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Kenji Ikeda

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Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy with miriplatin for hepatocellular carcinoma patients with chronic renal failure: report of three cases.
Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Tetsuro Kobayashi
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.

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All Publications

2013: Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Emergence of telaprevir-resistant variants detected by ultra-deep sequencing after triple therapy in patients infected with HCV genotype 1.
Journal of medical virology 2013;85(6):1028-36.
2013: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy with miriplatin for hepatocellular carcinoma patients with chronic renal failure: report of three cases.
Gut and liver 2013;7(2):246-51.
2013: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Tetsuro Kobayashi
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C.
Hepatology (Baltimore, Md.) 2013;57(3):964-73.
2013: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Efficacy and anticarcinogenic activity of ribavirin combination therapy for hepatitis C virus-related compensated cirrhosis.
Intervirology 2013;56(1):37-45.
2013: Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C Virus core region and lipid metabolism are associated with hepatocarcinogenesis in nonresponders to interferon plus ribavirin combination therapy.
Intervirology 2013;56(1):13-21.
2012: Norio Akuta; Yasuji Arase; Tasuku Hara; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2012;56(6):2134-41.
2012: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy.
Journal of medical virology 2012;84(10):1593-9.
2012: Yasuji Arase; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 1b and high viral load.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(10):949-57.
2012: Atsushi Ono; Satoshi Saitou; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients.
Journal of hepatology 2012;57(3):508-14.
2012: Nami Mori; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Hiromitsu Kumada
Determinants of the clinical outcome of patients with severe acute exacerbation of chronic hepatitis B virus infection.
Journal of gastroenterology 2012;47(9):1022-9.
2012: Masatoshi Kudo; Ryosuke Tateishi; Tatsuya Yamashita; Junji Furuse; Kenji Ikeda; Masafumi Ikeda; Namiki Izumi; Norihiro Kokudo; Osamu Matsui
Current status of hepatocellular carcinoma treatment in Japan: case study and discussion-voting system.
Clinical drug investigation 2012;32 Suppl 2():37-51.
2012: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy of reduction therapy of natural human β-interferon and ribavirin in elderly patients with chronic hepatitis C, genotype 2 and high virus load.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(8):750-6.
2012: Makiko Takeyasu; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Long-term interferon monotherapy reduces the risk of HCV-associated hepatocellular carcinoma.
Journal of medical virology 2012;84(8):1199-207.
2012: Fumitaka Suzuki; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Yuzo Miyakawa; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada
Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2012;54(4):352-4.
2012: Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Determinants of response to triple therapy of telaprevir, peginterferon, and ribavirin in previous non-responders infected with HCV genotype 1.
Journal of medical virology 2012;84(7):1097-105.
2012: Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Hiromitsu Kumada
Long-term efficacy of interferon therapy in patients with chronic hepatitis B virus infection in Japan.
Journal of gastroenterology 2012;47(7):814-22.
2012: Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada; Kaoru Aida; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Tetsuro Kobayashi
Prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhosis with fasting plasma glucose level of <126 mg/dL.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(6):558-63.
2012: Mariko Kobayashi; Norio Akuta; Yasuji Arase; Kazuaki Chayama; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Yuzo Miyakawa; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.
Journal of gastroenterology 2012;47(5):596-605.
2012: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Transcatheter arterial chemotherapy using miriplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma.
Japanese journal of clinical oncology 2012;42(3):175-82.
2012: Yasuji Arase; Tetsuya Hosaka; Shiun Dong Hsieh; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Hiromitsu Kumada; Naoki Matsumoto; Kyoko Ogawa; Yuki Ohmoto; Satoshi Saito; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Maho Tanabe; Hiroshi Tsuji; Norio Akuta; Kazuhisa Amakawa; Tetsuro Kobayashi
Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(3):264-72.
2012: Youta Torii; Hirotaka Sekiguchi; Haruhiko Akiyama; Tetsuaki Arai; Chikako Habuchi; Minako Hagikura; Kenji Ikeda; Shuji Iritani; Norio Ozaki
Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: a postmortem study.
Schizophrenia research 2012;134(2-3):137-42.
2012: Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Kazuhisa Amakawa; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yuki Ohmoto; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiroshi Tsuji; Hiromitsu Kumada
Large-scale long-term follow-up study of Japanese patients with non-alcoholic Fatty liver disease for the onset of hepatocellular carcinoma.
The American journal of gastroenterology 2012;107(2):253-61.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Intervirology 2012;55(3):231-41.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromi Yatsuji; Hiromitsu Kumada
Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Intervirology 2012;55(6):417-25.
2011: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Naoki Matsumoto; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
[Transcatheter arterial chemotherapy with miriplatin for patients with hepatocellular carcinoma and chronic renal failure].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(11):1872-8.
2011: Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Highly sensitive AFP-L3% assay is useful for predicting recurrence of hepatocellular carcinoma after curative treatment pre- and postoperatively.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(11):1036-45.
2011: Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hiromitsu Kumada
Heterogeneous type 4 enhancement of hepatocellular carcinoma on dynamic CT is associated with tumor recurrence after radiofrequency ablation.
AJR. American journal of roentgenology 2011;197(4):W665-73.
2011: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Naoki Matsumoto; Kyoko Ogawa; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Development rate of chronic kidney disease in hepatitis C virus patients with advanced fibrosis after interferon therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(10):946-54.
2011: Daiki Miki; Takashi Morizono; Yusuke Nakamura; Hidenori Ochi; Joji Toyota; Tatsuhiko Tsunoda; Tadahiko Yoshima; C Nelson Hayes; Kenji Ikeda; Naoyuki Kamatani; Michiaki Kubo; Hiromitsu Kumada; Hiromi Abe; Hiroshi Aikata; Kazuaki Chayama
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Nature genetics 2011;43(8):797-800.
2011: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy.
Journal of medical virology 2011;83(6):1016-22.
2011: Yasuji Arase; Fumitaka Suzuki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yusuke Kawamura; Naoki Matsumoto; Norio Akuta; Norihisa Imai; Mariko Kobayashi; Hitomi Sezaki; Satoshi Saito; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada; Yuki Ohmoto; Kazuhisa Amakawa; Hiroshi Tsuji; Shiun Dong Hsieh; Tetsurou Kobayashi
Efficacy and safety in sitagliptin therapy for diabetes complicated by chronic liver disease caused by hepatitis C virus.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(6):524-9.
2011: Kenji Ikeda; Masahiro Kobayashi; Yusuke Kawamura; Norihiro Imai; Yuya Seko; Miharu Hirakawa; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Stage progression of small hepatocellular carcinoma after radical therapy: comparisons of radiofrequency ablation and surgery using the Markov model.
Liver international : official journal of the International Association for the Study of the Liver 2011;31(5):692-9.
2011: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saito; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Kazuaki Chayama; Naoyuki Kamatani; Yusuke Nakamura; Yuzo Miyakawa; Hiromitsu Kumada
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Hepatology (Baltimore, Md.) 2011;53(2):415-21.
2011: Kenji Ikeda; Naoki Utoguchi; Hidenobu Tsutsui; Satoko Yamaue; Manami Homemoto; Erina Nakao; Yumi Hukunaga; Kyohei Yamasaki; Michiaki Myotoku; Yoshihiko Hirotani
In vitro approaches to evaluate placental drug transport by using differentiating JEG-3 human choriocarcinoma cells.
Basic & clinical pharmacology & toxicology 2011;108(2):138-45.
2011: Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Norihiro Imai; Yusuke Kawamura; Mariko Kobayashi; Masahiro Kobayashi; Naoki Matsumoto; Satoshi Saito; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients.
Internal medicine (Tokyo, Japan) 2011;50(19):2083-8.
2011: Tomoji Takigawa; Mikito Hayakawa; Kenji Ikeda; Yuji Matsumaru; Akira Matsumura
Transarterial embolization with use of lipiodol and gelatin sponge for active nasal bleeding from hepatocellular carcinoma metastasis in the pituitary gland.
Neurologia medico-chirurgica 2011;51(8):592-5.
2011: Norihiro Imai; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Yasuji Arase; Tetsuya Hosaka; Kenji Ikeda; Satoshi Saitoh; Yuya Seko; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Previous chemoembolization response after transcatheter arterial chemoembolization (TACE) can predict the anti-tumor effect of subsequent TACE with miriplatin in patients with recurrent hepatocellular carcinoma.
Oncology 2011;80(3-4):188-94.
2011: Yasuji Arase; Fumitaka Suzuki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yusuke Kawamura; Naoki Matsumoto; Norio Akuta; Mariko Kobayashi; Hitomi Sezaki; Satoshi Saito; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada; Yuki Ohmoto; Kazuhisa Amakawa; Hiroshi Tsuji; Shiun Dong Hsieh; Kazuhisa Kato; Maho Tanabe; Kyoko Ogawa; Shigeko Hara; Tetsuro Kobayashi
The development of chronic kidney disease in Japanese patients with non-alcoholic fatty liver disease.
Internal medicine (Tokyo, Japan) 2011;50(10):1081-7.
2011: Masaya Kawase; Tadashi Saito; Masafumi Ogawa; Hideki Uejima; Yasutoshi Hatsuda; Sonoyo Kawanishi; Yoshihiko Hirotani; Michiaki Myotoku; Kenji Ikeda; Hiroki Konishi; Ikumi Iga; Junji Yamakawa; Seizi Nishizawa; Kohji Yamamoto; Masahiko Tani
Application of terahertz absorption spectroscopy to evaluation of aging variation of medicine.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2011;27(2):209-12.
2010: Kenji Ikeda; Masahiro Kobayashi; Yuya Seko; Norihiro Imai; Miharu Hirakawa; Yusuke Kawamura; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: A retrospective study of hepatitis C virus-related liver cancer.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(12):1168-75.
2010: Tetsuya Hosaka; Fumitaka Suzuki; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(10):1461-70.
2010: Yusuke Kawamura; Yasuji Arase; Kenji Ikeda; Miharu Hirakawa; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Diabetes enhances hepatocarcinogenesis in noncirrhotic, interferon-treated hepatitis C patients.
The American journal of medicine 2010;123(10):951-956.e1.
2010: Yusuke Kawamura; Kenji Ikeda; Miharu Hirakawa; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
New classification of dynamic computed tomography images predictive of malignant characteristics of hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(10):1006-14.
2010: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; Yusuke Nakamura; Hiromitsu Kumada
Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Hepatology (Baltimore, Md.) 2010;52(2):421-9.
2010: Yoshiyuki Suzuki; Kenji Ikeda; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Fumitaka Suzuki; Satoshi Saitoh; Yasuji Arase; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Association of HLA-DR14 with the treatment response in Japanese patients with autoimmune hepatitis.
