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Kazuei Igarashi

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Tomoko Yamashita; Kunio Fujiwara; Kyohei Higashi; Keiko Kashiwagi; Mizuho Nakamura; Kazuhiro Nishimura; Hiroyuki Okudaira; Ryotaro Saiki; Yusuke Terui; Mayuko Tome; Kazuei Igarashi
Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.
Kenta Watanabe; Kazuei Igarashi; Mitsukazu Kitada; Yuki Nakazato; Ryotaro Saiki; Itsuko Ishii
Acrolein-conjugated low-density lipoprotein induces macrophage foam cell formation.
Mizuho Nakamura; Ryotaro Saiki; Akihiko Sakamoto; Takehiro Suzuki; Yusuke Terui; Hideyuki Tomitori; Naoshi Dohmae; Kazuei Igarashi; Keiko Kashiwagi
Inactivation of GAPDH as one mechanism of acrolein toxicity.

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All Publications

2013: Tomoko Yamashita; Kunio Fujiwara; Kyohei Higashi; Keiko Kashiwagi; Mizuho Nakamura; Kazuhiro Nishimura; Hiroyuki Okudaira; Ryotaro Saiki; Yusuke Terui; Mayuko Tome; Kazuei Igarashi
Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.
The international journal of biochemistry & cell biology 2013;45(6):1042-50.
2013: Kenta Watanabe; Kazuei Igarashi; Mitsukazu Kitada; Yuki Nakazato; Ryotaro Saiki; Itsuko Ishii
Acrolein-conjugated low-density lipoprotein induces macrophage foam cell formation.
Atherosclerosis 2013;227(1):51-7.
2013: Mizuho Nakamura; Ryotaro Saiki; Akihiko Sakamoto; Takehiro Suzuki; Yusuke Terui; Hideyuki Tomitori; Naoshi Dohmae; Kazuei Igarashi; Keiko Kashiwagi
Inactivation of GAPDH as one mechanism of acrolein toxicity.
Biochemical and biophysical research communications 2013;430(4):1265-71.
2012: Hideyuki Tomitori; Keith Williams; Yuki Yoshizawa; Keiko Kashiwagi; Takashi Masuko; Satomi Mizuno; Kazuhiro Nishimura; Ryotaro Saiki; Akiko Suganami; Yutaka Tamura; Toshihiko Toida; Kazuei Igarashi
Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil.
The Journal of pharmacology and experimental therapeutics 2012;343(1):82-90.
2012: Madoka Yoshida; Kazumasa Fukuda; Kyohei Higashi; Itsuko Ishii; Keiko Kashiwagi; Takahiro Mikami; Mutsumi Mizoi; Takao Nakamura; Kazuhiro Nishimura; Ryotaro Saiki; Toshihiko Toida; Hideyuki Tomitori; Kazuei Igarashi
Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite.
Clinica chimica acta; international journal of clinical chemistry 2012;413(7-8):753-9.
2012: Itsuko Ishii; Hiromi Kaneko; Noritaka Ariyoshi; Kyohei Higashi; Kazuei Igarashi; Takaaki Suzuki; Yukari Suzuki; Masashi Uchida; Satoko Yagi; Mitsukazu Kitada
Correlation between antizyme 1 and differentiation of vascular smooth muscle cells cultured in honeycomb-like type-I collagen matrix.
Amino acids 2012;42(2-3):565-75.
2011: Kazuei Igarashi; Keiko Kashiwagi
Protein-conjugated acrolein as a biochemical marker of brain infarction.
Molecular nutrition & food research 2011;55(9):1332-41.
2011: Madoka Yoshida; Mutsumi Mizoi; Ryotaro Saiki; Eiichi Kobayashi; Naokatsu Saeki; Kenji Wakui; Tadafumi Kusaka; Hirotaka Takizawa; Koichi Kashiwado; Norikazu Suzuki; Kazumasa Fukuda; Takao Nakamura; Sakae Watanabe; Kei Tada; Hideyuki Tomitori; Keiko Kashiwagi; Kazuei Igarashi
Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age.
Clinica chimica acta; international journal of clinical chemistry 2011;412(3-4):339-42.
2011: Ryotaro Saiki; Hyerim Park; Itsuko Ishii; Madoka Yoshida; Kazuhiro Nishimura; Toshihiko Toida; Hideki Tatsukawa; Soichi Kojima; Yoshihiko Ikeguchi; Anthony E Pegg; Keiko Kashiwagi; Kazuei Igarashi
Brain infarction correlates more closely with acrolein than with reactive oxygen species.
Biochemical and biophysical research communications 2011;404(4):1044-9.
2011: Kazuei Igarashi; Keiko Kashiwagi
Use of polyamine metabolites as markers for stroke and renal failure.
Methods in molecular biology (Clifton, N.J.) 2011;720():395-408.
2011: Kazuei Igarashi; Keiko Kashiwagi
Characterization of genes for polyamine modulon.
Methods in molecular biology (Clifton, N.J.) 2011;720():51-65.
2010: Kyohei Higashi; Yoshiharu Sakamaki; Emiko Herai; Risa Demizu; Takeshi Uemura; Sunil D Saroj; Risa Zenda; Yusuke Terui; Kazuhiro Nishimura; Toshihiko Toida; Keiko Kashiwagi; Kazuei Igarashi
Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity.
The Journal of biological chemistry 2010;285(50):39061-9.
2010: Madoka Yoshida; Kyohei Higashi; Eiichi Kobayashi; Naokatsu Saeki; Kenji Wakui; Tadafumi Kusaka; Hirotaka Takizawa; Koichi Kashiwado; Norikazu Suzuki; Kazumasa Fukuda; Takao Nakamura; Sakae Watanabe; Kei Tada; Yoshiki Machi; Mutsumi Mizoi; Toshihiko Toida; T Kanzaki; Hideyuki Tomitori; Keiko Kashiwagi; Kazuei Igarashi
Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP.
Atherosclerosis 2010;211(2):475-9.
2010: Kazuei Igarashi; Keiko Kashiwagi
Characteristics of cellular polyamine transport in prokaryotes and eukaryotes.
Plant physiology and biochemistry : PPB / Société française de physiologie végétale 2010;48(7):506-12.
2010: Kyohei Higashi; Madoka Yoshida; Atsuko Igarashi; Kayoko Ito; Yoko Wada; Shuichi Murakami; Daisuke Kobayashi; Masaaki Nakano; Miwa Sohda; Takako Nakajima; Ichiei Narita; Toshihiko Toida; Keiko Kashiwagi; Kazuei Igarashi
Intense correlation between protein-conjugated acrolein and primary Sjögren's syndrome.
Clinica chimica acta; international journal of clinical chemistry 2010;411(5-6):359-63.
2010: Madoka Yoshida; Kyohei Higashi; Lihua Jin; Yoshiki Machi; Takehiro Suzuki; Akiko Masuda; Naoshi Dohmae; Akiko Suganami; Yutaka Tamura; Kazuhiro Nishimura; Toshihiko Toida; Hideyuki Tomitori; Keiko Kashiwagi; Kazuei Igarashi
Identification of acrolein-conjugated protein in plasma of patients with brain infarction.
Biochemical and biophysical research communications 2010;391(2):1234-9.
2010: Kazuei Igarashi; Keiko Kashiwagi
Modulation of cellular function by polyamines.
The international journal of biochemistry & cell biology 2010;42(1):39-51.
2009: Takeshi Uemura; Kyohei Higashi; Miki Takigawa; Toshihiko Toida; Keiko Kashiwagi; Kazuei Igarashi
Polyamine modulon in yeast-Stimulation of COX4 synthesis by spermidine at the level of translation.
The international journal of biochemistry & cell biology 2009;41(12):2538-45.
