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Hironobu Ihn

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Yuka Oshikawa; Satoshi Fukushima; Noritoshi Honda; Kuniko Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Hironobu Ihn
Decreased miR-7 Expression in the Skin and Sera of Patients with Dermatomyositis.
Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Shinichi Masuguchi; Keisuke Sakai; Satoshi Fukushima; Noritoshi Honda; Yuji Inoue; Masatoshi Jinnin; Hironobu Ihn
Scleroderma dermal fibroblasts overexpress vascular endothelial growth factor due to autocrine transforming growth factor β signaling.
Katsunari Makino; Takamitsu Makino; Shinichi Masuguchi; Keisuke Sakai; Keitaro Yamane; Mitsuhiko Eto; Satoshi Fukushima; Ayaka Hirano; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Takamitsu Kusano; Hironobu Ihn
The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma.

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2013: Yuka Oshikawa; Satoshi Fukushima; Noritoshi Honda; Kuniko Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Hironobu Ihn
Decreased miR-7 Expression in the Skin and Sera of Patients with Dermatomyositis.
Acta dermato-venereologica 2013;93(3):273-6.
2013: Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Shinichi Masuguchi; Keisuke Sakai; Satoshi Fukushima; Noritoshi Honda; Yuji Inoue; Masatoshi Jinnin; Hironobu Ihn
Scleroderma dermal fibroblasts overexpress vascular endothelial growth factor due to autocrine transforming growth factor β signaling.
Modern rheumatology / the Japan Rheumatism Association 2013;23(3):516-24.
2013: Katsunari Makino; Takamitsu Makino; Shinichi Masuguchi; Keisuke Sakai; Keitaro Yamane; Mitsuhiko Eto; Satoshi Fukushima; Ayaka Hirano; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Takamitsu Kusano; Hironobu Ihn
The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(8):3905-15.
2013: Kuniko Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Keitaro Yamane; Satoshi Fukushima; Norithosi Honda; Hironobu Ihn
Down-regulation of miR-223 contributes to the formation of Gottron's papules in dermatomyositis via the induction of PKCɛ.
European journal of dermatology : EJD 2013;23(2):160-7.
2013: Jun Aoi; Satoshi Fukushima; Takashi Hashimoto; Y Inoue; Masatoshi Jinnin; Hiroshi Koga; Katsunari Makino; Shinichi Masuguchi; Keisuke Sakai; Hironobu Ihn
Case of paraneoplastic pemphigus with follicular lymphoma treated with rituximab.
The Journal of dermatology 2013;40(4):285-6.
2013: Minoru Matsuda; Gen Sobue; Kayoko Tahara; Naoki Yamakawa; Hiroaki Adachi; Tatsuya Hoshino; Hironobu Ihn; Daisuke Maji; Tohru Mizushima
Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice.
The Journal of investigative dermatology 2013;133(4):919-28.
2013: H Kanemura; T Makino; S Masuguchi; K Sakai; J Yamashita; J Aoi; S Fukushima; Y Inoue; Masatoshi Jinnin; Hironobu Ihn
Serum epidermal growth factor receptor levels in patients with malignant melanoma.
Clinical and experimental dermatology 2013;38(2):172-7.
2013: Ikko Kajihara; Masato Kidou; Junko Higo; Asako Ichihara; Hironobu Ihn
Pyodermatitis vegetans associated with multiple myeloma.
The Journal of dermatology 2013;40(3):222-3.
2013: Junji Yamashita; Jun Aoi; Satoshi Fukushima; Takeshi Hamasaki; Yuji Inoue; Takuma Iwakiri; Masatoshi Jinnin; Takamitsu Makino; Shinichi Masuguchi; Azusa Miyashita; Hironobu Ihn
The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma.
Melanoma research 2013;23(1):13-20.
2013: Noritoshi Honda; Manabu Fujimoto; Satoshi Fukushima; Minoru Hasegawa; Yuji Inoue; Masatoshi Jinnin; Ikko Kajihara; Tomomi Kira-Etoh; Katsunari Makino; Takamitsu Makino; Yoshinobu Okamoto; Hironobu Ihn
miR-150 down-regulation contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3.
The American journal of pathology 2013;182(1):206-16.
2013: Hideo Kudo; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Keitaro Yamane; Satoshi Fukushima; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Hironobu Ihn
Intravenous immunoglobulin treatment recovers the down-regulated levels of Th1 cytokines in the sera and skin of scleroderma patients.
Journal of dermatological science 2013;69(1):77-80.
2013: A Sakoguchi; S Fukushima; N Honda; K Inoue; Masatoshi Jinnin; I Kajihara; K Makino; T Makino; W Nakayama; Hironobu Ihn
The miR-146a rs2910164 C/G polymorphism is associated with telangiectasia in systemic sclerosis.
Clinical and experimental dermatology 2013;38(1):99-100.
2013: Mitsuhiko Etoh; Satoshi Fukushima; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Keitaro Yamane; Jun Aoi; Hironobu Ihn
microRNA-7 down-regulation mediates excessive collagen expression in localized scleroderma.
Archives of dermatological research 2013;305(1):9-15.
2013: Katsunari Makino; Takamitsu Makino; Keisuke Sakai; Yuji Inoue; Masatoshi Jinnin; Ikko Kajihara; Jun Aoi; Satoshi Fukushima; Ayaka Hirano; Hironobu Ihn
Discoidin domain receptor 2-microRNA 196a-mediated negative feedback against excess type I collagen expression is impaired in scleroderma dermal fibroblasts.
The Journal of investigative dermatology 2013;133(1):110-9.
2013: Keitaro Yamane; Jun Aoi; Tomomi Etoh; Satoshi Fukushima; Yuji Inoue; Tsuyoshi Ishihara; Masatoshi Jinnin; Yuki Kobayashi; Keishi Maruo; Shinichi Masuguchi; Yuichi Oike; Naoki Shimozono; Hironobu Ihn
Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK.
Journal of molecular medicine (Berlin, Germany) 2013;91(1):69-81.
2012: Daisuke Niimori; Kanako Niimori-Kita; Athary Felemban; Hironobu Ihn; Rie Kawano; Hideaki Tanaka; Kunimasa Ohta
Tsukushi controls the hair cycle by regulating TGF-β1 signaling.
Developmental biology 2012;372(1):81-7.
2012: Jun Aoi; Satoshi Fukushima; Y Inoue; Masatoshi Jinnin; Takamitsu Makino; Shinichi Masuguchi; Aki Ogata; Keisuke Sakai; Hironobu Ihn
Case of blastic plasmacytoid dendritic cell neoplasm.
The Journal of dermatology 2012;39(12):1066-7.
2012: Seiji Takashio; Megumi Yamamuro; Hironobu Ihn; Yasuhiro Izumiya; Masatoshi Jinnin; Sunao Kojima; Hisao Ogawa
Diagnostic and prognostic value of subcutaneous tissue biopsy in patients with cardiac amyloidosis.
