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Mitchell Avery
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11
Desai, Prashant
11
Tekwani, Babu
10
Chittiboyina, Amar
8
Avery, Bonnie
6
Jung, Jae-Chul
6
Pradhan, Anupam
5
Pershadsingh, Harrihar
5
Sabnis, Yogesh
5
Williamson, John
5
kurtz, theodore
4
Rosenthal, Philip
4
Walker, Larry
4
Parshikov, Igor
4
Patny, Akshay
4
Muraleedharan, Kannoth
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All Publications
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2009: Pradhan Anupam; Tripathi Abhai K; Desai Prashant V; Mukherjee Prasenjit K; Avery Mitchell A; Walker Larry A; Tekwani Babu L
Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.
Biochimie 2009;91(11-12):1509-17.
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2009: Jain Sandeep; Abraham Ioana; Carvalho Paulo; Kuang Ye-Hong; Shaala Lamiaa A; Youssef Diaa T A; Avery Mitchell A; Chen Zhe-Sheng; El Sayed Khalid A
Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling.
Journal of natural products 2009;72(7):1291-8.
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2009: Pradhan Anupam; Mukherjee Prasenjit; Tripathi Abhai K; Avery Mitchell A; Walker Larry A; Tekwani Babu L
Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants.
Molecular and cellular biochemistry 2009;325(1-2):141-8.
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2009: Zhang Shuang-Qing; Vinnakota Harsha; Jung Jae-Chul; Carvalho Paulo; Chittiboyina Amar G; Avery Mitchell A; Avery Bonnie A
Determination of a novel epothilone D analog (AV-EPO-106) in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry.
Biomedical chromatography : BMC 2009;23(3):302-7.
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2008: Fu Xiang; Li Xing-Cong; Smillie Troy J; Carvalho Paulo; Mabusela Wilfred; Syce James; Johnson Quinton; Folk William; Avery Mitchell A; Khan Ikhlas A
Cycloartane glycosides from Sutherlandia frutescens.
Journal of natural products 2008;71(10):1749-53.
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2008: Li Ze; Watkins E Blake; Liu Hua; Chittiboyina Amar G; Carvalho Paulo B; Avery Mitchell A
1,3-Diaxially substituted trans-decalins: potential nonsteroidal human progesterone receptor inhibitors.
The Journal of organic chemistry 2008;73(19):7764-7.
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2008: Mukherjee Prasenjit; Desai Prashant V; Srivastava Anuradha; Tekwani Babu L; Avery Mitchell A
Probing the structures of leishmanial farnesyl pyrophosphate synthases: homology modeling and docking studies.
Journal of chemical information and modeling 2008;48(5):1026-40.
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2008: Mukherjee Prasenjit; Pradhan Anupam; Shah Falgun; Tekwani Babu L; Avery Mitchell A
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy.
Bioorganic & medicinal chemistry 2008;16(9):5254-65.
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2008: Li Lie; Pabbisetty Deepthi; Carvalho Paulo; Avery Mitchell A; Williamson John S; Avery Bonnie A
Ultra-performance liquid chromatography-tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;867(1):131-7.
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2008: Mukherjee Prasenjit; Desai Prashant; Ross Larry; White E Lucile; Avery Mitchell A
Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits.
Bioorganic & medicinal chemistry 2008;16(7):4138-49.
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2008: Srivastava Anuradha; Mukherjee Prasenjit; Desai Prashant V; Avery Mitchell A; Tekwani Babu L
Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target.
Infectious disorders drug targets 2008;8(1):16-30.
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2008: Li Lie; Pabbisetty Deepthi; Zhu Shiqian; Avery Mitchell A; Avery Bonnie A
Urinary excretion study of coenzyme Q10 in rats by ultra-performance liquid chromatography-mass spectrometry.
Journal of chromatographic science 2008;46(3):215-9.
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2008: Sayed Khalid A El; Khalil Ashraf A; Yousaf Muhammad; Labadie Guillermo; Kumar Gundluru M; Franzblau Scott G; Mayer Alejandro M S; Avery Mitchell A; Hamann Mark T
Semisynthetic studies on the manzamine alkaloids.
