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Louis Ignarro
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36
Napoli, Claudio
34
Buga, Georgette
24
de Nigris, Filomena
21
Chaudhuri, Gautam
21
Williams-Ignarro, Sharon
16
Sica, Vincenzo
16
Fukuto, Jon
14
Lerman, Lilach
11
Buckberg, Gerald
10
Fiorito, Carmela
10
Hayashi, Toshio
10
Iguchi, Akihisa
9
Crimi, Emanuele
9
D'Armiento, Francesco
9
Rogers, NE
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All Publications
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2009: Napoli Claudio; Ignarro Louis J
Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases.
Archives of pharmacal research 2009;32(8):1103-8.
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2009: Ignarro Louis J
Preface to this special journal issue on nitric oxide chemistry and biology.
Archives of pharmacal research 2009;32(8):1099-101.
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2009: Crimi Ettore; Ignarro Louis J; Cacciatore Francesco; Napoli Claudio
Mechanisms by which exercise training benefits patients with heart failure.
Nature reviews. Cardiology 2009;6(4):292-300.
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2009: Strauch Berish; Herman Charles; Dabb Richard; Ignarro Louis J; Pilla Arthur A
Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery.
Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 2009;29(2):135-43.
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2009: d'Emmanuele di Villa Bianca Roberta; Sorrentino Raffaella; Maffia Pasquale; Mirone Vincenzo; Imbimbo Ciro; Fusco Ferdinando; De Palma Raffaele; Ignarro Louis J; Cirino Giuseppe
Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4513-8.
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2008: Napoli Claudio; Bruzzese Giuseppe; Ignarro Louis J; Crimi Ettore; de Nigris Filomena; Williams-Ignarro Sharon; Libardi Sabina; Sommese Linda; Fiorito Carmela; Mancini Francesco P; Cacciatore Francesco; Liguori Antonio
Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension.
American heart journal 2008;156(6):1154.e1-8.
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2008: Napoli Claudio; William-Ignarro Sharon; Byrns Russell; Balestrieri Maria Luisa; Crimi Ettore; Farzati Bartolomeo; Mancini Francesco P; de Nigris Filomena; Matarazzo Angelo; D'Amora Maurizio; Abbondanza Ciro; Fiorito Carmela; Giovane Alfonso; Florio Anna; Varricchio Ettore; Palagiano Antonio; Minucci Pellegrino Biagio; Tecce Mario Felice; Giordano Antonio; Pavan Antonio; Ignarro Louis J
Therapeutic targeting of the stem cell niche in experimental hindlimb ischemia.
Nature clinical practice. Cardiovascular medicine 2008;5(9):571-9.
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2008: Ignarro Louis; Heber David; Henig Y Steven; Bejar Ezra
Herbalife nutritional products and liver injury revisited.
Journal of hepatology 2008;49(2):291-3; author reply 293-4.
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2008: de Nigris Filomena; Mancini Francesco Paolo; Balestrieri Maria Luisa; Byrns Russell; Fiorito Carmela; Williams-Ignarro Sharon; Palagiano Antonio; Crimi Ettore; Ignarro Louis J; Napoli Claudio
Therapeutic dose of nebivolol, a nitric oxide-releasing beta-blocker, reduces atherosclerosis in cholesterol-fed rabbits.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(1):57-63.
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2008: Salvatore Paola; Casamassimi Amelia; Sommese Linda; Fiorito Carmela; Ciccodicola Alfredo; Rossiello Raffaele; Avallone Bice; Grimaldi Vincenzo; Costa Valerio; Rienzo Monica; Colicchio Roberta; Williams-Ignarro Sharon; Pagliarulo Caterina; Prudente Maria Evelina; Abbondanza Ciro; Lamberti Florentia; Baroni Adone; Buommino Elisabetta; Farzati Bartolomeo; Tufano Maria Antonietta; Ignarro Louis Joseph; Napoli Claudio
Detrimental effects of Bartonella henselae are counteracted by L-arginine and nitric oxide in human endothelial progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(27):9427-32.
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2008: Wei Liu Hua; Yang Yang; Wu Guoyao; Ignarro Louis J
IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells.
American journal of physiology. Cell physiology 2008;294(5):C1198-205.
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2008: de Nigris Filomena; Rossiello Raffaele; Schiano Concetta; Arra Claudio; Williams-Ignarro Sharon; Barbieri Antonio; Lanza Alessandro; Balestrieri Antonio; Giuliano Maria Teresa; Ignarro Louis J; Napoli Claudio
Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis.
Cancer research 2008;68(6):1797-808.
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2008: Liguori Antonio; Fiorito Carmela; Balestrieri Maria Luisa; Crimi Ettore; Bruzzese Giuseppe; Williams-Ignarro Sharon; D'Amora Maurizio; Sommese Linda; Grimaldi Vincenzo; Minucci Pellegrino Biagio; Giovane Alfonso; Farzati Bartolomeo; Ignarro Louis J; Napoli Claudio
Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease.
European journal of haematology 2008;80(3):258-64.
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2008: Selvendiran Karuppaiyah; Bratasz Anna; Tong Liyue; Ignarro Louis J; Kuppusamy Periannan
NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts.
Cell cycle (Georgetown, Tex.) 2008;7(1):81-8.
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2008: Ignarro Louis J
Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol.
Cardiovascular therapeutics 2008;26(2):115-34.
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2008: Bratasz Anna; Selvendiran Karuppaiyah; Wasowicz Tomasz; Bobko Andrey; Khramtsov Valery V; Ignarro Louis J; Kuppusamy Periannan
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.
Journal of translational medicine 2008;6():9.
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2007: Crimi E; Ignarro L J; Napoli C
Microcirculation and oxidative stress.
Free radical research 2007;41(12):1364-75.
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2007: Liguori A; D'Armiento F P; Palagiano A; Balestrieri M L; Williams-Ignarro S; de Nigris F; Lerman L O; D'Amora M; Rienzo M; Fiorito C; Ignarro L J; Palinski W; Napoli C
Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids.
BJOG : an international journal of obstetrics and gynaecology 2007;114(12):1547-56.
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2007: Parinandi Narasimham L; Sharma Ashish; Eubank Timothy D; Kaufman Bruce F; Kutala Vijay Kumar; Marsh Clay B; Ignarro Louis J; Kuppusamy Periannan
Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.
Antioxidants & redox signaling 2007;9(11):1837-49.
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2007: de Nigris Filomena; Balestrieri Maria Luisa; Williams-Ignarro Sharon; D'Armiento Francesco P; Lerman Lilach O; Byrns Russell; Crimi Ettore; Palagiano Antonio; Fatigati Gennaro; Ignarro Louis J; Napoli Claudio
Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways.
Journal of cardiovascular pharmacology 2007;50(4):424-33.
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2007: Ignarro Louis J
Heart mtNOS, a key mediator of oxidative injury in ischemia/reperfusion.
Journal of molecular and cellular cardiology 2007;43(4):409-10.
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2007: de Nigris Filomena; Balestrieri Maria Luisa; Williams-Ignarro Sharon; D'Armiento Francesco P; Fiorito Carmela; Ignarro Louis J; Napoli Claudio
The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;17(1):50-4.
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2007: Napoli Claudio; Maione Ciro; Schiano Concetta; Fiorito Carmela; Ignarro Louis J
Bone marrow cell-mediated cardiovascular repair: potential of combined therapies.
Trends in molecular medicine 2007;13(7):278-86.
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2007: Bode-Böger Stefanie M; Scalera Fortunato; Ignarro Louis J
The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio.
Pharmacology & therapeutics 2007;114(3):295-306.
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2007: de Nigris Filomena; Williams-Ignarro Sharon; Sica Vincenzo; D'Armiento Francesco P; Lerman Lilach O; Byrns Russell E; Sica Giacomo; Fiorito Carmela; Ignarro Louis J; Napoli Claudio
Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb.
International journal of cardiology 2007;117(2):238-43.
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2007: Napoli Claudio; Ignarro Louis J
Polymorphisms in endothelial nitric oxide synthase and carotid artery atherosclerosis.
Journal of clinical pathology 2007;60(4):341-4.
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2007: Hayashi Toshio; Juliet Packiasamy A R; Miyazaki Asaka; Ignarro Louis J; Iguchi Akihisa
High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis.
Biochimica et biophysica acta 2007;1772(3):364-72.
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2007: Baker Andrew H; Sica Vincenzo; Work Lorraine M; Williams-Ignarro Sharon; de Nigris Filomena; Lerman Lilach O; Casamassimi Amelia; Lanza Alessandro; Schiano Concetta; Rienzo Monica; Ignarro Louis J; Napoli Claudio
Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3597-602.
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2007: Osawa Masako; Hayashi Toshio; Nomura Hideki; Funami Jun; Miyazaki Asaka; Ignarro Louis J; Iguchi Akihisa
Nitric oxide (NO) is a new clinical biomarker of survival in the elderly patients and its efficacy might be nearly equal to albumin.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2007;16(1):157-63.
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2007: Ohta Fumio; Takagi Tomo; Sato Hiroyuki; Ignarro Louis J
Low-dose L-arginine administration increases microperfusion of hindlimb muscle without affecting blood pressure in rats.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1407-11.
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2007: Napoli Claudio; Stanley William C; Ignarro Louis J
Nutrition and cardiovascular disease: putting a pathogenic framework into focus.
