Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Johan Auwerx

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Disorders

Obesity

Concepts & Ideas

Molecular Sequence Data

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Yu Jiujiu; Auwerx Johan
The role of sirtuins in the control of metabolic homeostasis.
Thomas Charles; Gioiello Antimo; Noriega Lilia; Strehle Axelle; Oury Julien; Rizzo Giovanni; Macchiarulo Antonio; Yamamoto Hiroyasu; Mataki Chikage; Pruzanski Mark; Pellicciari Roberto; Auwerx Johan; Schoonjans Kristina
TGR5-mediated bile acid sensing controls glucose homeostasis.
Cantó Carles; Auwerx Johan
Caloric restriction, SIRT1 and longevity.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Johan Auwerx (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Yu Jiujiu; Auwerx Johan
The role of sirtuins in the control of metabolic homeostasis.
Annals of the New York Academy of Sciences 2009;1173 Suppl 1():E10-9.
2009: Thomas Charles; Gioiello Antimo; Noriega Lilia; Strehle Axelle; Oury Julien; Rizzo Giovanni; Macchiarulo Antonio; Yamamoto Hiroyasu; Mataki Chikage; Pruzanski Mark; Pellicciari Roberto; Auwerx Johan; Schoonjans Kristina
TGR5-mediated bile acid sensing controls glucose homeostasis.
Cell metabolism 2009;10(3):167-77.
2009: Cantó Carles; Auwerx Johan
Caloric restriction, SIRT1 and longevity.
Trends in endocrinology and metabolism: TEM 2009;20(7):325-31.
2009: Patti Mary-Elizabeth; Houten Sander M; Bianco Antonio C; Bernier Raquel; Larsen P Reed; Holst Jens J; Badman Michael K; Maratos-Flier Eleftheria; Mun Edward C; Pihlajamaki Jussi; Auwerx Johan; Goldfine Allison B
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism.
Obesity (Silver Spring, Md.) 2009;17(9):1671-7.
2009: Koutnikova Hana; Laakso Markku; Lu Lu; Combe Roy; Paananen Jussi; Kuulasmaa Teemu; Kuusisto Johanna; Häring Hans-Ulrich; Hansen Torben; Pedersen Oluf; Smith Ulf; Hanefeld Markolf; Williams Robert W; Auwerx Johan
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
PLoS genetics 2009;5(8):e1000591.
2009: Cybulski Nadine; Polak Pazit; Auwerx Johan; Rüegg Markus A; Hall Michael N
mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(24):9902-7.
2009: Cantó Carles; Auwerx Johan
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.
Current opinion in lipidology 2009;20(2):98-105.
2009: Cantó Carles; Gerhart-Hines Zachary; Feige Jerome N; Lagouge Marie; Noriega Lilia; Milne Jill C; Elliott Peter J; Puigserver Pere; Auwerx Johan
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.
Nature 2009;458(7241):1056-60.
2009: Heikkinen Sami; Argmann Carmen; Feige Jérôme N; Koutnikova Hana; Champy Marie-France; Dali-Youcef Nassim; Schadt Eric E; Laakso Markku; Auwerx Johan
The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.
Cell metabolism 2009;9(1):88-98.
2009: Terrand Jérome; Bruban Véronique; Zhou Li; Gong Wanfeng; El Asmar Zeina; May Petra; Zurhove Kai; Haffner Philipp; Philippe Claude; Woldt Estelle; Matz Rachel L; Gracia Céline; Metzger Daniel; Auwerx Johan; Herz Joachim; Boucher Philippe
LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling.
The Journal of biological chemistry 2009;284(1):381-8.
2008: Polak Pazit; Cybulski Nadine; Feige Jerome N; Auwerx Johan; Rüegg Markus A; Hall Michael N
Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
Cell metabolism 2008;8(5):399-410.
2008: Feige Jérôme N; Lagouge Marie; Canto Carles; Strehle Axelle; Houten Sander M; Milne Jill C; Lambert Philip D; Mataki Chikage; Elliott Peter J; Auwerx Johan
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.
Cell metabolism 2008;8(5):347-58.
2008: Coste Agnès; Louet Jean-Francois; Lagouge Marie; Lerin Carles; Antal Maria Cristina; Meziane Hamid; Schoonjans Kristina; Puigserver Pere; O'Malley Bert W; Auwerx Johan
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):17187-92.
2008: Feige Jérôme N; Lagouge Marie; Auwerx Johan
Dietary manipulation of mouse metabolism.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2008;Chapter 29():Unit 29B.5.
2008: Macchiarulo Antonio; Gioiello Antimo; Thomas Charles; Massarotti Alberto; Nuti Roberto; Rosatelli Emiliano; Sabbatini Paola; Schoonjans Kristina; Auwerx Johan; Pellicciari Roberto
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5.
Journal of chemical information and modeling 2008;48(9):1792-801.
2008: Thomas Charles; Pellicciari Roberto; Pruzanski Mark; Auwerx Johan; Schoonjans Kristina
Targeting bile-acid signalling for metabolic diseases.
Nature reviews. Drug discovery 2008;7(8):678-93.
2008: Mandillo Silvia; Tucci Valter; Hölter Sabine M; Meziane Hamid; Banchaabouchi Mumna Al; Kallnik Magdalena; Lad Heena V; Nolan Patrick M; Ouagazzal Abdel-Mouttalib; Coghill Emma L; Gale Karin; Golini Elisabetta; Jacquot Sylvie; Krezel Wojtek; Parker Andy; Riet Fabrice; Schneider Ilka; Marazziti Daniela; Auwerx Johan; Brown Steve D M; Chambon Pierre; Rosenthal Nadia; Tocchini-Valentini Glauco; Wurst Wolfgang
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study.
Physiological genomics 2008;34(3):243-55.
2008: Duggavathi Rajesha; Volle David H; Mataki Chikage; Antal Maria C; Messaddeq Nadia; Auwerx Johan; Murphy Bruce D; Schoonjans Kristina
Liver receptor homolog 1 is essential for ovulation.
Genes & development 2008;22(14):1871-6.
2008: Cantó Carles; Auwerx Johan
Glucose restriction: longevity SIRTainly, but without building muscle?
Developmental cell 2008;14(5):642-4.
2008: Champy Marie-France; Selloum Mohammed; Zeitler Valérie; Caradec Claudia; Jung Barbara; Rousseau Stéphane; Pouilly Laurent; Sorg Tania; Auwerx Johan
Genetic background determines metabolic phenotypes in the mouse.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(5):318-31.
2008: Coste Agnès; Lagane Céline; Filipe Cédric; Authier Hélène; Galès Amandine; Bernad José; Douin-Echinard Victorine; Lepert Jean-Claude; Balard Patricia; Linas Marie-Denise; Arnal Jean-François; Auwerx Johan; Pipy Bernard
IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2(-/-) mice via peroxisome proliferator-activated receptor-gamma activation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4939-47.
2008: Sato Hiroyuki; Macchiarulo Antonio; Thomas Charles; Gioiello Antimo; Une Mizuho; Hofmann Alan F; Saladin Régis; Schoonjans Kristina; Pellicciari Roberto; Auwerx Johan
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
Journal of medicinal chemistry 2008;51(6):1831-41.
2008: Thomas Charles; Auwerx Johan; Schoonjans Kristina
Bile acids and the membrane bile acid receptor TGR5--connecting nutrition and metabolism.
Thyroid : official journal of the American Thyroid Association 2008;18(2):167-74.