Digestive diseases and sciences 2010;55(7):2070-6.
2010: Kenji Ikeda
[Current therapy for hepatocellular carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(6):1129-36.
2010: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Efficacy of switching to entecavir monotherapy in Japanese lamivudine-pretreated patients.
Journal of gastroenterology and hepatology 2010;25(5):892-8.
2010: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region of genotype 1b affect very early viral dynamics during treatment with telaprevir, peginterferon, and ribavirin.
Journal of medical virology 2010;82(4):575-82.
2010: Yoshimasa Hashimoto; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saito; Yoshiyuki Suzuki; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Clinical and virological effects of long-term (over 5 years) lamivudine therapy.
Journal of medical virology 2010;82(4):684-91.
2010: Tetsuaki Arai; Masato Hasegawa; Takashi Nonoka; Fuyuki Kametani; Makiko Yamashita; Masato Hosokawa; Kazuhiro Niizato; Kuniaki Tsuchiya; Zen Kobayashi; Kenji Ikeda; Mari Yoshida; Mitsumoto Onaya; Hiroshige Fujishiro; Haruhiko Akiyama
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2010;30(2):170-81.
2010: Yusuke Kawamura; Kenji Ikeda; Hiromitsu Kumada
[Strategy for advanced hepatocellular carcinoma unresponsive to transcatheter arterial chemoembolization using epirubicin].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(3):402-7.
2010: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Hitomi Sezaki; Tetsuya Hosaka; Yusuke Kawamura; Hiromi Yatsuji; Miharu Hirakawa; Kenji Ikeda; Shiun Dong Hsieh; Yuki Oomoto; Kazuhisa Amakawa; Hisahito Kato; Tamae Kazawa; Hiroshi Tsuji; Tetsuro Kobayashi; Hiromitsu Kumada
Virus clearance reduces bone fracture in postmenopausal women with osteoporosis and chronic liver disease caused by hepatitis C virus.
Journal of medical virology 2010;82(3):390-5.
2010: Kenji Ikeda; Takuji Okusaka; Masafumi Ikeda; Manabu Morimoto
[Transcatheter arterial chemoembolization with a lipophilic platinum complex SM-11355(miriplatin hydrate)--safety and efficacy in combination with embolizing agents].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(2):271-5.
2010: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Yusuke Kawamura; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Hiromitsu Kumada
Correlation of YMDD mutation and breakthrough hepatitis with hepatitis B virus DNA and serum ALT during lamivudine treatment.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(2):125-34.
2010: Tetsuya Hosaka; Fumitaka Suzuki; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yastuji; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Development of HCC in patients receiving adefovir dipivoxil for lamivudine-resistant hepatitis B virus mutants.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(2):145-52.
2010: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Naoki Matsumoto; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 2 and high virus load.
Internal medicine (Tokyo, Japan) 2010;49(11):965-70.
2010: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Efficacy and safety of combination therapy of natural human interferon beta and ribavirin in chronic hepatitis C patients with genotype 1b and high virus load.
Internal medicine (Tokyo, Japan) 2010;49(11):957-63.
2010: Norio Akuta; Fumitaka Suzuki; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Extending combination therapy with peginterferon plus ribavirin for genotype 2 chronic hepatitis C virological responders: a pilot study of 7 cases.
Intervirology 2010;53(3):188-92.
2010: Kenji Ikeda
[Anti-viral treatment for liver cirrhosis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2010;107(1):8-13.
2010: Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Influence of amino-acid polymorphism in the core protein on progression of liver disease in patients infected with hepatitis C virus genotype 1b.
Journal of medical virology 2010;82(1):41-8.
2010: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Hiromi Yatsuji; Yasuji Arase; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Hiromitsu Kumada
Sustained virological response in a patient with chronic hepatitis C treated by monotherapy with the NS3-4A protease inhibitor telaprevir.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2010;47(1):76-8.
2009: Kenji Ikeda
[FTLD-U and Pick disease without Pick bodies--a clinical and pathological review].
Brain and nerve = Shinkei kenkyū no shinpo 2009;61(11):1328-36.
2009: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(11):1056-63.
2009: Yujin Hoshida; Sebastian M B Nijman; Masahiro Kobayashi; Jennifer A Chan; Jean-Philippe Brunet; Derek Chiang; Augusto Villanueva; Philippa Newell; Kenji Ikeda; Masaji Hashimoto; Goro Watanabe; Stacey Gabriel; Scott L Friedman; Hiromitsu Kumada; Josep M Llovet; Todd R Golub
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma.
Cancer research 2009;69(18):7385-92.
2009: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada; Tetsuro Kobayashi
Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C.
Journal of medical virology 2009;81(9):1584-90.
2009: Hajime Isomoto; H Nishiyama; N Yamaguchi; E Fukuda; H Ishii; Kenji Ikeda; K Ohnita; K Nakao; S Kohno; Saburo Shikuwa
Clinicopathological factors associated with clinical outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms.
Endoscopy 2009;41(8):679-83.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.
Journal of medical virology 2009;81(6):1032-9.
2009: Kenji Ikeda; Masahiro Kobayashi; Takashi Someya; Satoshi Saitoh; Tetsuya Hosaka; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Occult hepatitis B virus infection increases hepatocellular carcinogenesis by eight times in patients with non-B, non-C liver cirrhosis: a cohort study.
Journal of viral hepatitis 2009;16(6):437-43.
2009: Hitomi Sezaki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Poor response to pegylated interferon and ribavirin in older women infected with hepatitis C virus of genotype 1b in high viral loads.
Digestive diseases and sciences 2009;54(6):1317-24.
2009: Masanori Abe; Kazuyoshi Okada; T Maruyama; Kenji Ikeda; F Kikuchi; Kazo Kaizu; Koichi Matsumoto
Comparison of the effects of polysulfone and polyester-polymer alloy dialyzers on glycemic control in diabetic patients undergoing hemodialysis.
Clinical nephrology 2009;71(5):514-20.
2009: Kenji Ikeda; Yasuji Arase; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Necessities of interferon therapy in elderly patients with chronic hepatitis C.
The American journal of medicine 2009;122(5):479-86.
2009: Daisuke Morihara; Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Hiromi Saneto; Hiromi Yatuji; Tetuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitu Kumada
Effectiveness of combination therapy of splenectomy and long-term interferon in patients with hepatitis C virus-related cirrhosis and thrombocytopenia.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(5):439-47.
2009: Tetsuya Hosaka; Kenji Ikeda; Masahiro Kobayashi; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
Predictive factors of advanced recurrence after curative resection of small hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(5):736-42.
2009: Yusuke Kawamura; Kenji Ikeda; Miharu Hirakawa; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Efficacy of platinum analogue for advanced hepatocellular carcinoma unresponsive to transcatheter arterial chemoembolization with epirubicin.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(4):346-54.
2009: Yoshiyuki Suzuki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Yuzo Miyakawa; Hiromitsu Kumada
Efficacy of entecavir treatment for lamivudine-resistant hepatitis B over 3 years: histological improvement or entecavir resistance?
Journal of gastroenterology and hepatology 2009;24(3):429-35.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
A matched case-controlled study of 48 and 72 weeks of peginterferon plus ribavirin combination therapy in patients infected with HCV genotype 1b in Japan: amino acid substitutions in HCV core region as predictor of sustained virological response.
Journal of medical virology 2009;81(3):452-8.
2009: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Kenji Ikeda; Hiromitsu Kumada
Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C.
Hepatology (Baltimore, Md.) 2009;49(3):739-44.
2009: Hajime Isomoto; Saburo Shikuwa; N Yamaguchi; Eiichiro Fukuda; Kenji Ikeda; H Nishiyama; Ken Ohnita; Yohei Mizuta; J Shiozawa; Shigeru Kohno
Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study.
Gut 2009;58(3):331-6.
2009: Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma.
Cancer 2009;115(3):571-80.
2009: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 2a high viral load and virological response to interferon-ribavirin combination therapy.
Intervirology 2009;52(6):301-9.
2009: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
The efficacy of interferon-beta monotherapy for elderly patients with type C hepatitis of genotype 2.
Internal medicine (Tokyo, Japan) 2009;48(16):1337-42.
2009: Suguru Ogura; Norio Akuta; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological and biochemical features in elderly HCV patients with hepatocellular carcinoma: amino acid substitutions in HCV core region as predictor of mortality after first treatment.
Intervirology 2009;52(4):179-88.
2009: Yasuji Arase; Fumitaka Suzuki; Kenji Ikeda; Hiromitsu Kumada; Hiroshi Tsuji; Tetsuro Kobayashi
Multivariate analysis of risk factors for the development of type 2 diabetes in nonalcoholic fatty liver disease.
Journal of gastroenterology 2009;44(10):1064-70.
2009: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Rie Mineta; Satomi Iwasaki; Sachiyo Watahiki; Yuzo Miyakawa; Hiromitsu Kumada
Development of hepatocellular carcinoma in elderly patients with chronic hepatitis C with or without elevated aspartate and alanine aminotransferase levels.
Scandinavian journal of gastroenterology 2009;44(8):975-83.
2009: Hitomi Sezaki; Fumitaka Suzuki; Norio Akuta; Hiromi Yatsuji; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
An open pilot study exploring the efficacy of fluvastatin, pegylated interferon and ribavirin in patients with hepatitis C virus genotype 1b in high viral loads.
Intervirology 2009;52(1):43-8.
2009: Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Combination therapy of peginterferon and ribavirin for chronic hepatitis C patients with genotype 1b and low-virus load.
Internal medicine (Tokyo, Japan) 2009;48(5):253-8.
2008: Shuji Iritani; Kuniaki Tsuchiya; Tetsuaki Arai; Haruhiko Akiyama; Kenji Ikeda
An atypical autopsy case of Lewy body disease with clinically diagnosed major depression: a clinical, radiological and pathological study.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(6):652-9.
2008: Mariko Kobayashi; Kenji Ikeda; Yasuji Arase; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Masahiro Kobayashi; Yoshiyuki Suzuki; Sachiyo Watahiki; Rie Mineta; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Change of hepatitis B virus genotypes in acute and chronic infections in Japan.
Journal of medical virology 2008;80(11):1880-4.
2008: Yusuke Kawamura; Kenji Ikeda; Yasuji Arase; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Diabetes mellitus worsens the recurrence rate after potentially curative therapy in patients with hepatocellular carcinoma associated with nonviral hepatitis.
Journal of gastroenterology and hepatology 2008;23(11):1739-46.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Miharu Hirakawa; Satoshi Saito; Kenji Ikeda; Hiromitsu Kumada
Hepatitis C virus enhances incidence of idiopathic pulmonary fibrosis.
