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Nobuya Inagaki

Research Profile

Chemicals & Drugs

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Mouse
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Type 2 Diabetes Mellitus

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TOP 3
Daisuke Tanaka; Koichiro Yasuda; Shogo Funakoshi; Akio Koizumi; Yasushi Kondo; Kazuaki Nagashima; Mayumi Sasaki; Nobuya Inagaki
Exome sequencing identifies a new candidate mutation for susceptibility to diabetes in a family with highly aggregated type 2 diabetes.
Erina Joo; Tetsuro Matsunaga; Atsushi Muraoka; Daniela Nasteska; Kenichiro Shide; Kazuyo Suzuki; Kinsuke Tsuda; Hidemi Tsuji; Shunsuke Yamane; Toru Fukushima; Akihiro Hamasaki; Norio Harada; Tatsuya Hayashi; Nobuya Inagaki
Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice.
S-I Harashima; M Aono; Y Fujita; T Koizumi; Y Murata; M Ogura; M Seike; D Tanaka; Y Wang; S Yamane; Nobuya Inagaki
Efficacy and safety of switching from basal insulin to sitagliptin in Japanese type 2 diabetes patients.

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2013: Daisuke Tanaka; Koichiro Yasuda; Shogo Funakoshi; Akio Koizumi; Yasushi Kondo; Kazuaki Nagashima; Mayumi Sasaki; Nobuya Inagaki
Exome sequencing identifies a new candidate mutation for susceptibility to diabetes in a family with highly aggregated type 2 diabetes.
Molecular genetics and metabolism 2013;109(1):112-7.
2013: Erina Joo; Tetsuro Matsunaga; Atsushi Muraoka; Daniela Nasteska; Kenichiro Shide; Kazuyo Suzuki; Kinsuke Tsuda; Hidemi Tsuji; Shunsuke Yamane; Toru Fukushima; Akihiro Hamasaki; Norio Harada; Tatsuya Hayashi; Nobuya Inagaki
Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice.
Nutrition (Burbank, Los Angeles County, Calif.) 2013;29(3):549-55.
2013: S-I Harashima; M Aono; Y Fujita; T Koizumi; Y Murata; M Ogura; M Seike; D Tanaka; Y Wang; S Yamane; Nobuya Inagaki
Efficacy and safety of switching from basal insulin to sitagliptin in Japanese type 2 diabetes patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2013;45(3):231-8.
2013: Kazuyo Suzuki; Kentaro Toyoda; Shunsuke Yamane; Akihiro Hamasaki; Norio Harada; Takanari Harada; Erina Joo; Kazuaki Nagashima; Yasuhiko Nakamura; Daniela Nasteska; Kazuki Sasaki; Kimitaka Shibue; Nobuya Inagaki
Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity.
The Journal of biological chemistry 2013;288(3):1929-38.
2013: Shin-ichi Harashima; Shimpei Fujimoto; Toru Fukushima; Akihiro Hamasaki; Norio Harada; Kazuaki Nagashima; Yuko Nakahigashi; Yuichi Nishi; Masahito Ogura; Mayumi Sasaki; Yutaka Seino; Daisuke Tanaka; Shunsuke Yamane; Nobuya Inagaki
Self-monitoring of blood glucose (SMBG) improves glycaemic control in oral hypoglycaemic agent (OHA)-treated type 2 diabetes (SMBG-OHA study).
Diabetes/metabolism research and reviews 2013;29(1):77-84.
2012: Yasuhiko Nakamura; Kasane Ogura; Masahito Ogura; Daisuke Tanaka; Nobuya Inagaki
SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice.
FEBS letters 2012;586(23):4076-81.
2012: Nobuya Inagaki
[109th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 9. Incretin-based therapy for type 2 diabetes mellitus].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(9):2698-705.
2012: Nobuya Inagaki; Tomonori Oura; Hitoshi Saito; Yoshihito Atsumi; Takeshi Imaoka
Efficacy and safety profile of exenatide once weekly compared with insulin once daily in Japanese patients with type 2 diabetes treated with oral antidiabetes drug(s): results from a 26-week, randomized, open-label, parallel-group, multicenter, noninferiority study.
