Robert Innis

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Terry Garth E; Liow Jeih-San; Zoghbi Sami S; Hirvonen Jussi; Farris Amanda G; Lerner Alicja; Tauscher Johannes T; Schaus John M; Phebus Lee; Felder Christian C; Morse Cheryl L; Hong Jinsoo S; Pike Victor W; Halldin Christer; Innis Robert B
Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.
Kreisl William C; Mbeo Gilbert; Fujita Masahiro; Zoghbi Sami S; Pike Victor W; Innis Robert B; McArthur Justin C
Stroke incidentally identified using improved positron emission tomography for microglial activation.
Kannan P; John C; Zoghbi S S; Halldin C; Gottesman M M; Innis R B; Hall M D
Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.

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All Publications

2009: Terry Garth E; Liow Jeih-San; Zoghbi Sami S; Hirvonen Jussi; Farris Amanda G; Lerner Alicja; Tauscher Johannes T; Schaus John M; Phebus Lee; Felder Christian C; Morse Cheryl L; Hong Jinsoo S; Pike Victor W; Halldin Christer; Innis Robert B
Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.
NeuroImage 2009;48(2):362-70.
2009: Kreisl William C; Mbeo Gilbert; Fujita Masahiro; Zoghbi Sami S; Pike Victor W; Innis Robert B; McArthur Justin C
Stroke incidentally identified using improved positron emission tomography for microglial activation.
Archives of neurology 2009;66(10):1288-9.
2009: Kannan P; John C; Zoghbi S S; Halldin C; Gottesman M M; Innis R B; Hall M D
Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.
Clinical pharmacology and therapeutics 2009;86(4):368-77.
2009: Fujimura Yota; Zoghbi Sami S; Simèon Fabrice G; Taku Andrew; Pike Victor W; Innis Robert B; Fujita Masahiro
Quantification of translocator protein (18 kDa) in the human brain with PET and a novel radioligand, (18)F-PBR06.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(7):1047-53.
2009: Skinbjerg Mette; Ariano Marjorie A; Thorsell Annika; Heilig Markus; Halldin Christer; Innis Robert B; Sibley David R
Arrestin3 mediates D(2) dopamine receptor internalization.
Synapse (New York, N.Y.) 2009;63(7):621-4.
2009: Fujimura Yota; Yasuno Fumihiko; Farris Amanda; Liow Jeih-San; Geraci Marilla; Drevets Wayne; Pine Daniel S; Ghose Subroto; Lerner Alicja; Hargreaves Richard; Burns H Donald; Morse Cheryl; Pike Victor W; Innis Robert B
Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: positron emission tomographic study with [18F]SPA-RQ.
Biological psychiatry 2009;66(1):94-7.
2009: Skinbjerg Mette; Namkung Yoon; Halldin Christer; Innis Robert B; Sibley David R
Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors.
Synapse (New York, N.Y.) 2009;63(6):462-75.
2009: Seneca Nicholas; Zoghbi Sami S; Liow Jeih-San; Kreisl William; Herscovitch Peter; Jenko Kimberly; Gladding Robert L; Taku Andrew; Pike Victor W; Innis Robert B
Human brain imaging and radiation dosimetry of 11C-N-desmethyl-loperamide, a PET radiotracer to measure the function of P-glycoprotein.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):807-13.
2009: Itoh Tetsuji; Abe Kohji; Zoghbi Sami S; Inoue Osamu; Hong Jinsoo; Imaizumi Masao; Pike Victor W; Innis Robert B; Fujita Masahiro
PET measurement of the in vivo affinity of 11C-(R)-rolipram and the density of its target, phosphodiesterase-4, in the brains of conscious and anesthetized rats.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):749-56.
2009: Tokunaga Masaki; Seneca Nicholas; Shin Ryong-Moon; Maeda Jun; Obayashi Shigeru; Okauchi Takashi; Nagai Yuji; Zhang Ming-Rong; Nakao Ryuji; Ito Hiroshi; Innis Robert B; Halldin Christer; Suzuki Kazutoshi; Higuchi Makoto; Suhara Tetsuya
Neuroimaging and physiological evidence for involvement of glutamatergic transmission in regulation of the striatal dopaminergic system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1887-96.
2009: Briard Emmanuelle; Zoghbi Sami S; Siméon Fabrice G; Imaizumi Masao; Gourley Jonathan P; Shetty H Umesha; Lu Shuiyu; Fujita Masahiro; Innis Robert B; Pike Victor W
Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.
