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Takafumi Ichida

Research Profile

Disorders

Anatomy

Procedures

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Hepacivirus

Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Kenichi Takayasu; Shigeki Arii; Takafumi Ichida; Namiki Izumi; Norihiro Kokudo; Yonson Ku; Masatoshi Kudo; Masatoshi Makuuchi; Osamu Matsui; Yutaka Matsuyama; Osamu Nakashima; Michiie Sakamoto
Clinical implication of hypovascular hepatocellular carcinoma studied in 4,474 patients with solitary tumour equal or less than 3 cm.
Masaaki Takamura; Satoshi Yamagiwa; Takafumi Ichida; Yasunobu Matsuda; Yutaka Aoyagi
Involvement of liver-intestine cadherin in cancer progression.
Kenichi Takayasu; Shigeki Arii; Takafumi Ichida; Namiki Izumi; Norihiro Kokudo; Yonson Ku; Masatoshi Kudo; Osamu Matsui; Yutaka Matsuyama; Osamu Nakashima; Michiie Sakamoto; Makuuchi Masatoshi
Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines.

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All Publications

2013: Kenichi Takayasu; Shigeki Arii; Takafumi Ichida; Namiki Izumi; Norihiro Kokudo; Yonson Ku; Masatoshi Kudo; Masatoshi Makuuchi; Osamu Matsui; Yutaka Matsuyama; Osamu Nakashima; Michiie Sakamoto
Clinical implication of hypovascular hepatocellular carcinoma studied in 4,474 patients with solitary tumour equal or less than 3 cm.
Liver international : official journal of the International Association for the Study of the Liver 2013;33(5):762-70.
2013: Masaaki Takamura; Satoshi Yamagiwa; Takafumi Ichida; Yasunobu Matsuda; Yutaka Aoyagi
Involvement of liver-intestine cadherin in cancer progression.
Medical molecular morphology 2013;46(1):1-7.
2012: Kenichi Takayasu; Shigeki Arii; Takafumi Ichida; Namiki Izumi; Norihiro Kokudo; Yonson Ku; Masatoshi Kudo; Osamu Matsui; Yutaka Matsuyama; Osamu Nakashima; Michiie Sakamoto; Makuuchi Masatoshi
Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines.
Journal of hepatology 2012;56(4):886-92.
2011: Yasunobu Matsuda; Takafumi Ichida; Manabu Fukumoto
Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies.
Medical molecular morphology 2011;44(3):117-24.
2010: Masaaki Takamura; Satoshi Yamagiwa; Toshifumi Wakai; Yasushi Tamura; Hiroteru Kamimura; Takashi Kato; Atsunori Tsuchiya; Yasunobu Matsuda; Yoshio Shirai; Takafumi Ichida; Yoichi Ajioka; Yutaka Aoyagi
Loss of liver-intestine cadherin in human intrahepatic cholangiocarcinoma promotes angiogenesis by up-regulating metal-responsive transcription factor-1 and placental growth factor.
International journal of oncology 2010;36(1):245-54.
2009: Atsunori Tsuchiya; Hiroteru Kamimura; Masaaki Takamura; Satoshi Yamagiwa; Yasunobu Matsuda; Yoshinobu Sato; Minoru Nomoto; Takafumi Ichida; Yutaka Aoyagi
Clinicopathological analysis of CD133 and NCAM human hepatic stem/progenitor cells in damaged livers and hepatocellular carcinomas.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(11):1080-90.
2009: Yasunobu Matsuda; Takafumi Ichida
Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis.
Medical molecular morphology 2009;42(3):138-42.
2009: Satoshi Yamagiwa; Hiroteru Kamimura; Takafumi Ichida
Natural killer cell receptors and their ligands in liver diseases.
Medical molecular morphology 2009;42(1):1-8.
2008: Shogo Ohkoshi; Akira Yoshimura; Satoshi Yamamoto; Masahiko Yano; So Kurita; Kazuhide Yamazaki; Yo-Hei Aoki; Satoshi Yamagiwa; Hiroto Wakabayashi; Motoya Sugiyama; Tohru Takahashi; Tohru Ishikawa; Yasunobu Matsuda; Takafumi Ichida; Tomoteru Kamimura; Yutaka Aoyagi
Successful treatment with lamivudine may correlate with reduction of serum ferritin levels in the patients with chronic hepatitis and liver cirrhosis type B.
Hepatology international 2008;2(3):382-7.