Clinical therapeutics 2012;34(9):1892-908.e1.
2012: Masahito Ogura; Nobuya Inagaki
[DPP-4 inhibitors and GLP-1 receptor agonists].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 6():201-5.
2012: Kazuaki Nagashima; Nobuya Inagaki
[The pathophysiology, diagnosis, and treatment for neonatal hypoglycemia].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 5():667-70.
2012: Kazuaki Nagashima; Nobuya Inagaki
[The pathophysiology, diagnosis, and treatment for neonatal diabetes mellitus].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 5():38-42.
2012: Kazuaki Nagashima; Nobuya Inagaki
[Diagnostic examination of type 2 diabetes mellitus].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 3():426-32.
2012: Shunsuke Yamane; Nobuya Inagaki
[Clinical biomarkers for diabetes mellitus].
Nihon rinsho. Japanese journal of clinical medicine 2012;70(5):846-51.
2011: Kaori Ikeda; Shimpei Fujimoto; Masashi Goto; Akihiro Hamasaki; Takashi Kawamura; Kenichiro Shide; Chizumi Yamada; Nobuya Inagaki
Impact of endogenous and exogenous insulin on basal energy expenditure in patients with type 2 diabetes under standard treatment.
The American journal of clinical nutrition 2011;94(6):1513-8.
2011: Shimpei Fujimoto; Eri Mukai; Nobuya Inagaki
Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreatic β cells.
Progress in biophysics and molecular biology 2011;107(2):304-10.
2011: Shin-ichi Harashima; Takahiko Horiuchi; Yutaka Seino; Yu Wang; Nobuya Inagaki
Purkinje cell protein 4 positively regulates neurite outgrowth and neurotransmitter release.
Journal of neuroscience research 2011;89(10):1519-30.
2011: Hiroyuki Fujimoto; Xibao Liu; Naoki Mochizuki; Eri Mukai; Teru Okitsu; Kentaro Toyoda; Shinji Uemoto; Xiaotong Zhuang; Nobuya Inagaki
Three-dimensional ex vivo imaging and analysis of intraportal islet transplants.
Transplant international : official journal of the European Society for Organ Transplantation 2011;24(8):839-44.
2011: Eri Mukai; Shimpei Fujimoto; Nobuya Inagaki
[Severe hypoglycemia by combination therapy with dipeptidyl peptidase-4 (DPP-4) inhibitors and sulfonylureas].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(5):907-11.
2011: Yuichi Nishi; Mayumi Sasaki; Hiroki Sato; Yuichi Sato; Yumiko Tahara; Shimpei Fujimoto; Eri Mukai; Yasuhiko Nakamura; Nobuya Inagaki
Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-1.
The Biochemical journal 2011;435(2):421-30.
2011: Daisuke Tanaka; Kazuaki Nagashima; Mayumi Sasaki; Chizumi Yamada; Shogo Funakoshi; Kimiyo Akitomo; Katsunobu Takenaka; Kouji Harada; Akio Koizumi; Nobuya Inagaki
GCKR mutations in Japanese families with clustered type 2 diabetes.
Molecular genetics and metabolism 2011;102(4):453-60.
2011: Nobuya Inagaki
[Current status and future prospects of diabetes therapy].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(3):707-11.
2011: Eiichi Ogawa; Masaya Hosokawa; Norio Harada; Shunsuke Yamane; Akihiro Hamasaki; Kentaro Toyoda; Shimpei Fujimoto; Yoshihito Fujita; Kazuhito Fukuda; Katsushi Tsukiyama; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice.
Biochemical and biophysical research communications 2011;404(1):115-20.
2011: Akihiro Hamasaki; Nobuya Inagaki
[DPP-4 inhibitors, GLP-1 receptor agonists].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 1():654-61.
2011: Eri Mukai; Shimpei Fujimoto; Hiroki Sato; Chitose Oneyama; Rieko Kominato; Yuichi Sato; Mayumi Sasaki; Yuichi Nishi; Masato Okada; Nobuya Inagaki
Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner.
