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Belinda Avalos

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A Mahindra; B Pohlman; L Rybicki; R Sobecks; J Sweetenham; S Tench; S Andresen; Belinda R Avalos; B J Bolwell; R Dean; S Devine; P Elder; M Kalaycio; E Copelan
Etoposide plus G-CSF priming compared with G-CSF alone in patients with lymphoma improves mobilization without an increased risk of secondary myelodysplasia and leukemia.
Belinda R Avalos; Aleksandr Lazaryan; Edward A Copelan
Can G-CSF cause leukemia in hematopoietic stem cell donors?
Shubham Pant; Mehdi Hamadani; Anthony J Dodds; Jeff Szer; Pamela Crilley; Dustin Stevenson; Gary Phillips; Patrick J Elder; Ian Nivison-Smith; Belinda R Avalos; Sam Penza; David Topolsky; Ronald Sobecks; Matt Kalaycio; Brian J Bolwell; Edward A Copelan
Incidence and reasons for late failure after allogeneic haematopoietic cell transplantation following BuCy2 in acute myeloid leukaemia.

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All Publications

2012: A Mahindra; B Pohlman; L Rybicki; R Sobecks; J Sweetenham; S Tench; S Andresen; Belinda R Avalos; B J Bolwell; R Dean; S Devine; P Elder; M Kalaycio; E Copelan
Etoposide plus G-CSF priming compared with G-CSF alone in patients with lymphoma improves mobilization without an increased risk of secondary myelodysplasia and leukemia.
Bone marrow transplantation 2012;47(2):231-5.
2011: Belinda R Avalos; Aleksandr Lazaryan; Edward A Copelan
Can G-CSF cause leukemia in hematopoietic stem cell donors?
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(12):1739-46.
2010: Shubham Pant; Mehdi Hamadani; Anthony J Dodds; Jeff Szer; Pamela Crilley; Dustin Stevenson; Gary Phillips; Patrick J Elder; Ian Nivison-Smith; Belinda R Avalos; Sam Penza; David Topolsky; Ronald Sobecks; Matt Kalaycio; Brian J Bolwell; Edward A Copelan
Incidence and reasons for late failure after allogeneic haematopoietic cell transplantation following BuCy2 in acute myeloid leukaemia.
British journal of haematology 2010;148(4):623-6.
2010: Melissa G Piper; Pam R Massullo; Megan Loveland; Lawrence J Druhan; Tamila L Kindwall-Keller; Jing Ai; Alexander Copelan; Belinda R Avalos
Neutrophil elastase downmodulates native G-CSFR expression and granulocyte-macrophage colony formation.
Journal of inflammation (London, England) 2010;7(1):5.
2008: Tamila L Kindwall-Keller; Lawrence J Druhan; Jing Ai; Melissa G Hunter; Pam Massullo; Megan Loveland; Belinda R Avalos
Role of the proteasome in modulating native G-CSFR expression.
Cytokine 2008;43(2):114-23.
2008: Jing Ai; Lawrence J Druhan; Melissa G Hunter; Megan J Loveland; Belinda R Avalos
LRG-accelerated differentiation defines unique G-CSFR signaling pathways downstream of PU.1 and C/EBPepsilon that modulate neutrophil activation.
Journal of leukocyte biology 2008;83(5):1277-85.
2008: Jing Ai; Lawrence J Druhan; Megan J Loveland; Belinda R Avalos
G-CSFR ubiquitination critically regulates myeloid cell survival and proliferation.
PloS one 2008;3(10):e3422.
2008: Melissa G Hunter; Morgan McLemore; Daniel C Link; Megan Loveland; Alexander Copelan; Belinda R Avalos
Divergent pathways in COS-7 cells mediate defective internalization and intracellular routing of truncated G-CSFR forms in SCN/AML.
PloS one 2008;3(6):e2452.
2007: Don M Benson; Patrick J Elder; Thomas S Lin; William Blum; Sam Penza; Belinda R Avalos; Edward A Copelan; Sherif S Farag
High-dose melphalan versus busulfan, cyclophosphamide, and etoposide as preparative regimens for autologous stem cell transplantation in patients with multiple myeloma.
Leukemia research 2007;31(8):1069-75.