Cardiovascular research 2007;73(2):253-6.
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2007: de Nigris Filomena; Williams-Ignarro Sharon; Sica Vincenzo; Lerman Lilach O; D'Armiento Francesco P; Byrns Russell E; Casamassimi Amelia; Carpentiero Daniela; Schiano Concetta; Sumi Daigo; Fiorito Carmela; Ignarro Louis J; Napoli Claudio
Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis.
Cardiovascular research 2007;73(2):414-23.
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2007: Ignarro Louis J; Balestrieri Maria Luisa; Napoli Claudio
Nutrition, physical activity, and cardiovascular disease: an update.
Cardiovascular research 2007;73(2):326-40.
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2007: Napoli Claudio; Balestrieri Antonio; Ignarro Louis J
Therapeutic approaches in vascular repair induced by adult bone marrow cells and circulating progenitor endothelial cells.
Current pharmaceutical design 2007;13(31):3245-51.
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2006: Sica Vincenzo; Williams-Ignarro Sharon; de Nigris Filomena; D'Armiento Francesco P; Lerman Lilach O; Balestrieri Maria Luisa; Maione Ciro; Palagiano Antonio; Rossiello Luigi; Ignarro Louis J; Napoli Claudio
Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb.
Cell cycle (Georgetown, Tex.) 2006;5(24):2903-8.
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2006: Napoli Claudio; de Nigris Filomena; Williams-Ignarro Sharon; Pignalosa Orlando; Sica Vincenzo; Ignarro Louis J
Nitric oxide and atherosclerosis: an update.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;15(4):265-79.
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2006: Hayashi Toshio; Matsui-Hirai Hisako; Miyazaki-Akita Asaka; Fukatsu Akiko; Funami Jun; Ding Qun-Fang; Kamalanathan Sumitra; Hattori Yuichi; Ignarro Louis J; Iguchi Akihisa
Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):17018-23.
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2006: de Nigris Filomena; Williams-Ignarro Sharon; Botti Chiara; Sica Vincenzo; Ignarro Louis J; Napoli Claudio
Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;15(3):259-63.
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2006: Buga Georgette M; Frank Joy S; Mottino Giuliano A; Hendizadeh Michael; Hakhamian Ashkan; Tillisch Jan H; Reddy Srinivasa T; Navab Mohamad; Anantharamaiah G M; Ignarro Louis J; Fogelman Alan M
D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet.
Journal of lipid research 2006;47(10):2148-60.
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2006: Pryor William A; Houk Kendall N; Foote Christopher S; Fukuto Jon M; Ignarro Louis J; Squadrito Giuseppe L; Davies Kelvin J A
Free radical biology and medicine: it's a gas, man!
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(3):R491-511.
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2006: Ignarro Louis J; Byrns Russell E; Sumi Daigo; de Nigris Filomena; Napoli Claudio
Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;15(2):93-102.
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2006: Rodríguez Larissa V; Alfonso Zeni; Zhang Rong; Leung Joanne; Wu Benjamin; Ignarro Louis J
Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):12167-72.
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2006: Matteo M; Cicinelli E; Baldini D; Cho Y S; Ignarro L J; Vitarelli A; Boffoli D; Greco P
Influence of human menopausal gonadotrophin treatment on testicular blood flow and on seminal plasma nitric oxide levels in infertile males.
International journal of andrology 2006;29(4):441-5.
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2006: Crimi Ettore; Sica Vincenzo; Slutsky Arthur S; Zhang Haibo; Williams-Ignarro Sharon; Ignarro Louis J; Napoli Claudio
Role of oxidative stress in experimental sepsis and multisystem organ dysfunction.
Free radical research 2006;40(7):665-72.
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2006: Pantuck Allan J; Leppert John T; Zomorodian Nazy; Aronson William; Hong Jenny; Barnard R James; Seeram Navindra; Liker Harley; Wang Hejing; Elashoff Robert; Heber David; Aviram Michael; Ignarro Louis; Belldegrun Arie
Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):4018-26.
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2006: Napoli Claudio; Williams-Ignarro Sharon; de Nigris Filomena; Lerman Lilach O; D'Armiento Francesco P; Crimi Ettore; Byrns Russell E; Casamassimi Amelia; Lanza Alessandro; Gombos Fernando; Sica Vincenzo; Ignarro Louis J
Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10479-84.
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2006: Bratasz Anna; Weir Nathan M; Parinandi Narasimham L; Zweier Jay L; Sridhar Rajagopalan; Ignarro Louis J; Kuppusamy Periannan
Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3914-9.
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2006: Crimi Ettore; Sica Vincenzo; Williams-Ignarro Sharon; Zhang Haibo; Slutsky Arthur S; Ignarro Louis J; Napoli Claudio
The role of oxidative stress in adult critical care.
Free radical biology & medicine 2006;40(3):398-406.
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2005: Napoli Claudio; Williams-Ignarro Sharon; de Nigris Filomena; de Rosa Gaetano; Lerman Lilach O; Farzati Bartolomeo; Matarazzo Angelo; Sica Giacomo; Botti Chiara; Fiore Andrea; Byrns Russell E; Sumi Daigo; Sica Vincenzo; Ignarro Louis J
Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17202-6.
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2005: Hayashi Toshio; Juliet Packiasamy A R; Matsui-Hirai Hisako; Miyazaki Asaka; Fukatsu Akiko; Funami Jun; Iguchi Akihisa; Ignarro Louis J
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13681-6.
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2005: de Nigris Filomena; Williams-Ignarro Sharon; Lerman Lilach O; Crimi Ettore; Botti Chiara; Mansueto Gelsomina; D'Armiento Francesco P; De Rosa Gaetano; Sica Vincenzo; Ignarro Louis J; Napoli Claudio
Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4896-901.
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2005: Sumi Daigo; Ignarro Louis J
Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1.
Biochemical and biophysical research communications 2005;328(1):165-72.
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2005: Garbán Hermes J; Márquez-Garbán Diana C; Pietras Richard J; Ignarro Louis J
Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: regulation of estrogen-dependent gene transcription.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2632-6.
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2005: Ignarro Louis J; Napoli Claudio
Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.
Current diabetes reports 2005;5(1):17-23.
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2005: Bucci Mariarosaria; Roviezzo Fiorentina; Posadas Inmaculada; Yu Jun; Parente Luca; Sessa William C; Ignarro Louis J; Cirino Giuseppe
Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):904-8.
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2005: Ignarro Louis J
Nitric oxide.
Current topics in medicinal chemistry 2005;5(7):595.
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2004: Ignarro Louis J
Experimental evidences of nitric oxide-dependent vasodilatory activity of nebivolol, a third-generation beta-blocker.
Blood pressure. Supplement 2004;1():2-16.
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2004: Olcott Angelica P; Tocco Georges; Tian Jide; Zekzer Dan; Fukuto Jon; Ignarro Louis; Kaufman Daniel L
A salen-manganese catalytic free radical scavenger inhibits type 1 diabetes and islet allograft rejection.
Diabetes 2004;53(10):2574-80.
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2004: Hayashi Toshio; Rani P Juliet Arockia; Fukatsu Akiko; Matsui-Hirai Hisako; Osawa Masako; Miyazaki Asaka; Tsunekawa Taku; Kano-Hayashi Hatsuyo; Iguchi Akihisa; Sumi Daigo; Ignarro Louis J
A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits.
Atherosclerosis 2004;176(2):255-63.
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2004: Juliet Packiasamy A R; Hayashi Toshio; Daigo Sumi; Matsui-Hirai Hisako; Miyazaki Asaka; Fukatsu Akiko; Funami Jun; Iguchi Akihisa; Ignarro Louis J
Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells.
Biochimica et biophysica acta 2004;1693(3):185-91.
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2004: Sumi Daigo; Ignarro Louis J
Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated raw 264.7 cells: the role of heme oxygenase-1 and endogenous nitric oxide.
Diabetes 2004;53(7):1841-50.
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2004: Napoli C; Sica V; de Nigris F; Pignalosa O; Condorelli M; Ignarro L J; Liguori A
Sulfhydryl angiotensin-converting enzyme inhibition induces sustained reduction of systemic oxidative stress and improves the nitric oxide pathway in patients with essential hypertension.
American heart journal 2004;148(1):e5.
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2004: Ignarro Louis J; Napoli Claudio
Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.
Current atherosclerosis reports 2004;6(4):281-7.
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2004: Ongini Ennio; Impagnatiello Francesco; Bonazzi Albino; Guzzetta Massimiliano; Govoni Mirco; Monopoli Angela; Del Soldato Piero; Ignarro Louis J
Nitric oxide (NO)-releasing statin derivatives, a class of drugs showing enhanced antiproliferative and antiinflammatory properties.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8497-502.
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2004: Napoli Claudio; Williams-Ignarro Sharon; De Nigris Filomena; Lerman Lilach O; Rossi Loredana; Guarino Carmen; Mansueto Gelsomina; Di Tuoro Francesco; Pignalosa Orlando; De Rosa Gaetano; Sica Vincenzo; Ignarro Louis J
Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8797-802.
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2004: Garbán Hermes J; Buga Georgette M; Ignarro Louis J
Estrogen receptor-mediated vascular responsiveness to nebivolol: a novel endothelium-related mechanism of therapeutic vasorelaxation.
Journal of cardiovascular pharmacology 2004;43(5):638-44.