Diabetes 2011;60(1):218-26.
2010: Taeko Uonaga; Kentaro Toyoda; Teru Okitsu; Xiaotong Zhuang; Shunsuke Yamane; Shinji Uemoto; Nobuya Inagaki
FGF-21 enhances islet engraftment in mouse syngeneic islet transplantation model.
Islets 2010;2(4):247-51.
2010: Shimpei Fujimoto; Nobuya Inagaki; Yutaka Seino
[Pancreatic polypeptide (PP)].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 7():560-2.
2010: Y Fujita; M Hosokawa; Shimpei Fujimoto; Eri Mukai; A Abudukadier; A Obara; M Ogura; Yasuyuki Nakamura; K Toyoda; K Nagashima; Yutaka Seino; Nobuya Inagaki
Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice.
Diabetologia 2010;53(7):1472-81.
2010: Norio Harada; Nobuya Inagaki
[Incretin and incretin-based therapies].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(5):931-42.
2010: Yukiko Kawasaki; S Harashima; M Sasaki; Eri Mukai; Yoshio Nakamura; Norio Harada; Kentaro Toyoda; Akihiro Hamasaki; S Yamane; Chizumi Yamada; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(5):311-7.
2010: Masahito Ogura; Yasuhiko Nakamura; Daisuke Tanaka; Xiaotong Zhuang; Yoshihito Fujita; Akio Obara; Akihiro Hamasaki; Masaya Hosokawa; Nobuya Inagaki
Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1.
Biochemical and biophysical research communications 2010;393(1):73-8.
2010: Kana Toyama; Atsushi Yonezawa; Masahiro Tsuda; Satohiro Masuda; Ikuko Yano; Tomohiro Terada; Riyo Osawa; Toshiya Katsura; Masaya Hosokawa; Shimpei Fujimoto; Nobuya Inagaki; Ken-Ichi Inui
Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.
Pharmacogenetics and genomics 2010;20(2):135-8.
2010: Makiko Shimodahira; Shimpei Fujimoto; Eri Mukai; Yasuhiko Nakamura; Yuichi Nishi; Mayumi Sasaki; Yuichi Sato; Hiroki Sato; Masaya Hosokawa; Kazuaki Nagashima; Yutaka Seino; Nobuya Inagaki
Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism.
The Journal of endocrinology 2010;204(1):37-46.
2009: Eri Mukai; Kentaro Toyoda; Hiroyuki Kimura; Hidekazu Kawashima; Hiroyuki Fujimoto; Masashi Ueda; Takashi Temma; Konomu Hirao; Kenji Nagakawa; Hideo Saji; Nobuya Inagaki
GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging.
Biochemical and biophysical research communications 2009;389(3):523-6.
2009: Xibao Liu; Norio Harada; Shunsuke Yamane; Lisa Kitajima; Saeko Uchida; Akihiro Hamasaki; Eri Mukai; Kentaro Toyoda; Chizumi Yamada; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice.
Life sciences 2009;84(25-26):876-81.
2008: Shogo Funakoshi; Shimpei Fujimoto; Akihiro Hamasaki; Hideya Fujiwara; Yoshihito Fujita; Kaori Ikeda; Yoshiyuki Hamamoto; Masaya Hosokawa; Yutaka Seino; Nobuya Inagaki
Analysis of factors influencing pancreatic beta-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure.
Diabetes research and clinical practice 2008;82(3):353-8.
2008: Rei Naitoh; Kazumasa Miyawaki; Norio Harada; Wataru Mizunoya; Kentaro Toyoda; Tohru Fushiki; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice.
Biochemical and biophysical research communications 2008;376(1):21-5.
2008: Norio Harada; Mitsuo Fukushima; Kentaro Toyoda; Ryoji Mitsui; Tomoyo Izuka; Ataru Taniguchi; Yoshikatsu Nakai; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Factors responsible for elevation of 1-h postchallenge plasma glucose levels in Japanese men.
Diabetes research and clinical practice 2008;81(3):284-9.
