FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

François Ichas

Research Profile

Chemicals & Drugs

Anatomy

Physiology

Signal Transduction

Concepts & Ideas

Co-author Network

Publications

TOP 3
Stéphane Pédeboscq; Christophe Rey; Francesca De Giorgi; Françoise Casadebaig; Arnaud Gissot; Denis Gravier; Geneviève Hou; François Ichas; Lydia Lartigue; Jean-Paul Pometan
Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines.
Céline Auzanneau; Francesca De Giorgi; Denis Deffieux; Assia Elkaoukabi-Chaibi; François Ichas; Rémi Jacquet; Danièle Montaudon; Laurent Pouységu; Stéphane Puyo; Stéphane Quideau; Philippe Pourquier
The polyphenolic ellagitannin vescalagin acts as a preferential catalytic inhibitor of the α isoform of human DNA topoisomerase II.
Stéphane Pédeboscq; Muriel Petit; Christophe Rey; Francesca De Giorgi; Catherine Harpey; François Ichas; Lydia Lartigue
Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein kinase inhibitors in vitro.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of François Ichas (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Stéphane Pédeboscq; Christophe Rey; Francesca De Giorgi; Françoise Casadebaig; Arnaud Gissot; Denis Gravier; Geneviève Hou; François Ichas; Lydia Lartigue; Jean-Paul Pometan
Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines.
Bioorganic & medicinal chemistry 2012;20(22):6724-31.
2012: Céline Auzanneau; Francesca De Giorgi; Denis Deffieux; Assia Elkaoukabi-Chaibi; François Ichas; Rémi Jacquet; Danièle Montaudon; Laurent Pouységu; Stéphane Puyo; Stéphane Quideau; Philippe Pourquier
The polyphenolic ellagitannin vescalagin acts as a preferential catalytic inhibitor of the α isoform of human DNA topoisomerase II.
Molecular pharmacology 2012;82(1):134-41.
2012: Stéphane Pédeboscq; Muriel Petit; Christophe Rey; Francesca De Giorgi; Catherine Harpey; François Ichas; Lydia Lartigue
Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein kinase inhibitors in vitro.
PloS one 2012;7(5):e36811.
2011: Isabelle Soubeyran; Isabelle Mahouche; Aude Grigoletto; Thierry Leste-Lasserre; Guillaume Drutel; Christophe Rey; Stephane Pedeboscq; France Blanchard; Veronique Brouste; Jean-Christophe Sabourin; Yves Bécouarn; Josy Reiffers; François Ichas; Francesca De Giorgi
Tissue microarray cytometry reveals positive impact of homeodomain interacting protein kinase 2 in colon cancer survival irrespective of p53 function.
The American journal of pathology 2011;178(5):1986-98.
2010: Stéphane Pédeboscq; Denis Gravier; Françoise Casadebaig; Geneviève Hou; Arnaud Gissot; Francesca De Giorgi; François Ichas; Jean Cambar; Jean-Paul Pometan
Synthesis and study of antiproliferative activity of novel thienopyrimidines on glioblastoma cells.
European journal of medicinal chemistry 2010;45(6):2473-9.
2009: Laura Schembri; Marion Zanese; Gaelle Depierre-Plinet; Muriel Petit; Assia Elkaoukabi-Chaibi; Loic Tauzin; Cristina Florean; Lydia Lartigue; Chantal Medina; Christophe Rey; Francis Belloc; Josy Reiffers; François Ichas; Francesca De Giorgi
Recombinant differential anchorage probes that tower over the spatial dimension of intracellular signals for high content screening and analysis.
Analytical chemistry 2009;81(23):9590-8.
2009: Flora Tomasello; Angela Messina; Lydia Lartigue; Laura Schembri; Chantal Medina; Simona Reina; Didier Thoraval; Marc Crouzet; François Ichas; Vito De Pinto; Francesca De Giorgi
Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis.
Cell research 2009;19(12):1363-76.
2009: Stéphane Pédeboscq; Béatrice L'Azou; Isabelle Passagne; Francesca De Giorgi; François Ichas; Dominique Liguoro; Jean-Paul Pometan; Jean Cambar
Anticancer drugs exert differential apoptotic and cytotoxic effects on glioblastoma primary cultures with various EGFR and bcl-2 profiles.
Journal of experimental therapeutics & oncology 2009;8(2):105-16.
2008: Lydia Lartigue; Chantal Medina; Laura Schembri; Paul Chabert; Marion Zanese; Flora Tomasello; Renée Dalibart; Didier Thoraval; Marc Crouzet; François Ichas; Francesca De Giorgi
An intracellular wave of cytochrome c propagates and precedes Bax redistribution during apoptosis.
Journal of cell science 2008;121(Pt 21):3515-23.
2008: Cristina Florean; Enrico Zampese; Marion Zanese; Lucia Brunello; François Ichas; Francesca De Giorgi; Paola Pizzo
High content analysis of gamma-secretase activity reveals variable dominance of presenilin mutations linked to familial Alzheimer's disease.
Biochimica et biophysica acta 2008;1783(8):1551-60.
2008: Vincent Verbiest; Danièle Montaudon; Michel T Tautu; Joyce Moukarzel; Jean-Pierre Portail; Judith Markovits; Jacques Robert; François Ichas; Philippe Pourquier
Protein arginine (N)-methyl transferase 7 (PRMT7) as a potential target for the sensitization of tumor cells to camptothecins.
FEBS letters 2008;582(10):1483-9.
2008: Marie Bénéteau; Mathieu Pizon; Benjamin Chaigne-Delalande; Sophie Daburon; Patrick Moreau; Francesca De Giorgi; François Ichas; Amélie Rebillard; Marie-Thérèse Dimanche-Boitrel; Jean-Luc Taupin; Jean-François Moreau; Patrick Legembre
Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway.
Molecular cancer research : MCR 2008;6(4):604-13.
2008: Stéphane Pédeboscq; Béatrice L'Azou; Isabelle Passagne; Francesca De Giorgi; François Ichas; Jean-Paul Pometan; Jean Cambar
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
Journal of experimental therapeutics & oncology 2008;7(2):99-111.
2008: David Dupret; Jean-Michel Revest; Muriel Koehl; François Ichas; Francesca De Giorgi; Pierre Costet; Djoher Nora Abrous; Pier Vincenzo Piazza
Spatial relational memory requires hippocampal adult neurogenesis.
PloS one 2008;3(4):e1959.
2007: David Lasne; Gerhard A Blab; Francesca De Giorgi; François Ichas; Brahim Lounis; Laurent Cognet
Label-free optical imaging of mitochondria in live cells.
Optics express 2007;15(21):14184-93.
2007: Arnaud Jaubert; Guillaume Drutel; Thierry Leste-Lasserre; François Ichas; Laurence Bresson-Bepoldin
Tyrosine hydroxylase and dopamine transporter expression in lactotrophs from postlactating rats: involvement in dopamine-induced apoptosis.
Endocrinology 2007;148(6):2698-707.
2007: Laura Schembri; Renee Dalibart; Flora Tomasello; Patrick Legembre; François Ichas; Francesca De Giorgi
The HA tag is cleaved and loses immunoreactivity during apoptosis.
Nature methods 2007;4(2):107-8.
2006: Arnaud Jaubert; François Ichas; Laurence Bresson-Bepoldin
Signaling pathway involved in the pro-apoptotic effect of dopamine in the GH3 pituitary cell line.
Neuroendocrinology 2006;83(2):77-88.
2005: Patrick Legembre; Sophie Daburon; Patrick Moreau; François Ichas; Francesca De Giorgi; Jean-François Moreau; Jean-Luc Taupin
Amplification of Fas-mediated apoptosis in type II cells via microdomain recruitment.
Molecular and cellular biology 2005;25(15):6811-20.
