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Hajime Iizuka

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Hidetoshi Takahashi; Michinari Takahashi; Akira Takei; Hitomi Tsuji; Akemi Ishida-Yamamoto; Katsuya Koike; Satoshi Nakamura; Hikaru Shibaki; Yoshio Hashimoto; Masaru Honma; Hajime Iizuka
Japanese patients with psoriasis and atopic dermatitis show distinct personality profiles.
Masako Minami-Hori; Hidetoshi Takahashi; Hitomi Tsuji; Kazuomi Hanada; Hajime Iizuka
Optic neuritis in a psoriatic arthritis patient treated by infliximab.
Masaru Honma; Shin Iinuma; Akemi Ishida-Yamamoto; Masako Minami-Hori; Hidetoshi Takahashi; Mizue Fujii; Hajime Iizuka
Podoplanin expression is inversely correlated with granular layer/filaggrin formation in psoriatic epidermis.

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2013: Hidetoshi Takahashi; Michinari Takahashi; Akira Takei; Hitomi Tsuji; Akemi Ishida-Yamamoto; Katsuya Koike; Satoshi Nakamura; Hikaru Shibaki; Yoshio Hashimoto; Masaru Honma; Hajime Iizuka
Japanese patients with psoriasis and atopic dermatitis show distinct personality profiles.
The Journal of dermatology 2013;40(5):370-3.
2013: Masako Minami-Hori; Hidetoshi Takahashi; Hitomi Tsuji; Kazuomi Hanada; Hajime Iizuka
Optic neuritis in a psoriatic arthritis patient treated by infliximab.
The Journal of dermatology 2013;40(4):298-9.
2013: Masaru Honma; Shin Iinuma; Akemi Ishida-Yamamoto; Masako Minami-Hori; Hidetoshi Takahashi; Mizue Fujii; Hajime Iizuka
Podoplanin expression is inversely correlated with granular layer/filaggrin formation in psoriatic epidermis.
The Journal of dermatology 2013;40(4):296-7.
2013: Mizue Fujii; Masaru Honma; Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
Intercellular contact augments epidermal growth factor receptor (EGFR) and signal transducer and activator of transcription 3 (STAT3)-activation which increases podoplanin-expression in order to promote squamous cell carcinoma motility.
Cellular signalling 2013;25(4):760-5.
2013: Hidetoshi Takahashi; Hitomi Tsuji; Masaru Honma; Akemi Ishida-Yamamoto; Hajime Iizuka
Increased plasma resistin and decreased omentin levels in Japanese patients with psoriasis.
Archives of dermatological research 2013;305(2):113-6.
2013: Hidetoshi Takahashi; Hitomi Tsuji; Akemi Ishida-Yamamoto; Hajime Iizuka
Plasma trough levels of adalimumab and infliximab in terms of clinical efficacy during the treatment of psoriasis.
The Journal of dermatology 2013;40(1):39-42.
2012: Yasuhiro Ito; Yasushi Ohishi; Jiro Uehara; Akemi I Yamamoto; Satomi Igawa; Hajime Iizuka
Prognostic indicators in 35 patients with extramammary Paget's disease.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2012;38(12):1938-44.
2012: Masaru Honma; Shigetsuna Komatsu; Masako Minami-Hori; Hitomi Tsuji; Hajime Iizuka
Olanzapine-induced limb edema simulating episodic angioedema with eosinophilia.
The Journal of dermatology 2012;39(12):1105-6.
2012: Hidetoshi Takahashi; Hitomi Tsuji; Masaru Honma; Akemi Ishida-Yamamoto; Hikaru Shibaki; Hajime Iizuka
Patients with psoriasis and atopic dermatitis show distinct anxiety profiles.
The Journal of dermatology 2012;39(11):955-6.
2012: Hidetoshi Takahashi; Hitomi Tsuji; Masaru Honma; Akemi Ishida-Yamamoto; Hajime Iizuka
Femoral head osteonecrosis after long-term topical corticosteroid treatment in a psoriasis patient.
The Journal of dermatology 2012;39(10):887-8.
2012: Takashi Shibuya; Hidetoshi Takahashi; Ichiro Takahashi; Akemi Ishida-Yamamoto; Takafumi Kamiya; Shigetsuna Komatsu; Shunpei Fukuda; Takashi Hashimoto; Masaru Honma; Hajime Iizuka
Mucous membrane pemphigoid accompanied by ovarian cancer: a case with autoantibodies solely against γ(2) -subunit of laminin-332.
The Journal of dermatology 2012;39(10):882-4.
2012: Takanori Kaneko; Mari Kishibe; Vera B Morhenn; Masamoto Murakami; Maria Brattsand; Akemi Ishida-Yamamoto; Hajime Iizuka
Over-expression of kallikrein related peptidases in palmoplantar pustulosis.
Journal of dermatological science 2012;67(1):73-6.
2012: Kazuhiro Kaneta; Mari Kishibe; Masaru Honma; Hajime Iizuka
Perilipin and adipophilin expression regulated by Rho-kinase during differentiation of hamster sebocyte.
The Journal of dermatology 2012;39(7):641-4.
2012: Hidetoshi Takahashi; Ryuji Asano; Yoshinori Nakae; Susumu Nakajima; Isao Sakata; Hajime Iizuka
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma.
Journal of dermatological science 2012;66(3):221-4.
2012: Mari Kishibe; Tatsuhide Tanaka; Yoshio Bando; Hajime Iizuka; Akemi Ishida-Yamamoto; Shigetaka Yoshida
Kallikrein-related peptidase 8-dependent skin wound healing is associated with upregulation of kallikrein-related peptidase 6 and PAR2.
The Journal of investigative dermatology 2012;132(6):1717-24.
2012: Masaru Honma; Satomi Igawa; Shigetsuna Komatsu; Masamoto Murakami; Hajime Iizuka
Rapidly progressive systemic sclerosis associated with breast carcinoma: report of a case with anti-RNA polymerase III antibody.
The Journal of dermatology 2012;39(6):574-6.
2012: Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Yoichi Fukami; Masaru Honma; Hajime Iizuka
Successful combination therapy with dapsone and cyclosporine for erythema elevatum diutinum with unusual appearance.
The Journal of dermatology 2012;39(5):486-7.
2012: Satoshi Nakamura; Kaoru Nishi; Hidetoshi Takahashi; Keiko Takeda; Yoshio Hashimoto; Toshihiro Mizumoto; Hajime Iizuka
Favorable clinical response by pre-prandial administration of low-dose ciclosporin to severe adult atopic dermatitis.
The Journal of dermatological treatment 2012;23(2):112-5.
2012: Hidetoshi Takahashi; Hajime Iizuka
Psoriasis and metabolic syndrome.