Journal of medicinal chemistry 2009;52(3):688-99.
2009: Liow Jeih-San; Kreisl William; Zoghbi Sami S; Lazarova Neva; Seneca Nicholas; Gladding Robert L; Taku Andrew; Herscovitch Peter; Pike Victor W; Innis Robert B
P-glycoprotein function at the blood-brain barrier imaged using 11C-N-desmethyl-loperamide in monkeys.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(1):108-15.
2009: Finnema Sjoerd J; Donohue Sean R; Zoghbi Sami S; Brown Amira K; Gulyás Balázs; Innis Robert B; Halldin Christer; Pike Victor W
Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo.
Synapse (New York, N.Y.) 2009;63(1):22-30.
2009: Schou Magnus; Zoghbi Sami S; Shetty H Umesha; Shchukin Evgeny; Liow Jeih-San; Hong Jinsoo; Andrée Bengt A; Gulyás Balázs; Farde Lars; Innis Robert B; Pike Victor W; Halldin Christer
Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009;11(1):23-30.
2008: Brown Amira K; Kimura Yasuyuki; Zoghbi Sami S; Siméon Fabrice G; Liow Jeih-San; Kreisl William C; Taku Andrew; Fujita Masahiro; Pike Victor W; Innis Robert B
Metabotropic glutamate subtype 5 receptors are quantified in the human brain with a novel radioligand for PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(12):2042-8.
2008: Shetty H Umesha; Zoghbi Sami S; Siméon Fabrice G; Liow Jeih-San; Brown Amira K; Kannan Pavitra; Innis Robert B; Pike Victor W
Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 receptors with positron emission tomography, occurs by glutathionylation in rat brain.
The Journal of pharmacology and experimental therapeutics 2008;327(3):727-35.
2008: Fujimura Yota; Hwang Paul M; Trout Iii Hugh; Kozloff Louis; Imaizumi Masao; Innis Robert B; Fujita Masahiro
Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195.
Atherosclerosis 2008;201(1):108-11.
2008: Lazarova Neva; Zoghbi Sami S; Hong Jinsoo; Seneca Nicholas; Tuan Ed; Gladding Robert L; Liow Jeih-San; Taku Andrew; Innis Robert B; Pike Victor W
Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.
Journal of medicinal chemistry 2008;51(19):6034-43.
2008: Seneca Nicholas; Zoghbi Sami S; Skinbjerg Mette; Liow Jeih-San; Hong Jinsoo; Sibley David R; Pike Victor W; Halldin Christer; Innis Robert B
Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA.
Synapse (New York, N.Y.) 2008;62(10):756-63.
2008: Seneca Nicholas; Skinbjerg Mette; Zoghbi Sami S; Liow Jeih-San; Gladding Robert L; Hong Jinsoo; Kannan Pavitra; Tuan Edward; Sibley David R; Halldin Christer; Pike Victor W; Innis Robert B
Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand.
Synapse (New York, N.Y.) 2008;62(9):700-9.
2008: van Dyck Christopher H; Avery Robert A; MacAvoy Martha G; Marek Kenneth L; Quinlan Donald M; Baldwin Ronald M; Seibyl John P; Innis Robert B; Arnsten Amy F T
Striatal dopamine transporters correlate with simple reaction time in elderly subjects.
Neurobiology of aging 2008;29(8):1237-46.
2008: Cropley Vanessa L; Fujita Masahiro; Bara-Jimenez William; Brown Amira K; Zhang Xiang-Yang; Sangare Janet; Herscovitch Peter; Pike Victor W; Hallett Mark; Nathan Pradeep J; Innis Robert B
Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPA.
Psychiatry research 2008;163(2):171-82.
2008: Terry Garth; Liow Jeih-San; Chernet Eyassu; Zoghbi Sami S; Phebus Lee; Felder Christian C; Tauscher Johannes; Schaus John M; Pike Victor W; Halldin Christer; Innis Robert B
Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.
NeuroImage 2008;41(3):690-8.
2008: Cropley Vanessa L; Innis Robert B; Nathan Pradeep J; Brown Amira K; Sangare Janet L; Lerner Alicja; Ryu Yong Hoon; Sprague Kelly E; Pike Victor W; Fujita Masahiro
Small effect of dopamine release and no effect of dopamine depletion on [18F]fallypride binding in healthy humans.