2008: Mariko Sassa; Yuichiro Yamada; Masaya Hosokawa; Kazuhito Fukuda; Shimpei Fujimoto; Kentaro Toyoda; Katsushi Tsukiyama; Yutaka Seino; Nobuya Inagaki
Glycemic instability in type 1 diabetic patients: Possible role of ketosis or ketoacidosis at onset of diabetes.
Diabetes research and clinical practice 2008;81(2):190-5.
2008: Rieko Kominato; Shimpei Fujimoto; Eri Mukai; Yasuyuki Nakamura; Koichiro Nabe; Makiko Shimodahira; Yuichi Nishi; Shogo Funakoshi; Yutaka Seino; Nobuya Inagaki
Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.
Diabetologia 2008;51(7):1226-35.
2008: Yo Aramaki; Hirokazu Mitsuoka; Masako Toyohara; Toshikazu Jinnai; Kazushi Kanatani; Katsuyuki Nakajima; Eri Mukai; Yuichiro Yamada; Toru Kita; Nobuya Inagaki; Noriaki Kume
Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells.
Atherosclerosis 2008;198(2):272-9.
2008: Hideya Fujiwara; Masaya Hosokawa; Xiaorong Zhou; Shimpei Fujimoto; Kazuhito Fukuda; Kentaro Toyoda; Yuichi Nishi; Yoshihito Fujita; Kotaro Yamada; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Curcumin inhibits glucose production in isolated mice hepatocytes.
Diabetes research and clinical practice 2008;80(2):185-91.
2008: Kotaro Yamada; Masaya Hosokawa; Chizumi Yamada; Rie Watanabe; Shimpei Fujimoto; Hideya Fujiwara; Masaru Kunitomo; Toshihiro Miura; Tetsuo Kaneko; Kinsuke Tsuda; Yutaka Seino; Nobuya Inagaki
Dietary corosolic acid ameliorates obesity and hepatic steatosis in KK-Ay mice.
Biological & pharmaceutical bulletin 2008;31(4):651-5.
2008: Yoshihito Fujita; Mitsuo Fukushima; Haruhiko Suzuki; Ataru Taniguchi; Yoshikatsu Nakai; Akira Kuroe; Koichiro Yasuda; Masaya Hosokawa; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Short-term intensive glycemic control improves vibratory sensation in type 2 diabetes.
Diabetes research and clinical practice 2008;80(1):e16-9.
2008: Kotaro Yamada; Masaya Hosokawa; Shimpei Fujimoto; Hideya Fujiwara; Yoshihito Fujita; Norio Harada; Chizumi Yamada; Mitsuo Fukushima; Naoya Ueda; Tetsuo Kaneko; Futoshi Matsuyama; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Effect of corosolic acid on gluconeogenesis in rat liver.
Diabetes research and clinical practice 2008;80(1):48-55.
2008: Kentaro Toyoda; Teru Okitsu; Shunsuke Yamane; Taeko Uonaga; Xibao Liu; Norio Harada; Shinji Uemoto; Yutaka Seino; Nobuya Inagaki
GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis.
Biochemical and biophysical research communications 2008;367(4):793-8.
2008: Kentaro Toyoda; Mitsuo Fukushima; Ryoji Mitsui; Norio Harada; Hidehiko Suzuki; Tomomi Takeda; Ataru Taniguchi; Yoshikatsu Nakai; Toshiko Kawakita; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Factors responsible for age-related elevation in fasting plasma glucose: a cross-sectional study in Japanese men.
Metabolism: clinical and experimental 2008;57(2):299-303.
2008: Yasuhiko Nakamura; Masahito Ogura; Daisuke Tanaka; Nobuya Inagaki
Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
Biochemical and biophysical research communications 2008;366(1):174-9.
2008: Chizumi Yamada; Yuichiro Yamada; Katsushi Tsukiyama; Kotaro Yamada; Nobuyuki Udagawa; Naoyuki Takahashi; Kiyoshi Tanaka; Daniel J Drucker; Yutaka Seino; Nobuya Inagaki
The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.
Endocrinology 2008;149(2):574-9.
