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Katsumi Imaida
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68
Shirai, Tomoyuki
45
Ito, Nobuyuki
26
Takahashi, Satoru
25
Tamano, Seiko
22
Saoo, Kousuke
20
Yokohira, Masanao
19
Asamoto, Makoto
19
Hirose, Masao
16
Matsuda, Yoko
16
Yamakawa, Keiko
12
Hosokawa, Kyoko
10
Futakuchi, Mitsuru
10
Ogawa, Kumiko
10
Takeuchi, Hijiri
9
Zeng, Yu
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All Publications
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2009: Hashimoto Nozomi; Yachida Shinichi; Okano Keiichi; Wakabayashi Hisao; Imaida Katsumi; Kurokohchi Kazutaka; Masaki Tsutomu; Kinoshita Hisoka; Tominaga Masahiro; Ajiki Tetsuo; Ku Yonson; Okabayashi Takehiro; Hanazaki Kazuhiro; Hiroi Makoto; Izumi Sadanobu; Mano Shohei; Okada Setsuo; Karasawa Yukihiko; Maeba Takashi; Suzuki Yasuyuki
Immunohistochemically detected expression of p27(Kip1) and Skp2 predicts survival in patients with intrahepatic cholangiocarcinomas.
Annals of surgical oncology 2009;16(2):395-403.
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2008: Yachida Shinichi; Sakamoto Michiie; Imaida Katsumi; Yokohira Masanao; Saoo Kousuke; Okano Keiichi; Wakabayashi Hisao; Maeta Hajime; Suzuki Yasuyuki
p27(Kip1)is overexpressed in very early stages of hepatocarcinogenesis.
Cancer science 2008;99(11):2152-9.
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2008: Kuno Toshiya; Yokohira Masanao; Matsuda Yoko; Suzuki Satoshi; Hashimoto Nozomi; Yamakawa Keiko; Saoo Kousuke; Imaida Katsumi
Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J female mice.
Oncology reports 2008;20(4):767-72.
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2008: Yokohira Masanao; Takeuchi Hijiri; Saoo Kousuke; Matsuda Yoko; Yamakawa Keiko; Hosokawa Kyoko; Kuno Toshiya; Imaida Katsumi
Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2008;60(6):469-73.
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2008: Hori Yusaku; Takasuka Nobuo; Mutoh Michihiro; Kitahashi Tsukasa; Kojima Shuji; Imaida Katsumi; Suzuki Masahiro; Kohara Kazushi; Yamamoto Shuji; Moriyama Noriyuki; Sugimura Takashi; Wakabayashi Keiji
Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography.
Cancer science 2008;99(9):1774-7.
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2008: Yokohira Masanao; Hosokawa Kyoko; Yamakawa Keiko; Hashimoto Nozomi; Suzuki Satoshi; Matsuda Yoko; Saoo Kousuke; Kuno Toshiya; Imaida Katsumi
A 90-day toxicity study of L-asparagine, a food additive, in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(7):2568-72.
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2008: Yokohira Masanao; Hosokawa Kyoko; Yamakawa Keiko; Saoo Kousuke; Matsuda Yoko; Zeng Yu; Kuno Toshiya; Imaida Katsumi
Potential inhibitory effects of D-allose, a rare sugar, on liver preneoplastic lesion development in F344 rat medium-term bioassay.
Journal of bioscience and bioengineering 2008;105(5):545-53.
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2008: Yokohira M; Yamakawa K; Hosokawa K; Matsuda Y; Kuno T; Saoo K; Imaida K
Promotion potential of madder color in a medium-term multi-organ carcinogenesis bioassay model in F344 rats.
Journal of food science 2008;73(3):T26-32.
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2008: Goto Rieko; Hoshikawa Hiroshi; Fujii Takashi; Indo Kanako; Yoshino Kunitoshi; Imaida Katsumi; Mori Nozomu
Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma.
Oncology reports 2008;19(3):645-50.
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2008: Kitahashi Tsukasa; Takahashi Mami; Yamada Yutaka; Oghiso Yoichi; Yokohira Masanao; Imaida Katsumi; Tsutsumi Masahiro; Takasuka Nobuo; Sugimura Takashi; Wakabayashi Keiji
Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors.
Cancer science 2008;99(2):241-5.
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2008: Matsuda Yoko; Yokohira Masanao; Suzuki Satoshi; Hosokawa Kyoko; Yamakawa Keiko; Zeng Yu; Ninomiya Fumiko; Saoo Kousuke; Kuno Toshiya; Imaida Katsumi
One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(2):733-9.