The Journal of dermatology 2012;39(3):212-8.
2012: Masaru Honma; Masako Minami-Hori; Hidetoshi Takahashi; Hajime Iizuka
Podoplanin expression in wound and hyperproliferative psoriatic epidermis: regulation by TGF-β and STAT-3 activating cytokines, IFN-γ, IL-6, and IL-22.
Journal of dermatological science 2012;65(2):134-40.
2012: Akemi Ishida-Yamamoto; Mari Kishibe; masamoto murakami; Hidetoshi Takahashi; Masaru Honma; Hajime Iizuka
Lamellar granule secretion starts before the establishment of tight junction barrier for paracellular tracers in mammalian epidermis.
PloS one 2012;7(2):e31641.
2011: Hidetoshi Takahashi; Hajime Iizuka; Fumio Kaneko; Hidemi Nakagawa; Koichiro Nakamura
Analysis of psoriasis patients registered with the Japanese Society for Psoriasis Research from 2002-2008.
The Journal of dermatology 2011;38(12):1125-9.
2011: M Fujii; Masaru Honma; Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
The nuclear factor kappa B p50 subunit and cortactin as markers to distinguish between keratoacanthoma and well-differentiated squamous cell carcinoma.
Clinical and experimental dermatology 2011;36(7):788-92.
2011: masamoto murakami; Eva Hagforsen; Akemi Ishida-Yamamoto; Vera Morhenn; Hajime Iizuka
Patients with palmoplantar pustulosis have increased IL-17 and IL-22 levels both in the lesion and serum.
Experimental dermatology 2011;20(10):845-7.
2011: Masaru Honma; Shigetsuna Komatsu; Ichiro Takahashi; Hajime Iizuka
Armor-like calcinosis in systemic lupus erythematosus.
The Journal of dermatology 2011;38(10):1021-4.
2011: M Minami-Hori; Hidetoshi Takahashi; I Takahashi; Masaru Honma; Akemi Ishida-Yamamoto; Y Ito; Hajime Iizuka
Adult orbital xanthogranulomatous disease: adult-onset xanthogranuloma of periorbital location.
Clinical and experimental dermatology 2011;36(6):628-31.
2011: Yasuhiro Ito; Mizue Fujii; Takashi Shibuya; Jiro Uehara; Katsuhiko Sato; Hajime Iizuka
Granulocyte colony stimulating factor-producing squamous cell carcinoma of the skin.
The Journal of dermatology 2011;38(5):515-7.
2011: M Fujii; Masaru Honma; S Iinuma; K Kaneta; S Komatsu; K Sato; Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Hajime Iizuka
Recalcitrant facial pemphigus vulgaris: correlation of skin lesions with the ratio of antidesmoglein antibodies 1 and 3.
Clinical and experimental dermatology 2011;36(3):284-7.
2011: Mizue Fujii; Jiro Uehara; Masaru Honma; Yasuhiro Ito; Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Hajime Iizuka
Primary cutaneous γδ-T-cell lymphoma treated with low-dose methotrexate and narrowband ultraviolet B irradiation: report of a case with testicular involvement.
The Journal of dermatology 2011;38(4):368-72.
2011: Masaru Honma; Mizue Fujii; Shin Iinuma; Shigetsuna Komatsu; Akemi Ishida-Yamamoto; Hajime Iizuka
Erythema annulare centrifugum simulating erythema gyratum repens.
The Journal of dermatology 2011;38(2):192-3.
2011: Satomi Igawa; Mari Kishibe; masamoto murakami; Masaru Honma; Hidetoshi Takahashi; Hajime Iizuka; Akemi Ishida-Yamamoto
Tight junctions in the stratum corneum explain spatial differences in corneodesmosome degradation.
Experimental dermatology 2011;20(1):53-7.
2011: M Honma; N Kato; M Hashimoto; H Takahashi; A Ishida-Yamamoto; Hajime Iizuka
Subungual keratoacanthoma: analysis of cell proliferation and copy number variation of oncogenes compared with periungual squamous cell carcinoma.
Clinical and experimental dermatology 2011;36(1):57-62.
2010: Hitomi Tsuji; Takashi Wada; masamoto murakami; Takayuki Kashiwagi; Yasuhiro Ito; Akemi Ishida-Yamamoto; Junko Jimbo; Motohiro Shindo; Kazuya Sato; Yutaka Kohgo; Hajime Iizuka
Two cases of mycosis fungoides treated by reduced-intensity cord blood transplantation.
The Journal of dermatology 2010;37(12):1040-5.
2010: Yasuhiro Ito; Haruki Doi; Hitomi Tsuji; Akemi Ishida-Yamamto; Hajime Iizuka
Malignant melanoma of the breast: N-isopropyl-p-(123) I-iodoamphetamine single photon emission computed tomography ((123) I-IMP SPECT) is useful for the detection of metastasis.
The Journal of dermatology 2010;37(9):849-51.
2010: Hidetoshi Takahashi; Masaru Honma; Akemi Ishida-Yamamoto; Hajime Iizuka
Adiponectin and leptin modulate cell proliferation and cytokine secretion of normal human keratinocytes and T lymphocytes.
Journal of dermatological science 2010;59(2):143-5.
2010: masamoto murakami; Takaaki Ohtake; Yoshimune Horibe; Akemi Ishida-Yamamoto; Vera B Morhenn; Richard L Gallo; Hajime Iizuka
Acrosyringium is the main site of the vesicle/pustule formation in palmoplantar pustulosis.
The Journal of investigative dermatology 2010;130(8):2010-6.
2010: Hidetoshi Takahashi; Kazuhiro Kaneta; Masaru Honma; Akemi Ishida-Yamamoto; Tomonori Ashida; Yutaka Kohgo; Yoshinobu Ohsaki; Hajime Iizuka
Sarcoidosis during infliximab therapy for Crohn's disease.
The Journal of dermatology 2010;37(5):471-4.
2010: Jiro Uehara; Yasuhiro Ito; Ichiro Takahashi; Masaru Honma; Akemi Ishida-Yamamoto; Shinobu Matsuo; Hajime Iizuka
Sequential acral lentiginous melanomas of the foot.
Case reports in dermatology 2010;2(3):201-6.
2010: Masaru Honma; Shinichi Tobisawa; Shin Iinuma; Takashi Shibuya; Shigetsuna Komatsu; Ichiro Takahashi; Akemi Ishida-Yamamoto; Hajime Iizuka
Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7.
Dermatology (Basel, Switzerland) 2010;221(4):306-8.
