuke Miyaki; Noriaki Naeshiro; Kazuaki Chayama
Recent trend of clinical features in patients with hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(4):368-75.
2012: Aya Kanbara; Yoshisuke Miura; Kazuaki Chayama; Hideyuki Hyogo; Issei Seyama
Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid.
Nutrition journal 2012;11():39.
2012: Yoshio Sumida; Yasuaki Suzuki; Masato Yoneda; Toshikazu Yoshikawa; Noriaki Aoki; Kazuaki Chayama; Yuichiro Eguchi; Hideki Fujii; Kazuma Fujimoto; Koji Fujita; Hideyuki Hyogo; Yoshito Itoh; Kazuyuki Kanemasa; Norifumi Kawada; Yutaka Kohgo; Takeshi Okanoue; Masafumi Ono; Toshiji Saibara
Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population.
BMC gastroenterology 2012;12():2.
2011: Masato Yoneda; Toshikazu Yoshikawa; Noriaki Aoki; Kazuaki Chayama; Yuichiro Eguchi; Hideki Fujii; Kazuma Fujimoto; Hideyuki Hyogo; Kento Imajo; Yoshito Itoh; Kazuyuki Kanemasa; Norifumi Kawada; Yutaka Kohgo; Takeshi Okanoue; Masafumi Ono; Toshiji Saibara; Yoshio Sumida; Yasuaki Suzuki
Platelet count for predicting fibrosis in nonalcoholic fatty liver disease.
Journal of gastroenterology 2011;46(11):1300-6.
2011: Motoki Inoue; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Kazuhiko Igarashi; Kazuaki Chayama
Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model.
Journal of clinical biochemistry and nutrition 2011;48(2):161-6.
2011: Yuki Kimura; Hideyuki Hyogo; Tomokazu Ishitobi; Yoshitaka Nabeshima; Koji Arihiro; Kazuaki Chayama
Postprandial insulin secretion pattern is associated with histological severity in non-alcoholic fatty liver disease patients without prior known diabetes mellitus.
Journal of gastroenterology and hepatology 2011;26(3):517-22.
2011: Yoshio Sumida; Masato Yoneda; Hideyuki Hyogo; Kanji Yamaguchi; Masafumi Ono; Hideki Fujii; Yuichiro Eguchi; Yasuaki Suzuki; Shunsuke Imai; Kazuyuki Kanemasa; Koji Fujita; Kazuaki Chayama; Kohichiroh Yasui; Toshiji Saibara; Norifumi Kawada; Kazuma Fujimoto; Yutaka Kohgo; Takeshi Okanoue
A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease.
Journal of gastroenterology 2011;46(2):257-68.
2010: Yuki Kimura; Hideyuki Hyogo; Sho-ichi Yamagishi; Masayoshi Takeuchi; Tomokazu Ishitobi; Yoshitaka Nabeshima; Koji Arihiro; Kazuaki Chayama
Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH.
Journal of gastroenterology 2010;45(7):750-7.
2010: Tamar H Taddei; James Dziura; S Chen; Ruhua Yang; Hideyuki Hyogo; Cameron Sullards; David E Cohen; Gregory Pastores; Pramod K Mistry
High incidence of cholesterol gallstone disease in type 1 Gaucher disease: characterizing the biliary phenotype of type 1 Gaucher disease.
Journal of inherited metabolic disease 2010;33(3):291-300.
2009: Yoshitaka Nabeshima; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Kazuaki Chayama
Deletion of angiotensin II type I receptor reduces hepatic steatosis.
Journal of hepatology 2009;50(6):1226-35.
2008: Hideyuki Hyogo; Susumu Tazuma; Koji Arihiro; Keiko Iwamoto; Yoshitaka Nabeshima; Motoki Inoue; Tomokazu Ishitobi; Michihiro Nonaka; Kazuaki Chayama
Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia.
Metabolism: clinical and experimental 2008;57(12):1711-8.
2008: Michihiro Nonaka; Susumu Tazuma; Hideyuki Hyogo; Keishi Kanno; Kazuaki Chayama
Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand.
Journal of gastroenterology and hepatology 2008;23(7 Pt 2):e198-206.
2008: Hideyuki Hyogo; Sho-ichi Yamagishi
Advanced glycation end products (AGEs) and their involvement in liver disease.
Current pharmaceutical design 2008;14(10):969-72.
2008: Keiko Iwamoto; Keishi Kanno; Hideyuki Hyogo; Sho-ichi Yamagishi; Masayoshi Takeuchi; Susumu Tazuma; Kazuaki Chayama
Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells.
Journal of gastroenterology 2008;43(4):298-304.
2007: Hideyuki Hyogo; Susumu Tazuma
[Disturbance of lipid metabolism in patients with liver diseases].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 7():412-6.
