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Jorma Ilonen

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B I Nwaru; Juha Pekkanen; Olli Simell; H-M Takkinen; H Tuomi; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort.
Marcus C de Goffau; Saara Hakala; Taina Härkönen; Hermie J Harmsen; Jorma Ilonen; Mikael Knip; Kristiina Luopajärvi; Laura Orivuori; Terhi Ruohtula; Gjalt W Welling; Outi Vaarala
Fecal microbiota composition differs between children with β-cell autoimmunity and those without.
Hanna Honkanen; Anna-Maija Haapala; Jorma Ilonen; Mikael Knip; Sanna Korpela; Olli H Laitinen; Maija Lappalainen; Sami Oikarinen; Outi Pakkanen; Minna M Pulkki; Tanja Ruokoranta; Olli Simell; Sisko Tauriainen; Riitta Veijola; Tytti Vuorinen; Heikki Hyöty
Human enterovirus 71 strains in the background population and in hospital patients in Finland.

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All Publications

2013: B I Nwaru; Juha Pekkanen; Olli Simell; H-M Takkinen; H Tuomi; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort.
Allergy 2013;68(4):507-16.
2013: Marcus C de Goffau; Saara Hakala; Taina Härkönen; Hermie J Harmsen; Jorma Ilonen; Mikael Knip; Kristiina Luopajärvi; Laura Orivuori; Terhi Ruohtula; Gjalt W Welling; Outi Vaarala
Fecal microbiota composition differs between children with β-cell autoimmunity and those without.
Diabetes 2013;62(4):1238-44.
2013: Hanna Honkanen; Anna-Maija Haapala; Jorma Ilonen; Mikael Knip; Sanna Korpela; Olli H Laitinen; Maija Lappalainen; Sami Oikarinen; Outi Pakkanen; Minna M Pulkki; Tanja Ruokoranta; Olli Simell; Sisko Tauriainen; Riitta Veijola; Tytti Vuorinen; Heikki Hyöty
Human enterovirus 71 strains in the background population and in hospital patients in Finland.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013;56(4):348-53.
2013: Hanna Honkanen; Jorma Ilonen; Mikael Knip; Sami Oikarinen; Pauliina Peltonen; Olli Simell; Riitta Veijola; Heikki Hyöty
Human rhinoviruses including group C are common in stool samples of young Finnish children.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013;56(3):250-4.
2013: Anna Parkkola; Samppa J Ryhänen; Taina Härkönen; Jorma Ilonen; Mikael Knip
Extended family history of type 1 diabetes and phenotype and genotype of newly diagnosed children.
Diabetes care 2013;36(2):348-54.
2013: Bright I Nwaru; Juha Pekkanen; Olli Simell; Hanna-Mari Takkinen; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Anna-Maija Haapala; Heikki Hyöty; Jorma Ilonen; Minna Kaila; Mike Kenward; Juha Kere; Mikael Knip; Riitta Lahesmaa; Onni Niemelä; Suvi M Virtanen
Timing of infant feeding in relation to childhood asthma and allergic diseases.
The Journal of allergy and clinical immunology 2013;131(1):78-86.
2012: Nina Hautala; Jorma Ilonen; Ari Karttunen; Heikki Kauma; Eija Pääkkö; Saara-Mari Rajaniemi; Seppo Rytky; Tarja Sironen; Antti Vaheri; Olli Vainio; Olli Vapalahti; Timo Hautala
Signs of general inflammation and kidney function are associated with the ocular features of acute Puumala hantavirus infection.
Scandinavian journal of infectious diseases 2012;44(12):956-62.
2012: Janne K Nieminen; Harri M Salo; Jukka Vakkila; Nina Ekström; Taina Härkönen; Jorma Ilonen; Mikael Knip; Outi Vaarala
Altered phenotype of peripheral blood dendritic cells in pediatric type 1 diabetes.
Diabetes care 2012;35(11):2303-10.
2012: Johanna Lempainen; Jorma Ilonen
Influence of type 1 diabetes genes on disease progression: similarities and differences between countries.
Current diabetes reports 2012;12(5):447-55.
2012: M Lumia; Päivi Luukkainen; S Niinistö; B I Nwaru; M Prasad; Olli Simell; H-M Takkinen; Heli Tapanainen; Riitta Veijola; Jorma Ilonen; Minna Kaila; Mike Kenward; Mikael Knip; Suvi M Virtanen
Maternal dietary fat and fatty acid intake during lactation and the risk of asthma in the offspring.
Acta paediatrica (Oslo, Norway : 1992) 2012;101(8):e337-43.
2012: Kristiina Luopajärvi; Janne K Nieminen; Hans K Akerblom; Jorma Ilonen; Mikael Knip; Outi Vaarala
Expansion of CD4+CD25+FOXP3+ regulatory T cells in infants of mothers with type 1 diabetes.
Pediatric diabetes 2012;13(5):400-7.
2012: Bright I Nwaru; Olli Simell; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Jorma Ilonen; Minna Kaila; Mikael Knip; Carina Kronberg-Kippilä; Mirka Lumia; Suvi M Virtanen
Maternal intake of fatty acids during pregnancy and allergies in the offspring.
The British journal of nutrition 2012;108(4):720-32.
2012: Aleksandr Peet; Vallo Tillmann; Jorma Ilonen; Mikael Knip; Pille Kool
Birth weight in newborn infants with different diabetes-associated HLA genotypes in three neighbouring countries: Finland, Estonia and Russian Karelia.
Diabetes/metabolism research and reviews 2012;28(5):455-61.
2012: Vilhelmiina Parikka; M Saarinen; Tuula Simell; Riitta Veijola; Heikki Hyöty; Jorma Ilonen; M Knip; Kirsti Näntö-Salonen; Olli Simell
Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk.
Diabetologia 2012;55(7):1926-36.
2012: Outi Vaarala; Suvi M Virtanen; Hans K Akerblom; Taina Härkönen; Jorma Ilonen; Anna-Liisa Järvenpää; Harri Kallioinen; Jorma Komulainen; Matti Koski; Raisa Lounamaa; Jouni Pesola; Tuija Poussa; Terhi Ruohtula; Olli Tossavainen; Mikael Knip
Removal of Bovine Insulin From Cow's Milk Formula and Early Initiation of Beta-Cell Autoimmunity in the FINDIA Pilot Study.
Archives of pediatrics & adolescent medicine 2012;166(7):608-14.
2012: Hanna Viskari; Heini Huhtala; Jorma Ilonen; Mikael Knip; Olli Simell; Heljä-Marja Surcel; Sisko Tauriainen; Riitta Veijola; Heikki Hyöty
Maternal enterovirus infection as a risk factor for type 1 diabetes in the exposed offspring.
Diabetes care 2012;35(6):1328-32.
2012: Pekka Kolehmainen; Marjaleena Koskiniemi; Sami Oikarinen; Olli Simell; Heikki Hyöty; Jorma Ilonen; Mikael Knip; Sisko Tauriainen
Human parechoviruses are frequently detected in stool of healthy Finnish children.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2012;54(2):156-61.
2012: A Lammi; Outi Vaarala; P Arikoski; Tuure Kinnunen; Jorma Ilonen
Increased peripheral blood CD4+ T cell responses to deamidated but not to native gliadin in children with coeliac disease.
Clinical and experimental immunology 2012;168(2):207-14.
2012: Johanna Lempainen; Olli Simell; Riitta Veijola; Robert Hermann; Mikael Knip; Jorma Ilonen
Effect of the PTPN22 and INS risk genotypes on the progression to clinical type 1 diabetes after the initiation of β-cell autoimmunity.
Diabetes 2012;61(4):963-6.
2012: Maijaliisa Erkkola; Jorma Ilonen; Minna Kaila; Mikael Knip; Carina Kronberg-Kippilä; Bright I Nwaru; Olli Simell; Riitta Veijola; Suvi M Virtanen
Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2012;23(2):186-94.
2012: T Oilinki; T Otonkoski; Jorma Ilonen; Mikael Knip; P J Miettinen
Prevalence and characteristics of diabetes among Somali children and adolescents living in Helsinki, Finland.
Pediatric diabetes 2012;13(2):176-80.
2012: Mira Meriluoto; Juha Mykkänen; Olli Ruuskanen; Olli Simell; Satu Simell; Ville Simell; Klaus Hedman; Lea Hedman; Jorma Ilonen; Mikael Knip; Jan Korpelainen; Marjaana Mäkinen; Laura Tanner; Maria Söderlund-Venermo
Association of human bocavirus 1 infection with respiratory disease in childhood follow-up study, Finland.
Emerging infectious diseases 2012;18(2):264-71.
2012: Suvi M Virtanen; Suvi Ahonen; Jorma Ilonen; Mike Kenward; Carina Kronberg-Kippilä; Jaakko Nevalainen; Sari Niinistö; Marja-Leena Ovaskainen; Olli Simell; Hanna-Mari Takkinen; Heli Tapanainen; Liisa Uusitalo; Riitta Veijola; Mikael Knip
Food consumption and advanced β cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes: a nested case-control design.
The American journal of clinical nutrition 2012;95(2):471-8.
2012: J Lempainen; M Mäkelä; Jane Marttila; Olli Simell; Sisko Tauriainen; Outi Vaarala; Riitta Veijola; H Honkanen; Heikki Hyöty; Mikael Knip; Jorma Ilonen
Interaction of enterovirus infection and cow's milk-based formula nutrition in type 1 diabetes-associated autoimmunity.
Diabetes/metabolism research and reviews 2012;28(2):177-85.
2012: Viveka Oling; Helena Reijonen; Olli Simell; Mikael Knip; Jorma Ilonen
Autoantigen-specific memory CD4+ T cells are prevalent early in progression to Type 1 diabetes.
Cellular immunology 2012;273(2):133-9.
2011: Elina Seppälä; Olli Simell; Hanna Viskari; Jorma Ilonen; Mikael Knip; Hanna Honkanen; Sanna Hoppu; Heini Huhtala; Heikki Hyöty
Viral interference induced by live attenuated virus vaccine (OPV) can prevent otitis media.
Vaccine 2011;29(47):8615-8.
2011: Anne Hekkala; Jorma Ilonen; Mikael Knip; Riitta Veijola
Family history of diabetes and distribution of class II HLA genotypes in children with newly diagnosed type 1 diabetes: effect on diabetic ketoacidosis.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(5):813-7.
2011: Marko Sysi-Aho; Abhishek Tripathi; Laura Vähätalo; Laxman Yetukuri; Suvi T Ruohonen; Maria Saarela; Eriika Savontaus; Tuulikki Seppänen-Laakso; Olli Simell; Andrey Ermolov; Peddinti V Gopalacharyulu; Taina Härkönen; Jorma Ilonen; Samuel Kaski; Mikael Knip; Erno Lindfors; Ismo Mattila; Johanna Maukonen; Janne Nikkilä; Matej Orešič
Metabolic regulation in progression to autoimmune diabetes.
PLoS computational biology 2011;7(10):e1002257.
2011: B I Nwaru; Olli Simell; Riitta Veijola; Suvi Ahonen; Maijaliisa Erkkola; Jorma Ilonen; Minna Kaila; Mikael Knip; Carina Kronberg-Kippilä; Suvi M Virtanen
Intake of antioxidants during pregnancy and the risk of allergies and asthma in the offspring.
European journal of clinical nutrition 2011;65(8):937-43.
2011: Suvi M Virtanen; Maijaliisa Erkkola; Jorma Ilonen; Mike Kenward; Carina Kronberg-Kippilä; Juha Nevalainen; M Salmenhaara; Olli Simell; H-M Takkinen; Liisa Uusitalo; Riitta Veijola; Mikael Knip
Early introduction of root vegetables in infancy associated with advanced ß-cell autoimmunity in young children with human leukocyte antigen-conferred susceptibility to Type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2011;28(8):965-71.
2011: Tuula Arkkola; Jorma Ilonen; Susanna Kautiainen; Mike Kenward; Mikael Knip; Juha Nevalainen; Olli Simell; Hanna-Mari Takkinen; Ulla Uusitalo; Riitta Veijola; Suvi M Virtanen
Relationship of maternal weight status and weight gain rate during pregnancy to the development of advanced beta cell autoimmunity in the offspring: a prospective birth cohort study.
Pediatric diabetes 2011;12(5):478-84.
2011: Maijaliisa Erkkola; Jorma Ilonen; Mikael Knip; Carina Kronberg-Kippilä; Pipsa Kyttälä; Jaakko Nevalainen; Olli Simell; Hanna-Mari Takkinen; Riitta Veijola; Suvi M Virtanen
Nutrient intake variability and number of days needed to assess intake in preschool children.
The British journal of nutrition 2011;106(1):130-40.
2011: Samppa J Ryhänen; Taina Härkönen; Heli Siljander; Kirsti Näntö-Salonen; Tuula Simell; Heikki Hyöty; Jorma Ilonen; Riitta Veijola; Olli Simell; Mikael Knip
Impact of intranasal insulin on insulin antibody affinity and isotypes in young children with HLA-conferred susceptibility to type 1 diabetes.
Diabetes care 2011;34(6):1383-8.
2011: Mervi Oikonen; Martin Panelius; Reijo Salonen; Ville Aalto; Juha-Pekka Erälinna; Jorma Ilonen; Mikko Laaksonen; Aimo Salmi
Temporal relationship between environmental influenza A and Epstein-Barr viral infections and high multiple sclerosis relapse occurrence.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(6):672-80.