The American journal of cardiology 2012;110(10):1507-11.
2012: Junji Yamashita; Satoshi Fukushima; Noritoshi Honda; Y Inoue; Masatoshi Jinnin; Katunari Makino; Shinichi Masuguchi; Keisuke Sakai; Hironobu Ihn
Kinesin family member 20A is a novel melanoma-associated antigen.
Acta dermato-venereologica 2012;92(6):593-7.
2012: Aki Kuwahara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Satoshi Fukushima; Noritoshi Honda; Kuniko Inoue; Masatoshi Jinnin; Ikko Kajihara; Hironobu Ihn
Angiogenin expression in the sera and skin of patients with rheumatic diseases.
Bioscience trends 2012;6(5):229-33.
2012: Takaomi Sing; Keitaro Yamane; Satoshi Fukushima; Norihito Honda; Masatoshi Jinnin; Ikko Kajihara; Kastunari Makino; Takamitsu Makino; Shinichi Masuguchi; Keisuke Sakai; Hironobu Ihn
microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma.
Rheumatology (Oxford, England) 2012;51(9):1550-6.
2012: Yasuyo Hayashi; Noritoshi Honda; Satoshi Fukushima; Kuniko Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Wakana Nakayama; Hironobu Ihn
Serum angiopoietin-like protein 3 concentrations in rheumatic diseases.
European journal of dermatology : EJD 2012;22(4):500-4.
2012: Wakana Nakayama; Keisuke Sakai; Satoshi Fukushima; Yuji Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Hironobu Ihn
CD163 expression is increased in the involved skin and sera of patients with systemic lupus erythematosus.
European journal of dermatology : EJD 2012;22(4):512-7.
2012: I Kajihara; T Makino; K Maruo; S Masuguchi; K Sakai; S Fukushima; Y Inoue; Masatoshi Jinnin; Hironobu Ihn
Overexpression of hepatocyte growth factor receptor in scleroderma dermal fibroblasts is caused by autocrine transforming growth factor β signaling.
Bioscience trends 2012;6(3):136-42.
2012: Yuka Oshikawa; Satoshi Fukushima; Masatoshi Jinnin; Takeshi Kawaguchi; Taiga Miyake; Kenta Motomura; Kenichi Nakamura; Yasuhiro Nakashima; Hironobu Ihn
Photosensitivity and acute liver insufficiency in late-onset erythropoietic protoporphyria with a chromosome 18q abnormality.
Case reports in dermatology 2012;4(2):144-9.
2012: Taiji Nakashima; Yoshinobu Okamoto; Keitaro Yamane; Manabu Fujimoto; Satoshi Fukushima; Minoru Hasegawa; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Takamitsu Makino; Shinichi Masuguchi; Hironobu Ihn
Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(8):3573-83.
2012: Noritoshi Honda; Manabu Fujimoto; Satoshi Fukushima; Minoru Hasegawa; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Shinichi Masuguchi; Yoshinobu Okamoto; Hironobu Ihn
TGF-β-mediated downregulation of microRNA-196a contributes to the constitutive upregulated type I collagen expression in scleroderma dermal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):3323-31.
2012: H Kudo; S Masuguchi; K Sakai; S Fukushima; Masatoshi Jinnin; Hironobu Ihn
Cutaneous type adult T-cell leukaemia/lymphoma successfully treated with narrowband ultraviolet B phototherapy.
Clinical and experimental dermatology 2012;37(2):183-4.
2012: Aki Ogata; Otowa Takahashi; Zhe Tian; Jun Aoi; Motoyoshi Endo; Satoshi Fukushima; Hironobu Ihn; Masatoshi Jinnin; Tsuyoshi Kadomatsu; Keishi Miyata; Yuichi Oike
The role of angiopoietin-like protein 2 in pathogenesis of dermatomyositis.
Biochemical and biophysical research communications 2012;418(3):494-9.
2012: Ikko Kajihara; Takamitsu Makino; Shinichi Masuguchi; Yoshinobu Okamoto; Keitaro Yamane; Manabu Fujimoto; Satoshi Fukushima; Minoru Hasegawa; Noritoshi Honda; Tomohide Igata; Masatoshi Jinnin; Hironobu Ihn
Increased accumulation of extracellular thrombospondin-2 due to low degradation activity stimulates type I collagen expression in scleroderma fibroblasts.
The American journal of pathology 2012;180(2):703-14.
2012: Wakana Nakayama; Satoshi Fukushima; Yuji Inoue; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Hironobu Ihn
Serum levels of soluble CD163 in patients with systemic sclerosis.
Rheumatology international 2012;32(2):403-7.
2012: Manabu Tomita; Norihito Yazawa; Makoto Sugaya; Kunihiko Tamaki; Zenshiro Tamaki; Yoshihide Asano; Ryuichi Ashida; Hironobu Ihn; Takafumi Kadono; Tomohiko Kawashima; Masahide Kubo; Hanako Ohmatsu; Shinichi Sato
Serum levels of soluble CD21 in patients with systemic sclerosis.
Rheumatology international 2012;32(2):317-21.
2012: Asako Ichihara; Akihiko Fujisawa; Satoshi Fukushima; Masatoshi Jinnin; Keishi Maruo; Shinichi Masuguchi; Rie Oyama; Keisuke Sakai; Keitaro Yamane; Hironobu Ihn
Increased serum levels of miR-1266 in patients with psoriasis vulgaris.
European journal of dermatology : EJD 2012;22(1):68-71.
2011: A Ichihara; A Fujisawa; Satoshi Fukushima; Masatoshi Jinnin; Keishi Maruo; S Masuguchi; K Sakai; K Yamane; Hironobu Ihn
microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris.
The British journal of dermatology 2011;165(5):1003-10.
2011: Hiroki Arakawa; Satoshi Fukushima; Noritoshi Honda; Masatoshi Jinnin; Ikko Kajihara; Katsunari Makino; Takamitsu Makino; Faith C Muchemwa; Keisuke Sakai; Hironobu Ihn
Adiponectin expression is decreased in the involved skin and sera of diffuse cutaneous scleroderma patients.
Experimental dermatology 2011;20(9):764-6.
2011: S Masuguchi; K Sakai; S Fukushima; Tomohide Igata; Y Inoue; Masatoshi Jinnin; T Makino; Hironobu Ihn
The expression of HER-2 in extramammary Paget's disease.
Bioscience trends 2011;5(4):151-5.
2011: Nobuyo Higashi-Kuwata; Yuji Inoue; Takamitsu Makino; Hironobu Ihn
Expression pattern of VEGFR-1, -2, -3 and D2-40 protein in the skin of patients with systemic sclerosis.
European journal of dermatology : EJD 2011;21(4):490-4.