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2008: Ikeda Mico; Yamakawa Keiko; Saoo Kousuke; Matsuda Yoko; Hosokawa Kyoko; Takeuchi Hijiri; Li Jia-Qing; Zeng Yu; Yokohira Masanao; Imaida Katsumi
Induction of multiple granulomas in the liver with severe hepatocyte damage by montan wax, a natural food additive, in a 90-day toxicity study in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(2):654-61.
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2008: Yokohira Masanao; Kuno Toshiya; Yamakawa Keiko; Hosokawa Kyoko; Matsuda Yoko; Hashimoto Nozomi; Suzuki Satoshi; Saoo Kousuke; Imaida Katsumi
Lung toxicity of 16 fine particles on intratracheal instillation in a bioassay model using f344 male rats.
Toxicologic pathology 2008;36(4):620-31.
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2007: Matsuda Yoko; Saoo Kousuke; Yamakawa Keiko; Yokohira Masanao; Suzuki Satoshi; Kuno Toshiya; Kamataki Tetsuya; Imaida Katsumi
Overexpression of CYP2A6 in human colorectal tumors.
Cancer science 2007;98(10):1582-5.
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2007: Matsuda Yoko; Yamakawa Keiko; Saoo Kousuke; Hosokawa Kyoko; Yokohira Masanao; Kuno Toshiya; Iwai Junko; Shirai Takatoshi; Obika Kaoru; Kamataki Tetsuya; Imaida Katsumi
CYP2A6 overexpression in human lung cancers correlates with a high malignant status.
Oncology reports 2007;18(1):53-7.
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2007: Matsuda Yoko; Saoo Kousuke; Hosokawa Kyoko; Yamakawa Keiko; Yokohira Masanao; Zeng Yu; Takeuchi Hijiri; Imaida Katsumi
Post-initiation chemopreventive effects of dietary bovine lactoferrin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice.
Cancer letters 2007;246(1-2):41-6.
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2007: Yokohira Masanao; Takeuchi Hijiri; Yamakawa Keiko; Saoo Kousuke; Matsuda Yoko; Zeng Yu; Hosokawa Kyoko; Imaida Katsumi
Bioassay by intratracheal instillation for detection of lung toxicity due to fine particles in F344 male rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2007;58(4):211-21.
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2006: Kinoshita Yoshihisa; Kuratsukuri Katsuyuki; Landas Steve; Imaida Katsumi; Rovito Peter M; Wang Ching Y; Haas Gabriel P
Expression of prostate-specific membrane antigen in normal and malignant human tissues.
World journal of surgery 2006;30(4):628-36.
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2006: Takeuchi Hijiri; Saoo Kousuke; Matsuda Yoko; Yokohira Masanao; Yamakawa Keiko; Zeng Yu; Miyazaki Masafumi; Fujieda Masaki; Kamataki Tetsuya; Imaida Katsumi
Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice.
Cancer letters 2006;234(2):232-8.
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2005: Miyazaki Masafumi; Yamazaki Hiroshi; Takeuchi Hijiri; Saoo Kousuke; Yokohira Masanao; Masumura Ken-ichi; Nohmi Takehiko; Funae Yoshihiko; Imaida Katsumi; Kamataki Tetsuya
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
Carcinogenesis 2005;26(11):1947-55.
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2005: Hagiwara A; Yoshino H; Sano M; Kawabe M; Tamano S; Sakaue K; Nakamura M; Tada M; Imaida K; Shirai T
Thirteen-week feeding study of thaumatin (a natural proteinaceous sweetener), sterilized by electron beam irradiation, in Sprague-Dawley rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(8):1297-302.
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2005: Zeng Yu; Yokohira Masanao; Saoo Kousuke; Takeuchi Hijiri; Chen Yan; Yamakawa Keiko; Matsuda Yoko; Kakehi Yoshiyuki; Imaida Katsumi
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by raloxifene, an antiestrogen with anti-androgen action, but not nimesulide, a selective cyclooxygenase-2 inhibitor.
Carcinogenesis 2005;26(6):1109-16.
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2005: Zeng Yu; Yokohira Masanao; Takeuchi Hijiri; Saoo Kousuke; Yamakawa Keiko; Matsuda Yoko; Hosokawa Kyoko; Li Jia-Qing; Ikeda Mico; Imaida Katsumi
Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats.
Cancer letters 2005;222(2):145-51.
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2005: Fukushima Shoji; Wanibuchi Hideki; Morimura Keiichirou; Nakae Dai; Tsuda Hiroyuki; Imaida Katsumi; Shirai Tomoyuki; Tatematsu Masae; Tsukamoto Tetsuya; Hirose Masao; Furukawa Fumio
Lack of potential of low dose N-nitrosodimethylamine to induce preneoplastic lesions, glutathione S-transferase placental form-positive foci, in rat liver.