2011: Anu Mustila; A-M Haapala; Jorma Ilonen; S Järvenpää; Hannu Kautiainen; Markku Korpela; L Laasonen; Marjatta Leirisalo-Repo; R Luukkainen; T Möttönen; Pekka Hannonen
Anti-citrullinated peptide antibodies and the progression of radiographic joint erosions in patients with early rheumatoid arthritis treated with FIN-RACo combination and single disease-modifying antirheumatic drug strategies.
Clinical and experimental rheumatology 2011;29(3):500-5.
2011: Bright I Nwaru; Maijaliisa Erkkola; Suvi Ahonen; Minna Kaila; Mirka Lumia; Marianne Prasad; Anna-Maija Haapala; Carina Kronberg-Kippilä; Riitta Veijola; Jorma Ilonen; Olli Simell; Mikael Knip; Suvi M Virtanen
Maternal diet during lactation and allergic sensitization in the offspring at age of 5.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2011;22(3):334-41.
2011: M Prasad; H-M Takkinen; J Nevalainen; M-L Ovaskainen; Georg Alfthan; Liisa Uusitalo; Mike Kenward; Riitta Veijola; Olli Simell; Jorma Ilonen; Mikael Knip; Suvi M Virtanen
Are serum α- and β-carotene concentrations associated with the development of advanced beta-cell autoimmunity in children with increased genetic susceptibility to type 1 diabetes?
Diabetes & metabolism 2011;37(2):162-7.
2011: Suvi M Virtanen; Liisa Uusitalo; Mike Kenward; Juha Nevalainen; Ulla Uusitalo; Carina Kronberg-Kippilä; M-L Ovaskainen; T Arkkola; S Niinistö; Timo Hakulinen; Suvi Ahonen; Olli Simell; Jorma Ilonen; Riitta Veijola; Mikael Knip
Maternal food consumption during pregnancy and risk of advanced β-cell autoimmunity in the offspring.
Pediatric diabetes 2011;12(2):95-9.
2011: Hans K Akerblom; J Krischer; Suvi M Virtanen; C Berseth; D Becker; J Dupré; Jorma Ilonen; M Trucco; Erkki Savilahti; K Koski; E Pajakkala; M Fransiscus; G Lough; B Bradley; M Koski; Mikael Knip
The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up.
Diabetologia 2011;54(3):627-33.
2011: Christopher T Brown; George Casella; David B Crabb; Austin G Davis-Richardson; Jennifer C Drew; Kelsey A Gano; Adriana Giongo; Heikki Hyöty; Jorma Ilonen; Mikael Knip; Nabanita Mukherjee; Josef Neu; Desmond Schatz; Olli Simell; Tuula Simell; Riitta Veijola; clive wasserfall; Mark A Atkinson; Eric W Triplett
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.
PloS one 2011;6(10):e25792.
2011: Maija Wessman; Carol Forsblom; Per-Henrik Groop; Samy HADJADJ; Tero Hiekkalinna; Jorma Ilonen; Mari A Kaunisto; Michel Marre; Alexander P Maxwell; Maija Parkkonen; Hans-Henrik Parving; Leena Peltonen; Riitta Sallinen; Jenny Söderlund; Lise Tarnow
Novel susceptibility locus at 22q11 for diabetic nephropathy in type 1 diabetes.
PloS one 2011;6(9):e24053.
2011: Sami Oikarinen; Mika Martiskainen; Sisko Tauriainen; Heini Huhtala; Jorma Ilonen; Riitta Veijola; Olli Simell; Mikael Knip; Heikki Hyöty
Enterovirus RNA in blood is linked to the development of type 1 diabetes.
Diabetes 2011;60(1):276-9.
2011: Adriana Giongo; Kelsey A Gano; David B Crabb; Nabanita Mukherjee; Luis L Novelo; George Casella; Jennifer C Drew; Jorma Ilonen; Mikael Knip; Heikki Hyöty; Riitta Veijola; Tuula Simell; Olli Simell; Josef Neu; clive wasserfall; Desmond Schatz; Mark A Atkinson; Eric W Triplett
Toward defining the autoimmune microbiome for type 1 diabetes.
The ISME journal 2011;5(1):82-91.
2010: Kati Lipponen; Zsofia Gombos; Minna Kiviniemi; Heli Siljander; Johanna Lempainen; Robert Hermann; Riitta Veijola; Olli Simell; Mikael Knip; Jorma Ilonen
Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes.
Diabetes 2010;59(12):3253-6.
2010: Viveka Oling; Kelly Geubtner; Jorma Ilonen; Helena Reijonen
A low antigen dose selectively promotes expansion of high-avidity autoreactive T cells with distinct phenotypic characteristics: a study of human autoreactive CD4+T cells specific for GAD65.
Autoimmunity 2010;43(8):573-82.
2010: Mikael Knip; Suvi M Virtanen; Karri Seppä; Jorma Ilonen; Erkki Savilahti; Outi Vaarala; Antti Reunanen; Kari Teramo; Anu-Maaria Hämäläinen; Johanna Paronen; Hans-Michael Dosch; Timo Hakulinen; Hans K Akerblom
Dietary intervention in infancy and later signs of beta-cell autoimmunity.
The New England journal of medicine 2010;363(20):1900-8.
2010: J Tuokkola; Minna Kaila; Carina Kronberg-Kippilä; H K Sinkko; Timo Klaukka; Pirjo Pietinen; Riitta Veijola; Olli Simell; Jorma Ilonen; Mikael Knip; Suvi M Virtanen
Cow's milk allergy in children: adherence to a therapeutic elimination diet and reintroduction of milk into the diet.
European journal of clinical nutrition 2010;64(10):1080-5.
2010: Jorma Ilonen; Robert Hermann
Novel gene associations in type 1 diabetes.
Current diabetes reports 2010;10(5):338-44.
2010: Jarno Honkanen; Janne K Nieminen; Ru Gao; Kristiina Luopajarvi; Harri M Salo; Jorma Ilonen; Mikael Knip; Timo Otonkoski; Outi Vaarala
IL-17 immunity in human type 1 diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(3):1959-67.
2010: L Marjamäki; S Niinistö; Mike Kenward; Liisa Uusitalo; Ulla Uusitalo; M-L Ovaskainen; Carina Kronberg-Kippilä; Olli Simell; Riitta Veijola; Jorma Ilonen; Mikael Knip; Suvi M Virtanen
Maternal intake of vitamin D during pregnancy and risk of advanced beta cell autoimmunity and type 1 diabetes in offspring.
Diabetologia 2010;53(8):1599-607.
2010: Laura L Elo; Juha Mykkänen; Tuomas Nikula; Henna Järvenpää; Satu Simell; Tero Aittokallio; Heikki Hyöty; Jorma Ilonen; Riitta Veijola; Tuula Simell; Mikael Knip; Olli Simell; Riitta Lahesmaa
Early suppression of immune response pathways characterizes children with prediabetes in genome-wide gene expression profiling.
Journal of autoimmunity 2010;35(1):70-6.
2010: Timo Hautala; Saara-Mari Mähönen; Tarja Sironen; Nina Hautala; Eija Pääkkö; Ari Karttunen; Pasi Salmela; Jorma Ilonen; Olli Vainio; Virpi Glumoff; Seppo Rytky; Alexander Plyusnin; Antti Vaheri; Olli Vapalahti; Heikki Kauma
Central nervous system-related symptoms and findings are common in acute Puumala hantavirus infection.
Annals of medicine 2010;42(5):344-51.
2010: Tapio Seiskari; Hanna Viskari; Anita Kondrashova; Anna-Maija Haapala; Jorma Ilonen; Mikael Knip; Heikki Hyöty
Co-occurrence of allergic sensitization and type 1 diabetes.
Annals of medicine 2010;42(5):352-9.
2010: Olga Kordonouri; Reinhard Hartmann; Klaus Badenhoop; Heinrich Kahles; Jorma Ilonen
PTPN22 1858T allele is associated with younger age at onset of type 1 diabetes and is not related to subsequent thyroid autoimmunity.
Human immunology 2010;71(7):731-2.
2010: Arno Hänninen; Merja Soilu-Hänninen; Christiane S Hampe; Angie Deptula; Kelly Geubtner; Jorma Ilonen; Mikael Knip; Helena Reijonen
Characterization of CD4+ T cells specific for glutamic acid decarboxylase (GAD65) and proinsulin in a patient with stiff-person syndrome but without type 1 diabetes.
Diabetes/metabolism research and reviews 2010;26(4):271-9.
2010: Satu Simell; Sanna Hoppu; Tuu Simell; Marja-Riitta Ståhlberg; Markku Viander; Taina Routi; Ville Simell; Riitta Veijola; Jorma Ilonen; Heikki Hyöty; Mikael Knip; Olli Simell
Age at development of type 1 diabetes- and celiac disease-associated antibodies and clinical disease in genetically susceptible children observed from birth.
Diabetes care 2010;33(4):774-9.
2010: Bright I Nwaru; Suvi Ahonen; Minna Kaila; Maijaliisa Erkkola; Anna-Maija Haapala; Carina Kronberg-Kippilä; Riitta Veijola; Jorma Ilonen; Olli Simell; Mikael Knip; Suvi M Virtanen
Maternal diet during pregnancy and allergic sensitization in the offspring by 5 yrs of age: a prospective cohort study.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2010;21(1 Pt 1):29-37.
2010: Emma M Savilahti; Jorma Ilonen; Minna Kiviniemi; Kristiina M Saarinen; Outi Vaarala; Erkki Savilahti
Human leukocyte antigen (DR1)-DQB1*0501 and (DR15)-DQB1*0602 haplotypes are associated with humoral responses to early food allergens in children.
International archives of allergy and immunology 2010;152(2):169-77.
2010: Bright I Nwaru; Maijaliisa Erkkola; Suvi Ahonen; Minna Kaila; Anna-Maija Haapala; Carina Kronberg-Kippilä; Raili Salmelin; Riitta Veijola; Jorma Ilonen; Olli Simell; Mikael Knip; Suvi M Virtanen
Age at the introduction of solid foods during the first year and allergic sensitization at age 5 years.
Pediatrics 2010;125(1):50-9.
2010: Suvi M Virtanen; Minna Kaila; Juha Pekkanen; Michael G Kenward; Ulla Uusitalo; Pirjo Pietinen; Carina Kronberg-Kippilä; Timo Hakulinen; Olli Simell; Jorma Ilonen; Riitta Veijola; Mikael Knip
Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis.
The British journal of nutrition 2010;103(2):266-73.
2009: Heli T A Siljander; Satu Simell; Anne Hekkala; Jyrki Lähde; Tuula Simell; Paula Vähäsalo; Riitta Veijola; Jorma Ilonen; Olli Simell; Mikael Knip
Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population.
Diabetes 2009;58(12):2835-42.
2009: Heli Siljander; Taina Härkönen; Robert Hermann; Satu Simell; Anne Hekkala; Riikka-Tiina Salonsaari; Tuula Simell; Olli Simell; Jorma Ilonen; Riitta Veijola; Mikael Knip
Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility.
Diabetes/metabolism research and reviews 2009;25(7):615-22.
2009: Johanna Lempainen; Outi Vaarala; Miia Mäkelä; Riitta Veijola; Olli Simell; Mikael Knip; Robert Hermann; Jorma Ilonen
Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.
Journal of autoimmunity 2009;33(2):155-64.
2009: Konstantinos Douroudis; Antti-Pekka Laine; Mirkka Heinonen; Robert Hermann; Kati Lipponen; Riitta Veijola; Olli Simell; Mikael Knip; Raivo Uibo; Jorma Ilonen; Kai E Kisand
Association of CTLA4 but not ICOS polymorphisms with type 1 diabetes in two populations with different disease rates.
Human immunology 2009;70(7):536-9.
2009: M Erkkola; M Kaila; B I Nwaru; Carina Kronberg-Kippilä; S Ahonen; J Nevalainen; Riitta Veijola; Juha Pekkanen; Jorma Ilonen; Olli Simell; Mikael Knip; Suvi M Virtanen
Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(6):875-82.
2009: Jorma Ilonen; Mirjana Kocova; Kati Lipponen; Elena Sukarova-Angelovska; Aleksandra Jovanovska; Mikael Knip
HLA-DR-DQ haplotypes and type 1 diabetes in Macedonia.
Human immunology 2009;70(6):461-3.
2009: Jorma Ilonen; Outi Vaarala; Hans K Akerblom; Mikael Knip
Environmental factors and primary prevention in type 1 diabetes.
Pediatric endocrinology, diabetes, and metabolism 2009;15(4):227-32.
2009: Minna Kiviniemi; Jorma Ilonen; Timo Lövgren
A homogeneous HLA-B*27 genotyping assay using dried reagent mixtures.
Disease markers 2009;27(2):85-91.
2009: Lena M Thorn; Carol Forsblom; Johan Wadén; Jenny Söderlund; Milla Rosengård-Bärlund; Markku Saraheimo; Outi Heikkilä; Kustaa Hietala; Kim Pettersson-Fernholm; Jorma Ilonen; Per-Henrik Groop
Effect of parental type 2 diabetes on offspring with type 1 diabetes.
Diabetes care 2009;32(1):63-8.
