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Takashi Iida

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lee hagey; Alan F Hofmann; Shigeo Ikegawa; Narimi Kato; Kuniko Mitamura; Shoujiro Ogawa; Rika Satoh née Okihara; Mizuho Une; Takashi Iida
A novel varanic acid epimer--(24R,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-27-oic acid--is a major biliary bile acid in two varanid lizards and the Gila monster.
Kuniko Mitamura; Kaori Nagae; Masataka Nakajima; Shoujiro Ogawa; Kanta Sato; Rika Satoh née Okihara; Sachi Fujioka; Alan F Hofmann; Takashi Iida; Takayuki Mabuchi; Rina Matsumoto; Shigeo Ikegawa
Synthesis of multiply deuterated 3- and 21-monosulfates of allo-tetrahydrocorticosteroids as internal standards for mass spectrometry.
Kuniko Mitamura; Shiori Mino; Alan F Hofmann; Naohiro Hori; Takashi Iida; Shigeo Ikegawa
Synthesis of the 3-sulfates of S-acyl glutathione conjugated bile acids and their biotransformation by a rat liver cytosolic fraction.

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2012: lee hagey; Alan F Hofmann; Shigeo Ikegawa; Narimi Kato; Kuniko Mitamura; Shoujiro Ogawa; Rika Satoh née Okihara; Mizuho Une; Takashi Iida
A novel varanic acid epimer--(24R,25S)-3α,7α,12α,24-tetrahydroxy-5β-cholestan-27-oic acid--is a major biliary bile acid in two varanid lizards and the Gila monster.
Steroids 2012;77(13):1510-21.
2012: Kuniko Mitamura; Kaori Nagae; Masataka Nakajima; Shoujiro Ogawa; Kanta Sato; Rika Satoh née Okihara; Sachi Fujioka; Alan F Hofmann; Takashi Iida; Takayuki Mabuchi; Rina Matsumoto; Shigeo Ikegawa
Synthesis of multiply deuterated 3- and 21-monosulfates of allo-tetrahydrocorticosteroids as internal standards for mass spectrometry.
Steroids 2012;77(13):1423-37.
2012: Kuniko Mitamura; Shiori Mino; Alan F Hofmann; Naohiro Hori; Takashi Iida; Shigeo Ikegawa
Synthesis of the 3-sulfates of S-acyl glutathione conjugated bile acids and their biotransformation by a rat liver cytosolic fraction.
Chemistry and physics of lipids 2012;165(3):261-9.
2012: Megumi Furukawa; Takashi Iida; Toru Imohata; Mitsuko Makino; Shoujiro Ogawa; Naoki Oikawa; Yasuo Fujimoto; Susumu Kitanaka
Monoterpene glucosides from Ziziphora clinopodioides (Labiatae).
Chemical & pharmaceutical bulletin 2012;60(3):397-401.
2011: Kuniko Mitamura; Hiroshi Nittono; Toshiaki Shimizu; Mitsuyoshi Suzuki; Kyoichi Takaori; Hajime Takikawa; Alan F Hofmann; Naohiro Hori; Takashi Iida; Shigeo Ikegawa
Identification of S-acyl glutathione conjugates of bile acids in human bile by means of LC/ESI-MS.
Steroids 2011;76(14):1609-14.
2011: Shigeo Ikegawa; Takayuki Mabuchi; Toshie Minematsu; Maki Hasegawa; Takashi Iida; Kaori Nagae; Rika Okihara; Kuniko Mitamura
Synthesis of 3- and 21-monosulfates of [2,2,3β,4,4-²H₅]-tetrahydrocorticosteroids in the 5β-series as internal standards for mass spectrometry.
Steroids 2011;76(12):1232-40.
2011: lee hagey; Yuuki Adachi; Takashi Iida; Masamitsu Maekawa; Nariyasu Mano; Kumiko Mushiake; Shoujiro Ogawa; Miki Shimada; Mizuho Une; Alan F Hofmann
Biliary bile acids in birds of the Cotingidae family: taurine-conjugated (24R,25R)-3α,7α,24-trihydroxy-5β-cholestan-27-oic acid and two epimers (25R and 25S) of 3α,7α-dihydroxy-5β-cholestan-27-oic acid.
