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Toshio Imai

Research Profile

Chemicals & Drugs

Anatomy

Cell Line

Physiology

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Publications

TOP 3
Osamu Yoneda; Toshio Imai; Miyuki Nishimura; Michihiko Miyaji; Tsuneyo Mimori; Toshiro Okazaki; Naochika Domae; Hiroko Fujimoto; Yasuhiro Minami; Takeshi Kono; Eda T Bloom; Hisanori Umehara
Membrane-bound form of fractalkine induces IFN-gamma production by NK cells.
Miyuki Nishimura; Hisanori Umehara; Takashi Nakayama; Osamu Yoneda; Kunio Hieshima; Mayumi Kakizaki; Naochika Dohmae; Osamu Yoshie; Toshio Imai
Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression.
Hisanori Umehara; Seiji Goda; Toshio Imai; Yutaka Nagano; Yasuhiro Minami; Y Tanaka; Toshiro Okazaki; Eda T Bloom; Naochika Domae
Fractalkine, a CX3C-chemokine, functions predominantly as an adhesion molecule in monocytic cell line THP-1.

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All Publications

2003: Osamu Yoneda; Toshio Imai; Miyuki Nishimura; Michihiko Miyaji; Tsuneyo Mimori; Toshiro Okazaki; Naochika Domae; Hiroko Fujimoto; Yasuhiro Minami; Takeshi Kono; Eda T Bloom; Hisanori Umehara
Membrane-bound form of fractalkine induces IFN-gamma production by NK cells.
European journal of immunology 2003;33(1):53-8.
2002: Miyuki Nishimura; Hisanori Umehara; Takashi Nakayama; Osamu Yoneda; Kunio Hieshima; Mayumi Kakizaki; Naochika Dohmae; Osamu Yoshie; Toshio Imai
Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6173-80.
2001: Hisanori Umehara; Seiji Goda; Toshio Imai; Yutaka Nagano; Yasuhiro Minami; Y Tanaka; Toshiro Okazaki; Eda T Bloom; Naochika Domae
Fractalkine, a CX3C-chemokine, functions predominantly as an adhesion molecule in monocytic cell line THP-1.
Immunology and cell biology 2001;79(3):298-302.
2000: Seiji Goda; Toshio Imai; Osamu Yoshie; Osamu Yoneda; Hiroshi Inoue; Yutaka Nagano; Toshiro Okazaki; Hisao Imai; Eda T Bloom; Naochika Domae; Hisanori Umehara
CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4313-20.
2000: Osamu Yoneda; Toshio Imai; Seiji Goda; Hiroshi Inoue; A Yamauchi; Toshiro Okazaki; Hisao Imai; Osamu Yoshie; Eda T Bloom; Naochika Domae; Hisanori Umehara
Fractalkine-mediated endothelial cell injury by NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4055-62.
1999: M Nagira; A Sato; S Miki; Toshio Imai; Osamu Yoshie
Enhanced HIV-1 replication by chemokines constitutively expressed in secondary lymphoid tissues.
Virology 1999;264(2):422-6.
1999: I Ishikawa-Mochizuki; M Kitaura; M Baba; Takashi Nakayama; Dai Izawa; Toshio Imai; H Yamada; Kunio Hieshima; R Suzuki; Hisayuki Nomiyama; Osamu Yoshie
Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of a CC chemokine encoded by molluscum contagiosum virus.
FEBS letters 1999;460(3):544-8.
1999: M Kitaura; N Suzuki; Toshio Imai; S Takagi; R Suzuki; T Nakajima; K Hirai; Hisayuki Nomiyama; Osamu Yoshie
Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.
The Journal of biological chemistry 1999;274(39):27975-80.
1999: T Yoshida; I Ishikawa; Y Ono; Toshio Imai; R Suzuki; Osamu Yoshie
An activation-responsive element in single C motif-1/lymphotactin promoter is a site of constitutive and inducible DNA-protein interactions involving nuclear factor of activated T cell.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3295-303.
1999: T Yoshida; Dai Izawa; Takashi Nakayama; K Nakahara; M Kakizaki; Toshio Imai; R Suzuki; M Miyasaka; Osamu Yoshie
Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor.
FEBS letters 1999;458(1):37-40.
1999: Y Tanaka; Toshio Imai; M Baba; I Ishikawa; Masahiro Uehira; Hisayuki Nomiyama; Osamu Yoshie
Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans.
European journal of immunology 1999;29(2):633-42.
1999: Toshio Imai; M Nagira; S Takagi; Mayumi Kakizaki; Miyuki Nishimura; J Wang; P W Gray; K Matsushima; Osamu Yoshie
Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine.
International immunology 1999;11(1):81-8.
1998: R Yoshida; M Nagira; Toshio Imai; M Baba; S Takagi; Yoichi Tabira; J Akagi; Hisayuki Nomiyama; Osamu Yoshie
EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC.
International immunology 1998;10(7):901-10.
1998: T Yoshida; Toshio Imai; Mayumi Kakizaki; Miyuki Nishimura; S Takagi; Osamu Yoshie
Identification of single C motif-1/lymphotactin receptor XCR1.
The Journal of biological chemistry 1998;273(26):16551-4.
1998: M Nagira; Toshio Imai; R Yoshida; S Takagi; M Iwasaki; M Baba; Yoichi Tabira; J Akagi; Hisayuki Nomiyama; Osamu Yoshie
A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cells.
European journal of immunology 1998;28(5):1516-23.
1998: R Yoshida; M Nagira; M Kitaura; N Imagawa; Toshio Imai; Osamu Yoshie
Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7.
The Journal of biological chemistry 1998;273(12):7118-22.
1997: Toshio Imai; Kunio Hieshima; C Haskell; M Baba; M Nagira; Miyuki Nishimura; Mayumi Kakizaki; S Takagi; Hisayuki Nomiyama; Thomas J Schall; Osamu Yoshie
Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.
Cell 1997;91(4):521-30.
1997: Osamu Yoshie; Toshio Imai; Hisayuki Nomiyama
Novel lymphocyte-specific CC chemokines and their receptors.
Journal of leukocyte biology 1997;62(5):634-44.
1997: M Nagira; Toshio Imai; Kunio Hieshima; Jun Kusuda; M Ridanpää; S Takagi; Miyuki Nishimura; Mayumi Kakizaki; Hisayuki Nomiyama; Osamu Yoshie
Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.
The Journal of biological chemistry 1997;272(31):19518-24.
1997: Toshio Imai; M Baba; Miyuki Nishimura; Mayumi Kakizaki; S Takagi; Osamu Yoshie
The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4.
The Journal of biological chemistry 1997;272(23):15036-42.
1997: M Baba; Toshio Imai; Miyuki Nishimura; Mayumi Kakizaki; S Takagi; Kunio Hieshima; Hisayuki Nomiyama; Osamu Yoshie
Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC.
The Journal of biological chemistry 1997;272(23):14893-8.
1997: R Yoshida; Toshio Imai; Kunio Hieshima; Jun Kusuda; M Baba; M Kitaura; Miyuki Nishimura; Mayumi Kakizaki; Hisayuki Nomiyama; Osamu Yoshie
Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.
The Journal of biological chemistry 1997;272(21):13803-9.