2008: Satoshi Yamagiwa; Yasunobu Matsuda; Takafumi Ichida; Yutaka Honda; Masaaki Takamura; Satoshi Sugahara; Toru Ishikawa; Shogo Ohkoshi; Yoshinobu Sato; Yutaka Aoyagi
Sustained response to interferon-alpha plus ribavirin therapy for chronic hepatitis C is closely associated with increased dynamism of intrahepatic natural killer and natural killer T cells.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(7):664-72.
2007: Satoshi Yamagiwa; Takafumi Ichida
Recurrence of primary biliary cirrhosis and primary sclerosing cholangitis after liver transplantation in Japan.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37 Suppl 3():S449-54.
2007: Yutaka Honda; Satoshi Yamagiwa; Yasunobu Matsuda; Masaaki Takamura; Takafumi Ichida; Yutaka Aoyagi
Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis.
Journal of hepatology 2007;47(3):404-11.
2007: Mariko Hokari; Yasunobu Matsuda; Toshifumi Wakai; Yoshio Shirai; Munehiro Sato; Atsunori Tsuchiya; Masaaki Takamura; Satoshi Yamagiwa; Kenji Suzuki; Shogo Ohkoshi; Takafumi Ichida; Hiroshi Kawachi; Yutaka Aoyagi
Tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 potentates the anchorage-independent growth of human hepatoma HepG2 cells.
Life sciences 2007;81(4):336-45.
2006: Yasunobu Matsuda; Takafumi Ichida
p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis.
Medical molecular morphology 2006;39(4):169-75.
2006: Xiu Hua Yang; Satoshi Yamagiwa; Takafumi Ichida; Yasunobu Matsuda; Satoshi Sugahara; Hisami Watanabe; Yoshinobu Sato; Toru Abo; David A Horwitz; Yutaka Aoyagi
Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma.
Journal of hepatology 2006;45(2):254-62.
2006: Nobuyuki Honma; Takuya Genda; Yasunobu Matsuda; Satoshi Yamagiwa; Masaaki Takamura; Takafumi Ichida; Yutaka Aoyagi
MEK/ERK signaling is a critical mediator for integrin-induced cell scattering in highly metastatic hepatocellular carcinoma cells.
Laboratory investigation; a journal of technical methods and pathology 2006;86(7):687-96.
2005: Yasunobu Matsuda; Satoshi Yamagiwa; Masaaki Takamura; Yutaka Honda; Yuiko Ishimoto; Takafumi Ichida; Yutaka Aoyagi
Overexpressed Id-1 is associated with a high risk of hepatocellular carcinoma development in patients with cirrhosis without transcriptional repression of p16.
Cancer 2005;104(5):1037-44.
2005: Ryoko Miyakawa; Takafumi Ichida; Satoshi Yamagiwa; Chikako Miyaji; Hisami Watanabe; Yoshinobu Sato; Hisashi Yokoyama; Chika Tsukada; Yuiko Ishimoto; Satoshi Sugahara; Xiu Hua Yang; Toru Abo; Hitoshi Asakura
Hepatic natural killer and natural killer T cells markedly decreased in two cases of drug-induced fulminant hepatic failure rescued by living donor liver transplantation.
Journal of gastroenterology and hepatology 2005;20(7):1126-30.
2005: Koji Watanabe; Toru Takahashi; Sumio Takahashi; Shogo Okoshi; Takafumi Ichida; Yutaka Aoyagi
Comparative study of genotype B and C hepatitis B virus-induced chronic hepatitis in relation to the basic core promoter and precore mutations.
Journal of gastroenterology and hepatology 2005;20(3):441-9.
2004: Toru Ishikawa; Takafumi Ichida; Junji Yokoyama; Yasunobu Matsuda; Toshiaki Watanabe; Hitoshi Asakura
Complete disappearance of pulmonary metastases in a case of hepatocellular carcinoma treated with docetaxel-based systemic chemotherapy.
Journal of gastroenterology and hepatology 2004;19(12):1423-6.
2004: Yasunori Tsuboi; Takafumi Ichida; Soichi Sugitani; Takuya Genda; Jun Inayoshi; Masaaki Takamura; Yasunobu Matsuda; Minoru Nomoto; Yutaka Aoyagi
Overexpression of extracellular signal-regulated protein kinase and its correlation with proliferation in human hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(5):432-6.