2008: Anna Lundberg; Lars Andersson Wikberg; Jorma Ilonen; Outi Vaarala; Malin Fagerås Böttcher
Lipopolysaccharide-induced immune responses in relation to the TLR4(Asp299Gly) gene polymorphism.
Clinical and vaccine immunology : CVI 2008;15(12):1878-83.
2008: Kirsti Näntö-Salonen; Antti Kupila; Satu Simell; Heli Siljander; Tiina Salonsaari; Anne Hekkala; Sari Korhonen; Risto Erkkola; J Sipilä; Lotta Haavisto; Marja Siltala; Juhani Tuominen; Jari Hakalax; Heikki Hyöty; Jorma Ilonen; Riitta Veijola; Tuula Simell; Mikael Knip; Olli Simell
Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.
Lancet 2008;372(9651):1746-55.
2008: M Oikarinen; Sisko Tauriainen; Teemu Honkanen; K Vuori; P Karhunen; C Vasama-Nolvi; Sami Oikarinen; C Verbeke; G E Blair; Immo Rantala; Jorma Ilonen; Olli Simell; Mikael Knip; Heikki Hyöty
Analysis of pancreas tissue in a child positive for islet cell antibodies.
Diabetologia 2008;51(10):1796-802.
2008: Kristiina Luopajärvi; Erkki Savilahti; Suvi M Virtanen; Jorma Ilonen; Mikael Knip; Hans K Akerblom; Outi Vaarala
Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood.
Pediatric diabetes 2008;9(5):434-41.
2008: J Walldén; Jorma Ilonen; M Roivainen; Johnny Ludvigsson; Outi Vaarala
Effect of HLA genotype or CTLA-4 polymorphism on cytokine response in healthy children.
Scandinavian journal of immunology 2008;68(3):345-50.
2008: Jane Marttila; Suvi Huttunen; Outi Vaarala; Kunimasa Suzuki; John Elliott; Ale Närvänen; Mikael Knip; Olli Simell; Jorma Ilonen
T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies.
Journal of autoimmunity 2008;31(2):142-8.
2008: Liisa Uusitalo; Mike Kenward; Suvi M Virtanen; Ulla Uusitalo; Jaakko Nevalainen; Sari Niinistö; Carina Kronberg-Kippilä; Marja-Leena Ovaskainen; Liisa Marjamäki; Olli Simell; Jorma Ilonen; Riitta Veijola; Mikael Knip
Intake of antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child.
The American journal of clinical nutrition 2008;88(2):458-64.
2008: Johanna Aarnisalo; Andras Treszl; Peter Svec; Jane Marttila; Viveka Oling; Olli Simell; Mikael Knip; Anna Körner; László Madácsy; Barna Vasarhelyi; Jorma Ilonen; Róbert Hermann
Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant.
Journal of autoimmunity 2008;31(1):13-21.
2008: Anna Mäkinen; Taina Härkönen; Jorma Ilonen; Mikael Knip
Characterization of the humoral immune response to islet antigen 2 in children with newly diagnosed type 1 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2008;159(1):19-26.
2008: Sisko Tauriainen; Sami Oikarinen; Kirsi Taimen; Jussi Laranne; Markku Sipilä; Maria Lönnrot; Jorma Ilonen; Olli Simell; Mikael Knip; Heikki Hyöty
Temporal relationship between human parechovirus 1 infection and otitis media in young children.
The Journal of infectious diseases 2008;198(1):35-40.
2008: Anna-Maija Vallittu; Juha-Pekka Erälinna; Jorma Ilonen; Aimo A Salmi; M Waris
MxA protein assay for optimal monitoring of IFN-beta bioactivity in the treatment of MS patients.
Acta neurologica Scandinavica 2008;118(1):12-7.
2008: Camilla Gullstrand; Jeanette Wahlberg; Jorma Ilonen; Outi Vaarala; Johnny Ludvigsson
Progression to type 1 diabetes and autoantibody positivity in relation to HLA-risk genotypes in children participating in the ABIS study.
Pediatric diabetes 2008;9(3 Pt 1):182-90.
2008: Liisa Uusitalo; Juha Nevalainen; S Niinistö; Georg Alfthan; Jouko Sundvall; T Korhonen; Mike Kenward; H Oja; Riitta Veijola; Olli Simell; Jorma Ilonen; Mikael Knip; Suvi M Virtanen
Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.
Diabetologia 2008;51(5):773-80.
2008: J Aarnisalo; Riitta Veijola; R Vainionpää; Olli Simell; Mikael Knip; Jorma Ilonen
Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes.
Diabetologia 2008;51(5):769-72.
2008: Ritva M Koskela; Tuomo J Karttunen; Seppo E Niemelä; Juhani Lehtola; Jorma Ilonen; Riitta Karttunen
Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis.
European journal of gastroenterology & hepatology 2008;20(4):276-82.
2008: Anita Kondrashova; Hanna Viskari; AM Haapala; Tapio Seiskari; Petri Kulmala; Jorma Ilonen; Mikael Knip; Heikki Hyöty
Serological evidence of thyroid autoimmunity among schoolchildren in two different socioeconomic environments.
The Journal of clinical endocrinology and metabolism 2008;93(3):729-34.
2008: Jenny Walldén; Jarno Honkanen; Jorma Ilonen; Johnny Ludvigsson; Outi Vaarala
No evidence for activation of T(H)1 or T(H)17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D.
Journal of inflammation research 2008;1():11-7.
2008: Anita Kondrashova; Kirsi Mustalahti; Katri Kaukinen; Hanna Viskari; Vera Volodicheva; AM Haapala; Jorma Ilonen; Mikael Knip; Markku Mäki; Heikki Hyöty
Lower economic status and inferior hygienic environment may protect against celiac disease.
Annals of medicine 2008;40(3):223-31.
2007: Zsofia Gombos; Róbert Hermann; Minna Kiviniemi; Sergey Nejentsev; Koit Reimand; V Fadeyev; Pärt Peterson; Raivo Uibo; Jorma Ilonen
Analysis of extended human leukocyte antigen haplotype association with Addison's disease in three populations.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(6):757-61.
2007: Saara-Mari Mähönen; Tarja Sironen; Olli Vapalahti; Eija Pääkkö; Nina Hautala; Jorma Ilonen; Virpi Glumoff; Olli Vainio; Heikki Kauma; Antti Vaheri; Alexander Plyusnin; Timo Hautala
Puumala virus RNA in cerebrospinal fluid in a patient with uncomplicated nephropathia epidemica.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;40(3):248-51.
2007: Matti Ankelo; V Kleimola; Satu Simell; Olli Simell; Mikael Knip; E Jokisalo; M Tarkia; Annette Westerlund; Q He; Markku Viander; Jorma Ilonen; Ari E Hinkkanen
Antibody responses to deamidated gliadin peptide show high specificity and parallel antibodies to tissue transglutaminase in developing coeliac disease.
Clinical and experimental immunology 2007;150(2):285-93.
2007: Minna Kiviniemi; Róbert Hermann; Jussi Nurmi; Anette-G Ziegler; Mikael Knip; Olli Simell; Riitta Veijola; Timo Lövgren; Jorma Ilonen
A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: an application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study.
Diabetes technology & therapeutics 2007;9(5):460-72.
2007: Satu Simell; Sanna Hoppu; Anne Hekkala; Tuula Simell; Marja-Riitta Ståhlberg; Markku Viander; Heta Yrjänäinen; Juhani Grönlund; Perttu Markula; Ville Simell; Mikael Knip; Jorma Ilonen; Heikki Hyöty; Olli Simell
Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study.
The American journal of gastroenterology 2007;102(9):2026-35.
2007: Viveka Oling; Jane Marttila; Mikael Knip; Olli Simell; Jorma Ilonen
Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies.
Annals of the New York Academy of Sciences 2007;1107():363-72.
2007: Kristiina Luopajärvi; Susanne Skarsvik; Jorma Ilonen; Hans K Akerblom; Outi Vaarala
Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes.
Immunology 2007;121(2):189-96.
2007: Annette Westerlund; Matti Ankelo; Satu Simell; Jorma Ilonen; Mikael Knip; Olli Simell; Ari E Hinkkanen
Affinity maturation of immunoglobulin A anti-tissue transglutaminase autoantibodies during development of coeliac disease.
Clinical and experimental immunology 2007;148(2):230-40.
2007: Sisko Tauriainen; Mika Martiskainen; Sami Oikarinen; Maria Lönnrot; Hanna Viskari; Jorma Ilonen; Olli Simell; Mikael Knip; Heikki Hyöty
Human parechovirus 1 infections in young children--no association with type 1 diabetes.
Journal of medical virology 2007;79(4):457-62.
2007: Matti Ankelo; Annette Westerlund; Kaj Blomberg; Mikael Knip; Jorma Ilonen; Ari E Hinkkanen
Time-resolved immunofluorometric dual-label assay for simultaneous detection of autoantibodies to GAD65 and IA-2 in children with type 1 diabetes.
Clinical chemistry 2007;53(3):472-9.
2007: Antti-Pekka Laine; Hanna Holmberg; Anita Nilsson; Eva Ortqvist; Minna Kiviniemi; Outi Vaarala; Hans K Akerblom; Olli Simell; Mikael Knip; Johnny Ludvigsson; Sten-A Ivarsson; Karin Larsson; Ake Lernmark; Jorma Ilonen
Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations.
Disease markers 2007;23(3):139-45.
2007: Anita Kondrashova; Hanna Viskari; Petri Kulmala; Anatolij Romanov; Jorma Ilonen; Heikki Hyöty; Mikael Knip
Signs of beta-cell autoimmunity in nondiabetic schoolchildren: a comparison between Russian Karelia with a low incidence of type 1 diabetes and Finland with a high incidence rate.
Diabetes care 2007;30(1):95-100.
2006: Minna M Koskenvuo; Markus Halminen; Miia Blomqvist; Raija Vainionpää; Jorma Ilonen; Ilkka Julkunen; Toivo T Salmi; Mika J Mäkelä
Expression of MxA protein in blood lymphocytes of children receiving anticancer chemotherapy.
Pediatric hematology and oncology 2006;23(8):649-60.
2006: S Laivoranta-Nyman; Timo Möttönen; Pekka Hannonen; Markku Korpela; Hannu Kautiainen; Marjatta Leirisalo-Repo; Heikki Julkunen; Reijo Luukkainen; Markku Hakala; Kaisa Vuori; A P Laine; Auli Toivanen; Jorma Ilonen
Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis.
Clinical and experimental rheumatology 2006;24(6):636-42.
2006: Paula Simonen; Tapio Korhonen; Tuula Simell; Päivi Keskinen; Maarit Kärkkäinen; Mikael Knip; Jorma Ilonen; Olli Simell
Parental reactions to information about increased genetic risk of type 1 diabetes mellitus in infants.
Archives of pediatrics & adolescent medicine 2006;160(11):1131-6.
2006: Minna Tiittanen; Johanna Paronen; Erkki Savilahti; Suvi M Virtanen; Jorma Ilonen; Mikael Knip; Hans K Akerblom; Outi Vaarala
Dietary insulin as an immunogen and tolerogen.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2006;17(7):538-43.
2006: Maria Karlsson Faresjö; Outi Vaarala; Sophie Thuswaldner; Jorma Ilonen; Ari E Hinkkanen; Johnny Ludvigsson
Diminished IFN-gamma response to diabetes-associated autoantigens in children at diagnosis and during follow up of type 1 diabetes.
Diabetes/metabolism research and reviews 2006;22(6):462-70.
2006: Martin Ljungberg; Riita Korpela; Jorma Ilonen; Johnny Ludvigsson; Outi Vaarala
Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes--the PRODIA study.
Annals of the New York Academy of Sciences 2006;1079():360-4.
2006: Pauli Vuorinen; Maris Rulli; Ari Kuusisto; Satu Simell; Tuula Simell; Tero Vahlberg; Jorma Ilonen; Heikki Hyöty; Mikael Knip; Olli Simell
Time-resolved fluorescence imaging of islet cell autoantibodies.
Annals of the New York Academy of Sciences 2006;1079():226-8.
2006: Matti S Ronkainen; Sanna Hoppu; Sari Korhonen; Satu Simell; Riitta Veijola; Jorma Ilonen; Olli Simell; Mikael Knip
Early epitope- and isotype-specific humoral immune responses to GAD65 in young children with genetic susceptibility to type 1 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(4):633-42.
2006: Zsofia Gombos; Joanna Wachowicz; Riitta Veijola; Hans K Akerblom; Olli Simell; Mikael Knip; Jorma Ilonen; Róbert Hermann
Human leukocyte antigen non-class II determinants for type 1 diabetes in the Finnish population.
Human immunology 2006;67(9):714-21.
2006: M Mäkelä; Viveka Oling; Jane Marttila; Matti Waris; Mikael Knip; Olli Simell; Jorma Ilonen
Rotavirus-specific T cell responses and cytokine mRNA expression in children with diabetes-associated autoantibodies and type 1 diabetes.
Clinical and experimental immunology 2006;145(2):261-70.
2006: Jonas Ludvigsson; Maike Eylert; Jorma Ilonen; Johnny Ludvigson; Outi Vaarala
Effect of HLA DQ2, dietary exposure and coeliac disease on the development of antibody response to gliadin in children.
Scandinavian journal of gastroenterology 2006;41(8):919-28.