Journal of natural products 2008;71(3):300-8.
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2008: Li Lie; Pabbisetty Deepthi; Carvalho Paulo; Avery Mitchell A; Avery Bonnie A
Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration.
Journal of pharmaceutical and biomedical analysis 2008;46(1):137-42.
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2008: Choi Seoung-Ryoung; Mukherjee Prasenjit; Avery Mitchell A
The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs.
Current medicinal chemistry 2008;15(2):161-71.
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2008: Mizuno Cassia S; Chittiboyina Amar G; Kurtz Theodore W; Pershadsingh Harrihar A; Avery Mitchell A
Type 2 diabetes and oral antihyperglycemic drugs.
Current medicinal chemistry 2008;15(1):61-74.
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2007: Chittiboyina Amar G; Kumar Gundluru Mahesh; Carvalho Paulo B; Liu Yang; Zhou Yu-Dong; Nagle Dale G; Avery Mitchell A
Total synthesis and absolute configuration of laurenditerpenol: a hypoxia inducible factor-1 activation inhibitor.
Journal of medicinal chemistry 2007;50(25):6299-302.
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2007: Kim Tack-Joong; Lim Yong; Kim Dong-Woon; Kwon Jin-Sook; Son Ju-Hee; Jin Yong-Ri; Son Dong Ju; Jung Jae-Chul; Avery Mitchell A; Hong Jin Tae; Yun Yeo-Pyo
Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins.
Vascular pharmacology 2007;47(4):229-37.
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2007: Singh Nidhi; Avery Mitchell A; McCurdy Christopher R
Toward Mycobacterium tuberculosis DXR inhibitor design: homology modeling and molecular dynamics simulations.
Journal of computer-aided molecular design 2007;21(9):511-22.
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2007: Choi Seoung-ryoung; Pradhan Anupam; Hammond Nicholas L; Chittiboyina Amar G; Tekwani Babu L; Avery Mitchell A
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors.
Journal of medicinal chemistry 2007;50(16):3841-50.
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2007: Lim Yong; Kim Tack-Joong; Jin Yong-Ri; Kim Dong-Woon; Kwon Jin-Sook; Son Ju-Hee; Jung Jae-Chul; Avery Mitchell A; Son Dong Ju; Hong Jin Tae; Yun Yeo-Pyo
Epothilone B inhibits neointimal formation after rat carotid injury through the regulation of cell cycle-related proteins.
The Journal of pharmacology and experimental therapeutics 2007;321(2):648-55.
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2007: Choi Seoung-ryoung; Beeler Aaron B; Pradhan Anupam; Watkins E Blake; Rimoldi John M; Tekwani Babu; Avery Mitchell A
Generation of oxamic acid libraries: antimalarials and inhibitors of Plasmodium falciparum lactate dehydrogenase.
Journal of combinatorial chemistry 2007;9(2):292-300.
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2007: Singh Nidhi; Chevé Gweneal; Avery Mitchell A; McCurdy Christopher R
Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme.
Current pharmaceutical design 2007;13(11):1161-77.
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2006: Menon Rani B; Kannoth Muraleedharan M; Tekwani Babu L; Gut Jiri; Rosenthal Phillip J; Avery Mitchell A
A new library of C-16 modified artemisinin analogs and evaluation of their anti-parasitic activities.
Combinatorial chemistry & high throughput screening 2006;9(10):729-41.
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2006: Patny Akshay; Desai Prashant V; Avery Mitchell A
Ligand-supported homology modeling of the human angiotensin II type 1 (AT(1)) receptor: insights into the molecular determinants of telmisartan binding.
Proteins 2006;65(4):824-42.
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2006: Chittiboyina Amar G; Venkatraman Meenakshi S; Mizuno Cassia S; Desai Prashant V; Patny Akshay; Benson Stephen C; Ho Christopher I; Kurtz Theodore W; Pershadsingh Harrihar A; Avery Mitchell A
Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists.
Journal of medicinal chemistry 2006;49(14):4072-84.
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2006: Singh Nidhi; Chevé Gwénaël; Avery Mitchell A; McCurdy Christopher R
Comparative protein modeling of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme from Plasmodium falciparum: a potential target for antimalarial drug discovery.