2006: Navin Wadehra; Sherif S Farag; Brian J Bolwell; Patrick J Elder; Sam Penza; Matt Kalaycio; Belinda R Avalos; Brad Pohlman; Guido Marcucci; Ronald Sobecks; Thomas Lin; Steven Andrèsen; Edward A Copelan
Long-term outcome of Hodgkin disease patients following high-dose busulfan, etoposide, cyclophosphamide, and autologous stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(12):1343-9.
2006: William Blum; Brian J Bolwell; Gary Phillips; Sherif S Farag; Thomas S Lin; Belinda R Avalos; Sam Penza; Guido Marcucci; John C Byrd; Matt Kalaycio; Ronald Sobecks; Brad Pohlman; Stacey Brown; Patrick J Elder; Edward A Copelan
High disease burden is associated with poor outcomes for patients with acute myeloid leukemia not in remission who undergo unrelated donor cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(1):61-7.
2005: Robert Littleton; Sam Penza; Belinda R Avalos; Edward A Copelan
Syngeneic vs. allotransplantation in chronic myeloid leukemia: all's well that ends well.
Transplantation 2005;80(3):426-7.
2005: Pam Massullo; Lawrence J Druhan; Bruce A Bunnell; Melissa G Hunter; John M Robinson; Clay B Marsh; Belinda R Avalos
Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes.
Blood 2005;105(9):3397-404.
2005: Thomas S Lin; Sam Penza; Belinda R Avalos; M R Lucarelli; Sherif S Farag; John C Byrd; Edward A Copelan
Diffuse alveolar hemorrhage following gemtuzumab ozogamicin.
Bone marrow transplantation 2005;35(8):823-4.
2005: Sherif S Farag; Brian J Bolwell; Patrick J Elder; Matt Kalaycio; Thomas Lin; Brad Pohlman; Sam Penza; Guido Marcucci; William Blum; Ronald Sobecks; Belinda R Avalos; John C Byrd; Edward A Copelan
High-dose busulfan, cyclophosphamide, and etoposide does not improve outcome of allogeneic stem cell transplantation compared to BuCy2 in patients with acute myeloid leukemia.
Bone marrow transplantation 2005;35(7):653-61.
2005: Lawrence J Druhan; Jing Ai; Pam Massullo; Tamila Kindwall-Keller; Mark A Ranalli; Belinda R Avalos
Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia.
Blood 2005;105(2):584-91.
2004: Melissa G Hunter; Anand Jacob; Lynn C O'Donnell; Amanda Agler; Lawrence J Druhan; K Mark Coggeshall; Belinda R Avalos
Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5036-45.
2004: Edward A Copelan; Stacy Hoshaw-Woodard; Patrick J Elder; Sam Penza; Sherif S Farag; Guido Marcucci; Thomas Lin; SA Ezzone; MD Scholl; Thomas Bechtel; Stanley Lemeshow; Belinda R Avalos
Therapy-related myelodysplasia and leukemia occur infrequently following VP-16 priming and autotransplantation without total body irradiation.
Bone marrow transplantation 2004;34(1):85-7.
2003: Melissa G Hunter; Lawrence J Druhan; Pam Massullo; Belinda R Avalos
Proteolytic cleavage of granulocyte colony-stimulating factor and its receptor by neutrophil elastase induces growth inhibition and decreased cell surface expression of the granulocyte colony-stimulating factor receptor.
American journal of hematology 2003;74(3):149-55.
2003: Sherif S Farag; Patrick J Elder; Guido Marcucci; Sam Penza; Ewa Mrozek; A Molina; Thomas Lin; Belinda R Avalos; Edward A Copelan
Radiation-free regimens result in similar outcomes of allogeneic hematopoietic progenitor cell transplantation in patients aged >or=50 years compared to younger adults with low-risk disease.
Bone marrow transplantation 2003;31(2):87-93.
2002: Lynn C O'Donnell; Lawrence J Druhan; Belinda R Avalos
Molecular characterization and expression analysis of leucine-rich alpha2-glycoprotein, a novel marker of granulocytic differentiation.
Journal of leukocyte biology 2002;72(3):478-85.
2002: Thomas S Lin; Belinda R Avalos; Sam Penza; Guido Marcucci; Patrick J Elder; Edward A Copelan
Second autologous stem cell transplant for multiply relapsed Hodgkin's disease.
Bone marrow transplantation 2002;29(9):763-7.
2001: Edward A Copelan; Thomas Bechtel; Belinda R Avalos; Patrick J Elder; SA Ezzone; MD Scholl; Sam Penza
Busulfan levels are influenced by prior treatment and are associated with hepatic veno-occlusive disease and early mortality but not with delayed complications following marrow transplantation.