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2004: Takeuchi Kazuhiko; Watanabe Hiroshi; Tran Quang-Kim; Ozeki Mariko; Sumi Daigo; Hayashi Toshio; Iguchi Akihisa; Ignarro Louis J; Ohashi Kyoichi; Hayashi Hideharu
Nitric oxide: inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression.
Cardiovascular research 2004;62(1):194-201.
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2004: Hayashi Toshio; Sumi Daigo; Juliet Packiasamy A R; Matsui-Hirai Hisako; Asai-Tanaka Yukako; Kano Hatsuyo; Fukatsu Akiko; Tsunekawa Taku; Miyazaki Asaka; Iguchi Akihisa; Ignarro Louis J
Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits.
Cardiovascular research 2004;61(2):339-51.
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2003: Castellá Manuel; Buckberg Gerald D; Saleh Saleh; Tan Zhongtuo; Ignarro Louis J
A new role for cardioplegic buffering: should acidosis or calcium accumulation be counteracted to salvage jeopardized hearts?
The Journal of thoracic and cardiovascular surgery 2003;126(5):1442-8.
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2003: Sumi Daigo; Ignarro Louis J
Estrogen-related receptor alpha 1 up-regulates endothelial nitric oxide synthase expression.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14451-6.
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2003: Juliet Packiasamy A R; Hayashi Toshio; Iguchi Akihisa; Ignarro Louis J
Concomitant production of nitric oxide and superoxide in human macrophages.
Biochemical and biophysical research communications 2003;310(2):367-70.
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2003: de Nigris Filomena; Lerman Amir; Ignarro Louis J; Williams-Ignarro Sharon; Sica Vincenzo; Baker Andrew H; Lerman Lilach O; Geng Yong J; Napoli Claudio
Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis.
Trends in molecular medicine 2003;9(8):351-9.
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2003: Jacobs Aaron T; Ignarro Louis J
Cell density-enhanced expression of inducible nitric oxide synthase in murine macrophages mediated by interferon-beta.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;8(4):222-30.
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2003: Sumi Daigo; Hayashi Toshio; Matsui-Hirai Hisako; Jacobs Aaron T; Ignarro Louis J; Iguchi Akihisa
17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells.
Biochimica et biophysica acta 2003;1640(2-3):113-8.
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2003: Cirino Giuseppe; Sorrentino Raffaella; di Villa Bianca Roberta d'Emmanuele; Popolo Ada; Palmieri Alessandro; Imbimbo Ciro; Fusco Ferdinando; Longo Nicola; Tajana Gianfranco; Ignarro Louis J; Mirone Vincenzo
Involvement of beta 3-adrenergic receptor activation via cyclic GMP- but not NO-dependent mechanisms in human corpus cavernosum function.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5531-6.
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2003: Allen Bradley S; Veluz Jeffrey S; Buckberg Gerald D; Aeberhard Ernesto; Ignarro Louis J
Deep hypothermic circulatory arrest and global reperfusion injury: avoidance by making a pump prime reperfusate--a new concept.
The Journal of thoracic and cardiovascular surgery 2003;125(3):625-32.
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2003: Chiang Scott; Azizzadeh Babak; Buga Georgette; Ignarro Lou; Calcaterra Thomas; Blackwell Keith
Local administration of nitric oxide donor significantly impacts microvascular thrombosis.
The Laryngoscope 2003;113(3):406-9.
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2003: Jacobs Aaron T; Ignarro Louis J
Nuclear factor-kappa B and mitogen-activated protein kinases mediate nitric oxide-enhanced transcriptional expression of interferon-beta.
The Journal of biological chemistry 2003;278(10):8018-27.
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2003: Davis Michael R; Ortegon Delio P; Kerby Jeffrey D; Ignarro Louis J; Kashyap Vikram S
Endothelial dysfunction after arterial thrombosis is ameliorated by L-arginine in combination with thrombolysis.
Journal of vascular and interventional radiology : JVIR 2003;14(2 Pt 1):233-9.
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2003: de Nigris Filomena; Lerman Lilach O; Ignarro Sharon Williams; Sica Giacomo; Lerman Amir; Palinski Wulf; Ignarro Louis J; Napoli Claudio
Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1420-5.
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2003: Azizzadeh Babak; Buga Georgette M; Berke Gerald S; Larian Babak; Ignarro Louis J; Blackwell Keith E
Inhibitors of nitric oxide promote microvascular thrombosis.
Archives of facial plastic surgery : official publication for the American Academy of Facial Plastic and Reconstructive Surgery, Inc. and the International Federation of Facial Plastic Surgery Societies 2003;5(1):31-5.
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2003: Napoli Claudio; Ignarro Louis J
Nitric oxide-releasing drugs.
Annual review of pharmacology and toxicology 2003;43():97-123.
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2002: Ignarro L J
Nitric oxide as a unique signaling molecule in the vascular system: a historical overview.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2002;53(4 Pt 1):503-14.
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2002: Castellá Manuel; Buckberg Gerald D; Tan Zhongtuo; Ignarro Louis J
Myocyte and endothelial effects of preconditioning the jeopardized heart by inhibiting Na/H exchange.
The Journal of thoracic and cardiovascular surgery 2002;124(6):1113-21.
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2002: Fiorucci Stefano; Antonelli Elisabetta; Distrutti Eleonora; Del Soldato Piero; Flower Roderick J; Clark Mark J Paul; Morelli Antonio; Perretti Mauro; Ignarro Louis J
NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15770-5.
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2002: Ribas Antoni; Amarnani Saral N; Buga Georgette M; Butterfield Lisa H; Dissette Vivian B; McBride William H; Glaspy John A; Ignarro Louis J; Economou James S
Immunosuppressive effects of interleukin-12 coexpression in melanoma antigen gene-modified dendritic cell vaccines.
Cancer gene therapy 2002;9(11):875-83.
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2002: Napoli Claudio; Lerman Lilach O; de Nigris Filomena; Loscalzo Joseph; Ignarro Louis J
Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells.
Journal of the American College of Cardiology 2002;40(8):1515-22.
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2002: Ignarro Louis J; Sisodia Manisha; Trinh Kim; Bedrood Sahar; Wu Guoyao; Wei Liu Hua; Buga Georgette M
Nebivolol inhibits vascular smooth muscle cell proliferation by mechanisms involving nitric oxide but not cyclic GMP.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2002;7(2):83-90.
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2002: Ignarro Louis J; Byrns Russell E; Trinh Kim; Sisodia Manisha; Buga Georgette M
Nebivolol: a selective beta(1)-adrenergic receptor antagonist that relaxes vascular smooth muscle by nitric oxide- and cyclic GMP-dependent mechanisms.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2002;7(2):75-82.
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2002: Cicinelli Ettore; Ignarro Louis J; Galantino Pietro; Pinto Vincenzo; Barba Bruno; Schonauer Sergio
Effects of tibolone on plasma levels of nitric oxide in postmenopausal women.
Fertility and sterility 2002;78(3):464-8.
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2002: Ignarro Louis J
Wei Lun Visiting Professorial Lecture: Nitric oxide in the regulation of vascular function: an historical overview.
Journal of cardiac surgery 2002;17(4):301-6.
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2002: Ignarro Louis J
After 130 years, the molecular mechanism of action of nitroglycerin is revealed.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7816-7.
-
2002: Wallace John L; Ignarro Louis J; Fiorucci Stefano
Potential cardioprotective actions of no-releasing aspirin.
Nature reviews. Drug discovery 2002;1(5):375-82.
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2002: Napoli Claudio; Aldini Giancarlo; Wallace John L; de Nigris Filomena; Maffei Roberto; Abete Pasquale; Bonaduce Domenico; Condorelli Gianluigi; Rengo Franco; Sica Vincenzo; D'Armiento Francesco P; Mignogna Chiara; de Rosa Gaetano; Condorelli Mario; Lerman Lilach O; Ignarro Louis J
Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1689-94.
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2002: Ignarro Louis J; Napoli Claudio; Loscalzo Joseph
Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview.
Circulation research 2002;90(1):21-8.
-
2001: Jacobs A T; Ignarro L J
Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages.
The Journal of biological chemistry 2001;276(51):47950-7.
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2001: Azizzadeh B; Yip H T; Blackwell K E; Horvath S; Calcaterra T C; Buga G M; Ignarro L J; Wang M B
Nitric oxide improves cisplatin cytotoxicity in head and neck squamous cell carcinoma.
The Laryngoscope 2001;111(11 Pt 1):1896-900.
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2001: Bauer P M; Buga G M; Ignarro L J
Role of p42/p44 mitogen-activated-protein kinase and p21waf1/cip1 in the regulation of vascular smooth muscle cell proliferation by nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12802-7.
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2001: Bauer P M; Buga G M; Fukuto J M; Pegg A E; Ignarro L J
Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme.
The Journal of biological chemistry 2001;276(37):34458-64.
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2001: Kashyap V S; Reil T D; Moore W S; Hoang T X; Gelabert H A; Byrns R E; Ignarro L J; Freischlag J A
Acute arterial thrombosis causes endothelial dysfunction: a new paradigm for thrombolytic therapy.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2001;34(2):323-9.
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2001: Wei L H; Wu G; Morris S M; Ignarro L J
Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(16):9260-4.
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2001: Ma L; Elliott S N; Cirino G; Buret A; Ignarro L J; Wallace J L
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6470-5.