Synapse (New York, N.Y.) 2008;62(6):399-408.
2008: Sprague David R; Fujita Masahiro; Ryu Yong Hoon; Liow Jeih-San; Pike Victor W; Innis Robert B
Whole-body biodistribution and radiation dosimetry in monkeys and humans of the phosphodiesterase 4 radioligand [(11)C](R)-rolipram: comparison of two-dimensional planar, bisected and quadrisected image analyses.
Nuclear medicine and biology 2008;35(4):493-500.
2008: Krystal John H; Carter Cameron S; Geschwind Daniel; Manji Husseini K; March John S; Nestler Eric J; Zubieta Jon-Kar; Charney Dennis S; Goldman David; Gur Raquel E; Lieberman Jeffrey A; Roy-Byrne Peter; Rubinow David R; Anderson Stewart A; Barondes Samuel; Berman Karen F; Blair James; Braff David L; Brown E Sherwood; Calabrese Joseph R; Carlezon William A; Cook Edwin H; Davidson Richard J; Davis Michael; Desimone Robert; Drevets Wayne C; Duman Ronald S; Essock Susan M; Faraone Stephen V; Freedman Robert; Friston Karl J; Gelernter Joel; Geller Barbara; Gill Michael; Gould Elizabeth; Grace Anthony A; Grillon Christian; Gueorguieva Ralitza; Hariri Ahmad R; Innis Robert B; Jones Edward G; Kleinman Joel E; Koob George F; Krystal Andrew D; Leibenluft Ellen; Levinson Douglas F; Levitt Pat R; Lewis David A; Liberzon Israel; Lipska Barbara K; Marder Stephen R; Markou Athina; Mason Graeme F; McDougle Christopher J; McEwen Bruce S; McMahon Francis J; Meaney Michael J; Meltzer Herbert Y; Merikangas Kathleen R; Meyer-Lindenberg Andreas; Mirnics Károly; Monteggia Lisa M; Neumeister Alexander; O'Brien Charles P; Owen Michael J; Pine Daniel S; Rapoport Judith L; Rauch Scott L; Robbins Trevor W; Rosenbaum Jerrold F; Rosenberg David R; Ross Christopher A; Rush A John; Sackeim Harold A; Sanacora Gerard; Schatzberg Alan F; Shaham Yavin; Siever Larry J; Sunderland Trey; Tecott Laurence H; Thase Michael E; Todd Richard D; Weissman Myrna M; Yehuda Rachel; Yoshikawa Takeo; Young Elizabeth A; McCandless R
It is time to take a stand for medical research and against terrorism targeting medical scientists.
Biological psychiatry 2008;63(8):725-7.
2008: Zoghbi Sami S; Liow Jeih-San; Yasuno Fumihiko; Hong Jinsoo; Tuan Edward; Lazarova Neva; Gladding Robert L; Pike Victor W; Innis Robert B
11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(4):649-56.
2008: Fujita Masahiro; Imaizumi Masao; Zoghbi Sami S; Fujimura Yota; Farris Amanda G; Suhara Tetsuya; Hong Jinsoo; Pike Victor W; Innis Robert B
Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.
NeuroImage 2008;40(1):43-52.
2008: Imaizumi Masao; Briard Emmanuelle; Zoghbi Sami S; Gourley Jonathan P; Hong Jinsoo; Fujimura Yota; Pike Victor W; Innis Robert B; Fujita Masahiro
Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors.
NeuroImage 2008;39(3):1289-98.
2008: Bois Frederic; Baldwin Ronald M; Amici Louis; Al-Tikriti Mohammed S; Kula Nora; Baldessarini Ross; Innis Robert B; Staley Julie K; Tamagnan Gilles D
Synthesis, radiolabeling and baboon SPECT imaging of 2beta-carbomethoxy-3beta-(3'-[(123)I]iodophenyl)tropane ([(123)I]YP256) as a serotonin transporter radiotracer.
Nuclear medicine and biology 2008;35(1):53-9.
2008: Cai Lisheng; Liow Jeih-San; Zoghbi Sami S; Cuevas Jessica; Baetas Cesar; Hong Jinsoo; Shetty H Umesha; Seneca Nicholas M; Brown Amira K; Gladding Robert; Temme Sebastian S; Herman Mary M; Innis Robert B; Pike Victor W
Synthesis and evaluation of N-methyl and S-methyl 11C-labeled 6-methylthio-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as radioligands for imaging beta-amyloid plaques in Alzheimer's disease.