2009: Takashi Masuko; Rie Namiki; Yuta Nemoto; Muneharu Miyake; Yasuo Kizawa; Toyofumi Suzuki; Keiko Kashiwagi; Kazuei Igarashi; Tadashi Kusama
Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.
The Journal of pharmacology and experimental therapeutics 2009;331(2):522-30.
2009: Kazuhiro Nishimura; Hiroyuki Okudaira; Eriko Ochiai; Kyohei Higashi; Mayumi Kaneko; Itsuko Ishii; Tomoe Nishimura; Naoshi Dohmae; Keiko Kashiwagi; Kazuei Igarashi
Identification of proteins whose synthesis is preferentially enhanced by polyamines at the level of translation in mammalian cells.
The international journal of biochemistry & cell biology 2009;41(11):2251-61.
2009: Ryotaro Saiki; Kazuhiro Nishimura; Itsuko Ishii; Tomohiro Omura; Shigeru Okuyama; Keiko Kashiwagi; Kazuei Igarashi
Intense correlation between brain infarction and protein-conjugated acrolein.
Stroke; a journal of cerebral circulation 2009;40(10):3356-61.
2009: Madoka Yoshida; Hideyuki Tomitori; Yoshiki Machi; Daisuke Katagiri; Shiro Ueda; Kentaro Horiguchi; Eiichi Kobayashi; Naokatsu Saeki; Kazuhiro Nishimura; Itsuko Ishii; Keiko Kashiwagi; Kazuei Igarashi
Acrolein, IL-6 and CRP as markers of silent brain infarction.
Atherosclerosis 2009;203(2):557-62.
2009: Madoka Yoshida; Hideyuki Tomitori; Yoshiki Machi; Motofumi Hagihara; Kyohei Higashi; Hitomi Goda; Takeshi Ohya; Masaru Niitsu; Keiko Kashiwagi; Kazuei Igarashi
Acrolein toxicity: Comparison with reactive oxygen species.
Biochemical and biophysical research communications 2009;378(2):313-8.
2008: Kyohei Higashi; Yusuke Terui; Akiko Suganami; Yutaka Tamura; Kazuhiro Nishimura; Keiko Kashiwagi; Kazuei Igarashi
Selective structural change by spermidine in the bulged-out region of double-stranded RNA and its effect on RNA function.
The Journal of biological chemistry 2008;283(47):32989-94.
2008: Lihua Jin; Maki Miyazaki; Satomi Mizuno; Miki Takigawa; Tadao Hirose; Kazuhiro Nishimura; Toshihiko Toida; Keith Williams; Keiko Kashiwagi; Kazuei Igarashi
The pore region of N-methyl-D-aspartate receptors differentially influences stimulation and block by spermine.
The Journal of pharmacology and experimental therapeutics 2008;327(1):68-77.
2008: Takashi Masuko; Muneharu Miyake; Kuniko Kusama-Eguchi; Tohru Koike; Eiichi Kimura; Yasuo Kizawa; Keiko Kashiwagi; Kazuei Igarashi; Tadashi Kusama
Differential effects of linear and cyclic polyamines on NMDA receptor activities.
Neurochemistry international 2008;53(1-2):38-44.
2008: Kyohei Higashi; Yusuke Terui; Emire Inomata; Daisuke Katagiri; Yusuke Nomura; Tatsuhiko Someya; Kazuhiro Nishimura; Keiko Kashiwagi; Gota Kawai; Kazuei Igarashi
Selective structural change of bulged-out region of double-stranded RNA containing bulged nucleotides by spermidine.
Biochemical and biophysical research communications 2008;370(4):572-7.
2008: Kyohei Higashi; Hiroyuki Ishigure; Risa Demizu; Takeshi Uemura; Kunihiko Nishino; Akihito Yamaguchi; Keiko Kashiwagi; Kazuei Igarashi
Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.
Journal of bacteriology 2008;190(3):872-8.
2007: Kazuhiro Nishimura; Ai Sakuma; Tomoko Yamashita; Go Hirokawa; Hiroaki Imataka; Keiko Kashiwagi; Kazuei Igarashi
Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation.
Biochemical and biophysical research communications 2007;364(1):124-30.
2007: Takashi Masuko; Yuta Nemoto; Hiroki Nagaoka; Muneharu Miyake; Yasuo Kizawa; Kuniko Kusama-Eguchi; Keiko Kashiwagi; Kazuei Igarashi; Tadashi Kusama
Cleft-type cyclophanes confer neuroprotection against excitatory neurotoxicity in vitro and in vivo through inhibition of NMDA receptors.
Neuropharmacology 2007;53(4):515-23.
2007: Hiromitsu Takayama; Yuichi Yaegashi; Mariko Kitajima; Xia Han; Kazuhiro Nishimura; Shigeru Okuyama; Kazuei Igarashi
Design, synthesis, and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers.
Bioorganic & medicinal chemistry letters 2007;17(17):4729-32.
2007: Takeshi Uemura; Keiko Kashiwagi; Kazuei Igarashi
Polyamine uptake by DUR3 and SAM3 in Saccharomyces cerevisiae.
The Journal of biological chemistry 2007;282(10):7733-41.
2007: Yusuke Terui; Kyohei Higashi; Shiho Taniguchi; Ai Shigemasa; Kazuhiro Nishimura; Kaneyoshi Yamamoto; Keiko Kashiwagi; Akira Ishihama; Kazuei Igarashi
Enhancement of the synthesis of RpoN, Cra, and H-NS by polyamines at the level of translation in Escherichia coli cultured with glucose and glutamate.
Journal of bacteriology 2007;189(6):2359-68.
2007: Takashi Masuko; Hiroki Nagaoka; Muneharu Miyake; Koichi Metori; Yasuo Kizawa; Keiko Kashiwagi; Kazuei Igarashi; Tadashi Kusama
Cyclophane and acyclic cyclophane: novel channel blockers of N-methyl-D-aspartate receptor.
Neurochemistry international 2007;50(2):443-9.
2007: Lihua Jin; Hiromi Sugiyama; Miki Takigawa; Daisuke Katagiri; Hideyuki Tomitori; Kazuhiro Nishimura; Navneet Kaur; Otto Phanstiel; Mariko Kitajima; Hiromitsu Takayama; Tadashi Okawara; Keith Williams; Keiko Kashiwagi; Kazuei Igarashi
Comparative studies of anthraquinone- and anthracene-tetraamines as blockers of N-methyl-D-aspartate receptors.
The Journal of pharmacology and experimental therapeutics 2007;320(1):47-55.
2006: Kazuei Igarashi; S Ueda; K Yoshida; K Kashiwagi
Polyamines in renal failure.
Amino acids 2006;31(4):477-83.
2006: Waraporn Soksawatmaekhin; Takeshi Uemura; Natsuko Fukiwake; Keiko Kashiwagi; Kazuei Igarashi
Identification of the cadaverine recognition site on the cadaverine-lysine antiporter CadB.
The Journal of biological chemistry 2006;281(39):29213-20.
2006: Kazuei Igarashi
[Physiological functions of polyamines and regulation of polyamine content in cells].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2006;126(7):455-71.
2006: Kyohei Higashi; Keiko Kashiwagi; Shiho Taniguchi; Yusuke Terui; Kaneyoshi Yamamoto; Akira Ishihama; Kazuei Igarashi
Enhancement of +1 frameshift by polyamines during translation of polypeptide release factor 2 in Escherichia coli.
The Journal of biological chemistry 2006;281(14):9527-37.
2006: Kazuhiro Nishimura; Ritsuko Shiina; Keiko Kashiwagi; Kazuei Igarashi
Decrease in polyamines with aging and their ingestion from food and drink.
Journal of biochemistry 2006;139(1):81-90.
