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Hideo Iba

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Takanobu Tagawa; Takeshi Haraguchi; Hiroaki Hiramatsu; Ken-Ichi Inada; Kazuyoshi Kobayashi; Kouhei Sakurai; Hideo Iba
Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumour cells.
Aya Ishizaka; Kazuyoshi Kobayashi; Taketoshi Mizutani; Kouhei Sakurai; Toshio Tando; Toshinobu Fujiwara; Hideo Iba
Double plant homeodomain (PHD) finger proteins DPF3a and -3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF-κB RelA/p50 heterodimer.
Takeshi Haraguchi; Haruo Nakano; Tokimitsu Ohki; Takanobu Tagawa; Yoshihito Ueno; Tetsuo Yoshida; Hideo Iba
A potent 2'-O-methylated RNA-based microRNA inhibitor with unique secondary structures.

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2012: Takanobu Tagawa; Takeshi Haraguchi; Hiroaki Hiramatsu; Ken-Ichi Inada; Kazuyoshi Kobayashi; Kouhei Sakurai; Hideo Iba
Multiple microRNAs induced by Cdx1 suppress Cdx2 in human colorectal tumour cells.
The Biochemical journal 2012;447(3):449-55.
2012: Aya Ishizaka; Kazuyoshi Kobayashi; Taketoshi Mizutani; Kouhei Sakurai; Toshio Tando; Toshinobu Fujiwara; Hideo Iba
Double plant homeodomain (PHD) finger proteins DPF3a and -3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF-κB RelA/p50 heterodimer.
The Journal of biological chemistry 2012;287(15):11924-33.
2012: Takeshi Haraguchi; Haruo Nakano; Tokimitsu Ohki; Takanobu Tagawa; Yoshihito Ueno; Tetsuo Yoshida; Hideo Iba
A potent 2'-O-methylated RNA-based microRNA inhibitor with unique secondary structures.
Nucleic acids research 2012;40(8):e58.
2012: Yukiko Kurashima; Sachiko Nakajima; Tomonori Nochi; Shintaro Sato; Hiroko Tsutsui; Takeaki Amiya; Kumiko Fujisawa; Takeshi Haraguchi; Hideo Iba; Hideki Iijima; Masato Kubo; Jun Kunisawa; Hiroshi Kiyono
Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.
Nature communications 2012;3():1034.
2011: Mina Hikichi; Minoru Kidokoro; Takeshi Haraguchi; Hideo Iba; Hisatoshi Shida; Hideaki Tahara; Takafumi Nakamura
MicroRNA regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(6):1107-15.
2009: Taketoshi Mizutani; Aya Ishizaka; Mariko Tomizawa; Takuya Okazaki; Nobutake Yamamichi; Ai Kawana-Tachikawa; Aikichi Iwamoto; Hideo Iba
Loss of the Brm-type SWI/SNF chromatin remodeling complex is a strong barrier to the Tat-independent transcriptional elongation of human immunodeficiency virus type 1 transcripts.
Journal of virology 2009;83(22):11569-80.
2009: Nobutake Yamamichi; Ryoichi Shimomura; Ken-ichi Inada; Kouhei Sakurai; Takeshi Haraguchi; Yuka Ozaki; Shuji Fujita; Taketoshi Mizutani; Chihiro Furukawa; Mitsuhiro Fujishiro; Masao Ichinose; Kazuya Shiogama; Yutaka Tsutsumi; Masao Omata; Hideo Iba
Locked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4009-16.
2009: Nobutake Yamamichi; Ken-ichi Inada; Chihiro Furukawa; Kouhei Sakurai; Toshio Tando; Aya Ishizaka; Takeshi Haraguchi; Taketoshi Mizutani; Mitsuhiro Fujishiro; Ryoichi Shimomura; Masashi Oka; Masao Ichinose; Yutaka Tsutsumi; Masao Omata; Hideo Iba
Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells.
Experimental cell research 2009;315(10):1779-89.