2008: Delayre-Orthez Carine; Becker Julien; Auwerx Johan; Frossard Nelly; Pons Françoise
Suppression of allergen-induced airway inflammation and immune response by the peroxisome proliferator-activated receptor-alpha agonist fenofibrate.
European journal of pharmacology 2008;581(1-2):177-84.
2007: Bai Péter; Houten Sander M; Huber Aline; Schreiber Valérie; Watanabe Mitsuhiro; Kiss Borbála; de Murcia Gilbert; Auwerx Johan; Ménissier-de Murcia Josiane
Poly(ADP-ribose) polymerase-2 [corrected] controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/peroxisome proliferator-activated receptor-gamma [corrected] heterodimer.
The Journal of biological chemistry 2007;282(52):37738-46.
2007: Mataki Chikage; Magnier Benjamin C; Houten Sander M; Annicotte Jean-Sébastien; Argmann Carmen; Thomas Charles; Overmars Henk; Kulik Wim; Metzger Daniel; Auwerx Johan; Schoonjans Kristina
Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.
Molecular and cellular biology 2007;27(23):8330-9.
2007: Feige Jerome N; Auwerx Johan
DisSIRTing on LXR and cholesterol metabolism.
Cell metabolism 2007;6(5):343-5.
2007: Sato Hiroyuki; Genet Cédric; Strehle Axelle; Thomas Charles; Lobstein Annelise; Wagner Alain; Mioskowski Charles; Auwerx Johan; Saladin Régis
Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea.
Biochemical and biophysical research communications 2007;362(4):793-8.
2007: Antal Cristina; Teletin Marius; Wendling Olivia; Dgheem Mounzer; Auwerx Johan; Mark Manuel
Tissue collection for systematic phenotyping in the mouse.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2007;Chapter 29():Unit 29A.4.
2007: Gofflot Françoise; Chartoire Nathalie; Vasseur Laurent; Heikkinen Sami; Dembele Doulaye; Le Merrer Julie; Auwerx Johan
Systematic gene expression mapping clusters nuclear receptors according to their function in the brain.
Cell 2007;131(2):405-18.
2007: Rasouri Soumya; Lagouge Marie; Auwerx Johan
[SIRT1/PGC-1: a neuroprotective axis?]
Médecine sciences : M/S 2007;23(10):840-4.
2007: Pellicciari Roberto; Sato Hiroyuki; Gioiello Antimo; Costantino Gabriele; Macchiarulo Antonio; Sadeghpour Bahman M; Giorgi Gianluca; Schoonjans Kristina; Auwerx Johan
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.
Journal of medicinal chemistry 2007;50(18):4265-8.
2007: Coste Agnes; Dubuquoy Laurent; Barnouin Romain; Annicotte Jean-Sebastien; Magnier Benjamin; Notti Mario; Corazza Nadia; Antal Maria Cristina; Metzger Daniel; Desreumaux Pierre; Brunner Thomas; Auwerx Johan; Schoonjans Kristina
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):13098-103.
2007: Heikkinen Sami; Auwerx Johan; Argmann Carmen A
PPARgamma in human and mouse physiology.
Biochimica et biophysica acta 2007;1771(8):999-1013.
2007: Yamamoto Hiroyasu; Schoonjans Kristina; Auwerx Johan
Sirtuin functions in health and disease.
Molecular endocrinology (Baltimore, Md.) 2007;21(8):1745-55.
2007: Dali-Youcef Nassim; Mataki Chikage; Coste Agnès; Messaddeq Nadia; Giroud Sylvain; Blanc Stéphane; Koehl Christian; Champy Marie-France; Chambon Pierre; Fajas Lluis; Metzger Daniel; Schoonjans Kristina; Auwerx Johan
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10703-8.
2007: Feige Jérôme N; Auwerx Johan
Transcriptional coregulators in the control of energy homeostasis.
Trends in cell biology 2007;17(6):292-301.
2007: Berry Antoine; Balard Patricia; Coste Agnès; Olagnier David; Lagane Céline; Authier Hélène; Benoit-Vical Françoise; Lepert Jean-Claude; Séguéla Jean-Paul; Magnaval Jean-François; Chambon Pierre; Metzger Daniel; Desvergne Béatrice; Wahli Walter; Auwerx Johan; Pipy Bernard
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.
European journal of immunology 2007;37(6):1642-52.
2007: Houten Sander M; Volle David H; Cummins Carolyn L; Mangelsdorf David J; Auwerx Johan
In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue.
Molecular endocrinology (Baltimore, Md.) 2007;21(6):1312-23.
2007: Mark Manuel; Teletin Marius; Antal Cristina; Wendling Olivia; Auwerx Johan; Heikkinen Sami; Khetchoumian Konstantin; Argmann Carmen A; Dgheem Mounzer
Histopathology in mouse metabolic investigations.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2007;Chapter 29():Unit 29B.4.
2007: Dubrac Sandrine; Stoitzner Patrizia; Pirkebner Daniela; Elentner Andreas; Schoonjans Kristina; Auwerx Johan; Saeland Sem; Hengster Paul; Fritsch Peter; Romani Nikolaus; Schmuth Matthias
Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4362-72.
2007: Volle David H; Duggavathi Rajesha; Magnier Benjamin C; Houten Sander M; Cummins Carolyn L; Lobaccaro Jean-Marc A; Verhoeven Guido; Schoonjans Kristina; Auwerx Johan
The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.
Genes & development 2007;21(3):303-15.
2007: Heikkinen Sami; Argmann Carmen A; Champy Marie-France; Auwerx Johan
Evaluation of glucose homeostasis.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2007;Chapter 29():Unit 29B.3.
2007: Grarup Niels; Andersen Mette K; Andreasen Camilla H; Albrechtsen Anders; Borch-Johnsen Knut; Jørgensen Torben; Auwerx Johan; Schmitz Ole; Hansen Torben; Pedersen Oluf
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.
The Journal of clinical endocrinology and metabolism 2007;92(1):363-6.
2007: Dali-Youcef Nassim; Lagouge Marie; Froelich Sébastien; Koehl Christian; Schoonjans Kristina; Auwerx Johan
Sirtuins: the 'magnificent seven', function, metabolism and longevity.
Annals of medicine 2007;39(5):335-45.
2007: Boucher Philippe; Li Wei-Ping; Matz Rachel L; Takayama Yoshiharu; Auwerx Johan; Anderson Richard G W; Herz Joachim
LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.
PloS one 2007;2(5):e448.
2006: Michalik Liliane; Auwerx Johan; Berger Joel P; Chatterjee V Krishna; Glass Christopher K; Gonzalez Frank J; Grimaldi Paul A; Kadowaki Takashi; Lazar Mitchell A; O'Rahilly Stephen; Palmer Colin N A; Plutzky Jorge; Reddy Janardan K; Spiegelman Bruce M; Staels Bart; Wahli Walter
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.
Pharmacological reviews 2006;58(4):726-41.
2006: Lagouge Marie; Argmann Carmen; Gerhart-Hines Zachary; Meziane Hamid; Lerin Carles; Daussin Frederic; Messadeq Nadia; Milne Jill; Lambert Philip; Elliott Peter; Geny Bernard; Laakso Markku; Puigserver Pere; Auwerx Johan
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Cell 2006;127(6):1109-22.
2006: Louet Jean-Francois; Coste Agnès; Amazit Larbi; Tannour-Louet Mounia; Wu Ray-Chang; Tsai Sophia Y; Tsai Ming-Jer; Auwerx Johan; O'Malley Bert W
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17868-73.