2006: Miia Mäkelä; Outi Vaarala; Róbert Hermann; Kimmo Salminen; Tero Vahlberg; Riitta Veijola; Heikki Hyöty; Mikael Knip; Olli Simell; Jorma Ilonen
Enteral virus infections in early childhood and an enhanced type 1 diabetes-associated antibody response to dietary insulin.
Journal of autoimmunity 2006;27(1):54-61.
2006: C-O Jonson; M Hedman; M G E Karlsson Faresjö; R Casas; Jorma Ilonen; Johnny Ludvigsson; Outi Vaarala
The association of CTLA-4 and HLA class II autoimmune risk genotype with regulatory T cell marker expression in 5-year-old children.
Clinical and experimental immunology 2006;145(1):48-55.
2006: Suvi M Virtanen; Mike Kenward; Maijaliisa Erkkola; Susanna Kautiainen; Carina Kronberg-Kippilä; T Hakulinen; Suvi Ahonen; Liisa Uusitalo; S Niinistö; Riitta Veijola; Olli Simell; Jorma Ilonen; Mikael Knip
Age at introduction of new foods and advanced beta cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes.
Diabetologia 2006;49(7):1512-21.
2006: Róbert Hermann; K Lipponen; Minna Kiviniemi; T Kakko; Riitta Veijola; Olli Simell; Mikael Knip; Jorma Ilonen
Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes.
Diabetologia 2006;49(6):1198-208.
2006: Hanna Holmberg; Outi Vaarala; Vaiva Sadauskaite-Kuehne; Jorma Ilonen; Zilvinas Padaiga; Johnny Ludvigsson
Higher prevalence of autoantibodies to insulin and GAD65 in Swedish compared to Lithuanian children with type 1 diabetes.
Diabetes research and clinical practice 2006;72(3):308-14.
2006: Anna Toivonen; Teija Kimpimäki; Antti Kupila; Sari Korhonen; Heikki Hyöty; Suvi M Virtanen; Jorma Ilonen; Olli Simell; Mikael Knip
Soluble adhesion molecules in young children with signs of beta-cell autoimmunity--prospective follow-up from birth.
Diabetes/metabolism research and reviews 2006;22(3):176-83.
2006: Susanne Skarsvik; Julia Puranen; Jarno Honkanen; Merja Roivainen; Jorma Ilonen; Hanna Holmberg; Johnny Ludvigsson; Outi Vaarala
Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes.
Diabetes 2006;55(4):996-1003.
2006: Sanna Hoppu; Taina Härkönen; Matti S Ronkainen; Satu Simell; Anne Hekkala; Anna Toivonen; Jorma Ilonen; Olli Simell; Mikael Knip
IA-2 antibody isotypes and epitope specificity during the prediabetic process in children with HLA-conferred susceptibility to type I diabetes.
Clinical and experimental immunology 2006;144(1):59-66.
2006: Antti-Pekka Laine; Hannu Turpeinen; Riitta Veijola; Róbert Hermann; Olli Simell; Mikael Knip; Jorma Ilonen
Evidence for linkage to and association with type 1 diabetes at the 3q21 region in the Finnish population.
Genes and immunity 2006;7(1):69-72.
2006: Marika Kukko; Anna Toivonen; Antti Kupila; Sari Korhonen; Päivi Keskinen; Riitta Veijola; Suvi M Virtanen; Jorma Ilonen; Olli Simell; Mikael Knip
Familial clustering of beta-cell autoimmunity in initially non-diabetic children.
Diabetes/metabolism research and reviews 2006;22(1):53-8.
2005: Laura Paajanen; Riitta Korpela; Tuula Tuure; Jarno Honkanen; Irma Järvelä; Jorma Ilonen; Mikael Knip; Outi Vaarala; Jorma Kokkonen
Cow milk is not responsible for most gastrointestinal immune-like syndromes--evidence from a population-based study.
The American journal of clinical nutrition 2005;82(6):1327-35.
2005: Alexander Lukashev; Vasilii A Lashkevich; Olga E Ivanova; Galina A Koroleva; Ari E Hinkkanen; Jorma Ilonen
Recombination in circulating Human enterovirus B: independent evolution of structural and non-structural genome regions.
The Journal of general virology 2005;86(Pt 12):3281-90.
2005: Viveka Oling; Jane Marttila; Jorma Ilonen; William W Kwok; Gerald Nepom; Mikael Knip; Olli Simell; Helena Reijonen
GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.
Journal of autoimmunity 2005;25(3):235-43.
2005: Minna Kiviniemi; Jussi Nurmi; Timo Lövgren; Jorma Ilonen
Locked nucleic acid (LNA) probes in high-throughput genetic analysis: application to an assay for type 1 diabetes-related HLA-DQB1 alleles.
Clinical biochemistry 2005;38(11):1015-22.
2005: Satu Simell; Antti Kupila; Sanna Hoppu; Anne Hekkala; Tuula Simell; Marja-Riitta Ståhlberg; Markku Viander; Timo Hurme; Mikael Knip; Jorma Ilonen; Heikki Hyöty; Olli Simell
Natural history of transglutaminase autoantibodies and mucosal changes in children carrying HLA-conferred celiac disease susceptibility.
Scandinavian journal of gastroenterology 2005;40(10):1182-91.
2005: Róbert Hermann; Jussi Mantere; Kati Lipponen; Riitta Veijola; Gyula Soltesz; Timo Otonkoski; Olli Simell; Mikael Knip; Jorma Ilonen
Lack of association of PAX4 gene with type 1 diabetes in the Finnish and Hungarian populations.
Diabetes 2005;54(9):2816-9.
2005: Róbert Hermann; Antti-Pekka Laine; Riitta Veijola; Tero Vahlberg; Satu Simell; J Lähde; Olli Simell; Mikael Knip; Jorma Ilonen
The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity.
Diabetologia 2005;48(9):1766-75.
2005: Maijaliisa Erkkola; Carina Kronberg-Kippilä; Erkki Savilahti; Mike Kenward; Marja Salonen; Jorma Ilonen; Mikael Knip; Hans K Akerblom; Suvi M Virtanen
Maternal consumption of dairy products during pregnancy and lactation, and the development of cow's milk antibodies in the offspring.
Acta paediatrica (Oslo, Norway : 1992) 2005;94(6):696-704.
2005: Marika Kukko; Teija Kimpimäki; Sari Korhonen; Antti Kupila; Satu Simell; Riitta Veijola; Tuula Simell; Jorma Ilonen; Olli Simell; Mikael Knip
Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population.
The Journal of clinical endocrinology and metabolism 2005;90(5):2712-7.
2005: Hans K Akerblom; Suvi M Virtanen; Jorma Ilonen; Erkki Savilahti; Outi Vaarala; Antti Reunanen; Kari Teramo; Anu-Maaria Hämäläinen; Johanna Paronen; M-A Riikjärv; A Ormisson; J Ludvigsson; H-M Dosch; T Hakulinen; Mikael Knip
Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study.
Diabetologia 2005;48(5):829-37.
2005: Annette Westerlund; Matti Ankelo; Jorma Ilonen; Mikael Knip; Olli Simell; Ari E Hinkkanen
Absence of avidity maturation of autoantibodies to the protein tyrosine phosphatase-like IA-2 molecule and glutamic acid decarboxylase (GAD65) during progression to type 1 diabetes.
Journal of autoimmunity 2005;24(2):153-67.
2005: Omar M Hauache; André F Reis; Carolina S V Oliveira; José Gilberto H Vieira; Minna Sjöroos; Jorma Ilonen
Estimation of diabetes risk in Brazilian population by typing for polymorphisms in HLA-DR-DQ, INS and CTLA-4 genes.
Disease markers 2005;21(3):139-45.
2005: Anita Kondrashova; Antti Reunanen; Anatolij Romanov; Aino Karvonen; Hanna Viskari; Timo Vesikari; Jorma Ilonen; Mikael Knip; Heikki Hyöty
A six-fold gradient in the incidence of type 1 diabetes at the eastern border of Finland.
Annals of medicine 2005;37(1):67-72.
2004: S Laivoranta-Nyman; Timo Möttönen; Róbert Hermann; J Tuokko; Reijo Luukkainen; Markku Hakala; Pekka Hannonen; Markku Korpela; U Yli-Kerttula; Auli Toivanen; Jorma Ilonen
HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(11):1406-12.
2004: Róbert Hermann; Christos S Bartsocas; Gy Soltész; Andriani Vazeou; Peristera Paschou; Evangelos Bozas; Ariadne Malamitsi-Puchner; Olli Simell; Mikael Knip; Jorma Ilonen
Genetic screening for individuals at high risk for type 1 diabetes in the general population using HLA Class II alleles as disease markers. A comparison between three European populations with variable rates of disease incidence.
Diabetes/metabolism research and reviews 2004;20(4):322-9.
2004: M Mäkelä; Jane Marttila; Olli Simell; Jorma Ilonen
Rotavirus-specific T-cell responses in young prospectively followed-up children.
Clinical and experimental immunology 2004;137(1):173-8.
2004: Antti-Pekka Laine; Sergey Nejentsev; Riitta Veijola; Eija Korpinen; Minna Sjöroos; Olli Simell; Mikael Knip; Hans K Akerblom; Jorma Ilonen
A linkage study of 12 IDDM susceptibility loci in the Finnish population.
Diabetes/metabolism research and reviews 2004;20(2):144-9.
2004: Marika Kukko; Suvi M Virtanen; Anna Toivonen; Satu Simell; Sari Korhonen; Jorma Ilonen; Olli Simel; Mikael Knip
Geographical variation in risk HLA-DQB1 genotypes for type 1 diabetes and signs of beta-cell autoimmunity in a high-incidence country.
Diabetes care 2004;27(3):676-81.
2004: Jane Marttila; Heikki Hyöty; Kirsti Näntö-Salonen; Olli Simell; Jorma Ilonen
Epitopes recognized by CBV4 responding T cells: effect of type 1 diabetes and associated HLA-DR-DQ haplotypes.
Virology 2004;319(1):27-35.
2004: Kimmo Salminen; T Vuorinen; Sami Oikarinen; M Helminen; Satu Simell; Mikael Knip; Jorma Ilonen; Olli Simell; Heikki Hyöty
Isolation of enterovirus strains from children with preclinical Type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(2):156-64.
2004: Alexander Lukashev; Vasilii A Lashkevich; Galina A Koroleva; Jorma Ilonen; Ari E Hinkkanen
Recombination in uveitis-causing enterovirus strains.
The Journal of general virology 2004;85(Pt 2):463-70.
2004: Sanna Hoppu; Matti S Ronkainen; Teija Kimpimäki; Satu Simell; Sari Korhonen; Jorma Ilonen; Olli Simell; Mikael Knip
Insulin autoantibody isotypes during the prediabetic process in young children with increased genetic risk of type 1 diabetes.
Pediatric research 2004;55(2):236-42.
2004: Jorma Ilonen
[Genetic background of diabetes mellitus, type I].
Duodecim; lääketieteellinen aikakauskirja 2004;120(9):1139-45.
2004: Anna Toivonen; Petri Kulmala; Jukka Rahko; Jorma Ilonen; Mikael Knip
Soluble adhesion molecules in Finnish schoolchildren with signs of preclinical type 1 diabetes.
Diabetes/metabolism research and reviews 2004;20(1):48-54.
2004: Antti-Pekka Laine; Róbert Hermann; Mikael Knip; Olli Simell; Hans K Akerblom; Jorma Ilonen
The human leukocyte antigen genotype has a modest effect on the insulin gene polymorphism-associated susceptibility to type 1 diabetes in the Finnish population.
Tissue antigens 2004;63(1):72-4.
2003: Zsofia Gombos; Róbert Hermann; Riitta Veijola; Mikael Knip; Olli Simell; Pasi Pöllänen; Jorma Ilonen
Androgen receptor gene exon 1 CAG repeat polymorphism in Finnish patients with childhood-onset type 1 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2003;149(6):597-600.
2003: Hannu Turpeinen; Róbert Hermann; Satu Vaara; Antti-Pekka Laine; Olli Simell; Mikael Knip; Riitta Veijola; Jorma Ilonen
Vitamin D receptor polymorphisms: no association with type 1 diabetes in the Finnish population.
European journal of endocrinology / European Federation of Endocrine Societies 2003;149(6):591-6.
2003: Minna Kiviniemi; Jussi Nurmi; Hannu Turpeinen; Timo Lövgren; Jorma Ilonen
A homogeneous high-throughput genotyping method based on competitive hybridization.
Clinical biochemistry 2003;36(8):633-40.
2003: Mikko Laaksonen; Aslaug Jonasdottir; Ragnheidur Fossdal; Juhani Ruutiainen; Stephen Sawcer; Alastair Compston; Kjartan Benediktsson; Theodora Thorlacius; Jeffrey R Gulcher; Jorma Ilonen
A whole genome association study in Finnish multiple sclerosis patients with 3669 markers.
Journal of neuroimmunology 2003;143(1-2):70-3.
2003: Alexander Lukashev; Vasilii A Lashkevich; Olga E Ivanova; Galina A Koroleva; Ari E Hinkkanen; Jorma Ilonen
Recombination in circulating enteroviruses.
Journal of virology 2003;77(19):10423-31.
2003: Mia Westerholm-Ormio; Outi Vaarala; Päivi Pihkala; Jorma Ilonen; Erkki Savilahti
Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes.