-
2001: Napoli C; Ignarro L J
Nitric oxide and atherosclerosis.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2001;5(2):88-97.
-
2001: Ignarro L J; Buga G M; Wei L H; Bauer P M; Wu G; del Soldato P
Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4202-8.
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2001: Napoli C; Cirino G; Del Soldato P; Sorrentino R; Sica V; Condorelli M; Pinto A; Ignarro L J
Effects of nitric oxide-releasing aspirin versus aspirin on restenosis in hypercholesterolemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2860-4.
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2001: Fiorucci S; Mencarelli A; Palazzetti B; Del Soldato P; Morelli A; Ignarro L J
An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2652-7.
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2001: Jayachandran M; Hayashi T; Sumi D; Thakur N K; Kano H; Ignarro L J; Iguchi A
Up-regulation of endothelial nitric oxide synthase through beta(2)-adrenergic receptor--the role of a beta-blocker with NO-releasing action.
Biochemical and biophysical research communications 2001;280(3):589-94.
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2000: Shah S; Hobbs A; Singh R; Cuevas J; Ignarro L J; Chaudhuri G
Gastrointestinal motility during pregnancy: role of nitrergic component of NANC nerves.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1478-85.
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2000: Ignarro L J
The unique role of nitric oxide as a signaling molecule in the cardiovascular system.
Italian heart journal : official journal of the Italian Federation of Cardiology 2000;1 Suppl 3():S28-9.
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2000: Bivalacqua T J; Champion H C; Mehta Y S; Abdel-Mageed A B; Sikka S C; Ignarro L J; Kadowitz P J; Hellstrom W J
Adenoviral gene transfer of endothelial nitric oxide synthase (eNOS) to the penis improves age-related erectile dysfunction in the rat.
International journal of impotence research 2000;12 Suppl 3():S8-17.
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2000: Wei L H; Jacobs A T; Morris S M; Ignarro L J
IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells.
American journal of physiology. Cell physiology 2000;279(1):C248-56.
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2000: Napoli C; Cicala C; Wallace J L; de Nigris F; Santagada V; Caliendo G; Franconi F; Ignarro L J; Cirino G
Protease-activated receptor-2 modulates myocardial ischemia-reperfusion injury in the rat heart.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3678-83.
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2000: Honold J; Pusser N L; Nathan L; Chaudhuri G; Ignarro L J; Sherman M P
Production and excretion of nitrate by human newborn infants: neonates are not little adults.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2000;4(1):35-46.
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2000: Wei L H; Morris S M; Cederbaum S D; Mori M; Ignarro L J
Induction of arginase II in human Caco-2 tumor cells by cyclic AMP.
Archives of biochemistry and biophysics 2000;374(2):255-60.
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1999: Ignarro L J; Cirino G; Casini A; Napoli C
Nitric oxide as a signaling molecule in the vascular system: an overview.
Journal of cardiovascular pharmacology 1999;34(6):879-86.
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1999: Cicinelli E; Ignarro L J; Schonauer L M; Matteo M G; Galantino P; Falco N
Different plasma levels of nitric oxide in arterial and venous blood.
Clinical physiology (Oxford, England) 1999;19(5):440-2.
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1999: Champion H C; Bivalacqua T J; Hyman A L; Ignarro L J; Hellstrom W J; Kadowitz P J
Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11648-52.
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1999: Bauer P M; Fukuto J M; Buga G M; Pegg A E; Ignarro L J
Nitric oxide inhibits ornithine decarboxylase by S-nitrosylation.
Biochemical and biophysical research communications 1999;262(2):355-8.
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1999: Ignarro L J
Nitric oxide: a unique endogenous signaling molecule in vascular biology.
Bioscience reports 1999;19(2):51-71.
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1999: Cicinelli E; Ignarro L J; Matteo M G; Galantino P; Schonauer L M; Falco N
Effects of estrogen replacement therapy on plasma levels of nitric oxide in postmenopausal women.
American journal of obstetrics and gynecology 1999;180(2 Pt 1):334-9.
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1999: Ma S X; Ignarro L J; Byrns R; Li X Y
Increased nitric oxide concentrations in posterior hypothalamus and central sympathetic function on nitrate tolerance following subcutaneous nitroglycerin.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1999;3(2):153-61.
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1998: Gaston B; Fry E; Sears S; Heroman W M; Ignarro L; Stamler J S
Umbilical arterial S-nitrosothiols in stressed newborns: role in perinatal circulatory transition.
Biochemical and biophysical research communications 1998;253(3):899-901.
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1998: Buga G M; Wei L H; Bauer P M; Fukuto J M; Ignarro L J
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
The American journal of physiology 1998;275(4 Pt 2):R1256-64.
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1998: Ding M; Zhang M; Wong J L; Rogers N E; Ignarro L J; Voskuhl R R
Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2560-4.
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1998: Cicinelli E; Ignarro L J; Schönauer L M; Matteo M G; Galantino P; Balzano G
Effects of short-term transdermal estradiol administration on plasma levels of nitric oxide in postmenopausal women.
Fertility and sterility 1998;69(1):58-61.
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1998: Wei L H; Arabolos N; Ignarro L J
Certain S-substituted isothioureas not only inhibit NO synthase catalytic activity but also decrease translation and stability of inducible NO synthase protein.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1998;2(3):155-64.
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1997: Nene S; Gelabert H; Moore W; Quinones-Baldrich W; Santibanez-Gallerani A; Ignarro L
Cigarette smoking increases endothelial-derived vasorelaxation in the rat carotid artery in a dose-dependent manner.
The Journal of surgical research 1997;71(2):101-6.
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1997: Ding M; Wong J L; Rogers N E; Ignarro L J; Voskuhl R R
Gender differences of inducible nitric oxide production in SJL/J mice with experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1997;77(1):99-106.
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1997: Merrill J E; Murphy S P; Mitrovic B; Mackenzie-Graham A; Dopp J C; Ding M; Griscavage J; Ignarro L J; Lowenstein C J
Inducible nitric oxide synthase and nitric oxide production by oligodendrocytes.
Journal of neuroscience research 1997;48(4):372-84.
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1997: Ding M; St Pierre B A; Parkinson J F; Medberry P; Wong J L; Rogers N E; Ignarro L J; Merrill J E
Inducible nitric-oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis.
The Journal of biological chemistry 1997;272(17):11327-35.
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1997: Singh R; Pervin S; Rogers N E; Ignarro L J; Chaudhuri G
Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
Biochemical and biophysical research communications 1997;232(3):672-7.
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1997: Ihnken K; Morita K; Buckberg G D; Winkelmann B; Schmitt M; Ignarro L J; Sherman M P
Nitric-oxide-induced reoxygenation injury in the cyanotic immature heart is prevented by controlling oxygen content during initial reoxygenation.
Angiology 1997;48(3):189-202.
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1997: Mizuno A; Baretti R; Buckberg G D; Young H H; Vinten-Johansen J; Ma X L; Ignarro L J
Endothelial stunning and myocyte recovery after reperfusion of jeopardized muscle: a role of L-arginine blood cardioplegia.
The Journal of thoracic and cardiovascular surgery 1997;113(2):379-89.
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1997: Cicinelli E; Ignarro L J; Lograno M; Matteo G; Falco N; Schonauer L M
Acute effects of transdermal estradiol administration on plasma levels of nitric oxide in postmenopausal women.
Fertility and sterility 1997;67(1):63-6.
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1997: Glasgow R E; Buga G M; Ignarro L J; Chaudhuri G; Heymann M A
Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep.
Reproduction, fertility, and development 1997;9(2):213-6.
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1996: Cicinelli E; Ignarro L J; Lograno M; Galantino P; Balzano G; Schonauer L M
Circulating levels of nitric oxide in fertile women in relation to the menstrual cycle.
Fertility and sterility 1996;66(6):1036-8.
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1996: Buga G M; Singh R; Pervin S; Rogers N E; Schmitz D A; Jenkinson C P; Cederbaum S D; Ignarro L J
Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production.
The American journal of physiology 1996;271(5 Pt 2):H1988-98.
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1996: Atiya A; Cohen G; Ignarro L; Brunicardi F C
Nitric oxide regulates insulin secretion in the isolated perfused human pancreas via a cholinergic mechanism.
Surgery 1996;120(2):322-7.
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1996: Cohen G A; Hobbs A J; Fitch R M; Zinner M J; Chaudhuri G; Ignarro L J
Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo.
The American journal of physiology 1996;271(1 Pt 2):H133-9.
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1996: Lee J; Drinkwater D C; Laks H; Chong A; Blitz A; Chen M A; Ignarro L J; Chang P
Preservation of endothelium-dependent vasodilation with low-potassium University of Wisconsin solution.
The Journal of thoracic and cardiovascular surgery 1996;112(1):103-10.
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1996: Morita K; Ihnken K; Buckberg G D; Ignarro L J
Oxidative insult associated with hyperoxic cardiopulmonary bypass in the infantile heart and lung.
Japanese circulation journal 1996;60(6):355-63.
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1996: Ignarro L J
Physiology and pathophysiology of nitric oxide.
Kidney international. Supplement 1996;55():S2-5.
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1996: Morita K; Ihnken K; Buckberg G D; Sherman M P; Ignarro L J
Pulmonary vasoconstriction due to impaired nitric oxide production after cardiopulmonary bypass.
The Annals of thoracic surgery 1996;61(6):1775-80.
