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Kazuro Ikawa

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Kazuro Ikawa; Kayo Ikeda; Naru Kondo; Norifumi Morikawa; Yoshiaki Murakami; Akira Nakashima; Hiroki Ohge; Kenichi Yoshizawa; Taijiro Sueda
Penetration of meropenem into human pancreatic juice.
Kenichi Yoshizawa; Hiroki Ohge; Kazuro Ikawa; Kayo Ikeda; Hiromi Kumon; Norifumi Morikawa
Optimisation of imipenem regimens in patients with impaired renal function by pharmacokinetic-pharmacodynamic target attainment analysis of plasma and urinary concentration data.
Kayo Ikeda; Toshihiro Kozumi; Shunji Horikawa; Kazuro Ikawa; Satoko Yokoshige; Norifumi Morikawa
Development and validation of a GC-EI-MS method with reduced adsorption loss for the quantification of olanzapine in human plasma.

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2013: Kazuro Ikawa; Kayo Ikeda; Naru Kondo; Norifumi Morikawa; Yoshiaki Murakami; Akira Nakashima; Hiroki Ohge; Kenichi Yoshizawa; Taijiro Sueda
Penetration of meropenem into human pancreatic juice.
Scandinavian journal of infectious diseases 2013;45(5):404-6.
2012: Kenichi Yoshizawa; Hiroki Ohge; Kazuro Ikawa; Kayo Ikeda; Hiromi Kumon; Norifumi Morikawa
Optimisation of imipenem regimens in patients with impaired renal function by pharmacokinetic-pharmacodynamic target attainment analysis of plasma and urinary concentration data.
International journal of antimicrobial agents 2012;40(5):427-33.
2012: Kayo Ikeda; Toshihiro Kozumi; Shunji Horikawa; Kazuro Ikawa; Satoko Yokoshige; Norifumi Morikawa
Development and validation of a GC-EI-MS method with reduced adsorption loss for the quantification of olanzapine in human plasma.
Analytical and bioanalytical chemistry 2012;403(7):1823-30.
2011: Kazuro Ikawa; Kayo Ikeda; Norifumi Morikawa; Yoshiaki Murakami; Akira Nakashima; Hiroki Ohge; Hartmut Derendorf; Taijiro Sueda
Clinical pharmacokinetics of meropenem and biapenem in bile and dosing considerations for biliary tract infections based on site-specific pharmacodynamic target attainment.
Antimicrobial agents and chemotherapy 2011;55(12):5609-15.
2010: Keiko Kameda; Kazuro Ikawa; Kayo Ikeda; Norifumi Morikawa; Akira Nakashima; Hiroki Ohge; Taijiro Sueda
HPLC method for measuring meropenem and biapenem concentrations in human peritoneal fluid and bile: application to comparative pharmacokinetic investigations.
Journal of chromatographic science 2010;48(5):406-11.
2010: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Mizuka Miki; Masao Kobayashi
Population pharmacokinetics and pharmacodynamics of meropenem in Japanese pediatric patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2010;16(2):139-43.
2010: Kazuro Ikawa; Norifumi Morikawa; Hiroki Ohge; Kayo Ikeda; Taijiro Sueda; Masafumi Taniwaki; Kaoru Kurisu
Pharmacokinetic–pharmacodynamic target attainment analysis of meropenem in Japanese adult patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2010;16(1):25-32.
2009: Kazuro Ikawa; Norifumi Morikawa; Hidemichi Suyama; Kayo Ikeda; Takao Yamanoue
Pharmacokinetics and pharmacodynamics of once-daily arbekacin during continuous venovenous hemodiafiltration in critically ill patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2009;15(6):420-3.
2009: Kazuro Ikawa; Toshihiro Kozumi; Kayo Ikeda; Norifumi Morikawa; Ryoji Kobayashi
Population pharmacokinetic modeling and pharmacodynamic assessment of cefozopran in pediatric patients.
The Japanese journal of antibiotics 2009;62(5):435-44.
2009: Kazuro Ikawa; Kenichi Nomura; Norifumi Morikawa; Kayo Ikeda; Masafumi Taniwaki
Assessment of micafungin regimens by pharmacokinetic-pharmacodynamic analysis: a dosing strategy for Aspergillus infections.