Journal of chemical information and modeling 2006;46(3):1360-70.
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2006: Parshikov Igor A; Miriyala Brushapathy; Muraleedharan Kannoth M; Avery Mitchell A; Williamson John S
Microbial transformation of artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger.
Journal of industrial microbiology & biotechnology 2006;33(5):349-52.
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2006: Mora Flor D; Jones Deborah K; Desai Prashant V; Patny Akshay; Avery Mitchell A; Feller Dennis R; Smillie Troy; Zhou Yu-Dong; Nagle Dale G
Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells.
Journal of natural products 2006;69(4):547-52.
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2006: Patny Akshay; Desai Prashant V; Avery Mitchell A
Homology modeling of G-protein-coupled receptors and implications in drug design.
Current medicinal chemistry 2006;13(14):1667-91.
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2005: Burk Oliver; Arnold Katja A; Nussler Andreas K; Schaeffeler Elke; Efimova Ekaterina; Avery Bonnie A; Avery Mitchell A; Fromm Martin F; Eichelbaum Michel
Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.
Molecular pharmacology 2005;67(6):1954-65.
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2005: Watkins E Blake; Chittiboyina Amar G; Jung Jae-Chul; Avery Mitchell A
The epothilones and related analogues-a review of their syntheses and anti-cancer activities.
Current pharmaceutical design 2005;11(13):1615-53.
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2004: Sawant Swapnali S; Sylvester Paul W; Avery Mitchell A; Desai Prashant; Youssef Diaa T A; El Sayed Khalid A
Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine.
Journal of natural products 2004;67(12):2017-23.
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2004: Jung Jae-Chul; Kache Rajashaker; Vines Kimberly K; Zheng Yan-Song; Bijoy Panicker; Valluri Muralikrishna; Avery Mitchell A
Total syntheses of epothilones B and d.
The Journal of organic chemistry 2004;69(26):9269-84.
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2004: McLuskey Karen; Gibellini Federica; Carvalho Paulo; Avery Mitchell A; Hunter William N
Inhibition of Leishmania major pteridine reductase by 2,4,6-triaminoquinazoline: structure of the NADPH ternary complex.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1780-5.
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2004: Parshikov Igor A; Muraleedharan Kannoth M; Miriyala Bruhaspathy; Avery Mitchell A; Williamson John S
Hydroxylation of 10-deoxoartemisinin by Cunninghamella elegans.
Journal of natural products 2004;67(9):1595-7.
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2004: Tripathi Abhai K; Desai Prashant V; Pradhan Anupam; Khan Shabana I; Avery Mitchell A; Walker Larry A; Tekwani Babu L
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.
European journal of biochemistry / FEBS 2004;271(17):3488-502.
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2004: Venkatraman Meenakshi S; Chittiboyina Amar; Meingassner Josef; Ho Christopher I; Varani James; Ellis Charles N; Avery Mitchell A; Pershadsingh Harrihar A; Kurtz Theodore W; Benson Stephen C
Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases.
Archives of dermatological research 2004;296(3):97-104.
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2004: Desai P V; Avery M A
Structural characterization of vivapain-2 and vivapain-3, cysteine proteases from Plasmodium vivax: comparative protein modeling and docking studies.
Journal of biomolecular structure & dynamics 2004;21(6):781-90.
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2004: Parshikov I A; Muraleedharan K M; Avery M A; Williamson J S
Transformation of artemisinin by Cunninghamella elegans.
Applied microbiology and biotechnology 2004;64(6):782-6.
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2004: Benson Stephen C; Pershadsingh Harrihar A; Ho Christopher I; Chittiboyina Amar; Desai Prashant; Pravenec Michal; Qi Nianning; Wang Jiaming; Avery Mitchell A; Kurtz Theodore W
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
Hypertension 2004;43(5):993-1002.
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2004: Parshikov Igor A; Miriyala Bruhaspathy; Avery Mitchell A; Williamson John S
Hydroxylation of 10-deoxoartemisinin to 15-hydroxy-10-deoxoartemisinin by Aspergillus niger.
Biotechnology letters 2004;26(7):607-10.