2011: Hironobu Ihn
[Eosinophilic fasciitis].
Arerugī = [Allergy] 2011;60(6):683-6.
2011: Koji Makino; Satoshi Fukushima; Keishi Maruo; Kiyofumi Egawa; Katsutaro Nishimoto; Hironobu Ihn
Cutaneous hyalohyphomycosis by Scedosporium apiospermum in an immunocompromised patient.
Mycoses 2011;54(3):259-61.
2011: Rie Oyama; Masatoshi Jinnin; Asako Kakimoto; Hisashi Kanemaru; Asako Ichihara; Akihiko Fujisawa; Noritoshi Honda; Shinich Masuguchi; Satoshi Fukushima; Keishi Maruo; Hironobu Ihn
Circulating microRNA associated with TNF-α signaling pathway in patients with plaque psoriasis.
Journal of dermatological science 2011;61(3):209-11.
2011: Hisashi Kanemaru; Satoshi Fukushima; Junji Yamashita; Noritoshi Honda; Rie Oyama; Asako Kakimoto; Shinichi Masuguchi; Tsuyoshi Ishihara; Yuji Inoue; Masatoshi Jinnin; Hironobu Ihn
The circulating microRNA-221 level in patients with malignant melanoma as a new tumor marker.
Journal of dermatological science 2011;61(3):187-93.
2011: Chikako Moriya; Masatoshi Jinnin; Keitaro Yamane; Keishi Maruo; Faith C Muchemwa; Toshikatsu Igata; Takamitsu Makino; Satoshi Fukushima; Hironobu Ihn
Expression of matrix metalloproteinase-13 is controlled by IL-13 via PI3K/Akt3 and PKC-δ in normal human dermal fibroblasts.
The Journal of investigative dermatology 2011;131(3):655-61.
2011: Yoshihide Asano; Hironobu Ihn; Masatoshi Jinnin; Kunihiko Tamaki; Shinichi Sato
Altered dynamics of transforming growth factor β(TGF-β) receptors in scleroderma fibroblasts.
Annals of the rheumatic diseases 2011;70(2):384-7.
2011: Masatoshi Jinnin; Yoshio Kawashita; Shinichi Masuguchi; Hiroki Tanaka; Satoshi Fukushima; Tsuyoshi Ishihara; Hironobu Ihn
Evaluation of usefulness of 3D views for clinical photography.
Bioscience trends 2011;5(5):211-6.
2011: Satoshi Fukushima; Hironobu Ihn; Yasuharu Nishimura; Satoru Senju
[Cancer immunotherapy by utilizing dedritic cells derived from pluripotent stem cells].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2011;34(3):113-20.
2011: Yoshio Kawashita; Masatoshi Jinnin; Takamitsu Makino; Ikko Kajihara; Katunari Makino; Noritoshi Honda; Shinich Masuguchi; Satoshi Fukushima; Yuji Inoue; Hironobu Ihn
Circulating miR-29a levels in patients with scleroderma spectrum disorder.
Journal of dermatological science 2011;61(1):67-9.
2010: Tomohiko Kawashima; Yayoi Tada; Yoshihide Asano; Norihito Yazawa; Manabu Tomita; Zenshiro Tamaki; Masahide Kubo; Hironobu Ihn; Makoto Sugaya; Takafumi Kadono; Kunihiko Tamaki; Shinichi Sato
Serum TARC/CCL17 levels are increased in dermatomyositis associated with interstitial lung disease.
Journal of dermatological science 2010;60(1):52-4.
2010: N Honda; Masatoshi Jinnin; I Kajihara; T Makino; S Fukushima; Hironobu Ihn
Impaired lymphangiogenesis due to excess vascular endothelial growth factor-D/Flt-4 signalling in the skin of patients with systemic sclerosis.
The British journal of dermatology 2010;163(4):776-80.
2010: Hiroshi Kato; Y Inoue; Tsuyoshi Ishihara; Toshiro Kageshita; Hironobu Ihn
Amelanotic malignant melanoma where primary lesion was discovered 5 years after metastasis in the lymph node.
The Journal of dermatology 2010;37(8):730-4.
2010: Faith C Muchemwa; Masatoshi Jinnin; Shoji Wakasugi; Maki Sakamoto; Yuji Inoue; Tsuyoshi Ishihara; Hironobu Ihn
A novel COL1A1 exon 14/PDGFB fusion gene in dermatofibrosarcoma protuberans.
European journal of dermatology : EJD 2010;20(3):390-1.
2010: Tatsuya Hoshino; Minoru Matsuda; Yasuhiro Yamashita; Masaya Takehara; Masayo Fukuya; Kazutaka Mineda; Daisuke Maji; Hironobu Ihn; Hiroaki Adachi; Gen Sobue; Yoko Funasaka; Tohru Mizushima
Suppression of melanin production by expression of HSP70.
The Journal of biological chemistry 2010;285(17):13254-63.
2010: Hazuki Nishi; Y Inoue; Toshiro Kageshita; Minoru Takata; Hironobu Ihn
The expression of human high molecular weight melanoma-associated antigen in acral lentiginous melanoma.
Bioscience trends 2010;4(2):86-9.
2010: T Makino; Masatoshi Jinnin; F C Muchemwa; S Fukushima; H Kogushi-Nishi; C Moriya; Tomohide Igata; A Fujisawa; T Johno; Hironobu Ihn
Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblasts via the ERK1/2 and JNK pathways.
The British journal of dermatology 2010;162(4):717-23.
2010: Masatoshi Jinnin; T Makino; I Kajihara; N Honda; K Makino; A Ogata; Hironobu Ihn
Serum levels of soluble vascular endothelial growth factor receptor-2 in patients with systemic sclerosis.
The British journal of dermatology 2010;162(4):751-8.
2010: F C Muchemwa; Shoji Wakasugi; Y Honda; Hironobu Ihn
PDGFB quantification is a useful tool in the diagnosis of dermatofibrosarcoma protuberans: a study of 10 cases.
Clinical and experimental dermatology 2010;35(3):295-9.
2010: Toshikatsu Igata; Masatoshi Jinnin; Takamitsu Makino; Chikako Moriya; Faith C Muchemwa; Tsuyoshi Ishihara; Hironobu Ihn
Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblasts.
Biochemical and biophysical research communications 2010;393(1):101-5.
2010: Minoru Matsuda; Tatsuya Hoshino; Yasuhiro Yamashita; Ken-ichiro Tanaka; Daisuke Maji; Keizo Sato; Hiroaki Adachi; Gen Sobue; Hironobu Ihn; Yoko Funasaka; Tohru Mizushima
Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.
The Journal of biological chemistry 2010;285(8):5848-58.
2010: Taiji Nakashima; Masatoshi Jinnin; Tomomi Etoh; Satoshi Fukushima; Shinichi Masuguchi; Keishi Maruo; Yuji Inoue; Tsuyoshi Ishihara; Hironobu Ihn
Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: its implications to therapy.
