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Susumu Ikehara

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TOP 3
Ming Shi; Yasushi Adachi; Yunze Cui; Ming Li; Lin Liu; Susumu Ikehara
CD4+ T cell-depleted lymphocyte infusion impairs neither the recovery of recipient thymus nor the development of transplanted thymus.
Ming Li; Susumu Ikehara
Bone marrow stem cell as a potential treatment for diabetes.
Ming Li; Susumu Ikehara
Bone-marrow-derived mesenchymal stem cells for organ repair.

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All Publications

2013: Ming Shi; Yasushi Adachi; Yunze Cui; Ming Li; Lin Liu; Susumu Ikehara
CD4+ T cell-depleted lymphocyte infusion impairs neither the recovery of recipient thymus nor the development of transplanted thymus.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2976-83.
2013: Ming Li; Susumu Ikehara
Bone marrow stem cell as a potential treatment for diabetes.
Journal of diabetes research 2013;2013():329596.
2013: Ming Li; Susumu Ikehara
Bone-marrow-derived mesenchymal stem cells for organ repair.
Stem cells international 2013;2013():132642.
2013: Tomohiko Shimo; Junji Takaya; Shoji Tsuji; Kazuo Umezawa; Sohsaku Yamanouchi; Yasushi Adachi; Susumu Ikehara; Takahisa Kimata; Mitsuhiko Okigaki; Kazunari Kaneko
A Novel Nuclear Factor κB Inhibitor, Dehydroxymethylepoxyquinomicin, Ameliorates Puromycin Aminonucleoside-Induced Nephrosis in Mice.
American journal of nephrology 2013;37():302-9.
2012: Ming Li; Joseph I Shapiro; Ming Shi; Takashi Takaki; Luca Vanella; Yuming Zhang; Susumu Ikehara
Stem cell transplantation increases antioxidant effects in diabetic mice.
International journal of biological sciences 2012;8(10):1335-44.
2012: Chieko Shima; Kanji Takahashi; Seiji Yanai; Yasushi Adachi; Yuichiro Imai; Keizo Minamino; Mitsuhiko Okigaki; Ming Shi; Susumu Ikehara
Neuroprotective effects of granulocyte colony-stimulating factor on ischemia-reperfusion injury of the retina.
Ophthalmic research 2012;48(4):199-207.
2011: Susumu Ikehara
A novel BMT technique for treatment of various currently intractable diseases.
Best practice & research. Clinical haematology 2011;24(3):477-83.
2011: Naoki Hosaka; Takashi Takaki; Kosyo Takasu; Kunio Uesaka; Yuming Zhang; Susumu Ikehara
Poorly differentiated squamous cell carcinoma of the nipple: a unique case for marked exophytic growth, but little invasion with neuroendocrine differentiation.
Medical molecular morphology 2011;44(3):174-8.
2011: Shinichiro Mori; Shosaku Nomura; Yoshihisa Yamamoto; Shinya Fujita; Shirou Fukuhara; Ming Li; Susumu Ikehara
Perfusion method for bone marrow cell collection in poor mobilizer lymphoma patient.
International journal of hematology 2011;93(6):822-4.
2011: Ming Shi; Yasushi Adachi; Yunze Cui; Ming Li; Zhexiong Lian; Yuming Zhang; Seiji Yanai; Chieko Shima; Yuichiro Imai; Susumu Ikehara
Combination of intra-bone marrow-bone marrow transplantation and subcutaneous donor splenocyte injection diminishes risk of graft-versus-host disease and enhances survival rate.
Stem cells and development 2011;20(5):759-68.
2011: Kenichi Oe; Taketoshi Kushida; Naofumi Okamoto; Masayuki Umeda; Tomohisa Nakamura; Susumu Ikehara; Hirokazu Iida
New strategies for anterior cruciate ligament partial rupture using bone marrow transplantation in rats.
Stem cells and development 2011;20(4):671-9.
2011: Yuming Zhang; Naoki Hosaka; Yunze Cui; Ming Shi; Susumu Ikehara
Effects of allogeneic hematopoietic stem cell transplantation plus thymus transplantation on malignant tumors: comparison between fetal, newborn, and adult mice.
Stem cells and development 2011;20(4):599-607.
2011: Susumu Ikehara
Thymus transplantation for treatment of cancer: lessons from murine models.
Expert review of clinical immunology 2011;7(2):205-11.
2011: Koko Katagiri; Yoshihiro Ueda; Takashi Tomiyama; Kaneki Yasuda; Yoshinobu Toda; Susumu Ikehara; Keiichi I Nakayama; Tatsuo Kinashi
Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip1.
Immunity 2011;34(1):24-38.
2010: Naofumi Okamoto; Taketoshi Kushida; Kenichi Oe; Masayuki Umeda; Susumu Ikehara; Hirokazu Iida
Treating Achilles tendon rupture in rats with bone-marrow-cell transplantation therapy.
The Journal of bone and joint surgery. American volume 2010;92(17):2776-84.
2010: Ming Li; Nader G Abraham; Luca Vanella; Yuming Zhang; Muneo Inaba; Naoki Hosaka; Sho-Ichi Hoshino; Ming Shi; Yoko Miyamoto Ambrosini; M Eric Gershwin; Susumu Ikehara
Successful modulation of type 2 diabetes in db/db mice with intra-bone marrow--bone marrow transplantation plus concurrent thymic transplantation.
Journal of autoimmunity 2010;35(4):414-23.
2010: Akio Shigematsu; Ming Shi; Mitsuhiko Okigaki; Yasushi Adachi; Naoko Koike; Jishan Che; Masayoshi Iwasaki; Hiroaki Matsubara; Masahiro Imamura; Susumu Ikehara
Signaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantation.
Stem cells and development 2010;19(11):1679-86.
2010: Yunze Cui; Shuji Nakamura; Ming Shi; Wei Feng; Wenhao Cui; Kequan Guo; Yuming Zhang; Susumu Ikehara
A successful haploidentical bone marrow transplantation method in rabbits: perfusion method plus intra-bone marrow-bone marrow transplantation.
Transplant immunology 2010;24(1):33-9.
2010: Naoki Hosaka; Wenhao Cui; Yuming Zhang; Takashi Takaki; Muneo Inaba; Susumu Ikehara
Prolonged survival in mice with advanced tumors treated with syngeneic or allogeneic intra-bone marrow-bone marrow transplantation plus fetal thymus transplantation.
Cancer immunology, immunotherapy : CII 2010;59(7):1121-30.
2010: Xiaoli Wang; Hiroko Hisha; Tomomi Mizokami; Wenhao Cui; Yunze Cui; Aiping Shi; Changye Song; Satoshi Okazaki; Qing Li; Wei Feng; Junko Kato; Susumu Ikehara
Mouse mesenchymal stem cells can support human hematopoiesis both in vitro and in vivo: the crucial role of neural cell adhesion molecule.
Haematologica 2010;95(6):884-91.
2010: Shoichi Hoshino; Muneo Inaba; Hiroshi Iwai; Tomoki Ito; Ming Li; M Eric Gershwin; Kazuichi Okazaki; Susumu Ikehara
The role of dendritic cell subsets in 2,4,6-trinitrobenzene sulfonic acid-induced ileitis.
Journal of autoimmunity 2010;34(4):380-9.
2010: C Shima; Yashusi Adachi; M Shi; Y Imai; Mitsuhiko Okigaki; S Yanai; Keizo Minamino; K Takahashi; Susumu Ikehara
The combination method using magnetic beads and a magnet helps sustain the number of donor BM cells after intra-BM injection, resulting in rapid hematopoietic recovery.
Bone marrow transplantation 2010;45(6):993-9.
2010: Yuichiro Imai; Yasushi Adachi; Ming Shi; Chieko Shima; Seiji Yanai; Mitsuhiko Okigaki; Tetsumori Yamashima; Kazunari Kaneko; Susumu Ikehara
Caspase inhibitor ZVAD-fmk facilitates engraftment of donor hematopoietic stem cells in intra-bone marrow-bone marrow transplantation.
Stem cells and development 2010;19(4):461-8.
2010: Susumu Ikehara
The future of stem cell transplantation in autoimmune disease.
Clinical reviews in allergy & immunology 2010;38(2-3):292-7.
2010: Seiji Yanai; Yasushi Adachi; Ming Shi; Akio Shigematsu; Chieko Shima; Yuichiro Imai; A-Hon Kwon; Susumu Ikehara
Adult bone marrow cells can differentiate into hemopoietic cells and endothelial cells but not into other lineage cells in normal growth and normal life.
International journal of hematology 2010;91(2):213-8.
2010: Wei Feng; Yunze Cui; Hongsheng Zhan; Ming Shi; Wenhao Cui; Kequan Guo; Qing Li; Changye Song; Yuming Zhang; Takahide Mori; M Eric Gershwin; Nader G Abraham; Susumu Ikehara
Prevention of premature ovarian failure and osteoporosis induced by irradiation using allogeneic ovarian/bone marrow transplantation.
Transplantation 2010;89(4):395-401.
2009: Ming Li; Muneo Inaba; Kequan Guo; Nader G Abraham; Susumu Ikehara
Amelioration of cognitive ability in senescence-accelerated mouse prone 8 (SAMP8) by intra-bone marrow-bone marrow transplantation.
Neuroscience letters 2009;465(1):36-40.
2009: Shizuo Ohnishi; Hidefumi Ito; Yasuhiro Suzuki; Yasushi Adachi; Reika Wate; Jianhua Zhang; Satoshi Nakano; Hirofumi Kusaka; Susumu Ikehara
Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis.
Brain research 2009;1296():216-24.
2009: Susumu Ikehara
A new bone marrow transplantation method for stem cell disorders.
Annals of the New York Academy of Sciences 2009;1173():774-80.
2009: Yoko Tokuyama; Yasushi Adachi; Keizo Minamino; Hiroshi Shintaku; Mitsuhiko Okigaki; Kumi Hayashi; Aiko Kitajima; Takashi Takaki; Naoko Koike; Chieko Shima; Yuichiro Imai; Ming Shi; Seiji Yanai; Susumu Ikehara
Abnormal distribution of dendritic cells in (NZW x BXSB)F1 mice.
Autoimmunity 2009;42(5):399-405.
2009: Seiji Yanai; Yasushi Adachi; Jun-Ichi Fuijisawa; Shiwen Jiang; Mitsuhiko Okigaki; Ming Shi; Chieko Shima; Yuichiro Imai; A-Hon Kwon; Susumu Ikehara
Anti-tumor effects of fusion cells of type 1 dendritic cells and Meth A tumor cells using hemagglutinating virus of Japan-envelope.
International journal of oncology 2009;35(2):249-55.
2009: T Nishida; Naoki Hosaka; T Takaki; T Miyake; Wenhao Cui; Muneo Inaba; Hidefumi Kinoshita; Tadashi Matsuda; Susumu Ikehara
Allogeneic intra-BM-BMT plus adult thymus transplantation from same donor has benefits for long-term survival even after sublethal irradiation or low-dose BM cell injection.
Bone marrow transplantation 2009;43(11):829-37.
2009: Taketoshi Kushida; Yusuke Ueda; Masayuki Umeda; Kenichi Oe; Naofumi Okamoto; Hirokazu Iida; Nader G Abraham; M Eric Gershwin; Susumu Ikehara
Allogeneic intra-bone marrow transplantation prevents rheumatoid arthritis in SKG/Jcl mice.
Journal of autoimmunity 2009;32(3-4):216-22.
2009: Tomomi Mizokami; Hiroko Hisha; Satoshi Okazaki; Takashi Takaki; Xiao-Li Wang; Chang-Ye Song; Qing Li; Junko Kato; Naoki Hosaka; Muneo Inaba; Hideharu Kanzaki; Susumu Ikehara
Preferential expansion of human umbilical cord blood-derived CD34-positive cells on major histocompatibility complex-matched amnion-derived mesenchymal stem cells.