The Journal of antimicrobial chemotherapy 2009;64(4):840-4.
2009: Kazuro Ikawa
[Personalized optimization of beta-lactam regimens based on studies of the pharmacokinetics-pharmacodynamics at the target sites].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2009;129(7):821-7.
2009: Kayo Ikeda; Kazuro Ikawa; Norifumi Morikawa; Hiroki Ohge; Taijiro Sueda
Determination of total cefozopran concentrations in human peritoneal fluid by HPLC with cefepime as an internal standard: Comparative pharmacokinetics in the fluid and plasma.
Journal of pharmaceutical and biomedical analysis 2009;49(4):1075-81.
2009: Kazuro Ikawa; Norifumi Morikawa; Shinya Uehara; Koichi Monden; Yoshiaki Yamada; Nobuaki Honda; Hiromi Kumon
Pharmacokinetic-pharmacodynamic target attainment analysis of doripenem in infected patients.
International journal of antimicrobial agents 2009;33(3):276-9.
2009: Keiko Kameda; Mizuka Miki; Kazuro Ikawa; Norifumi Morikawa; Masao Kobayashi
[Dosing regimen rationalization of biapenem in pediatric patients: use of Monte Carlo simulation].
The Japanese journal of antibiotics 2009;62(1):1-8.
2008: K Fukuhara; Kazuro Ikawa; Norifumi Morikawa; K Kumagai
Population pharmacokinetics of high-dose methotrexate in Japanese adult patients with malignancies: a concurrent analysis of the serum and urine concentration data.
Journal of clinical pharmacy and therapeutics 2008;33(6):677-84.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Pharmacodynamic assessment of doripenem in peritoneal fluid against Gram-negative organisms: use of population pharmacokinetic modeling and Monte Carlo simulation.
Diagnostic microbiology and infectious disease 2008;62(3):292-7.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Pharmacodynamic evaluation of biapenem in peritoneal fluid using population pharmacokinetic modelling and Monte Carlo simulation.
International journal of antimicrobial agents 2008;32(4):339-43.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Development of breakpoints of carbapenems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in peritoneal fluid.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(4):330-2.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Ryu Tsumura; Masaaki Shibukawa; Koji Iida; Kaoru Kurisu
Considerations of meropenem dosage for bacterial meningitis based on pharmacodynamics in cerebrospinal fluid.
International journal of antimicrobial agents 2008;32(1):96-8.
2008: Kayo Ikeda; Kazuro Ikawa; Norifumi Morikawa; Keiko Kameda; Nami Urakawa; Hiroki Ohge; Taijiro Sueda
Quantification of doripenem in human plasma and peritoneal fluid by high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;867(1):20-5.
2008: Kazuro Ikawa; Hiroshige Mikamo; Norifumi Morikawa; Kayo Ikeda; Teruhiko Tamaya
Penetration into and exposure of cefozopran in pelvic retroperitoneal space exudate.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(2):170-1.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Development of breakpoints of cephems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in the peritoneal fluid of patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(2):141-6.
2008: Kazuro Ikawa; Kenichi Nomura; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda; Masafumi Taniwaki
Pharmacokinetic-pharmacodynamic target attainment analysis of cefozopran in Japanese adult patients.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(2):130-6.
2008: Kazuko Higuchi; Kazuro Ikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda; Hitoshi Houchi; Norifumi Morikawa
Peritoneal pharmacokinetics of cefepime in laparotomy patients with inflammatory bowel disease, and dosage considerations for surgical intra-abdominal infections based on pharmacodynamic assessment.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(2):110-6.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; M Miki; Shin-Ichiro Nishimura; Masao Kobayashi
Population pharmacokinetics and pharmacodynamics of biapenem in paediatric patients.
Journal of clinical pharmacy and therapeutics 2008;33(2):203-10.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hidemichi Suyama
Pharmacokinetic modeling and dosage adaptation of biapenem in Japanese patients during continuous venovenous hemodiafiltration.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(1):35-9.
2008: Kazuro Ikawa; Norifumi Morikawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda; Hidemichi Suyama; Masao Doi; Masao Kuwabara
Pharmacokinetic-pharmacodynamic target attainment analysis of biapenem in adult patients: a dosing strategy.