PloS one 2010;5(12):e14334.
2010: Nobuyo Higashi-Kuwata; Masatoshi Jinnin; Takamitsu Makino; Satoshi Fukushima; Yuji Inoue; Faith C Muchemwa; Yuji Yonemura; Yoshihiro Komohara; Motohiro Takeya; Hiroaki Mitsuya; Hironobu Ihn
Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis.
Arthritis research & therapy 2010;12(4):R128.
2009: Ryuichi Ashida; Hironobu Ihn; Yoshihiro Mimura; Masatoshi Jinnin; Yoshihide Asano; Masahide Kubo; Kunihiko Tamaki
Clinical and laboratory features of Japanese patients with scleroderma and telangiectasia.
Clinical and experimental dermatology 2009;34(7):781-3.
2009: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Retrospective study of clinical and laboratory features in Japanese scleroderma patients with cardiac involvement.
Journal of dermatological science 2009;55(1):70-2.
2009: Xiaoyong Zhang; Kiyofumi Egawa; Yong Xie; Hironobu Ihn
The expression of SnoN in normal human skin and cutaneous keratinous neoplasms.
International journal of dermatology 2009;48(6):579-83.
2009: Hazuki Kogushi-Nishi; Junko Kawasaki; Toshiro Kageshita; Tsuyoshi Ishihara; Hironobu Ihn
The prevalence of melanocytic nevi on the soles in the Japanese population.
Journal of the American Academy of Dermatology 2009;60(5):767-71.
2009: Satoshi Fukushima; Shinya Hirata; Yutaka Motomura; Daiki Fukuma; Yusuke Matsunaga; Yoshiaki Ikuta; Tokunori Ikeda; Toshiro Kageshita; Hironobu Ihn; Yasuharu Nishimura; Satoru Senju
Multiple antigen-targeted immunotherapy with alpha-galactosylceramide-loaded and genetically engineered dendritic cells derived from embryonic stem cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(3):219-31.
2009: Satoru Hashimoto; Kiyofumi Egawa; Hironobu Ihn; Satoshi Tateishi
Non-radioisotope method for diagnosing photosensitive genodermatoses and a new marker for xeroderma pigmentosum variant.
The Journal of dermatology 2009;36(3):138-43.
2009: Hironobu Ihn
[Systemic sclerosis].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(3):519-22.
2008: Tsuyoshi Ishihara; Shinichi Masuguchi; Hironobu Ihn
Using the smallest skin excision without dog-ear formations: utilizing histopathology on the face.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2008;34(10):1404-6.
2008: Yuri Masui; Mayumi Komine; Takafumi Kadono; Nobuko Ishiura; Takeo Maekawa; Hironobu Ihn; Kanako Kikuchi; Kunihiko Tamaki
Proliferating tricholemmal cystic carcinoma: a case containing differentiated and dedifferentiated parts.
Journal of cutaneous pathology 2008;35 Suppl 1():55-8.
2008: Hidehisa Saeki; Aya Watanabe; Yayoi Tada; Takashi Kakinuma; Mayumi Komine; Hironobu Ihn; Akihiko Asahina; Takafumi Etoh; Sachiko Kitanaka; Utako Sato; Hirotsugu Kano; Takashi Igarashi; Kunihiko Tamaki
Juvenile pustular psoriasis associated with steroid withdrawal syndrome due to topical corticosteroid.
The Journal of dermatology 2008;35(9):601-3.
2008: Hironobu Ihn
[Treatment of skin ulcers in collagen vascular diseases].
Nihon Hansenbyō Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 2008;77(3):211-3.
2008: Satoshi Fukushima; Masato Kidou; Hironobu Ihn
Fixed food eruption caused by cashew nut.
Allergology international : official journal of the Japanese Society of Allergology 2008;57(3):285-7.
2008: Keisuke Sakai; Shoji Wakasugi; Faith C Muchemwa; Hironobu Ihn
Quick detection of herpes viruses from skin vesicles and exudates without nucleic acid extraction using multiplex PCR.
Bioscience trends 2008;2(4):164-8.
2008: Faith Chengetayi Muchemwa; Tetsuya Nakatsura; Satoshi Fukushima; Yasuharu Nishimura; Toshiro Kageshita; Hironobu Ihn
Differential expression of heat shock protein 105 in melanoma and melanocytic naevi.
Melanoma research 2008;18(3):166-71.
2008: Yong Xie; Xiaoyong Zhang; Shoji Wakasugi; Takamitsu Makino; Y Inoue; Hironobu Ihn
Immunohistochemical characterization of the cellular infiltrate in localized scleroderma.
International journal of dermatology 2008;47(5):438-42.
2008: Yuichiro Yoshino; Toshiro Kageshita; Motowo Nakajima; Minako Funakubo; Hironobu Ihn
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
The Journal of dermatology 2008;35(4):206-14.
2008: Y Inoue; Tomomichi Ono; Tamano Matsui; Jiro Miyasaka; Yoshihiro Kinoshita; Hironobu Ihn
Epidemiological survey of Vibrio vulnificus infection in Japan between 1999 and 2003.
The Journal of dermatology 2008;35(3):129-39.
2008: Satoru Hashimoto; Kiyofumi Egawa; Hironobu Ihn; Ai Igarashi; Tsukasa Matsunaga; Satoshi Tateishi; Masaru Yamaizumi
A new disorder in UV-induced skin cancer with defective DNA repair distinct from xeroderma pigmentosum or Cockayne syndrome.
The Journal of investigative dermatology 2008;128(3):694-701.
2008: Koji Makino; Kazuaki Umeda; Akiyoshi Uezu; Yukari Hiragami; Tatsuhiko Sakamoto; Hironobu Ihn; Hiroyuki Nakanishi
Identification and characterization of the novel centrosomal protein centlein.
Biochemical and biophysical research communications 2008;366(4):958-62.
2008: F C Muchemwa; D Ma; Y Inoue; John A Curtin; Boris C Bastian; Hironobu Ihn; Toshiro Kageshita
Constitutive activation of the phosphatidyl inositol 3 kinase signalling pathway in acral lentiginous melanoma.
The British journal of dermatology 2008;158(2):411-3.
2008: Hironobu Ihn
Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis.
Journal of dermatological science 2008;49(2):103-13.
2008: Satoshi Fukushima; Kiyofumi Egawa; Hazuki Nishi; Shoji Wakasugi; Norito Ishii; Takashi Hashimoto; Kim B Yancey; Hironobu Ihn
Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy.
Acta dermato-venereologica 2008;88(5):484-7.
2008: Tsuyoshi Ishihara; Toshikatsu Igata; Shinichi Masuguchi; Shigeto Matsushita; Keisuke Sakai; Hironobu Ihn
Submental perforator flap: location and number of submental perforating vessels.
Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi 2008;42(3):127-31.
2008: Yong Xie; Xiaoyong Zhang; Yuji Inoue; Shouji Wakasugi; Takamitsu Makino; Hironobu Ihn
Expression of CD1a and CD86 on scleroderma Langerhans cells.
European journal of dermatology : EJD 2008;18(1):50-4.
2007: Xiaoyong Zhang; Takamitsu Makino; Faith C Muchemwa; Tong Lin; Shoji Wakasugi; Kiyofumi Egawa; Hironobu Ihn
Activation of the extracellular signal-regulated kinases signaling pathway in squamous cell carcinoma of the skin.
Bioscience trends 2007;1(3):156-60.
2007: Y Inoue; Jiro Miyasaka; Tomomichi Ono; Hironobu Ihn
The growth of Vibrio vulnificus and the habitat of infected patients in Kumamoto.
Bioscience trends 2007;1(3):134-9.
2007: Ryuichi Ashida; Hironobu Ihn; Yoshihiro Mimura; Masatoshi Jinnin; Yoshihide Asano; Masahide Kubo; Kunihiko Tamaki
Clinical features of scleroderma patients with contracture of phalanges.
Clinical rheumatology 2007;26(8):1275-7.
2007: Yoshihiro Mimura; Norihito Yazawa; Zenshirou Tamaki; Ryuichi Ashida; Masatoshi Jinnin; Yoshihide Asano; Yayoi Tada; Masahide Kubo; Hironobu Ihn; Kunihiko Tamaki
Anti-p53 antibodies in patients with dermatomyositis/polymyositis.
Clinical rheumatology 2007;26(8):1328-31.
2007: Yoshihide Asano; Hironobu Ihn; Kunihiko Tamaki
Linear connective tissue nevus.
Pediatric dermatology 2007;24(4):439-41.
2007: Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kunihiko Tamaki
Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts.
Arthritis and rheumatism 2007;56(5):1694-705.
2007: Hidehisa Saeki; Shusaku Hosono; Yuichiro Tsunemi; Kiyo Sasaki; Takafumi Kadono; Hironobu Ihn; Mayumi Komine; Akihiko Asahina; Kanako Kikuchi; Kunihiko Tamaki
Psoriasis vulgaris associated with superior vena cava syndrome due to lung cancer metastasis.
The Journal of dermatology 2007;34(5):356-9.
2007: Kenichi Yamane; Yoshihide Asano; Kunihiko Tamaki; Hironobu Ihn
Epidermal growth factor up-regulates transforming growth factor-beta receptor type II in human dermal fibroblasts via p38 mitogen-activated protein kinase pathway.
Biochemical and biophysical research communications 2007;352(1):69-77.
2007: Y Masui; Makoto Sugaya; Shinji Kagami; Hideki Fujita; Shoichiro Yano; M Nagao; Mayumi Komine; Hidehisa Saeki; Hironobu Ihn; Kanako Kikuchi; Kunihiko Tamaki
Sézary syndrome treated with narrowband ultraviolet B: time-course measurement of serum levels of CCL17/CCL27.
Clinical and experimental dermatology 2007;32(1):57-9.
2006: F C Muchemwa; Tetsuya Nakatsura; Hironobu Ihn; Toshiro Kageshita
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
The British journal of dermatology 2006;155(3):582-5.
2006: Hiroko Nakashima; Mayumi Komine; Kiyo Sasaki; Hiroshi Mitsui; Manabu Fujimoto; Hironobu Ihn; Akihiko Asahina; Kanako Kikuchi; Kunihiko Tamaki
Necrolytic migratory erythema without glucagonoma in a patient with short bowel syndrome.
The Journal of dermatology 2006;33(8):557-62.
2006: Yoshihide Asano; Hironobu Ihn; Masatoshi Jinnin; Yoshihiro Mimura; Kunihiko Tamaki
Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma.
The Journal of investigative dermatology 2006;126(8):1761-9.
2006: Yoshihide Asano; Hironobu Ihn; Masahide Kubo; Masatoshi Jinnin; Yoshihiro Mimura; Ryuichi Ashida; Kunihiko Tamaki
Clinical significance of serum matrix metalloproteinase-13 levels in patients with localized scleroderma.
Clinical and experimental rheumatology 2006;24(4):394-9.
2006: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Rheumatoid factor isotypes in mixed connective tissue disease.
Clinical rheumatology 2006;25(4):572-4.
2006: Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kunihiko Tamaki
Potential regulatory elements of the constitutive up-regulated alpha2(I) collagen gene in scleroderma dermal fibroblasts.
Biochemical and biophysical research communications 2006;343(3):904-9.
2006: Masahide Kubo; Hironobu Ihn; Kenichi Yamane; Kunihiko Tamaki
The expression levels and the differential expression of transforming growth factor-beta receptors in dermatofibroma and dermatofibrosarcoma protuberans.
The British journal of dermatology 2006;154(5):919-25.
2006: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Epidermal growth factor affects the synthesis and degradation of type I collagen in cultured human dermal fibroblasts.
Matrix biology : journal of the International Society for Matrix Biology 2006;25(4):202-12.
2006: Yoshihide Asano; Hironobu Ihn; Takeo Maekawa; Takafumi Kadono; Kunihiko Tamaki
High-dose intravenous immunoglobulin infusion in polyarteritis nodosa: report on one case and review of the literature.
Clinical rheumatology 2006;25(3):396-8.
2006: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Maria Trojanowska; Kunihiko Tamaki
Upregulation of tenascin-C expression by IL-13 in human dermal fibroblasts via the phosphoinositide 3-kinase/Akt and the protein kinase C signaling pathways.
The Journal of investigative dermatology 2006;126(3):551-60.
2006: Yoshihide Asano; Hironobu Ihn; Masahide Kubo; Masatoshi Jinnin; Yoshihiro Mimura; Ryuichi Ashida; Kunihiko Tamaki
Clinical significance of serum levels of matrix metalloproteinase-13 in patients with systemic sclerosis.
Rheumatology (Oxford, England) 2006;45(3):303-7.
2006: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Maria Trojanowska; Kunihiko Tamaki
Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors.
Journal of cellular physiology 2006;206(3):718-27.
2006: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masatoshi Jinnin; Kunihiko Tamaki
Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts.
The American journal of pathology 2006;168(2):499-510.
2006: Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Masatoshi Jinnin; Kunihiko Tamaki
Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts.
Rheumatology (Oxford, England) 2006;45(2):157-65.
2006: Masatoshi Jinnin; Hironobu Ihn; Kunihiko Tamaki
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression.
Molecular pharmacology 2006;69(2):597-607.
2005: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masatoshi Jinnin; Yoshihiro Mimura; Kunihiko Tamaki
Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7708-18.