Haematologica 2009;94(5):618-28.
2009: Takashi Miyake; Naoki Hosaka; Wenhao Cui; Teruhisa Nishida; Takashi Takaki; Muneo Inaba; Yasuo Kamiyama; Susumu Ikehara
Adult thymus transplantation with allogeneic intra-bone marrow-bone marrow transplantation from same donor induces high thymopoiesis, mild graft-versus-host reaction and strong graft-versus-tumour effects.
Immunology 2009;126(4):552-64.
2009: Masayuki Umeda; Taketoshi Kushida; Kunihiko Sasai; Taku Asada; Kenichi Oe; Daisuke Sakai; Joji Mochida; Susumu Ikehara; Hirokazu Iida
Activation of rat nucleus pulposus cells by coculture with whole bone marrow cells collected by the perfusion method.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2009;27(2):222-8.
2008: Takashi Takaki; Naoki Hosaka; Takashi Miyake; Wenhao Cui; Teruhisa Nishida; Muneo Inaba; Susumu Ikehara
Presence of donor-derived thymic epithelial cells in [B6-->MRL/lpr] mice after allogeneic intra-bone marrow-bone marrow transplantation (IBM-BMT).
Journal of autoimmunity 2008;31(4):408-15.
2008: Susumu Ikehara
Stem cell transplantation for autoimmune diseases: what can we learn from experimental models?
Autoimmunity 2008;41(8):563-9.
2008: Naoko Koike-Kiriyama; Yashusi Adachi; Masayoshi Iwasaki; Y Amou; Akio Shigematsu; Yasushi Koike; Keizo Minamino; Hiromi Mukaide; M Shi; S Yanai; Miyo Matsumura; Susumu Ikehara
High mortality rate of (NZW x BXSB)F1 mice induced by administration of lipopolysaccharide attributes to high production of tumour necrosis factor-alpha by increased numbers of dendritic cells.
Clinical and experimental immunology 2008;154(2):285-93.
2008: Junko Kato; Hiroko Hisha; Xiao-Li Wang; Tomomi Mizokami; Satoshi Okazaki; Qing Li; Chang-Ye Song; Masahiko Maki; Naoki Hosaka; Yasushi Adachi; Muneo Inaba; Susumu Ikehara
Contribution of neural cell adhesion molecule (NCAM) to hemopoietic system in monkeys.
Annals of hematology 2008;87(10):797-807.
2008: Ming Shi; Yasushi Adachi; Akio Shigematsu; Naoko Koike-Kiriyama; Wei Feng; Seji Yanai; Cui Yunze; Zhe-Xiong Lian; Juan Li; Susumu Ikehara
Intra-bone marrow injection of donor bone marrow cells suspended in collagen gel retains injected cells in bone marrow, resulting in rapid hemopoietic recovery in mice.
Stem cells (Dayton, Ohio) 2008;26(9):2211-6.
2008: Kimiko Tatsumi; Hajime Otani; Daisuke Sato; Chiharu Enoki; Toshiji Iwasaka; Hiroji Imamura; Shoichiro Taniuchi; Kazunari Kaneko; Yasushi Adachi; Susumu Ikehara
Granulocyte-colony stimulating factor increases donor mesenchymal stem cells in bone marrow and their mobilization into peripheral circulation but does not repair dystrophic heart after bone marrow transplantation.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(8):1351-8.
2008: Satoshi Okazaki; Hiroko Hisha; Tomomi Mizokami; Takashi Takaki; Xiaoli Wang; Changye Song; Qing Li; Junko Kato; Yasuo Kamiyama; Susumu Ikehara
Successful acceptance of adult liver allografts by intra-bone marrow-bone marrow transplantation.
Stem cells and development 2008;17(4):629-39.
2008: Stephen J Peterson; George Drummond; Dong Hyun Kim; Ming Li; Adam L Kruger; Susumu Ikehara; Nader G Abraham
L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice.
Journal of lipid research 2008;49(8):1658-69.
2008: Ming Li; Dong Hyun Kim; Peter L Tsenovoy; Stephen J Peterson; Rita Rezzani; Luigi Rodella; Wilbert S Aronow; Susumu Ikehara; Nader G Abraham
Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance.
Diabetes 2008;57(6):1526-35.
2008: Yugo Ando; Muneo Inaba; Yutaku Sakaguchi; Masanobu Tsuda; Guo Ke Quan; Mariko Omae; Kazuichi Okazaki; Susumu Ikehara
Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats.
Inflammatory bowel diseases 2008;14(6):826-38.
2008: Hiroshi Iwai; Susumu Baba; Mariko Omae; Shinryu Lee; Toshio Yamashita; Susumu Ikehara
Maintenance of systemic immune functions prevents accelerated presbycusis.
Brain research 2008;1208():8-16.
2008: Hiromi Mukaide; Yasushi Adachi; Shigeru Taketani; Masayoshi Iwasaki; Naoko Koike-Kiriyama; Akio Shigematsu; Ming Shi; Seiji Yanai; Kazuhiko Yoshioka; Yasuo Kamiyama; Susumu Ikehara
FKBP51 expressed by both normal epithelial cells and adenocarcinoma of colon suppresses proliferation of colorectal adenocarcinoma.
Cancer investigation 2008;26(4):385-90.
2008: T Asada; Taketoshi Kushida; M Umeda; K Oe; H Matsuya; T Wada; K Sasai; Susumu Ikehara; Hirokazu Iida
Prevention of corticosteroid-induced osteonecrosis in rabbits by intra-bone marrow injection of autologous bone marrow cells.
Rheumatology (Oxford, England) 2008;47(5):591-6.
2008: Susumu Ikehara
A novel method of bone marrow transplantation (BMT) for intractable autoimmune diseases.
Journal of autoimmunity 2008;30(3):108-15.
2008: Nader G Abraham; Ming Li; Luca Vanella; Stephen J Peterson; Susumu Ikehara; David Asprinio
Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: role of heme oxygenase-adiponectin.
Journal of autoimmunity 2008;30(3):128-35.
2008: Wenhao Cui; Naoki Hosaka; Takashi Miyake; Xiaoli Wang; Kequan Guo; Yunze Cui; Qiang Li; Changye Song; Wei Feng; Qing Li; Takashi Takaki; Teruhisa Nishida; Muneo Inaba; Susumu Ikehara
Analysis of tolerance induction using triple chimeric mice: major histocompatibility complex-disparate thymus, hemopoietic cells, and microenvironment.
Transplantation 2008;85(8):1151-8.
2008: Mariko Omae; Muneo Inaba; Yutaku Sakaguchi; Masanobu Tsuda; Takashi Miyake; Jyunichi Fukui; Hiroshi Iwai; Toshio Yamashita; Susumu Ikehara
Long-term maintenance of donor-derived hematopoiesis by intra-bone marrow-bone marrow transplantation.
Stem cells and development 2008;17(2):291-302.
2008: T Miyake; Muneo Inaba; Junichi Fukui; Yusuke Ueda; Naoki Hosaka; Yasuo Kamiyama; Susumu Ikehara
Prevention of graft-versus-host disease by intrabone marrow injection of donor T cells: involvement of bone marrow stromal cells.
Clinical and experimental immunology 2008;152(1):153-62.
2008: Yutaku Sakaguchi; Muneo Inaba; Masanobu Tsuda; G K Quan; Mariko Omae; Y Ando; Kazushige Uchida; Kazuichi Okazaki; Susumu Ikehara
The Wistar Bonn Kobori rat, a unique animal model for autoimmune pancreatitis with extrapancreatic exocrinopathy.
Clinical and experimental immunology 2008;152(1):1-12.
2008: Takashi Ryu; N Hosaka; T Miyake; W Cui; T Nishida; T Takaki; Ming Li; Keiji Kawamoto; Susumu Ikehara
Transplantation of newborn thymus plus hematopoietic stem cells can rescue supralethally irradiated mice.
Bone marrow transplantation 2008;41(7):659-66.
2008: Kequan Guo; Muneo Inaba; Ming Li; Jun An; Wenhao Cui; Changye Song; Jianfeng Wang; Yunze Cui; Yutaku Sakaguchi; Masanobu Tsuda; Mariko Omae; Yugo Ando; Qing Li; Xiaoli Wang; Wei Feng; Susumu Ikehara
Long-term donor-specific tolerance in rat cardiac allografts by intrabone marrow injection of donor bone marrow cells.
Transplantation 2008;85(1):93-101.
2008: Changye Song; Hiroko Hisha; Xiaoli Wang; Qing Li; Ming Li; Wenhao Cui; Kequan Guo; Satoshi Okazaki; Tomomi Mizokami; Junko Kato; Yunze Cui; Wei Feng; Yuming Zhang; Ming Shi; Muneo Inaba; Hongxue Fan; Susumu Ikehara
Facilitation of hematopoietic recovery by bone grafts with intra-bone marrow-bone marrow transplantation.
Immunobiology 2008;213(6):455-68.
2008: Akio Shigematsu; Yasushi Adachi; Junko Matsubara; Hiromi Mukaide; Naoko Koike-Kiriyama; Keizo Minamino; Ming Shi; Seiji Yanai; Masahiro Imamura; Shigeru Taketani; Susumu Ikehara
Analyses of expression of cytoglobin by immunohistochemical studies in human tissues.
Hemoglobin 2008;32(3):287-96.
2008: Yasuhiro Suzuki; Yasushi Adachi; Yuming Zhang; Keizo Minamino; Masayoshi Iwasaki; Hiromi Mukaide; Ming Shi; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Naoko Koike-Kiriyama; Akio Shigematsu; Seiji Yanai; Susumu Ikehara
Administration of granulocyte colony-stimulating factor to recipients followed by intra-bone marrow-bone marrow transplantation accelerates acceptance of allogeneic bone marrow cells in mice.
Immunobiology 2008;213(5):427-35.
2007: Wei Feng; Yunze Cui; Changye Song; Hongsheng Zhan; Xiaoli Wang; Qing Li; Wenhao Cui; Kequan Guo; Masahiko Maki; Hiroko Hisha; Takahide Mori; Susumu Ikehara
Prevention of osteoporosis and hypogonadism by allogeneic ovarian transplantation in conjunction with intra-bone marrow-bone marrow transplantation.
Transplantation 2007;84(11):1459-66.
2007: M Li; Muneo Inaba; K Q Guo; Hiroko Hisha; N G Abraham; Susumu Ikehara
Treatment of streptozotocin-induced diabetes mellitus in mice by intra-bone marrow bone marrow transplantation plus portal vein injection of beta cells induced from bone marrow cells.
International journal of hematology 2007;86(5):438-45.
2007: Masanobu Tsuda; Muneo Inaba; Yutaku Sakaguchi; Junichi Fukui; Yusuke Ueda; Mariko Omae; Y Ando; Hiromi Mukaide; Kequan Guo; T Yabuki; T Nakatani; Susumu Ikehara
Activation of granulocytes by direct interaction with dendritic cells.
Clinical and experimental immunology 2007;150(2):322-31.
2007: Guo-Xiang Yang; Zhe-Xiong Lian; Ya-Hui Chuang; Shang-an Shu; Yuki Moritoki; Ruth Y Lan; K Wakabayashi; Aftab A Ansari; Kenneth Dorshkind; Susumu Ikehara; M Eric Gershwin
Generation of functionally distinct B lymphocytes from common myeloid progenitors.
Clinical and experimental immunology 2007;150(2):349-57.
2007: Naoko Koike-Kiriyama; Yasushi Koike; Yashusi Adachi; Hiromi Mukaide; Keizo Minamino; Akio Shigematsu; Y Kamiama; Miyo Matsumura; Susumu Ikehara
Intra-bone marrow injection of dendritic cells for treatment of malignant tumor in mice.