Diabetes 2003;52(9):2287-95.
2003: Hanna Viskari; J Paronen; Päivi Keskinen; Satu Simell; B Zawilinska; I Zgorniak-Nowosielska; Sari Korhonen; Jorma Ilonen; Olli Simell; AM Haapala; Mikael Knip; Heikki Hyöty
Humoral beta-cell autoimmunity is rare in patients with the congenital rubella syndrome.
Clinical and experimental immunology 2003;133(3):378-83.
2003: Hannu Turpeinen; Antti-Pekka Laine; Róbert Hermann; Olli Simell; Riitta Veijola; Mikael Knip; Jorma Ilonen
A linkage analysis of the CTLA4 gene region in Finnish patients with type 1 diabetes.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003;30(4):289-93.
2003: Róbert Hermann; Hannu Turpeinen; Antti-Pekka Laine; Riitta Veijola; Mikael Knip; Olli Simell; I Sipilä; Hans K Akerblom; Jorma Ilonen
HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families.
Tissue antigens 2003;62(2):162-9.
2003: Markku Mäki; Kirsi Mustalahti; Jorma Kokkonen; Petri Kulmala; Mila Haapalahti; Tuomo J Karttunen; Jorma Ilonen; Kaija Laurila; Ingrid Dahlbom; Tony Hansson; Peter Höpfl; Mikael Knip
Prevalence of Celiac disease among children in Finland.
The New England journal of medicine 2003;348(25):2517-24.
2003: Annu Alho; Jane Marttila; Jorma Ilonen; Timo Hyypiä
Diagnostic potential of parechovirus capsid proteins.
Journal of clinical microbiology 2003;41(6):2294-9.
2003: Samy Mrena; Kaisa Savola; Petri Kulmala; Helena Reijonen; Jorma Ilonen; Hans K Akerblom; Mikael Knip
Genetic modification of risk assessment based on staging of preclinical type 1 diabetes in siblings of affected children.
The Journal of clinical endocrinology and metabolism 2003;88(6):2682-9.
2003: Annette Westerlund-Karlsson; Katriina Suonpää; Matti Ankelo; Jorma Ilonen; Mikael Knip; Ari E Hinkkanen
Detection of autoantibodies to protein tyrosine phosphatase-like protein IA-2 with a novel time-resolved fluorimetric assay.
Clinical chemistry 2003;49(6 Pt 1):916-23.
2003: Matti Ankelo; Annette Westerlund-Karlsson; Jorma Ilonen; Mikael Knip; Kaisa Savola; Pasi Kankaanpää; Liisa Meriö; Harri Siitari; Ari E Hinkkanen
Time-resolved fluorometric assay for detection of autoantibodies to glutamic acid decarboxylase (GAD65).
Clinical chemistry 2003;49(6 Pt 1):908-15.
2003: Karita Sadeharju; Anu-Maaria Hämäläinen; Mikael Knip; Maria Lönnrot; Pentti Koskela; Suvi M Virtanen; Jorma Ilonen; Hans K Akerblom; Heikki Hyöty
Enterovirus infections as a risk factor for type I diabetes: virus analyses in a dietary intervention trial.
Clinical and experimental immunology 2003;132(2):271-7.
2003: Ase Karttunen; Tuija Pöyry; Outi Vaarala; Jorma Ilonen; Tapani Hovi; Merja Roivainen; Timo Hyypiä
Variation in enterovirus receptor genes.
Journal of medical virology 2003;70(1):99-108.
2003: Róbert Hermann; Riitta Veijola; I Sipilä; Mikael Knip; Hans K Akerblom; Olli Simell; Jorma Ilonen
-to: Pani MA, Van Autreve J, Van Der Auwera BJ, Gorus FK, Badenhoop K (2002) Non-transmitted maternal HLA DQ2 or DQ8 alleles and risk of Type I diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 45:1340-1343.
Diabetologia 2003;46(4):588-9; author reply 591-2.
2003: Róbert Hermann; Mikael Knip; Riitta Veijola; Olli Simell; Antti-Pekka Laine; Hans K Akerblom; Per-Henrik Groop; Carol Forsblom; Kim Pettersson-Fernholm; Jorma Ilonen
Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure?
Diabetologia 2003;46(3):420-5.
2003: Alexander Lukashev; Vasilii A Lashkevich; Galina A Koroleva; Jorma Ilonen; Galina Karganova; VI Reznik; Ari E Hinkkanen
Molecular epidemiology of enteroviruses causing uveitis and multisystem hemorrhagic disease of infants.
Virology 2003;307(1):45-53.
2003: Hannele Pihlaja; Terhi Rantamäki; Juhani Wikström; Marja-Liisa Sumelahti; M Laaksonen; Jorma Ilonen; Juhani Ruutiainen; T Pirttilä; Irina Elovaara; Mauri Reunanen; Satu Kuokkanen; Leena Peltonen; Keijo Koivisto; Pentti J Tienari
Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland.
Genes and immunity 2003;4(2):138-46.
2003: Sergey Nejentsev; Mikko Laaksonen; Pentti J Tienari; Oscar Fernandez; Heather Cordell; Juhani Ruutiainen; Juhani Wikström; Tomi Pastinen; Satu Kuokkanen; Jan Hillert; Jorma Ilonen
Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis.
Human immunology 2003;64(3):345-9.
2003: Johanna Aarnisalo; Jorma Ilonen; Raija Vainionpää; Iina Volanen; Tuuli Kaitosaari; Olli Simell
Development of antibodies against cytomegalovirus, varicella-zoster virus and herpes simplex virus in Finland during the first eight years of life: a prospective study.
Scandinavian journal of infectious diseases 2003;35(10):750-3.
2003: Iina Volanen; Raija Vainionpää; Jorma Ilonen; Perttu Markula; Katariina Kallio; Tuuli Kaitosaari; Hans Helenius; Olli Simell
A prospective study of Chlamydia pneumoniae antibodies in children between 7 months and 8 years of age.
Scandinavian journal of infectious diseases 2003;35(8):471-7.
2003: Marika Kukko; Teija Kimpimäki; Antti Kupila; Sari Korhonen; Petri Kulmala; Kaisa Savola; Tuula Simell; Päivi Keskinen; Jorma Ilonen; Olli Simell; Mikael Knip
Signs of beta-cell autoimmunity and HLA-defined diabetes susceptibility in the Finnish population: the sib cohort from the Type 1 Diabetes Prediction and Prevention Study.
Diabetologia 2003;46(1):65-70.
2003: Jarmo Hahl; Tuula Simell; Antti Kupila; Päivi Keskinen; Mikael Knip; Jorma Ilonen; Olli Simell
A simulation model for estimating direct costs of type 1 diabetes prevention.
PharmacoEconomics 2003;21(5):295-303.
2003: Kimmo Salminen; Karita Sadeharju; Maria Lönnrot; Paula Vähäsalo; Antti Kupila; Sari Korhonen; Jorma Ilonen; Olli Simell; Mikael Knip; Heikki Hyöty
Enterovirus infections are associated with the induction of beta-cell autoimmunity in a prospective birth cohort study.
Journal of medical virology 2003;69(1):91-8.
2002: Päivi Keskinen; Sari Korhonen; Antti Kupila; Riitta Veijola; Satu Erkkilä; H Savolainen; Paula Arvilommi; Tuula Simell; Jorma Ilonen; Mikael Knip; Olli Simell
First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.
Diabetologia 2002;45(12):1639-48.
2002: Teija Kimpimäki; Petri Kulmala; Kaisa Savola; Antti Kupila; Sari Korhonen; Tuula Simell; Jorma Ilonen; Olli Simell; Mikael Knip
Natural history of beta-cell autoimmunity in young children with increased genetic susceptibility to type 1 diabetes recruited from the general population.
The Journal of clinical endocrinology and metabolism 2002;87(10):4572-9.
2002: Mikael Kuitunen; Tero Saukkonen; Jorma Ilonen; Hans K Akerblom; Erkki Savilahti
Intestinal permeability to mannitol and lactulose in children with type 1 diabetes with the HLA-DQB1*02 allele.
Autoimmunity 2002;35(5):365-8.
2002: Hannu Turpeinen; Antti-Pekka Laine; Sergey Nejentsev; Minna Sjöroos; Jorma Ilonen; Olli Simell; Riitta Veijola; Mikael Knip; Hans K Akerblom; M Knip
CD86 gene polymorphisms: no association with Type I diabetes among Finnish subjects.
Diabetologia 2002;45(7):1041-2.
2002: Anna-Maija Vallittu; Markus Halminen; Jutta Peltoniemi; Jorma Ilonen; Ilkka Julkunen; Aimo A Salmi; Juha-Pekka Erälinna
Neutralizing antibodies reduce MxA protein induction in interferon-beta-1a-treated MS patients.
Neurology 2002;58(12):1786-90.
2002: M Blomqvist; S Juhela; S Erkkila; Sari Korhonen; Tuula Simell; Antti Kupila; Outi Vaarala; Olli Simell; Mikael Knip; Jorma Ilonen
Rotavirus infections and development of diabetes-associated autoantibodies during the first 2 years of life.
Clinical and experimental immunology 2002;128(3):511-5.
2002: Mikael Knip; Marika Kukko; Petri Kulmala; Riitta Veijola; Olli Simell; Hans K Akerblom; Jorma Ilonen
Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes.
American journal of medical genetics 2002;115(1):48-54.
2002: Jorma Ilonen; Minna Sjöroos; Mikael Knip; Riitta Veijola; Olli Simell; Hans K Akerblom; Peristera Paschou; Evangelos Bozas; Beatrice Havarani; Ariadne Malamitsi-Puchner; Joanna Thymelli; Andriani Vazeou; Christos S Bartsocas
Estimation of genetic risk for type 1 diabetes.
American journal of medical genetics 2002;115(1):30-6.
2002: Hans K Akerblom; Outi Vaarala; Heikki Hyöty; Jorma Ilonen; Mikael Knip
Environmental factors in the etiology of type 1 diabetes.
American journal of medical genetics 2002;115(1):18-29.
2002: Karoliina Reunanen; Saara Finnilä; Mikko Laaksonen; Marja-Liisa Sumelahti; Juhani Wikström; Tomi Pastinen; Satu Kuokkanen; Janna Saarela; P Uimari; Juhani Ruutiainen; Jorma Ilonen; Leena Peltonen; Pentti J Tienari
Chromosome 19q13 and multiple sclerosis susceptibility in Finland: a linkage and two-stage association study.
Journal of neuroimmunology 2002;126(1-2):134-42.
2002: Outi Vaarala; P Klemetti; S Juhela; Olli Simell; Heikki Hyöty; Jorma Ilonen
Effect of coincident enterovirus infection and cows' milk exposure on immunisation to insulin in early infancy.
Diabetologia 2002;45(4):531-4.
2002: Timo Möttönen; Pekka Hannonen; Markku Korpela; Martti Nissilä; Hannu Kautiainen; Jorma Ilonen; Leena Laasonen; Oili Kaipiainen-Seppänen; Per Franzen; Tapani Helve; Juhani Koski; Marianne Gripenberg-Gahmberg; Riitta Myllykangas-Luosujärvi; Marjatta Leirisalo-Repo
Delay to institution of therapy and induction of remission using single-drug or combination-disease-modifying antirheumatic drug therapy in early rheumatoid arthritis.
Arthritis and rheumatism 2002;46(4):894-8.
2002: Antti Kupila; Päivi Keskinen; Tuula Simell; Satu Erkkilä; Paula Arvilommi; Sari Korhonen; Teija Kimpimäki; Minna Sjöroos; Matti S Ronkainen; Jorma Ilonen; Mikael Knip; Olli Simell
Genetic risk determines the emergence of diabetes-associated autoantibodies in young children.
Diabetes 2002;51(3):646-51.
2002: Jane Marttila; Heikki Hyöty; Pekka Vilja; Taina Härkönen; Annu Alho; Merja Roivainen; Timo Hyypiä; Jorma Ilonen
T cell epitopes in coxsackievirus B4 structural proteins concentrate in regions conserved between enteroviruses.
Virology 2002;293(2):217-24.
2002: Kaisa Nieminen; Markus Halminen; Matti Waris; Mika Mäkelä; Johannes Savolainen; Minna Sjöroos; Jorma Ilonen
Time-resolved fluorometric detection of cytokine mRNAs amplified by RT-PCR.
Methods in molecular biology (Clifton, N.J.) 2002;193():117-27.
2002: Anu-Maaria Hämäläinen; Jorma Ilonen; Olli Simell; Kaisa Savola; Petri Kulmala; Antti Kupila; Tuula Simell; Risto Erkkola; Pentti Koskela; Mikael Knip
Prevalence and fate of type 1 diabetes-associated autoantibodies in cord blood samples from newborn infants of non-diabetic mothers.
Diabetes/metabolism research and reviews 2002;18(1):57-63.
2002: Mikko Laaksonen; Tomi Pastinen; Minna Sjöroos; Satu Kuokkanen; Juhani Ruutiainen; Marja-Liisa Sumelahti; Helena Reijonen; Reijo Salonen; Juhani Wikström; Martin Panelius; Jukka Partanen; Pentti J Tienari; Jorma Ilonen
HLA class II associated risk and protection against multiple sclerosis-a Finnish family study.
Journal of neuroimmunology 2002;122(1-2):140-5.