2006: Argmann Carmen; Auwerx Johan
Insulin secretion: SIRT4 gets in on the act.
Cell 2006;126(5):837-9.
2006: Argmann Carmen A; Houten Sander M; Champy Marie-France; Auwerx Johan
Lipid and bile acid analysis.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 29():Unit 29B.2.
2006: Argmann Carmen A; Auwerx Johan
Collection of blood and plasma from the mouse.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 29():Unit 29A.3.
2006: Peltola Paula; Pihlajamäki Jussi; Koutnikova Hana; Ruotsalainen Eija; Salmenniemi Urpu; Vauhkonen Ilkka; Kainulainen Sakari; Gylling Helena; Miettinen Tatu A; Auwerx Johan; Laakso Markku
Visceral obesity is associated with high levels of serum squalene.
Obesity (Silver Spring, Md.) 2006;14(7):1155-63.
2006: Loichot Cécile; Jesel Laurence; Tesse Angela; Tabernero Antonia; Schoonjans Kristina; Roul Gérard; Carpusca Irina; Auwerx Johan; Andriantsitohaina Ramaroson
Deletion of peroxisome proliferator-activated receptor-alpha induces an alteration of cardiac functions.
American journal of physiology. Heart and circulatory physiology 2006;291(1):H161-6.
2006: Coste Agnès; Antal Maria Cristina; Chan Susan; Kastner Philippe; Mark Manuel; O'Malley Bert W; Auwerx Johan
Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.
The EMBO journal 2006;25(11):2453-64.
2006: Houten Sander M; Watanabe Mitsuhiro; Auwerx Johan
Endocrine functions of bile acids.
The EMBO journal 2006;25(7):1419-25.
2006: Rodriguez Angelina; Durán Angeles; Selloum Mohammed; Champy Marie-France; Diez-Guerra Francisco J; Flores Juana María; Serrano Manuel; Auwerx Johan; Diaz-Meco María T; Moscat Jorge
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.
Cell metabolism 2006;3(3):211-22.
2006: Argmann Carmen A; Champy Marie-France; Auwerx Johan
Evaluation of energy homeostasis.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 29():Unit 29B.1.
2006: Argmann Carmen A; Auwerx Johan
Minimizing variation due to genotype and environment.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 29():Unit 29A.2.
2006: Argmann Carmen A; Dierich Andree; Auwerx Johan
Uses of forward and reverse genetics in mice to study gene function.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2006;Chapter 29():Unit 29A.1.
2006: Watanabe Mitsuhiro; Houten Sander M; Mataki Chikage; Christoffolete Marcelo A; Kim Brian W; Sato Hiroyuki; Messaddeq Nadia; Harney John W; Ezaki Osamu; Kodama Tatsuhiko; Schoonjans Kristina; Bianco Antonio C; Auwerx Johan
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.
Nature 2006;439(7075):484-9.
2006: Auwerx Johan
Improving metabolism by increasing energy expenditure.
Nature medicine 2006;12(1):44-5; discussion 45.
2005: Morozova Svetlana; Suc-Royer Isabelle; Auwerx Johan
[Cholesterol metabolism modulators in future drug therapy for atherosclerosis]
Médecine sciences : M/S 2005;21 Spec No():53-8.
2005: Argmann Carmen A; Chambon Pierre; Auwerx Johan
Mouse phenogenomics: the fast track to "systems metabolism".
Cell metabolism 2005;2(6):349-60.
2005: Debril M-B; Dubuquoy L; Feige J-N; Wahli W; Desvergne B; Auwerx J; Gelman L
Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity.
Journal of molecular endocrinology 2005;35(3):503-17.
2005: Meirhaeghe Aline; Tanck Michael W T; Fajas Lluis; Janot Caroline; Helbecque Nicole; Cottel Dominique; Auwerx Johan; Amouyel Philippe; Dallongeville Jean
Study of a new PPARgamma2 promoter polymorphism and haplotype analysis in a French population.
Molecular genetics and metabolism 2005;85(2):140-8.
2005: Rousseaux Christel; Lefebvre Bruno; Dubuquoy Laurent; Lefebvre Philippe; Romano Olivier; Auwerx Johan; Metzger Daniel; Wahli Walter; Desvergne Béatrice; Naccari Gian Carlo; Chavatte Philippe; Farce Amaury; Bulois Philippe; Cortot Antoine; Colombel Jean Frédéric; Desreumaux Pierre
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
The Journal of experimental medicine 2005;201(8):1205-15.
2005: Dharancy Sébastien; Malapel Mathilde; Perlemuter Gabriel; Roskams Tania; Cheng Yang; Dubuquoy Laurent; Podevin Philippe; Conti Filoména; Canva Valérie; Philippe David; Gambiez Luc; Mathurin Philippe; Paris Jean-Claude; Schoonjans Kristina; Calmus Yvon; Pol Stanislas; Auwerx Johan; Desreumaux Pierre
Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.
Gastroenterology 2005;128(2):334-42.
2005: Schoonjans Kristina; Dubuquoy Laurent; Mebis Joseph; Fayard Elisabeth; Wendling Olivia; Haby Céline; Geboes Karel; Auwerx Johan
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2058-62.
2005: Argmann C A; Cock T-A; Auwerx J
Peroxisome proliferator-activated receptor gamma: the more the merrier?
European journal of clinical investigation 2005;35(2):82-92; discussion 80.
2005: Delayre-Orthez Carine; Becker Julien; Guenon Isabelle; Lagente Vincent; Auwerx Johan; Frossard Nelly; Pons Françoise
PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse.
Respiratory research 2005;6():91.
2004: Knouff Chris; Auwerx Johan
Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology.
Endocrine reviews 2004;25(6):899-918.
2004: Champy Marie-France; Selloum Mohammed; Piard Laetitia; Zeitler Valerie; Caradec Claudia; Chambon Pierre; Auwerx Johan
Mouse functional genomics requires standardization of mouse handling and housing conditions.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(10):768-83.
2004: Houten Sander M; Auwerx Johan
PGC-1alpha: turbocharging mitochondria.
Cell 2004;119(1):5-7.
2004: Cock Terrie-Anne; Back Jonathan; Elefteriou Florent; Karsenty Gérard; Kastner Philippe; Chan Susan; Auwerx Johan
Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen.
EMBO reports 2004;5(10):1007-12.
2004: Um Sung Hee; Frigerio Francesca; Watanabe Mitsuhiro; Picard Frédéric; Joaquin Manel; Sticker Melanie; Fumagalli Stefano; Allegrini Peter R; Kozma Sara C; Auwerx Johan; Thomas George
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Nature 2004;431(7005):200-5.
2004: Botrugno Oronza A; Fayard Elisabeth; Annicotte Jean-Sébastien; Haby Céline; Brennan Thomas; Wendling Olivia; Tanaka Toshiya; Kodama Tatsuhiko; Thomas Winston; Auwerx Johan; Schoonjans Kristina
Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation.
Molecular cell 2004;15(4):499-509.
2004: Morozova Svetlana; Suc-Royer Isabelle; Auwerx Johan
[Cholesterol metabolism modulators and the future of atherosclerosis therapy]
Médecine sciences : M/S 2004;20(6-7):685-90.
2004: Watanabe Mitsuhiro; Houten Sander M; Wang Li; Moschetta Antonio; Mangelsdorf David J; Heyman Richard A; Moore David D; Auwerx Johan
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.