Journal of experimental & clinical cancer research : CR 2007;26(3):337-42.
2007: Muneo Inaba; Yasushi Adachi; Hiroko Hisha; Naoki Hosaka; Masahiko Maki; Yusuke Ueda; Yasushi Koike; Takeshi Miyake; Junichi Fukui; Yunze Cui; Hiromi Mukaide; Naoko Koike; Mariko Omae; Tomomi Mizokami; Akio Shigematsu; Yutaku Sakaguchi; Masanobu Tsuda; Satoshi Okazaki; Xiaoli Wang; Qing Li; Akihisa Nishida; Yugo Ando; Kequan Guo; Changye Song; Wenhao Cui; Wei Feng; Junko Katou; Katuyuki Sado; Shuji Nakamura; Susumu Ikehara
Extensive studies on perfusion method plus intra-bone marrow-bone marrow transplantation using cynomolgus monkeys.
Stem cells (Dayton, Ohio) 2007;25(8):2098-103.
2007: Stephen J Peterson; Daniel Husney; Adam L Kruger; Rafal Olszanecki; Francesca Ricci; Luigi Rodella; Alessandra Stacchiotti; Rita Rezzani; John A McClung; Wilbert S Aronow; Susumu Ikehara; Nader G Abraham
Long-term treatment with the apolipoprotein A1 mimetic peptide increases antioxidants and vascular repair in type I diabetic rats.
The Journal of pharmacology and experimental therapeutics 2007;322(2):514-20.
2007: Ming Li; Stephen Peterson; Daniel Husney; Muneo Inaba; Kequan Guo; Eri Terada; Toshisuke Morita; Kiran Patil; Attallah Kappas; Susumu Ikehara; Nader G Abraham
Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin.
Antioxidants & redox signaling 2007;9(7):855-63.
2007: Tomoyuki Yoshihara; Masayoshi Ohta; Yutaka Itokazu; Naoya Matsumoto; Mari Dezawa; Yoshihisa Suzuki; Akihiko Taguchi; Yumi Watanabe; Yasushi Adachi; Susumu Ikehara; Hisashi Sugimoto; Chizuka Ide
Neuroprotective effect of bone marrow-derived mononuclear cells promoting functional recovery from spinal cord injury.
Journal of neurotrauma 2007;24(6):1026-36.
2007: Hiromi Mukaide; Yasushi Adachi; Naoko Koike-Kiriyama; Yasuhiro Suzuki; Keizo Minamino; Masayoshi Iwasaki; Masanobu Tsuda; Keiji Nakano; Yasushi Koike; Akio Shigematsu; Yasuo Kamiyama; Susumu Ikehara
Immunotherapy for malignant tumors using combination of allogeneic intra-bone marrow-bone marrow transplantation, donor lymphocyte infusion and dendritic cells.
International journal of oncology 2007;30(6):1309-15.
2007: Junichi Fukui; Muneo Inaba; Yusuke Ueda; Takashi Miyake; Naoki Hosaka; A-Hon Kwon; Yutaku Sakaguchi; Masanobu Tsuda; Mariko Omae; Yasuo Kamiyama; Susumu Ikehara
Prevention of graft-versus-host disease by intra-bone marrow injection of donor T cells.
Stem cells (Dayton, Ohio) 2007;25(6):1595-601.
2007: Yusuke Ueda; Muneo Inaba; Keizo Takada; Junichi Fukui; Yutaku Sakaguchi; Masanobu Tsuda; Mariko Omae; Taketoshi Kushida; Hirokazu Iida; Susumu Ikehara
Induction of senile osteoporosis in normal mice by intra-bone marrow-bone marrow transplantation from osteoporosis-prone mice.
Stem cells (Dayton, Ohio) 2007;25(6):1356-63.
2007: Qing Li; Hiroko Hisha; Ryoji Yasumizu; Tian-Xue Fan; Guo-Xiang Yang; Qiang Li; Yun-Ze Cui; Xiao-Li Wang; Chang-Ye Song; Satoshi Okazaki; Tomomi Mizokami; Wenhao Cui; Kequan Guo; Ming Li; Wei Feng; Junko Katou; Susumu Ikehara
Analyses of very early hemopoietic regeneration after bone marrow transplantation: comparison of intravenous and intrabone marrow routes.
Stem cells (Dayton, Ohio) 2007;25(5):1186-94.
2007: Xiaoli Wang; Hiroko Hisha; Wenhao Cui; Changye Song; Tomomi Mizokami; Satoshi Okazaki; Qing Li; Wei Feng; Junko Kato; Shiwen Jiang; Hongxue Fan; Susumu Ikehara
The characteristics of hematopoietic stem cells from autoimmune-prone mice and the role of neural cell adhesion molecules in abnormal proliferation of these cells in MRL/lpr mice.
Haematologica 2007;92(3):300-7.
2007: Naoki Hosaka; Takashi Ryu; T Miyake; Wenhao Cui; T Nishida; T Takaki; Muneo Inaba; Susumu Ikehara
Treatment of autoimmune diseases in MRL/lpr mice by allogenic bone marrow transplantation plus adult thymus transplantation.
Clinical and experimental immunology 2007;147(3):555-63.
2007: Ming Li; Stephen Peterson; Daniel Husney; Muneo Inaba; Kequan Guo; Attallah Kappas; Susumu Ikehara; Nader G Abraham
Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice.
Cell cycle (Georgetown, Tex.) 2007;6(5):567-71.
2007: Saadet Turkseven; George Drummond; Rita Rezzani; Luigi Rodella; Shuo Quan; Susumu Ikehara; Nader G Abraham
Impact of silencing HO-2 on EC-SOD and the mitochondrial signaling pathway.
Journal of cellular biochemistry 2007;100(4):815-23.
2007: Yasushi Koike; Yasushi Adachi; Yasuhiro Suzuki; Masayoshi Iwasaki; Naoko Koike-Kiriyama; Keizo Minamino; Keiji Nakano; Hiromi Mukaide; Akio Shigematsu; Yasuhiko Kiyozuka; Airo Tubura; Yasuo Kamiyama; Susumu Ikehara
Allogeneic intrabone marrow-bone marrow transplantation plus donor lymphocyte infusion suppresses growth of colon cancer cells implanted in skin and liver of rats.
Stem cells (Dayton, Ohio) 2007;25(2):385-91.
2007: Tomoyuki Okada; Muneo Inaba; Mitsuru Naiki; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Comparative immunobiology of thymic DC mRNA in autoimmune-prone mice.
Journal of autoimmunity 2007;28(1):41-5.
2007: Naoko Koike-Kiriyama; Yasushi Adachi; Keizo Minamino; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Haruhiko Yamada; Hiromi Mukaide; Akio Shigematsu; Tomomi Mizokami; Miyo Matsumura; Susumu Ikehara
Human cord blood cells can differentiate into retinal nerve cells.
Acta neurobiologiae experimentalis 2007;67(4):359-65.
2007: Susumu Ikehara
Innovative BMT methods for intractable diseases.
Immunologic research 2007;38(1-3):251-60.
2007: Chunfu Li; Yuelin He; Xiaoqin Feng; Muneo Inaba; Yasushi Adachi; Keizo Takada; Yuming Zhang; Yoshihisa Yamamoto; Xuedong Wu; Yunze Cui; Masayoshi Iwasaki; Hiroko Hisha; Naoki Hosaka; Mitsuru Taira; Keizo Minamino; Yasuhiro Suzuki; Keiji Nakano; Junichi Fukui; Yusuke Ueda; Yasushi Koike; Masanobu Tsuda; Susumu Ikehara
An innovative approach to bone marrow collection and transplantation in a patient with beta-thalassemia major: marrow collection using a perfusion method followed by intra-bone marrow injection of collected bone marrow cells.
International journal of hematology 2007;85(1):73-7.
2007: Akio Shigematsu; Yasushi Adachi; Naoko Koike-Kiriyama; Yasuhiro Suzuki; Masayoshi Iwasaki; Yasushi Koike; Keiji Nakano; Hiromi Mukaide; Masahiro Imamura; Susumu Ikehara
Effects of low-dose irradiation on enhancement of immunity by dendritic cells.
Journal of radiation research 2007;48(1):51-5.
2006: Qiang Li; Naoki Hosaka; Wenhao Cui; Xiaoli Wang; Yunze Cui; Yunze Cui; Changye Song; Qing Li; Takashi Ryu; Tianxue Fan; Keiji Kawamoto; Susumu Ikehara
Lin(-)CD34(-) bone marrow cells from adult mice can differentiate into neural-like cells.
Neuroscience letters 2006;408(1):51-6.
2006: Yutaku Sakaguchi; Muneo Inaba; Kimihide Kusafuka; Kazuichi Okazaki; Susumu Ikehara
Establishment of animal models for three types of pancreatitis and analyses of regeneration mechanisms.
Pancreas 2006;33(4):371-81.
2006: Kazuya Ikebukuro; Yashusi Adachi; Yasuhiro Suzuki; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Hiromi Mukaide; Y Yamada; S Fujimoto; Y Seino; Haruki Oyaizu; Akio Shigematsu; Naoko Kiriyama; Y Hamada; Yasuo Kamiyama; Susumu Ikehara
Synergistic effects of injection of bone marrow cells into both portal vein and bone marrow on tolerance induction in transplantation of allogeneic pancreatic islets.
Bone marrow transplantation 2006;38(10):657-64.
2006: Yasushi Adachi; Haruki Oyaizu; Shigeru Taketani; Keizo Minamino; Kazuyuki Yamaguchi; Leonard D Shultz; Masayoshi Iwasaki; Minoru Tomita; Yasuhiro Suzuki; Keiji Nakano; Yasushi Koike; Ryoji Yasumizu; Makoto Sata; Noriyuki Hirama; Isao Kubota; Shirou Fukuhara; Susumu Ikehara
Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa.
Stem cells (Dayton, Ohio) 2006;24(9):2071-7.
2006: Yuming Zhang; Yasushi Adachi; Yasuhiro Suzuki; Keizo Minamino; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Hiromi Mukaide; Akio Shigematsu; Naoko Kiriyama; Chunfu Li; Susumu Ikehara
Synergistic effects of granulocyte-colony stimulating factor and macrophage-colony stimulating factor on recovery of donor hematopoietic cells in allogeneic bone marrow transplantation.
Oncology reports 2006;16(2):367-71.
2006: Naoki Hosaka; Takashi Ryu; W Cui; Q Li; A Nishida; T Miyake; T Takaki; M Inaba; Susumu Ikehara
Relationship of p53, Bcl-2, Ki-67 index and E-cadherin expression in early invasive breast cancers with comedonecrosis as an accelerated apoptosis.
Journal of clinical pathology 2006;59(7):692-8.
2006: Yuming Zhang; Yasushi Adachi; Masayoshi Iwasaki; Keizo Minamino; Yasuhiro Suzuki; Keiji Nakano; Yasushi Koike; Hiromi Mukaide; Akio Shigematsu; Naoko Kiriyama; Chunfu Li; Susumu Ikehara
G-CSF and/or M-CSF accelerate differentiation of bone marrow cells into endothelial progenitor cells in vitro.
Oncology reports 2006;15(6):1523-7.
2006: Keiji Nakano; Yasushi Adachi; Keizo Minamino; Masayoshi Iwasaki; Akio Shigematsu; Naoko Kiriyama; Yasuhiro Suzuki; Yasushi Koike; Hiromi Mukaide; Shoichiro Taniuchi; Yohnosuke Kobayashi; Kazunari Kaneko; Susumu Ikehara
Mechanisms underlying acceleration of blood flow recovery in ischemic limbs by macrophage colony-stimulating factor.
Stem cells (Dayton, Ohio) 2006;24(5):1274-9.