2006: Kazuei Igarashi; Keiko Kashiwagi
Polyamine Modulon in Escherichia coli: genes involved in the stimulation of cell growth by polyamines.
Journal of biochemistry 2006;139(1):11-6.
2005: Kenji Hoshino; Emi Momiyama; Kaori Yoshida; Kazuhiro Nishimura; Shinobu Sakai; Toshihiko Toida; Keiko Kashiwagi; Kazuei Igarashi
Polyamine transport by mammalian cells and mitochondria: role of antizyme and glycosaminoglycans.
The Journal of biological chemistry 2005;280(52):42801-8.
2005: Hideyuki Tomitori; Teruyoshi Usui; Naokatsu Saeki; Shiro Ueda; Hiroshi Kase; Kazuhiro Nishimura; Keiko Kashiwagi; Kazuei Igarashi
Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke.
Stroke; a journal of cerebral circulation 2005;36(12):2609-13.
2005: Reiko Homma; Akiko Mase; Toshihiko Toida; Keiko Kashiwagi; Kazuei Igarashi
Modulation of blood coagulation and fibrinolysis by polyamines in the presence of glycosaminoglycans.
The international journal of biochemistry & cell biology 2005;37(9):1911-20.
2005: Go Hirokawa; Romana M Nijman; V Samuel Raj; Hideko Kaji; Kazuei Igarashi; Akira Kaji
The role of ribosome recycling factor in dissociation of 70S ribosomes into subunits.
RNA (New York, N.Y.) 2005;11(8):1317-28.
2005: Ken Tachihara; Takeshi Uemura; Keiko Kashiwagi; Kazuei Igarashi
Excretion of putrescine and spermidine by the protein encoded by YKL174c (TPO5) in Saccharomyces cerevisiae.
The Journal of biological chemistry 2005;280(13):12637-42.
2005: Takeshi Uemura; Keiko Kashiwagi; Kazuei Igarashi
Uptake of putrescine and spermidine by Gap1p on the plasma membrane in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 2005;328(4):1028-33.
2005: Takeshi Uemura; Ken Tachihara; Hideyuki Tomitori; Keiko Kashiwagi; Kazuei Igarashi
Characteristics of the polyamine transporter TPO1 and regulation of its activity and cellular localization by phosphorylation.
The Journal of biological chemistry 2005;280(10):9646-52.
2005: Kuniko Kusama-Eguchi; Fumio Ikegami; Tadashi Kusama; A Suda; Y Ogawa; Kazuei Igarashi; K Watanabe
A rat model of neurolathyrism: repeated injection of L: -beta-ODAP induces the paraparesis of the hind legs.
Amino acids 2005;28(2):139-43.
2005: Kazuhiro Nishimura; Kaori Murozumi; Akira Shirahata; Myung Hee Park; Keiko Kashiwagi; Kazuei Igarashi
Independent roles of eIF5A and polyamines in cell proliferation.
The Biochemical journal 2005;385(Pt 3):779-85.
2004: Takashi Masuko; Ikuko Suzuki; Yasuo Kizawa; Kuniko Kusama-Eguchi; Kazuko Watanabe; Keiko Kashiwagi; Kazuei Igarashi; Tadashi Kusama
Monoamines directly inhibit N-methyl-D-aspartate receptors expressed in Xenopus oocytes in a voltage-dependent manner.
Neuroscience letters 2004;371(1):30-3.
2004: Kazuei Igarashi
[Polyamines in urine as markers of malignancy].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 11():150-3.
2004: Go Hirokawa; Hachiro Inokuchi; Hideko Kaji; Kazuei Igarashi; Akira Kaji
In vivo effect of inactivation of ribosome recycling factor - fate of ribosomes after unscheduled translation downstream of open reading frame.
Molecular microbiology 2004;54(4):1011-21.
2004: Madoka Yoshida; Keiko Kashiwagi; Ai Shigemasa; Shiho Taniguchi; Kaneyoshi Yamamoto; Hideki Makinoshima; Akira Ishihama; Kazuei Igarashi
A unifying model for the role of polyamines in bacterial cell growth, the polyamine modulon.
The Journal of biological chemistry 2004;279(44):46008-13.
2004: Kyohei Higashi; Kaori Yoshida; Kazuhiro Nishimura; Emi Momiyama; Keiko Kashiwagi; Senya Matsufuji; Akira Shirahata; Kazuei Igarashi
Structural and functional relationship among diamines in terms of inhibition of cell growth.
Journal of biochemistry 2004;136(4):533-9.
2004: Kuniko Kusama-Eguchi; Tadashi Kusama; Atsuhiro Suda; Takashi Masuko; Makoto Yamamoto; Fumio Ikegami; Kazuei Igarashi; Yu-Haey Kuo; Fernand Lambein; Kazuko Watanabe
Partial involvement of group I metabotropic glutamate receptors in the neurotoxicity of 3-N-oxalyl-L-2,3-diaminopropanoic acid (L-beta-ODAP).
Biological & pharmaceutical bulletin 2004;27(7):1052-8.
2004: Keiko Kashiwagi; Ikuko Tanaka; Maki Tamura; Hiromi Sugiyama; Tadashi Okawara; Masami Otsuka; Thomas N Sabado; Keith Williams; Kazuei Igarashi
Anthraquinone polyamines: novel channel blockers to study N-methyl-D-aspartate receptors.
The Journal of pharmacology and experimental therapeutics 2004;309(3):884-93.
2004: Elza Kimura; Kazuhiro Nishimura; Kaori Sakata; Seiji Oga; Keiko Kashiwagi; Kazuei Igarashi
Methotrexate differentially affects growth of suspension and adherent cells.
The international journal of biochemistry & cell biology 2004;36(5):814-25.
2004: Takeshi Uemura; Yuki Tomonari; Keiko Kashiwagi; Kazuei Igarashi
Uptake of GABA and putrescine by UGA4 on the vacuolar membrane in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 2004;315(4):1082-7.
2004: Waraporn Soksawatmaekhin; Aiko Kuraishi; Kaori Sakata; Keiko Kashiwagi; Kazuei Igarashi
Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli.
Molecular microbiology 2004;51(5):1401-12.
2004: Kyoko Yasumura; Isamu Sugimura; Kazuei Igarashi; Shizuko Kakinuma; Mayumi Nishimura; Masahiro Doi; Yoshiya Shimada
Altered expression of Tfg and Dap3 in Ikaros-defective T-cell lymphomas induced by X-irradiation in B6C3F1 mice.
British journal of haematology 2004;124(2):179-85.
2003: Kaori Sakata; Keiko Kashiwagi; Shahana Sharmin; Shiro Ueda; Yasubumi Irie; Noriyoshi Murotani; Kazuei Igarashi
Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients.
Biochemical and biophysical research communications 2003;305(1):143-9.
2003: Kaori Sakata; Keiko Kashiwagi; Shahana Sharmin; Shiro Ueda; Kazuei Igarashi
Acrolein produced from polyamines as one of the uraemic toxins.
Biochemical Society transactions 2003;31(2):371-4.
2003: Takashi Masuko; Kuniko Kusama-Eguchi; Kaori Sakata; Tadashi Kusama; Shigeyuki Chaki; Shigeru Okuyama; Keith Williams; Keiko Kashiwagi; Kazuei Igarashi
Polyamine transport, accumulation, and release in brain.
Journal of neurochemistry 2003;84(3):610-7.
2002: Feng Gao; Hideyuki Tomitori; Kazuei Igarashi; Toshiharu Horie
Correlation between methotrexate-induced intestinal damage and decrease in polyamine content.
Life sciences 2002;72(6):669-76.
2002: Hideyuki Tomitori; Mitsuru Nenoi; Kazuei Mita; Kazuhiro Daino; Kazuei Igarashi; Sachiko Ichimura
Functional characterization of the human spermidine/spermine N(1)-acetyltransferase gene promoter.