2001: Jussi Nurmi; Minna Kiviniemi; M Kujanpää; Minna Sjöroos; Jorma Ilonen; Timo Lövgren
High-throughput genetic analysis using time-resolved fluorometry and closed-tube detection.
Analytical biochemistry 2001;299(2):211-7.
2001: L Heino; Maria Lönnrot; Mikael Knip; Antti Kupila; Satu Erkkilä; Anna Toivonen; Paula Vähäsalo; Jorma Ilonen; Olli Simell; Heikki Hyöty
No evidence of abnormal regulation of antibody response to coxsackievirus B4 antigen in prediabetic children.
Clinical and experimental immunology 2001;126(3):432-6.
2001: Teija Kimpimäki; Antti Kupila; Anu-Maaria Hämäläinen; Marika Kukko; Petri Kulmala; Kaisa Savola; Tuula Simell; Päivi Keskinen; Jorma Ilonen; Olli Simell; Mikael Knip
The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.
The Journal of clinical endocrinology and metabolism 2001;86(10):4782-8.
2001: Tero Saukkonen; Jorma Ilonen; Hans K Akerblom; Erkki Savilahti
Prevalence of coeliac disease in siblings of patients with Type I diabetes is related to the prevalence of DQB1*02 allele.
Diabetologia 2001;44(8):1051-3.
2001: Karita Sadeharju; Maria Lönnrot; Teija Kimpimäki; Kaisa Savola; Satu Erkkilä; T Kalliokoski; P Savolainen; Pentti Koskela; Jorma Ilonen; Olli Simell; Mikael Knip; Heikki Hyöty
Enterovirus antibody levels during the first two years of life in prediabetic autoantibody-positive children.
Diabetologia 2001;44(7):818-23.
2001: Jane Marttila; S Juhela; Outi Vaarala; Heikki Hyöty; Merja Roivainen; Ari E Hinkkanen; Pekka Vilja; Olli Simell; Jorma Ilonen
Responses of coxsackievirus B4-specific T-cell lines to 2C protein-characterization of epitopes with special reference to the GAD65 homology region.
Virology 2001;284(1):131-41.
2001: M Halminen; O Simell; Mikael Knip; Jorma Ilonen
Cytokine expression in unstimulated PBMC of children with type 1 diabetes and subjects positive for diabetes-associated autoantibodies.
Scandinavian journal of immunology 2001;53(5):510-3.
2001: S Laivoranta-Nyman; Reijo Luukkainen; Markku Hakala; Pekka Hannonen; Timo Möttönen; U Yli-Kerttula; Jorma Ilonen; Auli Toivanen
Differences between female and male patients with familial rheumatoid arthritis.
Annals of the rheumatic diseases 2001;60(4):413-5.
2001: Antti Kupila; P Muona; Tuula Simell; Paula Arvilommi; H Savolainen; Anu-Maaria Hämäläinen; Sari Korhonen; Teija Kimpimäki; Minna Sjöroos; Jorma Ilonen; Mikael Knip; Olli Simell
Feasibility of genetic and immunological prediction of type I diabetes in a population-based birth cohort.
Diabetologia 2001;44(3):290-7.
2001: Minna Sjöroos; Jorma Ilonen; Timo Lövgren
Solid-phase PCR with hybridization and time-resolved fluorometry for detection of HLA-B27.
Clinical chemistry 2001;47(3):498-504.
2001: J Tuokko; Sergey Nejentsev; Reijo Luukkainen; Auli Toivanen; Jorma Ilonen
HLA haplotype analysis in Finnish patients with rheumatoid arthritis.
Arthritis and rheumatism 2001;44(2):315-22.
2001: Jane Marttila; Ari E Hinkkanen; T Ziegler; Raija Vainionpää; Aimo A Salmi; Jorma Ilonen
Cell membrane-associated measles virus components inhibit antigen processing.
Virology 2001;279(2):422-8.
2001: Markus Halminen; S Juhela; Outi Vaarala; Olli Simell; Jorma Ilonen
Induction of interferon-gamma and IL-4 production by mitogen and specific antigens in peripheral blood lymphocytes of Type 1 diabetes patients.
Autoimmunity 2001;34(1):1-8.
2001: Teija Kimpimäki; Maijaliisa Erkkola; Sari Korhonen; Antti Kupila; Suvi M Virtanen; Jorma Ilonen; Olli Simell; Mikael Knip
Short-term exclusive breastfeeding predisposes young children with increased genetic risk of Type I diabetes to progressive beta-cell autoimmunity.
Diabetologia 2001;44(1):63-9.
2001: Petri Kulmala; Jukka Rahko; Kaisa Savola; Paula Vähäsalo; Minna Sjöroos; A Reunanen; Jorma Ilonen; Mikael Knip
Beta-cell autoimmunity, genetic susceptibility, and progression to type 1 diabetes in unaffected schoolchildren.
Diabetes care 2001;24(1):171-3.
2000: A Zavialov; Matti Ankelo; Annette Westerlund-Karlsson; Mikael Knip; Jorma Ilonen; Ari E Hinkkanen
Novel fusion proteins in the analysis of diabetes-associated autoantibodies to GAD65 and IA-2.
Journal of immunological methods 2000;246(1-2):91-6.
2000: Sergey Nejentsev; Zsofia Gombos; Antti-Pekka Laine; Riitta Veijola; Mikael Knip; Olli Simell; O Vaarala; Hans K Akerblom; Jorma Ilonen
Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B.
Diabetes 2000;49(12):2217-21.
2000: Johanna Paronen; Mikael Knip; Erkki Savilahti; Suvi M Virtanen; Jorma Ilonen; Hans K Akerblom; Outi Vaarala
Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.
Diabetes 2000;49(10):1657-65.
2000: E Sabbah; Kaisa Savola; Tapani Ebeling; Petri Kulmala; Paula Vähäsalo; Jorma Ilonen; Pasi Salmela; Mikael Knip
Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes.
Diabetes care 2000;23(9):1326-32.
2000: Jorma Ilonen; Helena Reijonen; A Green; A Reunanen; Mikael Knip; Olli Simell; Hans K Akerblom
Geographical differences within Finland in the frequency of HLA-DQ genotypes associated with type 1 diabetes susceptibility. The Childhood Diabetes in Finland Study Group.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2000;27(4):225-30.
2000: Maria Lönnrot; K Korpela; Mikael Knip; Jorma Ilonen; Olli Simell; Sari Korhonen; Kaisa Savola; P Muona; Tuula Simell; Pentti Koskela; Heikki Hyöty
Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: the Finnish Diabetes Prediction and Prevention Study.
Diabetes 2000;49(8):1314-8.
2000: S Juhela; Heikki Hyöty; Merja Roivainen; Taina Härkönen; Anne Putto-Laurila; Olli Simell; Jorma Ilonen
T-cell responses to enterovirus antigens in children with type 1 diabetes.
Diabetes 2000;49(8):1308-13.
2000: Sergey Nejentsev; Antti-Pekka Laine; Olli Simell; Jorma Ilonen
Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism: no association with type 1 diabetes among Finns.
Tissue antigens 2000;55(6):568-70.
2000: Suvi M Virtanen; Esa Läärä; Elina Hyppönen; Helena Reijonen; Leena Räsänen; A Aro; Mikael Knip; Jorma Ilonen; Hans K Akerblom
Cow's milk consumption, HLA-DQB1 genotype, and type 1 diabetes: a nested case-control study of siblings of children with diabetes. Childhood diabetes in Finland study group.
Diabetes 2000;49(6):912-7.
2000: Petri Kulmala; Jukka Rahko; Kaisa Savola; Paula Vähäsalo; Riitta Veijola; Minna Sjöroos; A Reunanen; Jorma Ilonen; Mikael Knip
Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren.
Diabetologia 2000;43(4):457-64.
2000: Teija Kimpimäki; Petri Kulmala; Kaisa Savola; Paula Vähäsalo; Helena Reijonen; Jorma Ilonen; Hans K Akerblom; Mikael Knip
Disease-associated autoantibodies as surrogate markers of type 1 diabetes in young children at increased genetic risk. Childhood Diabetes in Finland Study Group.
The Journal of clinical endocrinology and metabolism 2000;85(3):1126-32.
2000: S Laivoranta-Nyman; Timo Möttönen; Reijo Luukkainen; Markku Hakala; U Yli-Kerttula; Pekka Hannonen; J Tuokko; Auli Toivanen; Jorma Ilonen
Immunogenetic differences between patients with familial and non-familial rheumatoid arthritis.
Annals of the rheumatic diseases 2000;59(3):173-7.
2000: P Klemetti; P Björses; Tiinamaija Tuomi; Jaakko Perheentupa; Jukka Partanen; N Rautonen; A Hinkkanen; Jorma Ilonen; Outi Vaarala
Autoimmunity to glutamic acid decarboxylase in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Clinical and experimental immunology 2000;119(3):419-25.
2000: Petri Kulmala; Kaisa Savola; Helena Reijonen; Riitta Veijola; Paula Vähäsalo; J Karjalainen; Eva Tuomilehto-Wolf; Jorma Ilonen; Jaakko Tuomilehto; Hans K Akerblom; Mikael Knip
Genetic markers, humoral autoimmunity, and prediction of type 1 diabetes in siblings of affected children. Childhood Diabetes in Finland Study Group.
Diabetes 2000;49(1):48-58.
1999: Sergey Nejentsev; Minna Sjöroos; Tero Soukka; Mikael Knip; Olli Simell; Timo Lövgren; Jorma Ilonen
Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci.
Diabetic medicine : a journal of the British Diabetic Association 1999;16(12):985-92.
1999: Jorma Komulainen; Petri Kulmala; Kaisa Savola; Raisa Lounamaa; Jorma Ilonen; Helena Reijonen; Mikael Knip; Hans K Akerblom
Clinical, autoimmune, and genetic characteristics of very young children with type 1 diabetes. Childhood Diabetes in Finland (DiMe) Study Group.
Diabetes care 1999;22(12):1950-5.
1999: P Klemetti; Heikki Hyöty; Merja Roivainen; Jorma Ilonen; Kaisa Savola; Mikael Knip; Hans K Akerblom; Outi Vaarala
Relation between T-cell responses to glutamate decarboxylase and coxsackievirus B4 in patients with insulin-dependent diabetes mellitus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 1999;14(2):95-105.
1999: Mika J Mäkelä; Markus Halminen; Olli Ruuskanen; Tuomo Puhakka; Jaana Pirhonen; Ilkka Julkunen; Jorma Ilonen
Lack of induction by rhinoviruses of systemic type I interferon production or enhanced MxA protein expression during the common cold.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1999;18(9):665-8.
1999: Jane Marttila; Jorma Ilonen; E Norrby; Aimo A Salmi
Characterization of T cell epitopes in measles virus nucleoprotein.
The Journal of general virology 1999;80 ( Pt 7)():1609-15.
1999: S Juhela; Heikki Hyöty; Raivo Uibo; S H Meriste; Oivi Uibo; Maria Lönnrot; Markus Halminen; Olli Simell; Jorma Ilonen
Comparison of enterovirus-specific cellular immunity in two populations of young children vaccinated with inactivated or live poliovirus vaccines.
Clinical and experimental immunology 1999;117(1):100-5.
1999: Outi Vaarala; Mikael Knip; Johanna Paronen; Anu-Maaria Hämäläinen; P Muona; M Väätäinen; Jorma Ilonen; Olli Simell; Hans K Akerblom
Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes.
Diabetes 1999;48(7):1389-94.
1999: S Juhela; Heikki Hyöty; Ari E Hinkkanen; John Elliott; J Elliott; Merja Roivainen; Petri Kulmala; Jukka Rahko; Mikael Knip; Jorma Ilonen
T cell responses to enterovirus antigens and to beta-cell autoantigens in unaffected children positive for IDDM-associated autoantibodies.
Journal of autoimmunity 1999;12(4):269-78.
1999: E Sabbah; Kaisa Savola; Petri Kulmala; Helena Reijonen; Riitta Veijola; Paula Vähäsalo; J Karjalainen; Jorma Ilonen; Hans K Akerblom; Mikael Knip
Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group.
Clinical and experimental immunology 1999;116(1):78-83.
1999: Erkki Savilahti; Timo Ormälä; Tero Saukkonen; U Sandini-Pohjavuori; Jussi M Kantele; András Arató; Jorma Ilonen; Hans K Akerblom
Jejuna of patients with insulin-dependent diabetes mellitus (IDDM) show signs of immune activation.
Clinical and experimental immunology 1999;116(1):70-7.
1999: Jorma Ilonen; Hans K Akerblom
New technologies and genetics of type 1 diabetes.
Diabetes technology & therapeutics 1999;1(2):205-7.
1999: P Kerokoski; Jorma Ilonen; Roger Gaedigk; H M Dosch; Mikael Knip; M Hakala; Ari E Hinkkanen
Production of the islet cell antigen ICA69 (p69) with baculovirus expression system: analysis with a solid-phase time-resolved fluorescence method of sera from patients with IDDM and rheumatoid arthritis.
Autoimmunity 1999;29(4):281-9.
1999: Markus Halminen; Minna Sjöroos; Mika J Mäkelä; Matti Waris; Erkki O Terho; Timo Lövgren; Jorma Ilonen
Simultaneous detection of IFN-gamma and IL-4 mRNAs using RT-PCR and time-resolved fluorometry.