2006: Xiaoli Wang; Hiroko Hisha; Shigeru Taketani; Yasushi Adachi; Qing Li; Wenhao Cui; Yunze Cui; Jianfeng Wang; Changye Song; Tomomi Mizokami; Satoshi Okazaki; Qiang Li; Tianxue Fan; Hongxue Fan; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Characterization of mesenchymal stem cells isolated from mouse fetal bone marrow.
Stem cells (Dayton, Ohio) 2006;24(3):482-93.
2006: Keizo Takada; Muneo Inaba; Naoya Ichioka; Yusuke Ueda; Mitsuru Taira; Susumu Baba; Tomomi Mizokami; Xiaoli Wang; Hiroko Hisha; Hirokazu Iida; Susumu Ikehara
Treatment of senile osteoporosis in SAMP6 mice by intra-bone marrow injection of allogeneic bone marrow cells.
Stem cells (Dayton, Ohio) 2006;24(2):399-405.
2005: Guo-Xiang Yang; Zhe-Xiong Lian; Kentaro Kikuchi; Yuki Moritoki; Aftab A Ansari; Yong-Jun Liu; Susumu Ikehara; M Eric Gershwin
Plasmacytoid dendritic cells of different origins have distinct characteristics and function: studies of lymphoid progenitors versus myeloid progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7281-7.
2005: Hiroshi Iwai; Shinryu Lee; Muneo Inaba; Susumu Baba; Toshio Yamashita; Susumu Ikehara
Bone marrow transplantation as a strategy for the treatment of autoimmune hearing loss in MRL/Mp-lpr/lpr mice.
Journal of neuroimmunology 2005;168(1-2):76-82.
2005: Masayoshi Iwasaki; Yasushi Adachi; Takashi Nishiue; Keizo Minamino; Yasuhiro Suzuki; Yuming Zhang; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Hiromi Mukaide; Shigeru Taketani; Fumio Yuasa; Hirohito Tsubouchi; EIICHI GOHDA; Toshiji Iwasaka; Susumu Ikehara
Hepatocyte growth factor delivered by ultrasound-mediated destruction of microbubbles induces proliferation of cardiomyocytes and amelioration of left ventricular contractile function in Doxorubicin-induced cardiomyopathy.
Stem cells (Dayton, Ohio) 2005;23(10):1589-97.
2005: Xiaoli Wang; Hiroko Hisha; Shigeru Taketani; Muneo Inaba; Qiang Li; Wenhao Cui; Changye Song; Tianxue Fan; Yunze Cui; Kequan Guo; Guoxiang Yang; Hongxue Fan; Zhe-Xiong Lian; M Eric Gershwin; Susumu Ikehara
Neural cell adhesion molecule contributes to hemopoiesis-supporting capacity of stromal cell lines.
Stem cells (Dayton, Ohio) 2005;23(9):1389-99.
2005: Hiroyuki Kaneda; Yasushi Adachi; Yukihito Saito; Kazuya Ikebukuro; Hirohisa Machida; Yasuhiro Suzuki; Keizo Minamino; Yuming Zhang; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Hiroji Imamura; Susumu Ikehara
Long-term observation after simultaneous lung and intra-bone marrow-bone marrow transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005;24(9):1415-23.
2005: Keizo Minamino; Yasushi Adachi; Haruhiko Yamada; Akiko Higuchi; Yasuhiro Suzuki; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Hiromi Mukaide; Naoko Kiriyama; Akio Shigematsu; Miyo Matsumura; Susumu Ikehara
Long-term survival of bone marrow-derived retinal nerve cells in the retina.
Neuroreport 2005;16(12):1255-9.
2005: Saadet Turkseven; Adam L Kruger; Christopher J Mingone; Pawel Kaminski; Muneo Inaba; Luigi Rodella; Susumu Ikehara; Michael S Wolin; Nader G Abraham
Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes.
American journal of physiology. Heart and circulatory physiology 2005;289(2):H701-7.
2005: Susumu Ikehara
Intra-bone marrow-bone marrow transplantation: a new strategy for treatment of stem cell disorders.
Annals of the New York Academy of Sciences 2005;1051():626-34.
2005: Kentaro Kikuchi; Zhe-Xiong Lian; Yasuhiko Kimura; Carlo Selmi; Guo-Xiang Yang; Stuart Gordon; Pietro Invernizzi; Mauro Podda; Ross Coppel; Aftab A Ansari; Susumu Ikehara; Hiroshi Miyakawa; M Eric Gershwin
Genetic polymorphisms of toll-like receptor 9 influence the immune response to CpG and contribute to hyper-IgM in primary biliary cirrhosis.
Journal of autoimmunity 2005;24(4):347-52.
2005: Keizo Minamino; Yasushi Adachi; Akiharu Okamura; Taketoshi Kushida; Motohiko Sugi; Masato Watanabe; Koei Muguruma; Hideki Sugao; Yasuhiro Suzuki; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Hiromi Mukaide; Yuming Zhang; Tadashi Matsuda; Miyo Matsumura; Susumu Ikehara
Autopsy case of primary choriocarcinoma of the urinary bladder.
Pathology international 2005;55(4):216-22.
2005: Mitsuru Taira; Muneo Inaba; Keizo Takada; Susumu Baba; Junichi Fukui; Yusuke Ueda; A-Hon Kwon; Hiroko Hisha; Yasuo Kamiyama; Susumu Ikehara
Treatment of streptozotocin-induced diabetes mellitus in rats by transplantation of islet cells from two major histocompatibility complex disparate rats in combination with intra bone marrow injection of allogeneic bone marrow cells.
Transplantation 2005;79(6):680-7.
2005: Guo-Xiang Yang; Zhe-Xiong Lian; Kentaro Kikuchi; Yong-Jun Liu; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
CD4- plasmacytoid dendritic cells (pDCs) migrate in lymph nodes by CpG inoculation and represent a potent functional subset of pDCs.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3197-203.
2005: Yasuhiro Suzuki; Yasushi Adachi; Keizo Minamino; Yuming Zhang; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Susumu Ikehara
A new strategy for treatment of malignant tumor: intra-bone marrow-bone marrow transplantation plus CD4- donor lymphocyte infusion.
Stem cells (Dayton, Ohio) 2005;23(3):365-70.
2005: Keizo Minamino; Yasushi Adachi; Mitsuhiko Okigaki; Hidefumi Ito; Yoshimi Togawa; Kengo Fujita; Minoru Tomita; Yasuhiro Suzuki; Yuming Zhang; Masayoshi Iwasaki; Keiji Nakano; Yasushi Koike; Hiroaki Matsubara; Toshiji Iwasaka; Miyo Matsumura; Susumu Ikehara
Macrophage colony-stimulating factor (M-CSF), as well as granulocyte colony-stimulating factor (G-CSF), accelerates neovascularization.
Stem cells (Dayton, Ohio) 2005;23(3):347-54.
2005: Masayoshi Iwasaki; Yasushi Adachi; Keizo Minamino; Yasuhiro Suzuki; Yuming Zhang; Mitsuhiko Okigaki; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Hiromi Mukaide; Shigeru Taketani; Yasukiyo Mori; Hakuo Takahashi; Toshiji Iwasaka; Susumu Ikehara
Mobilization of bone marrow cells by G-CSF rescues mice from cisplatin-induced renal failure, and M-CSF enhances the effects of G-CSF.
Journal of the American Society of Nephrology : JASN 2005;16(3):658-66.
2005: Kentaro Kikuchi; Zhe-Xiong Lian; Guo-Xiang Yang; Aftab A Ansari; Susumu Ikehara; Marshall Kaplan; Hiroshi Miyakawa; Ross Coppel; M Eric Gershwin
Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis.
Gastroenterology 2005;128(2):304-12.
2005: Susumu Baba; Muneo Inaba; Hiroshi Iwai; Mitsuru Taira; Keizo Takada; Hiroko Hisha; Toshio Yamashita; Susumu Ikehara
Intra-bone marrow-bone marrow transplantation facilitates hemopoietic recovery including dendritic cells.
Immunobiology 2005;210(1):33-42.
2005: Kimihide Kusafuka; Keisuke Nakano; Yuji Hiraki; Chisa Shukunami; Hitoshi Nagatsuka; Noriyuki Nagai; Tamiko Takemura; Yutaku Sakaguchi; Kazuichi Okazaki; Michi Kusafuka; Hiroko Hisha; Susumu Ikehara
Expression and localization of cartilage-specific matrix protein chondromodulin-I mRNA in salivary pleomorphic adenomas.
Virchows Archiv : an international journal of pathology 2005;446(1):34-40.
2004: Zhe-Xiong Lian; Kentaro Kikuchi; Guo-Xiang Yang; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5283-9.
2004: Kyoji Ueda; Yutaka Hanazono; Hiroaki Shibata; Naohide Ageyama; Yasuji Ueda; Satoko Ogata; Toshiaki Tabata; Takeyuki Nagashima; Masaaki Takatoku; Akihiro Kume; Susumu Ikehara; Masafumi Taniwaki; Keiji Terao; Mamoru Hasegawa; Keiya Ozawa
High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(3):469-77.
2004: Kimihide Kusafuka; Toshiyuki Ishiwata; Yuichi Sugisaki; Tamiko Takemura; Michi Kusafuka; Hiroko Hisha; Susumu Ikehara
Lumican expression is associated with the formation of mesenchyme-like elements in salivary pleomorphic adenomas.
The Journal of pathology 2004;203(4):953-60.
2004: Naoki Hosaka; Toshiya Sasaki; Katsutoshi Adachi; Tomoaki Sato; Toshiro Tanaka; Yasuhiro Miura; Takashi Sawai; Junko Toki; Hiroko Hisha; Akiharu Okamura; Kosho Takasu; Susumu Ikehara
Pulmonary sclerosing hemangioma associated with familial adenomatous polyposis.
Human pathology 2004;35(6):764-8.
2004: Shuo Quan; Pawel M Kaminski; Liming Yang; Toshisuke Morita; Muneo Inaba; Susumu Ikehara; Alvin I Goodman; Michael S Wolin; Nader G Abraham
Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats.
Biochemical and biophysical research communications 2004;315(2):509-16.
2004: Yuming Zhang; Yasushi Adachi; Yasuhiro Suzuki; Keizo Minamino; Masayoshi Iwasaki; Hiroko Hisha; Chang-Ye Song; Kimihide Kusafuka; Keiji Nakano; Yasushi Koike; Jianfeng Wang; Eitaku Koh; Yunze Cui; Chunfu Li; Susumu Ikehara
Simultaneous injection of bone marrow cells and stromal cells into bone marrow accelerates hematopoiesis in vivo.
Stem cells (Dayton, Ohio) 2004;22(7):1256-62.
2004: Tian-Xue Fan; Hiroko Hisha; Tie-Nan Jin; Kikuya Sugiura; Muneo Inaba; Guo-Xiang Yang; Qiang Li; Xiao-Li Wang; Chang-Ye Song; Yun-Ze Cui; Qing Li; Yuming Zhang; Xiao-Guang Zhang; Hong-Xue Fan; Susumu Ikehara
Induction of tolerance in quadruple chimeric mice.
Stem cells (Dayton, Ohio) 2004;22(5):683-95.
2004: Koichi Nakamura; Muneo Inaba; Kikuya Sugiura; Tomoo Yoshimura; A-Hon Kwon; Yasuo Kamiyama; Susumu Ikehara
Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intra-bone marrow bone marrow transplantation plus donor lymphocyte infusion.
Stem cells (Dayton, Ohio) 2004;22(2):125-34.
2004: Hiroshi Iwai; Shinryu Lee; Susumu Baba; Koichi Tomoda; Muneo Inaba; Susumu Ikehara; Toshio Yamashita
Bone marrow cells as an origin of immune-mediated hearing loss.
Acta oto-laryngologica 2004;124(1):8-12.