World journal of gastroenterology : WJG 2008;14(38):5880-6.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Satoshi Saito; Kenji Ikeda; Hiromitsu Kumada
Potential of laparoscopy in chronic liver disease with hepatitis B and C viruses.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(9):877-85.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy of low-dose intermittent interferon-alpha monotherapy in patients infected with hepatitis C virus genotype 1b who were predicted or failed to respond to pegylated interferon plus ribavirin combination therapy.
Journal of medical virology 2008;80(8):1363-9.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma.
Journal of medical virology 2008;80(8):1354-62.
2008: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Kenji Ikeda; Hiromitsu Kumada
Prolonged-efficacy of bisphosphonate in postmenopausal women with osteoporosis and chronic liver disease.
Journal of medical virology 2008;80(7):1302-7.
2008: Hiromi Yatsuji; Fumitaka Suzuki; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Satomi Iwasaki; Mariko Kobayashi; Hiromitsu Kumada
Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up.
Journal of hepatology 2008;48(6):923-31.
2008: Miharu Hirakawa; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
New ablation procedure for a radiofrequency liver tissue coagulation system using an expandable needle.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(2):214-9.
2008: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological response and hepatocarcinogenesis in lamivudine-resistant hepatitis B virus genotype C patients treated with lamivudine plus adefovir dipivoxil.
Intervirology 2008;51(6):385-93.
2008: Miharu Hirakawa; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hiromi Yatsuji; Hitomi Sezaki; Norio Akuta; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Lipiodol and dye at the site of ablation decreases during RFA.
Intervirology 2008;51(5):362-8.
2008: Hiromi Saneto; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Clinicopathological features, background liver disease, and survival analysis of HCV-positive patients with hepatocellular carcinoma: differences between young and elderly patients.
Journal of gastroenterology 2008;43(12):975-81.
2008: Yoshio Katamura; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Hiromi Yatsuji; Norihiro Nomura; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saito; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Natural human interferon beta plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus and a high viral load.
Internal medicine (Tokyo, Japan) 2008;47(21):1827-34.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
The efficacy of 24-week interferon monotherapy for type C liver cirrhosis in Japanese patients with genotype 1b and low virus load.
Intervirology 2008;51(4):265-9.
2008: Miharu Hirakawa; Kenji Ikeda; Yasuji Arase; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Hepatocarcinogenesis following HCV RNA eradication by interferon in chronic hepatitis patients.
Internal medicine (Tokyo, Japan) 2008;47(19):1637-43.
2008: Kenji Ikeda
Clinical aspects of dementia with argyrophilic grains.
Handbook of clinical neurology 2008;89():549-52.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Yusuke Kawamura; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Suitable treatment period in patients with virological response during combination therapy of peginterferon and ribavirin for chronic hepatitis C.
Internal medicine (Tokyo, Japan) 2008;47(14):1301-7.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
The efficacy of short-term interferon-beta therapy for type C cirrhotic patients with genotype 2a and low virus load.
Internal medicine (Tokyo, Japan) 2008;47(12):1085-90.
2008: Yusuke Kawamura; Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Mariko Kobayashi; Hiromitsu Kumada
The efficacy of short-term interferon-beta therapy for chronic hepatitis C patients with low virus load.
Internal medicine (Tokyo, Japan) 2008;47(5):355-60.
2008: Yasuji Arase; Fumitaka Suzuki; Hitomi Sezaki; Yusuke Kawamura; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hiromi Yatsuji; Miharu Hirakawa; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Efficacy in patients with dose reduction in combination therapy of peginterferon and ribavirin for chronic hepatitis C.
Intervirology 2008;51(1):1-6.
2008: Masahiro Kobayashi; Kenji Ikeda; Yasuji Arase; Yoshiyuki Suzuki; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; N Murashima; Satoshi Saitoh; Takashi Someya; Akihito Tsubota; Hiromitsu Kumada
Inhibitory effect of branched-chain amino acid granules on progression of compensated liver cirrhosis due to hepatitis C virus.
Journal of gastroenterology 2008;43(1):63-70.
2008: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Kenji Ikeda; Mariko Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Changes in viral loads of lamivudine-resistant mutants during entecavir therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(2):132-40.
2007: Yusuke Kawamura; Kenji Ikeda; Yasuji Arase; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Viral elimination reduces incidence of malignant lymphoma in patients with hepatitis C.
The American journal of medicine 2007;120(12):1034-41.
2007: Tomohiro Nishide; Kenji Ikeda; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Yoshiyuki Suzuki; Hiromitsu Kumada
Clinicopathological improvement of non-alcoholic steatohepatitis associated with weight loss during a 14-year follow-up period.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(10):1422-7.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictors of viral kinetics to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Journal of medical virology 2007;79(11):1686-95.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2007;46(5):1357-64.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Interferon-induced prolonged biochemical response reduces hepatocarcinogenesis in hepatitis C virus infection.
Journal of medical virology 2007;79(10):1485-90.
2007: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Hiromi Yatsuji; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Sachiyo Watahiki; Satomi Iwasaki; Yuzo Miyakawa; Hiromitsu Kumada
Loss of hepatitis B surface antigen from the serum of patients with chronic hepatitis treated with lamivudine.
Journal of medical virology 2007;79(10):1472-7.
2007: Eiko Hasegawa; Masahiro Kobayashi; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy and anticarcinogenic activity of interferon for hepatitis C virus-related compensated cirrhosis in patients with genotype 1b low viral load or genotype 2.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(10):793-800.
2007: Hitomi Sezaki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Evaluation of long-term biochemical responses to combination therapy of interferon plus ribavirin in those infected with hepatitis C virus genotype 1b and high baseline viral load.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(10):787-92.
2007: Kenji Ikeda
Glycyrrhizin injection therapy prevents hepatocellular carcinogenesis in patients with interferon-resistant active chronic hepatitis C.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37 Suppl 2():S287-93.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Masahiro Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Comparison of interferon and lamivudine treatment in Japanese patients with HBeAg positive chronic hepatitis B.
Journal of medical virology 2007;79(9):1286-92.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Masahiro Kobayashi; Hiromitsu Kumada
Prolonged-interferon therapy reduces hepatocarcinogenesis in aged-patients with chronic hepatitis C.
Journal of medical virology 2007;79(8):1095-102.
2007: Yuichi Torisu; Kenji Ikeda; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yusuke Kawamura; Hiromi Yatsuji; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Diabetes mellitus increases the risk of hepatocarcinogenesis in patients with alcoholic cirrhosis: A preliminary report.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(7):517-23.
2007: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hiromi Yatsuji; Hitomi Sezaki; Yasuji Arase; Yusuke Kawamura; Tetsuya Hosaka; Mariko Kobayashi; Kenji Ikeda; Masahiro Kobayashi; Sachiyo Watahiki; Hiromitsu Kumada
Selection of a virus strain resistant to entecavir in a nucleoside-naive patient with hepatitis B of genotype H.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;39(2):149-52.
2007: Tomokazu Kawaoka; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Yasuji Arase; Hitomi Sezaki; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Efficacy of lamivudine therapy in elderly patients with chronic hepatitis B infection.
Journal of gastroenterology 2007;42(5):395-401.
2007: Tetsuya Hosaka; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Hitomi Sezaki; Norio Akuta; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Factors associated with the virological response of lamivudine-resistant hepatitis B virus during combination therapy with adefovir dipivoxil plus lamivudine.
Journal of gastroenterology 2007;42(5):368-74.
2007: Masahiro Kobayashi; Kenji Ikeda; Yusuke Kawamura; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Randomized controlled trial for the efficacy of hepatic arterial occlusion during radiofrequency ablation for small hepatocellular carcinoma--direct ablative effects and a long-term outcome.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(3):353-9.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: amino acid substitutions in the core region and low-density lipoprotein cholesterol levels.
Journal of hepatology 2007;46(3):403-10.
2007: Norio Chihara; Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Mariko Kobayashi; Norio Akuta; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Yusuke Kawamura; Masahiro Kobayashi; Sachiyo Watahiki; Kenji Ikeda; Hiromitsu Kumada
Prolonged hepatitis after acute infection with genotype H hepatitis B virus.
Internal medicine (Tokyo, Japan) 2007;46(22):1847-51.
2007: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Yusuke Kawamura; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Hiromi Yatsuji; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Side effects of combination therapy of peginterferon and ribavirin for chronic hepatitis-C.
Internal medicine (Tokyo, Japan) 2007;46(22):1827-32.
2007: Norio Akuta; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Mariko Kobayashi; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Prediction of response to pegylated interferon and ribavirin in hepatitis C by polymorphisms in the viral core protein and very early dynamics of viremia.
Intervirology 2007;50(5):361-8.
2007: Yasuji Arase; Kenji Ikeda; Yoshiyuki Suzuki; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Hiromi Yatsuji; Yusuke Kawamura; Mariko Kobayashi; Hiromitsu Kumada
Serum KL-6 level is elevated in chronic hepatitis C patients with combination therapy of pegylated interferon and ribavirin.
Internal medicine (Tokyo, Japan) 2007;46(15):1155-60.
2007: Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Junko Sato; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Long-term presence of HBV in the sera of chronic hepatitis B patients with HBsAg seroclearance.
Intervirology 2007;50(3):161-5.
2007: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Rikako Koyama; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Long-term outcome after interferon therapy in elderly patients with chronic hepatitis C.
Intervirology 2007;50(1):16-23.
2006: Takashi Someya; Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: a pilot study of patients with hepatitis B virus-related cirrhosis.
Journal of gastroenterology 2006;41(12):1206-13.
2006: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitsu Kumada
Long-term outcome of HBV carriers with negative HBe antigen and normal aminotransferase.
The American journal of medicine 2006;119(11):977-85.
2006: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Satomi Iwasaki; Junko Sato; Sachiyo Watahiki; Yuzo Miyakawa; Hiromitsu Kumada
Response to long-term lamivudine treatment in patients infected with hepatitis B virus genotypes A, B, and C.
Journal of medical virology 2006;78(10):1276-83.
2006: Bart J Veldt; Bettina E Hansen; Kenji Ikeda; Elke Verhey; Hiroshi Suzuki; Solko W Schalm
Long-term clinical outcome and effect of glycyrrhizin in 1093 chronic hepatitis C patients with non-response or relapse to interferon.
Scandinavian journal of gastroenterology 2006;41(9):1087-94.
2006: Shuji Iritani; Mizuho Tohgi; Tetsuaki Arai; Kenji Ikeda
Immunohistochemical study of the serotonergic neuronal system in an animal model of the mood disorder.
Experimental neurology 2006;201(1):60-5.
