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Elena Avdievich

Research Profile

Living Beings

Disorders

Physiology

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Meiosis

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Publications

TOP 3
Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Johanna M M van Oers; Chunfang Zhao; Elena Avdievich; Sergio Roa
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.
Sergio Roa; Elena Avdievich; Jonathan U Peled; Thomas MacCarthy; Uwe Werling; Fei Li Kuang; Rui Kan; Chunfang Zhao; Aviv Bergman; Paula E Cohen; Winfried Edelmann; Matthew D Scharff
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
Ivana Marinovic-Terzic; Atsuko Yoshioka-Yamashita; Hideki Shimodaira; Elena Avdievich; Irina C Hunton; Richard D Kolodner; Winfried Edelmann; Jean Y J Wang
Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.

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All Publications

2012: Richard Chahwan; Winfried Edelmann; Matthew D Scharff; Johanna M M van Oers; Chunfang Zhao; Elena Avdievich; Sergio Roa
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.
The Journal of experimental medicine 2012;209(4):671-8.
2008: Sergio Roa; Elena Avdievich; Jonathan U Peled; Thomas MacCarthy; Uwe Werling; Fei Li Kuang; Rui Kan; Chunfang Zhao; Aviv Bergman; Paula E Cohen; Winfried Edelmann; Matthew D Scharff
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16248-53.
2008: Ivana Marinovic-Terzic; Atsuko Yoshioka-Yamashita; Hideki Shimodaira; Elena Avdievich; Irina C Hunton; Richard D Kolodner; Winfried Edelmann; Jean Y J Wang
Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13993-8.
2008: Elena Avdievich; Cora Reiss; Stefan J Scherer; Yongwei Zhang; Sandra M Maier; Bo Jin; Harry Hou; Andreas Rosenwald; Hubertus Riedmiller; Raju Kucherlapati; Paula E Cohen; Winfried Edelmann; Burkhard Kneitz
Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4247-52.
2008: Rui Kan; Xianfei Sun; Nadine K Kolas; Elena Avdievich; Burkhard Kneitz; Winfried Edelmann; Paula E Cohen
Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway.
Biology of reproduction 2008;78(3):462-71.
2005: Stefan J Scherer; Elena Avdievich; Winfried Edelmann
Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition.
Biochemical Society transactions 2005;33(Pt 4):689-93.
2004: Diana P Lin; Yuxun Wang; Stefan J Scherer; Alan B Clark; Kan Yang; Elena Avdievich; Bo Jin; Uwe Werling; Tchaiko Parris; Naoto Kurihara; Asad Umar; Raju Kucherlapati; Martin Lipkin; Thomas A Kunkel; Winfried Edelmann
An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.
Cancer research 2004;64(2):517-22.
2002: Edmund Wong; Kan Yang; Mari Kuraguchi; Uwe Werling; Elena Avdievich; Kunhua Fan; Melissa Fazzari; Bo Jin; Anthony M C Brown; Martin Lipkin; Winfried Edelmann
Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14937-42.
2001: Mari Kuraguchi; Kan Yang; Edmund Wong; Elena Avdievich; Kunhua Fan; Richard D Kolodner; Martin Lipkin; Anthony M C Brown; Raju Kucherlapati; Winfried Edelmann
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.
Cancer research 2001;61(21):7934-42.
2000: Burkhard Kneitz; Paula E Cohen; Elena Avdievich; Liyin Zhu; Michael F Kane; Harry Hou; Richard D Kolodner; Raju Kucherlapati; Jeffrey W Pollard; Winfried Edelmann
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
Genes & development 2000;14(9):1085-97.
2000: Winfried Edelmann; Asad Umar; Kan Yang; Joerg Heyer; Melanie Haas Kucherlapati; Mariel Lia; Burkhard Kneitz; Elena Avdievich; Kunhua Fan; Edmund Wong; G Crouse; Thomas A Kunkel; Martin Lipkin; Richard D Kolodner; Raju Kucherlapati
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression.
Cancer research 2000;60(4):803-7.