Biochimica et biophysica acta 2002;1579(2-3):180-4.
2002: V Samuel Raj; Christine Füll; Madoka Yoshida; Kaori Sakata; Keiko Kashiwagi; Akira Ishihama; Kazuei Igarashi
Decrease in cell viability in an RMF, sigma(38), and OmpC triple mutant of Escherichia coli.
Biochemical and biophysical research communications 2002;299(2):252-7.
2002: Kazunori Samata; Takehiro Yamagishi; Tomoko Ichihara; Kayoko Nanaumi; Tomotake Ikeda; Hisao Ikeya; Aiko Kuraishi; Shiro Nakaike; Keiko Kashiwagi; Kazuei Igarashi
Establishment and characterization of a mouse FM3A cell mutant resistant to topoisomerase II-inhibitor NC-190.
Cancer chemotherapy and pharmacology 2002;50(5):367-72.
2002: Megumi Sumino; Toshikazu Sekine; Nijsiri Ruangrungsi; Kazuei Igarashi; Fumio Ikegami
Ardisiphenols and other antioxidant principles from the fruits of Ardisia colorata.
Chemical & pharmaceutical bulletin 2002;50(11):1484-7.
2002: Madoka Yoshida; Keiko Kashiwagi; Gota Kawai; Akira Ishihama; Kazuei Igarashi
Polyamines enhance synthesis of the RNA polymerase sigma 38 subunit by suppression of an amber termination codon in the open reading frame.
The Journal of biological chemistry 2002;277(40):37139-46.
2002: Go Hirokawa; Michael C Kiel; Aiko Muto; Gota Kawai; Kazuei Igarashi; Hideko Kaji; Akira Kaji
Binding of ribosome recycling factor to ribosomes, comparison with tRNA.
The Journal of biological chemistry 2002;277(39):35847-52.
2002: Kyoko Yasumura; Kazuei Igarashi; Yoshimi Kakinuma
Promoter analysis of the sodium-responsive V-ATPase (ntp) operon in Enterococcus hirae.
Archives of microbiology 2002;178(3):172-9.
2002: Miyuki Kawano; Kazuei Igarashi; Ichiro Yamato; Yoshimi Kakinuma
Arginine residue at position 573 in Enterococcus hirae vacuolar-type ATPase NtpI subunit plays a crucial role in Na+ translocation.
The Journal of biological chemistry 2002;277(27):24405-10.
2002: Keiko Kashiwagi; Akane Innami; Risa Zenda; Hideyuki Tomitori; Kazuei Igarashi
The ATPase activity and the functional domain of PotA, a component of the sermidine-preferential uptake system in Escherichia coli.
The Journal of biological chemistry 2002;277(27):24212-9.
2002: Miyuki Kawano; Kazuei Igarashi; Yoshimi Kakinuma
Isolation of Enterococcus hirae mutant deficient in low-affinity potassium uptake at alkaline pH.
Bioscience, biotechnology, and biochemistry 2002;66(7):1597-600.
2002: Go Hirokawa; Michael C Kiel; Aiko Muto; Maria Selmer; V Samuel Raj; Anders Liljas; Kazuei Igarashi; Hideko Kaji; Akira Kaji
Post-termination complex disassembly by ribosome recycling factor, a functional tRNA mimic.
The EMBO journal 2002;21(9):2272-81.
2002: Kazuhiro Nishimura; Yuji Ohki; Tomomi Fukuchi-Shimogori; Kaori Sakata; Kan Saiga; Takanobu Beppu; Akira Shirahata; Keiko Kashiwagi; Kazuei Igarashi
Inhibition of cell growth through inactivation of eukaryotic translation initiation factor 5A (eIF5A) by deoxyspergualin.
The Biochemical journal 2002;363(Pt 3):761-8.
2002: Keiko Kashiwagi; Takashi Masuko; Christopher D Nguyen; Tomoko Kuno; Ikuko Tanaka; Kazuei Igarashi; Keith Williams
Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore.
Molecular pharmacology 2002;61(3):533-45.
2002: Kazunori Samata; Takehiro Yamagishi; Tomotake Ikeda; Aiko Kuraishi; Shiro Nakaike; Makoto Tanaka; Keiko Kashiwagi; Kazuei Igarashi
The topoisomerase II-inhibitor NC-190 reduces the level of thymidine kinase mRNA in murine tumor cells.
Research communications in molecular pathology and pharmacology 2002;111(1-4):77-87.
2002: Kazuhiro Nishimura; Fubito Nakatsu; Keiko Kashiwagi; Hiroshi Ohno; Takashi Saito; Kazuei Igarashi
Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(1):41-7.
2001: V S Raj; Hideyuki Tomitori; Masahiro Yoshida; A Apirakaramwong; Keiko Kashiwagi; K Takio; Akira Ishihama; Kazuei Igarashi
Properties of a revertant of Escherichia coli viable in the presence of spermidine accumulation: increase in L-glycerol 3-phosphate.
Journal of bacteriology 2001;183(15):4493-8.
2001: Masahiro Yoshida; Keiko Kashiwagi; Gota Kawai; Akira Ishihama; Kazuei Igarashi
Polyamine enhancement of the synthesis of adenylate cyclase at the translational level and the consequential stimulation of the synthesis of the RNA polymerase sigma 28 subunit.
The Journal of biological chemistry 2001;276(19):16289-95.
2001: Kazuei Igarashi; K Ito; Keiko Kashiwagi
Polyamine uptake systems in Escherichia coli.
Research in microbiology 2001;152(3-4):271-8.
2001: Shahana Sharmin; Kaori Sakata; Keiko Kashiwagi; Shiro Ueda; S Iwasaki; Akira Shirahata; Kazuei Igarashi
Polyamine cytotoxicity in the presence of bovine serum amine oxidase.
Biochemical and biophysical research communications 2001;282(1):228-35.
2001: Hideyuki Tomitori; Keiko Kashiwagi; T Asakawa; Yoshimi Kakinuma; A J Michael; Kazuei Igarashi
Multiple polyamine transport systems on the vacuolar membrane in yeast.
The Biochemical journal 2001;353(Pt 3):681-8.
2001: Miyuki Kawano; R Abuki; Kazuei Igarashi; Yoshimi Kakinuma
Potassium uptake with low affinity and high rate in Enterococcus hirae at alkaline pH.
Archives of microbiology 2001;175(1):41-5.
2000: Keiko Kashiwagi; Aiko Kuraishi; Hideyuki Tomitori; A Igarashi; Kazuhiro Nishimura; Akira Shirahata; Kazuei Igarashi
Identification of the putrescine recognition site on polyamine transport protein PotE.
The Journal of biological chemistry 2000;275(46):36007-12.
2000: S Hayashi; Kazuhiro Nishimura; Tomomi Fukuchi-Shimogori; Keiko Kashiwagi; Kazuei Igarashi
Increase in cap- and IRES-dependent protein synthesis by overproduction of translation initiation factor eIF4G.
Biochemical and biophysical research communications 2000;277(1):117-23.
2000: Kazuei Igarashi; Keiko Kashiwagi
Polyamines: mysterious modulators of cellular functions.
Biochemical and biophysical research communications 2000;271(3):559-64.
2000: M Ikegami; H Takahashi; Kazuei Igarashi; Yoshimi Kakinuma
Sodium ATPase and sodium/proton antiporter are not obligatory for sodium homeostasis of Enterococcus hirae at acid pH.
Bioscience, biotechnology, and biochemistry 2000;64(5):1088-92.
2000: Miyuki Kawano; R Abuki; Kazuei Igarashi; Yoshimi Kakinuma
Evidence for Na(+) influx via the NtpJ protein of the KtrII K(+) uptake system in Enterococcus hirae.