Steroids 2011;76(10-11):1126-35.
2011: Shoujiro Ogawa; lee hagey; Alan F Hofmann; Shigeo Ikegawa; Matthew D Krasowski; Kuniko Mitamura; Takashi Iida
Chemical synthesis of the (25R)- and (25S)-epimers of 3α,7α,12α-trihydroxy-5α-cholestan-27-oic acid as well as their corresponding glycine and taurine conjugates.
Chemistry and physics of lipids 2011;164(5):368-77.
2011: Kuniko Mitamura; Eriko Aoyama; Toshihiro Sakai; Takashi Iida; Alan F Hofmann; Shigeo Ikegawa
Characterization of non-enzymatic acylation of amino or thiol groups of bionucleophiles by the acyl-adenylate or acyl-CoA thioester of cholic acid.
Analytical and bioanalytical chemistry 2011;400(7):2253-9.
2011: Kuniko Mitamura; Toshihiro Sakai; Risa Nakai; Tateaki Wakamiya; Takashi Iida; Alan F Hofmann; Shigeo Ikegawa
Synthesis of the 3-sulfates of N-acetylcysteine conjugated bile acids (BA-NACs) and their transient formation from BA-NACs and subsequent hydrolysis by a rat liver cytosolic fraction as shown by liquid chromatography/electrospray ionization-mass spectrometry.
Analytical and bioanalytical chemistry 2011;400(7):2061-72.
2011: Takashi Iida; Shoujiro Ogawa; Hideyuki Tamegai; Yuuki Adachi; Hiroaki Saito; Shigeo Ikegawa; Hiroaki Konishi; Akimitsu Takagi; Takeshi Matsuzaki
Chemical synthesis of the 17-propanamide derivatives of stereoisomeric Δ14-17α- and 17β-estradiols: potential 17β-hydroxysteroid dehydrogenase inhibitors.
Chemistry and physics of lipids 2011;164(2):106-12.
2011: Megumi Furukawa; Takashi Iida; Mitsuko Makino; Shoujiro Ogawa; Hideya Suzuki; Yasuo Fujimoto
Studies on the constituents of Lagochilus leiacanthus (Labiatae).
Chemical & pharmaceutical bulletin 2011;59(12):1535-40.
2011: Kuniko Mitamura; Naohiro Hori; Takashi Iida; Alan F Hofmann; Shigeo Ikegawa
Identification of bile acid S-acyl glutathione conjugates in rat bile by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
Steroids 2011;76(1-2):68-77.
2010: Shoujiro Ogawa; Yuuki Adachi; Genta Kakiyama; Miki Shimada; Nariyasu Mano; Junichi Goto; Takashi Iida
Chemical synthesis of (22E)-3alpha,6alpha,7alpha,12alpha-Tetrahydroxy-5beta-chol-22-en-24-oic acid and its N-acylamidated conjugates with glycine or taurine: precursors of the [22,23-(3)H] labelled tracers.
Chemical & pharmaceutical bulletin 2010;58(8):1103-6.
2010: Rika Okihara; Kuniko Mitamura; Maki Hasegawa; Megumi Mori; Akina Muto; Genta Kakiyama; Shoujiro Ogawa; Takashi Iida; Miki Shimada; Nariyasu Mano; Shigeo Ikegawa
Potential corticoid metabolites: chemical synthesis of 3- and 21-monosulfates and their double-conjugates of tetrahydrocorticosteroids in the 5alpha- and 5beta-series.
Chemical & pharmaceutical bulletin 2010;58(3):344-53.
2010: Shoujiro Ogawa; Yasuo Wakatsuki; Mitsuko Makino; Yasuo Fujimoto; Ken Yasukawa; Takashi Kikuchi; Motohiko Ukiya; Toshihiro Akihisa; Takashi Iida
Oxyfunctionalization of unactivated C-H bonds in triterpenoids with tert-butylhydroperoxide catalyzed by meso-5,10,15,20-tetramesitylporphyrinate osmium(II) carbonyl complex.
Chemistry and physics of lipids 2010;163(2):165-71.