2008: Norio Harada; Yuichiro Yamada; Katsushi Tsukiyama; Chizumi Yamada; Yasuhiko Nakamura; Eri Mukai; Akihiro Hamasaki; Xibao Liu; Kentaro Toyoda; Yutaka Seino; Nobuya Inagaki
A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.
American journal of physiology. Endocrinology and metabolism 2008;294(1):E61-8.
2007: Chizumi Yamada; Yuichiro Yamada; Katsushi Tsukiyama; Kotaro Yamada; Shunsuke Yamane; Norio Harada; Kazumasa Miyawaki; Yutaka Seino; Nobuya Inagaki
Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes.
Biochemical and biophysical research communications 2007;364(1):175-80.
2007: Shimpei Fujimoto; Koichiro Nabe; Mihoko Takehiro; Makiko Shimodahira; Mariko Kajikawa; Tomomi Takeda; Eri Mukai; Nobuya Inagaki; Yutaka Seino
Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production.
Diabetes research and clinical practice 2007;77 Suppl 1():S2-10.
2007: Akira Takahashi; Kazuaki Nagashima; Akihiro Hamasaki; Naomitsu Kuwamura; Yukiko Kawasaki; Hiroki Ikeda; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Sulfonylurea and glinide reduce insulin content, functional expression of K(ATP) channels, and accelerate apoptotic beta-cell death in the chronic phase.
Diabetes research and clinical practice 2007;77(3):343-50.
2007: Ataru Taniguchi; Mitsuo Fukushima; Akira Kuroe; Kenji Sakaguchi; Hiroko Hashimoto; Ikuko Yoshioka; Naomi Kitatani; Tomoko Tsuji; Michihiro Ohya; Minako Ohgushi; Shoichiro Nagasaka; Okihisa Isogai; Yoshikatsu Nakai; Nobuya Inagaki; Yutaka Seino
Metabolic syndrome, insulin resistance, and atherosclerosis in Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2007;56(8):1099-103.
2007: N Kitatani; Ataru Taniguchi; Mitsuo Fukushima; Yoshikatsu Nakai; Shoichiro Nagasaka; Minako Ohgushi; Michihiro Ohya; Akira Kuroe; Nobuya Inagaki; Yutaka Seino
Association of serum resistin with TNF system activity in Japanese type 2 diabetic patients.
Diabetes & metabolism 2007;33(2):156-7.
2007: Minako Ohgushi; Ataru Taniguchi; Mitsuo Fukushima; Yoshikatsu Nakai; Akira Kuroe; Michihiro Ohya; Shoichiro Nagasaka; Yoshiro Taki; Satoru Yoshii; Kazunari Matsumoto; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Soluble tumor necrosis factor receptor 2 is independently associated with pulse wave velocity in nonobese Japanese patients with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2007;56(4):571-7.
2007: Akihiro Hamasaki; Yuichiro Yamada; Takeshi Kurose; Nobuhiro Ban; Kazuaki Nagashima; Akira Takahashi; Shimpei Fujimoto; Dai Shimono; Michio Fujiwara; Shinya Toyokuni; Yutaka Seino; Nobuya Inagaki
Adult pancreatic islets require differential pax6 gene dosage.
Biochemical and biophysical research communications 2007;353(1):40-6.
2007: D Nabeya; Ataru Taniguchi; Mitsuo Fukushima; Yoshikatsu Nakai; K Matsumoto; Akira Kuroe; Minako Ohgushi; Michihiro Ohya; Shoichiro Nagasaka; Nobuya Inagaki; Yutaka Seino
Soluble vascular cell adhesion molecule-1 is independently associated with soluble tumor necrosis factor receptor 2 in Japanese type 2 diabetic patients.
Diabetes & metabolism 2007;33(1):81-2.
2007: Kotaro Yamada; Masaya Hosokawa; Shimpei Fujimoto; Kazuaki Nagashima; Kazuhito Fukuda; Hideya Fujiwara; Eiichi Ogawa; Yoshihito Fujita; Naoya Ueda; Futoshi Matsuyama; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
The spontaneously diabetic Torii rat with gastroenteropathy.
Diabetes research and clinical practice 2007;75(2):127-34.