Journal of bacteriology 2000;182(9):2507-12.
2000: Kaori Sakata; Keiko Kashiwagi; Kazuei Igarashi
Properties of a polyamine transporter regulated by antizyme.
The Biochemical journal 2000;347 Pt 1():297-303.
1999: Kazuei Igarashi; Keiko Kashiwagi
Polyamine transport in bacteria and yeast.
The Biochemical journal 1999;344 Pt 3():633-42.
1999: Kazuhiro Nishimura; Kyoko Yasumura; Kazuei Igarashi; S Harashima; Yoshimi Kakinuma
Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by spt7p.
Yeast (Chichester, England) 1999;15(16):1711-7.
1999: A Apirakaramwong; Keiko Kashiwagi; V S Raj; Kaori Sakata; Yoshimi Kakinuma; Akira Ishihama; Kazuei Igarashi
Involvement of ppGpp, ribosome modulation factor, and stationary phase-specific sigma factor sigma(S) in the decrease in cell viability caused by spermidine.
Biochemical and biophysical research communications 1999;264(3):643-7.
1999: Kazuhiro Nishimura; Keiko Kashiwagi; Yoichi Matsuda; Olli A Jänne; Kazuei Igarashi
Gene structure and chromosomal localization of mouse S-adenosylmethionine decarboxylase.
Gene 1999;238(2):343-50.
1999: Takashi Masuko; Tomoko Kuno; Keiko Kashiwagi; Tadashi Kusama; Keith Williams; Kazuei Igarashi
Stimulatory and inhibitory properties of aminoglycoside antibiotics at N-methyl-D-aspartate receptors.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1026-33.
1999: Masahiro Yoshida; D Meksuriyen; Keiko Kashiwagi; Gota Kawai; Kazuei Igarashi
Polyamine stimulation of the synthesis of oligopeptide-binding protein (OppA). Involvement of a structural change of the Shine-Dalgarno sequence and the initiation codon aug in oppa mRNA.
The Journal of biological chemistry 1999;274(32):22723-8.
1999: M Ikegami; Miyuki Kawano; K Takase; Ichiro Yamato; Kazuei Igarashi; Yoshimi Kakinuma
Enterococcus hirae vacuolar ATPase is expressed in response to pH as well as sodium.
FEBS letters 1999;454(1-2):67-70.
1999: Yoshimi Kakinuma; Kazuei Igarashi
Isolation and properties of Enterococcus hirae mutants defective in the potassium/proton antiport system.
Journal of bacteriology 1999;181(13):4103-5.
1999: Takashi Masuko; Keiko Kashiwagi; Tomoko Kuno; ND Nguyen; AJ Pahk; J Fukuchi; Kazuei Igarashi; Keith Williams
A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein.
Molecular pharmacology 1999;55(6):957-69.
1999: Yoshimi Kakinuma; Kyoko Yasumura; Kazuei Igarashi
Potassium/proton antiport system is dispensable for growth of Enterococcus hirae at low pH.
Bioscience, biotechnology, and biochemistry 1999;63(5):875-8.
1999: Kazuhiro Nishimura; Kyoko Yasumura; Kazuei Igarashi; Yoshimi Kakinuma
Involvement of Spt7p in vacuolar polyphosphate level of Saccharomyces cerevisiae.
Biochemical and biophysical research communications 1999;257(3):835-8.
1999: Hideyuki Tomitori; Keiko Kashiwagi; Kaori Sakata; Yoshimi Kakinuma; Kazuei Igarashi
Identification of a gene for a polyamine transport protein in yeast.
The Journal of biological chemistry 1999;274(6):3265-7.
1999: F Antognoni; S Del Duca; Aiko Kuraishi; E Kawabe; Tomomi Fukuchi-Shimogori; Keiko Kashiwagi; Kazuei Igarashi
Transcriptional inhibition of the operon for the spermidine uptake system by the substrate-binding protein PotD.
The Journal of biological chemistry 1999;274(4):1942-8.
1999: E Arikado; H Ishihara; T Ehara; C Shibata; Hidekazu Saito; Tomohito Kakegawa; Kazuei Igarashi; Hiroshi Kobayashi
Enzyme level of enterococcal F1Fo-ATPase is regulated by pH at the step of assembly.
European journal of biochemistry / FEBS 1999;259(1-2):262-8.
1998: D Meksuriyen; Tomomi Fukuchi-Shimogori; Hideyuki Tomitori; Keiko Kashiwagi; Toshihiko Toida; Toshio Imanari; Gota Kawai; Kazuei Igarashi
Formation of a complex containing ATP, Mg2+, and spermine. Structural evidence and biological significance.
The Journal of biological chemistry 1998;273(47):30939-44.
1998: A Apirakaramwong; J Fukuchi; Keiko Kashiwagi; Yoshimi Kakinuma; E Ito; Akira Ishihama; Kazuei Igarashi
Enhancement of cell death due to decrease in Mg2+ uptake by OmpC (cation-selective porin) deficiency in ribosome modulation factor-deficient mutant.
Biochemical and biophysical research communications 1998;251(2):482-7.
1998: Keiko Kashiwagi; M H Tsuhako; Kaori Sakata; T Saisho; A Igarashi; S O da Costa; Kazuei Igarashi
Relationship between spontaneous aminoglycoside resistance in Escherichia coli and a decrease in oligopeptide binding protein.
Journal of bacteriology 1998;180(20):5484-8.
1998: Miyuki Kawano; Kazuei Igarashi; Yoshimi Kakinuma
The Na+-responsive ntp operon is indispensable for homeostatis of K+ and Na+ in Enterococcus hirae at limited proton potential.
Journal of bacteriology 1998;180(18):4942-5.
1998: Kazuhiro Nishimura; M Liisanantti; Y Muta; Keiko Kashiwagi; Akira Shirahata; M Jänne; K Kankare; Olli A Jänne; Kazuei Igarashi
Structure and activity of mouse S-adenosylmethionine decarboxylase gene promoters and properties of the encoded proteins.
The Biochemical journal 1998;332 ( Pt 3)():651-9.
1998: Keith Williams; AJ Pahk; Keiko Kashiwagi; Takashi Masuko; ND Nguyen; Kazuei Igarashi
The selectivity filter of the N-methyl-D-aspartate receptor: a tryptophan residue controls block and permeation of Mg2+.
Molecular pharmacology 1998;53(5):933-41.
1998: Kazuhiro Nishimura; Kazuei Igarashi; Yoshimi Kakinuma
Proton gradient-driven nickel uptake by vacuolar membrane vesicles of Saccharomyces cerevisiae.
Journal of bacteriology 1998;180(7):1962-4.
1997: Tomomi Fukuchi-Shimogori; I Ishii; Keiko Kashiwagi; H Mashiba; H Ekimoto; Kazuei Igarashi
Malignant transformation by overproduction of translation initiation factor eIF4G.
Cancer research 1997;57(22):5041-4.
1997: Kazuei Igarashi; A Shirahata; AJ Pahk; Keiko Kashiwagi; Keith Williams
Benzyl-polyamines: novel, potent N-methyl-D-aspartate receptor antagonists.
The Journal of pharmacology and experimental therapeutics 1997;283(2):533-40.
1997: Keiko Kashiwagi; AJ Pahk; Takashi Masuko; Kazuei Igarashi; Keith Williams
Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits.
Molecular pharmacology 1997;52(4):701-13.
1997: Kaori Sakata; Tomomi Fukuchi-Shimogori; Keiko Kashiwagi; Kazuei Igarashi
Identification of regulatory region of antizyme necessary for the negative regulation of polyamine transport.
Biochemical and biophysical research communications 1997;238(2):415-9.