Cancer letters 2005;222(1):11-5.
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2005: Ichihara Toshio; Miyashita Kayoko; Kawabe Mayumi; Imaida Katsumi; Asamoto Makoto; Ogiso Tadashi; Tamano Seiko; Hirose Masao; Shirai Tomoyuki
Lack of combination hepatocarcinogenicity of harman, norharman and amitrole when given with NaNO2 in the rat.
The Journal of toxicological sciences 2005;30(1):1-6.
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2005: Shirai Tomoyuki; Kawabe Mayumi; Ichihara Toshio; Fujiwara Osamu; Taki Masao; Watanabe So-ichi; Wake Kanako; Yamanaka Yukio; Imaida Katsumi; Asamoto Makoto; Tamano Seiko
Chronic exposure to a 1.439 GHz electromagnetic field used for cellular phones does not promote N-ethylnitrosourea induced central nervous system tumors in F344 rats.
Bioelectromagnetics 2005;26(1):59-68.
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2005: Matsuda Yoko; Saoo Kousuke; Hosokawa Kyoko; Yamakawa Keiko; Yokohira Masanao; Zeng Yu; Takeuchi Hijiri; Iwai Junko; Shirai Takatoshi; Obika Kaoru; Imaida Katsumi
Epithelioid malignant peripheral nerve sheath tumor. Report of a case with inflammatory infiltration.
Pathology, research and practice 2005;201(4):355-60.
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2004: Inaguma Shingo; Takahashi Satoru; Imaida Katsumi; Suzuki Shugo; Shirai Tomoyuki
p-Nonylphenol pretreatment during the late neonatal period has no effect on 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in male F344 rats.
Cancer letters 2004;212(2):159-66.
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2004: Li Jia-Qing; Wu Fei; Masaki Tsutomu; Kubo Akihito; Fujita Jiro; Dixon Dan A; Beauchamp R Daniel; Ishida Toshihiko; Kuriyama Shigeki; Imaida Katsumi
Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors.
International journal of oncology 2004;25(1):87-95.
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2004: Fukushima S; Wanibuchi H; Morimura K; Iwai S; Nakae D; Kishida H; Tsuda H; Uehara N; Imaida K; Shirai T; Tatematsu M; Tsukamoto T; Hirose M; Furukawa F
Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b]pyridine.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(1):109-14.
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2004: Orita Shinichiro; Hirose Masao; Takahashi Satoru; Imaida Katsumi; Ito Nobuyuki; Shudo Koichi; Ohigashi Hajime; Murakami Akira; Shirai Tomoyuki
Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats.
Toxicologic pathology 2004;32(2):250-7.
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2003: Li Jia-Qing; Wu Fei; Usuki Hisashi; Kubo Akihito; Masaki Tsutomu; Fujita Jiro; Bandoh Shuji; Saoo Kousuke; Takeuchi Hijiri; Kuriyama Shigeki; Ishida Toshihiko; Imaida Katsumi
Loss of p57KIP2 is associated with colorectal carcinogenesis.
International journal of oncology 2003;23(6):1537-43.
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2003: Takeuchi Hijiri; Saoo Kousuke; Yokohira Masanao; Ikeda Mico; Maeta Hajime; Miyazaki Masafumi; Yamazaki Hiroshi; Kamataki Tetsuya; Imaida Katsumi
Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
Cancer research 2003;63(22):7581-3.
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2003: Li Jia-Qing; Kubo Akihito; Wu Fei; Usuki Hisashi; Fujita Jiro; Bandoh Shuji; Masaki Tsutomu; Saoo Kousuke; Takeuchi Hijiri; Kobayashi Shoji; Imaida Katsumi; Maeta Hajime; Ishida Toshihiko; Kuriyama Shigeki
Cyclin B1, unlike cyclin G1, increases significantly during colorectal carcinogenesis and during later metastasis to lymph nodes.
International journal of oncology 2003;22(5):1101-10.
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2003: Fukushima Shoji; Wanibuchi Hideki; Morimura Keiichirou; Wei Min; Nakae Dai; Konishi Yoichi; Tsuda Hiroyuki; Takasuka Nobuo; Imaida Katsumi; Shirai Tomoyuki; Tatematsu Masae; Tsukamoto Tetsuya; Hirose Masao; Furukawa Fumio
Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Cancer letters 2003;191(1):35-40.
