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Tohru Ichimura

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Yoshinari Asaoka; Fumihiko Kanai; Tohru Ichimura; Keisuke Tateishi; Yasuo Tanaka; Miki Ohta; Motoko Seto; Motohisa Tada; Hideaki Ijichi; Tsuneo Ikenoue; Takao Kawabe; Toshiaki Isobe; Michael B Yaffe; Masao Omata
Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.
Tohru Ichimura; Masato Taoka; Yasukazu Hozumi; Kaoru Goto; Hiroshi Tokumitsu
14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.
Yasuo Tanaka; Jun Imamura; Fumihiko Kanai; Tohru Ichimura; Toshiaki Isobe; Manabu Koike; Yotaro Kudo; Keisuke Tateishi; Tsuneo Ikenoue; Hideaki Ijichi; Yutaka Yamaji; Haruhiko Yoshida; Takao Kawabe; Masao Omata
Runx3 interacts with DNA repair protein Ku70.

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All Publications

2010: Yoshinari Asaoka; Fumihiko Kanai; Tohru Ichimura; Keisuke Tateishi; Yasuo Tanaka; Miki Ohta; Motoko Seto; Motohisa Tada; Hideaki Ijichi; Tsuneo Ikenoue; Takao Kawabe; Toshiaki Isobe; Michael B Yaffe; Masao Omata
Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.
The Journal of biological chemistry 2010;285(6):4185-94.
2008: Tohru Ichimura; Masato Taoka; Yasukazu Hozumi; Kaoru Goto; Hiroshi Tokumitsu
14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.
FEBS letters 2008;582(5):661-5.
2007: Yasuo Tanaka; Jun Imamura; Fumihiko Kanai; Tohru Ichimura; Toshiaki Isobe; Manabu Koike; Yotaro Kudo; Keisuke Tateishi; Tsuneo Ikenoue; Hideaki Ijichi; Yutaka Yamaji; Haruhiko Yoshida; Takao Kawabe; Masao Omata
Runx3 interacts with DNA repair protein Ku70.
Experimental cell research 2007;313(15):3251-60.
2007: Kazue Kakiuchi; Yoshio Yamauchi; Masato Taoka; Maki Iwago; Tomoko Fujita; Takashi Ito; Si-Young Song; Akira Sakai; Toshiaki Isobe; Tohru Ichimura
Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae.
Biochemistry 2007;46(26):7781-92.
2006: Kazunori Nagaki; Hisao Yamamura; Shoichi Shimada; Taro Saito; Shin-ichi Hisanaga; Masato Taoka; Toshiaki Isobe; Tohru Ichimura
14-3-3 Mediates phosphorylation-dependent inhibition of the interaction between the ubiquitin E3 ligase Nedd4-2 and epithelial Na+ channels.
Biochemistry 2006;45(21):6733-40.
2006: Yuetsu Tanaka; Fumihiko Kanai; Tohru Ichimura; Keisuke Tateishi; Yoshinari Asaoka; Bayasi Guleng; Amarsanaa Jazag; Miki Ohta; Jun Imamura; Tsuneo Ikenoue; Hideaki Ijichi; Takao Kawabe; Toshiaki Isobe; Masao Omata
The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab1.
Oncogene 2006;25(4):633-42.
2005: Takashi Shinkawa; Masato Taoka; Yoshio Yamauchi; Tohru Ichimura; Hiroyuki Kaji; Nobuhiro Takahashi; Toshiaki Isobe
STEM: a software tool for large-scale proteomic data analyses.
Journal of proteome research 2005;4(5):1826-31.
2005: Motoyuki Otsuka; Naoya Kato; Tohru Ichimura; Shinya Abe; Yasuo Tanaka; Hiroyoshi Taniguchi; Yujin Hoshida; Masaru Moriyama; Yue Wang; Run-Xuan Shao; Dharel Narayan; Ryosuke Muroyama; Fumihiko Kanai; Takao Kawabe; Toshiaki Isobe; Masao Omata
Vitamin K2 binds 17beta-hydroxysteroid dehydrogenase 4 and modulates estrogen metabolism.
Life sciences 2005;76(21):2473-82.
2005: Tohru Ichimura; Hisao Yamamura; Kaname Sasamoto; Yuri Tominaga; Masato Taoka; Kazue Kakiuchi; Takashi Shinkawa; Nobuhiro Takahashi; Shoichi Shimada; Toshiaki Isobe
14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.
The Journal of biological chemistry 2005;280(13):13187-94.
2004: Tohru Ichimura; Hiroyuki Kubota; Takeshi Goma; Noboru Mizushima; Yoshinori Ohsumi; Maki Iwago; Kazue Kakiuchi; Hossain Uddin Shekhar; Takashi Shinkawa; Masato Taoka; Takashi Ito; Toshiaki Isobe
Transcriptomic and proteomic analysis of a 14-3-3 gene-deficient yeast.
Biochemistry 2004;43(20):6149-58.
2003: Masato Taoka; Tohru Ichimura; Akiko Wakamiya-Tsuruta; Yoshiaki Kubota; Takeshi Araki; Takashi Obinata; Toshiaki Isobe
V-1, a protein expressed transiently during murine cerebellar development, regulates actin polymerization via interaction with capping protein.
The Journal of biological chemistry 2003;278(8):5864-70.
2002: Tohru Ichimura; Akiko Wakamiya-Tsuruta; Chiharu Itagaki; Masato Taoka; Toshiya Hayano; Tohru Natsume; Toshiaki Isobe
Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein.
Biochemistry 2002;41(17):5566-72.