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1996: Griscavage J M; Wilk S; Ignarro L J
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3308-12.
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1996: Sheng H; Ignarro L J
Biochemical and immunohistochemical characterization of nitric oxide synthase in the rat retina.
Pharmacological research : the official journal of the Italian Pharmacological Society 1996;33(1):29-34.
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1996: Hobbs A J; Ignarro L J
Nitric oxide-cyclic GMP signal transduction system.
Methods in enzymology 1996;269():134-48.
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1995: Hayashi T; Fukuto J M; Ignarro L J; Chaudhuri G
Gender differences in atherosclerosis: possible role of nitric oxide.
Journal of cardiovascular pharmacology 1995;26(5):792-802.
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1995: Hunt J; Byrns R E; Ignarro L J; Gaston B
Condensed expirate nitrite as a home marker for acute asthma.
Lancet 1995;346(8984):1235-6.
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1995: Radziszewski W; Chopra M; Zembowicz A; Gryglewski R; Ignarro L J; Chaudhuri G
Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins.
International journal of cardiology 1995;51(3):211-20.
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1995: Griscavage J M; Wilk S; Ignarro L J
Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene.
Biochemical and biophysical research communications 1995;215(2):721-9.
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1995: Ihnken K; Morita K; Buckberg G D; Sherman M P; Ignarro L J; Young H H
Studies of hypoxemic/reoxygenation injury: with aortic clamping. XIII. Interaction between oxygen tension and cardioplegic composition in limiting nitric oxide production and oxidant damage.
The Journal of thoracic and cardiovascular surgery 1995;110(4 Pt 2):1274-86.
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1995: Morita K; Sherman M P; Buckberg G D; Ihnken K; Matheis G; Young H H; Ignarro L J
Studies of hypoxemic/reoxygenation injury: without aortic clamping. V. Role of the L-arginine-nitric oxide pathway: the nitric oxide paradox.
The Journal of thoracic and cardiovascular surgery 1995;110(4 Pt 2):1200-11.
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1995: Abu-Soud H M; Wang J; Rousseau D L; Fukuto J M; Ignarro L J; Stuehr D J
Neuronal nitric oxide synthase self-inactivates by forming a ferrous-nitrosyl complex during aerobic catalysis.
The Journal of biological chemistry 1995;270(39):22997-3006.
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1995: Wang W W; Jenkinson C P; Griscavage J M; Kern R M; Arabolos N S; Byrns R E; Cederbaum S D; Ignarro L J
Co-induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide.
Biochemical and biophysical research communications 1995;210(3):1009-16.
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1995: Patel A G; Toyama M T; Nguyen T N; Cohen G A; Ignarro L J; Reber H A; Ashley S W
Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats.
Gastroenterology 1995;108(4):1215-20.
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1995: Mitrovic B; Ignarro L J; Vinters H V; Akers M A; Schmid I; Uittenbogaart C; Merrill J E
Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes.
Neuroscience 1995;65(2):531-9.
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1995: Aeberhard E E; Henderson S A; Arabolos N S; Griscavage J M; Castro F E; Barrett C T; Ignarro L J
Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene.
Biochemical and biophysical research communications 1995;208(3):1053-9.
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1995: Hyun J; Komori Y; Chaudhuri G; Ignarro L J; Fukuto J M
The protective effect of tetrahydrobiopterin on the nitric oxide-mediated inhibition of purified nitric oxide synthase.
Biochemical and biophysical research communications 1995;206(1):380-6.
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1995: Griscavage J M; Hobbs A J; Ignarro L J
Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds.
Advances in pharmacology (San Diego, Calif.) 1995;34():215-34.
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1995: Ihnken K; Morita K; Buckberg G D; Ignarro L J; Beyersdorf F
Reduction of reoxygenation injury and nitric oxide production in the cyanotic immature heart by controlling pO2.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1995;9(8):410-8.
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1994: Chang G J; Woo P; Honda H M; Ignarro L J; Young L; Berliner J A; Demer L L
Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide. Dependence on pH and oxygen.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(11):1808-14.
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1994: Hobbs A J; Fukuto J M; Ignarro L J
Formation of free nitric oxide from l-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10992-6.
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1994: Henderson S A; Lee P H; Aeberhard E E; Adams J W; Ignarro L J; Murphy W J; Sherman M P
Nitric oxide reduces early growth response-1 gene expression in rat lung macrophages treated with interferon-gamma and lipopolysaccharide.
The Journal of biological chemistry 1994;269(41):25239-42.
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1994: Mitrovic B; Ignarro L J; Montestruque S; Smoll A; Merrill J E
Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro.
Neuroscience 1994;61(3):575-85.
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1994: Griscavage J M; Fukuto J M; Komori Y; Ignarro L J
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
The Journal of biological chemistry 1994;269(34):21644-9.
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1994: Slusher B S; Zacco A E; Maslanski J A; Norris T E; McLane M W; Moore W C; Rogers N E; Ignarro L J
The cloned neurotensin receptor mediates cyclic GMP formation when coexpressed with nitric oxide synthase cDNA.
Molecular pharmacology 1994;46(1):115-21.
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1994: Morita K; Ihnken K; Buckberg G D; Sherman M P; Young H H; Ignarro L J
Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.
The Journal of clinical investigation 1994;93(6):2658-66.
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1994: Pearl J M; Laks H; Drinkwater D C; Sorensen T J; Chang P; Aharon A S; Byrns R E; Ignarro L J
Loss of endothelium-dependent vasodilatation and nitric oxide release after myocardial protection with University of Wisconsin solution.
The Journal of thoracic and cardiovascular surgery 1994;107(1):257-64.
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1994: Ignarro L J
Regulation of cytosolic guanylyl cyclase by porphyrins and metalloporphyrins.
Advances in pharmacology (San Diego, Calif.) 1994;26():35-65.
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1994: Mitrovic B; Martin F C; Charles A C; Ignarro L J; Anton P A; Shanahan F; Merrill J E
Neurotransmitters and cytokines in CNS pathology.
Progress in brain research 1994;103():319-30.
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1993: Chaudhuri G; Cuevas J; Buga G M; Ignarro L J
NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels.
The American journal of physiology 1993;265(6 Pt 2):H2036-43.
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1993: Griscavage J M; Rogers N E; Sherman M P; Ignarro L J
Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6329-37.
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1993: Moriel E Z; Gonzalez-Cadavid N; Ignarro L J; Byrns R; Rajfer J
Levels of nitric oxide metabolites do not increase during penile erection.
Urology 1993;42(5):551-3.
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1993: Buga G M; Griscavage J M; Rogers N E; Ignarro L J
Negative feedback regulation of endothelial cell function by nitric oxide.
Circulation research 1993;73(5):808-12.
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1993: Fukuto J M; Hobbs A J; Ignarro L J
Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems: the role of physiological oxidants and relevance to the biological activity of HNO.
Biochemical and biophysical research communications 1993;196(2):707-13.
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1993: Ignarro L J; Fukuto J M; Griscavage J M; Rogers N E; Byrns R E
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8103-7.
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1993: Gilliam M B; Sherman M P; Griscavage J M; Ignarro L J
A spectrophotometric assay for nitrate using NADPH oxidation by Aspergillus nitrate reductase.
Analytical biochemistry 1993;212(2):359-65.
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1993: Merrill J E; Ignarro L J; Sherman M P; Melinek J; Lane T E
Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2132-41.
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1993: Ignarro L J
Nitric oxide-mediated vasorelaxation.
Thrombosis and haemostasis 1993;70(1):148-51.
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1993: McNamara D B; Bedi B; Aurora H; Tena L; Ignarro L J; Kadowitz P J; Akers D L
L-arginine inhibits balloon catheter-induced intimal hyperplasia.
Biochemical and biophysical research communications 1993;193(1):291-6.
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1993: McMahon T J; Ignarro L J; Kadowitz P J
Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(4):1704-11.
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1993: Sherman M P; Aeberhard E E; Wong V Z; Griscavage J M; Ignarro L J
Pyrrolidine dithiocarbamate inhibits induction of nitric oxide synthase activity in rat alveolar macrophages.
Biochemical and biophysical research communications 1993;191(3):1301-8.
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1993: Trigo-Rocha F; Aronson W J; Hohenfellner M; Ignarro L J; Rajfer J; Lue T F
Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs.
The American journal of physiology 1993;264(2 Pt 2):H419-22.
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1993: Day R W; Klitzner T S; Ignarro L J
Endothelium-dependent relaxation and the acute pulmonary vascular response to alveolar hyperoxia in neonatal pigs.
Biology of the neonate 1993;63(6):389-96.
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1992: Varela A F; Runge A; Ignarro L J; Chaudhuri G
Nitric oxide and prostacyclin inhibit fetal platelet aggregation: a response similar to that observed in adults.
American journal of obstetrics and gynecology 1992;167(6):1599-604.
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1992: Hayashi T; Fukuto J M; Ignarro L J; Chaudhuri G
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11259-63.
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1992: Rogers N E; Ignarro L J
Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine.
Biochemical and biophysical research communications 1992;189(1):242-9.
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1992: Sherman M P; Griscavage J M; Ignarro L J
Nitric oxide-mediated neuronal injury in multiple sclerosis.
Medical hypotheses 1992;39(2):143-6.
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1992: Bush P A; Gonzalez N E; Ignarro L J
Biosynthesis of nitric oxide and citrulline from L-arginine by constitutive nitric oxide synthase present in rabbit corpus cavernosum.