2004: Masaaki Takamura; Takafumi Ichida; Yasunobu Matsuda; Masaaki Kobayashi; Satoshi Yamagiwa; Takuya Genda; Kazuhiko Shioji; Satoru Hashimoto; Minoru Nomoto; Katsuyoshi Hatakeyama; Yoichi Ajioka; Michiie Sakamoto; Setsuo Hirohashi; Yutaka Aoyagi
Reduced expression of liver-intestine cadherin is associated with progression and lymph node metastasis of human colorectal carcinoma.
Cancer letters 2004;212(2):253-9.
2004: Masaaki Takamura; Takafumi Ichida; Junji Yokoyama; Yasunobu Matsuda; Minoru Nomoto; Yutaka Aoyagi
Recurrence of hepatocellular carcinoma 102 months after successful eradication and removal of membranous obstruction of the inferior vena cava.
Journal of gastroenterology 2004;39(7):681-4.
2003: Yasunobu Matsuda; Takafumi Ichida; Takuya Genda; Satoshi Yamagiwa; Yutaka Aoyagi; Hitoshi Asakura
Loss of p16 contributes to p27 sequestration by cyclin D(1)-cyclin-dependent kinase 4 complexes and poor prognosis in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3389-96.
2003: Kenta Suzuki; Shogo Ohkoshi; Masahiko Yano; Takafumi Ichida; Mitsuhiro Takimoto; Akira Naitoh; Shigeki Mori; Kojiro Hata; Kentaro Igarashi; Hidenori Hara; Hironobu Ohta; Kenji Soga; Toshiaki Watanabe; Tomoteru Kamimura; Yutaka Aoyagi
Sustained biochemical remission after interferon treatment may closely be related to the end of treatment biochemical response and associated with a lower incidence of hepatocarcinogenesis.
Liver international : official journal of the International Association for the Study of the Liver 2003;23(3):143-7.
2003: Jun Inayoshi; Takafumi Ichida; Soichi Sugitani; Yasunori Tsuboi; Takuya Genda; Nobuyuki Honma; Hitoshi Asakura
Gross appearance of hepatocellular carcinoma reflects E-cadherin expression and risk of early recurrence after surgical treatment.
Journal of gastroenterology and hepatology 2003;18(6):673-7.
2003: Yoshinobu Sato; Takafumi Ichida; Hisami Watanabe; Satoshi Yamamoto; Hiroshi Oya; Hideki Nakatsuka; Takashi Kobayashi; Takaoki Watanabe; Hiroshi Kameyama; Katsuyoshi Hatakeyama
Repeating intraportal donor-specific transfusion may induce tolerance following adult living-related donor liver transplantation.
Hepato-gastroenterology 2003;50(51):601-6.
2003: Masaaki Takamura; Michiie Sakamoto; Yoshinori Ino; Takeshi Shimamura; Takafumi Ichida; Hitoshi Asakura; Setsuo Hirohashi
Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas.
Cancer science 2003;94(5):425-30.
2002: Shogo Okoshi; Masato Igarashi; Takeshi Suda; Hiroshi Iwamatsu; Kohji Watanabe; Kiyoshi Ishihara; Norio Ogata; Minoru Nomoto; Toru Takahashi; Takafumi Ichida; Hitoshi Asakura; Koei Nihei; Isao Kurosaki
Remote development of hepatocellular carcinoma in patients with liver cirrhosis type B serologically cured for HBs antigenemia with long-standing normalization of ALT values.
Digestive diseases and sciences 2002;47(9):2002-6.
2002: Yuichi Sato; Mitsuya Iwafuchi; Jun-Ichi Ueki; Akira Yoshimura; Tsutomu Mochizuki; Hirotaka Motoyama; Kazuhito Sugimura; Terasu Honma; Rintaro Narisawa; Takafumi Ichida; Hitoshi Asakura; D H Van Thiel
Gastric carcinoid tumors without autoimmune gastritis in Japan: a relationship with Helicobacter pylori infection.
Digestive diseases and sciences 2002;47(3):579-85.
2002: Kazuhiro Uehara; Takafumi Ichida; Satoshi Sugahara; Toru Ishikawa; Satoshi Yamagiwa; Yuhei Yoshida; Minoru Nomoto; Masashi Katoh; Hiroshi Satoh; Hisami Watanabe; Toru Abo; Hitoshi Asakura
Systemic administration of liposome-encapsulated OK-432 prolongs the survival of rats with hepatocellular carcinoma through the induction of IFN-gamma-producing hepatic lymphocytes.
Journal of gastroenterology and hepatology 2002;17(1):81-90.