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2004: Labadie Guillermo R; Choi Seoung Ryoung; Avery Mitchell A
Diamine derivatives with antiparasitic activities.
Bioorganic & medicinal chemistry letters 2004;14(3):615-9.
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2004: Bhagavathula Narasimharao; Nerusu Kamalakar C; Lal Ashish; Ellis Charles N; Chittiboyina Amar; Avery Mitchell A; Ho Christopher I; Benson Stephen C; Pershadsingh Harrihar A; Kurtz Theodore W; Varani James
Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes.
The Journal of investigative dermatology 2004;122(1):130-9.
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2003: Peng Jiangnan; Avery Mitchell A; Hamann Mark T
Cyanthiwigin AC and AD, two novel diterpene skeletons from the Jamaican sponge Myrmekioderma styx.
Organic letters 2003;5(24):4575-8.
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2003: Avery Mitchell A; Muraleedharan Kannoth M; Desai Prashant V; Bandyopadhyaya Achintya K; Furtado Marise M; Tekwani Babu L
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
Journal of medicinal chemistry 2003;46(20):4244-58.
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2003: Batra Sanjay; Sabnis Yogesh A; Rosenthal Philip J; Avery Mitchell A
Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines.
Bioorganic & medicinal chemistry 2003;11(10):2293-9.
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2003: Sabnis Yogesh A; Desai Prashant V; Rosenthal Philip J; Avery Mitchell A
Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.
Protein science : a publication of the Protein Society 2003;12(3):501-9.
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2003: Illapakurthy Ashok C; Sabnis Yogesh A; Avery Bonnie A; Avery Mitchell A; Wyandt Christy M
Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solution state: experimental and molecular-modeling studies.
Journal of pharmaceutical sciences 2003;92(3):649-55.
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2003: Minenoa Tomoko; Avery Mitchell A
Giardiasis: recent progress in chemotherapy and drug development.
Current pharmaceutical design 2003;9(11):841-55.
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2002: El Sayed Khalid A; Yousaf Muhammad; Hamann Mark T; Avery Mitchell A; Kelly Michelle; Wipf Peter
Microbial and chemical transformation studies of the bioactive marine sesquiterpenes (S)-(+)-curcuphenol and -curcudiol isolated from a deep reef collection of the Jamaican sponge Didiscus oxeata.
Journal of natural products 2002;65(11):1547-53.
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2002: Lima Patricia C; Avery Mitchell A; Tekwani Babu L; de Alves Helio M; Barreiro Eliezer J; Fraga Carlos A M
Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues.
Farmaco (Società chimica italiana : 1989) 2002;57(10):825-32.
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2002: Mineno T; Stanford K M; Walker L A; Avery M A
Solution-phase parallel synthesis of an isoflavone library for the discovery of novel antigiardial agents.
Combinatorial chemistry & high throughput screening 2002;5(6):481-7.
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2002: Avery Mitchell A; Alvim-Gaston Maria; Vroman Jeffrey A; Wu Baogen; Ager Arba; Peters Wallace; Robinson Brian L; Charman William
Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates.
Journal of medicinal chemistry 2002;45(19):4321-35.
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2002: Jaradat Maisa S; Noonan Daniel J; Wu Baogen; Avery Mitchell A; Feller Dennis R;
Pseudolaric acid analogs as a new class of peroxisome proliferator-activated receptor agonists.
Planta medica 2002;68(8):667-71.
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2002: Sabnis Yogesh; Rosenthal Philip J; Desai Prashant; Avery Mitchell A
Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors.
Journal of biomolecular structure & dynamics 2002;19(5):765-74.
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2002: Avery Mitchell A; Alvim-Gaston Maria; Rodrigues Carlos R; Barreiro Eliezer J; Cohen Fred E; Sabnis Yogesh A; Woolfrey John R
Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies.
Journal of medicinal chemistry 2002;45(2):292-303.
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2002: Vyas Nehal; Avery Bonnie A; Avery Mitchell A; Wyandt Christy M
Carrier-mediated partitioning of artemisinin into Plasmodium falciparum-infected erythrocytes.
Antimicrobial agents and chemotherapy 2002;46(1):105-9.