2009: Takeshi Haraguchi; Yuka Ozaki; Hideo Iba
Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells.
Nucleic acids research 2009;37(6):e43.
2008: Shuji Fujita; Taiji Ito; Taketoshi Mizutani; Shigeru Minoguchi; Nobutake Yamamichi; Kouhei Sakurai; Hideo Iba
miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism.
Journal of molecular biology 2008;378(3):492-504.
2008: Shigeru Minoguchi; Hideo Iba
Instability of retroviral DNA methylation in embryonic stem cells.
Stem cells (Dayton, Ohio) 2008;26(5):1166-73.
2008: Taiji Ito; Hirotaka Watanabe; Nobutake Yamamichi; Shunsuke Kondo; Toshio Tando; Takeshi Haraguchi; Taketoshi Mizutani; Kouhei Sakurai; Shuji Fujita; Tomonori Izumi; Toshiaki Isobe; Hideo Iba
Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb).
The Biochemical journal 2008;411(1):201-9.
2008: Shuji Fujita; Hideo Iba
Putative promoter regions of miRNA genes involved in evolutionarily conserved regulatory systems among vertebrates.
Bioinformatics (Oxford, England) 2008;24(3):303-8.
2007: Nobutake Yamamichi; Ken-ichi Inada; Masao Ichinose; Mitsue Yamamichi-Nishina; Taketoshi Mizutani; Hirotaka Watanabe; Kazuya Shiogama; Midori Fujishiro; Takuya Okazaki; Naoya Yahagi; Takeshi Haraguchi; Shuji Fujita; Yutaka Tsutsumi; Masao Omata; Hideo Iba
Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state.
Cancer research 2007;67(22):10727-35.
2007: Takeshi Haraguchi; Taketoshi Mizutani; Nobutake Yamamichi; Taiji Ito; Shigeru Minoguchi; Hideo Iba
SiRNAs do not induce RNA-dependent transcriptional silencing of retrovirus in human cells.
FEBS letters 2007;581(25):4949-54.
2006: Yasutaka Wakabayashi; Makiko Kobayashi; Sachiko Akashi-Takamura; Natsuko Tanimura; Kazunori Konno; Koichiro Takahashi; Takashi Ishii; Taketoshi Mizutani; Hideo Iba; Taku Kouro; Satoshi Takaki; Kiyoshi Takatsu; Yoshiya Oda; Yasushi Ishihama; Shin-ichiroh Saitoh; Kensuke Miyake
A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1772-9.
2006: Naohiko Hasegawa; Hiroyuki Kawaguchi; Akio Hirachi; Katsuhiro Takeda; Noriyoshi Mizuno; Masahiro Nishimura; Chika Koike; Koichiro Tsuji; Hideo Iba; Yukio Kato; Hidemi Kurihara
Behavior of transplanted bone marrow-derived mesenchymal stem cells in periodontal defects.
Journal of periodontology 2006;77(6):1003-7.
2006: Hirotaka Watanabe; Taketoshi Mizutani; Takeshi Haraguchi; Nobutake Yamamichi; Shigeru Minoguchi; Mitsue Yamamichi-Nishina; Naoki Mori; Takashi Kameda; T Sugiyama; Hideo Iba
SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines.
Oncogene 2006;25(3):470-9.
2005: Nobutake Yamamichi; Mitsue Yamamichi-Nishina; Taketoshi Mizutani; Hirotaka Watanabe; Shigeru Minoguchi; Nao Kobayashi; Satoko Kimura; Taiji Ito; Naoya Yahagi; Masao Ichinose; Masao Omata; Hideo Iba
The Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential.
Oncogene 2005;24(35):5471-81.
2004: Masayuki Hirano; Yuji Kikuchi; Sazuku Nisitani; Akiko Yamaguchi; Atsushi Satoh; Taiji Ito; Hideo Iba; Kiyoshi Takatsu
Bruton's tyrosine kinase (Btk) enhances transcriptional co-activation activity of BAM11, a Btk-associated molecule of a subunit of SWI/SNF complexes.