2004: Minoru Tomita; Haruhiko Yamada; Yasushi Adachi; Yunze Cui; Eri Yamada; Akiko Higuchi; Keizo Minamino; Yasuhiko Suzuki; Miyo Matsumura; Susumu Ikehara
Choroidal neovascularization is provided by bone marrow cells.
Stem cells (Dayton, Ohio) 2004;22(1):21-6.
2003: Takashi Esumi; Muneo Inaba; Naoya Ichioka; Taketoshi Kushida; Hirokazu Iida; Susumu Ikehara
Successful allogeneic leg transplantation in rats in conjunction with intra-bone marrow injection of donor bone marrow cells.
Transplantation 2003;76(11):1543-8.
2003: Susumu Ikehara
A new concept of stem cell disorders and their new therapy.
Journal of hematotherapy & stem cell research 2003;12(6):643-53.
2003: Susumu Ikehara
New strategies for allogeneic BMT.
Bone marrow transplantation 2003;32 Suppl 1():S73-5.
2003: T Yoshimura; M Inaba; K Sugiura; T Nakajima; T Ito; K Nakamura; H Kanzaki; Susumu Ikehara
Analyses of dendritic cell subsets in pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) 2003;50(2):137-45.
2003: Kentaro Kikuchi; Zhe-Xiong Lian; Xiaosong He; Aftab A Ansari; Miyuki Ishibashi; Hiroshi Miyakawa; Leonard D Shultz; Susumu Ikehara; M Eric Gershwin
Appearance of human plasma cells following differentiation of human B cells in NOD/SCID mouse spleen.
Clinical & developmental immunology 2003;10(2-4):197-202.
2003: Susumu Ikehara
Treatment of autoimmune diseases in mice by a new method for allogeneic bone marrow transplantation.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2003;7(3):292-7.
2003: Naoki Hosaka; Masaaki Ito; Yoji Taki; Hiroshi Iwai; Junko Toki; Susumu Ikehara
Amyloid A gastrointestinal amyloidosis associated with idiopathic retroperitoneal fibrosis. Report of a rare autopsy case and review of the literature.
Archives of pathology & laboratory medicine 2003;127(6):735-8.
2003: Susumu Ikehara
New strategies for BMT, organ transplantation, and regeneration therapy.
Hematology (Amsterdam, Netherlands) 2003;8(2):77-81.
2003: Tomoyuki Okada; Zhe-Xiong Lian; Mitsuru Naiki; Aftab A Ansari; Susumu Ikehara; M Eric Gershwin
Murine thymic plasmacytoid dendritic cells.
European journal of immunology 2003;33(4):1012-9.
2003: Zhe-Xiong Lian; Tomoyuki Okada; Xiaosong He; hiroto kita; Yong-Jun Liu; Aftab A Ansari; Kentaro Kikuchi; Susumu Ikehara; M Eric Gershwin
Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2323-30.
2003: Hiroshi Iwai; Shinryu Lee; Muneo Inaba; Kikuya Sugiura; Susumu Baba; Koichi Tomoda; Toshio Yamashita; Susumu Ikehara
Correlation between accelerated presbycusis and decreased immune functions.
Experimental gerontology 2003;38(3):319-25.
2003: Junko Toki; Yasushi Adachi; Tienan Jin; Tianxue Fan; Katsunori Takase; Zhe-Xiong Lian; Haruki Hayashi; M Eric Gershwin; Susumu Ikehara
Enhancement of IL-7 following irradiation of fetal thymus.
Immunobiology 2003;207(4):247-58.
2002: Susumu Ikehara
[New strategies for BMT].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(12):2310-7.
2002: Yun-Ze Cui; Hiroko Hisha; Guo-Xiang Yang; Tian-Xue Fan; Tienan Jin; Qing Li; Zhe-Xiong Lian; Susumu Ikehara
Optimal protocol for total body irradiation for allogeneic bone marrow transplantation in mice.
Bone marrow transplantation 2002;30(12):843-9.
2002: Yasushi Adachi; Junko Toki; Kazuya Ikebukuro; Minoru Tomita; Hiroyuki Kaneda; Atsuko Tanabe; Li Jun; Keizo Minamino; Yasuhiro Suzuki; Shigeru Taketani; Susumu Ikehara
Immature dendritic cells (CD11c+ CD3- B220- cells) present in mouse peripheral blood.
Immunobiology 2002;206(4):354-67.
2002: Naoki Hosaka; Shin-ichiro Kitajiri; Harukazu Hiraumi; Hidekazu Nogaki; Junko Toki; Guoxing Yang; Hiroko Hisha; Susumu Ikehara
Ectopic pituitary adenoma with malignant transformation.
The American journal of surgical pathology 2002;26(8):1078-82.
2002: Hideyoshi Toyokawa; Muneo Inaba; Soichiro Takai; Sohei Satoi; Josef Beuth; HL Ko; Yoichi Matsui; A-Hon Kwon; Yasuo Kamiyama; Susumu Ikehara
Enhancement of circulating dendritic cell activity by immunomodulators (OK432 and KP-40).
Anticancer research 2002;22(4):2137-45.
2002: Shin-ichiro Kitajiri; Naoki Hosaka; Harukazu Hiraumi; Tomoko Hirose; Susumu Ikehara
Increased expression of integrin beta-4 in papillary thyroid carcinoma with gross lymph node metastasis.
Pathology international 2002;52(7):438-41.
2002: Naoki Hosaka; Toshinori Minato; Shinsaku Yoshida; Junko Toki; Guoxing Yang; Hiroko Hisha; Susumu Ikehara
Kimura's disease with unusual eosinophilic epithelioid granulomatous reaction: a finding possibly related to eosinophil apoptosis.
Human pathology 2002;33(5):561-4.
2002: Naoki Tada; Masayuki Furukawa; Manabu Ogura; Shoji Arai; Yasushi Adachi; Susumu Ikehara; Toshio Yamashita
Experimental otitis media with effusion induced by leukotriene D4.
Auris, nasus, larynx 2002;29(2):127-32.
2002: Zhe-Xiong Lian; hiroto kita; Tomoyuki Okada; Tom Hsu; Leonard D Shultz; Kenneth Dorshkind; Aftab A Ansari; Susumu Ikehara; Mitsuru Naiki; M Eric Gershwin
Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.
Developmental immunology 2002;9(1):35-45.
2002: Kazuya Ikebukuro; Yasushi Adachi; Yuichiro Yamada; Shimpei Fujimoto; Yutaka Seino; Haruki Oyaizu; Koshiro Hioki; Susumu Ikehara
Treatment of streptozotocin-induced diabetes mellitus by transplantation of islet cells plus bone marrow cells via portal vein in rats.
Transplantation 2002;73(4):512-8.
2002: Susumu Ikehara
Bone marrow transplantation: a new strategy for intractable diseases.
Drugs of today (Barcelona, Spain : 1998) 2002;38(2):103-11.
2002: Susumu Ikehara
[Treatment of intractable diseases by a new bone marrow transplantation method].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2002;25(1):7-13.
2002: Naoya Ichioka; Muneo Inaba; Taketoshi Kushida; Takashi Esumi; Kazuhiko Takahara; Kayo Inaba; Ryokei Ogawa; Hirokazu Iida; Susumu Ikehara
Prevention of senile osteoporosis in SAMP6 mice by intrabone marrow injection of allogeneic bone marrow cells.
Stem cells (Dayton, Ohio) 2002;20(6):542-51.
2002: Hiroko Hisha; Urara Kohdera; Masahiro Hirayama; Haruki Yamada; Tomoko Iguchi-Uehira; Tian-Xue Fan; Yun-Ze Cui; Guo-Xiang Yang; Yongan Li; Kikuya Sugiura; Muneo Inaba; Yohnosuke Kobayashi; Susumu Ikehara
Treatment of Shwachman syndrome by Japanese herbal medicine (Juzen-taiho-to): stimulatory effects of its fatty acids on hemopoiesis in patients.
Stem cells (Dayton, Ohio) 2002;20(4):311-9.
2002: Zhe-Xiong Lian; Tomoyuki Okada; hiroto kita; Tom Hsu; Leonard D Shultz; Kenneth Dorshkind; Aftab A Ansari; Mitsuru Naiki; Susumu Ikehara; M Eric Gershwin
Age-related alterations in the lymphohematopoietic and B-lineage precursor populations in NZB mice.
Stem cells (Dayton, Ohio) 2002;20(4):293-300.
2002: Minoru Tomita; Yasushi Adachi; Haruhiko Yamada; Kanji Takahashi; Katsuji Kiuchi; Haruki Oyaizu; Kazuya Ikebukuro; Hiroyuki Kaneda; Miyo Matsumura; Susumu Ikehara
Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina.
Stem cells (Dayton, Ohio) 2002;20(4):279-83.
2002: Guoxiang Yang; Hiroko Hisha; Yunze Cui; Tianxue Fan; Tienan Jin; Qing Li; Zhe-Xiong Lian; Naoki Hosaka; Yulin Li; Susumu Ikehara
A new assay method for late CFU-S formation and long-term reconstituting activity using a small number of pluripotent hemopoietic stem cells.
Stem cells (Dayton, Ohio) 2002;20(3):241-8.
2002: Taketoshi Kushida; Muneo Inaba; Kazuya Ikebukuro; Naoya Ichioka; Takashi Esumi; Haruki Oyaizu; Tomoo Yoshimura; Takashi Nagahama; Kouichi Nakamura; Tomoki Ito; Hiroko Hisha; Kikuya Sugiura; Ryoji Yasumizu; Hirokazu Iida; Susumu Ikehara
Comparison of bone marrow cells harvested from various bones of cynomolgus monkeys at various ages by perfusion or aspiration methods: a preclinical study for human BMT.
Stem cells (Dayton, Ohio) 2002;20(2):155-62.
2002: Yashusi Adachi; Shigeru Taketani; Junko Toki; Kazuya Ikebukuro; Kikuya Sugiura; Haruki Oyaizu; Ryoji Yasumizu; Minoru Tomita; Hiroyuki Kaneda; Yasuo Amoh; Tomoki Ito; Mitsuhiko Okigaki; Muneo Inaba; Susumu Ikehara
Marked increase in number of dendritic cells in autoimmune-prone (NZW x BXSB)F1 mice with age.
Stem cells (Dayton, Ohio) 2002;20(1):61-72.
2002: Harukazu Hiraumi; Shin-ichiro Kitajiri; Tomoko Hirose; Naoki Hosaka; Junko Toki; Susumu Ikehara
Radiosensitive hemangiopericytoma in the soft palate.
Auris, nasus, larynx 2002;29(1):95-7.
2001: Haruki Oyaizu; Yashusi Adachi; Ryoji Yasumizu; M Ono; Kazuya Ikebukuro; Shirou Fukuhara; Susumu Ikehara
Protection of T cells from radiation-induced apoptosis by Cepharanthin.
International immunopharmacology 2001;1(12):2091-9.
2001: S Lee; Kikuya Sugiura; Takashi Nagahama; H Iwai; Ryoji Yasumizu; Toshio Yamashita; Susumu Ikehara
New method for thyroid transplantation across major histocompatibility complex barriers using allogeneic bone marrow transplantation.
Transplantation 2001;72(6):1144-9.
2001: Hiroshi Iwai; Shinryu Lee; Muneo Inaba; Kikuya Sugiura; Koichi Tomoda; Toshio Yamashita; Susumu Ikehara
Prevention of accelerated presbycusis by bone marrow transplantation in senescence-accelerated mice.
Bone marrow transplantation 2001;28(4):323-8.
2001: Haruki Oyaizu; Yashusi Adachi; T Okumura; Mitsuhiko Okigaki; Naoki Oyaizu; Shigeru Taketani; Kazuya Ikebukuro; Shirou Fukuhara; Susumu Ikehara
Proteasome inhibitor 1 enhances paclitaxel-induced apoptosis in human lung adenocarcinoma cell line.