2009: Hidetoshi Takahashi; Ichiro Takahashi; Hitomi Tsuji; Masaki Ibe; Motoshi Kinouchi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Shinobu Matsuo; Noritaka Ohkuma; Akira Ohkawara; Hajime Iizuka
Analysis of psoriatic patients registered in Asahikawa Medical College Hospital from 1983 to 2007.
The Journal of dermatology 2009;36(12):632-7.
2009: Mari Kishibe; Hiroyuki Sakai; Hajime Iizuka
Acute edema/cutaneous distention syndrome associated with refeeding in a patient with anorexia nervosa.
Archives of dermatology 2009;145(10):1202-3.
2009: Hidetoshi Takahashi; Hitomi Tsuji; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Hajime Iizuka
CELL PROLIFERATION AND CYTOKINE INDUCTION BY TNF-alpha OF PSORIATIC KERATINOCYTES ARE NOT DIFFERENT FROM NORMAL KERATINOCYTES IN VITRO.
Indian journal of dermatology 2009;54(3):237-9.
2009: Hiroya Kobayashi; Makoto Azumi; Yuka Kimura; Keisuke Sato; Naoko Aoki; Shoji Kimura; Masaru Honma; Hajime Iizuka; Masatoshi Tateno; Esteban Celis
Focal adhesion kinase as an immunotherapeutic target.
Cancer immunology, immunotherapy : CII 2009;58(6):931-40.
2009: Hidetoshi Takahashi; Hitomi Tsuji; Ichiro Takahashi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Hajime Iizuka
Prevalence of obesity/adiposity in Japanese psoriasis patients: adiposity is correlated with the severity of psoriasis.
Journal of dermatological science 2009;54(1):61-3.
2009: Masako Minami-Hori; Akemi Ishida-Yamamoto; Hajime Iizuka
Cornoid lamellae associated with follicular infundibulum and acrosyringium in porokeratosis.
The Journal of dermatology 2009;36(3):125-30.
2008: Masaru Honma; Makoto Hashimoto; Takeshi Iwasaki; Shin Iinuma; Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Hajime Iizuka
Primary cutaneous anaplastic large cell lymphoma successfully treated with local thermotherapy using pocket hand warmers.
The Journal of dermatology 2008;35(11):748-50.
2008: Hidetoshi Takahashi; H Tsuji; I Takahashi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Hajime Iizuka
Plasma adiponectin and leptin levels in Japanese patients with psoriasis.
The British journal of dermatology 2008;159(5):1207-8.
2008: Sawa Otsubo; Masaru Honma; Kazuhiro Asano; Hidetoshi Takahashi; Hajime Iizuka
A novel germ-line mutation of PTCH1 gene in a Japanese family of nevoid basal cell carcinoma syndrome: are the palmoplantar pits associated with true basal cell carcinoma?
Journal of dermatological science 2008;51(2):144-6.
2008: Masaru Honma; Yasushi Ohishi; Jiro Uehara; Masaki Ibe; Motoshi Kinouchi; Akemi Ishida-Yamamoto; Hajime Iizuka
A novel PTCH1 mutation in a patient of nevoid basal cell carcinoma syndrome.
Journal of dermatological science 2008;50(1):73-5.
2008: Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Susumu Nakajima; Isao Sakata; Hajime Iizuka
ATX-S10(Na)-photodynamic therapy inhibits cytokine secretion and proliferation of lymphocytes.
Journal of dermatological science 2008;49(2):174-7.
2007: masamoto murakami; Takashi Wada; Takayuki Kashiwagi; Akemi Ishida-Yamamoto; Hajime Iizuka
Nodular malignant melanoma with Spitz nevus-like pathological features finally confirmed by the pathological feature of the sentinel lymph node.
The Journal of dermatology 2007;34(12):821-8.
2007: Akemi Ishida-Yamamoto; Mari Kishibe; Hidetoshi Takahashi; Hajime Iizuka
Rab11 is associated with epidermal lamellar granules.
The Journal of investigative dermatology 2007;127(9):2166-70.
2007: Hidetoshi Takahashi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Toshifumi Ashida; Yutaka Kohgo; Hajime Iizuka
Psoriasiform and pustular eruption induced by infliximab.
The Journal of dermatology 2007;34(7):468-72.
2007: Hidetoshi Takahashi; Naritsuna Komatsu; Masaki Ibe; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Cystatin A suppresses ultraviolet B-induced apoptosis of keratinocytes.
Journal of dermatological science 2007;46(3):179-87.
2006: Hidetoshi Takahashi; Shigetsuna Komatsu; Masaki Ibe; Akemi Ishida-Yamamoto; Susumu Nakajima; Isao Sakata; Hajime Iizuka
ATX-S10(Na)-PDT shows more potent effect on collagen metabolism of human normal and scleroderma dermal fibroblasts than ALA-PDT.
Archives of dermatological research 2006;298(6):257-63.
2005: Hidetoshi Takahashi; Susumu Nakajima; Isao Sakata; Akemi Ishida-Yamamoto; Hajime Iizuka
ATX-S10(Na)-photodynamic therapy is less carcinogenic for mouse skin compared with ultraviolet B irradiation.
The British journal of dermatology 2005;153(6):1182-6.
2005: Hidetoshi Takahashi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Hajime Iizuka
Roxithromycin suppresses involucrin expression by modulation of activator protein-1 and nuclear factor-kappaB activities of keratinocytes.
Journal of dermatological science 2005;39(3):175-82.
2005: Atsushi Sekiguchi; Takayuki Kashiwagi; Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Yoshio Hashimoto; Hiroshi Kimura; Mikiko Tohyama; Koji Hashimoto; Hajime Iizuka
Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.
The Journal of dermatology 2005;32(4):278-81.
2005: Hidetoshi Takahashi; Susumu Nakajima; Isao Sakata; Akemi Ishida-Yamamoto; Hajime Iizuka
Photodynamic therapy using a novel photosensitizer, ATX-S10(Na): comparative effect with 5-aminolevulinic acid on squamous cell carcinoma cell line, SCC15, ultraviolet B-induced skin tumor, and phorbol ester-induced hyperproliferative skin.
Archives of dermatological research 2005;296(10):496-502.
2005: Hiroyuki Sakai; Yoichi Fukami; Masaki Ibe; Yoshio Hashimoto; Hajime Iizuka
A case of a fixed drug eruption presenting with a butterfly rash-like exanthem in a patient with Sjögren's syndrome.
International journal of dermatology 2005;44(3):260-2.
2005: Akemi Ishida-Yamamoto; Céline Deraison; Chrystelle Bonnart; Emmanuelle Bitoun; Ross Robinson; Timothy J O'Brien; Kotaro Wakamatsu; Sawa Ohtsubo; Hidetoshi Takahashi; Yoshio Hashimoto; Patricia Dopping-Hepenstal; John A McGrath; Hajime Iizuka; Gabriele Richard; Alain Hovnanian
LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum.