International immunology 2004;16(5):747-57.
2003: Hideo Iba; Mitsue Yamamichi-Nishina; Taketoshi Mizutani
[Retroviral gene silencing--virology as a field for elucidating molecular mechanisms of epigenetics].
Uirusu 2003;53(2):133-9.
2003: Kimiko Fukuda; Takashi Kameda; Kanako Saitoh; Hideo Iba; Sadao Yasugi
Down-regulation of endodermal Shh is required for gland formation in chicken stomach.
Mechanisms of development 2003;120(7):801-9.
2003: Hideo Iba; Taketoshi Mizutani; Taiji Ito
SWI/SNF chromatin remodelling complex and retroviral gene silencing.
Reviews in medical virology 2003;13(2):99-110.
2003: Mitsue Yamamichi-Nishina; Taiji Ito; Taketoshi Mizutani; Nobutake Yamamichi; Hirotaka Watanabe; Hideo Iba
SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.
The Journal of biological chemistry 2003;278(9):7422-30.
2003: Yasuhito Shimizu; Nobutake Yamamichi; K Saitoh; A Watanabe; Taiji Ito; Mitsue Yamamichi-Nishina; M Mizutani; Naoya Yahagi; Takahiro Suzuki; C Sasakawa; Sadao Yasugi; Masao Ichinose; Hideo Iba
Kinetics of v-src-induced epithelial-mesenchymal transition in developing glandular stomach.
Oncogene 2003;22(6):884-93.
2002: Taketoshi Mizutani; Taiji Ito; Mitsue Nishina; Nobutake Yamamichi; Akiko Watanabe; Hideo Iba
Maintenance of integrated proviral gene expression requires Brm, a catalytic subunit of SWI/SNF complex.
The Journal of biological chemistry 2002;277(18):15859-64.
2002: Chika Koike; Taketoshi Mizutani; Taiji Ito; Yasuhito Shimizu; Nobutake Yamamichi; Takashi Kameda; Eiji Michimukai; Naoya Kitamura; Tetsuji Okamoto; Hideo Iba
Introduction of wild-type patched gene suppresses the oncogenic potential of human squamous cell carcinoma cell lines including A431.
Oncogene 2002;21(17):2670-8.
2001: Taiji Ito; Mai Yamauchi; M Nishina; Nobutake Yamamichi; Taketoshi Mizutani; Michio Ui; Makoto Murakami; Hideo Iba
Identification of SWI.SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers.
The Journal of biological chemistry 2001;276(4):2852-7.
2000: Michio Ui; Taketoshi Mizutani; M Takada; T Arai; Taiji Ito; Makoto Murakami; Chika Koike; Tomomi Watanabe; K Yoshimatsu; Hideo Iba
Endogenous AP-1 levels necessary for oncogenic activity are higher than those sufficient to support normal growth.
Biochemical and biophysical research communications 2000;278(1):97-105.
2000: Takashi Kameda; Chika Koike; K Saitoh; A Kuroiwa; Hideo Iba
Analysis of cartilage maturation using micromass cultures of primary chondrocytes.
Development, growth & differentiation 2000;42(3):229-36.
2000: Hideo Iba
Gene transfer into chicken embryos by retrovirus vectors.
Development, growth & differentiation 2000;42(3):213-8.
2000: Kimiko Fukuda; N Sakamoto; Takanori Narita; K Saitoh; Takashi Kameda; Hideo Iba; Sadao Yasugi
Application of efficient and specific gene transfer systems and organ culture techniques for the elucidation of mechanisms of epithelial-mesenchymal interaction in the developing gut.
Development, growth & differentiation 2000;42(3):207-11.
2000: A Sukegawa; T Narita; T Kameda; K Saitoh; Tsutomu Nohno; Hideo Iba; Sadao Yasugi; K Fukuda
The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium.