Bone marrow transplantation 2001;27(11):1121-4.
2000: Edward A Copelan; Sam Penza; Karl S Theil; Patrick J Elder; Thomas Bechtel; MB Tighe; SA Ezzone; MD Scholl; P S Belt; Donn C Young; Belinda R Avalos
The influence of early transplantation, age, GVHD prevention regimen, and other factors on outcome of allogeneic transplantation for CML following BuCy.
Bone marrow transplantation 2000;26(10):1037-43.
2000: Richard A Nash; Joseph H Antin; Chatchada Karanes; Joseph W Fay; Belinda R Avalos; A M Yeager; Donna Przepiorka; S Davies; F B Petersen; P Bartels; Donald N Buell; William E Fitzsimmons; Claudio Anasetti; Rainer Storb; Voravit Ratanatharathorn
Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors.
Blood 2000;96(6):2062-8.
2000: Edward A Copelan; Sam Penza; Brad Pohlman; Belinda R Avalos; Marlene Goormastic; Steven Andresen; Matt Kalaycio; Thomas Bechtel; MD Scholl; Patrick J Elder; SA Ezzone; Lynn C O'Donnell; MB Tighe; G L Risley; Donn C Young; Brian J Bolwell
Autotransplantation following busulfan, etoposide and cyclophosphamide in patients with non-Hodgkin's lymphoma.
Bone marrow transplantation 2000;25(12):1243-8.
2000: Edward A Copelan; Sam Penza; Patrick J Elder; SA Ezzone; MD Scholl; Thomas Bechtel; P S Belt; Belinda R Avalos
Analysis of prognostic factors for allogeneic marrow transplantation following busulfan and cyclophosphamide in myelodysplastic syndrome and after leukemic transformation.
Bone marrow transplantation 2000;25(12):1219-22.
2000: Melissa G Hunter; Belinda R Avalos
Granulocyte colony-stimulating factor receptor mutations in severe congenital neutropenia transforming to acute myelogenous leukemia confer resistance to apoptosis and enhance cell survival.
Blood 2000;95(6):2132-7.
1999: Melissa G Hunter; Belinda R Avalos
Deletion of a critical internalization domain in the G-CSFR in acute myelogenous leukemia preceded by severe congenital neutropenia.
Blood 1999;93(2):440-6.
1998: Voravit Ratanatharathorn; Richard A Nash; Donna Przepiorka; Steven M Devine; Jared L Klein; Daniel Weisdorf; Joseph W Fay; Auayporn Nademanee; Joseph H Antin; Neal Christiansen; R van der Jagt; Roger H Herzig; Mark R Litzow; Steven Neil Wolff; W L Longo; F B Petersen; Chatchada Karanes; Belinda R Avalos; Rainer Storb; Donald N Buell; Rochelle M Maher; William E Fitzsimmons; John R Wingard
Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation.
Blood 1998;92(7):2303-14.
1998: Melissa G Hunter; Belinda R Avalos
Phosphatidylinositol 3'-kinase and SH2-containing inositol phosphatase (SHIP) are recruited by distinct positive and negative growth-regulatory domains in the granulocyte colony-stimulating factor receptor.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(10):4979-87.
1998: Belinda R Avalos
The granulocyte colony-stimulating factor receptor and its role in disorders of granulopoiesis.
Leukemia & lymphoma 1998;28(3-4):265-73.
1997: Edward A Copelan; S K Ceselski; SA Ezzone; Larry C Lasky; Sam Penza; Thomas Bechtel; J L Klein; D M Hehmeyer; MD Scholl; D D Marshall; Patrick J Elder; G L Risley; Belinda R Avalos
Mobilization of peripheral-blood progenitor cells with high-dose etoposide and granulocyte colony-stimulating factor in patients with breast cancer, non-Hodgkin's lymphoma, and Hodgkin's disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(2):759-65.
1997: Belinda R Avalos; JM Parker; D A Ware; Melissa G Hunter; K A Sibert; Brian J Druker
Dissociation of the Jak kinase pathway from G-CSF receptor signaling in neutrophils.
Experimental hematology 1997;25(2):160-8.
1996: E M Bluman; G S Schnier; Belinda R Avalos; Matthew P Strout; H Sultan; F W Jacobson; D E Williams; William E Carson; Michael A Caligiuri
The c-kit ligand potentiates the allogeneic mixed lymphocyte reaction.
