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Taiji Imoto

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Living Beings

Chickens

Disorders

Protein Denaturation

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Physiology

Occupations

Thermodynamics

Objects

Egg White

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Co-Publications
Name
82
Ueda, Tadashi
20
Hashimoto, Yoshio
14
Ohkuri, Takatoshi
12
Abe, Yoshito
10
So, Takanori
8
Motoshima, Hiroyuki
7
Yoshida, Yuichiro
5
Monji, Akira
4
Obita, Takayuki
4
Tanaka, Yoshitsugu
4
Tsujihata, Yoshiyuki
4
Ninomiya, Yuzo
4
Nishimura, Y
4
Katsukawa, Hideo
4
Koga, Tetsuya

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Publications

TOP 3
Goto Takashi; Ohkuri Takatoshi; Shioi Seijiro; Abe Yoshito; Imoto Taiji; Ueda Tadashi
Crystal structures of K33 mutant hen lysozymes with enhanced activities.
Ohkuri Takatoshi; Takeda Chika; Yoshida Yuichiro; Izuhara Kenji; Imoto Taiji; Ueda Tadashi
Expression of human IL-13 receptor alpha2 extracellular domain in Pichia pastoris.
Kameoka Daisuke; Masuzaki Etsuro; Ueda Tadashi; Imoto Taiji
Effect of buffer species on the unfolding and the aggregation of humanized IgG.