The Journal of clinical investigation 2004;113(10):1408-18.
2004: Fayard Elisabeth; Auwerx Johan; Schoonjans Kristina
LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis.
Trends in cell biology 2004;14(5):250-60.
2004: Fajas Lluis; Annicotte Jean-Sébastien; Miard Stéphanie; Sarruf David; Watanabe Mitsuhiro; Auwerx Johan
Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice.
The Journal of clinical investigation 2004;113(9):1288-95.
2004: Dalen Knut Tomas; Schoonjans Kristina; Ulven Stine M; Weedon-Fekjaer Mina Susanne; Bentzen Trine Gjesti; Koutnikova Hana; Auwerx Johan; Nebb Hilde I
Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma.
Diabetes 2004;53(5):1243-52.
2004: Schmuth Matthias; Haqq Christopher M; Cairns William J; Holder Julie C; Dorsam Sheri; Chang Sandra; Lau Peggy; Fowler Ashley J; Chuang Gary; Moser Arthur H; Brown Barbara E; Mao-Qiang Man; Uchida Yoshikazu; Schoonjans Kristina; Auwerx Johan; Chambon P; Willson Timothy M; Elias Peter M; Feingold Kenneth R
Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes.
The Journal of investigative dermatology 2004;122(4):971-83.
2004: Annicotte Jean-Sébastien; Schoonjans Kristina; Auwerx Johan
Expression of the liver X receptor alpha and beta in embryonic and adult mice.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2004;277(2):312-6.
2004: Debril Marie-Bernard; Gelman Laurent; Fayard Elisabeth; Annicotte Jean-Sébastien; Rocchi Stéphane; Auwerx Johan
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.
The Journal of biological chemistry 2004;279(16):16677-86.
2004: Mascrez Bénédicte; Ghyselinck Norbert B; Watanabe Mitsuhiro; Annicotte Jean-Sébastien; Chambon Pierre; Auwerx Johan; Mark Manuel
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
EMBO reports 2004;5(3):285-90.
2004: Cock Terrie-Anne; Houten Sander M; Auwerx Johan
Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm.
EMBO reports 2004;5(2):142-7.
2004: Houten Sander M; Auwerx Johan
The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts.
Annals of medicine 2004;36(7):482-91.
2003: Tanaka Toshiya; Yamamoto Joji; Iwasaki Satoshi; Asaba Hiroshi; Hamura Hiroki; Ikeda Yukio; Watanabe Mitsuhiro; Magoori Kenta; Ioka Ryoichi X; Tachibana Keisuke; Watanabe Yuichiro; Uchiyama Yasutoshi; Sumi Koichi; Iguchi Haruhisa; Ito Sadayoshi; Doi Takefumi; Hamakubo Takao; Naito Makoto; Auwerx Johan; Yanagisawa Masashi; Kodama Tatsuhiko; Sakai Juro
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15924-9.
2003: Auwerx Johan; Drouin Jacques; Laudet Vincent
Récepteurs à la Provençale. EMBO workshop on the biology of nuclear receptors.
EMBO reports 2003;4(12):1122-6.
2003: Cock Terrie-Anne; Auwerx Johan
Leptin: cutting the fat off the bone.
Lancet 2003;362(9395):1572-4.
2003: Koutnikova Hana; Cock Terrie-Anne; Watanabe Mitsuhiro; Houten Sander M; Champy Marie-France; Dierich Andreé; Auwerx Johan
Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14457-62.
2003: Banfi Cristina; Auwerx Johan; Poma Federica; Tremoli Elena; Mussoni Luciana
Induction of plasminogen activator inhibitor I by the PPARalpha ligand, Wy-14,643, is dependent on ERK1/2 signaling pathway.
Thrombosis and haemostasis 2003;90(4):611-9.
2003: Annicotte Jean-Sébastien; Fayard Elisabeth; Swift Galvin H; Selander Lars; Edlund Helena; Tanaka Toshiya; Kodama Tatsuhiko; Schoonjans Kristina; Auwerx Johan
Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development.
Molecular and cellular biology 2003;23(19):6713-24.
2003: Fayard Elisabeth; Schoonjans Kristina; Annicotte Jean-Sébastien; Auwerx Johan
Liver receptor homolog 1 controls the expression of carboxyl ester lipase.
The Journal of biological chemistry 2003;278(37):35725-31.
2003: Fajas Lluis; Miard Stephanie; Briggs Michael R; Auwerx Johan
Selective cyclo-oxygenase-2 inhibitors impair adipocyte differentiation through inhibition of the clonal expansion phase.
Journal of lipid research 2003;44(9):1652-9.
2003: Woerly Gaetane; Honda Kohei; Loyens Marc; Papin Jean-Paul; Auwerx Johan; Staels Bart; Capron Monique; Dombrowicz David
Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation.
The Journal of experimental medicine 2003;198(3):411-21.
2003: Fajas Lluis; Egler Viviane; Reiter Raphael; Miard Stéphanie; Lefebvre Anne-Marie; Auwerx Johan
PPARgamma controls cell proliferation and apoptosis in an RB-dependent manner.
Oncogene 2003;22(27):4186-93.
2003: Francis Gordon A; Annicotte Jean-Sébastien; Auwerx Johan
PPAR-alpha effects on the heart and other vascular tissues.
American journal of physiology. Heart and circulatory physiology 2003;285(1):H1-9.
2003: Dubuquoy Laurent; Jansson Emmelie A; Deeb Samir; Rakotobe Sabine; Karoui Mehdi; Colombel Jean-Frédéric; Auwerx Johan; Pettersson Sven; Desreumaux Pierre
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis.
Gastroenterology 2003;124(5):1265-76.
2003: Francis Gordon A; Annicotte Jean-Sébastien; Auwerx Johan
PPAR agonists in the treatment of atherosclerosis.
Current opinion in pharmacology 2003;3(2):186-91.
2003: Meirhaeghe Aline; Fajas Lluis; Gouilleux Fabrice; Cottel Dominique; Helbecque Nicole; Auwerx Johan; Amouyel Philippe
A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French population.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(2):289-94.
2003: Auwerx Johan; Cock Terrie-Ann; Knouff Chris
PPAR-gamma: a thrifty transcription factor.
Nuclear receptor signaling 2003;1():e006.
2003: Koutnikova Hana; Fayard Elisabeth; Lehmann Jürgen; Auwerx Johan
Serial analysis of gene expression and gene trapping to identify nuclear receptor target genes.
Methods in enzymology 2003;364():299-322.
2003: Francis Gordon A; Fayard Elisabeth; Picard Frédéric; Auwerx Johan
Nuclear receptors and the control of metabolism.
Annual review of physiology 2003;65():261-311.
2002: Picard Frédéric; Géhin Martine; Annicotte Jean- Sébastien; Rocchi Stéphane; Champy Marie-France; O'Malley Bert W; Chambon Pierre; Auwerx Johan
SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
Cell 2002;111(7):931-41.
2002: Schmuth Matthias; Schoonjans Kristina; Yu Qian-Chun; Fluhr Joachim W; Crumrine Debra; Hachem Jean-Pierre; Lau Peggy; Auwerx Johan; Elias Peter M; Feingold Kenneth R
Role of peroxisome proliferator-activated receptor alpha in epidermal development in utero.
The Journal of investigative dermatology 2002;119(6):1298-303.