The Journal of investigative dermatology 2005;124(2):360-6.
2004: Hidetoshi Takahashi; Hajime Iizuka
[Treatment of the keratinizing skin disorder, psoriasis, by topical vitamin D3].
Clinical calcium 2004;14(10):129-32.
2004: Hidetoshi Takahashi; Yasuhiro Itoh; Susumu Nakajima; Isao Sakata; Hajime Iizuka
A novel ATX-S10(Na) photodynamic therapy for human skin tumors and benign hyperproliferative skin.
Photodermatology, photoimmunology & photomedicine 2004;20(5):257-65.
2004: Hajime Iizuka; Hidetoshi Takahashi; Akemi Ishida-Yamamoto
Psoriatic architecture constructed by epidermal remodeling.
Journal of dermatological science 2004;35(2):93-9.
2004: Hidetoshi Takahashi; Masaru Honma; Yuki Miyauchi; Satoshi Nakamura; Akemi Ishida-Yamamoto; Hajime Iizuka
Cyclic AMP differentially regulates cell proliferation of normal human keratinocytes through ERK activation depending on the expression pattern of B-Raf.
Archives of dermatological research 2004;296(2):74-82.
2004: Akemi Ishida-Yamamoto; Michel Simon; Mari Kishibe; Yuki Miyauchi; Hidetoshi Takahashi; Shigetaka Yoshida; Timothy J O'Brien; Guy Serre; Hajime Iizuka
Epidermal lamellar granules transport different cargoes as distinct aggregates.
The Journal of investigative dermatology 2004;122(5):1137-44.
2004: Hajime Iizuka; Hidetoshi Takahashi; Masaru Honma; Akemi Ishida-Yamamoto
Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death.
The Journal of dermatology 2004;31(4):271-6.
2004: Hidetoshi Takahashi; Yuko Suzuki; Yuki Miyauchi; Yoshio Hashimoto; Akemi Ishida-Yamamoto; Hajime Iizuka
Roxithromycin decreases ultraviolet B irradiation-induced reactive oxygen intermediates production and apoptosis of keratinocytes.
Journal of dermatological science 2004;34(1):25-33.
2003: Hidetoshi Takahashi; Yasuhiro Itoh; Yuki Miyauchi; Susumu Nakajima; Isao Sakata; Akemi Ishida-Yamamoto; Hajime Iizuka
Activation of two caspase cascades, caspase 8/3/6 and caspase 9/3/6, during photodynamic therapy using a novel photosensitizer, ATX-S10(Na), in normal human keratinocytes.
Archives of dermatological research 2003;295(6):242-8.
2003: Hidetoshi Takahashi; Masaki Ibe; Masaru Honma; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
1,25-dihydroxyvitamin D(3) increases human cystatin A expression by inhibiting the Raf-1/MEK1/ERK signaling pathway of keratinocytes.
Archives of dermatological research 2003;295(2):80-7.
2003: Hajime Iizuka; Hidetoshi Takahashi; Akemi Ishida-Yamamoto
Pathophysiology of generalized pustular psoriasis.
Archives of dermatological research 2003;295 Suppl 1():S55-9.
2003: Hidetoshi Takahashi; Masaki Ibe; Motoshi Kinouchi; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Similarly potent action of 1,25-dihydroxyvitamin D3 and its analogues, tacalcitol, calcipotriol, and maxacalcitol on normal human keratinocyte proliferation and differentiation.
Journal of dermatological science 2003;31(1):21-8.
2002: Hidetoshi Takahashi; Masaki Ibe; Satoshi Nakamura; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis.
Journal of dermatological science 2002;30(2):94-9.
2002: Hiroshi Nakane; Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
Elafin, a secretory protein, is cross-linked into the cornified cell envelopes from the inside of psoriatic keratinocytes.
The Journal of investigative dermatology 2002;119(1):50-5.
2002: Hidetoshi Takahashi; Akira Manabe; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Aberrant expression of apoptosis-related molecules in psoriatic epidermis.
Journal of dermatological science 2002;28(3):187-97.
2002: Akemi Ishida-Yamamoto; Katsuhiko Sato; Takashi Wada; Hidetoshi Takahashi; Noriaki Toyota; Taiichiro Shibaki; Kousuke Yamazaki; Yoshihiko Tokusashi; Naoyuki Miyokawa; Hajime Iizuka
Fibroepithelioma-like changes occurring in perianal Paget's disease with rectal mucinous carcinoma: case report and review of 49 cases of extramammary Paget's disease.
Journal of cutaneous pathology 2002;29(3):185-9.
2002: Motoshi Kinouchi; Hidetoshi Takahashi; Yasuhiro Itoh; Akemi Ishida-Yamamoto; Hajime Iizuka
Ultraviolet B irradiation increases keratin 5 and keratin 14 expression through epidermal growth factor receptor of SV40-transformed human keratinocytes.
Archives of dermatological research 2002;293(12):634-41.
2002: Akemi Ishida-Yamamoto; Tatsuo Senshu; Robin A J Eady; Hidetoshi Takahashi; Hiroshi Shimizu; Masashi Akiyama; Hajime Iizuka
Sequential reorganization of cornified cell keratin filaments involving filaggrin-mediated compaction and keratin 1 deimination.
The Journal of investigative dermatology 2002;118(2):282-7.
2002: Hiroyuki Sakai; Katsuhiko Satoh; Akira Manabe; Hiroshi Nakane; Akemi Ishida-Yamamoto; Hajime Iizuka
Eccrine squamous syringometaplasia and syringomatous hyperplasia in association with linear scleroderma.
Dermatology (Basel, Switzerland) 2002;204(2):136-8.
2002: Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
Lessons from disorders of epidermal differentiation-associated keratins.
Histology and histopathology 2002;17(1):331-8.
2001: Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Hajime Iizuka
Ultraviolet B irradiation induces apoptosis of keratinocytes by direct activation of Fas antigen.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2001;6(1):64-8.
2001: H Tsuji; Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
Nuclear localization of beta-catenin in the hair matrix cells and differentiated keratinocytes.
Journal of dermatological science 2001;27(3):170-7.
2001: Hidetoshi Takahashi; Masaru Honma; Akemi Ishida-Yamamoto; Kazuhiko Namikawa; A Miwa; H Okado; Hiroshi Kiyama; Hajime Iizuka
In vitro and in vivo transfer of bcl-2 gene into keratinocytes suppresses UVB-induced apoptosis.
Photochemistry and photobiology 2001;74(4):579-86.