2007: Hideyuki Hyogo; Sho-ichi Yamagishi; Keiko Iwamoto; Koji Arihiro; Masayoshi Takeuchi; Takashi Sato; Hidenori Ochi; Michihiro Nonaka; Yoshitaka Nabeshima; Motoki Inoue; Tomokazu Ishitobi; Kazuaki Chayama; Susumu Tazuma
Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis.
Journal of gastroenterology and hepatology 2007;22(7):1112-9.
2006: Toshiya Kobuke; Susumu Tazuma; Hideyuki Hyogo; Kazuaki Chayama
A Ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: potential molecular targeting strategy for cholangioma.
Digestive diseases and sciences 2006;51(9):1650-7.
2006: Yoshitaka Nabeshima; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Masaru Iwai; Masatsugu Horiuchi; Kazuaki Chayama
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis.
Biochemical and biophysical research communications 2006;346(3):658-64.
2005: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage.
Free radical biology & medicine 2005;39(11):1418-27.
2005: Yoshihiro Numata; Susumu Tazuma; Yoshitaka Ueno; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis.
Digestive diseases and sciences 2005;50(10):1844-51.
2005: Tomohiko Shimatani; Masaki Inoue; Keiko Iwamoto; Hideyuki Hyogo; Michiya Yokozaki; Toshinari Saeki; Susumu Tazuma; Yoko Horikawa
Prevalence of Helicobacter pylori infection, endoscopic gastric findings and dyspeptic symptoms among a young Japanese population born in the 1970s.
Journal of gastroenterology and hepatology 2005;20(9):1352-7.
2005: Atsushi Yamaguchi; Susumu Tazuma; Tomoji Nishioka; Waka Ohishi; Hideyuki Hyogo; Shuichi Nomura; Kazuaki Chayama
Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver.
Digestive diseases and sciences 2005;50(7):1361-71.
2005: Tomohiko Shimatani; Masaki Inoue; Keiko Iwamoto; Hideyuki Hyogo; Michiya Yokozaki; Toshinari Saeki; Susumu Tazuma; Yoko Horikawa; Nobue Harada
Gastric acidity in patients with follicular gastritis is significantly reduced, but can be normalized after eradication for Helicobacter pylori.
Helicobacter 2005;10(3):256-65.
2005: Keishi Kanno; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression.
Digestive diseases and sciences 2005;50(5):942-8.
2005: Suheeta Roy; Hideyuki Hyogo; Suresh K Yadav; Michele K Wu; Linda Jelicks; Joseph Locker; Philippe G Frank; Michael P Lisanti; David L Silver; David E Cohen
A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse.
Hepatology (Baltimore, Md.) 2005;41(4):887-95.
2005: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists.
Digestive diseases and sciences 2005;50(3):514-24.
2005: Michele K Wu; Hideyuki Hyogo; Suresh K Yadav; Phyllis M Novikoff; David E Cohen
Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice.
Journal of lipid research 2005;46(3):422-31.
2005: Tomoji Nishioka; Hideyuki Hyogo; Yoshihiro Numata; Atsushi Yamaguchi; Toshiya Kobuke; Daisuke Komichi; Michihiro Nonaka; Motoki Inoue; Yoshitaka Nabeshima; Mami Ogi; Keiko Iwamoto; Tomokazu Ishitobi; Takeyoshi Ajima; Kazuaki Chayama; Susumu Tazuma
A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion.
Journal of atherosclerosis and thrombosis 2005;12(4):211-7.
2005: Sandrine Dubrac; Steven R Lear; Meenakshisundaram Ananthanarayanan; Natarajan Balasubramaniyan; Jaya Bollineni; Sarah Shefer; Hideyuki Hyogo; David E Cohen; Patricia J Blanche; Ronald M Krauss; Ashok K Batta; Gerald Salen; Frederick J Suchy; Nobuyo Maeda; Sandra K Erickson
Role of CYP27A in cholesterol and bile acid metabolism.
Journal of lipid research 2005;46(1):76-85.
2003: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Mizuho Une; Kazuaki Chayama
Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes.
Digestive diseases and sciences 2003;48(12):2315-22.
2003: Hideyuki Hyogo; Suheeta Roy; David E Cohen
Restoration of gallstone susceptibility by leptin in C57BL/6J ob/ob mice.
Journal of lipid research 2003;44(6):1232-40.
2003: Sandra K Erickson; Steven R Lear; Sean Deane; Sandrine Dubrac; Sandra L Huling; Lien Nguyen; Jaya Bollineni; Sarah Shefer; Hideyuki Hyogo; David E Cohen; Benjamin L Shneider; Ephraim Sehayek; Meenakshisundaram Ananthanarayanan; Natarajan Balasubramaniyan; Frederick J Suchy; Ashok K Batta; Gerald Salen
Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice.
Journal of lipid research 2003;44(5):1001-9.
2003: Ludwig Amigo; Silvana Zanlungo; Juan Miquel; Jane M Glick; Hideyuki Hyogo; David E Cohen; Attilio Rigotti; Flavio Nervi
Hepatic overexpression of sterol carrier protein-2 inhibits VLDL production and reciprocally enhances biliary lipid secretion.