2005: Yoshihiro Mimra; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Anti-agalactosyl immunoglobulin G antibodies in localized scleroderma.
International journal of dermatology 2005;44(10):817-20.
2005: Yoshihde Asano; Hironobu Ihn; Kenichi Yamane; Masatoshi Jinnin; Yoshihiro Mimura; Kunihiko Tamaki
Involvement of alphavbeta5 integrin-mediated activation of latent transforming growth factor beta1 in autocrine transforming growth factor beta signaling in systemic sclerosis fibroblasts.
Arthritis and rheumatism 2005;52(9):2897-905.
2005: Yuichiro Tsunemi; Hironobu Ihn; Hideki Fujita; Nobuko Asashima; Hidehisa Saeki; Kunihiko Tamaki
Square-shaped scleredema in the back: probably induced by mechanical stress.
International journal of dermatology 2005;44(9):769-70.
2005: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Sclerosing panniculitis is associated with pulmonary hypertension in systemic sclerosis.
The British journal of dermatology 2005;153(3):579-83.
2005: Hironobu Ihn; Kenichi Yamane; Kunihiko Tamaki
Increased phosphorylation and activation of mitogen-activated protein kinase p38 in scleroderma fibroblasts.
The Journal of investigative dermatology 2005;125(2):247-55.
2005: Yuichiro Tsunemi; Kiyo Shimazu; Hidehisa Saeki; Hironobu Ihn; Kunihiko Tamaki
Eccrine angiomatous hamartoma with massive mucin deposition.
European journal of dermatology : EJD 2005;15(4):291-2.
2005: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Rheumatoid factor isotypes in localized scleroderma.
Clinical and experimental dermatology 2005;30(4):405-8.
2005: Y Asano; Hironobu Ihn; Nobuko Asashima; Norihito Yazawa; Y Mimura; Masatoshi Jinnin; K Yamane; Kunihiko Tamaki
A case of diffuse scleroderma successfully treated with high-dose intravenous immune globulin infusion.
Rheumatology (Oxford, England) 2005;44(6):824-6.
2005: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Constitutive thrombospondin-1 overexpression contributes to autocrine transforming growth factor-beta signaling in cultured scleroderma fibroblasts.
The American journal of pathology 2005;166(5):1451-63.
2005: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Constitutive phosphorylation of focal adhesion kinase is involved in the myofibroblast differentiation of scleroderma fibroblasts.
The Journal of investigative dermatology 2005;124(5):886-92.
2005: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masatoshi Jinnin; Yoshihiro Mimura; Kunihiko Tamaki
Differential effects of the immunosuppressant FK-506 on human alpha2(I) collagen gene expression and transforming growth factor beta signaling in normal and scleroderma fibroblasts.
Arthritis and rheumatism 2005;52(4):1237-47.
2005: Hironobu Ihn
Scleroderma, fibroblasts, signaling, and excessive extracellular matrix.
Current rheumatology reports 2005;7(2):156-62.
2005: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Clinical and laboratory features of scleroderma patients developing skeletal myopathy.
Clinical rheumatology 2005;24(2):99-102.
2005: Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Effects of hepatocyte growth factor on the expression of type I collagen and matrix metalloproteinase-1 in normal and scleroderma dermal fibroblasts.
The Journal of investigative dermatology 2005;124(2):324-30.
2005: Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Regulation of fibrogenic/fibrolytic genes by platelet-derived growth factor C, a novel growth factor, in human dermal fibroblasts.
Journal of cellular physiology 2005;202(2):510-7.
2005: Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1.
Nucleic acids research 2005;33(11):3540-9.
2005: Hiroko Nakashima; K Yamane; Hironobu Ihn; Kozo Nakamura; Rei Watanabe; Yoshihiro Kuwano; Tomonori Takekoshi; T Watanabe; Naoko Hattori; Manabu Fujimoto; Kunihiko Tamaki
Drug-induced hypersensitivity syndrome associated with transient hypogammaglobulinaemia and increase in serum IgE level.
Dermatology (Basel, Switzerland) 2005;210(4):349-52.
2005: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Yoshihiro Mimura; Yoshihide Asano; Kunihiko Tamaki
Alpha2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts.
Nucleic acids research 2005;33(4):1337-51.
2004: Nobuko Asashima; Manabu Fujimoto; Masatoshi Jinnin; Hironobu Ihn; Kanako Kikuchi; Masaru Takamizawa; Kunihiko Tamaki
[A female case of hyper-IgM immunodeficiency syndrome with uncommon skin manifestations].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2004;27(5):350-5.
2004: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Rheumatoid factor isotypes and anti-agalactosyl IgG antibodies in systemic sclerosis.
The British journal of dermatology 2004;151(4):803-8.
2004: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Kunihiko Tamaki
Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts.
The Journal of biological chemistry 2004;279(40):41783-91.
2004: Yuichiro Tsunemi; Y Tada; Hidehisa Saeki; Hironobu Ihn; Kunihiko Tamaki
Multiple dermatofibromas in a patient with systemic lupus erythematosus and Sjögren's syndrome.
Clinical and experimental dermatology 2004;29(5):483-5.
2004: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Serum levels of tissue inhibitor of metalloproteinase-1 and 2 in patients with eosinophilic fasciitis.
The British journal of dermatology 2004;151(2):407-12.
2004: Yuichiro Tsunemi; Hironobu Ihn; Hidehisa Saeki; Kunihiko Tamaki
The lesional skin of linear IgA bullous dermatosis expresses growth-regulated peptide (GRO)-alpha.
The Journal of dermatology 2004;31(7):546-51.
2004: Masako Sato-Takeda; Hironobu Ihn; Jun Ohashi; Naoyuki Tsuchiya; Masahiro Satake; Hideko Arita; Kunihiko Tamaki; Kazuo Hanaoka; Katsushi Tokunaga; Toshio Yabe
The human histocompatibility leukocyte antigen (HLA) haplotype is associated with the onset of postherpetic neuralgia after herpes zoster.
Pain 2004;110(1-2):329-36.
2004: Masatoshi Jinnin; Hironobu Ihn; Norihito Yazawa; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Serum levels of manganese superoxide dismutase in patients with localized scleroderma.
Experimental dermatology 2004;13(6):357-60.
2004: Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C delta signaling pathway.
The Journal of investigative dermatology 2004;122(6):1390-8.
2004: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masatoshi Jinnin; Yoshihiro Mimura; Kunihiko Tamaki
Phosphatidylinositol 3-kinase is involved in alpha2(I) collagen gene expression in normal and scleroderma fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7123-35.
2004: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Serum matrix metalloproteinase-3 in systemic sclerosis.
Archives of dermatological research 2004;296(1):25-9.
2004: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masahide Kubo; Kunihiko Tamaki
Increased expression levels of integrin alphavbeta5 on scleroderma fibroblasts.