Cytokine 1999;11(1):87-93.
1998: Sergey Nejentsev; S Koskinen; Minna Sjöroos; Helena Reijonen; EI Schwartz; L Kovalchuk; A Sochnev; B Adojaan; Toomas Podar; Mikael Knip; Olli Simell; M Koskenvuo; Hans K Akerblom; Jorma Ilonen
Distribution of insulin-dependent diabetes mellitus (IDDM)-related HLA alleles correlates with the difference in IDDM incidence in four populations of the Eastern Baltic region.
Tissue antigens 1998;52(5):473-7.
1998: J Tuokko; S Koskinen; P Westman; U Yli-Kerttula; Auli Toivanen; Jorma Ilonen
Tumour necrosis factor microsatellites in reactive arthritis.
British journal of rheumatology 1998;37(11):1203-6.
1998: Kaisa Savola; E Sabbah; Petri Kulmala; Paula Vähäsalo; Jorma Ilonen; Mikael Knip
Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children.
Diabetologia 1998;41(11):1293-7.
1998: Lasse Välimaa; Minna Sjöroos; Marko Luhtala; Paavo Toivanen; Timo Lövgren; Jorma Ilonen
Detection of HLA-B27 alleles by group-specific amplification and time-resolved fluorometry.
Journal of immunological methods 1998;219(1-2):131-7.
1998: Timo Möttönen; Leena Paimela; Marjatta Leirisalo-Repo; Hannu Kautiainen; Jorma Ilonen; Pekka Hannonen
Only high disease activity and positive rheumatoid factor indicate poor prognosis in patients with early rheumatoid arthritis treated with "sawtooth" strategy.
Annals of the rheumatic diseases 1998;57(9):533-9.
1998: Minna Sjöroos; Jorma Ilonen; Helena Reijonen; Timo Lövgren
Time-resolved fluorometry based sandwich hybridisation assay for HLA-DQA1 typing.
Disease markers 1998;14(1):9-19.
1998: Jorma Ilonen; O Simell; Mikael Knip; Hans K Akerblom
Screening for genetic IDDM risk and prevention trials in infancy.
Diabetes/metabolism reviews 1998;14(2):188.
1998: Jorma Komulainen; Mikael Knip; E Sabbah; Paula Vähäsalo; Raisa Lounamaa; Hans K Akerblom; Helena Reijonen; Jorma Ilonen
Autoimmune and clinical characteristics of type I diabetes in children with different genetic risk loads defined by HLA-DQB1 alleles. Childhood Diabetes in Finland Study Group.
Clinical science (London, England : 1979) 1998;94(3):263-9.
1998: S Juhela; Heikki Hyöty; Maria Lönnrot; Merja Roivainen; Olli Simell; Jorma Ilonen
Enterovirus infections and enterovirus specific T-cell responses in infancy.
Journal of medical virology 1998;54(3):226-32.
1998: J Tuokko; E Pushnova; U Yli-Kerttula; Auli Toivanen; Jorma Ilonen
TAP2 alleles in inflammatory arthritis.
Scandinavian journal of rheumatology 1998;27(3):225-9.
1998: Jarmo Hahl; Tuula Simell; Jorma Ilonen; Mikael Knip; Olli Simell
Costs of predicting IDDM.
Diabetologia 1998;41(1):79-85.
1998: Tero Saukkonen; Suvi M Virtanen; M Karppinen; Helena Reijonen; Jorma Ilonen; Leena Räsänen; Hans K Akerblom; Erkki Savilahti
Significance of cow's milk protein antibodies as risk factor for childhood IDDM: interactions with dietary cow's milk intake and HLA-DQB1 genotype. Childhood Diabetes in Finland Study Group.
Diabetologia 1998;41(1):72-8.
1998: P Klemetti; Erkki Savilahti; Jorma Ilonen; Hans K Akerblom; Outi Vaarala
T-cell reactivity to wheat gluten in patients with insulin-dependent diabetes mellitus.
Scandinavian journal of immunology 1998;47(1):48-53.
1997: Sergey Nejentsev; Helena Reijonen; B Adojaan; L Kovalchuk; A Sochnevs; EI Schwartz; Hans K Akerblom; Jorma Ilonen
The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302.
Diabetes 1997;46(11):1888-92.
1997: Helena Reijonen; Sergey Nejentsev; J Tuokko; S Koskinen; Eva Tuomilehto-Wolf; Hans K Akerblom; Jorma Ilonen
HLA-DR4 subtype and -B alleles in DQB1*0302-positive haplotypes associated with IDDM. The Childhood Diabetes in Finland Study Group.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1997;24(5):357-63.
1997: Markus Halminen; P Klemetti; Outi Vaarala; Mikko Hurme; Jorma Ilonen
Interferon-gamma production in antigen specific T cell response: quantitation of specific mRNA and secreted protein.
Scandinavian journal of immunology 1997;46(4):388-92.
1997: Aura Falck; J M Knip; Jorma Ilonen; LT Laatikainen
Genetic markers in early diabetic retinopathy of adolescents with type I diabetes.
Journal of diabetes and its complications 1997;11(4):203-7.
1997: Jorma Ilonen; S Koskinen; Sergey Nejentsev; Minna Sjöroos; Mikael Knip; EI Schwartz; B Adojaan; L Kovalchuk; A Sochnevs
HLA-DQB1*0304-DRB1*0408 haplotype associated with insulin-dependent diabetes mellitus in populations in the eastern Baltic region.
Tissue antigens 1997;49(5):532-4.
1997: Markus Halminen; Jorma Ilonen; Ilkka Julkunen; Olli Ruuskanen; Olli Simell; Mika J Mäkelä
Expression of MxA protein in blood lymphocytes discriminates between viral and bacterial infections in febrile children.
Pediatric research 1997;41(5):647-50.
1997: M Hiltunen; Heikki Hyöty; Mikael Knip; Jorma Ilonen; Helena Reijonen; Paula Vähäsalo; Merja Roivainen; M Lonnrot; Pauli Leinikki; Tapani Hovi; Hans K Akerblom
Islet cell antibody seroconversion in children is temporally associated with enterovirus infections. Childhood Diabetes in Finland (DiMe) Study Group.
The Journal of infectious diseases 1997;175(3):554-60.
1997: J Tuokko; Helena Reijonen; Jorma Ilonen; K Anttila; Seppo T Nikkari; Timo Möttönen; U Yli-Kerttula; Auli Toivanen
Increase of HLA-DRB1*0408 and -DQB1*0301 in HLA-B27 positive reactive arthritis.
Annals of the rheumatic diseases 1997;56(1):37-40.
1997: Pärt Peterson; H Salmi; Heikki Hyöty; A Miettinen; Jorma Ilonen; Helena Reijonen; Mikael Knip; H K Akerblom; Kai Krohn
Steroid 21-hydroxylase autoantibodies in insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group.
Clinical immunology and immunopathology 1997;82(1):37-42.
1996: O Oksaranta; S Tarvonen; Jorma Ilonen; K Poikonen; M Reunanen; M Panelius; Reijo Salonen
T-cell subpopulations in the cerebrospinal fluid and peripheral blood of patients with multiple sclerosis: a follow-up study.
Neurology 1996;47(6):1542-5.
1996: Riitta Veijola; Helena Reijonen; Paula Vähäsalo; E Sabbah; Petri Kulmala; Jorma Ilonen; Hans K Akerblom; Mikael Knip
HLA-DQB1-defined genetic susceptibility, beta cell autoimmunity, and metabolic characteristics in familial and nonfamilial insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group.
The Journal of clinical investigation 1996;98(11):2489-95.
1996: A Martikainen; Tero Saukkonen; Petri Kulmala; Helena Reijonen; Jorma Ilonen; K Teramo; P Koskela; Mikael Knip; Hans K Akerblom
Disease-associated antibodies in offspring of mothers with IDDM.
Diabetes 1996;45(12):1706-10.
1996: Markus Halminen; Riitta Veijola; Helena Reijonen; Jorma Ilonen; Hans K Akerblom; Mikael Knip
Effect of polymorphism in the insulin gene region on IDDM susceptibility and insulin secretion. The Childhood Diabetes in Finland (DiMe) Study Group.
European journal of clinical investigation 1996;26(10):847-52.
1996: Merja Soilu-Hänninen; Arno Hänninen; Jorma Ilonen; A Salmi; Reijo Salonen
Measles virus hemagglutinin mediates monocyte aggregation and increased adherence to measles-infected endothelial cells.
Medical microbiology and immunology 1996;185(2):73-80.
1996: Jorma Ilonen; Helena Reijonen; E Herva; Minna Sjöroos; A Iitiä; Timo Lövgren; Riitta Veijola; Mikael Knip; Hans K Akerblom
Rapid HLA-DQB1 genotyping for four alleles in the assessment of risk for IDDM in the Finnish population. The Childhood Diabetes in Finland (DiMe) Study Group.
Diabetes care 1996;19(8):795-800.
1996: Riitta Veijola; Mikael Knip; R Puukka; Helena Reijonen; D W Cox; Jorma Ilonen
The immunoglobulin heavy-chain variable region in insulin-dependent diabetes mellitus: affected-sib-pair analysis and association studies.
American journal of human genetics 1996;59(2):462-70.
1996: J Marttila; Jorma Ilonen; M Lehtinen; P Parkkonen; A Salmi
Definition of three minimal T helper cell epitopes of rubella virus E1 glycoprotein.
Clinical and experimental immunology 1996;104(3):394-7.
1996: Tero Saukkonen; Erkki Savilahti; Helena Reijonen; Jorma Ilonen; Eva Tuomilehto-Wolf; Hans K Akerblom
Coeliac disease: frequent occurrence after clinical onset of insulin-dependent diabetes mellitus. Childhood Diabetes in Finland Study Group.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(5):464-70.
1996: Outi Vaarala; P Klemetti; Erkki Savilahti; Helena Reijonen; Jorma Ilonen; Hans K Akerblom
Cellular immune response to cow's milk beta-lactoglobulin in patients with newly diagnosed IDDM.
Diabetes 1996;45(2):178-82.
1995: O Oksaranta; S Tarvonen; Jorma Ilonen; K Poikonen; M Reunanen; M Panelius; Reijo Salonen
Influx of nonactivated T lymphocytes into the cerebrospinal fluid during relapse of multiple sclerosis.
Annals of neurology 1995;38(3):465-8.
1995: Riitta Veijola; Paula Vähäsalo; Eva Tuomilehto-Wolf; Helena Reijonen; Petri Kulmala; Jorma Ilonen; Hans K Akerblom; Mikael Knip
Human leukocyte antigen identity and DQ risk alleles in autoantibody-positive siblings of children with IDDM are associated with reduced early insulin response. Childhood Diabetes in Finland (DiMe) Study Group.
Diabetes 1995;44(9):1021-8.
1995: Minna Sjöroos; A Iitiä; Jorma Ilonen; Helena Reijonen; Timo Lövgren
Triple-label hybridization assay for type-1 diabetes-related HLA alleles.
BioTechniques 1995;18(5):870-7.
1994: J P Erälinna; Merja Soilu-Hänninen; Matias Röyttä; Jorma Ilonen; A Mäkelä; Reijo Salonen
Facilitation of experimental allergic encephalomyelitis by irradiation and virus infection: role of inflammatory cells.
Journal of neuroimmunology 1994;55(1):81-90.
1994: Helena Reijonen; Paula Vähäsalo; J Karjalainen; Jorma Ilonen; Hans K Akerblom; Mikael Knip
HLA-DQB1 genotypes and islet cell antibodies in the identification of siblings at risk for insulin-dependent diabetes (IDDM) in Finland. Childhood Diabetes in Finland (DiMe) Study Group.
Journal of autoimmunity 1994;7(5):675-86.
1994: M Hietarinta; Jorma Ilonen; Olli Lassila; A Hietaharju
Association of HLA antigens with anti-Scl-70-antibodies and clinical manifestations of systemic sclerosis (scleroderma)
British journal of rheumatology 1994;33(4):323-6.
1994: P Parkkonen; Heikki Hyöty; Jorma Ilonen; Helena Reijonen; S Ylä-Herttuala; P Leinikki
Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 beta chain. Childhood Diabetes in Finland Study Group.
Clinical and experimental immunology 1994;95(2):287-93.
1994: Helena Reijonen; Jorma Ilonen; Mikael Knip
[The role of genes in the type-1 diabetes].
Duodecim; lääketieteellinen aikakauskirja 1994;110(7):695-706.
1994: Helena Reijonen; Jorma Ilonen; Hans K Akerblom; Mikael Knip; H M Dosch
Multi-locus analysis of HLA class II genes in DR2-positive IDDM haplotypes in Finland. The "Childhood Diabetes in Finland" (DiMe) Study Group.
Tissue antigens 1994;43(1):1-6.
1993: Hans K Akerblom; Erkki Savilahti; Tero Saukkonen; A Paganus; Suvi M Virtanen; K Teramo; Mikael Knip; Jorma Ilonen; Helena Reijonen; J Karjalainen
The case for elimination of cow's milk in early infancy in the prevention of type 1 diabetes: the Finnish experience.
Diabetes/metabolism reviews 1993;9(4):269-78.
1993: Riitta Veijola; Mikael Knip; Leila Risteli; Juha Risteli; M L Käär; R Puukka; Jorma Ilonen
Clinical characteristics and circulating collagen and laminin metabolites in insulin-dependent diabetic children with joint and skin manifestations.