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2003: Tsuda Hiroyuki; Fukushima Shoji; Wanibuchi Hideki; Morimura Keiichirou; Nakae Dai; Imaida Katsumi; Tatematsu Masae; Hirose Masao; Wakabayashi Keiji; Moore Malcolm A
Value of GST-P positive preneoplastic hepatic foci in dose-response studies of hepatocarcinogenesis: evidence for practical thresholds with both genotoxic and nongenotoxic carcinogens. A review of recent work.
Toxicologic pathology 2003;31(1):80-6.
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2002: Shirai Tomoyuki; Asamoto Makoto; Takahashi Satoru; Imaida Katsumi
Diet and prostate cancer.
Toxicology 2002;181-182():89-94.
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2002: Fukushima Shoji; Wanibuchi Hideki; Morimura Keiichirou; Wei Min; Nakae Dai; Konishi Yoichi; Tsuda Hiroyuki; Uehara Nobuaki; Imaida Katsumi; Shirai Tomoyuki; Tatematsu Masae; Tsukamoto Tetsuya; Hirose Masao; Furukawa Fumio; Wakabayashi Keiji; Totsuka Yukari
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine.
Japanese journal of cancer research : Gann 2002;93(10):1076-82.
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2002: Li Jia-Qing; Miki Hiroshi; Wu Fei; Saoo Kousuke; Nishioka Mikio; Ohmori Masaki; Imaida Katsumi
Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms.
Human pathology 2002;33(10):1006-15.
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2002: Shirai T; Kato K; Futakuchi M; Takahashi S; Suzuki S; Imaida K; Asamoto M
Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas.
Mutation research 2002;506-507():129-36.
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2002: Takahashi Satoru; Inaguma Shingo; Cho Young-Man; Imaida Katsumi; Wang Jianqing; Fujiwara Osamu; Shirai Tomoyuki
Lack of mutation induction with exposure to 1.5 GHz electromagnetic near fields used for cellular phones in brains of Big Blue mice.
Cancer research 2002;62(7):1956-60.
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2002: Hagiwara Akihiro; Yoshino Hiroko; Ichihara Toshio; Kawabe Mayumi; Tamano Seiko; Aoki Hiromitsu; Koda Takatoshi; Nakamura Mikio; Imaida Katsumi; Ito Nobuyuki; Shirai Tomoyuki
Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine.
The Journal of toxicological sciences 2002;27(1):57-68.
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2002: Futakuchi Mitsuru; Hirose Masao; Imaida Katsumi; Takahashi Satoru; Ogawa Kumiko; Asamoto Makoto; Miki Tokutaro; Shirai Tomoyuki
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats.
Carcinogenesis 2002;23(2):283-7.
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2001: Imaida K; Kuzutani K; Wang J; Fujiwara O; Ogiso T; Kato K; Shirai T
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Carcinogenesis 2001;22(11):1837-41.
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2001: Mori T; Imaida K; Tamano S; Sano M; Takahashi S; Asamoto M; Takeshita M; Ueda H; Shirai T
Beef tallow, but not perilla or corn oil, promotion of rat prostate and intestinal carcinogenesis by 3,2'-dimethyl-4-aminobiphenyl.
Japanese journal of cancer research : Gann 2001;92(10):1026-33.
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2001: Hagiwara A; Miyashita K; Nakanishi T; Sano M; Tamano S; Kadota T; Koda T; Nakamura M; Imaida K; Ito N; Shirai T
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Cancer letters 2001;171(1):17-25.
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2001: Imaida K; Sano M; Tamano S; Asamoto M; Ogawa K; Futakuchi M; Shirai T
Organ dependent enhancement of rat 3,2'-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): positive effects on the intestine but not the prostate.
Carcinogenesis 2001;22(8):1295-9.
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2001: Asamoto M; Hokaiwado N; Cho Y M; Takahashi S; Ikeda Y; Imaida K; Shirai T
Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent.
Cancer research 2001;61(12):4693-700.
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2001: Ogawa K; Nakanishi H; Takeshita F; Futakuchi M; Asamoto M; Imaida K; Tatematsu M; Shirai T
Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice.
International journal of cancer. Journal international du cancer 2001;91(6):797-802.
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2001: Imaida K; Tamano S; Kato K; Ikeda Y; Asamoto M; Takahashi S; Nir Z; Murakoshi M; Nishino H; Shirai T
Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis.
Carcinogenesis 2001;22(3):467-72.
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2001: Hokaiwado N; Asamoto M; Cho Y M; Imaida K; Shirai T
Frequent c-Ha-ras gene mutations in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Cancer letters 2001;163(2):187-90.