The American journal of pathology 2004;164(4):1275-92.
2004: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Maria Trojanowska; Kunihiko Tamaki
Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1.
Oncogene 2004;23(9):1656-67.
2004: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masahide Kubo; Kunihiko Tamaki
Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts.
The Journal of clinical investigation 2004;113(2):253-64.
2003: Hironobu Ihn
[The pathogenesis of fibrosis in scleroderma].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2003;26(5):274-82.
2003: Kenichi Yamane; Hironobu Ihn; Yoshihide Asano; Masatoshi Jinnin; Kunihiko Tamaki
Antagonistic effects of TNF-alpha on TGF-beta signaling through down-regulation of TGF-beta receptor type II in human dermal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(7):3855-62.
2003: Kenichi Yamane; Hironobu Ihn; Kunihiko Tamaki
Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblasts.
Arthritis and rheumatism 2003;48(6):1652-66.
2003: Yuichiro Tsunemi; Hironobu Ihn; K Nakamura; Kunihiko Tamaki
Post-transplantation chronic graft-versus-host disease with overlapping features similar to those of various collagen diseases.
International journal of dermatology 2003;42(4):292-4.
2003: Masatoshi Jinnin; Hironobu Ihn; Norihito Yazawa; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki
Elevated circulating soluble CD40 ligand in patients with mixed connective tissue disease.
Clinical rheumatology 2003;22(1):37-9.
2003: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Plasma plasmin-alpha2-plasmin inhibitor complex levels are increased in systemic sclerosis patients with pulmonary hypertension.
Rheumatology (Oxford, England) 2003;42(2):240-3.
2003: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Masahide Kubo; Kunihiko Tamaki
The prevalence and clinical significance of anti-U1 RNA antibodies in patients with systemic sclerosis.
The Journal of investigative dermatology 2003;120(2):204-10.
2003: Yuichiro Tsunemi; Hironobu Ihn; Naoko Hattori; Hidehisa Saeki; Kunihiko Tamaki
Multiple eruptive dermatofibromas with CD34+ cells in a patient with hypertriglyceridemia.
Dermatology (Basel, Switzerland) 2003;207(3):319-21.
2003: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Clinical features of patients with systemic sclerosis accompanied by rheumatoid arthritis.
Clinical and experimental rheumatology 2003;21(1):91-4.
2002: Masahide Kubo; Hironobu Ihn; Kenichi Yamane; Kunihiko Tamaki
Upregulated expression of transforming growth factor-beta receptors in dermal fibroblasts of skin sections from patients with systemic sclerosis.
The Journal of rheumatology 2002;29(12):2558-64.
2002: Hironobu Ihn; Yoshihide Asano; Masahide Kubo; Kenichi Yamane; Masatoshi Jinnin; Norihito Yazawa; Manabu Fujimoto; Kunihiko Tamaki
Clinical significance of serum surfactant protein D (SP-D) in patients with polymyositis/dermatomyositis: correlation with interstitial lung disease.
Rheumatology (Oxford, England) 2002;41(11):1268-72.
2002: Hironobu Ihn
Pathogenesis of fibrosis: role of TGF-beta and CTGF.
Current opinion in rheumatology 2002;14(6):681-5.
2002: Hironobu Ihn; Kunihiko Tamaki
Mitogenic activity of dermatofibrosarcoma protuberans is mediated via an extracellular signal related kinase dependent pathway.
The Journal of investigative dermatology 2002;119(4):954-60.
2002: Kenichi Yamane; Hironobu Ihn; Masahide Kubo; Kunihiko Tamaki
Increased transcriptional activities of transforming growth factor beta receptors in scleroderma fibroblasts.
Arthritis and rheumatism 2002;46(9):2421-8.
2002: Masatoshi Jinnin; Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Serum levels of tissue inhibitor of metalloproteinases in patients with mixed connective tissue disease.
Clinical and experimental rheumatology 2002;20(4):539-42.
2002: Masahide Kubo; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Prevalence of 52-kd and 60-kd Ro/SS-A autoantibodies in Japanese patients with polymyositis/dermatomyositis.
Journal of the American Academy of Dermatology 2002;47(1):148-51.
2002: Masatoshi Jinnin; Hironobu Ihn; Yoshihide Asano; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
A case of linear scleroderma with muscle calcification.
The British journal of dermatology 2002;146(6):1084-6.
2002: Masahide Kubo; Hironobu Ihn; M Kuwana; Yoshihide Asano; T Tamaki; Kenichi Yamane; Kunihiko Tamaki
Anti-U5 snRNP antibody as a possible serological marker for scleroderma-polymyositis overlap.
Rheumatology (Oxford, England) 2002;41(5):531-4.
2002: Hironobu Ihn; Kenichi Yamane; Yoshihide Asano; Masahide Kubo; Kunihiko Tamaki
IL-4 up-regulates the expression of tissue inhibitor of metalloproteinase-2 in dermal fibroblasts via the p38 mitogen-activated protein kinase dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1895-902.
2002: Hironobu Ihn
The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma.
Archivum immunologiae et therapiae experimentalis 2002;50(5):325-31.
2001: Masahide Kubo; Hironobu Ihn; M Kuwana; Kenichi Yamane; Norihito Yazawa; Kunihiko Tamaki
Prevalence in myositis of antibodies recognizing anti-U3 RNA probably in a novel complex with 22/25 kD protein and not fibrillarin.
Clinical and experimental immunology 2001;126(2):339-44.
2001: Kenichi Yamane; Hironobu Ihn; Masahide Kubo; M Kuwana; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Anti-U1RNP antibodies in patients with localized scieroderma.
Archives of dermatological research 2001;293(9):455-9.
2001: Kenichi Yamane; Hironobu Ihn; Masahide Kubo; M Kuwana; Yoshihide Asano; Norihito Yazawa; Kunihiko Tamaki
Antibodies to Th/To ribonucleoprotein in patients with localized scleroderma.
Rheumatology (Oxford, England) 2001;40(6):683-6.
2001: Yoshihide Asano; Hironobu Ihn; Kenichi Yamane; Norihito Yazawa; Masahide Kubo; Manabu Fujimoto; Kunihiko Tamaki
Clinical significance of surfactant protein D as a serum marker for evaluating pulmonary fibrosis in patients with systemic sclerosis.
Arthritis and rheumatism 2001;44(6):1363-9.
2001: Masahide Kubo; Hironobu Ihn; Kenichi Yamane; Kunihiko Tamaki
Up-regulated expression of transforming growth factor beta receptors in dermal fibroblasts in skin sections from patients with localized scleroderma.
Arthritis and rheumatism 2001;44(3):731-4.
2001: Hironobu Ihn; Kenichi Yamane; Masahide Kubo; Kunihiko Tamaki
Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors.
Arthritis and rheumatism 2001;44(2):474-80.