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All Publications

2008: Goto Takashi; Ohkuri Takatoshi; Shioi Seijiro; Abe Yoshito; Imoto Taiji; Ueda Tadashi
Crystal structures of K33 mutant hen lysozymes with enhanced activities.
Journal of biochemistry 2008;144(5):619-23.
2007: Ohkuri Takatoshi; Takeda Chika; Yoshida Yuichiro; Izuhara Kenji; Imoto Taiji; Ueda Tadashi
Expression of human IL-13 receptor alpha2 extracellular domain in Pichia pastoris.
Protein expression and purification 2007;56(1):48-53.
2007: Kameoka Daisuke; Masuzaki Etsuro; Ueda Tadashi; Imoto Taiji
Effect of buffer species on the unfolding and the aggregation of humanized IgG.
Journal of biochemistry 2007;142(3):383-91.
2007: Goto Takashi; Abe Yoshito; Kakuta Yoshimitsu; Takeshita Kohei; Imoto Taiji; Ueda Tadashi
Crystal structure of Tapes japonica Lysozyme with substrate analogue: structural basis of the catalytic mechanism and manifestation of its chitinase activity accompanied by quaternary structural change.
The Journal of biological chemistry 2007;282(37):27459-67.
2007: Mishima Tomonori; Ohkuri Takatoshi; Imoto Taiji; Ueda Tadashi
Analyses of native disulfide bond formations in the early stage of the folding process in mutant lysozymes where the long-range interactions in the denatured state were modulated.
Bioscience, biotechnology, and biochemistry 2007;71(8):2072-4.
2007: Yoshida Yuichiro; Ohkuri Takatoshi; Takeda Chika; Kuroki Ryota; Izuhara Kenji; Imoto Taiji; Ueda Tadashi
Analysis of internal motions of interleukin-13 variant associated with severe bronchial asthma using (15)N NMR relaxation measurements.
Biochemical and biophysical research communications 2007;358(1):292-7.
2007: Mishima Tomonori; Ohkuri Takatoshi; Monji Akira; Imoto Taiji; Ueda Tadashi
A particular hydrophobic cluster in the residual structure of reduced lysozyme drastically affects the amyloid fibrils formation.
Biochemical and biophysical research communications 2007;356(3):769-72.
2006: Mishima Tomonori; Ohkuri Takatoshi; Monji Akira; Imoto Taiji; Ueda Tadashi
Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated.
Protein science : a publication of the Protein Society 2006;15(10):2448-52.
2006: Yoshida Yuichiro; Tanaka Masakazu; Ohkuri Takatoshi; Tanaka Yoshitsugu; Imoto Taiji; Ueda Tadashi
Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements.
Journal of biochemistry 2006;140(1):43-8.
2006: Yamada Ayako; Nakamura Yuki; Sugita Daigo; Shirosaki Shinya; Ohkuri Tadahiro; Katsukawa Hideo; Nonaka Kazuaki; Imoto Toshiaki; Ninomiya Yuzo
Induction of salivary kallikreins by the diet containing a sweet-suppressive peptide, gurmarin, in the rat.
Biochemical and biophysical research communications 2006;346(2):386-92.
2005: Ohkuri Takatoshi; Imoto Taiji; Ueda Tadashi
Effect of W62G mutation of hen lysozyme on the folding in vivo.
Biochemical and biophysical research communications 2005;338(2):820-4.
2005: Ohkuri Takatoshi; Imoto Taiji; Ueda Tadashi
Characterization of refolded hen lysozyme variant lacking two outside disulfide bonds.
Bioscience, biotechnology, and biochemistry 2005;69(6):1206-8.
2005: Yoshida Y; Ohkuri T; Kino S; Ueda T; Imoto T
Elucidation of the relationship between enzyme activity and internal motion using a lysozyme stabilized by cavity-filling mutations.
Cellular and molecular life sciences : CMLS 2005;62(9):1047-55.
2005: Ohkuri Takatoshi; Shioi Seijiro; Imoto Taiji; Ueda Tadashi
Effect of the structure of the denatured state of lysozyme on the aggregation reaction at the early stages of folding from the reduced form.
Journal of molecular biology 2005;347(1):159-68.
2005: Shigemura Noriatsu; Yasumatsu Keiko; Yoshida Ryusuke; Sako Noritaka; Katsukawa Hideo; Nakashima Kiyohito; Imoto Toshiaki; Ninomiya Yuzo