2002: Fajas Lluis; Egler Viviane; Reiter Raphael; Hansen Jacob; Kristiansen Karsten; Debril Marie-Bernard; Miard Stéphanie; Auwerx Johan
The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation.
Developmental cell 2002;3(6):903-10.
2002: Schoonjans Kristina; Annicotte Jean-Sebastien; Huby Thierry; Botrugno Oronza A; Fayard Elisabeth; Ueda Yukihiko; Chapman John; Auwerx Johan
Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I.
EMBO reports 2002;3(12):1181-7.
2002: Fournier Thierry; Pavan Laetitia; Tarrade Anne; Schoonjans Kristina; Auwerx Johan; Rochette-Egly Cecile; Evain-Brion Daniele
The role of PPAR-gamma/RXR-alpha heterodimers in the regulation of human trophoblast invasion.
Annals of the New York Academy of Sciences 2002;973():26-30.
2002: Picard Frédéric; Wanatabe Mitsuhiro; Schoonjans Kristina; Lydon John; O'Malley Bert W; Auwerx Johan
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15644-8.
2002: Dubuquoy Laurent; Dharancy Sébastien; Nutten Sophie; Pettersson Sven; Auwerx Johan; Desreumaux Pierre
Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases.
Lancet 2002;360(9343):1410-8.
2002: Francis Gordon A; Annicotte Jean-Sebastien; Auwerx Johan
Liver X receptors: Xcreting Xol to combat atherosclerosis.
Trends in molecular medicine 2002;8(10):455-8.
2002: Brendel Carole; Schoonjans Kristina; Botrugno Oronza A; Treuter Eckardt; Auwerx Johan
The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity.
Molecular endocrinology (Baltimore, Md.) 2002;16(9):2065-76.
2002: Schoonjans Kristina; Auwerx Johan
A sharper image of SHP.
Nature medicine 2002;8(8):789-91.
2002: Eligini Sonia; Brambilla Marta; Banfi Cristina; Camera Marina; Sironi Luigi; Barbieri Silvia Stella; Auwerx Johan; Tremoli Elena; Colli Susanna
Oxidized phospholipids inhibit cyclooxygenase-2 in human macrophages via nuclear factor-kappaB/IkappaB- and ERK2-dependent mechanisms.
Cardiovascular research 2002;55(2):406-15.
2002: Fajas Lluis; Landsberg Rebecca L; Huss-Garcia Yolande; Sardet Claude; Lees Jacqueline A; Auwerx Johan
E2Fs regulate adipocyte differentiation.
Developmental cell 2002;3(1):39-49.
2002: Koutnikova Hana; Auwerx Johan
PPARgamma, an X-ceptor for Xs.
Annals of the New York Academy of Sciences 2002;967():28-33.
2002: Brendel Carole; Gelman Laurent; Auwerx Johan
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism.
Molecular endocrinology (Baltimore, Md.) 2002;16(6):1367-77.
2002: Ylitalo Kati; Nuotio Ilpo; Viikari Jorma; Auwerx Johan; Vidal Hubert; Taskinen Marja-Riitta
C3, hormone-sensitive lipase, and peroxisome proliferator-activated receptor gamma expression in adipose tissue of familial combined hyperlipidemia patients.
Metabolism: clinical and experimental 2002;51(5):664-70.
2002: Tabernero Antonia; Schoonjans Kristina; Jesel Laurence; Carpusca Irina; Auwerx Johan; Andriantsitohaina Ramaroson
Activation of the peroxisome proliferator-activated receptor alpha protects against myocardial ischaemic injury and improves endothelial vasodilatation.
BMC pharmacology 2002;2():10.
2002: Auwerx Johan
Nuclear receptors. I. PPAR gamma in the gastrointestinal tract: gain or pain?
American journal of physiology. Gastrointestinal and liver physiology 2002;282(4):G581-5.
2002: Sheu Mary Y; Fowler Ashley J; Kao Jack; Schmuth Matthias; Schoonjans Kristina; Auwerx Johan; Fluhr Joachim W; Man Mao-Qiang; Elias Peter M; Feingold Kenneth R
Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models.
The Journal of investigative dermatology 2002;118(1):94-101.
2002: Tanaka Toshiya; Takeno Tetsu; Watanabe Yuichiro; Uchiyama Yasutoshi; Murakami Takeshi; Yamashita Hisahiko; Suzuki Akifumi; Aoi Rie; Iwanari Hiroko; Jiang Shu-Ying; Naito Makoto; Tachibana Keisuke; Doi Takefumi; Shulman Andrew I; Mangelsdorf David J; Reiter Raphael; Auwerx Johan; Hamakubo Takao; Kodama Tatsuhiko
The generation of monoclonal antibodies against human peroxisome proliferator-activated receptors (PPARs).
Journal of atherosclerosis and thrombosis 2002;9(5):233-42.
2002: Picard Frédéric; Auwerx Johan
PPAR(gamma) and glucose homeostasis.
Annual review of nutrition 2002;22():167-97.
2001: Koutnikova H; Auwerx J
Regulation of adipocyte differentiation.
Annals of medicine 2001;33(8):556-61.
2001: Annicotte J S; Schoonjans K; Haby C; Auwerx J
An E-box in pGL3 reporter vectors precludes their use for the study of sterol regulatory element-binding proteins.
BioTechniques 2001;31(5):993-4, 996.
2001: Rocchi S; Picard F; Vamecq J; Gelman L; Potier N; Zeyer D; Dubuquoy L; Bac P; Champy M F; Plunket K D; Leesnitzer L M; Blanchard S G; Desreumaux P; Moras D; Renaud J P; Auwerx J
A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity.
Molecular cell 2001;8(4):737-47.
2001: Tarrade A; Schoonjans K; Pavan L; Auwerx J; Rochette-Egly C; Evain-Brion D; Fournier T
PPARgamma/RXRalpha heterodimers control human trophoblast invasion.
The Journal of clinical endocrinology and metabolism 2001;86(10):5017-24.
2001: Tarrade A; Schoonjans K; Guibourdenche J; Bidart J M; Vidaud M; Auwerx J; Rochette-Egly C; Evain-Brion D
PPAR gamma/RXR alpha heterodimers are involved in human CG beta synthesis and human trophoblast differentiation.
Endocrinology 2001;142(10):4504-14.
2001: Akiyama T E; Nicol C J; Fievet C; Staels B; Ward J M; Auwerx J; Lee S S; Gonzalez F J; Peters J M
Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines.
The Journal of biological chemistry 2001;276(42):39088-93.
2001: Fajas L; Debril M B; Auwerx J
Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis.
Journal of molecular endocrinology 2001;27(1):1-9.
2001: Rieusset J; Chambrier C; Bouzakri K; Dusserre E; Auwerx J; Riou J P; Laville M; Vidal H
The expression of the p85alpha subunit of phosphatidylinositol 3-kinase is induced by activation of the peroxisome proliferator-activated receptor gamma in human adipocytes.
Diabetologia 2001;44(5):544-54.
2001: Desreumaux P; Dubuquoy L; Nutten S; Peuchmaur M; Englaro W; Schoonjans K; Derijard B; Desvergne B; Wahli W; Chambon P; Leibowitz M D; Colombel J F; Auwerx J
Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.
The Journal of experimental medicine 2001;193(7):827-38.
2001: Fayard E; Schoonjans K; Auwerx J
Xol INXS: role of the liver X and the farnesol X receptors.
Current opinion in lipidology 2001;12(2):113-20.