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2001: Valluri M; Hindupur R M; Bijoy P; Labadie G; Jung J C; Avery M A
Total synthesis of epothilone B.
Organic letters 2001;3(23):3607-9.
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1999: Avery B A; Venkatesh K K; Avery M A
Rapid determination of artemisinin and related analogues using high-performance liquid chromatography and an evaporative light scattering detector.
Journal of chromatography. B, Biomedical sciences and applications 1999;730(1):71-80.
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1999: Vroman J A; Alvim-Gaston M; Avery M A
Current progress in the chemistry, medicinal chemistry and drug design of artemisinin based antimalarials.
Current pharmaceutical design 1999;5(2):101-38.
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1998: Johnson T; Khan I A; Avery M A; Grant J; Meshnick S R
Quantitative structure-activity relationship studies of a series of sulfa drugs as inhibitors of Pneumocystis carinii dihydropteroate synthetase.
Antimicrobial agents and chemotherapy 1998;42(6):1454-8.
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1998: Woolfrey J R; Avery M A; Doweyko A M
Comparison of 3D quantitative structure-activity relationship methods: analysis of the in vitro antimalarial activity of 154 artemisinin analogues by hypothetical active-site lattice and comparative molecular field analysis.
Journal of computer-aided molecular design 1998;12(2):165-81.
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1996: Avery M A; Mehrotra S; Johnson T L; Bonk J D; Vroman J A; Miller R
Structure-activity relationships of the antimalarial agent artemisinin. 5. Analogs of 10-deoxoartemisinin substituted at C-3 and C-9.
Journal of medicinal chemistry 1996;39(21):4149-55.
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1996: Avery M A; Mehrotra S; Bonk J D; Vroman J A; Goins D K; Miller R
Structure-activity relationships of the antimalarial agent artemisinin. 4. Effect of substitution at C-3.
Journal of medicinal chemistry 1996;39(15):2900-6.
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1996: Avery M A; Fan P; Karle J M; Bonk J D; Miller R; Goins D K
Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures.
Journal of medicinal chemistry 1996;39(9):1885-97.
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1995: Avery M A; Bonk J D; Chong W K; Mehrotra S; Miller R; Milhous W; Goins D K; Venkatesan S; Wyandt C; Khan I
Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins.
Journal of medicinal chemistry 1995;38(26):5038-44.
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1993: Avery M A; Gao F; Chong W K; Mehrotra S; Milhous W K
Structure-activity relationships of the antimalarial agent artemisinin. 1. Synthesis and comparative molecular field analysis of C-9 analogs of artemisinin and 10-deoxoartemisinin.
Journal of medicinal chemistry 1993;36(26):4264-75.
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1990: Avery M A; Detre G; Yasuda D; Chao W R; Tanabe M; Crowe D; Peters R; Chong W K
Synthesis and antiinflammatory activity of novel 12 beta-substituted analogues of betamethasone.
Journal of medicinal chemistry 1990;33(7):1852-8.
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1990: Avery M A; Tanabe M; Crowe D F; Detre G; Peters R H; Chong W K
Synthesis and testing of 17a beta-hydroxy-7 alpha-methyl-D-homoestra-4,16-dien-3-one: a highly potent orally active androgen.
Steroids 1990;55(2):59-64.
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1989: Peters R H; Crowe D F; Avery M A; Chong W K; Tanabe M
11 beta-nitrate estrane analogues: potent estrogens.
Journal of medicinal chemistry 1989;32(10):2306-10.
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1989: Peters R H; Crowe D F; Avery M A; Chong W K; Tanabe M
17-Desoxy estrogen analogues.
Journal of medicinal chemistry 1989;32(7):1642-52.
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1988: Peters R H; Crowe D F; Avery M A; Chong W K; Tanabe M
Analogues of [(triethylsilyl)ethynyl]estradiol as potential antifertility agents.
Journal of medicinal chemistry 1988;31(3):572-6.
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1987: Peters R H; Crowe D F; Tanabe M; Avery M A; Chong W K
Steroidal silicon side-chain analogues as potential antifertility agents.
Journal of medicinal chemistry 1987;30(4):646-52.
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