Biochemical and biophysical research communications 1992;186(1):308-14.
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1992: Bush P A; Gonzalez N E; Griscavage J M; Ignarro L J
Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine.
Biochemical and biophysical research communications 1992;185(3):960-6.
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1992: Bush P A; Aronson W J; Buga G M; Rajfer J; Ignarro L J
Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum.
The Journal of urology 1992;147(6):1650-5.
-
1992: Ignarro L J
Haem-dependent activation of cytosolic guanylate cyclase by nitric oxide: a widespread signal transduction mechanism.
Biochemical Society transactions 1992;20(2):465-9.
-
1992: Buga G M; Ignarro L J
Electrical field stimulation causes endothelium-dependent and nitric oxide-mediated relaxation of pulmonary artery.
The American journal of physiology 1992;262(4 Pt 2):H973-9.
-
1992: Matheis G; Sherman M P; Buckberg G D; Haybron D M; Young H H; Ignarro L J
Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury.
The American journal of physiology 1992;262(2 Pt 2):H616-20.
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1992: Rajfer J; Aronson W J; Bush P A; Dorey F J; Ignarro L J
Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission.
The New England journal of medicine 1992;326(2):90-4.
-
1992: Ignarro L J
Mechanism of action of nitric oxide: heme-dependent activation of guanylate cyclase represents a unifying signal transduction mechanism.
Japanese journal of pharmacology 1992;58 Suppl 2():207P-212P.
-
1992: Day R W; Lai W W; Klitzner T S; Ignarro L J
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
Developmental pharmacology and therapeutics 1992;19(2-3):90-8.
-
1991: Vargas H M; Cuevas J M; Ignarro L J; Chaudhuri G
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.
The Journal of pharmacology and experimental therapeutics 1991;257(3):1208-15.
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1991: Ross G; Chaudhuri G; Ignarro L J; Chyu K Y
Acetylcholine vasodilation of resistance vessels in vivo may not entirely depend on newly synthesized nitric oxide.
European journal of pharmacology 1991;195(2):291-3.
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1991: Chaudhuri G; Heymann M A; Ignarro L J; Longo L D; McNellis D; Mitchell M D; Vanhoutte P M
Research recommendations and conclusions from the National Institutes of Child Health and Human Development Conference on Endothelium-Derived Vasoactive Substances in Perinatal Research.
Seminars in perinatology 1991;15(1):2-3.
-
1991: Buga G M; Gold M E; Fukuto J M; Ignarro L J
Shear stress-induced release of nitric oxide from endothelial cells grown on beads.
Hypertension 1991;17(2):187-93.
-
1991: Chaudhuri G; Buga G M; Gold M E; Wood K S; Ignarro L J
Characterization and actions of human umbilical endothelium derived relaxing factor.
British journal of pharmacology 1991;102(2):331-6.
-
1991: Ignarro L J
Signal transduction mechanisms involving nitric oxide.
Biochemical pharmacology 1991;41(4):485-90.
-
1991: Ignarro L J
Physiological significance of endogenous nitric oxide.
Seminars in perinatology 1991;15(1):20-6.
-
1991: Ignarro L J; Ross G; Tillisch J
Pharmacology of endothelium-derived nitric oxide and nitrovasodilators.
The Western journal of medicine 1991;154(1):51-62.
-
1991: Ignarro L J
Heme-dependent activation of guanylate cyclase by nitric oxide: a novel signal transduction mechanism.
Blood vessels 1991;28(1-3):67-73.
-
1990: Gold M E; Wood K S; Byrns R E; Buga G M; Ignarro L J
L-arginine-dependent vascular smooth muscle relaxation and cGMP formation.
The American journal of physiology 1990;259(6 Pt 2):H1813-21.
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1990: Vargas H M; Ignarro L J; Chaudhuri G
Physiological release of nitric oxide is dependent on the level of vascular tone.
European journal of pharmacology 1990;190(3):393-7.
-
1990: Ignarro L J
Nitric oxide. A novel signal transduction mechanism for transcellular communication.
Hypertension 1990;16(5):477-83.
-
1990: Ignarro L J; Bush P A; Buga G M; Rajfer J
Neurotransmitter identity doubt.
Nature 1990;347(6289):131-2.
-
1990: Pearce W J; Reynier-Rebuffel A M; Lee J; Aubineau P; Ignarro L; Seylaz J
Effects of methylene blue on hypoxic cerebral vasodilatation in the rabbit.
The Journal of pharmacology and experimental therapeutics 1990;254(2):616-25.
-
1990: Ignarro L J; Bush P A; Buga G M; Wood K S; Fukuto J M; Rajfer J
Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.
Biochemical and biophysical research communications 1990;170(2):843-50.
-
1990: Wood K S; Buga G M; Byrns R E; Ignarro L J
Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide.
Biochemical and biophysical research communications 1990;170(1):80-8.
-
1990: Ignarro L J
Haem-dependent activation of guanylate cyclase and cyclic GMP formation by endogenous nitric oxide: a unique transduction mechanism for transcellular signaling.
Pharmacology & toxicology 1990;67(1):1-7.
-
1990: Gold M E; Wood K S; Byrns R E; Fukuto J; Ignarro L J
NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4430-4.
-
1990: Fukuto J M; Wood K S; Byrns R E; Ignarro L J
NG-amino-L-arginine: a new potent antagonist of L-arginine-mediated endothelium-dependent relaxation.
Biochemical and biophysical research communications 1990;168(2):458-65.
-
1990: Gold M E; Buga G M; Wood K S; Byrns R E; Chaudhuri G; Ignarro L J
Antagonistic modulatory roles of magnesium and calcium on release of endothelium-derived relaxing factor and smooth muscle tone.
Circulation research 1990;66(2):355-66.
-
1990: Ignarro L J
Biosynthesis and metabolism of endothelium-derived nitric oxide.
Annual review of pharmacology and toxicology 1990;30():535-60.
-
1989: Gold M E; Bush P A; Ignarro L J
Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation.
Biochemical and biophysical research communications 1989;164(2):714-21.
-
1989: Ignarro L J
Endothelium-derived nitric oxide: pharmacology and relationship to the actions of organic nitrate esters.
Pharmaceutical research 1989;6(8):651-9.
-
1989: Ignarro L J
Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein.
Circulation research 1989;65(1):1-21.
-
1989: Gold M E; Wood K S; Buga G M; Byrns R E; Ignarro L J
L-arginine causes whereas L-argininosuccinic acid inhibits endothelium-dependent vascular smooth muscle relaxation.
Biochemical and biophysical research communications 1989;161(2):536-43.
-
1989: Buga G M; Gold M E; Wood K S; Chaudhuri G; Ignarro L J
Endothelium-derived nitric oxide relaxes nonvascular smooth muscle.
European journal of pharmacology 1989;161(1):61-72.
-
1989: Ignarro L J; Gold M E; Buga G M; Byrns R E; Wood K S; Chaudhuri G; Frank G
Basic polyamino acids rich in arginine, lysine, or ornithine cause both enhancement of and refractoriness to formation of endothelium-derived nitric oxide in pulmonary artery and vein.
Circulation research 1989;64(2):315-29.
-
1989: Ignarro L J
Endothelium-derived nitric oxide: actions and properties.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(1):31-6.
-
1989: Ignarro L J
Heme-dependent activation of soluble guanylate cyclase by nitric oxide: regulation of enzyme activity by porphyrins and metalloporphyrins.
Seminars in hematology 1989;26(1):63-76.
-
1988: Ignarro L J; Buga G M; Byrns R E; Wood K S; Chaudhuri G
Endothelium-derived relaxing factor and nitric oxide possess identical pharmacologic properties as relaxants of bovine arterial and venous smooth muscle.
The Journal of pharmacology and experimental therapeutics 1988;246(1):218-26.
-
1988: Ignarro L J; Buga G M; Chaudhuri G
EDRF generation and release from perfused bovine pulmonary artery and vein.
European journal of pharmacology 1988;149(1-2):79-88.
-
1988: Ignarro L J; Byrns R E; Buga G M; Wood K S; Chaudhuri G
Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation.
The Journal of pharmacology and experimental therapeutics 1988;244(1):181-9.
-
1988: Ashwal S; Pearce W J; Ignarro L J
Hypoxia increases cGMP and decreases calcium uptake in rabbit cranial arteries.
Proceedings of the Western Pharmacology Society 1988;31():125-8.
-
1987: Ignarro L J
Contributions to a quest.
Nature 1987;330(6148):526.
-
1987: Ignarro L J; Byrns R E; Buga G M; Wood K S
Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.
Circulation research 1987;61(6):866-79.
-
1987: Ignarro L J; Buga G M; Wood K S; Byrns R E; Chaudhuri G
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9265-9.
-
1987: Ignarro L J; Byrns R E; Buga G M; Wood K S
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.
The American journal of physiology 1987;253(5 Pt 2):H1074-82.
-
1987: Ignarro L J; Wood K S
Activation of purified soluble guanylate cyclase by arachidonic acid requires absence of enzyme-bound heme.
Biochimica et biophysica acta 1987;928(2):160-70.
-
1987: Wood K S; Ignarro L J
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase.
The Journal of biological chemistry 1987;262(11):5020-7.
-
1987: Ignarro L J; Byrns R E; Wood K S
Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein.