The role of the dpa locus in mice.
Chemical senses 2005;30 Suppl 1():i84-5.
2005: Ueno K; Ueda T; Sakai K; Abe Y; Hamasaki N; Okamoto M; Imoto T
Evidence for a novel racemization process of an asparaginyl residue in mouse lysozyme under physiological conditions.
Cellular and molecular life sciences : CMLS 2005;62(2):199-205.
2004: Shioi Seijiro; Imoto Taiji; Ueda Tadashi
Analysis of the early stage of the folding process of reduced lysozyme using all lysozyme variants containing a pair of cysteines.
Biochemistry 2004;43(18):5488-93.
2003: Yoshida Y; Obita T; Kokusho Y; Ohmura T; Katayama T; Ueda T; Imoto T
Identification of the region in Escherichia coli DnaA protein required for specific recognition of the DnaA box.
Cellular and molecular life sciences : CMLS 2003;60(9):1998-2008.
2003: Takeshita K; Hashimoto Y; Ueda T; Imoto T
A small chimerically bifunctional monomeric protein: Tapes japonica lysozyme.
Cellular and molecular life sciences : CMLS 2003;60(9):1944-51.
2003: Kameoka Daisuke; Ueda Tadashi; Imoto Taiji
A method for the detection of asparagine deamidation and aspartate isomerization of proteins by MALDI/TOF-mass spectrometry using endoproteinase Asp-N.
Journal of biochemistry 2003;134(1):129-35.
2003: Imoto Taiji
[Enjoying research on lysozymes for 42 years]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2003;123(6):377-86.
2003: Obita T; Ueda T; Imoto T
Solution structure and activity of mouse lysozyme M.
Cellular and molecular life sciences : CMLS 2003;60(1):176-84.
2002: Tsujihata Yoshiyuki; Mizukami Yousuke; Ueda Tadashi; So Takanori; Imoto Taiji
B-cell repertoire specific for an unfolded self-determinant of mouse lysozyme escape tolerance and dominantly participate in the autoantibody response.
Immunology 2002;107(4):394-402.
2002: Obita Takayuki; Iwura Takafumi; Su'etsugu Masayuki; Yoshida Yoichiro; Tanaka Yoshitsugu; Katayama Tsutomu; Ueda Tadashi; Imoto Taiji
Determination of the secondary structure in solution of the Escherichia coli DnaA DNA-binding domain.
Biochemical and biophysical research communications 2002;299(1):42-8.
2002: Kunichika Kaori; Hashimoto Yoshio; Imoto Taiji
Robustness of hen lysozyme monitored by random mutations.
Protein engineering 2002;15(10):805-9.
2002: Masumoto Kiyonari; Ueda Tadashi; Nagata Makiko; Yamada Yuko; Yoshida Yuichiro; Hashimoto Yoshio; Imoto Taiji
Effects of stereochemistry of sugars on protein stabilities.
Protein and peptide letters 2002;9(5):435-9.
2002: Imoto Taiji
[Foundation of the bases for protein research and its application to the pharmaceutical science field]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2002;122(8):537-46.
2002: Ohkuri Takatoshi; Ueda Tadashi; Yoshida Yuichiro; Abe Yoshito; Hamasaki Naotaka; Imoto Taiji
A metal binding in the polypeptide chain improves the folding efficiency of a denatured and reduced protein.
Biopolymers 2002;64(2):106-14.
2002: Ohmura Tadahiro; Motoshima Hiroyuki; Ueda Tadashi; Imoto Taiji
Fluctuations in free or substrate-complexed lysozyme and a mutant of it detected on x-ray crystallography and comparison with those detected on NMR.
Journal of biochemistry 2002;131(5):701-4.
2002: Ueda Tadashi; Nagata Makiko; Monji Akira; Yoshida Ichiro; Tashiro Nobutada; Imoto Taiji
Effect of sucrose on formation of the beta-amyloid fibrils and D-aspartic acids in Abeta 1-42.
Biological & pharmaceutical bulletin 2002;25(3):375-8.
2002: Monji Akira; Utsumi Hideo; Ueda Tadashi; Imoto Taiji; Yoshida Ichiro; Hashioka Sadayuki; Tashiro Ken-ichiro; Tashiro Nobutada
Amyloid-beta-protein (A beta) (25-35)-associated free radical generation is strongly influenced by the aggregational state of the peptides.