2006: Chizumi Yamada; Kazuaki Nagashima; Akira Takahashi; Hiroyuki Ueno; Yukiko Kawasaki; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis.
European journal of pharmacology 2006;553(1-3):67-72.
2006: Yuichiro Yamada; Kazuhito Fukuda; Shimpei Fujimoto; Masaya Hosokawa; Katsushi Tsukiyama; Kazuaki Nagashima; Mitsuo Fukushima; Haruhiko Suzuki; Kentaro Toyoda; Mariko Sassa; Shogo Funakoshi; Nobuya Inagaki; Ataru Taniguchi; T Shun Sato; Shinichi Matsumoto; Koichi Tanaka; Yutaka Seino
SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes.
Diabetes research and clinical practice 2006;74(3):222-6.
2006: Mariko Sassa; Kazuhito Fukuda; Shimpei Fujimoto; Kentaro Toyoda; Yoshihito Fujita; Shinichi Matsumoto; Teru Okitsu; Yasuhiro Iwanaga; Hirofumi Noguchi; Hideo Nagata; Yukihide Yonekawa; Takeshi Ohara; Masahiko Okamoto; Koichi Tanaka; Yutaka Seino; Nobuya Inagaki; Yuichiro Yamada
A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement.
Diabetes research and clinical practice 2006;73(3):235-40.
2006: Koichiro Nabe; Shimpei Fujimoto; Makiko Shimodahira; Rieko Kominato; Yuichi Nishi; Shogo Funakoshi; Eri Mukai; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.
Endocrinology 2006;147(6):2717-27.
2006: Ryoji Mitsui; Mitsuo Fukushima; Yuichi Nishi; Naoya Ueda; Haruhiko Suzuki; Ataru Taniguchi; Yoshikatsu Nakai; Toshiko Kawakita; Takeshi Kurose; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Factors responsible for deteriorating glucose tolerance in newly diagnosed type 2 diabetes in Japanese men.
Metabolism: clinical and experimental 2006;55(1):53-8.
2005: Hidehiko Suzuki; Mitsuo Fukushima; Shigeru Okamoto; Osamu Takahashi; Takuro Shimbo; Takeshi Kurose; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino; Tsuguya Fukui
Effects of thorough mastication on postprandial plasma glucose concentrations in nonobese Japanese subjects.
Metabolism: clinical and experimental 2005;54(12):1593-9.
2005: Y Kawasaki; Ataru Taniguchi; Mitsuo Fukushima; Yoshikatsu Nakai; Akira Kuroe; Michihiro Ohya; Shoichiro Nagasaka; Yuichiro Yamada; Nobuya Inagaki; Yutaka Seino
Soluble TNF receptors and albuminuria in non-obese Japanese type 2 diabetic patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(10):617-21.
2005: Michihiro Ohya; Ataru Taniguchi; Mitsuo Fukushima; Yoshikatsu Nakai; Yukiko Kawasaki; Shoichiro Nagasaka; Akira Kuroe; Yoshiro Taki; Satoru Yoshii; Masaya Hosokawa; Nobuya Inagaki; Yutaka Seino
Three measures of tumor necrosis factor alpha activity and insulin resistance in nonobese Japanese type 2 diabetic patients.
Metabolism: clinical and experimental 2005;54(10):1297-301.
2005: Kazuhito Fukuda; Nobuya Inagaki; Yutaka Seino
[Pancreatic polypeptide].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():521-3.
2004: Koh Nagata; Akitsugu Yamamoto; Nobuhiro Ban; Arowu R Tanaka; Michinori Matsuo; Noriyuki Kioka; Nobuya Inagaki; Kazumitsu Ueda
Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles.
Biochemical and biophysical research communications 2004;324(1):262-8.
2003: Haruaki Nakaya; Takashi Miki; Susumu Seino; Katsuya Yamada; Nobuya Inagaki; Masashi Suzuki; Toshiaki Sato; Mitsuhiko Yamada; Kenji Matsushita; Yoshihisa Kurachi; Makoto Arita
[Molecular and functional diversity of ATP-sensitive K+ channels: the pathophysiological roles and potential drug targets].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2003;122(3):243-50.