2009: Genta Kakiyama; Akina Muto; Miki Shimada; Nariyasu Mano; Junichi Goto; Alan F Hofmann; Takashi Iida
Chemical synthesis of 3beta-sulfooxy-7beta-hydroxy-24-nor-5-cholenoic acid: an internal standard for mass spectrometric analysis of the abnormal delta5-bile acids occurring in Niemann-Pick disease.
Steroids 2009;74(9):766-72.
2009: lee hagey; Genta Kakiyama; Akina Muto; Takashi Iida; Kumiko Mushiake; Takaaki Goto; Nariyasu Mano; Junichi Goto; Cleida A Oliveira; Alan F Hofmann
A new, major C27 biliary bile acid in the red-winged tinamou (Rhynchotus rufescens):25R-1beta, 3alpha,7alpha-trihydroxy-5beta-cholestan-27-oic acid.
Journal of lipid research 2009;50(4):651-7.
2008: Mitsuko Makino; Taketo Uchiyama; Hiroaki Saito; Shoujiro Ogawa; Takashi Iida; Takao Katase; Yasuo Fujimoto
Separation, synthesis and estrogenic activity of 4-nonylphenols: two sets of new diastereomeric isomers in a commercial mixture.
Chemosphere 2008;73(8):1188-93.
2007: Genta Kakiyama; Hideyuki Tamegai; Takashi Iida; Kuniko Mitamura; Shigeo Ikegawa; Takaaki Goto; Nariyasu Mano; Junichi Goto; Peter Holz; lee hagey; Alan F Hofmann
Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15alpha-hydroxylithocholic acid.
Journal of lipid research 2007;48(12):2682-92.
2007: Takashi Iida; Shoujiro Ogawa; Keiji Hosoi; Mitsuko Makino; Yasuo Fujimoto; Takaaki Goto; Nariyasu Mano; Junichi Goto; Alan F Hofmann
Regioselective oxyfunctionalization of unactivated carbons in steroids by a model of cytochrome P-450: osmiumporphyrin complex/tert-butyl hydroperoxide system.
The Journal of organic chemistry 2007;72(3):823-30.
2007: Shoujiro Ogawa; Keiji Hosoi; Noriaki Ikeda; Mitsuko Makino; Yasuo Fujimoto; Takashi Iida
Oxyfunctionalization products of terpenoids with dimethyldioxirane and their biological activity.
Chemical & pharmaceutical bulletin 2007;55(2):247-50.
2007: Takaaki Goto; Khin Than Myint; Koichi Sato; Osamu Wada; Genta Kakiyama; Takashi Iida; Takanori Hishinuma; Nariyasu Mano; Junichi Goto
LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;846(1-2):69-77.
2006: Genta Kakiyama; Atsuko Hosoda; Takashi Iida; Yasuo Fujimoto; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
A direct method for the separation and quantification of bile acid acyl glycosides by high-performance liquid chromatography with an evaporative light scattering detector.
Journal of chromatography. A 2006;1125(1):112-6.
2006: Genta Kakiyama; Takashi Iida; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara; lee hagey; Claudio D Schteingart; Alan F Hofmann
Identification of a novel bile acid in swans, tree ducks, and geese: 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid.
Journal of lipid research 2006;47(7):1551-8.
2006: Genta Kakiyama; Shoujiro Ogawa; Takashi Iida; Yasuo Fujimoto; Kumiko Mushiake; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
Nuclear magnetic resonance spectroscopy of 3 beta,7 beta-dihydroxy-5-cholen-24-oic acid multi-conjugates: unusual bile acid metabolites in human urine.
Chemistry and physics of lipids 2006;140(1-2):48-54.
2006: Takashi Iida; Genta Kakiyama; Yohei Hibiya; Shohei Miyata; Takehiko Inoue; Kohsaku Ohno; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara; Alan F Hofmann
Chemical synthesis of the 3-sulfooxy-7-N-acetylglucosaminyl-24-amidated conjugates of 3beta,7beta-dihydroxy-5-cholen-24-oic acid, and related compounds: unusual, major metabolites of bile acid in a patient with Niemann-Pick disease type C1.