Chemotherapy 2008;54(5):386-94.
2008: Kazuro Ikawa; Norifumi Morikawa; Kenichi Sakamoto; Kayo Ikeda; Hiroki Ohge; Yoshio Takesue; Taijiro Sueda
Pharmacokinetics and pharmacodynamic assessment of imipenem in the intraperitoneal fluid of abdominal surgery patients.
Chemotherapy 2008;54(2):131-9.
2007: Kayo Ikeda; Norifumi Morikawa; Misa Kuribayashi; Kazuro Ikawa; Kenichi Nomura; Masafumi Taniwaki
Real-time therapeutic drug monitoring of cefozopran in plasma using high-performance liquid chromatography with ultraviolet detection.
Journal of pharmaceutical and biomedical analysis 2007;45(5):811-6.
2007: Kazuro Ikawa; Norifumi Morikawa; Nami Urakawa; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patients.
The Journal of antimicrobial chemotherapy 2007;60(6):1395-7.
2007: Kazuro Ikawa; Norifumi Morikawa; Shusaku Matsuda; Kayo Ikeda; Hiroki Ohge; Yoshio Takesue; Taijiro Sueda
Peritoneal penetration and pharmacodynamic exposure of intravenous cefozopran in abdominal surgery patients.
International journal of antimicrobial agents 2007;30(4):352-5.
2007: Kazuro Ikawa; Norifumi Morikawa; Seiichi Hayato; Kayo Ikeda; Hiroki Ohge; Taijiro Sueda
Pharmacokinetic and pharmacodynamic profiling of cefepime in plasma and peritoneal fluid of abdominal surgery patients.
International journal of antimicrobial agents 2007;30(3):270-3.
2007: Kayo Ikeda; Kazuro Ikawa; Norifumi Morikawa; Mizuka Miki; Shin-Ichiro Nishimura; Masao Kobayashi
High-performance liquid chromatography with ultraviolet detection for real-time therapeutic drug monitoring of meropenem in plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;856(1-2):371-5.
2007: Kazuro Ikawa; Tomohiko Shimatani; Seiichi Hayato; Norifumi Morikawa; Susumu Tazuma
Pharmacokinetic and pharmacodynamic properties of lafutidine after postprandial oral administration in healthy subjects: comparison with famotidine.
Biological & pharmaceutical bulletin 2007;30(5):1003-6.
2007: Tomohiko Shimatani; Masaki Inoue; Tomoko Kuroiwa; Mutsuko Moriwaki; Jing Xu; Kazuro Ikawa; Norifumi Morikawa; Susumu Tazuma
Which has superior acid-suppressive effect, 10 mg omeprazole once daily or 20 mg famotidine twice daily? Effects of single or repeated administration in Japanese Helicobacter pylori-negative CYP2C19 extensive metabolizers.
Digestive diseases and sciences 2007;52(2):390-5.
2006: Kayo Ikeda; Kazuro Ikawa; Aki Ikeda; Yoshimi Nishikawa; Norifumi Morikawa
A simple and rapid determination of biapenem in plasma by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;844(1):148-52.
2006: Rintaro Kamikawa; Kazuro Ikawa; Norifumi Morikawa; Hideki Asaoku; Koji Iwato; Ayako Sasaki
The pharmacokinetics of low-dose thalidomide in Japanese patients with refractory multiple myeloma.
Biological & pharmaceutical bulletin 2006;29(11):2331-4.
2006: Kazuro Ikawa; Tomohiko Shimatani; Y Azuma; Masayasu Inoue; Norifumi Morikawa
Calcitonin gene-related peptide and somatostatin releases correlated with the area under the lafutidine concentration-time curve in human plasma.
Journal of clinical pharmacy and therapeutics 2006;31(4):351-6.
2006: Tomohiko Shimatani; Masaki Inoue; Tomoko Kuroiwa; Jing Xu; Masuo Nakamura; Susumu Tazuma; Kazuro Ikawa; Norifumi Morikawa
Lafutidine, a newly developed antiulcer drug, elevates postprandial intragastric pH and increases plasma calcitonin gene-related peptide and somatostatin concentrations in humans: comparisons with famotidine.
Digestive diseases and sciences 2006;51(1):114-20.