Pediatric research 1993;33(5):501-5.
1993: R Leopardi; Jorma Ilonen; Leena Mattila; Aimo A Salmi
Effect of measles virus infection on MHC class II expression and antigen presentation in human monocytes.
Cellular immunology 1993;147(2):388-96.
1993: Mika J Mäkelä; Jorma Ilonen; Aimo A Salmi
Antibody and T cell responses to measles virus polypeptides and synthetic peptides.
FEMS immunology and medical microbiology 1993;6(1):3-11.
1992: Jorma Ilonen; H Merivuori; Helena Reijonen; Mikael Knip; Hans K Akerblom; Flemming Pociot; J Nerup
Tumour necrosis factor-beta gene RFLP alleles in Finnish IDDM haplotypes. The Childhood Diabetes in Finland (DiMe) Study Group.
Scandinavian journal of immunology 1992;36(6):779-83.
1992: A Hietaharju; Markku Korpela; Jorma Ilonen; H Frey
Nervous system disease, immunological features, and HLA phenotype in Sjögren's syndrome.
Annals of the rheumatic diseases 1992;51(4):506-9.
1992: P Ruuska; R Hämeenkorpi; S Forsberg; Heikki Julkunen; R Mäkitalo; Jorma Ilonen; Anja Tiilikainen
Differences in HLA antigens between patients with mixed connective tissue disease and systemic lupus erythematosus.
Annals of the rheumatic diseases 1992;51(1):52-5.
1992: Jorma Ilonen; H Seppänen; Ale Närvänen; M Korkolainen; Aimo A Salmi
Recognition of synthetic peptides with sequences of rubella virus E1 polypeptide by antibodies and T lymphocytes.
Viral immunology 1992;5(3):221-8.
1992: R Salonen; Jorma Ilonen
[Abnormalities in the immune system of MS patients and possibilities of immunological treatment].
Duodecim; lääketieteellinen aikakauskirja 1992;108(1):82-92.
1991: Helena Reijonen; Jorma Ilonen; Mikael Knip; Hans K Akerblom
HLA-DQB1 alleles and absence of Asp 57 as susceptibility factors of IDDM in Finland.
Diabetes 1991;40(12):1640-4.
1991: Jorma Ilonen; Heljä-Marja Surcel; M L Käär
Abnormalities within CD4 and CD8 T lymphocytes subsets in type 1 (insulin-dependent) diabetes.
Clinical and experimental immunology 1991;85(2):278-81.
1991: Helena Reijonen; Jorma Ilonen; Mikael Knip; T Reunala
Insulin-dependent diabetes mellitus associated with dermatitis herpetiformis: evidence for heterogeneity of HLA-associated genes.
Tissue antigens 1991;37(2):94-6.
1991: Jorma Ilonen; Markku Hakala; Helena Reijonen; A Tiilikainen
B27-bearing HLA haplotypes in rheumatoid arthritis: characterization in Finnish patients.
Human immunology 1991;30(1):7-10.
1990: Helena Reijonen; Sylvi Silvennoinen-Kassinen; Jorma Ilonen; Mikael Knip
Lack of association of T cell receptor beta-chain constant region polymorphism with insulin-dependent diabetes mellitus in Finland.
Clinical and experimental immunology 1990;81(3):396-9.
1990: Jorma Ilonen; Mika J Mäkelä; B Ziola; Aimo A Salmi
Cloning of human T cells specific for measles virus haemagglutinin and nucleocapsid.
Clinical and experimental immunology 1990;81(2):212-7.
1990: I Jokinen; K Poikonen; Timo Möttönen; Pekka Hannonen; M Oka; Jorma Ilonen; Heljä-Marja Surcel; R Karttunen; H Arvilommi
Analysis of impaired in vitro immunoglobulin synthesis in rheumatoid arthritis.
Annals of the rheumatic diseases 1990;49(7):507-11.
1990: Jorma Ilonen; Helena Reijonen; H Arvilommi; I Jokinen; Timo Möttönen; Pekka Hannonen
HLA-DR antigens and HLA-DQ beta chain polymorphism in susceptibility to rheumatoid arthritis.
Annals of the rheumatic diseases 1990;49(7):494-6.
1990: Helena Reijonen; Jorma Ilonen; Mikael Knip; B Michelsen; Hans K Akerblom
HLA-DQ beta-chain restriction fragment length polymorphism as a risk marker in type 1 (insulin-dependent) diabetes mellitus: a Finnish family study.
Diabetologia 1990;33(6):357-62.
1990: Jorma Ilonen; Heljä-Marja Surcel; H Jägerroos; T Nurmi; M Reunanen
T-lymphocyte subsets defined by double immunofluorescence in multiple sclerosis.
Acta neurologica Scandinavica 1990;81(2):128-30.
1989: Jorma Ilonen; R Salonen; A Salmi; A Mustonen
Low levels of mumps virus antigen induced interferon-alpha production in insulin-dependent diabetes.
Diabetes research (Edinburgh, Scotland) 1989;12(2):75-8.
1989: Heljä-Marja Surcel; Jorma Ilonen; K Poikonen; Elja Herva
Francisella tularensis-specific T-cell clones are human leukocyte antigen class II restricted, secrete interleukin-2 and gamma interferon, and induce immunoglobulin production.
Infection and immunity 1989;57(9):2906-8.
1989: Aimo A Salmi; T Hyypiä; Jorma Ilonen; M Reunanen; M Remes
Production of viral antibodies in vitro by CSF cells from mumps meningitis and multiple sclerosis patients.
Journal of the neurological sciences 1989;90(3):315-24.
1989: Reijo Salonen; Jorma Ilonen; H Jägerroos; H Syrjälä; T Nurmi; M Reunanen
Lymphocyte subsets in the cerebrospinal fluid in active multiple sclerosis.
Annals of neurology 1989;25(5):500-2.
1989: J Karjalainen; P Salmela; Jorma Ilonen; Heljä-Marja Surcel; Mikael Knip
A comparison of childhood and adult type I diabetes mellitus.
The New England journal of medicine 1989;320(14):881-6.
1989: R Salonen; Jorma Ilonen; Aimo A Salmi
Measles virus inhibits lymphocyte proliferation in vitro by two different mechanisms.
Clinical and experimental immunology 1989;75(3):376-80.
1989: S Vydelingum; Jorma Ilonen; R Salonen; Raymond Marusyk; A Salmi
Infection of human peripheral blood mononuclear cells with a temperature-sensitive mutant of measles virus.
Journal of virology 1989;63(2):689-95.
1988: Heikki Hyöty; P Leinikki; A Reunanen; Jorma Ilonen; Heljä-Marja Surcel; A Rilva; M L Käär; T Huupponen; A Hakulinen; A L Mäkelä
Mumps infections in the etiology of type 1 (insulin-dependent) diabetes.
Diabetes research (Edinburgh, Scotland) 1988;9(3):111-6.
1988: L X Wu; Jorma Ilonen; Mika J Mäkelä; R Salonen; Raymond Marusyk; Aimo A Salmi
Impaired interleukin 1 and interleukin 2 production following in vitro abortive infection of murine spleen mononuclear cells by Semliki Forest virus.
Cellular immunology 1988;116(1):112-22.
1988: Heljä-Marja Surcel; Jorma Ilonen; M L Käär; Heikki Hyöty; P Leinikki
Infection by multiple viruses and lymphocyte abnormalities at the diagnosis of diabetes.
Acta paediatrica Scandinavica 1988;77(3):471-4.
1988: J Karjalainen; Mikael Knip; Heikki Hyöty; P Leinikki; Jorma Ilonen; M L Käär; Hans K Akerblom
Relationship between serum insulin autoantibodies, islet cell antibodies and Coxsackie-B4 and mumps virus-specific antibodies at the clinical manifestation of type 1 (insulin-dependent) diabetes.
Diabetologia 1988;31(3):146-52.
1988: R Salonen; Jorma Ilonen; A Salmi
Measles virus infection of unstimulated blood mononuclear cells in vitro: antigen expression and virus production preferentially in monocytes.
Clinical and experimental immunology 1988;71(2):224-8.
1988: Jorma Ilonen; R Salonen; Raymond Marusyk; A Salmi
Measles virus strain-dependent variation in outcome of infection of human blood mononuclear cells.
The Journal of general virology 1988;69 ( Pt 1)():247-52.
1987: J Partanen; A H van Assendelft; S Koskimies; S Forsberg; Markku Hakala; Jorma Ilonen
Patients with rheumatoid arthritis and gold-induced pneumonitis express two high-risk major histocompatibility complex patterns.
Chest 1987;92(2):277-81.
1987: Heljä-Marja Surcel; R Karttunen; Jorma Ilonen; M L Käär
Lymphocyte responsiveness and interleukin 2 production in type 1 (insulin-dependent) diabetes mellitus.
Journal of clinical & laboratory immunology 1987;22(4):163-4.
1987: Jorma Ilonen; T Nurmi; M Reunanen; A Salmi
NK activity and NK-like non-specific cytolysis after PPD, rubella and measles antigen stimulation in multiple sclerosis.
Journal of the neurological sciences 1987;77(1):77-85.
1987: Jorma Ilonen; K Cantell; M Reunanen; M Panelius; B Ziola; G Lund; A Salmi
Immunological findings during an acute relapse of subacute sclerosing panencephalitis in a patient with an unusually prolonged disease course.
Journal of clinical & laboratory immunology 1987;22(1):41-7.
1986: Markku Hakala; A H van Assendelft; Jorma Ilonen; S Jalava; Anja Tiilikainen
Association of different HLA antigens with various toxic effects of gold salts in rheumatoid arthritis.
Annals of the rheumatic diseases 1986;45(3):177-82.
1986: Markku Hakala; P Ruuska; R Hämeenkorpi; Anja Tiilikainen; Jorma Ilonen; R Mäkitalo
Diffuse interstitial lung disease in rheumatoid arthritis. Views on immunological and HLA findings.
Scandinavian journal of rheumatology 1986;15(4):368-76.
1986: Markku Hakala; Anja Tiilikainen; R Hämeenkorpi; Jorma Ilonen; S Jalava; P Ruuska; R Mäkitalo
Rheumatoid arthritis with pleural effusion includes a subgroup with autoimmune features and HLA-B8, Dw3 association.
Scandinavian journal of rheumatology 1986;15(3):290-6.
1985: R Karttunen; Jorma Ilonen; Elja Herva
Interleukin 2 production in whole blood culture: a rapid test of immunity to Francisella tularensis.
Journal of clinical microbiology 1985;22(2):318-9.
1985: A Mustonen; Jorma Ilonen; A Tiilikainen; M Kataja; H K Akerblom
An analysis of epidemiological data in HLA-typed diabetic children.
Diabetologia 1985;28(7):397-400.
1984: P Ruuska; Jorma Ilonen; A Mustonen; Anja Tiilikainen
Defective erythrocyte C3b receptor function associated with low serum complement (C3, C4) concentrations in insulin-dependent diabetes mellitus.
Clinical and experimental immunology 1984;57(1):12-6.
1984: R Karttunen; T Nurmi; Jorma Ilonen; Heljä-Marja Surcel
Cell-mediated immunodeficiency in Down's syndrome: normal IL-2 production but inverted ratio of T cell subsets.
Clinical and experimental immunology 1984;55(2):257-63.
1984: Jorma Ilonen; A Mustonen; H K Akerblom; K Kouvalainen
Immunological features in the course of type 1 diabetes.
Annals of clinical research 1984;16(2):64-73.
1983: Jorma Ilonen; M Reunanen; A Salmi; E Herva
Lymphocyte blast transformation responses to mitogens and specific antigens in different clinical phases of multiple sclerosis: a follow-up study.
Acta neurologica Scandinavica 1983;68(1):1-12.
1983: A Salmi; M Reunanen; Jorma Ilonen; M Panelius
Intrathecal antibody synthesis to virus antigens in multiple sclerosis.
Clinical and experimental immunology 1983;52(2):241-9.
1983: M Reunanen; Jorma Ilonen; T Arnadottir; A Ahonen; A Salmi
Mitogen and antigen stimulation of multiple sclerosis cerebrospinal fluid lymphocytes in vitro.
Journal of the neurological sciences 1983;58(2):211-21.
1982: A Mustonen; Jorma Ilonen; H K Akerblom; Anja Tiilikainen
An islet cell antibody negative form of insulin-dependent diabetes mellitus (IDD) associated with HLA antigens A9 and Bw16.
Clinical and experimental immunology 1982;48(1):213-7.
1980: M Reunanen; A Salmi; Jorma Ilonen; E Herva
Proliferation of multiple sclerosis cerebrospinal fluid lymphocytes after stimulation with measles virus antigens.
Acta neurologica Scandinavica 1980;62(5):293-9.
1980: Jorma Ilonen; M Reunanen; E Herva; B Ziola; A Salmi
Stimulation of lymphocytes from subacute sclerosing panencephalitis patients by defined measles virus antigens.
Cellular immunology 1980;51(2):201-14.
1980: Jorma Ilonen; E Herva; Anja Tiilikainen; H K Akerblom; A Mustonen; T Koivukangas; K Kouvalainen
HLA genetics of insulin-dependent juvenile-onset diabetes mellitus in northern Finland.
Tissue antigens 1980;15(4):381-8.