2001: Hidetoshi Takahashi; Masaru Honma; Akemi Ishida-Yamamoto; Kazuhiko Namikawa; Hiroshi Kiyama; Hajime Iizuka
Expression of human cystatin A by keratinocytes is positively regulated via the Ras/MEKK1/MKK7/JNK signal transduction pathway but negatively regulated via the Ras/Raf-1/MEK1/ERK pathway.
The Journal of biological chemistry 2001;276(39):36632-8.
2001: Hidetoshi Takahashi; Y Atsuta; K Sato; Akemi Ishida-Yamamoto; H Suzuki; Hajime Iizuka
Novel mutations of ATP2A2 gene in Japanese patients of Darier's disease.
Journal of dermatological science 2001;26(3):169-72.
2001: Hidetoshi Takahashi; Hajime Iizuka; M Nakashima; Takashi Wada; K Asano; Akemi Ishida-Yamamoto; T Watanabe
RCAS1 antigen is highly expressed in extramammary Paget's disease and in advanced stage squamous cell carcinoma of the skin.
Journal of dermatological science 2001;26(2):140-4.
2001: Satoshi Nakamura; Hidetoshi Takahashi; Motoshi Kinouchi; Akira Manabe; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes.
Journal of dermatological science 2001;25(2):139-49.
2001: S Nakamura; Akemi Ishida-Yamamoto; H Takahashi; Y Hashimoto; H Yokoo; Hajime Iizuka
Pigmented Paget's disease of the male breast: report of a case.
Dermatology (Basel, Switzerland) 2001;202(2):134-7.
2000: Akemi Ishida-Yamamoto; David P Kelsell; John Common; M J Houseman; M Hashimoto; H Shibaki; K Asano; Hidetoshi Takahashi; Yoshio Hashimoto; Tatsuo Senshu; I M Leigh; Hajime Iizuka
A case of erythrokeratoderma variabilis without mutations in connexin 31.
The British journal of dermatology 2000;143(6):1283-7.
2000: Akemi Ishida-Yamamoto; H Kato; H Kiyama; D K Armstrong; C S Munro; R A Eady; Satoshi Nakamura; Motoshi Kinouchi; Hidetoshi Takahashi; Hajime Iizuka
Mutant loricrin is not crosslinked into the cornified cell envelope but is translocated into the nucleus in loricrin keratoderma.
The Journal of investigative dermatology 2000;115(6):1088-94.
2000: Hidetoshi Takahashi; N Oyama; Y Itoh; Akemi Ishida-Yamamoto; F Kaneko; Hajime Iizuka
Transcriptional factor AP-2gamma increases human cystatin A gene transcription of keratinocytes.
Biochemical and biophysical research communications 2000;278(3):719-23.
2000: Hidetoshi Takahashi; N Aoki; Satoshi Nakamura; K Asano; Akemi Ishida-Yamamoto; Hajime Iizuka
Cornified cell envelope formation is distinct from apoptosis in epidermal keratinocytes.
Journal of dermatological science 2000;23(3):161-9.
2000: Hidetoshi Takahashi; Yoshio Hashimoto; N Aoki; Motoshi Kinouchi; Akemi Ishida-Yamamoto; Hajime Iizuka
Copper, zinc-superoxide dismutase protects from ultraviolet B-induced apoptosis of SV40-transformed human keratinocytes: the protection is associated with the increased levels of antioxidant enzymes.
Journal of dermatological science 2000;23(1):12-21.
2000: Akemi Ishida-Yamamoto; Tatsuo Senshu; Hidetoshi Takahashi; K Akiyama; K Nomura; Hajime Iizuka
Decreased deiminated keratin K1 in psoriatic hyperproliferative epidermis.
The Journal of investigative dermatology 2000;114(4):701-5.
2000: H Sakai; M Minami; E Satoh; S Matsuo; Hajime Iizuka
Keratoacanthoma developing on a pigmented patch in incontinentia pigmenti.
Dermatology (Basel, Switzerland) 2000;200(3):258-61.
1999: Akemi Ishida-Yamamoto; H Tanaka; H Nakane; Hidetoshi Takahashi; Hajime Iizuka
Antigen retrieval of loricrin epitopes at desmosomal areas of cornified cell envelopes: an immunoelectron microscopic analysis.
Experimental dermatology 1999;8(5):402-6.
1999: Akemi Ishida-Yamamoto; H Tanaka; H Nakane; Hidetoshi Takahashi; Yoshio Hashimoto; Hajime Iizuka
Programmed cell death in normal epidermis and loricrin keratoderma. Multiple functions of profilaggrin in keratinization.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1999;4(2):145-9.
1999: Hidetoshi Takahashi; Satoshi Nakamura; K Asano; Motoshi Kinouchi; Akemi Ishida-Yamamoto; Hajime Iizuka
Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process.
Experimental cell research 1999;249(2):291-8.
1999: F Ito; N Toyota; H Sakai; Hidetoshi Takahashi; Hajime Iizuka
FK506 and cyclosporin A inhibit stem cell factor-dependent cell proliferation/survival, while inducing upregulation of c-kit expression in cells of the mast cell line MC/9.
Archives of dermatological research 1999;291(5):275-83.
1999: A Ishida-Yamamoto; T Yamauchi; H Tanaka; H Nakane; Hidetoshi Takahashi; Hajime Iizuka
Electron microscopic in situ DNA nick end-labeling in combination with immunoelectron microscopy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(5):711-7.
1999: H Sakai; N Toyota; F Ito; Hidetoshi Takahashi; Yoshio Hashimoto; Hajime Iizuka
Glucocorticoids inhibit proliferation and adhesion of the IL-3-dependent mast cell line, MC/9, to NIH/3T3 fibroblasts, with an accompanying decrease in IL-3 receptor expression.
Archives of dermatological research 1999;291(4):224-31.
1999: Hidetoshi Takahashi; Akemi Ishida-Yamamoto; A Kishi; K Ohara; Hajime Iizuka
Loricrin gene mutation in a Japanese patient of Vohwinkel's syndrome.
Journal of dermatological science 1999;19(1):44-7.
1998: Akemi Ishida-Yamamoto; H Tanaka; H Nakane; Hidetoshi Takahashi; Hajime Iizuka
Inherited disorders of epidermal keratinization.
Journal of dermatological science 1998;18(3):139-54.
1998: Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Richard B Presland; Beverly A Dale; Hajime Iizuka
Translocation of profilaggrin N-terminal domain into keratinocyte nuclei with fragmented DNA in normal human skin and loricrin keratoderma.
Laboratory investigation; a journal of technical methods and pathology 1998;78(10):1245-53.
1998: Hidetoshi Takahashi; Motoshi Kinouchi; T Tamura; Akemi Ishida-Yamamoto; Hajime Iizuka
Adenylate cyclases in keratinocytes: FRSK cells express types I, II, III, IV, VI and VIII, and 1,25(OH)2D3, retinoic acid and TPA augment forskolin-induced cyclic AMP accumulation in the absence of altered isozyme expression.