Life sciences 2002;70(7):833-41.
2001: Ohkuri T; Ueda T; Tsurumaru M; Imoto T
Evidence for an initiation site for hen lysozyme folding from the reduced form using its dissected peptide fragments.
Protein engineering 2001;14(11):829-33.
2001: So T; Ito H; Hirata M; Ueda T; Imoto T
Contribution of conformational stability of hen lysozyme to induction of type 2 T-helper immune responses.
Immunology 2001;104(3):259-68.
2001: Hashimoto Y; Munemura O; Masumoto K; Ueda T; Imoto T
Thermostability of doubly glycosylated recombinant lysozyme.
Biological & pharmaceutical bulletin 2001;24(10):1102-7.
2001: Ueda T; Nagata M; Imoto T
Aggregation and chemical reaction in hen lysozyme caused by heating at pH 6 are depressed by osmolytes, sucrose and trehalose.
Journal of biochemistry 2001;130(4):491-6.
2001: Tsujihata Y; So T; Hashimoto Y; Ueda T; Imoto T
A single amino acid substitution in a self protein is sufficient to trigger autoantibody response.
Molecular immunology 2001;38(5):375-81.
2001: Ohmura T; Ueda T; Hashimoto Y; Imoto T
Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme.
Protein engineering 2001;14(6):421-5.
2001: Monji A; Utsumi H; Ueda T; Imoto T; Yoshida I; Hashioka S; Tashiro K; Tashiro N
The relationship between the aggregational state of the amyloid-beta peptides and free radical generation by the peptides.
Journal of neurochemistry 2001;77(6):1425-32.
2001: Ohmura T; Ueda T; Ootsuka K; Saito M; Imoto T
Stabilization of hen egg white lysozyme by a cavity-filling mutation.
Protein science : a publication of the Protein Society 2001;10(2):313-20.
2001: Imoto T
Effective protein folding in simple random search.
Biopolymers 2001;58(1):46-9.
2000: Obita T; Ueda T; Tanaka Y; Hashimoto Y; Imoto T
Assignment of 1H and 15N resonances of mouse lysozyme M.
Journal of biomolecular NMR 2000;18(4):361-2.
2000: Masumoto K; Ueda T; Motoshima H; Imoto T
Relationship between local structure and stability in hen egg white lysozyme mutant with alanine substituted for glycine.
Protein engineering 2000;13(10):691-5.
2000: Tsujihata Y; So T; Chijiiwa Y; Hashimoto Y; Hirata M; Ueda T; Imoto T
Mutant mouse lysozyme carrying a minimal T cell epitope of hen egg lysozyme evokes high autoantibody response.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3606-11.
2000: Mine S; Ueda T; Hashimoto Y; Imoto T
Analysis of the internal motion of free and ligand-bound human lysozyme by use of 15N NMR relaxation measurement: a comparison with those of hen lysozyme.
Protein science : a publication of the Protein Society 2000;9(9):1669-84.
2000: Hashimoto Y; Ikenaga T; Tanigawa K; Ueda T; Ezak I; Imoto T
Expression and characterization of human rheumatoid factor single-chain Fv.
Biological & pharmaceutical bulletin 2000;23(8):941-5.
2000: Ueda T; Masumoto K; Ishibashi R; So T; Imoto T
Remarkable thermal stability of doubly intramolecularly cross-linked hen lysozyme.
Protein engineering 2000;13(3):193-6.
1999: Hashimoto Y; Tanigawa K; Nakashima M; Sonoda K; Ueda T; Watanabe T; Imoto T
Construction of the single-chain Fv from 196-14 antibody toward ovarian cancer-associated antigen CA125.
Biological & pharmaceutical bulletin 1999;22(10):1068-72.
1999: Kunichika K; Hashimoto Y; Imoto T
Construction of a screening system for selecting lysozyme mutants unable to form a stable structure from random mutants.
Journal of biochemistry 1999;126(3):584-90.
1999: Katsukawa H; Imoto T; Ninomiya Y
Induction of salivary gurmarin-binding proteins in rats fed gymnema-containing diets.
Chemical senses 1999;24(4):387-92.
1999: So T; Ito H O; Tsujihata Y; Hirata M; Ueda T; Imoto T
The molecular weight ratio of monomethoxypolyethylene glycol (mPEG) to protein determines the immunotolerogenicity of mPEG proteins.