Oncology reports 2001;8(4):825-9.
2001: Tienan Jin; Junko Toki; Muneo Inaba; Kikuya Sugiura; Tianxue Fan; C Yu; Zhe-Xiong Lian; K Takase; B Feng; Tomoki Ito; Yunze Cui; Guoxiang Yang; Susumu Ikehara
A novel strategy for organ allografts using sublethal (7 Gy) irradiation followed by injection of donor bone marrow cells via portal vein.
Transplantation 2001;71(12):1725-31.
2001: N Taguchi; Y Hashimoto; Tom Hsu; Aftab A Ansari; Leonard D Shultz; Kenneth Dorshkind; Susumu Ikehara; Mitsuru Naiki; M Eric Gershwin
B cells are selectively associated with thymic cortical but not medullary pathology in NZB mice.
Journal of autoimmunity 2001;16(4):393-400.
2001: Susumu Ikehara
Treatment of autoimmune diseases by hematopoietic stem cell transplantation.
Experimental hematology 2001;29(6):661-9.
2001: Taketoshi Kushida; Muneo Inaba; Hiroko Hisha; Naoya Ichioka; Takashi Esumi; Ryokei Ogawa; Hirokazu Iida; Susumu Ikehara
Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice.
Blood 2001;97(10):3292-9.
2001: Kikuya Sugiura; S Lee; T Nagahama; Y Adachi; J Ishikawa; Susumu Ikehara
Tolerance induction across Mls and minor histocompatibility complex by inhibiting activation of T helper type 1 in early period.
Immunology letters 2001;77(1):25-30.
2001: Yashusi Adachi; Urara Kohdera; Kikuya Sugiura; A Shinohara; Muneo Inaba; Kazuya Ikebukuro; Haruki Oyaizu; H Genba; Yohnosuke Kobayashi; Susumu Ikehara
A 4-month-old infant showing anemia, granulocytopenia and thrombocytopenia probably due to autoreactive IgG.
Pediatrics international : official journal of the Japan Pediatric Society 2001;43(1):91-4.
2001: Yashusi Adachi; Ryoji Yasumizu; F Hashimoto; Y Otsuka; Akiharu Okamura; Y Kato; Haruki Oyaizu; Kazuya Ikebukuro; Shirou Fukuhara; Y Nakai; Susumu Ikehara
An autopsy case of giant cell myocarditis probably due to a non-steroidal anti-inflammatory drug.
Pathology international 2001;51(2):113-7.
2001: Susumu Ikehara
Successful allogeneic bone marrow transplantation. Crucial roles of stromal cells in prevention of graft rejection.
Acta haematologica 2001;105(3):172-8.
2001: Taketoshi Kushida; Muneo Inaba; Hiroko Hisha; Naoya Ichioka; Takashi Esumi; Ryokei Ogawa; Hirokazu Iida; Susumu Ikehara
Crucial role of donor-derived stromal cells in successful treatment for intractable autoimmune diseases in mrl/lpr mice by bmt via portal vein.
Stem cells (Dayton, Ohio) 2001;19(3):226-35.
2001: Tian-Xue Fan; Hiroko Hisha; T N Jin; C Z Yu; Zhe-Xiong Lian; S B Guo; Yun-Ze Cui; B Feng; Guo-Xiang Yang; Qing Li; Susumu Ikehara
Successful allogeneic bone marrow transplantation (BMT) by injection of bone marrow cells via portal vein: stromal cells as BMT-facilitating cells.
Stem cells (Dayton, Ohio) 2001;19(2):144-50.
2001: Kikuya Sugiura; Hiroko Hisha; J Ishikawa; Y Adachi; S Taketani; S Lee; Takashi Nagahama; Susumu Ikehara
Major histocompatibility complex restriction between hematopoietic stem cells and stromal cells in vitro.
Stem cells (Dayton, Ohio) 2001;19(1):46-58.
2000: S Lee; H Iwai; Kikuya Sugiura; K Takeuchi; Taketoshi Kushida; K Tomoda; Muneo Inaba; Toshio Yamashita; Susumu Ikehara
Prevention of autoimmune hearing loss in MRL/lpr mice by bone marrow transplantation.
Bone marrow transplantation 2000;26(8):887-92.
2000: Ryoji Yasumizu; S Miyawaki; M Koba; M Kondoh-Tanaka; Yasuo Amoh; N Nishio; Y Yamamoto; H Watanabe; Susumu Ikehara
Pathology of ALY mice: congenital immunodeficiency with lymph node and Peyer's patch defects.
Immunobiology 2000;202(3):213-25.
2000: Y Li; Hiroko Hisha; M Inaba; Zhe-Xiong Lian; C Yu; M Kawamura; Y Yamamoto; N Nishio; Junko Toki; Hongxue Fan; Susumu Ikehara
Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts: A role of stromal cells in positive selection.
Experimental hematology 2000;28(8):950-60.
2000: Shin-ichiro Kitajiri; Naoki Hosaka; Keisaku Tabuchi; Harukazu Hiraumi; Hidekazu Nogaki; S Tatsumi; Junko Toki; Susumu Ikehara
A case report of FSH-producing nasal ectopic pituitary adenoma extending to the frontal cranial fossa.
Archives of otolaryngology--head & neck surgery 2000;126(6):782-4.
2000: K Takase; Yashusi Adachi; Ryoji Yasumizu; Junko Toki; Tienan Jin; Haruki Oyaizu; Susumu Ikehara; K Takase; T Kinoshita; Akiharu Okamura; M Wakamatsu; Kyoichi Inoue; Y Kato
[An autopsy case of thymic carcinoma producing various tumor markers and the examination of 222 autopsy cases of thymic malignant tumor in Japan].
Kyobu geka. The Japanese journal of thoracic surgery 2000;53(6):450-6.
2000: Kazuya Ikebukuro; Yashusi Adachi; Junko Toki; Shigeru Taketani; R Tokunaga; K Hioki; Susumu Ikehara
Morphological change, loss of deltapsi(m) and activation of caspases upon apoptosis of colorectal adenocarcinoma induced by 5-FU.
Cancer letters 2000;153(1-2):101-8.
2000: A Sugihara; Muneo Inaba; SI Mori; Shigeru Taketani; Yashusi Adachi; Hiroko Hisha; K Inaba; Junko Toki; T Horio; M Eric Gershwin; Susumu Ikehara
Differentiation from thymic B cell progenitors to mature B cells in vitro.
Immunobiology 2000;201(5):515-26.
2000: R Miyazaki; H Ogata; T Iguchi; S Sogo; T Kushida; T Ito; Muneo Inaba; Susumu Ikehara; Yohnosuke Kobayashi
Comparative analyses of megakaryocytes derived from cord blood and bone marrow.
British journal of haematology 2000;108(3):602-9.
2000: H Morita; K Sugiura; Takashi Nagahama; Yohei Sakakura; W Tu; Michio Oda; T Inoue; H Inui; S Taketani; Yasuo Kamiyama; Susumu Ikehara
Acceptance of skin xenografts (from guinea pig to mice) by portal venous and intravenous injections of donor hematolymphoid cells.
Transplantation proceedings 2000;32(2):293-4.
2000: Taketoshi Kushida; Muneo Inaba; K Takeuchi; Kikuya Sugiura; Ryokei Ogawa; Susumu Ikehara
Treatment of intractable autoimmune diseases in MRL/lpr mice using a new strategy for allogeneic bone marrow transplantation.
Blood 2000;95(5):1862-8.
2000: Susumu Ikehara
Pluripotent hemopoietic stem cells in mice and humans.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 2000;223(2):149-55.
2000: Taketoshi Kushida; Muneo Inaba; Kazuya Ikebukuro; T Ngahama; Haruki Oyaizu; S Lee; Tomoki Ito; Naoya Ichioka; Hiroko Hisha; Kikuya Sugiura; S Miyashima; Naohide Ageyama; F Ono; Hirokazu Iida; Ryokei Ogawa; Susumu Ikehara
A new method for bone marrow cell harvesting.
Stem cells (Dayton, Ohio) 2000;18(6):453-6.
2000: B Feng; Muneo Inaba; Zhe-Xiong Lian; Yunze Cui; Junko Toki; Tomoki Ito; Tienan Jin; Tianxue Fan; Guoxiang Yang; C Yu; Taketoshi Kushida; Susumu Ikehara
Development of mouse dendritic cells from lineage-negative c-kit(low) pluripotent hemopoietic stem cells in vitro.
Stem cells (Dayton, Ohio) 2000;18(1):53-60.
1999: N Taguchi; Y Hashimoto; Mitsuru Naiki; A G Farr; RL Boyd; Aftab A Ansari; Leonard D Shultz; Brian L Kotzin; Kenneth Dorshkind; Susumu Ikehara; M Eric Gershwin
Abnormal thymic expression of epithelial cell adhesion molecule (EP-CAM) in New Zealand Black (NZB) mice.
Journal of autoimmunity 1999;13(4):393-404.
1999: Yashusi Adachi; Shigeru Taketani; Haruki Oyaizu; Kazuya Ikebukuro; R Tokunaga; Susumu Ikehara
Apoptosis of colorectal adenocarcinoma induced by 5-FU and/or IFN-gamma through caspase 3 and caspase 8.
International journal of oncology 1999;15(6):1191-6.
1999: Ryoji Yasumizu; Yasuo Amoh; Susumu Ikehara
Identification of thorotrast by gamma-spectrometry and simplified autoradiography in pathological specimens.
Pathology international 1999;49(8):737-41.
1999: T Ito; Muneo Inaba; K Inaba; Junko Toki; S Sogo; T Iguchi; Yashusi Adachi; K Yamaguchi; R Amakawa; Jenny Valladeau; Sem Saeland; Shirou Fukuhara; Susumu Ikehara
A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1409-19.
1999: Haruki Oyaizu; Yashusi Adachi; Shigeru Taketani; R Tokunaga; Shirou Fukuhara; Susumu Ikehara
A crucial role of caspase 3 and caspase 8 in paclitaxel-induced apoptosis.
Molecular cell biology research communications : MCBRC 1999;2(1):36-41.
1999: Tienan Jin; Kikuya Sugiura; J Ishikawa; S Lee; H Morita; T Nagahama; Susumu Ikehara
Persistent tolerance induced after portal venous injection of allogeneic cells plus cyclophosphamide treatment.
Immunobiology 1999;200(2):215-26.
1999: Hatem Sabaawy; Susumu Ikehara; Y Adachi; S Quan; E Feldman; Ram Kancherla; Nader G Abraham; Tauseef Ahmed
Enhancement of 5-fluorouracil cytotoxicity on human colon cancer cells by retrovirus-mediated interferon-alpha gene transfer.
International journal of oncology 1999;14(6):1143-51.
1999: H Watanabe; Muneo Inaba; Yashusi Adachi; Kikuya Sugiura; Hiroko Hisha; T Iguchi; Tomoki Ito; Ryoji Yasumizu; K Inaba; Toshio Yamashita; Susumu Ikehara
Experimental autoimmune thyroiditis induced by thyroglobulin-pulsed dendritic cells.
Autoimmunity 1999;31(4):273-82.
1999: A Sugihara; Yashusi Adachi; Muneo Inaba; Hiroko Hisha; Kikuya Sugiura; S Miyashima; Yasuo Amoh; Shigeru Taketani; Haruki Oyaizu; Kazuya Ikebukuro; M Kawamura; H Genba; T Horio; Susumu Ikehara
Age-dependent abnormalities of hematopoietic stem cells in (NZW x BXSB)F1 mice.
Stem cells (Dayton, Ohio) 1999;17(6):357-65.