2006: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hitomi Sezaki; Hiromitsu Kumada; Akihisa Tanaka; Hideharu Harada
Prediction model of hepatocarcinogenesis for patients with hepatitis C virus-related cirrhosis. Validation with internal and external cohorts.
Journal of hepatology 2006;44(6):1089-97.
2006: Kiminori Uka; Fumitaka Suzuki; Norio Akuta; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy of interferon monotherapy in young adult patients with chronic hepatitis C virus infection.
Journal of gastroenterology 2006;41(5):470-5.
2006: Masahiro Kobayashi; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Yuzo Miyakawa; Hiromitsu Kumada
Natural history of compensated cirrhosis in the Child-Pugh class A compared between 490 patients with hepatitis C and 167 with B virus infections.
Journal of medical virology 2006;78(4):459-65.
2006: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Hiromitsu Kumada
A long-term glycyrrhizin injection therapy reduces hepatocellular carcinogenesis rate in patients with interferon-resistant active chronic hepatitis C: a cohort study of 1249 patients.
Digestive diseases and sciences 2006;51(3):603-9.
2006: Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Yasuji Arase; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Junko Satoh; Sachiyo Watahiki; Hiromitsu Kumada
Clinical and virological features of non-breakthrough and severe exacerbation due to lamivudine-resistant hepatitis B virus mutants.
Journal of medical virology 2006;78(3):341-52.
2006: Masahiro Kobayashi; Kenji Ikeda; Tetsuya Hosaka; Hitomi Sezaki; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
Dysplastic nodules frequently develop into hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis.
Cancer 2006;106(3):636-47.
2006: Hitomi Sezaki; Fumitaka Suzuki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Long-term follow-up of HBeAg-positive young adult Japanese patients treated with corticosteroid withdrawal therapy for chronic hepatitis B.
Intervirology 2006;49(6):339-45.
2006: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Yoshiyuki Suzuki; Fumitaka Suzuki; Norio Akuta; Yasuji Arase; Hiromitsu Kumada
Origin of neovascular structure in an early stage of hepatocellular carcinoma: study of alpha-smooth muscle actin immunohistochemistry in serial thin sections of surgically resected cancer.
Journal of gastroenterology and hepatology 2006;21(1 Pt 1):183-90.
2006: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Long-term outcome after hepatitis B surface antigen seroclearance in patients with chronic hepatitis B.
The American journal of medicine 2006;119(1):71.e9-16.
2006: Rikako Koyama; Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Efficacy of interferon therapy in elderly patients with chronic hepatitis C.
Intervirology 2006;49(3):121-6.
2006: Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Tetsuya Hosaka; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Junko Sato; Sachiyo Watabiki; Yuzo Miyakawa; Hiromitsu Kumada
Virological outcomes in patients infected chronically with hepatitis B virus genotype A in comparison with genotypes B and C.
Journal of medical virology 2006;78(1):60-7.
2006: Norio Akuta; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Sachiyo Watahiki; Junko Sato; Masahiro Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load.
Journal of medical virology 2006;78(1):83-90.
2006: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Anticarcinogenic impact of interferon on patients with chronic hepatitis C: a large-scale long-term study in a single center.
Intervirology 2006;49(1-2):82-90.
2005: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Yoshiyuki Suzuki; Fumitaka Suzuki; Norio Akuta; Yasuji Arase; Hiromitsu Kumada; Masamichi Matsuda; Masaji Hashimoto; Goro Watanabe
Cost-effectiveness of radiofrequency ablation and surgical therapy for small hepatocellular carcinoma of 3cm or less in diameter.
Hepatology research : the official journal of the Japan Society of Hepatology 2005;33(3):241-9.
2005: Yusuke Kawamura; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Determinants of serum ALT normalization after phlebotomy in patients with chronic hepatitis C infection.
Journal of gastroenterology 2005;40(9):901-6.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Long-term follow-up of interferon monotherapy in 454 consecutive naive patients infected with hepatitis C virus: multi-course interferon therapy may reduce the risk of hepatocellular carcinoma and increase survival.
Scandinavian journal of gastroenterology 2005;40(6):688-96.
2005: Yoshiyuki Suzuki; Masahiro Kobayashi; Kenji Ikeda; Fumitaka Suzuki; Yasuji Arfase; Norio Akuta; Tetsuya Hosaka; Satoshi Saitoh; Mariko Kobayashi; Takashi Someya; Marie Matsuda; Junko Sato; Sachiyo Watabiki; Yuzo Miyakawa; Hiromitsu Kumada
Persistence of acute infection with hepatitis B virus genotype A and treatment in Japan.
Journal of medical virology 2005;76(1):33-9.
2005: Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Akihito Tsubota; Kenji Ikeda; Yasuji Arase; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Tetsuya Hosaka; Takashi Someya; Marie Matsuda; Junko Sato; Yuzo Miyakawa; Hiromitsu Kumada
Virological differences between patients infected with subtypes Ba and Bj of hepatitis B virus genotype B.
Journal of gastroenterology and hepatology 2005;20(4):570-6.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Masahiro Kobayashi; Hiromitsu Kumada
Hepatocyte steatosis is an important predictor of response to interferon (IFN) monotherapy in Japanese patients infected with HCV genotype 2a: Virological features of IFN-resistant cases with hepatocyte steatosis.
Journal of medical virology 2005;75(4):550-8.
2005: Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
Favorable efficacy of long-term lamivudine therapy in patients with chronic hepatitis B: an 8-year follow-up study.
Journal of medical virology 2005;75(4):491-8.
2005: Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Fumitaka Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Lamivudine monotherapy for spontaneous severe acute exacerbation of chronic hepatitis B.
Journal of gastroenterology and hepatology 2005;20(3):426-32.
2005: Nobuhiko Hiraga; Fumitaka Suzuki; Norio Akuta; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Marie Matsuda; Sachiyo Watabiki; Junko Satoh; Hiromitsu Kumada
Clinical and virological characteristics of untreated patients with chronic hepatitis C who develop serum alanine aminotransferase flare-up.
Journal of medical virology 2005;75(2):240-8.
2005: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Usefulness of the serum KL-6 assay in patients with hepatitis C virus.
Intervirology 2005;48(6):400-4.
2005: Norio Akuta; Fumitaka Suzuki; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Sachiyo Watahiki; Junko Sato; Marie Matsuda; Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.
Intervirology 2005;48(6):372-80.
2005: Kenji Ikeda; Hiromitsu Kumada
Locoregional therapy for hepatocellular carcinoma.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation 2005;26(1):4-12.
2005: Norio Akuta; Fumitaka Suzuki; Mariko Kobayashi; Marie Matsuda; Junko Sato; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological and biochemical relapse after discontinuation of lamivudine monotherapy for chronic hepatitis B in Japan: comparison with breakthrough hepatitis during long-term treatment.
Intervirology 2005;48(2-3):174-82.
2005: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Hiromitsu Kumada
Significance of serum ribavirin concentration in combination therapy of interferon and ribavirin for chronic hepatitis C.
Intervirology 2005;48(2-3):138-44.
2005: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Takashi Someya; Tetsuya Hosaka; Satoshi Saitoh; Hitomi Sezaki; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Hepatitis B virus-related hepatocellular carcinogenesis and its prevention.
Intervirology 2005;48(1):29-38.
2005: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Norio Akuta; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Hiromitsu Kumada
Significance of hepatitis B virus DNA clearance and early prediction of hepatocellular carcinogenesis in patients with cirrhosis undergoing interferon therapy: long-term follow up of a pilot study.
Journal of gastroenterology and hepatology 2005;20(1):95-102.
2005: Akihito Tsubota; Yasuji Arase; Takashi Someya; Yoshiyuki Suzuki; Fumitaka Suzuki; Satoshi Saitoh; Kenji Ikeda; Norio Akuta; Tetsuya Hosaka; Masahiro Kobayashi; Hiromitsu Kumada
Early viral kinetics and treatment outcome in combination of high-dose interferon induction vs. pegylated interferon plus ribavirin for naive patients infected with hepatitis C virus of genotype 1b and high viral load.
Journal of medical virology 2005;75(1):27-34.
2004: Yasuji Arase; Kenji Ikeda; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Masahiro Kobayashi; Hiromitsu Kumada
Adequate timing of ribavirin reduction in patients with hemolysis during combination therapy of interferon and ribavirin for chronic hepatitis C.
Journal of gastroenterology 2004;39(11):1090-4.
2004: Hiromi Ooga; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Junko Satoh; Hiromitsu Kumada
Efficacy of lamivudine treatment in Japanese patients with hepatitis B virus-related cirrhosis.
Journal of gastroenterology 2004;39(11):1078-84.
2004: Fumitaka Suzuki; Yasuji Arase; Norio Akuta; Akihito Tsubota; Yoshiyuki Suzuki; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Marie Matsuda; Junko Satoh; Hiromitsu Kumada
Efficacy of 6-month interferon therapy in chronic hepatitis B virus infection in Japan.
Journal of gastroenterology 2004;39(10):969-74.
2004: Marie Matsuda; Fumitaka Suzuki; Yoshiyuki Suzuki; Akihito Tsubota; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Junko Satoh; Masahiro Kobayashi; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine.
Journal of medical virology 2004;74(2):361-6.
2004: Mariko Kobayashi; Fumitaka Suzuki; Yasuji Arase; Norio Akuta; Yoshiyuki Suzuki; Tetsuya Hosaka; Satoshi Saitoh; Masahiro Kobayashi; Akihito Tsubota; Takashi Someya; Kenji Ikeda; Marie Matsuda; Junko Sato; Hiromitsu Kumada
Infection with hepatitis B virus genotype A in Tokyo, Japan during 1976 through 2001.
Journal of gastroenterology 2004;39(9):844-50.
2004: Kenji Ikeda
[Current status of treatment for HBV-related cirrhosis].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 8():358-62.
2004: Satoshi Mamori; Fumitaka Suzuki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Interferon monotherapy for patients with chronic hepatitis C and normal serum aminotransferase levels at commencement of treatment.
Journal of gastroenterology 2004;39(8):776-82.
2004: Shintaro Takaki; Akihito Tsubota; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Factors contributing to ribavirin dose reduction due to anemia during interferon alfa2b and ribavirin combination therapy for chronic hepatitis C.
Journal of gastroenterology 2004;39(7):668-73.
2004: Yoshiyuki Suzuki; Masahiro Kobayashi; Tetsuya Hosaka; Takashi Someya; Norio Akuta; Mariko Kobayashi; Fumitaka Suzuki; Akihito Tsubota; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Marie Matsuda; Junko Sato; Yuzo Miyakawa; Hiromitsu Kumada
Peripheral CD8+/CD25+ lymphocytes may be implicated in hepatocellular injuries in patients with acute-onset autoimmune hepatitis.