Journal of lipid research 2003;44(2):399-407.
2003: Susumu Tazuma; Tomoji Nishioka; Hidenori Ochi; Hideyuki Hyogo; Yasushi Sunami; Kuniharu Nakai; Kazuhiko Tsuboi; Yasumasa Asamoto; Minoru Sakomoto; Yoshihiro Numata; Keishi Kanno; Atsushi Yamaguchi; Toshiya Kobuke; Daisuke Komichi; Yoshihiro Nonaka; Kazuaki Chayama
Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy.
Journal of gastroenterology and hepatology 2003;18(2):157-61.
2002: William Schubert; Philippe G Frank; Scott E Woodman; Hideyuki Hyogo; David E Cohen; Chi-Wing Chow; Michael P Lisanti
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice.
The Journal of biological chemistry 2002;277(42):40091-8.
2002: Hideyuki Hyogo; Suheeta Roy; Beverly Paigen; David E Cohen
Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts.
The Journal of biological chemistry 2002;277(37):34117-24.
2002: Hideyuki Hyogo; Susumu Tazuma; David E Cohen
Cholesterol gallstones.
Current opinion in gastroenterology 2002;18(3):366-71.
2001: Hideyuki Hyogo; Susumu Tazuma; Tomoji Nishioka; Hidenori Ochi; Atsushi Yamaguchi; Yoshihiro Numata; Keishi Kanno; Minoru Sakomoto; Yasumasa Asamoto; Kazuhiko Tsuboi; Kuniharu Nakai; S Yasumiba; Yasushi Sunami; Goro Kajiyama
Phospholipid alterations in hepatocyte membranes and transporter protein changes in cholestatic rat model.
Digestive diseases and sciences 2001;46(10):2089-97.
2000: Hidenori Ochi; Susumu Tazuma; T Kajihara; Hideyuki Hyogo; Yasushi Sunami; S Yasumiba; Kuniharu Nakai; Kazuhiko Tsuboi; Yasumasa Asamoto; Minoru Sakomoto; Goro Kajiyama
Factors affecting gallstone recurrence after successful extracorporeal shock wave lithotripsy.
Journal of clinical gastroenterology 2000;31(3):230-2.
2000: Hideyuki Hyogo; Susumu Tazuma; Goro Kajiyama
Biliary excretory function is regulated by canalicular membrane fluidity associated with phospholipid fatty acyl chains in the bilayer: implications for the pathophysiology of cholestasis.
Journal of gastroenterology and hepatology 2000;15(8):887-94.
2000: Y Hattori; Susumu Tazuma; G Yamashita; Hidenori Ochi; Yasushi Sunami; Tomoji Nishioka; Hideyuki Hyogo; S Yasumiba; T Kajihara; Kuniharu Nakai; Kazuhiko Tsuboi; Yasumasa Asamoto; Minoru Sakomoto; Goro Kajiyama
Role of phospholipase A2 in cholesterol gallstone formation is associated with biliary phospholipid species selection at the site of hepatic excretion: indirect evidence.
Digestive diseases and sciences 2000;45(7):1413-21.
1999: Hideyuki Hyogo; Susumu Tazuma; Goro Kajiyama
Transcytotic vesicle fusion is reduced in cholestatic rats: redistribution of phospholipids in the canalicular membrane.
Digestive diseases and sciences 1999;44(8):1662-8.
1998: Susumu Tazuma; Goro Kajiyama; T Mizuno; G Yamashita; H Miura; T Kajihara; Y Hattori; H Miyake; Tomoji Nishioka; Hideyuki Hyogo; Yasushi Sunami; S Yasumiba; Hidenori Ochi; T Matsumoto; A Abe; K Adachi; F Omata; F Ueno; F Sugata; S Ohguri; H Shibata; S Kokubu
A combination therapy with simvastatin and ursodeoxycholic acid is more effective for cholesterol gallstone dissolution than is ursodeoxycholic acid monotherapy.
Journal of clinical gastroenterology 1998;26(4):287-91.
1998: Susumu Tazuma; G Yamashita; Hidenori Ochi; H Miura; T Kajihara; Y Hattori; H Miyake; Tomoji Nishioka; Hideyuki Hyogo; Yasushi Sunami; S Yasumiba; Goro Kajiyama
Effects of cerivastatin sodium, a new HMG-CoA reductase inhibitor, on biliary lipid metabolism in patients with hypercholesterolemia.
Clinical therapeutics 1998;20(3):477-85.
1997: Susumu Tazuma; H Miura; N Hirano; Y Hattori; T Kajihara; D Tsuchimoto; H Miyake; Tomoji Nishioka; Hideyuki Hyogo; S Nakao; G Yamashita; Goro Kajiyama
A quantitative assessment of serum chylomicron by light scattering intensity: application to the intestinal fat absorption test.
Journal of gastroenterology and hepatology 1997;12(11):713-8.