1997: J Chao; Nikolaus Seiler; Jacques Renault; Keiko Kashiwagi; Takashi Masuko; Kazuei Igarashi; Keith Williams
N1-dansyl-spermine and N1-(n-octanesulfonyl)-spermine, novel glutamate receptor antagonists: block and permeation of N-methyl-D-aspartate receptors.
Molecular pharmacology 1997;51(5):861-71.
1997: Keiko Kashiwagi; S Shibuya; Hideyuki Tomitori; Aiko Kuraishi; Kazuei Igarashi
Excretion and uptake of putrescine by the PotE protein in Escherichia coli.
The Journal of biological chemistry 1997;272(10):6318-23.
1997: Kazuei Igarashi; T Saisho; M Yuguchi; Keiko Kashiwagi
Molecular mechanism of polyamine stimulation of the synthesis of oligopeptide-binding protein.
The Journal of biological chemistry 1997;272(7):4058-64.
1996: T Nozaki; Kazuhiro Nishimura; A J Michael; T Maruyama; Yoshimi Kakinuma; Kazuei Igarashi
A second gene encoding a putative serine/threonine protein kinase which enhances spermine uptake in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 1996;228(2):452-8.
1996: Keith Williams; J Chao; Keiko Kashiwagi; Takashi Masuko; Kazuei Igarashi
Activation of N-methyl-D-aspartate receptors by glycine: role of an aspartate residue in the M3-M4 loop of the NR1 subunit.
Molecular pharmacology 1996;50(4):701-8.
1996: T Shimogori; Keiko Kashiwagi; Kazuei Igarashi
Spermidine regulation of protein synthesis at the level of initiation complex formation of Met-tRNAi, mRNA and ribosomes.
Biochemical and biophysical research communications 1996;223(3):544-8.
1996: Keiko Kashiwagi; J Fukuchi; J Chao; Kazuei Igarashi; Keith Williams
An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons.
Molecular pharmacology 1996;49(6):1131-41.
1996: T Shimogori; T Suzuki; Keiko Kashiwagi; Yoshimi Kakinuma; Kazuei Igarashi
Enhancement of helicase activity and increase of eIF-4E phosphorylation in ornithine decarboxylase-overproducing cells.
Biochemical and biophysical research communications 1996;222(3):748-52.
1996: Keiko Kashiwagi; R Pistocchi; S Shibuya; S Sugiyama; K Morikawa; Kazuei Igarashi
Spermidine-preferential uptake system in Escherichia coli. Identification of amino acids involved in polyamine binding in PotD protein.
The Journal of biological chemistry 1996;271(21):12205-8.
1995: Keith Williams; Keiko Kashiwagi; J Fukuchi; Kazuei Igarashi
An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation.
Molecular pharmacology 1995;48(6):1087-98.
1995: Yoshimi Kakinuma; T Maruyama; T Nozaki; Y Wada; Y Ohsumi; Kazuei Igarashi
Cloning of the gene encoding a putative serine/threonine protein kinase which enhances spermine uptake in Saccharomyces cerevisiae.
Biochemical and biophysical research communications 1995;216(3):985-92.
1995: Keiko Kashiwagi; H Endo; Hiroshi Kobayashi; K Takio; Kazuei Igarashi
Spermidine-preferential uptake system in Escherichia coli. ATP hydrolysis by PotA protein and its association with membrane.
The Journal of biological chemistry 1995;270(43):25377-82.
1995: T Ogahara; M Ohno; M Takayama; Kazuei Igarashi; Hiroshi Kobayashi
Accumulation of glutamate by osmotically stressed Escherichia coli is dependent on pH.
Journal of bacteriology 1995;177(20):5987-90.
1995: J Fukuchi; Keiko Kashiwagi; M Yamagishi; Akira Ishihama; Kazuei Igarashi
Decrease in cell viability due to the accumulation of spermidine in spermidine acetyltransferase-deficient mutant of Escherichia coli.
The Journal of biological chemistry 1995;270(32):18831-5.
1995: Kazuei Igarashi; K Koga; Y He; T Shimogori; H Ekimoto; Keiko Kashiwagi; A Shirahata
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
Cancer research 1995;55(12):2615-9.
1995: Yoshimi Kakinuma; Kazuei Igarashi
Potassium/proton antiport system of growing Enterococcus hirae at high pH.
Journal of bacteriology 1995;177(8):2227-9.
1995: Y He; T Shimogori; Keiko Kashiwagi; A Shirahata; Kazuei Igarashi
Inhibition of cell growth by combination of alpha-difluoromethylornithine and an inhibitor of spermine synthase.
Journal of biochemistry 1995;117(4):824-9.
1995: Kazuei Igarashi; Keith Williams
Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors.
The Journal of pharmacology and experimental therapeutics 1995;272(3):1101-9.
1995: Yoshimi Kakinuma; Kazuei Igarashi
Electrogenic Na+ transport by Enterococcus hirae Na(+)-ATPase.
FEBS letters 1995;359(2-3):255-8.
1994: Yoshimi Kakinuma; Kazuei Igarashi
Purification and characterization of the catalytic moiety of vacuolar-type Na(+)-ATPase from Enterococcus hirae.
Journal of biochemistry 1994;116(6):1302-8.
1994: Itsuko Ishii; H Takada; K Terao; T Kakegawa; Kazuei Igarashi; S Hirose
Decrease in spermidine content during logarithmic phase of cell growth delays spore formation of Bacillus subtilis.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(7):925-31.
1994: T Maruyama; N Masuda; Yoshimi Kakinuma; Kazuei Igarashi
Polyamine-sensitive magnesium transport in Saccharomyces cerevisiae.
Biochimica et biophysica acta 1994;1194(2):289-95.
1994: T Suzuki; Y He; Keiko Kashiwagi; Y Murakami; S Hayashi; Kazuei Igarashi
Antizyme protects against abnormal accumulation and toxicity of polyamines in ornithine decarboxylase-overproducing cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8930-4.
1994: J Fukuchi; Keiko Kashiwagi; K Takio; Kazuei Igarashi
Properties and structure of spermidine acetyltransferase in Escherichia coli.
The Journal of biological chemistry 1994;269(36):22581-5.
1994: Y He; T Suzuki; Keiko Kashiwagi; Kazuei Igarashi
Antizyme delays the restoration by spermine of growth of polyamine-deficient cells through its negative regulation of polyamine transport.
Biochemical and biophysical research communications 1994;203(1):608-14.
1994: T Ohyama; Kazuei Igarashi; Hiroshi Kobayashi
Physiological role of the chaA gene in sodium and calcium circulations at a high pH in Escherichia coli.
Journal of bacteriology 1994;176(14):4311-5.
1994: K Terao; S Ohmori; Kazuei Igarashi; I Ohtani; M F Watanabe; Kenichi Harada; Emiko Ito; M Watanabe
Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans.
Toxicon : official journal of the International Society on Toxinology 1994;32(7):833-43.
1994: Keiko Kashiwagi; R Watanabe; Kazuei Igarashi
Involvement of ribonuclease III in the enhancement of expression of the speF-potE operon encoding inducible ornithine decarboxylase and polyamine transport protein.
Biochemical and biophysical research communications 1994;200(1):591-7.
1994: Y He; T Suzuki; Keiko Kashiwagi; K Kusama-Eguchi; A Shirahata; Kazuei Igarashi
Correlation between the inhibition of cell growth by bis(ethyl)polyamine analogues and the decrease in the function of mitochondria.
European journal of biochemistry / FEBS 1994;221(1):391-8.
1994: M Takayama; T Ohyama; Kazuei Igarashi; Hiroshi Kobayashi
Escherichia coli cad operon functions as a supplier of carbon dioxide.
Molecular microbiology 1994;11(5):913-8.