Journal of medicinal chemistry 2008;51(1):148-58.
2008: Briard Emmanuelle; Zoghbi Sami S; Imaizumi Masao; Gourley Jonathan P; Shetty H Umesha; Hong Jinsoo; Cropley Vanessa; Fujita Masahiro; Innis Robert B; Pike Victor W
Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.
Journal of medicinal chemistry 2008;51(1):17-30.
2008: Yasuno Fumihiko; Brown Amira K; Zoghbi Sami S; Krushinski Joseph H; Chernet Eyassu; Tauscher Johannes; Schaus John M; Phebus Lee A; Chesterfield Amy K; Felder Christian C; Gladding Robert L; Hong Jinsoo; Halldin Christer; Pike Victor W; Innis Robert B
The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(2):259-69.
2007: Brown Amira K; Fujita Masahiro; Fujimura Yota; Liow Jeih-San; Stabin Michael; Ryu Yong H; Imaizumi Masao; Hong Jinsoo; Pike Victor W; Innis Robert B
Radiation dosimetry and biodistribution in monkey and man of 11C-PBR28: a PET radioligand to image inflammation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(12):2072-9.
2007: McCarron Julie A; Zoghbi Sami S; Shetty H Umesha; Vermeulen Eric S; Wikström Håkan V; Ichise Masanori; Yasuno Fumihiko; Halldin Christer; Innis Robert B; Pike Victor W
Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
European journal of nuclear medicine and molecular imaging 2007;34(10):1670-82.
2007: Cai Lisheng; Cuevas Jessica; Temme Sebastian; Herman Mary M; Dagostin Claudio; Widdowson David A; Innis Robert B; Pike Victor W
Synthesis and structure-affinity relationships of new 4-(6-iodo-H-imidazo[1,2-a]pyridin-2-yl)-N-dimethylbenzeneamine derivatives as ligands for human beta-amyloid plaques.
Journal of medicinal chemistry 2007;50(19):4746-58.
2007: Innis Robert B; Cunningham Vincent J; Delforge Jacques; Fujita Masahiro; Gjedde Albert; Gunn Roger N; Holden James; Houle Sylvain; Huang Sung-Cheng; Ichise Masanori; Iida Hidehiro; Ito Hiroshi; Kimura Yuichi; Koeppe Robert A; Knudsen Gitte M; Knuuti Juhani; Lammertsma Adriaan A; Laruelle Marc; Logan Jean; Maguire Ralph Paul; Mintun Mark A; Morris Evan D; Parsey Ramin; Price Julie C; Slifstein Mark; Sossi Vesna; Suhara Tetsuya; Votaw John R; Wong Dean F; Carson Richard E
Consensus nomenclature for in vivo imaging of reversibly binding radioligands.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(9):1533-9.
2007: Seneca Nicholas; Cai Lisheng; Liow Jeih-San; Zoghbi Sami S; Gladding Robert L; Hong Jinsoo; Pike Victor W; Innis Robert B
Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques.
Nuclear medicine and biology 2007;34(6):681-9.
2007: Innis Robert B; Carson Richard
Consensus nomenclature: its time has come.
European journal of nuclear medicine and molecular imaging 2007;34(8):1239.
2007: Imaizumi Masao; Briard Emmanuelle; Zoghbi Sami S; Gourley Jonathan P; Hong Jinsoo; Musachio John L; Gladding Robert; Pike Victor W; Innis Robert B; Fujita Masahiro
Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain.
Synapse (New York, N.Y.) 2007;61(8):595-605.
2007: Ryu Yong Hoon; Liow Jeih-San; Zoghbi Sami; Fujita Masahiro; Collins Jerry; Tipre Dnyanesh; Sangare Janet; Hong Jinsoo; Pike Victor W; Innis Robert B
Disulfiram inhibits defluorination of (18)F-FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT1A receptors in human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(7):1154-61.
2007: Siméon Fabrice G; Brown Amira K; Zoghbi Sami S; Patterson Velvet M; Innis Robert B; Pike Victor W
Synthesis and simple 18F-labeling of 3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a high affinity radioligand for imaging monkey brain metabotropic glutamate subtype-5 receptors with positron emission tomography.
Journal of medicinal chemistry 2007;50(14):3256-66.