Circulation research 1987;60(1):82-92.
-
1986: Ignarro L J; Harbison R G; Wood K S; Kadowitz P J
Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid.
The Journal of pharmacology and experimental therapeutics 1986;237(3):893-900.
-
1986: Guinee D G; McNamara D B; Ignarro L J; Hyman A L; Kadowitz P J
Arachidonic acid and acetylcholine induced relaxation of bovine coronary artery: effect of indomethacin and methylene blue.
The Canadian journal of cardiology 1986;2(3):170-5.
-
1986: Ignarro L J; Wood K S; Harbison R G; Kadowitz P J
Atriopeptin II relaxes and elevates cGMP in bovine pulmonary artery but not vein.
Journal of applied physiology (Bethesda, Md. : 1985) 1986;60(4):1128-33.
-
1986: Ignarro L J; Adams J B; Horwitz P M; Wood K S
Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-deficient enzyme forms.
The Journal of biological chemistry 1986;261(11):4997-5002.
-
1986: Ignarro L J; Harbison R G; Wood K S; Kadowitz P J
Dissimilarities between methylene blue and cyanide on relaxation and cyclic GMP formation in endothelium-intact intrapulmonary artery caused by nitrogen oxide-containing vasodilators and acetylcholine.
The Journal of pharmacology and experimental therapeutics 1986;236(1):30-6.
-
1985: Pretus H A; Ignarro L J; Ensley H E; Feigen L P
Inhibition of soybean lipoxygenase by SKF 525-A and metyrapone.
Prostaglandins 1985;30(4):591-8.
-
1985: Ignarro L J; Harbison R G; Wood K S; Wolin M S; McNamara D B; Hyman A L; Kadowitz P J
Differences in responsiveness of intrapulmonary artery and vein to arachidonic acid: mechanism of arterial relaxation involves cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate.
The Journal of pharmacology and experimental therapeutics 1985;233(3):560-9.
-
1985: Lippton H L; Horwitz P M; McNamara D B; Ignarro L J; Landry A Z; Hyman A L; Kadowitz P J
The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma.
Prostaglandins, leukotrienes, and medicine 1985;18(2):193-204.
-
1985: Ignarro L J; Kadowitz P J
The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation.
Annual review of pharmacology and toxicology 1985;25():171-91.
-
1984: Ignarro L J; Ballot B; Wood K S
Regulation of soluble guanylate cyclase activity by porphyrins and metalloporphyrins.
The Journal of biological chemistry 1984;259(10):6201-7.
-
1984: Ignarro L J; Wood K S; Ballot B; Wolin M S
Guanylate cyclase from bovine lung. Evidence that enzyme activation by phenylhydrazine is mediated by iron-phenyl hemoprotein complexes.
The Journal of biological chemistry 1984;259(9):5923-31.
-
1984: Ignarro L J; Burke T M; Wood K S; Wolin M S; Kadowitz P J
Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery.
The Journal of pharmacology and experimental therapeutics 1984;228(3):682-90.
-
1984: Edwards J C; Ignarro L J; Hyman A L; Kadowitz P J
Relaxation of intrapulmonary artery and vein by nitrogen oxide-containing vasodilators and cyclic GMP.
The Journal of pharmacology and experimental therapeutics 1984;228(1):33-42.
-
1984: Ignarro L J; Wood K S; Wolin M S
Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: a unifying concept.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():267-74.
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1983: Mellion B T; Ignarro L J; Myers C B; Ohlstein E H; Ballot B A; Hyman A L; Kadowitz P J
Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation.
Molecular pharmacology 1983;23(3):653-64.
-
1982: Wolin M S; Wood K S; Ignarro L J
Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme.
The Journal of biological chemistry 1982;257(22):13312-20.
-
1982: Ohlstein E H; Wood K S; Ignarro L J
Purification and properties of heme-deficient hepatic soluble guanylate cyclase: effects of heme and other factors on enzyme activation by NO, NO-heme, and protoporphyrin IX.
Archives of biochemistry and biophysics 1982;218(1):187-98.
-
1982: Ignarro L J; Degnan J N; Baricos W H; Kadowitz P J; Wolin M S
Activation of purified guanylate cyclase by nitric oxide requires heme. Comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung.
Biochimica et biophysica acta 1982;718(1):49-59.
-
1982: Ignarro L J; Wood K S; Wolin M S
Activation of purified soluble guanylate cyclase by protoporphyrin IX.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(9):2870-3.
-
1982: Lippton H L; Gruetter C A; Ignarro L J; Meyer R L; Kadowitz P J
Vasodilator actions of several N-nitroso compounds.
Canadian journal of physiology and pharmacology 1982;60(1):68-75.
-
1981: Gruetter C A; Gruetter D Y; Lyon J E; Kadowitz P J; Ignarro L J
Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.
The Journal of pharmacology and experimental therapeutics 1981;219(1):181-6.
-
1981: Edwards J C; Barry B K; Gruetter D Y; Ohlstein E H; Baricos W H; Ignarro L J
Activation of hepatic guanylate cyclase by nitrosyl-heme complexes. Comparison of unpurified and partially purified enzyme.
Biochemical pharmacology 1981;30(18):2531-8.
-
1981: Ignarro L J; Lippton H; Edwards J C; Baricos W H; Hyman A L; Kadowitz P J; Gruetter C A
Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.
The Journal of pharmacology and experimental therapeutics 1981;218(3):739-49.
-
1981: Mellion B T; Ignarro L J; Ohlstein E H; Pontecorvo E G; Hyman A L; Kadowitz P J
Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators.
Blood 1981;57(5):946-55.
-
1981: Ignarro L J; Kadowitz P J; Baricos W H
Evidence that regulation of hepatic guanylate cyclase activity involves interactions between catalytic site -SH groups and both substrate and activator.
Archives of biochemistry and biophysics 1981;208(1):75-86.
-
1981: Ignarro L J; Barry B K; Gruetter D Y; Ohlstein E H; Gruetter C A; Kadowitz P J; Baricos W H
Selective alterations in responsiveness of guanylate cyclase to activation by nitroso compounds during enzyme purification.
Biochimica et biophysica acta 1981;673(4):394-407.
-
1981: Kadowitz P J; Nandiwada P; Gruetter C A; Ignarro L J; Hyman A L
Pulmonary vasodilator responses to nitroprusside and nitroglycerin in the dog.
The Journal of clinical investigation 1981;67(3):893-902.
-
1981: Gruetter C A; Ignarro L J; Hyman A L; Kadowitz P J
Contractile effects of 5-hydroxytryptamine in isolated intrapulmonary arteries and veins.
Canadian journal of physiology and pharmacology 1981;59(2):157-62.
-
1981: Gruetter C A; Kadowitz P J; Ignarro L J
Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite.
Canadian journal of physiology and pharmacology 1981;59(2):150-6.
-
1980: McNamara D B; Kadowitz P J; Hyman A L; Ignarro L J
Adenosine 3',5'-monophosphate formation by preparations of rat liver soluble guanylate cyclase activated with nitric oxide, nitrosyl ferroheme, S-nitrosothiols, and other nitroso compounds.
Canadian journal of physiology and pharmacology 1980;58(12):1446-56.
-
1980: Gruetter D Y; Gruetter C A; Barry B K; Baricos W H; Hyman A L; Kadowitz P J; Ignarro L J
Activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside, and nitrosoguanidine--inhibition by calcium, lanthanum, and other cations, enhancement by thiols.
Biochemical pharmacology 1980;29(21):2943-50.
-
1980: Ignarro L J; Gruetter C A
Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: possible involvement of S-nitrosothiols.
Biochimica et biophysica acta 1980;631(2):221-31.
-
1980: Gruetter C A; Barry B K; McNamara D B; Kadowitz P J; Ignarro L J
Coronary arterial relaxation and guanylate cyclase activation by cigarette smoke, N'-nitrosonornicotine and nitric oxide.
The Journal of pharmacology and experimental therapeutics 1980;214(1):9-15.
-
1980: Ignarro L J; Barry B K; Gruetter D Y; Edwards J C; Ohlstein E H; Gruetter C A; Baricos W H
Guanylate cyclase activation of nitroprusside and nitrosoguanidine is related to formation of S-nitrosothiol intermediates.
Biochemical and biophysical research communications 1980;94(1):93-100.
-
1980: Napoli S A; Gruetter C A; Ignarro L J; Kadowitz P J
Relaxation of bovine coronary arterial smooth muscle by cyclic GMP, cyclic AMP and analogs.
The Journal of pharmacology and experimental therapeutics 1980;212(3):469-73.
-
1980: Ignarro L J; Edwards J C; Gruetter D Y; Barry B K; Gruetter C A
Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds.
FEBS letters 1980;110(2):275-8.
-
1979: Gruetter D Y; Ignarro L J
Arachidonic acid activation of guinea pig lung guanylate cyclase by two independent mechanisms.
Prostaglandins 1979;18(4):541-56.
-
1979: Ohlstein E H; Barry B K; Gruetter D Y; Ignarro L J
Methemoglobin blockade of coronary arterial soluble guanylate cyclase activation by nitroso compounds and its reversal with dithiothreitol.
FEBS letters 1979;102(2):316-20.
-
1979: Gruetter C A; Barry B K; McNamara D B; Gruetter D Y; Kadowitz P J; Ignarro L
Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine.