2002: Takehiko Ogura; Tetsushi Furukawa; Tetsuya Toyozaki; Katsuya Yamada; Ya-Juan Zheng; Yoshifumi Katayama; Haruaki Nakaya; Nobuya Inagaki
ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(8):863-5.
1999: M Suzuki; K Fujikura; K Kotake; Nobuya Inagaki; Susumu Seino; Kuniaki Takata
Immuno-localization of sulphonylurea receptor 1 in rat pancreas.
Diabetologia 1999;42(10):1204-11.
1999: Yasuhiro Sunaga; Nobuya Inagaki; Tohru Gonoi; Yuichiro Yamada; H Ishida; Yutaka Seino; Susumu Seino
Troglitazone but not pioglitazone affects ATP-sensitive K(+) channel activity.
European journal of pharmacology 1999;381(1):71-6.
1998: J A Sánchez; Tohru Gonoi; Nobuya Inagaki; T Katada; Susumu Seino
Modulation of reconstituted ATP-sensitive K(+)-channels by GTP-binding proteins in a mammalian cell line.
The Journal of physiology 1998;507 ( Pt 2)():315-24.
1997: M Suzuki; K Kotake; K Fujikura; Nobuya Inagaki; Takahiro Suzuki; Tohru Gonoi; Susumu Seino; Kuniaki Takata
Kir6.1: a possible subunit of ATP-sensitive K+ channels in mitochondria.
Biochemical and biophysical research communications 1997;241(3):693-7.
1997: K Kotake; Nobuaki Ozaki; M Mizuta; S Sekiya; Nobuya Inagaki; Susumu Seino
Noc2, a putative zinc finger protein involved in exocytosis in endocrine cells.
The Journal of biological chemistry 1997;272(47):29407-10.
1997: Takashi Miki; F Tashiro; Toshihiko Iwanaga; K Nagashima; Hideyuki Yoshitomi; Hajime Aihara; Y Nitta; Tohru Gonoi; Nobuya Inagaki; J i Miyazaki; Susumu Seino
Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11969-73.
1997: Nobuya Inagaki; Susumu Seino
[ATP sensitive potassium channels--Kir6.2 gene].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl():452-7.
1997: Kunihiro Ueda; Nobuya Inagaki; Susumu Seino
MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.
The Journal of biological chemistry 1997;272(37):22983-6.
1997: Nobuya Inagaki; Tohru Gonoi; Susumu Seino
[The sulfonylurea receptor].
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(9):1067-80.
1997: M Suzuki; K Fujikura; Nobuya Inagaki; Susumu Seino; Kuniaki Takata
Localization of the ATP-sensitive K+ channel subunit Kir6.2 in mouse pancreas.
Diabetes 1997;46(9):1440-4.
1997: Nobuya Inagaki; Tohru Gonoi; Susumu Seino
Subunit stoichiometry of the pancreatic beta-cell ATP-sensitive K+ channel.
FEBS letters 1997;409(2):232-6.
1997: Hideyuki Yoshitomi; Y Fujii; Masaru Miyazaki; N Nakajima; Nobuya Inagaki; Susumu Seino
Involvement of MAP kinase and c-fos signaling in the inhibition of cell growth by somatostatin.
The American journal of physiology 1997;272(5 Pt 1):E769-74.
1997: Susumu Seino; Nobuya Inagaki; N Namba; C H Wang; K Kotake; K Nagashima; Takashi Miki; L Aguilar-Bryan; J Bryan; Tohru Gonoi
Molecular basis of functional diversity of ATP-sensitive K+ channels.
The Japanese journal of physiology 1997;47 Suppl 1():S3-4.
1996: Nobuya Inagaki; H Kuromi; Susumu Seino
PACAP/VIP receptors in pancreatic beta-cells: their roles in insulin secretion.
Annals of the New York Academy of Sciences 1996;805():44-51; discussion 52-3.