1999: Zhe-Xiong Lian; B Feng; Kikuya Sugiura; Muneo Inaba; C Yu; Tienan Jin; Tianxue Fan; Yunze Cui; Ryoji Yasumizu; Junko Toki; Yashusi Adachi; Hiroko Hisha; Susumu Ikehara
c-kit
Stem cells (Dayton, Ohio) 1999;17(1):39-44.

1999: Susumu Ikehara
New strategies for allogeneic bone marrow transplantation and organ allografts.
Acta haematologica 1999;101(2):68-77.
1999: T Iguchi; S Sogo; Hiroko Hisha; Shigeru Taketani; Yashusi Adachi; R Miyazaki; H Ogata; S Masuda; R Sasaki; M Ito; Shirou Fukuhara; Susumu Ikehara
HGF activates signal transduction from EPO receptor on human cord blood CD34+/CD45+ cells.
Stem cells (Dayton, Ohio) 1999;17(2):82-91.
1998: Yashusi Adachi; Yohnosuke Kobayashi; H Ida; Ryoji Yasumizu; Akiharu Okamura; H Kayatani; N Teranishi; Muneo Inaba; A Sugihara; H Genba; Y Eto; Susumu Ikehara
An autopsy case of fetal Gaucher disease.
Acta paediatrica Japonica; Overseas edition 1998;40(4):374-7.
1998: K Takeuchi; Muneo Inaba; S Miyashima; Ryokei Ogawa; Susumu Ikehara
A new strategy for treatment of autoimmune diseases in chimeric resistant MRL/lpr mice.
Blood 1998;91(12):4616-23.
1998: H Morita; K Sugiura; Muneo Inaba; Tienan Jin; J Ishikawa; Zhe-Xiong Lian; Yashusi Adachi; S Sogo; K Yamanishi; H Taki; M Adachi; T Noumi; Y Kamiyama; R A Good; Susumu Ikehara
A strategy for organ allografts without using immunosuppressants or irradiation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6947-52.
1998: Hiroshi Iwai; Koichi Tomoda; N Hosaka; S Miyashima; Y Suzuka; H Ikeda; Shinryu Lee; Muneo Inaba; Susumu Ikehara; Toshio Yamashita
Induction of immune-mediated hearing loss in SCID mice by injection of MRL/lpr mouse spleen cells.
Hearing research 1998;117(1-2):173-7.
1998: Yashusi Adachi; Muneo Inaba; A Sugihara; M Koshiji; Kikuya Sugiura; Yasuo Amoh; SI Mori; T Kamiya; H Genba; Susumu Ikehara
Effects of administration of monoclonal antibodies (anti-CD4 or anti-CD8) on the development of autoimmune diseases in (NZW x BXSB)F1 mice.
Immunobiology 1998;198(4):451-64.
1998: Susumu Ikehara
Bone marrow transplantation for autoimmune diseases.
Acta haematologica 1998;99(3):116-32.
1998: Kikuya Sugiura; Savita Pahwa; Y Yamamoto; K Borisov; Rajendra Pahwa; R P Nelson; J Ishikawa; T Iguchi; Naoki Oyaizu; R A Good; Susumu Ikehara
Characterization of natural suppressor cells in human bone marrow.
Stem cells (Dayton, Ohio) 1998;16(2):99-106.
1998: C Z Yu; Hiroko Hisha; Yongan Li; Zhe-Xiong Lian; T Nishino; Junko Toki; Yashusi Adachi; Muneo Inaba; Tian-Xue Fan; Tienan Jin; T Iguchi; S Sogo; Naoki Hosaka; T H Song; J Xing; Susumu Ikehara
Stimulatory effects of hepatocyte growth factor on hemopoiesis of SCF/c-kit system-deficient mice.
Stem cells (Dayton, Ohio) 1998;16(1):66-77.
1998: M Koshiji; Yashusi Adachi; S Sogo; Shigeru Taketani; Naoki Oyaizu; S Than; Muneo Inaba; S Phawa; K Hioki; Susumu Ikehara
Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression.
Clinical and experimental immunology 1998;111(1):211-8.
1997: M Koshiji; Yashusi Adachi; Shigeru Taketani; K Takeuchi; K Hioki; Susumu Ikehara
Mechanisms underlying apoptosis induced by combination of 5-fluorouracil and interferon-gamma.
Biochemical and biophysical research communications 1997;240(2):376-81.
1997: Kikuya Sugiura; K Kato; F Hashimoto; Tienan Jin; Yasuo Amoh; Y Yamamoto; H Morita; K Okumura; Susumu Ikehara
Induction of donor-specific T cell anergy by portal venous injection of allogeneic cells.
Immunobiology 1997;197(5):460-77.
1997: Hiroko Hisha; Haruki Yamada; M H Sakurai; Hiroaki Kiyohara; Y Li; C Yu; N Takemoto; H Kawamura; K Yamaura; S Shinohara; Y Komatsu; Masaki Aburada; Susumu Ikehara
Isolation and identification of hematopoietic stem cell-stimulating substances from Kampo (Japanese herbal) medicine, Juzen-taiho-to.
Blood 1997;90(3):1022-30.
1997: Yasuo Amoh; Ryoji Yasumizu; Y Yamamoto; Junko Toki; N Nishio; Yashusi Adachi; H Watanabe; Kyoichi Inoue; Susumu Ikehara
The appearance of unusual phenotypic cells (CD4+ Mac-1+ class II+) in the liver of (NZW x BXSB)F1 mice is possibly an animal model for autoimmune hepatitis.
Immunobiology 1997;197(1):31-43.
1997: H Hayashi; Junko Toki; Zhe-Xiong Lian; Kyoichi Inoue; Susumu Ikehara
Analyses of extrathymic T cell differentiation in nu/nu mice by grafting embryonal organs.
Immunobiology 1997;197(1):1-15.
1997: SI Mori; Muneo Inaba; A Sugihara; Shigeru Taketani; H Doi; Y Fukuba; Y Yamamoto; Yashusi Adachi; K Inaba; Shirou Fukuhara; Susumu Ikehara
Presence of B cell progenitors in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4193-9.
1997: H Doi; Muneo Inaba; Y Yamamoto; Shigeru Taketani; SI Mori; A Sugihara; H Ogata; Junko Toki; Hiroko Hisha; K Inaba; S Sogo; M Adachi; Tadashi Matsuda; R A Good; Susumu Ikehara
Pluripotent hemopoietic stem cells are c-kit
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2513-7.

1997: Kikuya Sugiura; Muneo Inaba; Hiroko Hisha; K Borisov; E E Sardiña; R A Good; Susumu Ikehara
Requirement of major histocompatibility complex-compatible microenvironment for spleen colony formation (CFU-S on day 12 but not on day 8).
Stem cells (Dayton, Ohio) 1997;15(6):461-8.
1997: Zhe-Xiong Lian; Junko Toki; C Yu; H Hayashi; Ryoji Yasumizu; Kikuya Sugiura; Tienan Jin; Muneo Inaba; Hiroko Hisha; Yongan Li; W Yu; Hongxue Fan; Susumu Ikehara
Intrathymically injected hemopoietic stem cells can differentiate into all lineage cells in the thymus: differences between c-kit+ cells and c-kit < low cells.
Stem cells (Dayton, Ohio) 1997;15(6):430-6.
1997: S Sogo; Muneo Inaba; H Ogata; Hiroko Hisha; Yashusi Adachi; SI Mori; Junko Toki; K Yamanishi; H Kanzaki; M Adachi; Susumu Ikehara
Induction of c-kit molecules on human CD34+/c-kit < low cells: evidence for CD34+/c-kit < low cells as primitive hematopoietic stem cells.
Stem cells (Dayton, Ohio) 1997;15(6):420-9.
1997: M Kawamura; Hiroko Hisha; Yongan Li; Shirou Fukuhara; Susumu Ikehara
Distinct qualitative differences between normal and abnormal hemopoietic stem cells in vivo and in vitro.
Stem cells (Dayton, Ohio) 1997;15(1):56-62.
1997: F Hashimoto; Kikuya Sugiura; K Inoue; Susumu Ikehara
Major histocompatibility complex restriction between hematopoietic stem cells and stromal cells in vivo.
Blood 1997;89(1):49-54.
1996: Susumu Ikehara
Role of hepatocyte growth factor in hemopoiesis.
Leukemia & lymphoma 1996;23(3-4):297-303.
1996: N Nishio; Hiroko Hisha; H Ogata; Muneo Inaba; Y Yamamoto; Yasuo Amoh; Ryoji Yasumizu; K Hanada; H Hamada; Susumu Ikehara
Changes in markers, receptors and adhesion molecules expressed on murine hemopoietic stem cells after a single injection of 5-fluorouracil.
Stem cells (Dayton, Ohio) 1996;14(5):584-91.
1996: N Hosaka; M Nose; M Kyogoku; N Nagata; S Miyashima; R A Good; Susumu Ikehara
Thymus transplantation, a critical factor for correction of autoimmune disease in aging MRL/+mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8558-62.
1996: Y Yamamoto; Ryoji Yasumizu; Y Amou; N Watanabe; N Nishio; Junko Toki; S Fukuhara; Susumu Ikehara
Characterization of peripheral blood stem cells in mice.
Blood 1996;88(2):445-54.
1996: A Sugihara; Yashusi Adachi; Muneo Inaba; K Inaba; S Miyashima; Y Yamamoto; H Hayashi; H Genba; T Horio; Susumu Ikehara
Expression of CD45-restricted form B in (NZW x BXSB) F1 and MRL/Mp-lpr/lpr mice.
Autoimmunity 1996;24(4):237-46.
1996: Susumu Ikehara
Bone marrow transplantation as a strategy for the treatment of autoimmune-linked renal diseases.
Renal failure 1996;18(1):1-18.
1996: S Miyashima; N Nagata; T Nakagawa; N Hosaka; K Takeuchi; R Ogawa; Susumu Ikehara
Prevention of lpr-graft-versus-host disease and transfer of autoimmune diseases in normal C57BL/6 mice by transplantation of bone marrow cells plus bones (stromal cells) from MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(1):79-84.
1995: F Takao; Ryoji Yasumizu; S Than; Y Ohnishi-Inoue; K Sigiura; Muneo Inaba; Susumu Ikehara
Development of insulin-dependent diabetes mellitus in [(NOD + BALB/c) --> NOD] mixed allogeneic bone marrow chimeras.
Immunobiology 1995;194(4-5):376-89.
1995: T Nishino; Hiroko Hisha; N Nishino; M Adachi; Susumu Ikehara
Hepatocyte growth factor as a hematopoietic regulator.
Blood 1995;85(11):3093-100.
1995: H Haruna; Muneo Inaba; K Inaba; Shigeru Taketani; Kikuya Sugiura; Y Fukuba; H Doi; Junko Toki; R Tokunaga; Susumu Ikehara
Abnormalities of B cells and dendritic cells in SAMP1 mice.
European journal of immunology 1995;25(5):1319-25.
1995: Hiroko Hisha; T Nishino; M Kawamura; S Adachi; Susumu Ikehara
Successful bone marrow transplantation by bone grafts in chimeric-resistant combination.
Experimental hematology 1995;23(4):347-52.
1995: N Nishioka; Junko Toki; Kikuya Sugiura; S Than; Ryoji Yasumizu; Muneo Inaba; M Nishimura; Susumu Ikehara
Repair mechanism of lupus nephritis in (NZB x NZW)F1 mice by allogeneic bone marrow transplantation.
Immunobiology 1995;192(5):279-96.
1994: Susumu Ikehara
Intractable diseases and bone marrow transplantation.
Pathology international 1994;44(12):817-26.
1994: N Nagata; S Miyashima; Shigeru Taketani; Junko Toki; N Hosaka; T Tomita; H Fujishima; R Tokunaga; Susumu Ikehara
A murine nephritogenic monoclonal antibody binds to both single-stranded deoxyribonucleic acid and glomerulus.