2001: Norihito Yazawa; Hironobu Ihn; K Yamane; T Etoh; Kunihiko Tamaki
The successful treatment of prurigo pigmentosa with macrolide antibiotics.
Dermatology (Basel, Switzerland) 2001;202(1):67-9.
2000: Kenichi Yamane; Hironobu Ihn; Yoshihide Asano; Norihito Yazawa; Masahide Kubo; Kanako Kikuchi; Y Soma; Kunihiko Tamaki
Clinical and laboratory features of scleroderma patients with pulmonary hypertension.
Rheumatology (Oxford, England) 2000;39(11):1269-71.
2000: Hironobu Ihn; Kunihiko Tamaki
Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: association with increased expression of the type I collagen gene.
Arthritis and rheumatism 2000;43(10):2240-7.
2000: Hironobu Ihn; Kunihiko Tamaki
Oncostatin M stimulates the growth of dermal fibroblasts via a mitogen-activated protein kinase-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):2149-55.
2000: Masahide Kubo; Hironobu Ihn; Kenichi Yamane; Norihito Yazawa; Kanako Kikuchi; Y Soma; Kunihiko Tamaki
Increased serum levels of soluble vascular cell adhesion molecule-1 and soluble E-selectin in patients with polymyositis/dermatomyositis.
The British journal of dermatology 2000;143(2):392-8.
2000: Masahide Kubo; Hironobu Ihn; Kenichi Yamane; Kanako Kikuchi; Norihito Yazawa; Y Soma; Kunihiko Tamaki
Serum KL-6 in adult patients with polymyositis and dermatomyositis.
Rheumatology (Oxford, England) 2000;39(6):632-6.
2000: Hironobu Ihn; Kunihiko Tamaki
Competition analysis of the human alpha2(I) collagen promoter using synthetic oligonucleotides.
The Journal of investigative dermatology 2000;114(5):1011-6.
2000: Kenichi Yamane; Hironobu Ihn; Masahide Kubo; Norihito Yazawa; Kanako Kikuchi; Y Soma; Kunihiko Tamaki
Serum levels of KL-6 as a useful marker for evaluating pulmonary fibrosis in patients with systemic sclerosis.
The Journal of rheumatology 2000;27(4):930-4.
2000: Hironobu Ihn; Norihito Yazawa; Masahide Kubo; Kenichi Yamane; Shinichi Sato; Manabu Fujimoto; Kanako Kikuchi; Y Soma; Kunihiko Tamaki
Circulating levels of soluble CD30 are increased in patients with localized scleroderma and correlated with serological and clinical features of the disease.
The Journal of rheumatology 2000;27(3):698-702.
2000: Norihito Yazawa; Kanako Kikuchi; Hironobu Ihn; Manabu Fujimoto; Masahide Kubo; T Tamaki; Kunihiko Tamaki
Serum levels of tissue inhibitor of metalloproteinases 2 in patients with systemic sclerosis.
Journal of the American Academy of Dermatology 2000;42(1 Pt 1):70-5.
2000: Kenichi Yamane; Hironobu Ihn; Masahide Kubo; Norihito Yazawa; Kanako Kikuchi; Y Soma; Kunihiko Tamaki
Increased serum levels of soluble vascular cell adhesion molecule 1 and E-selectin in patients with localized scleroderma.
Journal of the American Academy of Dermatology 2000;42(1 Pt 1):64-9.
2000: Hironobu Ihn; Shinichi Sato; M Fujimoto; A Igarashi; Norihito Yazawa; Masahide Kubo; K Kikuchi; K Takehara; Kunihiko Tamaki
Characterization of autoantibodies to endothelial cells in systemic sclerosis (SSc): association with pulmonary fibrosis.
Clinical and experimental immunology 2000;119(1):203-9.
1999: Hironobu Ihn; Kenichi Yamane; Norihito Yazawa; Masahide Kubo; M Fujimoto; Shinichi Sato; K Kikuchi; Kunihiko Tamaki
Distribution and antigen specificity of anti-U1RNP antibodies in patients with systemic sclerosis.
Clinical and experimental immunology 1999;117(2):383-7.
1999: Masahide Kubo; Hironobu Ihn; A Matsukawa; Kanako Kikuchi; Kunihiko Tamaki
Dermatomyositis with elevated serum hyaluronate.
Clinical and experimental dermatology 1999;24(4):275-8.
1999: Masahide Kubo; Hironobu Ihn; Norihito Yazawa; Shinichi Sato; Kanako Kikuchi; Kunihiko Tamaki
Prevalence and antigen specificity of anti-histone antibodies in patients with polymyositis/dermatomyositis.
The Journal of investigative dermatology 1999;112(5):711-5.
1998: Kanako Kikuchi; Masahide Kubo; T Kadono; Norihito Yazawa; Hironobu Ihn; Kunihiko Tamaki
Serum concentrations of vascular endothelial growth factor in collagen diseases.
The British journal of dermatology 1998;139(6):1049-51.
1998: Hironobu Ihn; Shinichi Sato; Manabu Fujimoto; K Takehara; Kunihiko Tamaki
Increased serum levels of soluble vascular cell adhesion molecule-1 and E-selectin in patients with systemic sclerosis.
British journal of rheumatology 1998;37(11):1188-92.
1998: Norihito Yazawa; Manabu Fujimoto; Kanako Kikuchi; Masahide Kubo; Hironobu Ihn; Shinichi Sato; T Tamaki; Kunihiko Tamaki
High seroprevalence of Helicobacter pylori infection in patients with systemic sclerosis: association with esophageal involvement.
The Journal of rheumatology 1998;25(4):650-3.
1998: T Kadono; Kanako Kikuchi; Hironobu Ihn; K Takehara; Kunihiko Tamaki
Increased production of interleukin 6 and interleukin 8 in scleroderma fibroblasts.
The Journal of rheumatology 1998;25(2):296-301.
1997: Manabu Fujimoto; Kanako Kikuchi; T Tamaki; Norihito Yazawa; Masahide Kubo; Hironobu Ihn; Shinichi Sato; Y Soma; Kunihiko Tamaki
Distribution of anti-p80-coilin autoantibody in collagen diseases and various skin diseases.
The British journal of dermatology 1997;137(6):916-20.
1997: Hironobu Ihn; Shinichi Sato; Manabu Fujimoto; K Kikuchi; T Kadono; Kunihiko Tamaki; K Takehara
Circulating intercellular adhesion molecule-1 in the sera of patients with systemic sclerosis: enhancement by inflammatory cytokines.
British journal of rheumatology 1997;36(12):1270-5.
1997: Manabu Fujimoto; M Shimozuma; N Yazawa; M Kubo; Hironobu Ihn; Shinichi Sato; T Tamaki; K Kikuchi; Kunihiko Tamaki
Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis.
Annals of the rheumatic diseases 1997;56(11):667-70.