Journal of gastroenterology 2004;39(7):649-53.
2004: Hitomi Sezaki; Mariko Kobayashi; Tetsuya Hosaka; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Kimiko Takagi; Junko Sato; Hiromitsu Kumada
Hepatocellular carcinoma in noncirrhotic young adult patients with chronic hepatitis B viral infection.
Journal of gastroenterology 2004;39(6):550-6.
2004: Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Satoshi Saitoh; Akihito Tsubota; Fumitaka Suzuki; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Yuzo Miyakawa; Hiromitsu Kumada
Clinical and pathological characteristics of the autoimmune hepatitis and primary biliary cirrhosis overlap syndrome.
Journal of gastroenterology and hepatology 2004;19(6):699-706.
2004: Fumitaka Suzuki; Yasuji Arase; Yoshiyuki Suzuki; Akihito Tsubota; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; M Kobayashi; M Matsuda; K Takagi; J Satoh; Hiromitsu Kumada
Single nucleotide polymorphism of the MxA gene promoter influences the response to interferon monotherapy in patients with hepatitis C viral infection.
Journal of viral hepatitis 2004;11(3):271-6.
2004: Akihito Tsubota; Yasuji Arase; Fumitaka Suzuki; Mariko Kobayashi; Marie Matsuda; Junko Sato; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Severe acute exacerbation of liver disease may reduce or delay emergence of YMDD motif mutants in long-term lamivudine therapy for hepatitis B e antigen-positive chronic hepatitis B.
Journal of medical virology 2004;73(1):7-12.
2004: Norio Akuta; Fumitaka Suzuki; Mariko Kobayashi; Akihito Tsubota; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Effect of acute self-limited hepatitis C virus (HCV) superinfection on hepatitis B virus (HBV)-related cirrhosis. Virological features of HBV-HCV dual infection.
Digestive diseases and sciences 2004;49(2):281-8.
2004: Tetsuya Hosaka; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Takashi Someya; Hitomi Sezaki; Norio Akuta; Akihito Tsubota; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.
Intervirology 2004;47(6):362-9.
2004: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Fumitaka Suzuki; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Hitomi Sezaki; Mariko Kobayashi; Hiromitsu Kumada
Interferon therapy for 2 years or longer reduces the incidence of hepatocarcinogenesis in patients with chronic hepatitis C viral infection.
Intervirology 2004;47(6):355-61.
2004: Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Fumitaka Suzuki; Tetsuya Hosaka; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Benefit of lamivudine therapy and factors associated with clinical outcome in spontaneous severe acute exacerbation of chronic hepatitis B virus infection.
Intervirology 2004;47(6):335-41.
2004: Kenji Nobuhara; Gaku Okugawa; Tomohisa Minami; Katsunori Takase; Tsunetaka Yoshida; Takami Yagyu; A Tajika; Tatsuya Sugimoto; Chiharu Tamagaki; Kenji Ikeda; Satoshi Sawada; Toshihiko Kinoshita
Effects of electroconvulsive therapy on frontal white matter in late-life depression: a diffusion tensor imaging study.
Neuropsychobiology 2004;50(1):48-53.
2004: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Masahiro Kobayashi; Hiromitsu Kumada
Efficacy of interferon retreatment after relapse for chronic hepatitis C patients with biochemical response after first interferon therapy.
Journal of gastroenterology 2004;39(5):455-60.
2004: Masahiro Kobayashi; Kenji Ikeda; Tetsuya Hosaka; Takashi Someya; Satoshi Saitoh; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Akihito Tsubota; Yasuji Arase; Hiromitsu Kumada
Successful control of ruptured hepatocellular carcinoma with radiofrequency ablation.
Journal of gastroenterology 2004;39(2):192-3.
2004: Akihito Tsubota; Yasuji Arase; Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
High-dose interferon alpha-2b induction therapy in combination with ribavirin for Japanese patients infected with hepatitis C virus genotype 1b with a high baseline viral load.
Journal of gastroenterology 2004;39(2):155-61.
2004: Yasuji Arase; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Mariko Kobayashi; Norio Akuta; Takashi Someya; Tetsuya Hosaka; Masahiro Kobayashi; Hitomi Sezaki; Kenji Ikeda; Hiromitsu Kumada
Sustained negativity for HCV-RNA over 24 or more months by long-term interferon therapy correlates with eradication of HCV in patients with hepatitis C virus genotype 1b and high viral load.
Intervirology 2004;47(1):19-25.
2004: M Kobayashi; Y Arase; Kenji Ikeda; A Tsubota; Y Suzuki; S Saitoh; M Kobayashi; F Suzuki; N Akuta; T Hosaka; T Someya; M Matsuda; J Sato; Y Miyakawa; H Kumada
Wild-type precore and core promoter sequences in patients with acute self-limited or chronic hepatitis B.
Scandinavian journal of gastroenterology 2004;39(1):53-9.
2004: Marie Matsuda; Fumitaka Suzuki; Yoshiyuki Suzuki; Akihito Tsubota; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Junko Satoh; Kimiko Takagi; Mariko Kobayashi; Kenji Ikeda; Hiromitsu Kumada
Low rate of YMDD motif mutations in polymerase gene of hepatitis B virus in chronically infected patients not treated with lamivudine.
Journal of gastroenterology 2004;39(1):34-40.
2003: Norio Akuta; Fumitaka Suzuki; Mariko Kobayashi; Marie Matsuda; Junko Sato; Kimiko Takagi; Akihito Tsubota; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Virological and biochemical relapse according to YMDD motif mutant type during long-term lamivudine monotherapy.
Journal of medical virology 2003;71(4):504-10.
2003: Yasuji Arase; Akihito Tsubota; Yoshiyuki Suzuki; Fumitaka Suzuki; Masahiro Kobayashi; Takashi Someya; Norio Akuta; Tetsuya Hosaka; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Hiromitsu Kumada
A pilot study of thymosin alpha1 therapy for chronic hepatitis B patients.
Internal medicine (Tokyo, Japan) 2003;42(10):941-6.
2003: Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Interferon-alpha for reinfection with hepatitis C virus in two patients with chronic hepatitis C who had responded to previous therapies.
Digestive diseases and sciences 2003;48(8):1654-7.
2003: Junko Tanaka; Hiromitsu Kumada; Kenji Ikeda; Kazuaki Chayama; Masaaki Mizui; Kunihiko Hino; Keiko Katayama; Junko Kumagai; Yutaka Komiya; Yuzo Miyakawa; Hiroshi Yoshizawa
Natural histories of hepatitis C virus infection in men and women simulated by the Markov model.
Journal of medical virology 2003;70(3):378-86.
2003: Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Mariko Kobayashi; Marie Matsuda; Junko Satoh; Kimiko Takagi; Hiromitsu Kumada
HBe antigen loss during lamivudine therapy is not caused by mutations in precore and core promoter genes in patients with chronic hepatitis B.
Journal of medical virology 2003;70(3):355-60.
2003: Norio Akuta; Fumitaka Suzuki; Mariko Kobayashi; Akihito Tsubota; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
The influence of hepatitis B virus genotype on the development of lamivudine resistance during long-term treatment.
Journal of hepatology 2003;38(3):315-21.
2003: Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Association of amino acid substitution pattern in nonstructural protein 5A of hepatitis C virus genotype2a low viral load and response to interferon monotherapy.
Journal of medical virology 2003;69(3):376-83.
2003: Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Recurrence rate and prognosis of patients with hepatocellular carcinoma that developed after elimination of hepatitis C virus RNA by interferon therapy. A closed cohort study including matched control patients.
Oncology 2003;65(3):204-10.
2003: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Satoshi Saitoh; Takashi Someya; Tetsuya Hosaka; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Norio Akuta; Hiromitsu Kumada
Significance of multicentric cancer recurrence after potentially curative ablation of hepatocellular carcinoma: a longterm cohort study of 892 patients with viral cirrhosis.
Journal of gastroenterology 2003;38(9):865-76.
2003: Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Tetsuya Hosaka; Satoshi Saitoh; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Marie Matsuda; Junko Sato; Hiromitsu Kumada
Clinical features of hepatitis B virus genotype A in Japanese patients.
Journal of gastroenterology 2003;38(7):656-62.
2003: Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Mariko Kobayashi; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Marie Matsuda; Junko Satoh; Kimiko Takagi; Hiromitsu Kumada
Efficacy of lamivudine therapy and factors associated with emergence of resistance in chronic hepatitis B virus infection in Japan.
Intervirology 2003;46(3):182-9.
2003: Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Satoshi Saitoh; Akihito Tsubota; Fumitaka Suzuki; Masahiro Kobayashi; Norio Akuta; Takashi Someya; Yuzo Miyakawa; Hiromitsu Kumada
Histological improvements after a three-year lamivudine therapy in patients with chronic hepatitis B in whom YMDD mutants did not or did develop.
Intervirology 2003;46(3):164-70.
2003: Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Tetsuya Hosaka; Takashi Someya; Marie Matsuda; Junko Sato; Kimiko Takagi; Yuzo Miyakawa; Hiromitsu Kumada
Precore wild-type hepatitis B virus with G1896 in the resolution of persistent hepatitis B virus infection.
Intervirology 2003;46(3):157-63.
2003: Hitomi Sezaki; Yasuji Arase; Akihito Tsubota; Yoshiyuki Suzuki; Masahiro Kobayashi; Satoshi Saitoh; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Kenji Ikeda; Hiromitsu Kumada
Type C-chronic hepatitis patients who had autoimmune phenomenon and developed jaundice during interferon therapy.
Journal of gastroenterology 2003;38(5):493-500.
2003: Kenji Ikeda; Yasuji Arase; Masahiro Kobayashi; Takashi Someya; Satoshi Saitoh; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Norio Akuta; Hiromitsu Kumada
Consistently low hepatitis B virus DNA saves patients from hepatocellular carcinogenesis in HBV-related cirrhosis. A nested case-control study using 96 untreated patients.
Intervirology 2003;46(2):96-104.
2003: Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Mariko Kobayashi; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Hiromitsu Kumada
Efficacy of prolonged interferon therapy for patients with chronic hepatitis C with HCV-genotype 1b and high virus load.
Journal of gastroenterology 2003;38(2):158-63.
2003: Norio Akuta; Akihito Tsubota; Fumitaka Suzuki; Yoshiyuki Suzuki; Tetsuya Hosaka; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Long-term prognosis by lamivudine monotherapy for severe acute exacerbation in chronic hepatitis B infection: emergence of YMDD motif mutant and risk of breakthrough hepatitis -- an open-cohort study.
Journal of hepatology 2003;38(1):91-7.