1999: M Shimada; M Saito; T Katakai; A Shimizu; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Molecular cloning and splicing isoforms of mouse p144, a homologue of CA150.
Journal of biochemistry 1999;126(6):1033-42.
1999: Chiharu Itagaki; Toshiaki Isobe; Masato Taoka; Tohru Natsume; N Nomura; Tsuneyoshi Horigome; Saburo Omata; H Ichinose; Toshiharu Nagatsu; L A Greene; Tohru Ichimura
Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins.
Biochemistry 1999;38(47):15673-80.
1999: Chiharu Itagaki; Saburo Omata; Tohru Ichimura
[Regulation of intracellular signaling by 14-3-3 protein family: what's known now].
Seikagaku. The Journal of Japanese Biochemical Society 1999;71(10):1232-39.
1999: S Sasagawa; A Yamamoto; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
In vitro nuclear assembly with affinity-purified nuclear envelope precursor vesicle fractions, PV1 and PV2.
European journal of cell biology 1999;78(8):593-600.
1999: T Gohshi; M Shimada; S Kawahire; N Imai; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Molecular cloning of mouse p47, a second group mammalian RuvB DNA helicase-like protein: homology with those from human and Saccharomyces cerevisiae.
Journal of biochemistry 1999;125(5):939-46.
1999: N Kikuchi; T Gohshi; S Kawahire; T Tachibana; Y Yoneda; Toshiaki Isobe; Chun Ren Lim; Kenji Kohno; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Molecular shape and ATP binding activity of rat p50, a putative mammalian homologue of RuvB DNA helicase.
Journal of biochemistry 1999;125(3):487-94.
1997: N Imai; S Sasagawa; A Yamamoto; F Kikuchi; K Sekiya; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Characterization of the binding of nuclear envelope precursor vesicles and chromatin, and purification of the vesicles.
Journal of biochemistry 1997;122(5):1024-33.
1997: Y Ishida; Tohru Ichimura; H Sumi; Tsuneyoshi Horigome; Saburo Omata
Methylmercury alters the tyrosination status of tubulin in the brains of acutely intoxicated rats.
Toxicology 1997;122(3):171-81.
1997: Toshio Ogihara; Toshiaki Isobe; Tohru Ichimura; Masato Taoka; Masako Funaki; Hideyuki Sakoda; Yukiko Onishi; Kouichi Inukai; Motonobu Anai; Yasushi Fukushima; Masatoshi Kikuchi; Yoshio Yazaki; Yoshitaka Oka; Tomoichiro Asano
14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.
The Journal of biological chemistry 1997;272(40):25267-74.
1997: Tohru Ichimura; M Ito; Chiharu Itagaki; M Takahashi; Tsuneyoshi Horigome; Saburo Omata; S Ohno; Toshiaki Isobe
The 14-3-3 protein binds its target proteins with a common site located towards the C-terminus.
FEBS letters 1997;413(2):273-6.
1997: S Kawahire; M Takeuchi; T Gohshi; S Sasagawa; M Shimada; M Takahashi; T K Abe; T Ueda; Ryozo Kuwano; A Hikawa; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
cDNA cloning of nuclear localization signal binding protein NBP60, a rat homologue of lamin B receptor, and identification of binding sites of human lamin B receptor for nuclear localization signals and chromatin.
Journal of biochemistry 1997;121(5):881-9.
1996: S Makifuchi; M Takeuchi; S Kawahire; S Odani; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Characterization of p92, karyopherin beta, co-purified with N-acetylglucosamine-bearing nucleoporins from rat liver nuclear envelopes.
Journal of biochemistry 1996;120(4):716-24.
1996: S Kawahire; T Tachibana; M Umemoto; Y Yoneda; N Imai; M Saito; Tohru Ichimura; Saburo Omata; Tsuneyoshi Horigome
Subcellular distribution and phosphorylation of the nuclear localization signal binding protein, NBP60.
Experimental cell research 1996;222(2):385-94.
1995: Tohru Ichimura; J Uchiyama; O Kunihiro; M Ito; Tsuneyoshi Horigome; Saburo Omata; F Shinkai; H Kaji; Toshiaki Isobe
Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase.
The Journal of biological chemistry 1995;270(48):28515-8.
1993: Y Furukawa; N Ikuta; Saburo Omata; T Yamauchi; Toshiaki Isobe; Tohru Ichimura
Demonstration of the phosphorylation-dependent interaction of tryptophan hydroxylase with the 14-3-3 protein.
Biochemical and biophysical research communications 1993;194(1):144-9.
1991: S Tazawa; M Unuma; N Tondokoro; Y Asano; T Ohsumi; Tohru Ichimura; H Sugano
Identification of a membrane protein responsible for ribosome binding in rough microsomal membranes.
Journal of biochemistry 1991;109(1):89-98.