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2001: Ogawa K; Hirose M; Sugiura S; Cui L; Imaida K; Ogiso T; Shirai T
Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis.
Nutrition and cancer 2001;40(2):134-9.
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2000: Imaida K; Shirai T
[Endocrine disrupting chemicals and carcinogenesis--breast, testis and prostate cancer]
Nippon rinsho. Japanese journal of clinical medicine 2000;58(12):2527-32.
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2000: Takahashi S; Ikeda Y; Orita S; Sakakibara M; Kimoto N; Suzuki S; Imaida K; Shirai T
Enhancing effects of 2-amino-4,5-diphenylthiazole-induced polycystic kidneys on renal carcinogenesis in rats treated with dimethylnitrosamine.
Toxicology and applied pharmacology 2000;167(1):12-7.
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2000: Imaida K; Hagiwara A; Yoshino H; Tamano S; Sano M; Futakuchi M; Ogawa K; Asamoto M; Shirai T
Inhibitory effects of low doses of melatonin on induction of preneoplastic liver lesions in a medium-term liver bioassay in F344 rats: relation to the influence of electromagnetic near field exposure.
Cancer letters 2000;155(1):105-14.
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2000: Shirai T; Takahashi S; Cui L; Futakuchi M; Kato K; Tamano S; Imaida K
Experimental prostate carcinogenesis - rodent models.
Mutation research 2000;462(2-3):219-26.
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2000: Ito N; Imaida K; Asamoto M; Shirai T
Early detection of carcinogenic substances and modifiers in rats.
Mutation research 2000;462(2-3):209-17.
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2000: Imaida K; Ogawa K; Takahashi S; Ito T; Yamaguchi T; Totsuka Y; Wakabayashi K; Tanaka K; Ito N; Shirai T
Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl-imidazo [4,5-b] pyridine (PhIP).
Cancer letters 2000;150(1):63-9.
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2000: Yaono M; Tamano S; Mori T; Kato K; Imaida K; Asamoto M; Shirai T
Lobe specific effects of testosterone and estrogen on 3,2'-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis.
Cancer letters 2000;150(1):33-40.
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1999: Ikeda Y; Takahashi S; Kimura J; Cho Y M; Imaida K; Shirai S; Shirai T
Anophthalmia in litters of female rats treated with the food-derived carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Toxicologic pathology 1999;27(6):628-31.
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1999: Sano M; Hagiwara A; Tamano S; Hasegawa R; Imaida K; Ito N; Shirai T
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
The Journal of toxicological sciences 1999;24(3):177-86.
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1999: Moore M A; Tsuda H; Tamano S; Hagiwara A; Imaida K; Shirai T; Ito N
Marriage of a medium-term liver model to surrogate markers--a practical approach for risk and benefit assessment.
Toxicologic pathology 1999;27(2):237-42.
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1998: Ito N; Imaida K; Hirose M; Shirai T
Medium-term bioassays for carcinogenicity of chemical mixtures.
Environmental health perspectives 1998;106 Suppl 6():1331-6.
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1998: Imaida K; Taki M; Watanabe S; Kamimura Y; Ito T; Yamaguchi T; Ito N; Shirai T
The 1.5 GHz electromagnetic near-field used for cellular phones does not promote rat liver carcinogenesis in a medium-term liver bioassay.
Japanese journal of cancer research : Gann 1998;89(10):995-1002.
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1998: Ito N; Imaida K; Tamano S; Hagiwara A; Shirai T
Medium-term bioassays as alternative carcinogenicity test.
The Journal of toxicological sciences 1998;23 Suppl 2():103-6.
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1998: Imaida K; Taki M; Yamaguchi T; Ito T; Watanabe S; Wake K; Aimoto A; Kamimura Y; Ito N; Shirai T
Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay.
Carcinogenesis 1998;19(2):311-4.
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1998: Cui L; Mori T; Takahashi S; Imaida K; Akagi K; Yada H; Yaono M; Shirai T
Slight promotion effects of intermittent administration of testosterone propionate and/or diethylstilbestrol on 3,2'-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis.
Cancer letters 1998;122(1-2):195-9.
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1997: Ito N; Hasegawa R; Imaida K; Tamano S; Hagiwara A; Hirose M; Shirai T
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Mutation research 1997;376(1-2):107-14.
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1997: Imaida K; Hasegawa R; Kato T; Futakuchi M; Takahashi S; Ogawa K; Asamoto M; Yamamoto T; Suzuki K; Inagaki T; Shinagawa N; Shirai T
Clinicopathological analysis on cancers of autopsy cases in a geriatric hospital.
Pathology international 1997;47(5):293-300.