2002: Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Efficacy of interferon monotherapy to 394 consecutive naive cases infected with hepatitis C virus genotype 2a in Japan: therapy efficacy as consequence of tripartite interaction of viral, host and interferon treatment-related factors.
Journal of hepatology 2002;37(6):831-6.
2002: Fumitaka Suzuki; Yoshiyuki Suzuki; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Mutations of polymerase, precore and core promoter gene in hepatitis B virus during 5-year lamivudine therapy.
Journal of hepatology 2002;37(6):824-30.
2002: Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Marie Matsuda; Junko Sato; Kimiko Takagi; Yuzo Miyakawa; Hiromitsu Kumada
Viral genotypes and response to interferon in patients with acute prolonged hepatitis B virus infection of adulthood in Japan.
Journal of medical virology 2002;68(4):522-8.
2002: Hiroshi Nakase; Kazuichi Okazaki; Masaya Ohana; Kenji Ikeda; Kazushige Uchida; Suguru Uose; Toshiyuki Itoh; Masahiro Iwano; Norihiko Watanabe; Shujiro Yazumi; Chiharu Kawanami; F Inoue; Tsutomu Chiba
The possible involvement of micro-organisms other than Helicobacter pylori in the development of rectal MALT lymphoma in H. pylori-negative patients.
Endoscopy 2002;34(4):343-6.
2002: Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Yoshiyuki Suzuki; Takashi Someya; Masahiro Kobayashi; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Long-term clinical remission induced by corticosteroid withdrawal therapy (CSWT) in patients with chronic hepatitis B infection: a prospective randomized controlled trial--CSWT with and without follow-up interferon-alpha therapy.
Digestive diseases and sciences 2002;47(2):405-14.
2002: Fumitaka Suzuki; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Yuzo Miyakawa; Hiromitsu Kumada
Interferon for treatment of breakthrough infection with hepatitis B virus mutants developing during long-term lamivudine therapy.
Journal of gastroenterology 2002;37(11):922-7.
2002: Masahiro Kobayashi; Kenji Ikeda; Takashi Someya; Norio Akuta; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Hiromitsu Kumada
Stepwise hook extension technique for radiofrequency ablation therapy of hepatocellular carcinoma.
Oncology 2002;63(2):139-44.
2002: Kenji Ikeda; Masahiro Kobayashi; Takashi Someya; Satoshi Saitoh; Akihito Tsubota; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Yasuji Arase; Hiromitsu Kumada
Influence of hepatitis C virus subtype on hepatocellular carcinogenesis: a multivariate analysis of a retrospective cohort of 593 patients with cirrhosis.
Intervirology 2002;45(2):71-8.
2002: Akihito Tsubota; Norio Akuta; Fumitaka Suzuki; Yoshiyuki Suzuki; Takahi Someya; Masahiro Kobayashi; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; Hiromitsu Kumada
Viral dynamics and pharmacokinetics in combined interferon alfa-2b and ribavirin therapy for patients infected with hepatitis C virus of genotype 1b and high pretreatment viral load.
Intervirology 2002;45(1):33-42.
2002: Mariko Kobayashi; Yasuji Arase; Kenji Ikeda; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; Fumitaka Suzuki; Norio Akuta; Takashi Someya; Marie Matsuda; Junko Sato; Hiromitsu Kumada
Clinical characteristics of patients infected with hepatitis B virus genotypes A, B, and C.
Journal of gastroenterology 2002;37(1):35-9.
2001: Kenji Ikeda
[Prevention of hepatocellular carcinogenesis by interferon].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 6():755-63.
2001: Akihito Tsubota; Yasuji Arase; F Ren; H Tanaka; Kenji Ikeda; Hiromitsu Kumada
Genotype may correlate with liver carcinogenesis and tumor characteristics in cirrhotic patients infected with hepatitis B virus subtype adw.
Journal of medical virology 2001;65(2):257-65.
2001: Kenji Ikeda
[Less invasive medical therapy for hepatocellular carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 2001;28(8):1083-9.
2001: Kenji Ikeda; Yasuji Arase; Hiromitsu Kumada
[Hepatocellular carcinogenesis and prognosis of elderly patients with chronic hepatitis type C].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(7):1338-44.
2001: N Murachima; Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Kazuaki Chayama; Akihito Tsubota; Yoshiyuki Suzuki; Fumitaka Suzuki; Yasuji Arase; Hiromitsu Kumada
Incidence of the appearance of the red color sign on esophageal varices and its predictive factors: long-term observations of 359 patients with cirrhosis.
Journal of gastroenterology 2001;36(6):368-74.
2001: K Chayama; F Suzuki; A Tsubota; N Akuta; T Someya; M Kobayashi; Y Arase; S Saitoh; Y Suzuki; Kenji Ikeda; H Kumada
Evaluation of quantitative measurements of hepatitis C virus RNA to predict sustained response to interferon by genotype.
Journal of virological methods 2001;95(1-2):33-45.
2001: N Akuta; K Chayama; F Suzuki; T Someya; M Kobayashi; A Tsubota; Y Suzuki; S Saitoh; Yasuji Arase; Kenji Ikeda; H Kumada
Risk factors of hepatitis C virus-related liver cirrhosis in young adults: positive family history of liver disease and transporter associated with antigen processing 2(TAP2)*0201 Allele.
Journal of medical virology 2001;64(2):109-16.
2001: Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study.
Journal of gastroenterology and hepatology 2001;16(4):406-15.
2001: Fumitaka Suzuki; Kazuaki Chayama; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Twice-daily administration of interferon-beta for chronic hepatitis C is not superior to a once-daily regimen.
Journal of gastroenterology 2001;36(4):242-7.
2001: Akihito Tsubota; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Kazuaki Chayama; N Murashima; Kenji Ikeda; M Kobayashi; Hiromitsu Kumada
Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: a preliminary study.
The American journal of gastroenterology 2001;96(2):557-62.
2001: Takashi Someya; Yoshiyuki Suzuki; Yasuji Arase; Masahiro Kobayashi; Fumitaka Suzuki; Akihito Tsubota; Satoshi Saitoh; Kazuaki Chayama; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Interferon therapy for flare-up of hepatitis B virus infection after emergence of lamivudine-induced YMDD motif mutant.
Journal of gastroenterology 2001;36(2):133-6.
2001: Fumitaka Suzuki; Kazuaki Chayama; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Pathogenic significance and organic virus levels in patients infected with TT virus.
Intervirology 2001;44(5):291-7.
2000: Kazuaki Chayama; Fumitaka Suzuki; Akihito Tsubota; Masahiro Kobayashi; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; N Takahashi; M Kinoshita; Hiromitsu Kumada
Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy.
Hepatology (Baltimore, Md.) 2000;32(5):1138-44.
2000: S Hosoda; H Takimura; M Shibayama; H Kanamura; Kenji Ikeda; H Kumada
Psychiatric symptoms related to interferon therapy for chronic hepatitis C: clinical features and prognosis.
Psychiatry and clinical neurosciences 2000;54(5):565-72.
2000: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer.
Hepatology (Baltimore, Md.) 2000;32(2):228-32.
2000: Masahiro Kobayashi; Kenji Ikeda; Satoshi Saitoh; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
Incidence of primary cholangiocellular carcinoma of the liver in japanese patients with hepatitis C virus-related cirrhosis.
Cancer 2000;88(11):2471-7.
2000: M Kobyashi; Kazuaki Chayama; Yasuji Arase; Akihito Tsubota; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; N Murashima; Kenji Ikeda; M Hagiwara; R Hashimoto; M Nakagawa; M Matsuda; Hiromitsu Kumada
Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance.
Journal of gastroenterology 2000;35(10):753-7.
2000: Masahiro Kobayashi; Kenji Ikeda; Norio Akuta; Takashi Someya; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama; Hiromitsu Kumada
Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C.
Intervirology 2000;43(3):174-9.
2000: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Fumitaka Suzuki; Hiromitsu Kumada
Increased response rate to interferon therapy after a second course in hepatitis C patients who show relapse after the initial course.
Journal of gastroenterology 2000;35(8):607-12.
2000: Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Hepatic vascular side effects of styrene maleic acid neocarzinostatin in the treatment of hepatocellular carcinoma.
Journal of gastroenterology 2000;35(5):353-60.
2000: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Fumitaka Suzuki; Hiromitsu Kumada
Fluctuation patterns of HCV-RNA serum level in patients with chronic hepatitis C.
Journal of gastroenterology 2000;35(3):221-5.
1999: Y Hoshida; Kenji Ikeda; Masahiro Kobayashi; Yoshiyuki Suzuki; Akihito Tsubota; Satoshi Saitoh; Yasuji Arase; M Kobayashi; N Murashima; K Chayama; Hiromitsu Kumada
Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis.
Journal of hepatology 1999;31(5):860-6.
1999: Yasuji Arase; Kenji Ikeda; N Murashima; Kazuaki Chayama; Akihito Tsubota; I Koida; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Hiromitsu Kumada
Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B.
The American journal of gastroenterology 1999;94(11):3304-9.
1999: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; I Nakamura; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Clinical and virological features of chronic hepatitis C carriers with normal alanine aminotransferase levels despite positive serum HCV-RNA after interferon therapy.
Journal of gastroenterology 1999;34(5):594-9.
1999: Akihito Tsubota; Hiromitsu Kumada; Yasuji Arase; Kazuaki Chayama; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Yoshiyuki Suzuki; N Murashima
Combined ursodeoxycholic acid and glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients.
European journal of gastroenterology & hepatology 1999;11(10):1077-83.
1999: Y Hoshida; S Saitoh; N Murashima; A Ogawa; Yasuji Arase; M Kobayashi; Y Suzuki; A Tsubota; Kazuaki Chayama; Kenji Ikeda; H Kumada
Vaginal variceal hemorrhage in a patient with primary biliary cirrhosis: a case successfully treated by balloon-occluded retrograde transvenous obliteration.
The American journal of gastroenterology 1999;94(10):3081-3.
1999: K Ogawa; M Kishi; Teruyuki Kurihara; Kenji Ikeda; M Kinoshita
Multiple sclerosis with extensive lesions left hemiplegia, mental dysfunction and retrobulbar neuritis.
Psychiatry and clinical neurosciences 1999;53(4):485-90.
1999: M Kobayashi; K Chayama; Y Arase; A Tsubota; S Saitoh; Y Suzuki; M Kobayashi; Kenji Ikeda; M Matsuda; H Koike; M Hashimoto; H Kumada
Enzyme-linked immunosorbent assay to detect hepatitis C virus serological groups 1 to 6.
Journal of gastroenterology 1999;34(4):505-9.