Journal of cyclic nucleotide research 1979;5(3):211-24.
-
1978: Ignarro L J; Gross R A
Stimulation of mammalian adenylate cyclase activity with guanosine 5'-tetraphosphate and other guanine nucleotides.
Biochimica et biophysica acta 1978;541(2):170-80.
-
1978: Cech S Y; Ignarro L J
Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver.
Biochemical and biophysical research communications 1978;80(1):119-25.
-
1978: Ignarro L J
Interference with stimulus-secretion coupling by glucocorticosteroids.
Advances in cyclic nucleotide research 1978;9():677-89.
-
1977: Cech S Y; Ignarro L J
Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues.
Science (New York, N.Y.) 1977;198(4321):1063-5.
-
1977: Ignarro L J
Glucocorticosteroid inhibition of nonphagocytic discharge of lysosomal enzymes from human neutrophils.
Arthritis and rheumatism 1977;20(1):73-83.
-
1976: Ignarro L J; Gross R A; Gross D M
Inhibition of mammalian soluble guanylate cyclase activity by adenosine 5'-tetraphosphate, guanosine 5'-tetraphosphate and other nucleotides.
Journal of cyclic nucleotide research 1976;2(5):337-46.
-
1976: Ignarro L J; Cech S Y
Bidirectional regulation of lysosomal enzyme secretion and phagocytosis in human neutrophils by guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1976;151(3):448-52.
-
1975: Smith R J; Ignarro L J
Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(1):108-12.
-
1975: George W J; Ignarro L J; Paddock R J; White L; Kadowitz P J
Oppositional effects of acetylcholine and isoproterenol on isometric tension and cyclic nucleotide concentrations in rabbit atria.
Journal of cyclic nucleotide research 1975;1(5):339-47.
-
1975: George W J; Busuttil R W; Paddock R J; White L A; Ignarro L J
Opposing regulatory influences of cyclic guanosine monophosphate and cyclic adenosine monophosphate in the control of cardiac muscle contraction.
Recent advances in studies on cardiac structure and metabolism 1975;8():243-50.
-
1975: Ignarro L J
Regulation of lysosomal enzyme release by prostaglandins, autonomic neurohormones and cyclic nucleotides.
Frontiers of biology 1975;43(4):481-523.
-
1975: George W J; Ignarro L J; White L E
Muscarinic stimulation of cardiac guanylate cyclase.
Recent advances in studies on cardiac structure and metabolism 1975;7():381-90.
-
1975: Ignarro L J; Cech S Y
Lysosomal enzyme secretion from human neutrophils mediated by cyclic CMP: inhibition of cyclic GMP accumulation and neutrophil function by glucocorticosteroids.
Journal of cyclic nucleotide research 1975;1(6):283-92.
-
1974: Smith R J; Ignarro L J; Heidger P M; Fisher J W
Lysosomal enzyme release in vivo: an evaluation of the mechanism of cobalt polycythemia.
The Journal of pharmacology and experimental therapeutics 1974;191(3):564-74.
-
1974: Ignarro L J
Regulation of lysosomal enzyme secretion: role in inflammation.
Agents and actions 1974;4(4):241-58.
-
1974: Smith R J; Ignarro L J; Fisher J W
Lysosomal enzyme release: a possible mechanism of action of cobalt as an erythropoietic stimulant.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1974;146(3):781-5.
-
1974: Ignarro L J
Release of neutral protease and beta-glucuronidase from human neutrophils in the presence of cartilage treated with various immunologic reactants.
Journal of immunology (Baltimore, Md. : 1950) 1974;113(1):298-308.
-
1974: Ignarro L J; George W J
Mediation of immunologic discharge of lysosomal enzymes from human neutrophils by guanosine 3',5'-monophosphate. Requirement of calcium, and inhibition by adenosine 3',5'-monophosphate.
The Journal of experimental medicine 1974;140(1):225-38.
-
1974: Ignarro L J; Lint T F; George W J
Hormonal control of lysosomal enzyme release from human neutrophils. Effects of autonomic agents on enzyme release, phagocytosis, and cylic nucleotide levels.
The Journal of experimental medicine 1974;139(6):1395-414.
-
1974: Ignarro L J; George W J
Hormonal control of lysosomal enzyme release from human neutrophils: elevation of cyclic nucleotide levels by autonomic neurohormones.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(5):2027-31.
-
1974: Ignarro L J; Paddock R J; George W J
Hormonal control of neutrophil lysosomal enzyme release: effect of epinephrine on adenosine 3',5'-monophosphate.
Science (New York, N.Y.) 1974;183(127):855-7.
-
1974: Ignarro L J
Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate.
Journal of immunology (Baltimore, Md. : 1950) 1974;112(1):210-4.
-
1974: Ignarro L J
Nonphagocytic release of neutral protease and beta-glucuronidase from human neutrophils. Regulation by autonomic neurohormones and cyclic nucleotides.
Arthritis and rheumatism 1974;17(1):25-36.
-
1973: Ignarro L J; Oronsky A L; Perper R J
Breakdown of noncollagenous chondromucoprotein matrix by leukocyte lysosome granule lysates from guinea pig, rabbit, and human.
Clinical immunology and immunopathology 1973;2(1):36-51.
-
1973: Ignarro L J
Neutral protease release from human leukocytes regulated by neurohormones and cyclic nucleotides.
Nature: New biology 1973;245(144):151-4.
-
1973: Oronsky A; Ignarro L; Perper R
Release of cartilage mucopolysaccharide-degrading neutral protease from human leukocytes.
The Journal of experimental medicine 1973;138(2):461-72.
-
1973: Ignarro L J; Krassikoff N; Slywka J
Release of enzymes from a rat liver lysosome fraction: inhibition by catecholamines and cyclic3', 5'-adenosine monophosphate, stimulation by cholinergic agents and cyclic 3', 5'-guanosine monophosphate.
The Journal of pharmacology and experimental therapeutics 1973;186(1):86-99.
-
1973: Ignarro L J
Preservation of structural integrity of liver lysosomes and membrane-stabilizing action of anti-inflammatory drugs, catecholamines and cyclic adenosine monophosphate in isotonic salt media.
Biochemical pharmacology 1973;22(11):1269-82.
-
1973: Ignarro L J; Colombo C
Enzyme release from polymorphonuclear leukocyte lysosomes: regulation by autonomic drugs and cyclic nucleotides.
Science (New York, N.Y.) 1973;180(91):1181-3.
-
1972: Ignarro L J; Colombo C
Enzyme release from guinea-pig polymorphonuclear leucocyte lysosomes inhibited in vitro by anti-inflammatory drugs.
Nature: New biology 1972;239(92):155-7.
-
1972: Ignarro L J
Lysosome membrane stabilization in vivo: effects of steroidal and nonsteroidal anti-inflammatory drugs on the integrity of rat liver lysosomes.
The Journal of pharmacology and experimental therapeutics 1972;182(1):179-88.
-
1972: Ignarro L J; Krassikoff N; Slywka J
Inhibition of lysosomal enzyme release by adenosine 5' triphosphate and N 6 ,O 2 -dibutyryl cyclic 3',5'-adenosine monophosphate.
Life sciences. Pt. 1: Physiology and pharmacology 1972;11(7):317-22.
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1972: Ignarro L J; Slywka J
Changes in liver lysosome fragility, erythrocyte membrane stability, and local and systemic lysosomal enzyme levels in adjuvant-induced polyarthritis.
Biochemical pharmacology 1972;21(6):875-86.
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1971: Ignarro L J; Slywka J; Krassikoff N
Inhibition of lysosomal enzyme release by catecholamines: possible mediation by cyclic 3',5'-adenosine monophosphate.
Life sciences. Pt. 1: Physiology and pharmacology 1971;10(22):1309-15.
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1971: Ignarro L J
Dissimilar effects of anti-inflammatory drugs on stability of lysosomes from peritoneal and circulating leukocytes and liver.
Biochemical pharmacology 1971;20(10):2861-70.
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1971: Ignarro L J
Effects of anti-inflammatory drugs on the stability of rat liver lysosomes in vitro.
Biochemical pharmacology 1971;20(10):2847-60.
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1968: Ignarro L J; Titus E
The presence of antagonistically acting alpha and beta adrenergic receptors in the mouse spleen.
The Journal of pharmacology and experimental therapeutics 1968;160(1):72-80.
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1968: Ignarro L J; Shideman F E
Norepinephrine and epinephrine in the embryo and embryonic heart of the chick: uptake and subcellular distribution.
The Journal of pharmacology and experimental therapeutics 1968;159(1):49-58.
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1968: Ignarro L J; Shideman F E
The requriement of sympathetic innervation for the active transport of norepinephrine by the heart.
The Journal of pharmacology and experimental therapeutics 1968;159(1):59-65.
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1968: Ignarro L J; Shideman F E
Appearance and concentrations of catecholamines and their biosynthesis in the embryonic and developing chick.
The Journal of pharmacology and experimental therapeutics 1968;159(1):38-48.
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1968: Ignarro L J; Shideman F E
Catechol-O-methyl transferase and monoamine oxidase activities in the heart and liver of the embryonic and developing chick.
The Journal of pharmacology and experimental therapeutics 1968;159(1):29-37.
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1967: Shideman F E; Ignarro L J
New species may create new problems: norepinephrine in the heart of the avian embryo.
Federation proceedings 1967;26(4):1137-8.
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