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Haruyo Ichikawa

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Publications

TOP 3
Ajaikumar Kunnumakkara; Haruyo Ichikawa; Preetha Anand; Chiramel J Mohankumar; Padmanabhan S Hema; Mangalam S Nair; Bharat B Aggarwal
Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
Santosh K Sandur; Haruyo Ichikawa; Manoj Pandey; Ajaikumar Kunnumakkara; Bokyung Sung; Gautam Sethi; Bharat B Aggarwal
Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane).
D G Jackson-Bernitsas; Haruyo Ichikawa; Yasunari Takada; Jeffrey N Myers; X L Lin; Bryant G Darnay; Madan M Chaturvedi; Bharat B Aggarwal
Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

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2008: Ajaikumar Kunnumakkara; Haruyo Ichikawa; Preetha Anand; Chiramel J Mohankumar; Padmanabhan S Hema; Mangalam S Nair; Bharat B Aggarwal
Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
Molecular cancer therapeutics 2008;7(10):3306-17.
2007: Santosh K Sandur; Haruyo Ichikawa; Manoj Pandey; Ajaikumar Kunnumakkara; Bokyung Sung; Gautam Sethi; Bharat B Aggarwal
Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane).
Free radical biology & medicine 2007;43(4):568-80.
2007: D G Jackson-Bernitsas; Haruyo Ichikawa; Yasunari Takada; Jeffrey N Myers; X L Lin; Bryant G Darnay; Madan M Chaturvedi; Bharat B Aggarwal
Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.
Oncogene 2007;26(10):1385-97.
2007: Yasunari Takada; Haruyo Ichikawa; Abujiang Pataer; Stephen G Swisher; Bharat B Aggarwal
Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
Oncogene 2007;26(8):1201-12.
2007: Bharat B Aggarwal; Chitra Sundaram; Nikita Malani; Haruyo Ichikawa
Curcumin: the Indian solid gold.
Advances in experimental medicine and biology 2007;595():1-75.
2007: Santosh K Sandur; Kwang Seok Ahn; Haruyo Ichikawa; Gautam Sethi; Shishir Shishodia; Robert A Newman; Bharat B Aggarwal
Zyflamend, a polyherbal preparation, inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of NF-kappa B activation and NF-kappa B-regulated gene products.
Nutrition and cancer 2007;57(1):78-87.
2007: Prachi Garodia; Haruyo Ichikawa; Nikita Malani; Gautam Sethi; Bharat B Aggarwal
From ancient medicine to modern medicine: ayurvedic concepts of health and their role in inflammation and cancer.
Journal of the Society for Integrative Oncology 2007;5(1):25-37.
2006: Bharat B Aggarwal; Gautam Sethi; Kwang Seok Ahn; Santosh K Sandur; Manoj Pandey; Ajaikumar Kunnumakkara; Bokyung Sung; Haruyo Ichikawa
Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution.
Annals of the New York Academy of Sciences 2006;1091():151-69.
2006: Haruyo Ichikawa; Mangalam S Nair; Yasunari Takada; D B Alan Sheeja; M A Suresh Kumar; Oommen V Vilaverthottathil Oommen; Bharat B Aggarwal
Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5910-8.
2006: Santosh K Sandur; Haruyo Ichikawa; Gautam Sethi; Kwang Seok Ahn; Bharat B Aggarwal
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
The Journal of biological chemistry 2006;281(25):17023-33.
2006: Haruyo Ichikawa; Yasunari Takada; Shishir Shishodia; Bolleddula Jayaprakasam; Muraleedharan G Nair; Bharat B Aggarwal
Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression.
Molecular cancer therapeutics 2006;5(6):1434-45.
2006: Haruyo Ichikawa; Akira Murakami; Bharat B Aggarwal
1'-Acetoxychavicol acetate inhibits RANKL-induced osteoclastic differentiation of RAW 264.7 monocytic cells by suppressing nuclear factor-kappaB activation.
Molecular cancer research : MCR 2006;4(4):275-81.
2006: Yasunari Takada; Ann M Gillenwater; Haruyo Ichikawa; Bharat B Aggarwal
Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.
The Journal of biological chemistry 2006;281(9):5612-22.
2006: Yasunari Takada; Haruyo Ichikawa; Vladimir Badmaev; Bharat B Aggarwal
Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):3127-40.
2006: Bharat B Aggarwal; Haruyo Ichikawa; Prachi Garodia; Priya Weerasinghe; Gautam Sethi; Indra D Bhatt; Manoj Pandey; Shishir Shishodia; Muraleedharan G Nair
From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer.
Expert opinion on therapeutic targets 2006;10(1):87-118.
2006: Haruyo Ichikawa; Bharat B Aggarwal
Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):662-8.
2006: Sita Aggarwal; Haruyo Ichikawa; Yasunari Takada; Santosh K Sandur; Shishir Shishodia; Bharat B Aggarwal
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
Molecular pharmacology 2006;69(1):195-206.
2005: Bharat B Aggarwal; Haruyo Ichikawa
Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Cell cycle (Georgetown, Tex.) 2005;4(9):1201-15.
2005: Haruyo Ichikawa; Yasunari Takada; Akira Murakami; Bharat B Aggarwal
Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7383-92.
2004: Bharat B Aggarwal; Yasunari Takada; Shishir Shishodia; Angelica M Gutierrez; Oommen V Vilaverthottathil Oommen; Haruyo Ichikawa; Yuh Baba; Ashok Kumar
Nuclear transcription factor NF-kappa B: role in biology and medicine.
Indian journal of experimental biology 2004;42(4):341-53.