Blood 1996;88(10):3887-93.
1996: E A Copelan; S L Penza; Patrick J Elder; P S Belt; M D Scholl; D M Hehmeyer; S A Ezzone; T P Bechtel; Belinda R Avalos
Influence of graft-versus-host disease on outcome following allogeneic transplantation with radiation-free preparative therapy in patients with advanced leukemia.
Bone marrow transplantation 1996;18(5):907-11.
1996: Belinda R Avalos
Molecular analysis of the granulocyte colony-stimulating factor receptor.
Blood 1996;88(3):761-77.
1996: Michael J Styler; Pamela Crilley; J Biggs; J Moul; E Copelan; D Topolsky; Belinda R Avalos; S Penza; P Sabol; K Downs; J Szer; Irina Brodsky; D I Marks
Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis.
Bone marrow transplantation 1996;18(1):171-6.
1996: E M Bluman; K J Bartynski; Belinda R Avalos; Michael A Caligiuri
Human natural killer cells produce abundant macrophage inflammatory protein-1 alpha in response to monocyte-derived cytokines.
The Journal of clinical investigation 1996;97(12):2722-7.
1996: F Sahebi; E Copelan; Pamela Crilley; Brian J Bolwell; Belinda R Avalos; J Klein; Mary Territo; James L Gajewski
Unrelated allogeneic bone marrow transplantation using high-dose busulfan and cyclophosphamide (BU-CY) for the preparative regimen.
Bone marrow transplantation 1996;17(5):685-9.
1996: J L Klein; Belinda R Avalos; P Belt; C A Taylor; S A Ezzone; M D Scholl; J Fisher; D Young; E A Copelan
Bone marrow engraftment following unrelated donor transplantation utilizing busulfan and cyclophosphamide preparatory chemotherapy.
Bone marrow transplantation 1996;17(4):479-83.
1995: Belinda R Avalos; Melissa G Hunter; JM Parker; S K Ceselski; Brian J Druker; Seth J Corey; Veela B Mehta
Point mutations in the conserved box 1 region inactivate the human granulocyte colony-stimulating factor receptor for growth signal transduction and tyrosine phosphorylation of p75c-rel.
Blood 1995;85(11):3117-26.
1995: M Kalaycioglu; E Copelan; Belinda R Avalos; J Klein; Marlene Goormastic; Brian J Bolwell
Survival after ABO-incompatible allogeneic bone marrow transplant after a preparative regimen of busulfan and cyclophosphamide.
Bone marrow transplantation 1995;15(1):105-10.
1994: Belinda R Avalos; K J Bartynski; Patrick J Elder; M S Kotur; W G Burton; N M Wilkie
The active monomeric form of macrophage inflammatory protein-1 alpha interacts with high- and low-affinity classes of receptors on human hematopoietic cells.
Blood 1994;84(6):1790-801.
1994: Belinda R Avalos; V C Broudy; S K Ceselski; Brian J Druker; James D Griffin; W P Hammond
Abnormal response to granulocyte colony-stimulating factor (G-CSF) in canine cyclic hematopoiesis is not caused by altered G-CSF receptor expression.
Blood 1994;84(3):789-94.
1994: C A Keever; N Leong; I Cunningham; E A Copelan; Belinda R Avalos; J Klein; N Kapoor; Patrick W Adams; Charles G Orosz; P J Tutschka
HLA-B44-directed cytotoxic T cells associated with acute graft-versus-host disease following unrelated bone marrow transplantation.
Bone marrow transplantation 1994;14(1):137-45.
1994: E A Copelan; T P Bechtel; J P Klein; J L Klein; P Tutschka; N Kapoor; N C Featheringham; Belinda R Avalos
Controlled trial of orally administered immunoglobulin following bone marrow transplantation.
Bone marrow transplantation 1994;13(1):87-91.
1993: Belinda R Avalos; E A Copelan
Second autologous bone marrow transplantation in Hodgkin's disease.
Bone marrow transplantation 1993;12(6):665-7.
1993: Belinda R Avalos; J L Klein; N Kapoor; E A Copelan
Allogeneic bone marrow transplantation following busulfan and 90 mg/kg of cyclophosphamide.
Bone marrow transplantation 1993;12(6):655-8.