2002: Mitsuhiro Takimoto; Shogo Ohkoshi; Takafumi Ichida; Yasuo Takeda; Minoru Nomoto; Hitoshi Asakura; Akira Naito; Shigeki Mori; Kojiro Hata; Kentaro Igarashi; Hidenori Hara; Hironobu Ohta; Kenji Soga; Toshiaki Watanabe; Tomoteru Kamimura
Interferon inhibits progression of liver fibrosis and reduces the risk of hepatocarcinogenesis in patients with chronic hepatitis C: a retrospective multicenter analysis of 652 patients.
Digestive diseases and sciences 2002;47(1):170-6.
2001: Toru Ishikawa; Takafumi Ichida; Satoshi Yamagiwa; Satoshi Sugahara; Kazuhiro Uehara; S Okoshi; Hitoshi Asakura
High viral loads, serum alanine aminotransferase and gender are predictive factors for the development of hepatocellular carcinoma from viral compensated liver cirrhosis.
Journal of gastroenterology and hepatology 2001;16(11):1274-81.
2001: T Ishikawa; Takafumi Ichida
[Features of hepatitis B virus-related hepatocellular carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 6():435-9.
2001: Takafumi Ichida; Shogo Ohkoshi; Mitsuhiro Takimoto; T Ishikawa
[Interferon therapy to chronic hepatitis type C for the prevention of hepatocarcinogenesis].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(7):1331-7.
2001: Toru Ishikawa; Takafumi Ichida; Soichi Sugitani; Yasunori Tsuboi; Takuya Genda; Satoshi Sugahara; Kazuhiro Uehara; Jun Inayoshi; J Yokoyama; Yuiko Ishimoto; Hitoshi Asakura
Improved survival with oral administration of enteric-coated tegafur/uracil for advanced stage IV-A hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2001;16(4):452-9.
2001: Masaaki Takamura; Michiie Sakamoto; Takuya Genda; Takafumi Ichida; Hitoshi Asakura; Setsuo Hirohashi
Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.
Hepatology (Baltimore, Md.) 2001;33(3):577-81.
2000: M Uchida; Takafumi Ichida; K Sato; K Yonekura; Satoshi Yamagiwa; Satoshi Sugahara; Hitoshi Asakura
Detection of intracellular interleukin-2 production in peripheral T lymphocytes by flow cytometry in patients with pancreatobiliary malignancies.
Journal of gastroenterology and hepatology 2000;15(10):1212-8.
2000: S Matsui; Takafumi Ichida; M Watanabe; Soichi Sugitani; T Suda; T Takahashi; Hitoshi Asakura
Clinical features and etiology of hepatocellular carcinoma arising in patients with membranous obstruction of the inferior vena cava: in reference to hepatitis viral infection.
Journal of gastroenterology and hepatology 2000;15(10):1205-11.
2000: K Yonekura; Takafumi Ichida; K Sato; Satoshi Yamagiwa; M Uchida; Satoshi Sugahara; S Ito; Toru Abo; Hitoshi Asakura
Liver-infiltrating CD56 positive T lymphocytes in hepatitis C virus infection.
Liver 2000;20(5):357-65.
2000: Toru Ishikawa; Takafumi Ichida; Yasunobu Matsuda; Soichi Sugitani; M Sugiyama; T Kato; H Miyazaki; Hitoshi Asakura
Expression of hepatic thrombopoietin mRNA in primary cultured hepatocytes and in rats with acute liver injury or bone marrow suppression with or without cirrhosis.
Journal of gastroenterology and hepatology 2000;15(6):647-53.
2000: Satoshi Yamagiwa; Takafumi Ichida; K Sato; Satoshi Sugahara; K Yonekura; M Uchida; Kazuhiro Uehara; M Katoh; H Satoh; Toru Abo; Hitoshi Asakura
Liposome-encapsulated OK-432 specifically and sustainedly induces hepatic natural killer cells and intermediate T cell receptor cells.
Journal of gastroenterology and hepatology 2000;15(5):542-9.
2000: T Satoh; Takafumi Ichida; Yasunobu Matsuda; M Sugiyama; K Yonekura; Toru Ishikawa; Hitoshi Asakura
Interaction between hyaluronan and CD44 in the development of dimethylnitrosamine-induced liver cirrhosis.
Journal of gastroenterology and hepatology 2000;15(4):402-11.
2000: Takuya Genda; Michiie Sakamoto; Takafumi Ichida; Hitoshi Asakura; Setsuo Hirohashi
Loss of cell-cell contact is induced by integrin-mediated cell-substratum adhesion in highly-motile and highly-metastatic hepatocellular carcinoma cells.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):387-94.