2001: Fajas L; Debril M B; Auwerx J
PPAR gamma: an essential role in metabolic control.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2001;11(1):64-9.
2001: Claudel T; Leibowitz M D; Fiévet C; Tailleux A; Wagner B; Repa J J; Torpier G; Lobaccaro J M; Paterniti J R; Mangelsdorf D J; Heyman R A; Auwerx J
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2610-5.
2001: Davies P J; Berry S A; Shipley G L; Eckel R H; Hennuyer N; Crombie D L; Ogilvie K M; Peinado-Onsurbe J; Fievet C; Leibowitz M D; Heyman R A; Auwerx J
Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity.
Molecular pharmacology 2001;59(2):170-6.
2001: Debril M B; Renaud J P; Fajas L; Auwerx J
The pleiotropic functions of peroxisome proliferator-activated receptor gamma.
Journal of molecular medicine (Berlin, Germany) 2001;79(1):30-47.
2000: Rocchi S; Auwerx J
Peroxisome proliferator-activated receptor gamma, the ultimate liaison between fat and transcription.
The British journal of nutrition 2000;84 Suppl 2():S223-7.
2000: Schoonjans K; Brendel C; Mangelsdorf D; Auwerx J
Sterols and gene expression: control of affluence.
Biochimica et biophysica acta 2000;1529(1-3):114-25.
2000: Schoonjans K; Gelman L; Haby C; Briggs M; Auwerx J
Induction of LPL gene expression by sterols is mediated by a sterol regulatory element and is independent of the presence of multiple E boxes.
Journal of molecular biology 2000;304(3):323-34.
2000: Binnert C; Koistinen H A; Martin G; Andreelli F; Ebeling P; Koivisto V A; Laville M; Auwerx J; Vidal H
Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans.
American journal of physiology. Endocrinology and metabolism 2000;279(5):E1072-9.
2000: Kömüves L G; Hanley K; Lefebvre A M; Man M Q; Ng D C; Bikle D D; Williams M L; Elias P M; Auwerx J; Feingold K R
Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo.
The Journal of investigative dermatology 2000;115(3):353-60.
2000: Dubuquoy L; Bourdon C; Peuchmaur M; Leibowitz M D; Nutten S; Colombel J F; Auwerx J; Desreumaux P
[Peroxisome proliferator-activated receptor (PPAR) gamma: a new target for the treatment of inflammatory bowel disease]
Gastroentérologie clinique et biologique 2000;24(8-9):719-24.
2000: Pihlajamäki J; Miettinen R; Valve R; Karjalainen L; Mykkänen L; Kuusisto J; Deeb S; Auwerx J; Laakso M
The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia.
Atherosclerosis 2000;151(2):567-74.
2000: Martin G; Nemoto M; Gelman L; Geffroy S; Najib J; Fruchart J C; Roevens P; de Martinville B; Deeb S; Auwerx J
The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression.
Genomics 2000;66(3):296-304.
2000: Leibowitz M D; Fiévet C; Hennuyer N; Peinado-Onsurbe J; Duez H; Bergera J; Cullinan C A; Sparrow C P; Baffic J; Berger G D; Santini C; Marquis R W; Tolman R L; Smith R G; Moller D E; Auwerx J
Activation of PPARdelta alters lipid metabolism in db/db mice.
FEBS letters 2000;473(3):333-6.
2000: Tobin K A; Steineger H H; Alberti S; Spydevold O; Auwerx J; Gustafsson J A; Nebb H I
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.
Molecular endocrinology (Baltimore, Md.) 2000;14(5):741-52.
2000: Meirhaeghe A; Martin G; Nemoto M; Deeb S; Cottel D; Auwerx J; Amouyel P; Helbecque N
Intronic polymorphism in the fatty acid transport protein 1 gene is associated with increased plasma triglyceride levels in a French population.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(5):1330-4.
2000: Martin G; Poirier H; Hennuyer N; Crombie D; Fruchart J C; Heyman R A; Besnard P; Auwerx J
Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target.
The Journal of biological chemistry 2000;275(17):12612-8.
2000: Hanley K; Kömüves L G; Ng D C; Schoonjans K; He S S; Lau P; Bikle D D; Williams M L; Elias P M; Auwerx J; Feingold K R
Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha.
The Journal of biological chemistry 2000;275(15):11484-91.
2000: Schoonjans K; Auwerx J
Thiazolidinediones: an update.
Lancet 2000;355(9208):1008-10.
1999: Rieusset J; Auwerx J; Vidal H
Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes.
Biochemical and biophysical research communications 1999;265(1):265-71.
1999: Valve R; Sivenius K; Miettinen R; Pihlajamäki J; Rissanen A; Deeb S S; Auwerx J; Uusitupa M; Laakso M
Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese women.
The Journal of clinical endocrinology and metabolism 1999;84(10):3708-12.
1999: Lefebvre M; Paulweber B; Fajas L; Woods J; McCrary C; Colombel J F; Najib J; Fruchart J C; Datz C; Vidal H; Desreumaux P; Auwerx J
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.
The Journal of endocrinology 1999;162(3):331-40.
1999: Fajas L; Schoonjans K; Gelman L; Kim J B; Najib J; Martin G; Fruchart J C; Briggs M; Spiegelman B M; Auwerx J
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism.
Molecular and cellular biology 1999;19(8):5495-503.
1999: Desreumaux P; Ernst O; Geboes K; Gambiez L; Berrebi D; Müller-Alouf H; Hafraoui S; Emilie D; Ectors N; Peuchmaur M; Cortot A; Capron M; Auwerx J; Colombel J F
Inflammatory alterations in mesenteric adipose tissue in Crohn's disease.
Gastroenterology 1999;117(1):73-81.
1999: Schoonjans K; Peinado-Onsurbe J; Fruchart J C; Tailleux A; Fiévet C; Auwerx J
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase.
FEBS letters 1999;452(3):160-4.
1999: Rieusset J; Andreelli F; Auboeuf D; Roques M; Vallier P; Riou J P; Auwerx J; Laville M; Vidal H
Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor-gamma in human adipocytes.
Diabetes 1999;48(4):699-705.
1999: Gelman L; Zhou G; Fajas L; Raspé E; Fruchart J C; Auwerx J
p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.
The Journal of biological chemistry 1999;274(12):7681-8.
1999: Saladin R; Fajas L; Dana S; Halvorsen Y D; Auwerx J; Briggs M
Differential regulation of peroxisome proliferator activated receptor gamma1 (PPARgamma1) and PPARgamma2 messenger RNA expression in the early stages of adipogenesis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(1):43-8.
1998: Lefebvre A M; Chen I; Desreumaux P; Najib J; Fruchart J C; Geboes K; Briggs M; Heyman R; Auwerx J
Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice.
Nature medicine 1998;4(9):1053-7.
1998: Ricote M; Huang J; Fajas L; Li A; Welch J; Najib J; Witztum J L; Auwerx J; Palinski W; Glass C K
Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7614-9.
1998: Martin G; Schoonjans K; Staels B; Auwerx J
PPARgamma activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes.
Atherosclerosis 1998;137 Suppl():S75-80.
1998: Staels B; Auwerx J
Regulation of apo A-I gene expression by fibrates.
Atherosclerosis 1998;137 Suppl():S19-23.
1998: Lefebvre A M; Laville M; Vega N; Riou J P; van Gaal L; Auwerx J; Vidal H
Depot-specific differences in adipose tissue gene expression in lean and obese subjects.
Diabetes 1998;47(1):98-103.