Development (Cambridge, England) 2000;127(9):1971-80.
2000: Takanori Narita; K Saitoh; Takashi Kameda; A Kuroiwa; M Mizutani; Chika Koike; Hideo Iba; Sadao Yasugi
BMPs are necessary for stomach gland formation in the chicken embryo: a study using virally induced BMP-2 and Noggin expression.
Development (Cambridge, England) 2000;127(5):981-8.
1999: T Arai; M Takada; M Ui; Hideo Iba
Dose-dependent transduction of vesicular stomatitis virus G protein-pseudotyped retrovirus vector into human solid tumor cell lines and murine fibroblasts.
Virology 1999;260(1):109-15.
1999: Makoto Murakami; Michio Ui; Hideo Iba
Fra-2-positive autoregulatory loop triggered by mitogen-activated protein kinase (MAPK) and Fra-2 phosphorylation sites by MAPK.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(5):333-42.
1999: Takashi Kameda; Chika Koike; K Saitoh; A Kuroiwa; Hideo Iba
Developmental patterning in chondrocytic cultures by morphogenic gradients: BMP induces expression of indian hedgehog and noggin.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(3):175-84.
1998: Taiji Ito; Y Kabuyama; S Okazaki; T Kameda; Makoto Murakami; Hideo Iba
Unstable retrovirus mutants with acquired transforming activity: rapid changes in the number of repeats of a specific junD polynucleotide segment.
Nucleic acids research 1998;26(21):4868-73.
1998: S Okazaki; Taiji Ito; Michio Ui; Tomomi Watanabe; K Yoshimatsu; Hideo Iba
Two proteins translated by alternative usage of initiation codons in mRNA encoding a JunD transcriptional regulator.
Biochemical and biophysical research communications 1998;250(2):347-53.
1998: Michio Ui; Mami Sonobe; Taiji Ito; Makoto Murakami; S Okazaki; M Takada; Takehito Sato; Hideo Iba
Biochemical and functional analysis of highly phosphorylated forms of c-Jun protein.
FEBS letters 1998;429(3):289-94.
1998: Ken Matsumoto; K Saitoh; Chika Koike; Takanori Narita; Sadao Yasugi; Hideo Iba
Differential expression of fos and jun family members in the developing chicken gastrointestinal tract.
Oncogene 1998;16(12):1611-6.
1998: T Kameda; Hideo Iba
Suppression of cellular transformation by glucocorticoid receptor mutants.
Cancer research 1998;58(5):867-70.
1998: T Arai; K Matsumoto; K Saitoh; M Ui; Taiji Ito; M Murakami; Yumi Kanegae; Izumu Saito; F L Cosset; Y Takeuchi; Hideo Iba
A new system for stringent, high-titer vesicular stomatitis virus G protein-pseudotyped retrovirus vector induction by introduction of Cre recombinase into stable prepackaging cell lines.
Journal of virology 1998;72(2):1115-21.
1997: Makoto Murakami; Hidenori Watanabe; Yuichi Niikura; T Kameda; K Saitoh; M Yamamoto; Y Yokouchi; A Kuroiwa; K Mizumoto; Hideo Iba
High-level expression of exogenous genes by replication-competent retrovirus vectors with an internal ribosomal entry site.
Gene 1997;202(1-2):23-9.
1997: Mariko Kobayashi; Satoshi Nagata; Yoshihiro Kita; N Nakatsu; Sayoko Ihara; Kozo Kaibuchi; S Kuroda; Michio Ui; Hideo Iba; H Konishi; U Kikkawa; I Saitoh; Yasuhisa Fukui
Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system.
The Journal of biological chemistry 1997;272(26):16089-92.
1997: Makoto Murakami; Mami Sonobe; Michio Ui; Y Kabuyama; Hidenori Watanabe; T Wada; H Handa; Hideo Iba
Phosphorylation and high level expression of Fra-2 in v-src transformed cells: a pathway of activation of endogenous AP-1.