Protein engineering 1999;12(8):701-5.
1999: So T; Ito H O; Hirata M; Ueda T; Imoto T
Extended blood half-life of monomethoxypolyethylene glycol-conjugated hen lysozyme is a key parameter controlling immunological tolerogenicity.
Cellular and molecular life sciences : CMLS 1999;55(8-9):1187-94.
1999: Ito Y; Kuroki R; Ogata Y; Hashimoto Y; Sugimura K; Imoto T
Analysis of a catalytic pathway via a covalent adduct of D52E hen egg white mutant lysozyme by further mutation.
Protein engineering 1999;12(4):327-31.
1999: Mine S; Ueda T; Hashimoto Y; Tanaka Y; Imoto T
High-level expression of uniformly 15N-labeled hen lysozyme in Pichia pastoris and identification of the site in hen lysozyme where phosphate ion binds using NMR measurements.
FEBS letters 1999;448(1):33-7.
1999: Mine S; Tate S; Ueda T; Kainosho M; Imoto T
Analysis of the relationship between enzyme activity and its internal motion using nuclear magnetic resonance: 15N relaxation studies of wild-type and mutant lysozyme.
Journal of molecular biology 1999;286(5):1547-65.
1999: Fujita H; Saeki M; Yasunaga K; Ueda T; Imoto T; Himeno M
In vitro binding study of adaptor protein complex (AP-1) to lysosomal targeting motif (LI-motif).
Biochemical and biophysical research communications 1999;255(1):54-8.
1999: Ito Y; Yoshikawa A; Hotani T; Fukuda S; Sugimura K; Imoto T
Amino acid sequences of lysozymes newly purified from invertebrates imply wide distribution of a novel class in the lysozyme family.
European journal of biochemistry / FEBS 1999;259(1-2):456-61.
1998: Ueda T; Tsurumaru M; Imoto T
Kinetic measurement of the interaction between a lysozyme and its immobilized substrate analogue by means of surface plasmon resonance.
Journal of biochemistry 1998;124(4):712-6.
1998: Kawamura S; Abe Y; Ueda T; Masumoto K; Imoto T; Yamasaki N; Kimura M
Investigation of the structural basis for thermostability of DNA-binding protein HU from Bacillus stearothermophilus.
The Journal of biological chemistry 1998;273(32):19982-7.
1998: Ninomiya Y; Imoto T; Yatabe A; Kawamura S; Nakashima K; Katsukawa H
Enhanced responses of the chorda tympani nerve to nonsugar sweeteners in the diabetic db/db mouse.
The American journal of physiology 1998;274(5 Pt 2):R1324-30.
1998: Ito H O; So T; Hirata M; Koga T; Ueda T; Imoto T
Tolerogenic activity of polyethylene glycol-conjugated lysozyme distinct from that of the native counterpart.
Immunology 1998;93(2):200-7.
1998: Hashimoto Y; Koyabu N; Imoto T
Effects of signal sequences on the secretion of hen lysozyme by yeast: construction of four secretion cassette vectors.
Protein engineering 1998;11(2):75-7.
1998: Abe Y; Ueda T; Kawano K; Tanaka Y; Imoto T
Detection of a local interaction of hen lysozyme under highly denaturing conditions using chemically 13C-enriched methionine resonance.
Journal of biochemistry 1998;123(2):313-7.
1997: Abe Y; Ueda T; Imoto T
An improved method for preparing lysozyme with chemically 13C-enriched methionine residues using 2-aminothiophenol as a reagent of thiolysis.
Journal of biochemistry 1997;122(6):1153-9.
1997: Ueda T; Maeda Y; So T; Imoto T
Favourable interaction between heavy and light chains arrests the undesirable oligomerization of heavy chains in the refolding of denatured and reduced immunoglobulin G.
Cellular and molecular life sciences : CMLS 1997;53(11-12):929-34.
1997: So T; Ito H O; Koga T; Watanabe S; Ueda T; Imoto T
Depression of T-cell epitope generation by stabilizing hen lysozyme.
The Journal of biological chemistry 1997;272(51):32136-40.
1997: Mine S; Ueda T; Hashimoto Y; Imoto T
Improvement of the refolding yield and solubility of hen egg-white lysozyme by altering the Met residue attached to its N-terminus to Ser.