2007: Zhang Xiang-Yang; Yasuno Fumihiko; Zoghbi Sami S; Liow Jeih-San; Hong Jinsoo; McCarron Julie A; Pike Victor W; Innis Robert B
Quantification of serotonin 5-HT1A receptors in humans with [11C](R)-(-)-RWAY: radiometabolite(s) likely confound brain measurements.
Synapse (New York, N.Y.) 2007;61(7):469-77.
2007: Shetty H Umesha; Zoghbi Sami S; Liow Jeih-San; Ichise Masanori; Hong Jinsoo; Musachio John L; Halldin Christer; Seidel Jurgen; Innis Robert B; Pike Victor W
Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I.
European journal of nuclear medicine and molecular imaging 2007;34(5):667-78.
2007: Yasuno Fumihiko; Sanabria Sandra M; Burns Donald; Hargreaves Richard J; Ghose Subroto; Ichise Masanori; Chin Frederick T; Morse Cheryl L; Pike Victor W; Innis Robert B
PET imaging of neurokinin-1 receptors with [(18)F]SPA-RQ in human subjects: assessment of reference tissue models and their test-retest reproducibility.
Synapse (New York, N.Y.) 2007;61(4):242-51.
2007: Rodríguez-Gómez Jose A; Lu Jian-Qiang; Velasco Iván; Rivera Seth; Zoghbi Sami S; Liow Jeih-San; Musachio John L; Chin Frederick T; Toyama Hiroshi; Seidel Jurgen; Green Michael V; Thanos Panayotis K; Ichise Masanori; Pike Victor W; Innis Robert B; McKay Ron D G
Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease.
Stem cells (Dayton, Ohio) 2007;25(4):918-28.
2007: Liow Jeih-San; Lu Shuiyu; McCarron Julie A; Hong Jinsoo; Musachio John L; Pike Victor W; Innis Robert B; Zoghbi Sami S
Effect of a P-glycoprotein inhibitor, Cyclosporin A, on the disposition in rodent brain and blood of the 5-HT1A receptor radioligand, [11C](R)-(-)-RWAY.
Synapse (New York, N.Y.) 2007;61(2):96-105.
2007: Fujita Masahiro; Imaizumi Masao; D'Sa Carrol; Zoghbi Sami S; Crescenzo Matthew S; Hong Jinsoo; Musachio John L; Gee Antony D; Seidel Jurgen; Green Michael V; Pike Victor W; Duman Ronald S; Innis Robert B
In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration.
Synapse (New York, N.Y.) 2007;61(2):78-86.
2007: Brown Amira K; George David T; Fujita Masahiro; Liow Jeih-San; Ichise Masanori; Hibbeln Joseph; Ghose Subroto; Sangare Janet; Hommer Daniel; Innis Robert B
PET [11C]DASB imaging of serotonin transporters in patients with alcoholism.
Alcoholism, clinical and experimental research 2007;31(1):28-32.
2007: Sprague David R; Chin Frederick T; Liow Jeih-San; Fujita Masahiro; Burns H Donald; Hargreaves Richard; Stubbs James B; Pike Victor W; Innis Robert B; Mozley P David
Human biodistribution and radiation dosimetry of the tachykinin NK1 antagonist radioligand [18F]SPA-RQ: comparison of thin-slice, bisected, and 2-dimensional planar image analysis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(1):100-7.
2007: Imaizumi Masao; Kim Hyun-Ju; Zoghbi Sami S; Briard Emmanuelle; Hong Jinsoo; Musachio John L; Ruetzler Christl; Chuang De-Maw; Pike Victor W; Innis Robert B; Fujita Masahiro
PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat.
Neuroscience letters 2007;411(3):200-5.
2007: Cai Lisheng; Innis Robert B; Pike Victor W
Radioligand development for PET imaging of beta-amyloid (Abeta)--current status.
Current medicinal chemistry 2007;14(1):19-52.
2006: Yasuno Fumihiko; Zoghbi Sami S; McCarron Julie A; Hong Jinsoo; Ichise Masanori; Brown Amira K; Gladding Robert L; Bacher John D; Pike Victor W; Innis Robert B
Quantification of serotonin 5-HT1A receptors in monkey brain with [11C](R)-(-)-RWAY.
Synapse (New York, N.Y.) 2006;60(7):510-20.
2006: Bois Frederic; Baldwin Ronald M; Kula Nora S; Baldessarini Ross J; Al Tikriti M; Innis Robert B; Tamagnan Gilles D
Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine.