1999: Y Sato; K Sugimura; T Mochizuki; Terasu Honma; H Suriki; K Tashiro; K Ishizuka; Rintaro Narisawa; Takafumi Ichida; D H Van Thiel; Hitoshi Asakura
Regional differences on production of chemokines in gastric mucosa between Helicobacter pylori-positive duodenal ulcer and gastric ulcer.
Digestive diseases and sciences 1999;44(12):2390-6.
1999: Takuya Genda; Michiie Sakamoto; Takafumi Ichida; Hitoshi Asakura; M Kojiro; S Narumiya; Setsuo Hirohashi
Cell motility mediated by rho and Rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1999;30(4):1027-36.
1999: T Ishikawa; Takafumi Ichida; Y Ishimoto; J Yokoyama; M Nomoto; Yusuke Ebe; H Usuda; Makoto Naito; H Asakura
Complete remission of multiple hepatocellular carcinomas associated with hepatitis C virus-related, decompensated liver cirrhosis by oral administration of enteric-coated tegafur/uracil.
The American journal of gastroenterology 1999;94(6):1682-5.
1999: Yasunobu Matsuda; Takafumi Ichida; J Matsuzawa; K Sugimura; Hitoshi Asakura
p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma.
Gastroenterology 1999;116(2):394-400.
1998: Y Tanaka; Takafumi Ichida; M Nomoto; Y Matsuda; Hitoshi Asakura
Areas of sinusoidal surface hepatocyte nuclear predominance in type C chronic hepatitis.
Liver 1998;18(6):383-90.
1998: N Waguri; Takafumi Ichida; R Fujimaki; Toru Ishikawa; M Nomoto; Hitoshi Asakura; T Nakamaru; A Saitoh; M Arakawa; K Saitoh; K Takahashi
Fibrosing cholestatic hepatitis after living related-donor renal transplantation.
Journal of gastroenterology and hepatology 1998;13(11):1133-7.
1998: Toru Ishikawa; Takafumi Ichida; Yasunobu Matsuda; Soichi Sugitani; M Sugiyama; T Kato; H Miyazaki; Hitoshi Asakura
Reduced expression of thrombopoietin is involved in thrombocytopenia in human and rat liver cirrhosis.
Journal of gastroenterology and hepatology 1998;13(9):907-13.
1998: Soichi Sugitani; Michiie Sakamoto; Takafumi Ichida; Takuya Genda; Hitoshi Asakura; Setsuo Hirohashi
Hyperplastic foci reflect the risk of multicentric development of human hepatocellular carcinoma.
Journal of hepatology 1998;28(6):1045-53.
1998: S Itoh; Takafumi Ichida; T Yoshida; A Hayakawa; M Uchida; T Tashiro-Itoh; Y Matsuda; K Ishihara; Hitoshi Asakura
Autoantibodies against a 210 kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis.
Journal of gastroenterology and hepatology 1998;13(3):257-65.
1998: M Sugiyama; Takafumi Ichida; T Sato; Toru Ishikawa; Yasunobu Matsuda; Hitoshi Asakura
Expression of activin A is increased in cirrhotic and fibrotic rat livers.
Gastroenterology 1998;114(3):550-8.
1997: T Tashiro-Itoh; Takafumi Ichida; Y Matsuda; T Satoh; M Sugiyama; Y Tanaka; T Ishikawa; S Itoh; M Nomoto; Hitoshi Asakura
Metallothionein expression and concentrations of copper and zinc are associated with tumor differentiation in hepatocellular carcinoma.
Liver 1997;17(6):300-6.
1997: Y Miyazaki; T Mitsuma; Takafumi Ichida; H Odazima; K Ishihara; Hitoshi Asakura
Amplification of BCR protein associated with oncogenesis in human hepatocellular carcinoma.
Digestive diseases and sciences 1997;42(5):927-37.
1997: K Kuwana; Takafumi Ichida; T Kamimura; S Ohkoshi; N Ogata; T Harada; K Endoh; Hitoshi Asakura
Risk factors and the effect of interferon therapy in the development of hepatocellular carcinoma: a multivariate analysis in 343 patients.
Journal of gastroenterology and hepatology 1997;12(2):149-55.
1996: Takafumi Ichida; Soichi Sugitani; T Satoh; Y Matsuda; M Sugiyama; K Yonekura; Toru Ishikawa; H Asakura
Localization of hyaluronan in human liver sinusoids: a histochemical study using hyaluronan-binding protein.
Liver 1996;16(6):365-71.