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1997: Shirai T; Sano M; Tamano S; Takahashi S; Hirose M; Futakuchi M; Hasegawa R; Imaida K; Matsumoto K; Wakabayashi K; Sugimura T; Ito N
The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.
Cancer research 1997;57(2):195-8.
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1996: Imaida K; Fukushima S
Initiation-promotion model for assessment of carcinogenicity: medium-term liver bioassay in rats for rapid detection of carcinogenic agents.
The Journal of toxicological sciences 1996;21(5):483-7.
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1996: Ito N; Hagiwara A; Tamano S; Futacuchi M; Imaida K; Shirai T
Effects of pesticide mixtures at the acceptable daily intake levels on rat carcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(11-12):1091-6.
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1996: Hasegawa R; Yoshimura I; Imaida K; Ito N; Shirai T
Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat.
Japanese journal of cancer research : Gann 1996;87(11):1125-33.
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1996: Imaida K; Hagiwara A; Yada H; Masui T; Hasegawa R; Hirose M; Sugimura T; Ito N; Shirai T
Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine.
Japanese journal of cancer research : Gann 1996;87(11):1116-20.
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1996: Mori T; Cui L; Kato K; Takahashi S; Imaida K; Iwasaki S; Ito N; Shirai T
Direct effects of testosterone, dihydrotestosterone and estrogen on 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in castrated F344 rats.
Japanese journal of cancer research : Gann 1996;87(6):570-4.
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1996: Imaida K
Delayed toxicity associated with morphological changes in animal experiments.
The Journal of toxicological sciences 1996;21(1):97-103.
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1996: Ito N; Hasegawa R; Imaida K; Hirose M; Shirai T
Medium-term liver and multi-organ carcinogenesis bioassays for carcinogens and chemopreventive agents.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(2-3):113-9.
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1996: Ogawa K; Imaida K; Masui T; Kawabe M; Hasegawa R; Kato K; Ito N; Shirai T
Chemically induced lung and forestomach neoplasias in transgenic mice carry mutant forms of the human c-Ha-ras transgene.
Carcinogenesis 1996;17(2):341-5.
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1995: Ito N; Hagiwara A; Tamano S; Hasegawa R; Imaida K; Hirose M; Shirai T
Lack of carcinogenicity of pesticide mixtures administered in the diet at acceptable daily intake (ADI) dose levels in rats.
Toxicology letters 1995;82-83():513-20.
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1995: Ito N; Hasegawa R; Imaida K; Hirose M; Asamoto M; Shirai T
Concepts in multistage carcinogenesis.
Critical reviews in oncology/hematology 1995;21(1-3):105-133.
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1995: Shibata M; Hasegawa R; Imaida K; Hagiwara A; Ogawa K; Hirose M; Ito N; Shirai T
Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model.
Cancer research 1995;55(21):4870-4.
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1995: Shirai T; Tamano S; Sano M; Imaida K; Hagiwara A; Futakuchi M; Takahashi S; Hirose M
Site-specific effects of testosterone propionate on the prostate of rat pretreated with 3,2'-dimethyl-4-aminobiphenyl: dose-dependent induction of invasive carcinomas.
Japanese journal of cancer research : Gann 1995;86(7):645-8.
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1995: Masui T; Shirai T; Imaida K; Hirose M; Futakuchi M; Tatematsu M; Ito N
Ki-ras mutations with frequent normal allele loss versus absence of p53 mutations in rat prostate and seminal vesicle carcinomas induced with 3,2'-dimethyl-4-aminobiphenyl.
Molecular carcinogenesis 1995;13(1):21-6.
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1995: Shirai T; Shibata M; Takahashi S; Tagawa Y; Imaida K; Hirose M
Differences in cell proliferation and apoptosis between reversible and irreversible mucosal lesions associated with uracil-induced urolithiasis in N-butyl-N-(4-hydroxybutyl)nitrosamine-pretreated.
Carcinogenesis 1995;16(3):501-5.
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1995: Tanaka H; Hirose M; Hagiwara A; Imaida K; Shirai T; Ito N
Rat strain differences in catechol carcinogenicity to the stomach.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(2):93-8.
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1995: Ito N; Hasegawa R; Imaida K; Kurata Y; Hagiwara A; Shirai T
Effect of ingestion of 20 pesticides in combination at acceptable daily intake levels on rat liver carcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(2):159-63.
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1995: Hasegawa R; Ogiso T; Imaida K; Shirai T; Ito N
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(1):15-20.
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1995: Ito N; Hasegawa R; Asakawa E; Hirose M; Imaida K; Hagiwara A
Enhancement of rat liver cell foci development by combined treatment with heterocyclic amines at low doses.