1999: M Hashimoto; Kazuaki Chayama; Masahiro Kobayashi; Akihito Tsubota; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; Kenji Ikeda; M Matsuda; H Koike; M Kobayashi; H Handa; Hiromitsu Kumada
Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region.
Journal of medical virology 1999;58(3):247-55.
1999: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Efficacy and changes of the nonstructural 5A GENE by prolonged interferon therapy for patients with hepatitis C virus genotype 1b and a high level of serum HCV-RNA.
Internal medicine (Tokyo, Japan) 1999;38(6):461-6.
1999: Yoshiyuki Suzuki; Hiromitsu Kumada; Kenji Ikeda; K Chayama; Yasuji Arase; Satoshi Saitoh; Akihito Tsubota; Masahiro Kobayashi; M Koike; N Ogawa; K Tanikawa
Histological changes in liver biopsies after one year of lamivudine treatment in patients with chronic hepatitis B infection.
Journal of hepatology 1999;30(5):743-8.
1999: Shuji Iritani; Noriomi Kuroki; Kenji Ikeda; H Kazamatsuri
Calbindin immunoreactivity in the hippocampal formation and neocortex of schizophrenics.
Progress in neuro-psychopharmacology & biological psychiatry 1999;23(3):409-21.
1999: Masahiro Kobayashi; Kazuaki Chayama; Yasuji Arase; M Kobayashi; Akihito Tsubota; Yoshiyuki Suzuki; I Koida; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Koike; M Hashimoto; M Kobayashi; Hiromitsu Kumada
Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma.
Journal of gastroenterology and hepatology 1999;14(4):358-63.
1999: Kenji Ikeda; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Nakamura; N Murashima; Hiromitsu Kumada; M Kawanishi
Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis.
Hepatology (Baltimore, Md.) 1999;29(4):1124-30.
1999: M Tagami; K Yamagata; Kenji Ikeda; H Fujino; Y Nara; K Nakagawa; A Kubota; F Numano; Y Yamori
Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(1):23-9.
1999: Kazuaki Chayama; Masahiro Kobayashi; Akihito Tsubota; M Kobayashi; Yasuji Arase; Yoshiyuki Suzuki; Satoshi Saitoh; N Murashima; Kenji Ikeda; K Okamoto; M Hashimoto; M Matsuda; H Koike; M Kobayashi; Hiromitsu Kumada
Susceptibility of TT virus to interferon therapy.
The Journal of general virology 1999;80 ( Pt 3)():631-4.
1999: M Kobayashi; K Chayama; Y Arase; A Tsubota; S Saitoh; Y Suzuki; M Kobayashi; M Kobayashi; Kenji Ikeda; M Matsuda; H Koike; M Hashimoto; H Kumada
Predictive value of different hepatitis C serological assays in the treatment of chronic hepatitis C with interferon alpha.
Journal of gastroenterology 1999;34(1):94-9.
1999: Y Hoshida; Kenji Ikeda; S Saito; Masahiro Kobayashi; M Kobayashi; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
[The efficacy and prognosis of transcatheter chemoembolization for hepatocellular carcinoma in the elderly].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1999;96(2):142-6.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Koida; M Kobayashi; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle actin in small hepatocellular carcinoma.
Journal of gastroenterology and hepatology 1998;13(12):1266-73.
1998: Akihito Tsubota; Hiromitsu Kumada; K Takaki; Kazuaki Chayama; Masahiro Kobayashi; M Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; N Murashima; Kenji Ikeda
Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers.
Journal of medical virology 1998;56(4):287-93.
1998: A Orimo; Satoshi Inoue; Kenji Ikeda; M Sato; A Kato; N Tominaga; M Suzuki; T Noda; M Watanabe; M Muramatsu
Molecular cloning, localization, and developmental expression of mouse brain finger protein (Bfp)/ZNF179: distribution of bfp mRNA partially coincides with the affected areas of Smith-Magenis syndrome.
Genomics 1998;54(1):59-69.
1998: Yasuji Arase; Kenji Ikeda; N Murashima; Kazuaki Chayama; Akihito Tsubota; I Koida; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Glomerulonephritis in autopsy cases with hepatitis C virus infection.
Internal medicine (Tokyo, Japan) 1998;37(10):836-40.
1998: M Menjo; Kenji Ikeda; M Nakanishi
Regulation of G1 cyclin-dependent kinases in liver regeneration.
Journal of gastroenterology and hepatology 1998;13 Suppl():S100-5.
1998: Masahiro Kobayashi; Kazuaki Chayama; M Fukuda; Akihito Tsubota; Yoshiyuki Suzuki; Yasuji Arase; I Koida; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Koike; M Hashimoto; Y Miyano; M Kobayashi; Hiromitsu Kumada
Biochemical and histological features of hepatitis G virus infection.
Journal of gastroenterology and hepatology 1998;13(8):767-72.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Koida; Yasuji Arase; M Fukuda; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients.
Journal of hepatology 1998;28(6):930-8.
1998: Kazuaki Chayama; Yoshiyuki Suzuki; Masahiro Kobayashi; M Kobayashi; Akihito Tsubota; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy.
Hepatology (Baltimore, Md.) 1998;27(6):1711-6.
1998: Kenji Ikeda; Hiromitsu Kumada; S Saitoh; Y Suzuki; M Kobayashi; Akihito Tsubota; I Koida; M Fukuda; Yasuji Arase; K Chayama; N Murashima; T Tango
A randomized controlled trial of interferon-alpha in patients with cirrhosis caused by 2a/2b genotype hepatitis C virus.
Journal of hepatology 1998;28(5):910-1.
1998: M Fukuda; Kazuaki Chayama; Akihito Tsubota; Masahiro Kobayashi; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon.
Journal of gastroenterology and hepatology 1998;13(4):412-8.
1998: Masahiro Kobayashi; Hiromitsu Kumada; Yasuji Arase; Kazuaki Chayama; M Kobayashi; Akihito Tsubota; I Koida; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; Y Miyano; K Mizoshita; M Matsuda; H Koike; M Hashimoto
Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype.
Journal of gastroenterology 1998;33(2):223-8.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; M Fukuda; I Koida; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus: a pilot study.
Cancer 1998;82(5):827-35.
1998: Kenji Ikeda; S Saitoh; H Kumada
[Effect of arterial administration of a high molecular weight anti-tumor agent styrene maleic acid neocarzinostatin for multiple small liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25 Suppl 1():19-23.
1997: Toshio Yamada; Hiroto Miwa; Kenji Ikeda; K Ohta; Ryozo Iwazaki; Akihisa Miyazaki; Sumio Watanabe; Hiroshi Hashimoto; Shunji Futagawa; Nobuhiro Sato
Polyarteritis nodosa associated with gastric carcinoma and hepatitis B virus infection.
Journal of clinical gastroenterology 1997;25(3):535-7.
1997: K Chayama; M Kobayashi; Kenji Ikeda; H Kumada
Effect of interferon therapy on viral titers in patients with chronic hepatitis C who are positive for hepatitis GB virus C.
Journal of hepatology 1997;27(4):769-70.
1997: Toshiyuki Matsui; S Hatakeyama; Kenji Ikeda; Tsuneyoshi Yao; K Takenaka; Toshihiro Sakurai
Long-term outcome of endoscopic balloon dilation in obstructive gastroduodenal Crohn's disease.
Endoscopy 1997;29(7):640-5.
1997: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Masahiro Kobayashi; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostatin, for multiple small liver cancer--a pilot study.
Journal of gastroenterology 1997;32(4):513-20.
1997: Akihito Tsubota; Hiromitsu Kumada; Kazuaki Chayama; Yasuji Arase; Satoshi Saitoh; I Koida; Yoshiyuki Suzuki; Masahiro Kobayashi; N Murashima; Kenji Ikeda
Time course of histological changes in patients with a sustained biochemical and virological response to interferon-alpha therapy for chronic hepatitis C virus infection.
Journal of hepatology 1997;27(1):49-55.
1997: T Horimoto; Hideyuki Takahashi; M Sakaguchi; K Horikoshi; Shuji Iritani; H Kazamatsuri; Kenji Ikeda; M Tashiro
A reverse-type sandwich enzyme-linked immunosorbent assay for detecting antibodies to Borna disease virus.
Journal of clinical microbiology 1997;35(7):1661-6.
1997: S Fujiwara; Hideyuki Takahashi; T Nakaya; Y Nakamura; K Nakamura; K Iwahashi; H Kazamatsuri; Shuji Iritani; Noriomi Kuroki; Kenji Ikeda; Kazuyoshi Ikuta
Microplate hybridization for Borna disease virus RNA in human peripheral blood mononuclear cells.
Clinical and diagnostic laboratory immunology 1997;4(3):387-91.
1997: Yasuji Arase; Kenji Ikeda; N Murashima; K Chayama; Akihito Tsubota; I Koida; Y Suzuki; S Saitoh; M Kobayashi; Hiromitsu Kumada
The long term efficacy of glycyrrhizin in chronic hepatitis C patients.
Cancer 1997;79(8):1494-500.
1997: Kenji Ikeda; S Saitoh; Y Suzuki; I Koida; Akihito Tsubota; M Kobayashi; Yasuji Arase; K Chayama; N Murashima; Hiromitsu Kumada
A prospective randomized administration of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization.
American journal of clinical oncology 1997;20(2):202-8.
1997: T Nakamura; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
[Cranial MRI in the patients with chronic liver disease (CLD)].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1997;94(3):157-62.
1997: Kazuaki Chayama; Akihito Tsubota; Masahiro Kobayashi; K Okamoto; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection.
Hepatology (Baltimore, Md.) 1997;25(3):745-9.
1997: Takuji Okusaka; Shuichi Okada; H Ishii; H Nose; H Nagahama; H Nakasuka; Kenji Ikeda; M Yoshimori
Prognosis of hepatocellular carcinoma patients with extrahepatic metastases.
Hepato-gastroenterology 1997;44(13):251-7.
1996: Kenji Ikeda; Kazuaki Chayama; Satoshi Saitoh; I Koida; Y Suzuki; A Tsubota; M Kobayashi; Yasuji Arase; N Murashima; H Kumada
Hepatitis C virus subtype 3b infection in a hospital in Japan: epidemiological study.
Journal of gastroenterology 1996;31(6):801-5.
1996: A Tsubota; H Kumada; Kazuaki Chayama; Yasuji Arase; Satoshi Saitoh; I Koida; N Murashima; Y Suzuki; M Kobayashi; K Takagi; M Kobayashi; Kenji Ikeda
Relationship between pretreatment viremia level and response to interferon-alpha therapy in chronic hepatitis C differs in viral type 1 and 2 infections.
Digestive diseases and sciences 1996;41(10):1925-32.