Protein engineering 1997;10(11):1333-8.
1997: Ohmura T; Ueda T; Motoshima H; Tamura T; Imoto T
Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography.
Journal of biochemistry 1997;122(3):512-7.
1997: Kuroki R; Ito Y; Kato Y; Imoto T
A covalent enzyme-substrate adduct in a mutant hen egg white lysozyme (D52E).
The Journal of biological chemistry 1997;272(32):19976-81.
1997: Motoshima H; Ueda T; Masumoto K; Hashimoto Y; Chijiiwa Y; Imoto T
Influence of mutations of the N-cap residue, Gly4, on stability and structure of hen lysozyme.
Journal of biochemistry 1997;122(1):25-31.
1997: Motoshima H; Mine S; Masumoto K; Abe Y; Iwashita H; Hashimoto Y; Chijiiwa Y; Ueda T; Imoto T
Analysis of the stabilization of hen lysozyme by helix macrodipole and charged side chain interaction.
Journal of biochemistry 1997;121(6):1076-81.
1997: Ito H O; So T; Ueda T; Imoto T; Koga T
Prevention of collagen-induced arthritis (CIA) by treatment with polyethylene glycol-conjugated type II collagen; distinct tolerogenic property of the conjugated collagen from the native one.
Clinical and experimental immunology 1997;108(2):213-9.
1997: Imoto T
Stabilization of protein.
Cellular and molecular life sciences : CMLS 1997;53(3):215-23.
1997: Ito H O; Ueda T; Hashimoto Y; Imoto T; Koga T
Quaternary structure-dependent idiotope and antigen binding of a monoclonal antibody specific for conformational epitope on type II collagen.
Cellular and molecular life sciences : CMLS 1997;53(1):51-60.
1996: Ueda T; Ohkuri T; Imoto T
Identification of the peptide region that folds native conformation in the early stage of the renaturation of reduced lysozyme.
Biochemical and biophysical research communications 1996;228(1):203-8.
1996: So T; Ueda T; Abe Y; Nakamata T; Imoto T
Situation of monomethoxypolyethylene glycol covalently attached to lysozyme.
Journal of biochemistry 1996;119(6):1086-93.
1996: Motoshima H; Ueda T; Imoto T
Analysis of the transition state in the unfolding of hen lysozyme by introduction of Gly-Pro and Pro-Gly sequences at the same site.
Journal of biochemistry 1996;119(6):1019-23.
1996: Maeda Y; Yamada H; Ueda T; Imoto T
Effect of additives on the renaturation of reduced lysozyme in the presence of 4 M urea.
Protein engineering 1996;9(5):461-5.
1996: Maeda Y; Ueda T; Imoto T
Effective renaturation of denatured and reduced immunoglobulin G in vitro without assistance of chaperone.
Protein engineering 1996;9(1):95-100.
1996: So T; Ito H O; Koga T; Ueda T; Imoto T
Reduced immunogenicity of monomethoxypolyethylene glycol-modified lysozyme for activation of T cells.
Immunology letters 1996;49(1-2):91-7.
1996: Ueda T; Iwashita H; Hashimoto Y; Imoto T
Stabilization of lysozyme by introducing N-glycosylation signal sequence.
Journal of biochemistry 1996;119(1):157-61.
1996: Hashimoto Y; Yamada K; Motoshima H; Omura T; Yamada H; Yasukochi T; Miki T; Ueda T; Imoto T
A mutation study of catalytic residue Asp 52 in hen egg lysozyme.
Journal of biochemistry 1996;119(1):145-50.
1995: Motoshima H; Ueda T; Hashimoto Y; Tsutsumi M; Imoto T
Correlation between the differences in the free energy change and conformational energy in the folded state of hen lysozymes with Gly-Pro and Pro-Gly sequences introduced to the same site.
Journal of biochemistry 1995;118(6):1138-44.
1995: Ueda T; Abe Y; Ohkuri T; Kawano K; Terada Y; Imoto T
Kinetically trapped structure in the renaturation of reduced oxindolealanine 62 lysozyme.
Biochemistry 1995;34(49):16178-85.
1995: Abe Y; Ueda T; Iwashita H; Hashimoto Y; Motoshima H; Tanaka Y; Imoto T
Effect of salt concentration on the pKa of acidic residues in lysozyme.