Oncogene 1997;14(20):2435-44.
1997: T Kameda; H Watanabe; Hideo Iba
C-Jun and JunD suppress maturation of chondrocytes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(5):495-503.
1997: Hidenori Watanabe; K Saitoh; T Kameda; Makoto Murakami; Yuichi Niikura; S Okazaki; Y Morishita; S Mori; Y Yokouchi; A Kuroiwa; Hideo Iba
Chondrocytes as a specific target of ectopic Fos expression in early development.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3994-9.
1995: M H Sonobe; T Yoshida; Makoto Murakami; T Kameda; Hideo Iba
fra-2 promoter can respond to serum-stimulation through AP-1 complexes.
Oncogene 1995;10(4):689-96.
1994: Victoria C Foletta; M H Sonobe; T Suzuki; T Endo; Hideo Iba; D R Cohen
Cloning and characterisation of the mouse fra-2 gene.
Oncogene 1994;9(11):3305-11.
1994: T Suzuki; Makoto Murakami; N Onai; E Fukuda; Yuichi Hashimoto; M H Sonobe; T Kameda; M Ichinose; K Miki; Hideo Iba
Analysis of AP-1 function in cellular transformation pathways.
Journal of virology 1994;68(6):3527-35.
1993: T Kameda; A Akahori; M H Sonobe; T Suzuki; T Endo; Hideo Iba
JunD mutants with spontaneously acquired transforming potential have enhanced transactivating activity in combination with Fra-2.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9369-73.
1993: T Yoshida; T Suzuki; H Sato; Hiroshi Nishina; Hideo Iba
Analysis of fra-2 gene expression.
Nucleic acids research 1993;21(11):2715-21.
1993: Hiroyuki Okuno; A Akahori; H Sato; S Xanthoudakis; T Curran; Hideo Iba
Escape from redox regulation enhances the transforming activity of Fos.
Oncogene 1993;8(3):695-701.
1991: T Suzuki; Hiroyuki Okuno; T Yoshida; T Endo; Hiroshi Nishina; Hideo Iba
Difference in transcriptional regulatory function between c-Fos and Fra-2.
Nucleic acids research 1991;19(20):5537-42.
1991: Hiroyuki Okuno; T Suzuki; T Yoshida; Y Hashimoto; T Curran; Hideo Iba
Inhibition of jun transformation by a mutated fos gene: design of an anti-oncogene.
Oncogene 1991;6(9):1491-7.
1991: T Yoshida; H Sato; Hideo Iba
Transcription of fra-2 mRNA and phosphorylation of Fra-2 protein are stimulated by serum.
Biochemical and biophysical research communications 1991;174(2):934-9.
1991: T Suzuki; Yuichi Hashimoto; Hiroyuki Okuno; H Sato; Hiroshi Nishina; Hideo Iba
High-level expression of human c-jun gene causes cellular transformation of chicken embryo fibroblasts.
Japanese journal of cancer research : Gann 1991;82(1):58-64.
1990: H Nishina; H Sato; T Suzuki; M Sato; Hideo Iba
Isolation and characterization of fra-2, an additional member of the fos gene family.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(9):3619-23.
1989: T Yoshida; Y Shindo; K Ohta; Hideo Iba
Identification of a small region of the v-fos gene product that is sufficient for transforming potential and growth-stimulating activity.
Oncogene research 1989;5(2):79-89.
1988: Hideo Iba; Y Shindo; H Nishina; T Yoshida
Transforming potential and growth stimulating activity of the v-fos and c-fos genes carried by avian retrovirus vectors.
Oncogene research 1988;2(2):121-33.
1987: K T Fujiwara; K Ashida; H Nishina; Hideo Iba; N Miyajima; M Nishizawa; S Kawai
The chicken c-fos gene: cloning and nucleotide sequence analysis.
Journal of virology 1987;61(12):4012-8.