Bioorganic & medicinal chemistry letters 2006;16(19):5222-5.
2006: Seneca Nicholas; Gulyás Balázs; Varrone Andrea; Schou Magnus; Airaksinen Anu; Tauscher Johannes; Vandenhende Francois; Kielbasa William; Farde Lars; Innis Robert B; Halldin Christer
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.
Psychopharmacology 2006;188(1):119-27.
2006: Musachio John L; Hong Jinsoo; Ichise Masanori; Seneca Nicholas; Brown Amira K; Liow Jeih-San; Halldin Christer; Innis Robert B; Pike Victor W; He Rong; Zhou Jia; Kozikowski Alan P
Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(12):3101-4.
2006: Baldwin Ronald M; Zoghbi Sami S; Staley Julie K; Brenner Eric; Al-Tikriti Mohammed S; Amici Louis; Fujita Masahiro; Innis Robert B; Tamagnan Gilles
Chemical fate of the nicotinic acetylcholinergic radiotracer [123I]5-IA-85380 in baboon brain and plasma.
Nuclear medicine and biology 2006;33(4):549-54.
2006: Cropley Vanessa L; Fujita Masahiro; Innis Robert B; Nathan Pradeep J
Molecular imaging of the dopaminergic system and its association with human cognitive function.
Biological psychiatry 2006;59(10):898-907.
2006: Nichols Lisa; Pike Victor W; Cai Lisheng; Innis Robert B
Imaging and in vivo quantitation of beta-amyloid: an exemplary biomarker for Alzheimer's disease?
Biological psychiatry 2006;59(10):940-7.
2006: Ichise Masanori; Vines Douglass C; Gura Tami; Anderson George M; Suomi Stephen J; Higley J Dee; Innis Robert B
Effects of early life stress on [11C]DASB positron emission tomography imaging of serotonin transporters in adolescent peer- and mother-reared rhesus monkeys.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(17):4638-43.
2006: Seneca Nicholas; Finnema Sjoerd J; Farde Lars; Gulyás Balázs; Wikström Håkan V; Halldin Christer; Innis Robert B
Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.
Synapse (New York, N.Y.) 2006;59(5):260-9.
2006: Zoghbi Sami S; Shetty H Umesha; Ichise Masanori; Fujita Masahiro; Imaizumi Masao; Liow Jeih-San; Shah Jay; Musachio John L; Pike Victor W; Innis Robert B
PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(3):520-7.
2006: Tipre Dnyanesh N; Zoghbi Sami S; Liow Jeih-San; Green Michael V; Seidel Jurgen; Ichise Masanori; Innis Robert B; Pike Victor W
PET imaging of brain 5-HT1A receptors in rat in vivo with 18F-FCWAY and improvement by successful inhibition of radioligand defluorination with miconazole.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(2):345-53.
2006: Kim Jae Seung; Ichise Masanori; Sangare Janet; Innis Robert B
PET imaging of serotonin transporters with [11C]DASB: test-retest reproducibility using a multilinear reference tissue parametric imaging method.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(2):208-14.
2006: Cropley Vanessa L; Fujita Masahiro; Musachio John L; Hong Jinsoo; Ghose Subroto; Sangare Janet; Nathan Pradeep J; Pike Victor W; Innis Robert B
Whole-body biodistribution and estimation of radiation-absorbed doses of the dopamine D1 receptor radioligand 11C-NNC 112 in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(1):100-4.
2006: Fujita Masahiro; Ichise Masanori; Zoghbi Sami S; Liow Jeih-San; Ghose Subroto; Vines Douglass C; Sangare Janet; Lu Jian-Qiang; Cropley Vanessa L; Iida Hidehiro; Kim Kyeong Min; Cohen Robert M; Bara-Jimenez William; Ravina Bernard; Innis Robert B
Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease.
Annals of neurology 2006;59(1):174-7.
2006: Tamagnan Gilles; Alagille David; Fu Xing; Kula Nora S; Baldessarini Ross J; Innis Robert B; Baldwin Ronald M
Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes.
Bioorganic & medicinal chemistry letters 2006;16(1):217-20.
2006: Staley Julie K; Sanacora Gerard; Tamagnan Gilles; Maciejewski Paul K; Malison Robert T; Berman Robert M; Vythilingam Meena; Kugaya Akira; Baldwin Ronald M; Seibyl John P; Charney Dennis; Innis Robert B
Sex differences in diencephalon serotonin transporter availability in major depression.