Steroids 2006;71(1):18-29.
2005: Tomoharu Okouchi; Tetsuya Abe; Shusuke Araki; Shinsuke Arai; Takashi Iida; Li-Yan Wang; Susumu Kitanaka; Shohei Miyata
Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds.
Bioorganic & medicinal chemistry 2005;13(11):3847-51.
2005: Genta Kakiyama; Shinji Sadakiyo; Takashi Iida; Kumiko Mushiake; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
Chemical synthesis of 24-beta-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine.
Chemistry and physics of lipids 2005;134(2):141-50.
2005: Takaaki Goto; Akihiro Shibata; Daisuke Sasaki; Naoto Suzuki; Takanori Hishinuma; Genta Kakiyama; Takashi Iida; Nariyasu Mano; Junichi Goto
Identification of a novel conjugate in human urine: bile acid acyl galactosides.
Steroids 2005;70(3):185-92.
2004: Takashi Iida; Shoujiro Ogawa; Genta Kakiyama; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
Capillary gas chromatographic separation of bile acid acyl glycosides without thermal decomposition and isomerization.
Journal of chromatography. A 2004;1057(1-2):171-6.
2004: Shoujiro Ogawa; Takashi Iida; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
The remote-oxyfunctionalization of unactivated carbons in (5 beta)-3-oxobile acids by 2,6-dichloropyridine N-oxide catalyzed by ruthenium-porphyrin and HBr: a direct lactonization at C-20.
Organic & biomolecular chemistry 2004;2(7):1013-8.
2004: Genta Kakiyama; Takashi Iida; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
Synthesis of 3alpha,7alpha,14alpha-trihydroxy-5beta-cholan-24-oic acid: a potential primary bile acid in vertebrates.
Chemical & pharmaceutical bulletin 2004;52(3):371-4.
2004: Genta Kakiyama; Takashi Iida; Atsushi Yoshimoto; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara; lee hagey; Alan F Hofmann
Chemical synthesis of (22E)-3 alpha,6 beta,7 beta-trihydroxy-5 beta-chol-22-en-24-oic acid and its taurine and glycine conjugates: a major bile acid in the rat.
Journal of lipid research 2004;45(3):567-73.
2003: Takashi Iida; Keisuke Shiraishi; Shoujiro Ogawa; Junichi Goto; Toshio Nambara
An improved method for the capillary gas chromatographic derivatization of polyhydroxylated steroids having tert-hydroxyl groups.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2003;19(9):1317-21.
2003: Takashi Iida; Keisuke Shiraishi; Shoujiro Ogawa; Takaaki Goto; Nariyasu Mano; Junichi Goto; Toshio Nambara
Functionalization of unactivated carbons in 3alpha,6- and 3alpha,24-dihydroxy-5beta-cholane derivatives by dimethyldioxirane.
Lipids 2003;38(3):281-7.
2002: Takashi Iida; Masahiro Hikosaka; Genta Kakiyama; Keisuke Shiraishi; Claudio D Schteingart; lee hagey; Huong-Thu Ton-Nu; Alan F Hofmann; Nariyasu Mano; Junichi Goto; Toshio Nambara
Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3alpha,7alpha,16- and 3alpha,7alpha,15-trihydroxy-5beta-cholan-24-oic acids.
Chemical & pharmaceutical bulletin 2002;50(10):1327-34.
2001: Takashi Iida; M Hikosaka; Junichi Goto; Toshio Nambara
Capillary gas chromatographic behaviour of tert.-hydroxylated steroids by trialkylsilylation.
Journal of chromatography. A 2001;937(1-2):97-105.
2001: T Sasaki; R Nakamori; T Yamaguchi; Y Kasuga; Takashi Iida; Toshio Nambara
The application of dimethyldioxirane for the selective oxidation of polyfunctional steroids.
Chemistry and physics of lipids 2001;109(2):135-43.
2000: T Sasaki; Takashi Iida; Toshio Nambara
High-performance ion-pair chromatographic behaviour of conjugated bile acids with di-n-butylamine acetate.
Journal of chromatography. A 2000;888(1-2):93-102.