Princess Takamatsu symposia 1995;23():251-9.
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1994: Hagiwara A; Tanaka H; Tamano S; Imaida K; Takahashi S; Fukushima S
Inhibiting effects of diethylmaleate or NH4Cl on NaHCO3, but not butylated hydroxyanisole, promotion of urinary bladder carcinogenesis in male F344 rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
The Journal of toxicological sciences 1994;19(4):189-95.
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1994: Asamoto M; Takahashi S; Imaida K; Shirai T; Fukushima S
Increased gap junctional intercellular communication capacity and connexin 43 and 26 expression in rat bladder carcinogenesis.
Carcinogenesis 1994;15(10):2163-6.
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1994: Shirai T; Sano M; Imaida K; Takahashi S; Mori T; Ito N
Duration dependent induction of invasive prostatic carcinomas with pharmacological dose of testosterone propionate in rats pretreated with 3,2'-dimethyl-4-aminobiphenyl and development of androgen-independent carcinomas after castration.
Cancer letters 1994;83(1-2):111-6.
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1994: Shirai T; Imaida K; Masui T; Iwasaki S; Mori T; Kato T; Ito N
Effects of testosterone, dihydrotestosterone and estrogen on 3,2'-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis.
International journal of cancer. Journal international du cancer 1994;57(2):224-8.
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1994: Shioya S; Nagami-Oguihara R; Oguihara S; Kimura T; Imaida K; Fukushima S
Roles of bladder distension, urinary pH and urinary sodium ion concentration in cell proliferation of urinary bladder epithelium in rats ingesting sodium salts.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(2):165-71.
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1994: Ito N; Hasegawa R; Imaida K; Takahashi S; Shirai T
Medium-term rat liver bioassay for rapid detection of carcinogens and modifiers of hepatocarcinogenesis.
Drug metabolism reviews 1994;26(1-2):431-42.
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1993: Kato T; Imaida K; Ogawa K; Hesegawa R; Shirai T; Tatematsu M
Three-dimensional analysis of glutathione S-transferase placental form-positive lesion development in early stages of rat hepatocarcinogenesis.
Japanese journal of cancer research : Gann 1993;84(12):1252-7.
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1993: Hasegawa R; Sano M; Tamano S; Imaida K; Shirai T; Nagao M; Sugimura T; Ito N
Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats.
Carcinogenesis 1993;14(12):2553-7.
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1993: Shibata M A; Sano M; Shirai T; Imaida K; Fukushima S
Epithelia hyperplasia in the renal papilla and pelvis but not the urinary bladder of male F344 rats associated with dietary sodium phosphates after uracil exposure.
Toxicology and applied pharmacology 1993;121(2):303-12.
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1993: Toyoda K; Imaida K; Shirai T; Imazawa T; Takahashi M
Relationship between bisacodyl-induced urolithiasis and rat urinary bladder tumorigenesis.
Journal of toxicology and environmental health 1993;39(1):59-78.
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1993: Hagiwara A; Tanaka H; Imaida K; Tamano S; Fukushima S; Ito N
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats.
Japanese journal of cancer research : Gann 1993;84(3):237-45.
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1993: Shirai T; Imaida K; Iwasaki S; Mori T; Tada M; Ito N
Sequential observation of rat prostate lesion development induced by 3,2'-dimethyl-4-aminobiphenyl and testosterone.
Japanese journal of cancer research : Gann 1993;84(1):20-5.
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1993: Hagiwara A; Tiwawech D; Imaida K; Tamano S; Shibata M A; Fukushima S; Ito N
Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay.
Teratogenesis, carcinogenesis, and mutagenesis 1993;13(6):277-87.
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1992: Ito N; Hasegawa R; Imaida K; Masui T; Takahashi S; Shirai T
Pathological markers for non-genotoxic agent-associated carcinogenesis.
Toxicology letters 1992;64-65 Spec No():613-20.
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1992: Tatematsu M; Ogawa K; Hoshiya T; Shichino Y; Kato T; Imaida K; Ito N
Induction of adenocarcinomas in the glandular stomach of BALB/c mice treated with N-methyl-N-nitrosourea.
Japanese journal of cancer research : Gann 1992;83(9):915-8.
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1992: Shirai T; Iwasaki S; Naito H; Masui T; Kato T; Imaida K
Dose dependence of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis.
Japanese journal of cancer research : Gann 1992;83(7):695-8.
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1992: Asamoto M; Imaida K; Hasegawa R; Hotta K; Fukushima S
Change of membrane potential in rat urinary bladder epithelium treated with sodium L-ascorbate.