1993: Y He; Keiko Kashiwagi; J Fukuchi; K Terao; A Shirahata; Kazuei Igarashi
Correlation between the inhibition of cell growth by accumulated polyamines and the decrease of magnesium and ATP.
European journal of biochemistry / FEBS 1993;217(1):89-96.
1993: Yoshimi Kakinuma; S Kakinuma; K Takase; K Konishi; Kazuei Igarashi; Ichiro Yamato
A gene encoding the 16-kDa proteolipid subunit of Enterococcus hirae Na(+)-ATPase complex.
Biochemical and biophysical research communications 1993;195(2):1063-9.
1993: Keiko Kashiwagi; S Miyamoto; E Nukui; Hiroshi Kobayashi; Kazuei Igarashi
Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli.
The Journal of biological chemistry 1993;268(26):19358-63.
1993: T Suzuki; Y Sadakata; Keiko Kashiwagi; K Hoshino; Yoshimi Kakinuma; A Shirahata; Kazuei Igarashi
Overproduction of S-adenosylmethionine decarboxylase in ethylglyoxal-bis(guanylhydrazone)-resistant mouse FM3A cells.
European journal of biochemistry / FEBS 1993;215(2):247-53.
1993: T Suzuki; C Shibata; Atsushi Yamaguchi; Kazuei Igarashi; Hiroshi Kobayashi
Complementation of an Enterococcus hirae (Streptococcus faecalis) mutant in the alpha subunit of the H(+)-ATPase by cloned genes from the same and different species.
Molecular microbiology 1993;9(1):111-8.
1993: T Suzuki; Keiko Kashiwagi; Kazuei Igarashi
Polyamine regulation of S-adenosylmethionine decarboxylase synthesis through the 5'-untranslated region of its mRNA.
Biochemical and biophysical research communications 1993;192(2):627-34.
1993: Kazuei Igarashi
[Role of polyamines in cell proliferation and differentiation].
Seikagaku. The Journal of Japanese Biochemical Society 1993;65(2):86-104.
1993: R Pistocchi; Keiko Kashiwagi; S Miyamoto; E Nukui; Y Sadakata; Hiroshi Kobayashi; Kazuei Igarashi
Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.
The Journal of biological chemistry 1993;268(1):146-52.
1993: S Miyamoto; Keiko Kashiwagi; K Ito; S Watanabe; Kazuei Igarashi
Estimation of polyamine distribution and polyamine stimulation of protein synthesis in Escherichia coli.
Archives of biochemistry and biophysics 1993;300(1):63-8.
1992: T Ohyama; R Imaizumi; Kazuei Igarashi; Hiroshi Kobayashi
Escherichia coli is able to grow with negligible sodium ion extrusion activity at alkaline pH.
Journal of bacteriology 1992;174(23):7743-9.
1992: J Fukuchi; Keiko Kashiwagi; K Kusama-Eguchi; K Terao; A Shirahata; Kazuei Igarashi
Mechanism of the inhibition of cell growth by N1,N12-bis(ethyl)spermine.
European journal of biochemistry / FEBS 1992;209(2):689-96.
1992: C Shibata; T Ehara; K Tomura; Kazuei Igarashi; Hiroshi Kobayashi
Gene structure of Enterococcus hirae (Streptococcus faecalis) F1F0-ATPase, which functions as a regulator of cytoplasmic pH.
Journal of bacteriology 1992;174(19):6117-24.
1992: Keiko Kashiwagi; A Miyaji; S Ikeda; T Tobe; C Sasakawa; Kazuei Igarashi
Increase of sensitivity to aminoglycoside antibiotics by polyamine-induced protein (oligopeptide-binding protein) in Escherichia coli.
Journal of bacteriology 1992;174(13):4331-7.
1992: Yoshimi Kakinuma; N Masuda; Kazuei Igarashi
Proton potential-dependent polyamine transport by vacuolar membrane vesicles of Saccharomyces cerevisiae.
Biochimica et biophysica acta 1992;1107(1):126-30.
1992: Keiko Kashiwagi; S Miyamoto; F Suzuki; Hiroshi Kobayashi; Kazuei Igarashi
Excretion of putrescine by the putrescine-ornithine antiporter encoded by the potE gene of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4529-33.
1992: T Ohyama; S Mugikura; M Nishikawa; Kazuei Igarashi; Hiroshi Kobayashi
Osmotic adaptation of Escherichia coli with a negligible proton motive force in the presence of carbonyl cyanide m-chlorophenylhydrazone.
Journal of bacteriology 1992;174(9):2922-8.
1992: M Furutani; Keiko Kashiwagi; K Ito; Y Endo; Kazuei Igarashi
Comparison of the modes of action of a Vero toxin (a Shiga-like toxin) from Escherichia coli, of ricin, and of alpha-sarcin.
Archives of biochemistry and biophysics 1992;293(1):140-6.
1992: H Kumagai; R Kon; T Hoshino; T Aramaki; M Nishikawa; S Hirose; Kazuei Igarashi
Purification and properties of a decapping enzyme from rat liver cytosol.
Biochimica et biophysica acta 1992;1119(1):45-51.
1991: T Furuchi; Keiko Kashiwagi; Hiroshi Kobayashi; Kazuei Igarashi
Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.
The Journal of biological chemistry 1991;266(31):20928-33.
1991: Keiko Kashiwagi; T Suzuki; F Suzuki; T Furuchi; Hiroshi Kobayashi; Kazuei Igarashi
Coexistence of the genes for putrescine transport protein and ornithine decarboxylase at 16 min on Escherichia coli chromosome.
The Journal of biological chemistry 1991;266(31):20922-7.
1991: S Watanabe; K Kusama-Eguchi; Hiroshi Kobayashi; Kazuei Igarashi
Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.
The Journal of biological chemistry 1991;266(31):20803-9.
1991: Yoshimi Kakinuma; Kazuei Igarashi; K Konishi; Ichiro Yamato
Primary structure of the alpha-subunit of vacuolar-type Na(+)-ATPase in Enterococcus hirae. Amplification of a 1000-bp fragment by polymerase chain reaction.
FEBS letters 1991;292(1-2):64-8.
1991: Keiko Kashiwagi; K Ito; Kazuei Igarashi
Spermidine regulation of ornithine decarboxylase synthesis by a GC-rich sequence of the 5'-untranslated region.
Biochemical and biophysical research communications 1991;178(3):815-22.
1991: K Kusama-Eguchi; M Irisawa; S Watanabe; K Watanabe; Kazuei Igarashi
Increase in fidelity of rat liver Ile-tRNA formation by both spermine and the aminoacyl-tRNA synthetase complex.
Archives of biochemistry and biophysics 1991;288(2):495-9.
1991: K Kusama-Eguchi; S Watanabe; M Irisawa; K Watanabe; Kazuei Igarashi
Correlation between spermine stimulation of rat liver Ile-tRNA formation and structural change of the acceptor stem by spermine.
Biochemical and biophysical research communications 1991;177(2):745-50.
1991: T Kakegawa; Y Guo; Y Chiba; T Miyazaki; M Nakamura; S Hirose; Z N Canellakis; Kazuei Igarashi
Effect of acetylpolyamines on in vitro protein synthesis and on the growth of a polyamine-requiring mutant of Escherichia coli.
Journal of biochemistry 1991;109(4):627-31.
1990: Keiko Kashiwagi; N Hosokawa; T Furuchi; Hiroshi Kobayashi; C Sasakawa; M Yoshikawa; Kazuei Igarashi
Isolation of polyamine transport-deficient mutants of Escherichia coli and cloning of the genes for polyamine transport proteins.
The Journal of biological chemistry 1990;265(34):20893-7.
1990: Kazuei Igarashi; Keiko Kashiwagi; J Fukuchi; Y Isobe; S Otomo; A Shirahata
Spermine-like functions of N1, N12-bis(ethyl)spermine: stimulation of protein synthesis and cell growth and inhibition of gastric ulceration.