1996: Yasuji Arase; Kazuaki Chayama; A Tsubota; N Murashima; Y Suzuki; I Koida; M Kobayashi; S Saitoh; Kenji Ikeda; H Kumada; M Kobayashi; H Suzuki
A randomized, double-blind, controlled trial of natural interferon-beta therapy for e-antigen-negative chronic hepatitis B patients with abnormal transaminase levels.
Journal of gastroenterology 1996;31(4):559-64.
1996: M Yano; H Kumada; Masayoshi Kage; Kenji Ikeda; Kazuhide Shimamatsu; O Inoue; E Hashimoto; J H Lefkowitch; J Ludwig; K Okuda
The long-term pathological evolution of chronic hepatitis C.
Hepatology (Baltimore, Md.) 1996;23(6):1334-40.
1996: Kazuaki Chayama; A Tsubota; M Kobayashi; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Kumada
A pilot study of corticosteroid priming for lymphoblastoid interferon alfa in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 1996;23(5):953-7.
1995: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; M Hashimoto; M Kobayashi; M Kanda; T Morinaga
Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C.
Journal of hepatology 1995;23(6):648-53.
1995: Takashi Hosaka; K Yamamoto; Kenji Ikeda; F Taniyama; J Yanagisawa
Application of the relaxation technique in general hospital psychiatry.
Psychiatry and clinical neurosciences 1995;49(5-6):259-62.
1995: Kenji Ikeda
[Hepatocellular carcinogenesis in type B liver cirrhosis].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 2):667-72.
1995: Satoshi Saitoh; Kenji Ikeda; I Koida; Y Suzuki; M Kobayashi; A Tsubota; Yasuji Arase; Kazuaki Chayama; N Murashima; H Kumada
Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein.
Cancer 1995;76(7):1139-44.
1995: H Komachi; K Tsuchiya; M Ikeda; R Koike; T Matsunaga; Kenji Ikeda
Radiation myelopathy: a clinicopathological study with special reference to correlation between MRI findings and neuropathology.
Journal of the neurological sciences 1995;132(2):228-32.
1995: Kenji Ikeda
[Radical and multimodality therapy for hepatitis C virus-related hepatocellular carcinoma].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 1):821-7.
1995: Kenji Ikeda
[Clinical features of hepatitis C virus-related liver cancer].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 1):764-9.
1995: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Serial hemodynamic measurements in well-differentiated hepatocellular carcinomas.
Hepatology (Baltimore, Md.) 1995;21(6):1530-4.
1995: Kenji Ikeda; S Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
A prospective randomized evaluation of a compound of tegafur and uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization.
American journal of clinical oncology 1995;18(3):204-10.
1995: Kazuaki Chayama; M Kobayashi; A Tsubota; I Koida; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; H Kumada
Molecular analysis of intraspousal transmission of hepatitis C virus.
Journal of hepatology 1995;22(4):431-9.
1994: Kazuaki Chayama; A Tsubota; I Koida; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; H Kumada
Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C.
The Journal of general virology 1994;75 ( Pt 12)():3623-8.
1994: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas.
Cancer 1994;74(11):2918-23.
1994: M Kobayashi; H Kumada; Kazuaki Chayama; Yasuji Arase; S Saitou; A Tsubota; I Koida; Kenji Ikeda; M Hashimoto; S Iwasaki
Prevalence of HCV genotype among patients with chronic liver diseases in the Tokyo metropolitan area.
Journal of gastroenterology 1994;29(5):583-7.
1994: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Small hepatocellular carcinoma: evaluation of portal blood flow with CT during arterial portography performed with balloon occlusion of the hepatic artery.
Radiology 1994;193(1):67-70.
1994: S Saito; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; M Kanda; M Kobayashi; H Kumada
[The diagnosis of hepatocellular carcinoma determined by pattern of AFP bands separated by Con A affinity electrophoresis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1994;91(8):1301-8.
1994: Kenji Ikeda; Satoshi Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Imaging diagnosis of small hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1994;20(1 Pt 1):82-7.
1994: Yasuji Arase; H Kumada; Kazuaki Chayama; A Tsubota; I Koida; Kenji Ikeda; Satoshi Saitoh; T Matsumoto; M Kobayashi
Interferon retreatment of nonresponders with HCV-RNA-positive chronic hepatitis C.
Journal of gastroenterology 1994;29(3):299-304.
1994: A Tsubota; Kazuaki Chayama; Kenji Ikeda; A Yasuji; I Koida; Satoshi Saitoh; M Hashimoto; S Iwasaki; M Kobayashi; K Hiromitsu
Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection.
Hepatology (Baltimore, Md.) 1994;19(5):1088-94.
1994: Kazuaki Chayama; Yasuji Arase; I Koida; A Tsubota; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; M Kanda; S Iwasaki; M Kobayashi
Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C.
Journal of gastroenterology and hepatology 1994;9(2):128-33.
1994: Kenji Ikeda; H Kumada
[Long-term prognosis of liver cirrhosis].
Nihon rinsho. Japanese journal of clinical medicine 1994;52(1):63-8.
1993: K Ikeda; Haruhiko Akiyama; H Kondo; Kenji Ikeda
Anti-tau-positive glial fibrillary tangles in the brain of postencephalitic parkinsonism of Economo type.
Neuroscience letters 1993;162(1-2):176-8.
1993: A Tsubota; Kazuaki Chayama; Yasuji Arase; I Koida; Satoshi Saitoh; Kenji Ikeda; S Iwasaki; T Matsumoto; M Kobayashi; H Kumada
Factors useful in predicting the response to interferon therapy in chronic hepatitis C.
Journal of gastroenterology and hepatology 1993;8(6):535-9.
1993: Kenji Ikeda; Satoshi Saitoh; I Koida; Yasuji Arase; A Tsubota; Kazuaki Chayama; H Kumada; M Kawanishi
A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis.
Hepatology (Baltimore, Md.) 1993;18(1):47-53.
1993: Kenji Ikeda; Satoshi Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography.
Hepatology (Baltimore, Md.) 1993;17(6):1003-7.
1993: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; Y Sakai; M Kobayashi; T Morinaga; H Kumada
Effect of lymphoblastoid alfa-interferon in patients with chronic hepatitis C having different genotypic subtype of hepatitis C virus.
Gastroenterologia Japonica 1993;28 Suppl 5():45-7.
1993: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; I Koida; Kenji Ikeda; T Matsumoto; M Kobayashi; S Iwasaki; S Koyama
Genotypic subtyping of hepatitis C virus.
Journal of gastroenterology and hepatology 1993;8(2):150-6.
1993: Kenji Ikeda; Satoshi Saitoh; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada; G Watanabe; M Tsurumaru
Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma.
Cancer 1993;71(1):19-25.
1992: Yasuji Arase; H Kumada; Kazuaki Chayama; A Tsubota; Kenji Ikeda; Satoshi Saitoh; Y Sakai; T Matsumoto; M Kobayashi
Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis.
Gastroenterologia Japonica 1992;27(5):646-51.
1992: Y Namba; H Tsuchiya; Kenji Ikeda
Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease.
Neuroscience letters 1992;134(2):264-6.
1991: Kenji Ikeda; H Kumada; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama
Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the Cox proportional hazard model.
Cancer 1991;68(10):2150-4.
1991: Kazuaki Chayama; Yasuji Arase; S Saito; Kenji Ikeda; H Kumada; T Matsumoto; M Kobayashi; Y Sakai; T Morinaga
[Clinical features and viral markers in patients with chronic hepatitis positive for both HBs antigen and anti-C-100 antibody].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1991;88(9):2113-8.
1991: Kazuaki Chayama; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; T Matsumoto; Y Sakai; M Kobayashi; M Unakami; T Morinaga; H Kumada
Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 1991;13(6):1040-3.
1989: Kenji Ikeda; H Kumada; Yasuji Arase; Kazuaki Chayama; Satoshi Saitoh; H Komeichi; A Yoshiba; M Irimoto
[Remission state and five-year survival after transcatheter arterial embolization therapy in patients with hepatocellular carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1989;86(9):2215-22.
1989: Satoshi Saitoh; H Kumada; Kenji Ikeda; Kazuaki Chayama; Yasuji Arase; A Yoshiba; M Unakami
[Seven cases of acute exacerbation accompanied with icterus and ascites in chronic type B hepatitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1989;86(2):261-4.
1988: H Kumada; Kenji Ikeda; Y Arase; S Saito; H Komeji
[Study on the family clustering of non-A, non-B chronic hepatitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1988;85(12):2695.
1988: Kenji Ikeda; H Kumada; Yasuji Arase; Kazuaki Chayama; T Gunji; A Yoshiba; M Irimoto
[Risk factors for side effects of long-term administration of 5-fluorouracil derivatives in patients with hepatocellular carcinoma associated with liver cirrhosis--relationship with serum concentration of anti-tumor agents and side effect].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1988;85(11):2411-9.
1988: Yasuji Arase; H Kumada; Kenji Ikeda; I Nakamura; K Chayama; S Saito; T Gunji; N Murasima; K Takeuchi; M Nakajima
[The retrospective analysis of the histological course by use of GPT integration value in anti HBe positive cases with abnormal GPT].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1988;85(4):871-5.
1987: Kenji Ikeda; H Kumada; Yasuji Arase; I Nakamura; Kazuaki Chayama; N Murashima; K Takeuchi; M Nakajima; A Yoshiba; M Irimoto
[Effects and side effects of long-term administration of oral antitumor agents in patients with hepatocellular carcinoma--especially, relation to aggravation of liver function].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1987;84(10):2377-85.
1986: Kenji Ikeda; H Kumada; I Nakamura; Yasuji Arase; Y Nozawa; A Yoshiba; M Irimoto
[Repeated transcatheter arterial embolization therapy of hepatocellular carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1986;83(12):2563-70.
1985: Kenji Ikeda; H Kumada; T Mori; N Murashima; A Yoshiba; M Unakami
[A case of recurrent hepatitis with eosinophilia and eosinophilic infiltration in the liver].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1985;82(7):1791-4.
1984: Kenji Ikeda; E Oyake; H Kumada; K Takeuchi; M Nakajima; A Yoshiba; M Irimoto
[Evaluation of transcatheter arterial embolization therapy for hepatocellular carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1984;81(2):249-53.
1982: A Hori; G Fischer; B Dietrich-Schott; Kenji Ikeda
Dimyelia, diplomyelia, and diastematomyelia.
Clinical neuropathology 1982;1(1):23-30.
1978: Kenji Ikeda; S Ikeda; T Yoshimura; H Kato; M Namba
Neuropathology of secondary generalized epilepsy--(Lennox-Gastaut syndrome)--a case report.
Folia psychiatrica et neurologica japonica 1978;32(1):129-39.