1993: C A Keever; J Klein; N Leong; E A Copelan; Belinda R Avalos; N Kapoor; I Cunningham; P J Tutschka
Effect of GVHD on the recovery of NK cell activity and LAK precursors following BMT.
Bone marrow transplantation 1993;12(3):289-95.
1993: Belinda R Avalos; J L Klein; N Kapoor; P J Tutschka; J P Klein; E A Copelan
Preparation for marrow transplantation in Hodgkin's and non-Hodgkin's lymphoma using Bu/CY.
Bone marrow transplantation 1993;12(2):133-8.
1993: E A Copelan; Jim Biggs; J Szer; J M Thompson; Pamela Crilley; I Brodsky; J L Klein; N Kapoor; G S Harman; Belinda R Avalos
Allogeneic bone marrow transplantation for acute myelogenous leukemia, acute lymphocytic leukemia, and multiple myeloma following preparation with busulfan and cyclophosphamide (BuCy2).
Seminars in oncology 1993;20(4 Suppl 4):33-8; quiz 39.
1993: Irina Brodsky; Jim Biggs; J Szer; Pamela Crilley; K Atkinson; K Downs; Anthony J Dodds; A J Concannon; Belinda R Avalos; P Tutschka
Treatment of chronic myelogenous leukemia with allogeneic bone marrow transplantation after preparation with busulfan and cyclophosphamide (BuCy2): an update.
Seminars in oncology 1993;20(4 Suppl 4):27-31; quiz 32.
1992: Jim Biggs; J Szer; Pamela Crilley; K Atkinson; K Downs; Anthony J Dodds; A J Concannon; Belinda R Avalos; P Tutschka; N Kapoor
Treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation after preparation with BuCy2.
Blood 1992;80(5):1352-7.
1992: E A Copelan; Belinda R Avalos; N Kapoor; T Bechtel; P J Tutschka
Alternate applications of immunoglobulin following bone marrow transplantation.
Seminars in hematology 1992;29(3 Suppl 2):96-9.
1992: N Kapoor; A E Pelligrini; E A Copelan; I Cunningham; Belinda R Avalos; J L Klein; P J Tutschka
Psoralen plus ultraviolet A (PUVA) in the treatment of chronic graft versus host disease: preliminary experience in standard treatment resistant patients.
Seminars in hematology 1992;29(2):108-12.
1992: E A Copelan; Jim Biggs; Belinda R Avalos; J Szer; I Cunningham; J P Klein; K Atkinson; N Kapoor; J L Klein; K Downs
Radiation-free preparation for allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(2):237-42.
1991: A M Ghany; P J Tutschka; R B McGhee; Belinda R Avalos; I Cunningham; N Kapoor; E A Copelan
Cyclosporine-associated seizures in bone marrow transplant recipients given busulfan and cyclophosphamide preparative therapy.
Transplantation 1991;52(2):310-5.
1991: E A Copelan; Jim Biggs; J M Thompson; Pamela Crilley; J Szer; J P Klein; N Kapoor; Belinda R Avalos; I Cunningham; K Atkinson
Treatment for acute myelocytic leukemia with allogeneic bone marrow transplantation following preparation with BuCy2.
Blood 1991;78(3):838-43.
1991: P J Tutschka; E A Copelan; N Kapoor; Belinda R Avalos; J P Klein
Allogeneic bone marrow transplantation for leukemia using chemotherapy as conditioning: 6-year results of a single institution trial.
Transplantation proceedings 1991;23(1 Pt 2):1709-10.
1990: Belinda R Avalos; Judith C Gasson; Cyrus V Hedvat; S G Quan; Gayle Cocita Baldwin; R H Weisbart; R E Williams; David W Golde; J F DiPersio
Human granulocyte colony-stimulating factor: biologic activities and receptor characterization on hematopoietic cells and small cell lung cancer cell lines.
Blood 1990;75(4):851-7.
1989: Gayle Cocita Baldwin; Judith C Gasson; S E Kaufman; S G Quan; R E Williams; Belinda R Avalos; A F Gazdar; David W Golde; J F DiPersio
Nonhematopoietic tumor cells express functional GM-CSF receptors.
Blood 1989;73(4):1033-7.
1988: Belinda R Avalos; S E Kaufman; Masao Tomonaga; R E Williams; David W Golde; Judith C Gasson
K562 cells produce and respond to human erythroid-potentiating activity.
Blood 1988;71(6):1720-5.