Cancer letters 1992;63(1):1-5.
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1992: Ito N; Imaida K
Strategy of research for cancer--chemoprevention.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(2):79-95.
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1992: Shirai T; Yamamoto A; Imaida K; Tamano S; Mori T; Hasegawa R
Lack of synergism among DMAB, BOP, and MNU in induction of carcinomas of the rat ventral prostate.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(2):71-7.
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1992: Yoshida Y; Hasegawa R; Takaba K; Imaida K; Ito N
N-nitrosoheptamethyleneimine-induced pulmonary and esophageal carcinogenesis and effects of concomitant treatment with bleomycin in rats.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(5):197-201.
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1991: Hasegawa R; Takahashi S; Imaida K; Yamaguchi S; Shirai T; Ito N
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine.
Japanese journal of cancer research : Gann 1991;82(3):293-7.
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1990: Imaida K; Hirose M; Yamaguchi S; Takahashi S; Ito N
Effects of naturally occurring antioxidants on combined 1,2-dimethylhydrazine- and 1-methyl-1-nitrosourea-initiated carcinogenesis in F344 male rats.
Cancer letters 1990;55(1):53-9.
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1989: Hasegawa R; Mutai M; Imaida K; Tsuda H; Yamaguchi S; Ito N
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver.
Japanese journal of cancer research : Gann 1989;80(10):945-51.
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1989: Imaida K; Tatematsu M; Kato T; Tsuda H; Ito N
Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction.
Japanese journal of cancer research : Gann 1989;80(4):326-30.
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1989: Ito N; Imaida K; Hasegawa R; Tsuda H
Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis.
Critical reviews in toxicology 1989;19(4):385-415.
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1988: Imaida K; Fukushima S; Inoue K; Masui T; Hirose M; Ito N
Modifying effects of concomitant treatment with butylated hydroxyanisole or butylated hydroxytoluene on N,N-dibutylnitrosamine-induced liver, forestomach and urinary bladder carcinogenesis in F344 male rats.
Cancer letters 1988;43(3):167-72.
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1988: Fukushima S; Imaida K; Shibata M A; Tamano S; Kurata Y; Shirai T
L-ascorbic acid amplification of second-stage bladder carcinogenesis promotion by NaHCO3.
Cancer research 1988;48(22):6317-20.
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1988: Inoue T; Imaida K; Suzuki E; Okada M; Fukushima S
Combined effects of L-ascorbic acid, citric acid or their sodium salts on tumor induction by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-ethyl-N-(4-hydroxybutyl)nitrosamine in the rat urinary bladder.
Cancer letters 1988;40(3):265-73.
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1988: Ito N; Imaida K; de Camargo J L; Takahashi S; Asamoto M; Tsuda H
A new medium-term bioassay system for detection of environmental carcinogens using diethylnitrosamine-initiated rat liver followed by D-galactosamine treatment and partial hepatectomy.
Japanese journal of cancer research : Gann 1988;79(5):573-5.
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1988: Shirai T; Masuda A; Imaida K; Ogiso T; Ito N
Effects of phenobarbital and carbazole on carcinogenesis of the lung, thyroid, kidney, and bladder of rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.
Japanese journal of cancer research : Gann 1988;79(4):460-5.
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1988: Nakanowatari J; Fukushima S; Imaida K; Ito N; Nagase S
Strain differences in N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis in rats.
Japanese journal of cancer research : Gann 1988;79(4):453-9.
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1988: Ito N; Imaida K; Tsuda H; Shibata M; Aoki T; de Camargo J L; Fukushima S
Wide-spectrum initiation models: possible applications to medium-term multiple organ bioassays for carcinogenesis modifiers.
Japanese journal of cancer research : Gann 1988;79(4):413-7.
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1988: Masui T; Shirai T; Imaida K; Uwagawa S; Fukushima S
Effects of urinary crystals induced by acetazolamide, uracil, and diethylene glycol on urinary bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated rats.
Toxicology letters 1988;40(2):119-26.
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1987: Shirai T; Tagawa Y; Fukushima S; Imaida K; Ito N
Strong promoting activity of reversible uracil-induced urolithiasis on urinary bladder carcinogenesis in rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Cancer research 1987;47(24 Pt 1):6726-30.
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1987: Tsuda H; Masui T; Ikawa E; Imaida K; Ito N
Compared promoting potential of D-galactosamine, carbon tetrachloride and partial hepatectomy in rapid induction of preneoplastic liver lesions in the rat.
Cancer letters 1987;37(2):163-71.
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