1997: Martin G; Schoonjans K; Lefebvre A M; Staels B; Auwerx J
Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators.
The Journal of biological chemistry 1997;272(45):28210-7.
1997: Peters J M; Hennuyer N; Staels B; Fruchart J C; Fievet C; Gonzalez F J; Auwerx J
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice.
The Journal of biological chemistry 1997;272(43):27307-12.
1997: Lefebvre A M; Peinado-Onsurbe J; Leitersdorf I; Briggs M R; Paterniti J R; Fruchart J C; Fievet C; Auwerx J; Staels B
Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(9):1756-64.
1997: Hallakou S; Doaré L; Foufelle F; Kergoat M; Guerre-Millo M; Berthault M F; Dugail I; Morin J; Auwerx J; Ferré P
Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.
Diabetes 1997;46(9):1393-9.
1997: Auboeuf D; Rieusset J; Fajas L; Vallier P; Frering V; Riou J P; Staels B; Auwerx J; Laville M; Vidal H
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients.
Diabetes 1997;46(8):1319-27.
1997: Fajas L; Auboeuf D; Raspé E; Schoonjans K; Lefebvre A M; Saladin R; Najib J; Laville M; Fruchart J C; Deeb S; Vidal-Puig A; Flier J; Briggs M R; Staels B; Vidal H; Auwerx J
The organization, promoter analysis, and expression of the human PPARgamma gene.
The Journal of biological chemistry 1997;272(30):18779-89.
1996: Schoonjans K; Peinado-Onsurbe J; Lefebvre A M; Heyman R A; Briggs M; Deeb S; Staels B; Auwerx J
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.
The EMBO journal 1996;15(19):5336-48.
1996: Sabugal R; Robert M Q; Julve J; Auwerx J; Llobera M; Peinado-Onsurbe J
Hepatic regeneration induces changes in lipoprotein lipase activity in several tissues and its re-expression in the liver.
The Biochemical journal 1996;318 ( Pt 2)():597-602.
1996: Bossu J P; Chartier F L; Fruchart J C; Auwerx J; Staels B; Laine B
Two regulatory elements of similar structure and placed in tandem account for the repressive activity of the first intron of the human apolipoprotein A-II gene.
The Biochemical journal 1996;318 ( Pt 2)():547-53.
1996: De Vos P; Lefebvre A M; Miller S G; Guerre-Millo M; Wong K; Saladin R; Hamann L G; Staels B; Briggs M R; Auwerx J
Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.
The Journal of clinical investigation 1996;98(4):1004-9.
1996: Auwerx J; Schoonjans K; Fruchart J C; Staels B
Transcriptional control of triglyceride metabolism: fibrates and fatty acids change the expression of the LPL and apo C-III genes by activating the nuclear receptor PPAR.
Atherosclerosis 1996;124 Suppl():S29-37.
1996: Vidal H; Auboeuf D; De Vos P; Staels B; Riou J P; Auwerx J; Laville M
The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue.
The Journal of clinical investigation 1996;98(2):251-5.
1996: Saladin R; Vu-Dac N; Fruchart J C; Auwerx J; Staels B
Transcriptional induction of rat liver apolipoprotein A-I gene expression by glucocorticoids requires the glucocorticoid receptor and a labile cell-specific protein.
European journal of biochemistry / FEBS 1996;239(2):451-9.
1996: Vu-Dac N; Schoonjans K; Kosykh V; Dallongeville J; Heyman R A; Staels B; Auwerx J
Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.
Molecular and cellular biology 1996;16(7):3350-60.
1996: Staels B; Martin G; Martinez M; Albert C; Peinado-Onsurbe J; Saladin R; Hum D W; Reina M; Vilaro S; Auwerx J
Expression and regulation of the lipoprotein lipase gene in human adrenal cortex.
The Journal of biological chemistry 1996;271(29):17425-32.
1996: Casaroli-Marano R P; Peinado-Onsurbe J; Reina M; Staels B; Auwerx J; Vilaró S
Lipoprotein lipase in highly vascularized structures of the eye.
Journal of lipid research 1996;37(5):1037-44.
1996: Miller S G; De Vos P; Guerre-Millo M; Wong K; Hermann T; Staels B; Briggs M R; Auwerx J
The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5507-11.
1996: Buscà R; Martínez M; Vilella E; Pognonec P; Deeb S; Auwerx J; Reina M; Vilaró S
The mutation Gly142-->Glu in human lipoprotein lipase produces a missorted protein that is diverted to lysosomes.
The Journal of biological chemistry 1996;271(4):2139-46.
1995: Saladin R; De Vos P; Guerre-Millo M; Leturque A; Girard J; Staels B; Auwerx J
Transient increase in obese gene expression after food intake or insulin administration.
Nature 1995;377(6549):527-9.
1995: Schoonjans K; Watanabe M; Suzuki H; Mahfoudi A; Krey G; Wahli W; Grimaldi P; Staels B; Yamamoto T; Auwerx J
Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter.
The Journal of biological chemistry 1995;270(33):19269-76.
1995: Vu-Dac N; Schoonjans K; Kosykh V; Dallongeville J; Fruchart J C; Staels B; Auwerx J
Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor.
The Journal of clinical investigation 1995;96(2):741-50.
1995: De Vos P; Saladin R; Auwerx J; Staels B
Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake.
The Journal of biological chemistry 1995;270(27):15958-61.
1995: Buscà R; Peinado J; Vilella E; Auwerx J; Deeb S S; Vilaró S; Reina M
The mutant Asn291-->Ser human lipoprotein lipase is associated with reduced catalytic activity and does not influence binding to heparin.
FEBS letters 1995;367(3):257-62.
1995: Buscá R; Pujana M A; Pognonec P; Auwerx J; Deeb S S; Reina M; Vilaró S
Absence of N-glycosylation at asparagine 43 in human lipoprotein lipase induces its accumulation in the rough endoplasmic reticulum and alters this cellular compartment.
Journal of lipid research 1995;36(5):939-51.
1995: Staels B; Vu-Dac N; Kosykh V A; Saladin R; Fruchart J C; Dallongeville J; Auwerx J
Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates.
The Journal of clinical investigation 1995;95(2):705-12.
1994: Vu-Dac N; Schoonjans K; Laine B; Fruchart J C; Auwerx J; Staels B
Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.
The Journal of biological chemistry 1994;269(49):31012-8.
1994: Jarvik G P; Austin M A; Fabsitz R R; Auwerx J; Reed T; Christian J C; Deeb S
Genetic influences on age-related change in total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels: longitudinal apolipoprotein E genotype effects.
Genetic epidemiology 1994;11(4):375-84.
1993: Schoonjans K; Staels B; Grimaldi P; Auwerx J
Acyl-CoA synthetase mRNA expression is controlled by fibric-acid derivatives, feeding and liver proliferation.
European journal of biochemistry / FEBS 1993;216(2):615-22.
1993: Schoonjans K; Staels B; Devos P; Szpirer J; Szpirer C; Deeb S; Verhoeven G; Auwerx J
Developmental extinction of liver lipoprotein lipase mRNA expression might be regulated by an NF-1-like site.
FEBS letters 1993;329(1-2):89-95.
1993: van Dijck P; Schoonjans K; Sassone-Corsi P; Auwerx J; Verhoeven G
A Fos-Jun element in the first intron of an alpha 2u-globulin gene.
Molecular and cellular biochemistry 1993;125(2):127-36.