Archives of dermatological research 1998;290(8):407-12.
1998: Hidetoshi Takahashi; K Asano; Motoshi Kinouchi; Akemi Ishida-Yamamoto; K D Wuepper; Hajime Iizuka
Structure and transcriptional regulation of the human cystatin A gene. The 12-O-tetradecanoylphorbol-13-acetate (TPA) responsive element-2 site (-272 to -278) on cystatin A gene is critical for TPA-dependent regulation.
The Journal of biological chemistry 1998;273(28):17375-80.
1998: Akemi Ishida-Yamamoto; Hidetoshi Takahashi; Hajime Iizuka
Loricrin and human skin diseases: molecular basis of loricrin keratodermas.
Histology and histopathology 1998;13(3):819-26.
1998: T Tamura; Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Yoshio Hashimoto; Hajime Iizuka
Functional alteration of guanine nucleotide binding proteins (Gs and Gi) in psoriatic epidermis.
Journal of dermatological science 1998;17(1):61-6.
1998: Hidetoshi Takahashi; Yoshio Hashimoto; Motoshi Kinouchi; Hajime Iizuka
Interferon-gamma-dependent induction of manganese superoxide dismutase activity of SV40-transformed human keratinocytes by anti-Fas antibody and by TNF-alpha.
Journal of dermatological science 1998;16(3):191-9.
1998: Hidetoshi Takahashi; K Asano; Akira Manabe; Motoshi Kinouchi; Akemi Ishida-Yamamoto; Hajime Iizuka
The alpha and eta isoforms of protein kinase C stimulate transcription of human involucrin gene.
The Journal of investigative dermatology 1998;110(3):218-23.
1998: Yoshio Hashimoto; Hidetoshi Takahashi; K Kishiyama; Y Sato; M Nakao; K Miyamoto; Hajime Iizuka
Lyme disease with facial nerve palsy: rapid diagnosis using a nested polymerase chain reaction-restriction fragment length polymorphism analysis.
The British journal of dermatology 1998;138(2):304-9.
1998: Akemi Ishida-Yamamoto; Hajime Iizuka
Structural organization of cornified cell envelopes and alterations in inherited skin disorders.
Experimental dermatology 1998;7(1):1-10.
1998: Yoshio Hashimoto; T Kashiwagi; H Takahashi; Hajime Iizuka
Oral-facial-digital syndrome (OFDS) type I in a patient with Werdnig-Hoffman disease.
International journal of dermatology 1998;37(1):45-8.
1997: H Tanaka; Akemi Ishida-Yamamoto; T Hashimoto; K Hiramoto; T Harada; Y Kawachi; H Shimizu; T Tanaka; K Kishiyama; B Höpfner; Hidetoshi Takahashi; Hajime Iizuka; L Bruckner-Tuderman
A novel variant of acquired epidermolysis bullosa with autoantibodies against the central triple-helical domain of type VII collagen.
Laboratory investigation; a journal of technical methods and pathology 1997;77(6):623-32.
1997: Hajime Iizuka; H Honda; Akemi Ishida-Yamamoto
Epidermal remodeling in psoriasis (II): a quantitative analysis of the epidermal architecture.
The Journal of investigative dermatology 1997;109(6):806-10.
1997: Bernhard P Korge; Akemi Ishida-Yamamoto; C Pünter; Patricia Dopping-Hepenstal; Hajime Iizuka; A Stephenson; Robin A J Eady; Colin S Munro
Loricrin mutation in Vohwinkel's keratoderma is unique to the variant with ichthyosis.
The Journal of investigative dermatology 1997;109(4):604-10.
1997: H Sakai; Y Fukami; Masaki Ibe; T Tamura; Yoshio Hashimoto; Hajime Iizuka
A verrucous lesion on skin grafted after necrotizing fasciitis in a diabetic patient successfully treated with combined topical 5-FU and tacalcitol.
The Journal of dermatology 1997;24(9):573-7.
1997: Akemi Ishida-Yamamoto; John A McGrath; H Lam; Hajime Iizuka; R A Friedman; A M Christiano
The molecular pathology of progressive symmetric erythrokeratoderma: a frameshift mutation in the loricrin gene and perturbations in the cornified cell envelope.
American journal of human genetics 1997;61(3):581-9.
1997: M M Ichikawa; A Ishida-Yamamoto; Y Hashimoto; S Matsuo; Hajime Iizuka
Venous hemangioma. An immunohistochemical and ultrastructural study.
Acta dermato-venereologica 1997;77(5):382-4.
1997: Hidetoshi Takahashi; Motoshi Kinouchi; Hajime Iizuka
Interleukin-1beta-converting enzyme and CPP32 are involved in ultraviolet B-induced apoptosis of SV40-transformed human keratinocytes.
Biochemical and biophysical research communications 1997;236(1):194-8.
1997: Akemi Ishida-Yamamoto; Yoshio Hashimoto; M Manabe; W M O'Guin; Beverly A Dale; Hajime Iizuka
Distinctive expression of filaggrin and trichohyalin during various pathways of epithelial differentiation.
The British journal of dermatology 1997;137(1):9-16.
1997: Hidetoshi Takahashi; Motoshi Kinouchi; K D Wuepper; Hajime Iizuka
Cloning of human keratolinin cDNA: keratolinin is identical with a cysteine proteinase inhibitor, cystatin A, and is regulated by Ca2+, TPA, and cAMP.
The Journal of investigative dermatology 1997;108(6):843-7.
1997: Akemi Ishida-Yamamoto; T Kartasova; S Matsuo; T Kuroki; Hajime Iizuka
Involucrin and SPRR are synthesized sequentially in differentiating cultured epidermal cells.
The Journal of investigative dermatology 1997;108(1):12-6.
1996: H Sakai; S Matsuo; M Matsumoto; Hajime Iizuka
A case of Sézary syndrome associated with cutaneous transformation.
The Journal of dermatology 1996;23(10):697-702.
1996: N Toyota; H Sakai; Hidetoshi Takahashi; Yoshio Hashimoto; Hajime Iizuka
Inhibitory effect of 1 alpha,25-dihydroxyvitamin D3 on mast cell proliferation and A23187-induced histamine release, also accompanied by a decreased c-kit receptor.
Archives of dermatological research 1996;288(11):709-15.
1996: Hajime Iizuka; Akemi Ishida-Yamamoto; H Honda
Epidermal remodelling in psoriasis.
The British journal of dermatology 1996;135(3):433-8.