Biological psychiatry 2006;59(1):40-7.
2005: Li Shizhe; Chen Zhengguang; Zhang Yan; Lizak Martin; Bacher John; Innis Robert B; Shen Jun
In vivo single-shot, proton-localized 13C MRS of rhesus monkey brain.
NMR in biomedicine 2005;18(8):560-9.
2005: Best Susan E; Sarrel Philip M; Malison Robert T; Laruelle Marc; Zoghbi Sami S; Baldwin Ronald M; Seibyl John P; Innis Robert B; van Dyck Christopher H
Striatal dopamine transporter availability with [123I]beta-CIT SPECT is unrelated to gender or menstrual cycle.
Psychopharmacology 2005;183(2):181-9.
2005: Schou Magnus; Halldin Christer; Pike Victor W; Mozley P David; Dobson David; Innis Robert B; Farde Lars; Hall Håkan
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(5):517-20.
2005: Staley Julie K; Gottschalk Christopher; Petrakis Ismene L; Gueorguieva Ralitza; O'Malley Stephanie; Baldwin Ronald; Jatlow Peter; Verhoeff Nicolaas Paul L G; Perry Edward; Weinzimmer David; Frohlich Erin; Ruff Elizabeth; van Dyck Christopher H; Seibyl John P; Innis Robert B; Krystal John H
Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking.
Archives of general psychiatry 2005;62(8):877-88.
2005: Seneca Nicholas; Andree Bengt; Sjoholm Nils; Schou Magnus; Pauli Stefan; Mozley P David; Stubbs James B; Liow Jeih-San; Sovago Judit; Gulyás Balazs; Innis Robert; Halldin Christer
Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates.
Nuclear medicine communications 2005;26(8):695-700.
2005: Fujita Masahiro; Zoghbi Sami S; Crescenzo Matthew S; Hong Jinsoo; Musachio John L; Lu Jian-Qiang; Liow Jeih-San; Seneca Nicholas; Tipre Dnyanesh N; Cropley Vanessa L; Imaizumi Masao; Gee Antony D; Seidel Jurgen; Green Michael V; Pike Victor W; Innis Robert B
Quantification of brain phosphodiesterase 4 in rat with (R)-[11C]Rolipram-PET.
NeuroImage 2005;26(4):1201-10.
2005: Finnema Sjoerd J; Seneca Nicholas; Farde Lars; Shchukin Evgeny; Sóvágó Judit; Gulyás Balázs; Wikström Håkan V; Innis Robert B; Neumeyer John L; Halldin Christer
A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey.
Nuclear medicine and biology 2005;32(4):353-60.
2005: van Dyck Christopher H; Malison Robert T; Jacobsen Leslie K; Seibyl John P; Staley Julie K; Laruelle Marc; Baldwin Ronald M; Innis Robert B; Gelernter Joel
Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(5):745-51.
2005: Toyama Hiroshi; Ye Daniel; Ichise Masanori; Liow Jeih-San; Cai Lisheng; Jacobowitz David; Musachio John L; Hong Jinsoo; Crescenzo Mathew; Tipre Dnyanesh; Lu Jian-Qiang; Zoghbi Sami; Vines Douglass C; Seidel Jurgen; Katada Kazuhiro; Green Michael V; Pike Victor W; Cohen Robert M; Innis Robert B
PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2005;32(5):593-600.
2005: Ghose Subroto; Fujita Masahiro; Morrison Paul; Uhl George; Murphy Dennis L; Mozley P David; Schou Magnus; Halldin Christer; Innis Robert
Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters.
Synapse (New York, N.Y.) 2005;56(2):100-4.
2005: Tamagnan Gilles; Alagille David; Fu Xing; Kula Nora S; Baldessarini Ross J; Innis Robert B; Baldwin Ronald M
Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.
Bioorganic & medicinal chemistry letters 2005;15(4):1131-3.
2005: Ravina B; Eidelberg D; Ahlskog J E; Albin R L; Brooks D J; Carbon M; Dhawan V; Feigin A; Fahn S; Guttman M; Gwinn-Hardy K; McFarland H; Innis R; Katz R G; Kieburtz K; Kish S J; Lange N; Langston J W; Marek K; Morin L; Moy C; Murphy D; Oertel W H; Oliver G; Palesch Y; Powers W; Seibyl J; Sethi K D; Shults C W; Sheehy P; Stoessl A J; Holloway R
The role of radiotracer imaging in Parkinson disease.