1996: Y Watabe; Hiroaki Kuramochi; Y Furuya; Nobuya Inagaki; Susumu Seino; Sadao Kimura; Jun Shimazaki
Identification of histone H2A.X as a growth factor secreted by an androgen-independent subline of mouse mammary carcinoma cells.
The Journal of biological chemistry 1996;271(41):25126-30.
1996: T Kadota; T Yamaai; Y Saito; Y Akita; S Kawashima; Kayoko Moroi; Nobuya Inagaki; K Kadota
Expression of dopamine transporter at the tips of growing neurites of PC12 cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(9):989-96.
1996: N Namba; Nobuya Inagaki; Tohru Gonoi; Y Seino; Susumu Seino
Kir2.2v: a possible negative regulator of the inwardly rectifying K+ channel Kir2.2.
FEBS letters 1996;386(2-3):211-4.
1996: Nobuya Inagaki; Tohru Gonoi; JP Clement; C Z Wang; Lydia Aguilar-Bryan; Joseph Bryan; Susumu Seino
A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.
Neuron 1996;16(5):1011-7.
1996: C Z Wang; N Namba; Tohru Gonoi; Nobuya Inagaki; Susumu Seino
Cloning and pharmacological characterization of a fourth P2X receptor subtype widely expressed in brain and peripheral tissues including various endocrine tissues.
Biochemical and biophysical research communications 1996;220(1):196-202.
1995: Nobuya Inagaki; Tohru Gonoi; JP Clement; N Namba; J Inazawa; María Tinaquero; Lydia Aguilar-Bryan; Susumu Seino; Joseph Bryan
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Science (New York, N.Y.) 1995;270(5239):1166-70.
1995: Nobuya Inagaki; J Inazawa; Susumu Seino
cDNA sequence, gene structure, and chromosomal localization of the human ATP-sensitive potassium channel, uKATP-1, gene (KCNJ8).
Genomics 1995;30(1):102-4.
1995: Nobuya Inagaki; H Kuromi; Tohru Gonoi; Y Okamoto; H Ishida; Y Seino; T Kaneko; T Iwanaga; Susumu Seino
Expression and role of ionotropic glutamate receptors in pancreatic islet cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(8):686-91.
1995: Nobuya Inagaki; Y Tsuura; N Namba; K Masuda; Tohru Gonoi; Minoru Horie; Y Seino; M Mizuta; Susumu Seino
Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart.
The Journal of biological chemistry 1995;270(11):5691-4.
1995: K Yorimitsu; Kayoko Moroi; Nobuya Inagaki; T Saito; Yoshiaki Masuda; T Masaki; Susumu Seino; Sumiko Kimura
Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
Biochemical and biophysical research communications 1995;208(2):721-7.
1994: Y Fujii; Tohru Gonoi; Y Yamada; K Chihara; Nobuya Inagaki; Susumu Seino
Somatostatin receptor subtype SSTR2 mediates the inhibition of high-voltage-activated calcium channels by somatostatin and its analogue SMS 201-995.
FEBS letters 1994;355(2):117-20.
1994: Nobuya Inagaki; M Mizuta; Susumu Seino
Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells.
Journal of biochemistry 1994;116(2):239-42.
1994: Tohru Gonoi; N Mizuno; Nobuya Inagaki; H Kuromi; Y Seino; J Miyazaki; Susumu Seino
Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6.
The Journal of biological chemistry 1994;269(25):16989-92.
1994: M Mizuta; Nobuya Inagaki; Y Nemoto; S Matsukura; M Takahashi; Susumu Seino
Synaptotagmin III is a novel isoform of rat synaptotagmin expressed in endocrine and neuronal cells.
The Journal of biological chemistry 1994;269(16):11675-8.
1994: Nobuya Inagaki; H Yoshida; M Mizuta; N Mizuno; Y Fujii; Tohru Gonoi; J Miyazaki; Susumu Seino
Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2679-83.
1993: H Yoshida; S Hasegawa; H Kuromi; Nobuya Inagaki; Susumu Seino; K Takahashi; K Sato
A variant form of laminin is responsible for the neurite outgrowth-promoting activity in conditioned medium from a squamous carcinoma cell line.
Connective tissue research 1993;30(1):23-35.