2005: Naoual L Benali-Furet; MOUNIA CHAMI; Ludivine Houel; Francesca De Giorgi; Fabienne Vernejoul; David Lagorce; Louis Buscail; Ralf Bartenschlager; François Ichas; Rosario Rizzuto; Patrizia Paterlini-Bréchot
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion.
Oncogene 2005;24(31):4921-33.
2005: Laurent M Dejean; Sonia Martinez-Caballero; Liang Guo; Cynthia Hughes; Oscar Teijido; Thomas Ducret; François Ichas; Stanley J Korsmeyer; Bruno Antonsson; Elizabeth A Jonas; Kathleen W Kinnally
Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel.
Molecular biology of the cell 2005;16(5):2424-32.
2003: Vito De Pinto; Angelo Messina; Rosita Accardi; Rita Aiello; Francesca Guarino; Marianna Flora Tomasello; Massimo Tommasino; Gianluca Tasco; Rita Casadio; Roland Benz; Francesca De Giorgi; François Ichas; Mark Baker; Alfons Lawen
New functions of an old protein: the eukaryotic porin or voltage dependent anion selective channel (VDAC).
The Italian journal of biochemistry 2003;52(1):17-24.
2002: Jean Dessolin; Marie Schuler; Alice Quinart; Francesca De Giorgi; Leon Ghosez; François Ichas
Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?
European journal of pharmacology 2002;447(2-3):155-61.
2002: Francesca De Giorgi; Lydia Lartigue; Manuel K A Bauer; Alexis Schubert; Stefan Grimm; George T Hanson; S James Remington; Richard J Youle; François Ichas
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):607-9.
2000: Francesca De Giorgi; L Lartigue; François Ichas
Electrical coupling and plasticity of the mitochondrial network.
Cell calcium 2000;28(5-6):365-70.
1998: François Ichas; Jean-Pierre Mazat
From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state.
Biochimica et biophysica acta 1998;1366(1-2):33-50.
1998: LS Jouaville; François Ichas; Jean-Pierre Mazat
Modulation of cell calcium signals by mitochondria.
Molecular and cellular biochemistry 1998;184(1-2):371-6.
1998: V A Selivanov; François Ichas; Ekhson L Holmuhamedov; LS Jouaville; Y V Evtodienko; Jean-Pierre Mazat
A model of mitochondrial Ca(2+)-induced Ca2+ release simulating the Ca2+ oscillations and spikes generated by mitochondria.
Biophysical chemistry 1998;72(1-2):111-21.
1997: François Ichas; LS Jouaville; Jean-Pierre Mazat
Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals.
Cell 1997;89(7):1145-53.
1996: Yu V Evtodienko; Vera V Teplova; S S Sidash; François Ichas; Jean-Pierre Mazat
Microtubule-active drugs suppress the closure of the permeability transition pore in tumour mitochondria.
FEBS letters 1996;393(1):86-8.
1995: François Sztark; François Ichas; Jean-Pierre Mazat; Philippe Dabadie
Propofol and cellular calcium homeostasis.
Anesthesiology 1995;83(6):1386.
1995: LS Jouaville; François Ichas; Ekhson L Holmuhamedov; Patricia Camacho; James D Lechleiter
Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes.
Nature 1995;377(6548):438-41.
1995: François Sztark; François Ichas; R Ouhabi; Philippe Dabadie; Jean-Pierre Mazat
Effects of the anaesthetic propofol on the calcium-induced permeability transition of rat heart mitochondria: direct pore inhibition and shift of the gating potential.
FEBS letters 1995;368(1):101-4.
1994: François Ichas; LS Jouaville; S S Sidash; Jean-Pierre Mazat; Ekhson L Holmuhamedov
Mitochondrial calcium spiking: a transduction mechanism based on calcium-induced permeability transition involved in cell calcium signalling.
FEBS letters 1994;348(2):211-5.