1993: Peinado-Onsurbe J; Staels B; Vanderschueren D; Bouillon R; Auwerx J
Effects of sex steroids on hepatic and lipoprotein lipase activity and mRNA in the rat.
Hormone research 1993;40(5-6):184-8.
1992: Auwerx J; Sassone-Corsi P
AP-1 (Fos-Jun) regulation by IP-1: effect of signal transduction pathways and cell growth.
Oncogene 1992;7(11):2271-80.
1992: Jansen H; van Tol A; Auwerx J; Skretting G; Staels B
Opposite regulation of hepatic lipase and lecithin: cholesterol acyltransferase by glucocorticoids in rats.
Biochimica et biophysica acta 1992;1128(2-3):181-5.
1992: Peinado-Onsurbe J; Staels B; Deeb S; Auwerx J
Lipoprotein lipase expression in undifferentiated hepatoma cells is regulated by progesterone and protein kinase A.
Biochemistry 1992;31(41):10121-8.
1992: Staels B; Auwerx J
Perturbation of developmental gene expression in rat liver by fibric acid derivatives: lipoprotein lipase and alpha-fetoprotein as models.
Development (Cambridge, England) 1992;115(4):1035-43.
1992: Descheemaeker K A; Wyns S; Nelles L; Auwerx J; Ny T; Collen D
Interaction of AP-1-, AP-2-, and Sp1-like proteins with two distinct sites in the upstream regulatory region of the plasminogen activator inhibitor-1 gene mediates the phorbol 12-myristate 13-acetate response.
The Journal of biological chemistry 1992;267(21):15086-91.
1992: Peinado-Onsurbe J; Staels B; Deeb S; Ramirez I; Llobera M; Auwerx J
Neonatal extinction of liver lipoprotein lipase expression.
Biochimica et biophysica acta 1992;1131(3):281-6.
1992: Auwerx J; Bouillon R; Kesteloot H
Relation between 25-hydroxyvitamin D3, apolipoprotein A-I, and high density lipoprotein cholesterol.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(6):671-4.
1992: Staels B; van Tol A; Skretting G; Auwerx J
Lecithin:cholesterol acyltransferase gene expression is regulated in a tissue-selective manner by fibrates.
Journal of lipid research 1992;33(5):727-35.
1992: Staels B; van Tol A; Andreu T; Auwerx J
Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(3):286-94.
1992: Staels B; Peinado-Onsurbe J; Auwerx J
Down-regulation of hepatic lipase gene expression and activity by fenofibrate.
Biochimica et biophysica acta 1992;1123(2):227-30.
1992: Auwerx J; Staels B; Van Vaeck F; Ceuppens J L
Changes in IgG Fc receptor expression induced by phorbol 12-myristate 13-acetate treatment of THP-1 monocytic leukemia cells.
Leukemia research 1992;16(3):317-27.
1992: Auwerx J; Leroy P; Schoonjans K
Lipoprotein lipase: recent contributions from molecular biology.
Critical reviews in clinical laboratory sciences 1992;29(3-4):243-68.
1992: Auwerx J
Regulation of gene expression by fatty acids and fibric acid derivatives: an integrative role for peroxisome proliferator activated receptors. The Belgian Endocrine Society Lecture 1992.
Hormone research 1992;38(5-6):269-77.
1991: Staels B; van Tol A; Jansen H; Auwerx J
The effects of probucol on lipoprotein metabolism in the rat.
Biochimica et biophysica acta 1991;1085(1):131-5.
1991: Staels B; van Tol A; Chan L; Verhoeven G; Auwerx J
Variable effects of different corticosteroids on plasma lipids, apolipoproteins, and hepatic apolipoprotein mRNA levels in rats.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(3):760-9.
1991: Van Ranst M; Norga K; Masure S; Proost P; Vandekerckhove F; Auwerx J; Van Damme J; Opdenakker G
The cytokine-protease connection: identification of a 96-kD THP-1 gelatinase and regulation by interleukin-1 and cytokine inducers.
Cytokine 1991;3(3):231-9.
1990: Staels B; Van Tol A; Chan L; Will H; Verhoeven G; Auwerx J
Alterations in thyroid status modulate apolipoprotein, hepatic triglyceride lipase, and low density lipoprotein receptor in rats.
Endocrinology 1990;127(3):1144-52.
1990: Staels B; Jansen H; van Tol A; Stahnke G; Will H; Verhoeven G; Auwerx J
Development, food intake, and ethinylestradiol influence hepatic triglyceride lipase and LDL-receptor mRNA levels in rats.
Journal of lipid research 1990;31(7):1211-8.
1990: Staels B; van Tol A; Verhoeven G; Auwerx J
Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific manner.
Endocrinology 1990;126(4):2153-63.
1990: Auwerx J H; Babirak S P; Hokanson J E; Stahnke G; Will H; Deeb S S; Brunzell J D
Coexistence of abnormalities of hepatic lipase and lipoprotein lipase in a large family.
American journal of human genetics 1990;46(3):470-7.
1990: Auwerx J; Staels B; Sassone-Corsi P
Coupled and uncoupled induction of fos and jun transcription by different second messengers in cells of hematopoietic origin.
Nucleic acids research 1990;18(2):221-8.
1989: Auwerx J H; Chait A; Wolfbauer G; Deeb S S
Loss of copper-zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin.
Blood 1989;74(5):1807-10.
1989: Auwerx J H; Babirak S P; Fujimoto W Y; Iverius P H; Brunzell J D
Defective enzyme protein in lipoprotein lipase deficiency.
European journal of clinical investigation 1989;19(5):433-7.
1989: Staels B; Auwerx J; Chan L; van Tol A; Rosseneu M; Verhoeven G
Influence of development, estrogens, and food intake on apolipoprotein A-I, A-II, and E mRNA in rat liver and intestine.
Journal of lipid research 1989;30(8):1137-45.
1989: Auwerx J H; Chait A; Wolfbauer G; Deeb S S
Involvement of second messengers in regulation of the low-density lipoprotein receptor gene.
Molecular and cellular biology 1989;9(6):2298-302.
1989: Auwerx J H; Deeb S; Brunzell J D; Wolfbauer G; Chait A
Lipoprotein lipase gene expression in THP-1 cells.
Biochemistry 1989;28(11):4563-7.
1989: Auwerx J H; Marzetta C A; Hokanson J E; Brunzell J D
Large buoyant LDL-like particles in hepatic lipase deficiency.
Arteriosclerosis (Dallas, Tex.) 1989;9(3):319-25.
1989: Auwerx J H; Chait A; Deeb S S
Regulation of the low density lipoprotein receptor and hydroxymethylglutaryl coenzyme A reductase genes by protein kinase C and a putative negative regulatory protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(4):1133-7.
1988: Auwerx J H; Deeb S; Brunzell J D; Peng R; Chait A
Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines.
Biochemistry 1988;27(8):2651-5.
1988: Auwerx J; Dequeker J; Bouillon R; Geusens P; Nijs J
Mineral metabolism and bone mass at peripheral and axial skeleton in diabetes mellitus.
Diabetes 1988;37(1):8-12.
1988: Auwerx J; Bouillon R; Collen D; Geboers J
Tissue-type plasminogen activator antigen and plasminogen activator inhibitor in diabetes mellitus.
Arteriosclerosis (Dallas, Tex.) 1988;8(1):68-72.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Johan Auwerx

Research Profile (preview)

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Disorders

Concepts & Ideas

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Johan Auwerx (preview)

All Publications