Laboratory investigation; a journal of technical methods and pathology 1994;71(5):765-72.
1994: F Hashimoto; Kikuya Sugiura; K Inoue; Susumu Ikehara
Enhancing effects of cyclosporin A on hematopoietic progenitors: possible role of CD8+ T cells as negative regulators.
Experimental hematology 1994;22(10):947-53.
1994: Y Zhang; Ryoji Yasumizu; Kikuya Sugiura; F Hashimoto; Yasuo Amoh; Zhe-Xiong Lian; N Nishio; Susumu Ikehara
Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: possible explanation for the mechanism of tolerance induction by portal vein injection.
European journal of immunology 1994;24(7):1558-65.
1994: N Hosaka; N Nagata; S Miyashima; Susumu Ikehara
Attenuation of lpr-graft-versus-host disease (GVHD) in MRL/lpr spleen cell-injected SCID mice by in vivo treatment with anti-V beta 8.1,2 monoclonal antibody.
Clinical and experimental immunology 1994;96(3):500-7.
1994: Susumu Ikehara; M Inaba; Ryoji Yasumizu; N Nagata; Junko Toki; Hiroko Hisha; Kikuya Sugiura; Naoki Oyaizu; M Kawamura; S Than
Autoimmune diseases as stem cell disorders.
The Tohoku journal of experimental medicine 1994;173(1):141-55.
1994: T Ishida; Muneo Inaba; Hiroko Hisha; Kikuya Sugiura; Yashusi Adachi; N Nagata; R Ogawa; R A Good; Susumu Ikehara
Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation. Complete prevention of recurrence of autoimmune diseases in MRL/MP-Ipr/Ipr mice by transplantation of bone marrow plus bones (stromal cells) from the same donor.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):3119-27.
1994: Ryoji Yasumizu; Junko Toki; H Asou; T Nishino; Y Komatsu; Susumu Ikehara
Production of hematopoietic stem cell-chemotactic factor by bone marrow stromal cells.
Blood 1994;83(4):964-71.
1994: N Nagata; Shigeru Taketani; T Nakagawa; N Hosaka; Hiroko Hisha; R Tokunaga; Susumu Ikehara
Increased cell surface expression of a newly identified heterodimer on activated blastic T cells.
Cellular immunology 1994;153(2):516-26.
1994: Y Fukuba; Muneo Inaba; S Taketani; Y Hitoshi; Yashusi Adachi; R Tokunaga; K Inaba; K Takatsu; Susumu Ikehara
Functional analysis of thymic B cells.
Immunobiology 1994;190(1-2):150-63.
1994: H Iwai; N K Day; N Hamada; Muneo Inaba; Susumu Ikehara; R A Good
Bone marrow transplantation therapy using resistant donors for retrovirus-induced leukaemia in mice.
Clinical and experimental immunology 1994;95(1):135-40.
1994: N Hosaka; N Nagata; T Nakagawa; S Miyashima; Ryoji Yasumizu; Susumu Ikehara
Analyses of lpr-GVHD by adoptive transfer experiments using MRL/lpr-Thy-1.1 congenic mice.
Autoimmunity 1994;17(3):217-24.
1993: Yashusi Adachi; Muneo Inaba; K Inaba; S Than; Y Kobayashi; Susumu Ikehara
Analyses of thymic abnormalities in autoimmune-prone (NZW x BXSB) F1 mice.
Immunobiology 1993;188(4-5):340-54.
1993: H Kitagawa; Junko Toki; Muneo Inaba; Kikuya Sugiura; R Ogawa; Susumu Ikehara
Analyses of origin of synovial cells and repairing mechanisms of arthritis by allogeneic bone marrow transplantation.
Immunobiology 1993;188(1-2):99-112.
1993: N Nagata; Shigeru Taketani; Yashusi Adachi; N Hosaka; S Miyashima; R Tokunaga; Susumu Ikehara
A monoclonal antibody reactive with a glycophosphatidylinositol-anchored molecule on T cells defines CD4+ T cell subsets.
European journal of immunology 1993;23(5):1193-6.
1993: N Nagata; T Saito; Junko Toki; Susumu Ikehara
Transplantability and MHC antigen expression of tumor mast cells.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1993;45(1):29-34.
1993: T Nakagawa; N Nagata; N Hosaka; R Ogawa; K Nakamura; Susumu Ikehara
Prevention of autoimmune inflammatory polyarthritis in male New Zealand black/KN mice by transplantation of bone marrow cells plus bone (stromal cells).
Arthritis and rheumatism 1993;36(2):263-8.
1993: Yashusi Adachi; Muneo Inaba; K Inaba; N Nagata; Y Kobayashi; Susumu Ikehara
Functional analyses of B cells in (NZW x BXSB) F1 mice.
Autoimmunity 1993;15(2):99-105.
1992: Y Ohnishi-Inoue; Ryoji Yasumizu; Kikuya Sugiura; N Nagata; H Fan; Naoki Oyaizu; Muneo Inaba; Junko Toki; Susumu Ikehara
Functional analyses of lpr gene in MRL/Mp-lpr/lpr mice. Role of lymph node stromal cells in lpr-lymphadenopathy.
Immunobiology 1992;186(5):449-65.
1992: N Nagata; T Nakagawa; N Hosaka; Susumu Ikehara
Auto-MHC class II-reactive T cell line obtained from MRL/+ mice suffering from lpr-GVHD. II. Analyses of functional characteristics of T cell line by in vivo administration.
Immunobiology 1992;186(5):339-50.
1992: S Than; H Ishida; Muneo Inaba; Y Fukuba; Y Seino; M Adachi; H Imura; Susumu Ikehara
Bone marrow transplantation as a strategy for treatment of non-insulin-dependent diabetes mellitus in KK-Ay mice.
The Journal of experimental medicine 1992;176(4):1233-8.
1992: Junko Toki; W Miyazaki; Muneo Inaba; S Saigo; T Nishino; Y Fukuba; R A Good; Susumu Ikehara
Effects of K-76COOH (MX-1) on immune response: induction of suppressor T-cells by MX-1.
International journal of immunopharmacology 1992;14(6):1093-8.
1992: H Ogata; S Taniguchi; Muneo Inaba; M Sugawara; Y Ohta; K Inaba; K J Mori; Susumu Ikehara
Separation of hematopoietic stem cells into two populations and their characterization.
Blood 1992;80(1):91-5.
1992: S Than; Muneo Inaba; K Inaba; Y Fukuba; Yashusi Adachi; Susumu Ikehara
Origin of thymic and peritoneal Ly-1 B cells.
European journal of immunology 1992;22(5):1299-303.
1992: Susumu Ikehara; H Kawamura; Y Komatsu; Haruki Yamada; Hiroko Hisha; Ryoji Yasumizu; Y Ohnishi-Inoue; Hiroaki Kiyohara; M Hirano; Masaki Aburada
Effects of medicinal plants on hemopoietic cells.
Advances in experimental medicine and biology 1992;319():319-30.
1991: Kikuya Sugiura; Ryoji Yasumizu; H Iwai; Muneo Inaba; Junko Toki; M Ogura; I Hara; R A Good; Susumu Ikehara
Long-term immunologic tolerance induction in chimeric mice after bone marrow transplantation across major histocompatibility barriers: persistent or redeveloping immunologic responsiveness after prolonged survival.
Thymus 1991;18(3):137-53.
1991: T Nakagawa; N Nagata; N Hosaka; Muneo Inaba; Ryoji Yasumizu; R Ogawa; Susumu Ikehara
Analyses of acute graft-versus-host-like reaction in [MRL/lpr----MRL/+] chimeric mice using MRL/lpr-Thy-1. 1 congenic mice.
Cellular immunology 1991;137(1):189-99.
1991: H Kitagawa; Junko Toki; T Morimoto; T Okumura; K Saitoh; H Higashino; T Horii; Y Kobayashi; Susumu Ikehara
An autopsy case of I-cell disease. Ultrastructural and biochemical analyses.
American journal of clinical pathology 1991;96(2):262-6.
1991: Muneo Inaba; K Inaba; M Hosono; T Kumamoto; T Ishida; S Muramatsu; T Masuda; Susumu Ikehara
Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells.
The Journal of experimental medicine 1991;173(3):549-59.
1990: Susumu Ikehara; M Kawamura; F Takao; Muneo Inaba; Ryoji Yasumizu; S Than; Hiroko Hisha; Kikuya Sugiura; Y Koide; T O Yoshida
Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8341-4.
1990: N Nagata; Ryoji Yasumizu; Y Ohnishi; T Nakagawa; Muneo Inaba; Susumu Ikehara
Auto-MHC class II-reactive T cell line obtained from MRL/+mice suffering from "lpr-GVHD". I. Characterization of surface phenotypes, specificities and functions in vitro.
Immunobiology 1990;181(4-5):367-78.
1990: R Yasumizu; S Miyawaki; Kikuya Sugiura; T Nakamura; Y Ohnishi; R A Good; Y Hamashima; Susumu Ikehara
Allogeneic bone marrow-plus-liver transplantation in the C57BL/KsJ spm/spm mouse, an animal model of Niemann-Pick disease.
Transplantation 1990;49(4):759-64.
1990: H X Fan; Ryoji Yasumizu; Kikuya Sugiura; N Oyaizu; Y Ohnishi; F Takao; Muneo Inaba; J Liu; Susumu Ikehara
Histogenesis of hemopoietic bone marrow in adult mice.
Experimental hematology 1990;18(3):159-66.
1990: Y Ohnishi; Ryoji Yasumizu; H X Fan; J Liu; F Takao-Liu; Y Komatsu; E Hosoya; R A Good; Susumu Ikehara
Effects of juzen-taiho-toh (TJ-48), a traditional Oriental medicine, on hematopoietic recovery from radiation injury in mice.
Experimental hematology 1990;18(1):18-22.
1990: Muneo Inaba; K Inaba; Yashusi Adachi; K Nango; H Ogata; S Muramatsu; Susumu Ikehara
Functional analyses of thymic CD5+ B cells. Responsiveness to major histocompatibility complex class II-restricted T blasts but not to lipopolysaccharide or anti-IgM plus interleukin 4.
The Journal of experimental medicine 1990;171(1):321-6.
1989: Susumu Ikehara; Ryoji Yasumizu; Muneo Inaba; S Izui; K Hayakawa; K Sekita; Junko Toki; Kikuya Sugiura; H Iwai; T Nakamura
Long-term observations of autoimmune-prone mice treated for autoimmune disease by allogeneic bone marrow transplantation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3306-10.
1989: H Iwai; S Kuma; M M Inaba; R A Good; T Yamashita; T Kumazawa; Susumu Ikehara
Acceptance of murine thyroid allografts by pretreatment of anti-Ia antibody or anti-dendritic cell antibody in vitro.
Transplantation 1989;47(1):45-9.
1988: M Miyama-Inaba; S Kuma; K Inaba; H Ogata; H Iwai; Ryoji Yasumizu; S Muramatsu; R M Steinman; Susumu Ikehara
Unusual phenotype of B cells in the thymus of normal mice.
The Journal of experimental medicine 1988;168(2):811-6.
1988: Kikuya Sugiura; Muneo Inaba; H Ogata; Ryoji Yasumizu; K Inaba; R A Good; Susumu Ikehara
Wheat germ agglutinin-positive cells in a stem cell-enriched fraction of mouse bone marrow have potent natural suppressor activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4824-6.
1987: M Miyama-Inaba; H Ogata; Junko Toki; S Kuma; Kikuya Sugiura; Ryoji Yasumizu; Susumu Ikehara
Isolation of murine pluripotent hemopoietic stem cells in the Go phase.
Biochemical and biophysical research communications 1987;147(2):687-94.

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