1996: N Toyota; Yoshio Hashimoto; S Matsuo; Y Kitamura; Hajime Iizuka
Effects of FK506 and cyclosporin A on proliferation, histamine release and phenotype of murine mast cells.
Archives of dermatological research 1996;288(8):474-80.
1996: Hidetoshi Takahashi; Motoshi Kinouchi; T Tamura; Hajime Iizuka
Decreased beta 2-adrenergic receptor-mRNA and loricrin-mRNA, and increased involucrin-mRNA transcripts in psoriatic epidermis: analysis by reverse transcription-polymerase chain reaction.
The British journal of dermatology 1996;134(6):1065-9.
1996: Akemi Ishida-Yamamoto; Hajime Iizuka
Eccrine syringofibroadenoma (Mascaro). An ultrastructural and immunohistochemical study.
The American Journal of dermatopathology 1996;18(2):207-11.
1996: Hidetoshi Takahashi; T Tamura; Hajime Iizuka
1,25-Dihydroxyvitamin D3 increased beta-adrenergic adenylate cyclase response of fetal rat keratinizing epidermal cells (FRSK cells).
Journal of dermatological science 1996;11(2):121-8.
1996: Akemi Ishida-Yamamoto; Robin A J Eady; F M Watt; D R Roop; D Hohl; Hajime Iizuka
Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(2):167-75.
1996: Yoshio Hashimoto; Hidetoshi Takahashi; S Matsuo; K Hirai; N Takemori; M Nakao; K Miyamoto; Hajime Iizuka
Polymerase chain reaction of Borrelia burgdorferi flagellin gene in Shulman syndrome.
Dermatology (Basel, Switzerland) 1996;192(2):136-9.
1996: T Tamura; Hidetoshi Takahashi; Hajime Iizuka
Protein kinase C-dependent modulation of stimulatory guanine nucleotide binding protein of fetal rat skin keratinocytes.
Archives of dermatological research 1996;288(1):24-30.
1996: H Sakai; M Ibe; Hidetoshi Takahashi; S Matsuo; K Okamoto; I Makino; Y Oomori; Hajime Iizuka
Satisfactory remission achieved by PUVA therapy in Langerhans cell hisiocytosis in an elderly patient.
The Journal of dermatology 1996;23(1):42-6.
1995: Hidetoshi Takahashi; H Kobayashi; Yoshio Hashimoto; S Matsuo; Hajime Iizuka
Interferon-gamma-dependent stimulation of Fas antigen in SV40-transformed human keratinocytes: modulation of the apoptotic process by protein kinase C.
The Journal of investigative dermatology 1995;105(6):810-5.
1995: Hajime Iizuka
Epidermal architecture that depends on turnover time.
Journal of dermatological science 1995;10(3):220-3.
1995: Yoshio Hashimoto; M Tsutsui; S Matsuo; S Iizuka; Hajime Iizuka
Topical tacalcitol (1,24-(R)-dihydroxyvitamin D3) induces a transient increase in thymidine incorporation and calmodulin content in pig epidermis following tape stripping in vivo.
Journal of dermatological science 1995;10(3):196-202.
1995: Hidetoshi Takahashi; T Wada; S Matsuo; K Iwatsuki; Hajime Iizuka
A case of bullous pemphigoid with antibodies against intercellular 130 kd antigen.
The Journal of dermatology 1995;22(8):576-81.
1995: Yoshio Hashimoto; M Tsutsui; S Matsuo; Hajime Iizuka
Flow cytometric analysis of pig epidermal keratinocytes: effects of ultraviolet B irradiation (UVB) and topical PUVA treatment.
Journal of dermatological science 1995;10(1):16-24.
1995: Akemi Ishida-Yamamoto; Hajime Iizuka
Differences in involucrin immunolabeling within cornified cell envelopes in normal and psoriatic epidermis.
The Journal of investigative dermatology 1995;104(3):391-5.
1995: Hajime Iizuka; Hidetoshi Takahashi; Akemi Ishida-Yamamoto; Yoshio Hashimoto
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Epithelial cell biology 1995;4(1):35-41.
1995: Hidetoshi Takahashi; H Kobayashi; S Matsuo; Hajime Iizuka
Repression of involucrin gene expression by transcriptional enhancer factor 1 (TEF-1).
Archives of dermatological research 1995;287(8):740-6.
1995: Akemi Ishida-Yamamoto; Hajime Iizuka; M Manabe; W M O'Guin; D Hohl; T Kartasova; T Kuroki; D R Roop; Robin A J Eady
Altered distribution of keratinization markers in epidermolytic hyperkeratosis.
Archives of dermatological research 1995;287(8):705-11.
1995: Yoshio Hashimoto; N Kawagishi; H Sakai; Hidetoshi Takahashi; S Matsuo; M Nakao; K Miyamoto; Hajime Iizuka
Lyme disease in Japan. Analysis of Borrelia species using rRNA gene restriction fragment length polymorphism.
Dermatology (Basel, Switzerland) 1995;191(3):193-8.
1995: A Takagi; Hajime Iizuka
UVB-induced calmodulin increase in pig epidermis: analysis of the effect of the calmodulin antagonist, W-13.
Archives of dermatological research 1995;287(3-4):326-32.
1995: N Toyota; Yoshio Hashimoto; S Matsuo; Hajime Iizuka
Transforming growth factor beta 1 inhibits IL-3- and IL-4-dependent mouse connective tissue-type mast cell proliferation.
Archives of dermatological research 1995;287(2):198-201.
1994: Hajime Iizuka
Epidermal turnover time.
Journal of dermatological science 1994;8(3):215-7.
1994: Y Hashimoto; S Matsuo; Hajime Iizuka
A DNA-flow cytometric analysis of trichilemmal carcinoma, proliferating trichilemmal cyst and trichilemmal cyst.
Acta dermato-venereologica 1994;74(5):358-60.
1994: N Toyota; H Asaga; M Hirokawa; Hajime Iizuka
A case of skin metastasis from follicular thyroid carcinoma.
Dermatology (Basel, Switzerland) 1994;188(1):69-71.
1994: M Hirokawa; M Matsumoto; Hajime Iizuka
Confluent and reticulated papillomatosis: a case with concurrent acanthosis nigricans associated with obesity and insulin resistance.
Dermatology (Basel, Switzerland) 1994;188(2):148-51.
1994: M Tsutsui; T Tamura; Hidetoshi Takahashi; Yoshio Hashimoto; Hajime Iizuka
Stimulatory guanine nucleotide binding protein in pig epidermis: transient increase of the 45KDA cholera toxin substrate (Gs alpha) in the tape stripping-induced hyperproliferative state.
Epithelial cell biology 1994;3(4):161-7.