Journal of biochemistry 1995;118(5):946-52.
1995: Tomizawa H; Yamada H; Hashimoto Y; Imoto T
Stabilization of lysozyme against irreversible inactivation by alterations of the Asp-Gly sequences.
Protein engineering 1995;8(10):1023-8.
1995: Ito Y; Nakamura M; Hotani T; Imoto T
Insect lysozyme from house fly (Musca domestica) larvae: possible digestive function based on sequence and enzymatic properties.
Journal of biochemistry 1995;118(3):546-51.
1995: Tomizawa H; Yamada H; Wada K; Imoto T
Stabilization of lysozyme against irreversible inactivation by suppression of chemical reactions.
Journal of biochemistry 1995;117(3):635-40.
1995: Maeda Y; Koga H; Yamada H; Ueda T; Imoto T
Effective renaturation of reduced lysozyme by gentle removal of urea.
Protein engineering 1995;8(2):201-5.
1995: Tomizawa H; Yamada H; Tanigawa K; Imoto T
Effects of additives on irreversible inactivation of lysozyme at neutral pH and 100 degrees C.
Journal of biochemistry 1995;117(2):369-73.
1994: Ito Y; Hirashima M; Yamada H; Imoto T
Colonic lysozymes of rabbit (Japanese white): recent divergence and functional conversion.
Journal of biochemistry 1994;116(6):1346-53.
1994: Tomizawa H; Yamada H; Imoto T
The mechanism of irreversible inactivation of lysozyme at pH 4 and 100 degrees C.
Biochemistry 1994;33(44):13032-7.
1994: Maeda Y; Ueda T; Yamada H; Imoto T
The role of net charge on the renaturation of reduced lysozyme by the sulfhydryl-disulfide interchange reaction.
Protein engineering 1994;7(10):1249-54.
1994: Tomizawa H; Yamada H; Ueda T; Imoto T
Isolation and characterization of 101-succinimide lysozyme that possesses the cyclic imide at Asp101-Gly102.
Biochemistry 1994;33(29):8770-4.
1994: Imoto T; Ueda T; Tamura T; Isakari Y; Abe Y; Inoue M; Miki T; Kawano K; Yamada H
Lysozyme requires fluctuation of the active site for the manifestation of activity.
Protein engineering 1994;7(6):743-8.
1994: Ueda T; Nakashima A; Hashimoto Y; Miki T; Yamada H; Imoto T
Formation of alpha-helix 88-98 is essential in the establishment of higher-order structure from reduced lysozyme.
Journal of molecular biology 1994;235(4):1312-7.
1994: Abe Y; Ueda T; Imoto T
Reduction of disulfide bonds in proteins by 2-aminothiophenol under weakly acidic conditions.
Journal of biochemistry 1994;115(1):52-7.
1993: Kuribayashi M; Yamada H; Ohmori T; Yanai M; Imoto T
Endopeptidase activity of cathepsin C, dipeptidyl aminopeptidase I, from bovine spleen.
Journal of biochemistry 1993;113(4):441-9.
1993: Ito Y; Yamada H; Nakamura M; Yoshikawa A; Ueda T; Imoto T
The primary structures and properties of non-stomach lysozymes of sheep and cow, and implication for functional divergence of lysozyme.
European journal of biochemistry / FEBS 1993;213(2):649-58.
1993: Ueda T; Tamura T; Maeda Y; Hashimoto Y; Miki T; Yamada H; Imoto T
Stabilization of lysozyme by the introduction of Gly-Pro sequence.
Protein engineering 1993;6(2):183-7.
1993: Ueda T; Abe Y; Akasaki K; Yamaguchi Y; Tsuji H; Kawano K; Yamada H; Imoto T
Detection of subtle differences in the surface structure of lysozymes by use of an immobilized Fab fragment.
Journal of biochemistry 1993;113(2):174-9.
1992: Inoue M; Yamada H; Yasukochi T; Miki T; Horiuchi T; Imoto T
Left-sided substrate binding of lysozyme: evidence for the involvement of asparagine-46 in the initial binding of substrate to chicken lysozyme.
Biochemistry 1992;31(42):10322-30.
1992: Inoue M; Yamada H; Hashimoto Y; Yasukochi T; Hamaguchi K; Miki T; Horiuchi T; Imoto T
Stabilization of a protein by removal of unfavorable abnormal pKa: substitution of undissociable residue for glutamic acid-35 in chicken lysozyme.
Biochemistry 1992;31(37):8816-21.