Biochemical and biophysical research communications 1990;172(2):715-20.
1990: Yoshimi Kakinuma; Kazuei Igarashi
Some features of the Streptococcus faecalis Na(+)-ATPase resemble those of the vacuolar-type ATPases.
FEBS letters 1990;271(1-2):97-101.
1990: Yoshimi Kakinuma; Kazuei Igarashi
Release of the component of Streptococcus faecalis Na(+)-ATPase from the membranes.
FEBS letters 1990;271(1-2):102-5.
1990: K Ito; Keiko Kashiwagi; S Watanabe; T Kameji; S Hayashi; Kazuei Igarashi
Influence of the 5'-untranslated region of ornithine decarboxylase mRNA and spermidine on ornithine decarboxylase synthesis.
The Journal of biological chemistry 1990;265(22):13036-41.
1990: S Mugikura; M Nishikawa; Kazuei Igarashi; Hiroshi Kobayashi
Maintenance of a neutral cytoplasmic pH is not obligatory for growth of Escherichia coli and Streptococcus faecalis at an alkaline pH.
Journal of biochemistry 1990;108(1):86-91.
1990: Keiko Kashiwagi; Y Yamaguchi; Y Sakai; Hiroshi Kobayashi; Kazuei Igarashi
Identification of the polyamine-induced protein as a periplasmic oligopeptide binding protein.
The Journal of biological chemistry 1990;265(15):8387-91.
1990: Z Peng; K Kusama-Eguchi; S Watanabe; K Ito; K Watanabe; Y Nomoto; Kazuei Igarashi
Responsibility of tRNA(Ile) for spermine stimulation of rat liver Ile-tRNA formation.
Archives of biochemistry and biophysics 1990;279(1):138-45.
1990: Yoshimi Kakinuma; Kazuei Igarashi
Mutants of Streptococcus faecalis sensitive to alkaline pH lack Na(+)-ATPase.
Journal of bacteriology 1990;172(4):1732-5.
1990: K Ito; Kazuei Igarashi
Polyamine regulation of the synthesis of thymidine kinase in bovine lymphocytes.
Archives of biochemistry and biophysics 1990;278(1):277-83.
1990: Yoshimi Kakinuma; Kazuei Igarashi
Amplification of the Na+-ATPase of Streptococcus faecalis at alkaline pH.
FEBS letters 1990;261(1):135-8.
1990: M Furutani; K Ito; Y Oku; Y Takeda; Kazuei Igarashi
Demonstration of RNA N-glycosidase activity of a Vero toxin (VT2 variant) produced by Escherichia coli O91:H21 from a patient with the hemolytic uremic syndrome.
Microbiology and immunology 1990;34(4):387-92.
1989: Yoshimi Kakinuma; Kazuei Igarashi
Sodium-translocating adenosine triphosphatase in Streptococcus faecalis.
Journal of bioenergetics and biomembranes 1989;21(6):679-92.
1989: Kazuei Igarashi; Keiko Kashiwagi; Hiroshi Kobayashi; R Ohnishi; T Kakegawa; A Nagasu; S Hirose
Effect of polyamines on mitochondrial F1-ATPase catalyzed reactions.
Journal of biochemistry 1989;106(2):294-8.
1989: T Kakegawa; S Hirose; E Kimura; H Aihara; Y Isobe; Kazuei Igarashi
Effect of polyamine related tetraamines on anti-ulcerogenic activity and anti-H+,K+-ATPase activity.
Research communications in chemical pathology and pharmacology 1989;64(3):395-406.
1989: Y Sakamaki; K Terao; E Ito; Keiko Kashiwagi; Kazuei Igarashi
Swelling of the Golgi apparatus and decrease of galactosyltransferase in polyamine-deficient bovine lymphocytes and epithelium of mouse small intestine.
Biochemical pharmacology 1989;38(7):1083-9.
1989: T Ogasawara; K Ito; Kazuei Igarashi
Effect of polyamines on globin synthesis in a rabbit reticulocyte polyamine-free protein synthetic system.
Journal of biochemistry 1989;105(2):164-7.
1989: K Terao; Emiko Ito; Y Kakinuma; Kazuei Igarashi; M Kobayashi; Y Ohizumi; T Yasumoto
Histopathological studies on experimental marine toxin poisoning--4. Pathogenesis of experimental maitotoxin poisoning.
Toxicon : official journal of the International Society on Toxinology 1989;27(9):979-88.
1989: Keiko Kashiwagi; Y Sakai; Kazuei Igarashi
Polyamine stimulation of ribosomal synthesis and activity in a polyamine-dependent mutant of Escherichia coli.
Archives of biochemistry and biophysics 1989;268(1):379-87.
1988: Shigeru Ohmori; T Misaizu; Mitsukazu Kitada; H Kitagawa; Kazuei Igarashi; S Hirose; Y Kanakubo
Polyamine lowered the hepatic lipid peroxide level in rats.
Research communications in chemical pathology and pharmacology 1988;62(2):235-49.
1988: Yoshimi Kakinuma; Kazuei Igarashi
Active potassium extrusion regulated by intracellular pH in Streptococcus faecalis.
The Journal of biological chemistry 1988;263(28):14166-70.
1988: Yoshimi Kakinuma; K Hoshino; Kazuei Igarashi
Characterization of the inducible polyamine transporter in bovine lymphocytes.
European journal of biochemistry / FEBS 1988;176(2):409-14.
1988: Keiko Kashiwagi; Kazuei Igarashi
Adjustment of polyamine contents in Escherichia coli.
Journal of bacteriology 1988;170(7):3131-5.
1988: S Nakaike; Keiko Kashiwagi; K Terao; K Iio; Kazuei Igarashi
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Japanese journal of cancer research : Gann 1988;79(4):501-8.
1988: T Kakegawa; K Takamiya; T Ogawa; Y Hayashi; S Hirose; M Niitsu; Keijiro Samejima; Kazuei Igarashi
Effect of various polyamine analogs on in vitro polypeptide synthesis.
Archives of biochemistry and biophysics 1988;261(2):250-6.
1988: T Ogasawara; K Ito; Kazuei Igarashi; T Yutsudo; N Nakabayashi; Y Takeda
Inhibition of protein synthesis by a Vero toxin (VT2 or Shiga-like toxin II) produced by Escherichia coli O157:H7 at the level of elongation factor 1-dependent aminoacyl-tRNA binding to ribosomes.
Microbial pathogenesis 1988;4(2):127-35.
1988: K Terao; Emiko Ito; Y Sakamaki; Kazuei Igarashi; A Yokoyama; T Yasumoto
Histopathological studies of experimental marine toxin poisoning. II. The acute effects of maitotoxin on the stomach, heart and lymphoid tissues in mice and rats.
Toxicon : official journal of the International Society on Toxinology 1988;26(4):395-402.
1988: Kazuei Igarashi; K Ito; Y Sakai; T Ogasawara; Keiko Kashiwagi
Regulation of protein synthesis by polyamines.
Advances in experimental medicine and biology 1988;250():315-30.
1987: Yoshimi Kakinuma; Y Sakamaki; K Ito; E J Cragoe; Kazuei Igarashi
Relationship among activation of the Na+/H+ antiporter, ornithine decarboxylase induction, and DNA synthesis.
Archives of biochemistry and biophysics 1987;259(1):171-8.
1987: S Fujimoto; R D Shrestha; M Ohta; Kazuei Igarashi; M Kokubun; K Okui; M Fujita; T Taguchi
[Antitumor efficacy of polyamine antimetabolites and mitomycin C under polyamine-free diet].
Gan to kagaku ryoho. Cancer & chemotherapy 1987;14(10):2930-5.