1993: Hidetoshi Takahashi; Hajime Iizuka
Neither cyclosporin A nor FK506 affects adenylate cyclase responses of fetal rat keratinizing epidermal cells (FRSK cells) at concentrations that inhibit thymidine incorporation.
Journal of dermatological science 1993;6(3):235-9.
1993: Hidetoshi Takahashi; Hajime Iizuka
Retinoid-induced beta-adrenergic inhibitory effect associated with increased thymidine incorporation of fetal rat keratinizing epidermal cells (FRSK cells).
Journal of dermatological science 1993;5(2):122-9.
1993: T Kobayashi; N Saito; N Takemori; S Iizuka; K Suzuki; N Taniguchi; Hajime Iizuka
Ultrastructural localization of superoxide dismutase in human skin.
Acta dermato-venereologica 1993;73(1):41-5.
1993: Hidetoshi Takahashi; Hajime Iizuka
Analysis of the 5'-upstream promoter region of human involucrin gene: activation by 12-O-tetradecanoylphorbol-13-acetate.
The Journal of investigative dermatology 1993;100(1):10-5.
1993: Akemi Ishida-Yamamoto; D Hohl; D R Roop; Hajime Iizuka; Robin A J Eady
Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia.
Archives of dermatological research 1993;285(8):491-8.
1992: Yoshio Hashimoto; M Tsutsui; Hajime Iizuka
Flow cytometric analysis of pig epidermal keratinocytes: effects of tape stripping.
Journal of dermatological science 1992;4(3):193-201.
1991: N Toyota; S Matsuo; Hajime Iizuka
Immunohistochemical differential diagnosis between lymphocytoma cutis and malignant lymphoma in paraffin-embedded sections.
The Journal of dermatology 1991;18(10):586-91.
1991: Hajime Iizuka; K Asano; F Ito; T Tamura; Hidetoshi Takahashi; M Tsutsui
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Biochimica et biophysica acta 1991;1093(1):95-101.
1991: T Kobayashi; M Matsumoto; Hajime Iizuka; K Suzuki; N Taniguchi
Superoxide dismutase in psoriasis, squamous cell carcinoma and basal cell epithelioma: an immunohistochemical study.
The British journal of dermatology 1991;124(6):555-9.
1991: Yoshio Hashimoto; S Matsuo; Hajime Iizuka
[A flow cytometric study of the DNA content from paraffin-embedded samples of keratoacanthoma and squamous cell carcinoma].
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology 1991;101(7):701-5.
1991: Yoshio Hashimoto; N Ohkuma; Hajime Iizuka
Reduced superoxide dismutase activity in UVB-induced hyperproliferative pig epidermis.
Archives of dermatological research 1991;283(5):317-20.
1990: Yoshio Hashimoto; M Matsumoto; N Ohkuma; Hajime Iizuka; H R Chang; M Ikenaga
[A case of xeroderma pigmentosum treated by oral etretinate].
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology 1990;100(9):947-51.
1990: Hidetoshi Takahashi; T Tamura; M Tsutsui; Hajime Iizuka
Adenylate cyclase system in fetal rat keratinizing epidermal cells (FRSK cells) and SV40-transformed human keratinocytes.
The Journal of dermatology 1990;17(8):457-64.
1990: M Hirokawa; Yoshio Hashimoto; N Ohkuma; T Mizumoto; Hajime Iizuka
Reversible inhibition of keratinocyte thymidine incorporation by the calmodulin antagonist, W-7.
The Journal of dermatology 1990;17(7):403-8.
1990: Yoshio Hashimoto; N Ohkuma; Hajime Iizuka
Effects of retinoids on DNA synthesis of pig epidermis: its relation to epidermal beta-adrenergic adenylate cyclase response and to epidermal superoxide dismutase activity.
Journal of dermatological science 1990;1(4):303-9.
1990: Hajime Iizuka; H Sakai; Motoshi Kinouchi
Epidermal adenylate cyclase system is regulated by diacylglycerol-protein kinase C signal, but not by calcium signal.
The British journal of dermatology 1990;122(4):459-67.
1990: Hidetoshi Takahashi; Hajime Iizuka; M Katagiri
No evidence for the mutation of ras gene in psoriatic epidermis.
Archives of dermatological research 1990;282(1):8-11.
1990: Hidetoshi Takahashi; N Miyokawa; M Katagiri; Hajime Iizuka
Expression of guanine nucleotide binding proteins, Gs and Gi, in mRNAs in epidermal keratinocytes.
Archives of dermatological research 1990;282(6):392-6.
1990: M Tsutsui; Hajime Iizuka
Inhibitory guanine nucleotide binding protein in pig epidermis: regulation of epidermal adenylate cyclase.
Archives of dermatological research 1990;282(7):469-74.
1990: S Matsuo; Hajime Iizuka
Cholera toxin- and forskolin-induced cyclic AMP accumulations of pig skin (epidermis). Modulation by chemicals which reveal the beta-adrenergic augmentation effect.
Journal of dermatological science 1990;1(1):7-13.
1989: Hajime Iizuka; H Sakai; T Tamura
Effects of the tumor promoter, phorbol 12-myristate, 13-acetate, on the epidermal adenylate cyclase system: evidence for adenylate cyclase-regulation by protein kinase C.
The Journal of investigative dermatology 1989;93(3):387-91.
1988: Hajime Iizuka; S Matsuo; T Tamura; N Ohkuma
Increased cholera toxin-, and forskolin-induced cyclic AMP accumulations in psoriatic involved versus uninvolved or normal human epidermis.
The Journal of investigative dermatology 1988;91(2):154-7.
1988: Hajime Iizuka; Akemi Ishida-Yamamoto; S Kajita; M Tsutsui; N Ohkuma
Effects of UVB irradiation on epidermal adenylate cyclase responses in vitro: its relation to sunburn cell formation.
Archives of dermatological research 1988;280(3):163-7.
1987: N Ohkuma; S Kajita; Hajime Iizuka
Superoxide dismutase in epidermis: its relation to keratinocyte proliferation.
The Journal of dermatology 1987;14(6):562-8.
1987: M Tsutsui; Hajime Iizuka; A Ohkawara; K Adachi; T Kanzaki
Adenylate cyclase system of human trichilemmoma cell line.
Archives of dermatological research 1987;279(8):530-5.
1987: S Kajita; Hajime Iizuka
Melittin-induced alteration of epidermal adenylate cyclase responses.
Acta dermato-venereologica 1987;67(4):295-300.
1985: T Mizumoto; Yoshio Hashimoto; M Hirokawa; N Ohkuma; Hajime Iizuka; A Ohkawara
Calmodulin activities are significantly increased in both uninvolved and involved epidermis in psoriasis.
The Journal of investigative dermatology 1985;85(5):450-2.