1992: Inoue M; Yamada H; Yasukochi T; Kuroki R; Miki T; Horiuchi T; Imoto T
Multiple role of hydrophobicity of tryptophan-108 in chicken lysozyme: structural stability, saccharide binding ability, and abnormal pKa of glutamic acid-35.
Biochemistry 1992;31(24):5545-53.
1992: Ito Y; Yamada H; Imoto T
Colorimetric assay for lysozyme using Micrococcus luteus labeled with a blue dye, Remazol brilliant blue R, as a substrate.
Chemical & pharmaceutical bulletin 1992;40(6):1523-6.
1992: Koga H; Mori N; Yamada H; Nishimura Y; Tokuda K; Kato K; Imoto T
Endo- and aminopeptidase activities of rat cathepsin H.
Chemical & pharmaceutical bulletin 1992;40(4):965-70.
1991: Koga H; Mori N; Yamada H; Nishimura Y; Tokuda K; Kato K; Imoto T
Rat cathepsin H-catalyzed transacylation: comparisons of the mechanism and the specificity with papain-superfamily proteases.
Journal of biochemistry 1991;110(6):939-44.
1991: Himeno M; Nakamura K; Tanaka Y; Yamada H; Imoto T; Kato K
Mechanisms of a conversion from membrane associated lysosomal acid phosphatase to content forms.
Biochemical and biophysical research communications 1991;180(3):1483-9.
1991: Ueda T; Yamada H; Sakamoto N; Abe Y; Kawano K; Terada Y; Imoto T
Preparation and properties of a lysozyme derivative in which two domains are cross-linked intramolecularly between Trp62 and Asp101.
Journal of biochemistry 1991;110(5):719-25.
1991: Koga H; Yamada H; Nishimura Y; Kato K; Imoto T
Multiple proteolytic action of rat liver cathepsin B: specificities and pH-dependences of the endo- and exopeptidase activities.
Journal of biochemistry 1991;110(2):179-88.
1991: Ueda T; Isakari Y; Aoki H; Yasukochi T; Masutomo S; Kawano K; Terada Y; Yamada H; Imoto T
1H-NMR study of the intramolecular interaction of a substrate analogue covalently attached to aspartic acid-101 in lysozyme.
Journal of biochemistry 1991;109(5):690-8.
1990: Koga H; Yamada H; Nishimura Y; Kato K; Imoto T
Comparative study on specificities of rat cathepsin L and papain: amino acid differences at substrate-binding sites are involved in their specificities.
Journal of biochemistry 1990;108(6):976-82.
1990: Ueda T; Yamada H; Aoki H; Imoto T
Effect of chemical modifications of tryptophan residues on the folding of reduced hen egg-white lysozyme.
Journal of biochemistry 1990;108(5):886-92.
1990: Yamada H; Yamashita T; Domoto H; Imoto T
Reaction of hen egg-white lysozyme with tetranitromethane: a new side reaction, oxidative bond cleavage at glycine 104, and sequential nitration of three tyrosine residues.
Journal of biochemistry 1990;108(3):432-40.
1990: Ito Y; Yamada H; Nakamura S; Imoto T
Purification, amino acid sequence, and some properties of rabbit kidney lysozyme.
Journal of biochemistry 1990;107(2):236-41.
1987: Imoto T; Yamada H; Yasukochi T; Yamada E; Ito Y; Ueda T; Nagatani H; Miki T; Horiuchi T
Point mutation of alanine (31) to valine prohibits the folding of reduced lysozyme by sulfhydryl-disulfide interchange.
Protein engineering 1987;1(4):333-8.
1987: Miki T; Yasukochi T; Nagatani H; Furuno M; Orita T; Yamada H; Imoto T; Horiuchi T
Construction of a plasmid vector for the regulatable high level expression of eukaryotic genes in Escherichia coli: an application to overproduction of chicken lysozyme.
Protein engineering 1987;1(4):327-32.
1987: Ueda T; Yamada H; Imoto T
Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of Leu129 or Asp119.
Protein engineering 1987;1(3):189-93.
1985: Yamada H; Ueda T; Kuroki R; Fukumura T; Yasukochi T; Hirabayashi T; Fujita K; Imoto T
Isolation and characterization of 101-beta-lysozyme that possesses the beta-aspartyl sequence at aspartic acid-101.
Biochemistry 1985;24(27):7953-9.

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