Neurology 2005;64(2):208-15.
2004: Kugaya Akira; Sanacora Gerard; Staley Julie K; Malison Robert T; Bozkurt Ali; Khan Shaukat; Anand Amit; Van Dyck Christopher H; Baldwin Ronald M; Seibyl John P; Charney Dennis; Innis Robert B
Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
Biological psychiatry 2004;56(7):497-502.
2004: Lu Jian-Qiang; Ichise Masanori; Liow Jeih-San; Ghose Subroto; Vines Doug; Innis Robert B
Biodistribution and radiation dosimetry of the serotonin transporter ligand 11C-DASB determined from human whole-body PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(9):1555-9.
2004: Toyama Hiroshi; Ichise Masanori; Liow Jeih-San; Modell Kendra J; Vines Douglass C; Esaki Takanori; Cook Michelle; Seidel Jurgen; Sokoloff Louis; Green Michael V; Innis Robert B
Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(8):1398-405.
2004: Schou Magnus; Halldin Christer; Sóvágó Judit; Pike Victor W; Hall Håkan; Gulyás Balázs; Mozley P David; Dobson David; Shchukin E; Innis Robert B; Farde Lars
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain.
Synapse (New York, N.Y.) 2004;53(2):57-67.
2004: Fujita Masahiro; Southwick Steven M; Denucci Christopher C; Zoghbi Sami S; Dillon Martha S; Baldwin Ronald M; Bozkurt Ali; Kugaya Akira; Verhoeff N Paul L G; Seibyl John P; Innis Robert B
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.
Biological psychiatry 2004;56(2):95-100.
2004: Tipre Dnyanesh N; Fujita Masahiro; Chin Frederick T; Seneca Nicholas; Vines Douglas; Liow Jeih-San; Pike Victor W; Innis Robert B
Whole-body biodistribution and radiation dosimetry estimates for the PET dopamine transporter probe 18F-FECNT in non-human primates.
Nuclear medicine communications 2004;25(7):737-42.
2004: Bois Frederic; Baldwin Ronald M; Kula Nora S; Baldessarini Ross J; Innis Robert B; Tamagnan Gilles
Synthesis and monoamine transporter affinity of 3'-analogs of 2-beta-carbomethoxy-3-beta-(4'-iodophenyl)tropane (beta-CIT).
Bioorganic & medicinal chemistry letters 2004;14(9):2117-20.
2004: Fujita Masahiro; Varrone Andrea; Kim Kyeong Min; Watabe Hiroshi; Zoghbi Sami S; Seneca Nicholas; Tipre Dnyanesh; Seibyl John P; Innis Robert B; Iida Hidehiro
Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D2 receptors using [123I]epidepride SPET.
European journal of nuclear medicine and molecular imaging 2004;31(5):644-54.
2004: Cai Lisheng; Chin Frederick T; Pike Victor W; Toyama Hiroshi; Liow Jeih-San; Zoghbi Sami S; Modell Kendra; Briard Emmanuelle; Shetty H Umesha; Sinclair Kathryn; Donohue Sean; Tipre Dnyanesh; Kung Mei-Ping; Dagostin Claudio; Widdowson David A; Green Michael; Gao Weiyi; Herman Mary M; Ichise Masanori; Innis Robert B
Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease.
Journal of medicinal chemistry 2004;47(9):2208-18.
2004: van Dyck Christopher H; Malison Robert T; Staley Julie K; Jacobsen Leslie K; Seibyl John P; Laruelle Marc; Baldwin Ronald M; Innis Robert B; Gelernter Joel
Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype.
The American journal of psychiatry 2004;161(3):525-31.
2004: Toyama Hiroshi; Ichise Masanori; Liow Jeih-San; Vines Douglass C; Seneca Nicholas M; Modell Kendra J; Seidel Jurgen; Green Michael V; Innis Robert B
Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET.
Nuclear medicine and biology 2004;31(2):251-6.
2004: Li Qian; Ma Li; Innis Robert B; Seneca Nicholas; Ichise Masanori; Huang Henry; Laruelle Marc; Murphy Dennis L
Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB).
The Journal of pharmacology and experimental therapeutics 2004;308(2):481-6.
2004: Tipre D N; Lu J Q; Fujita M; Ichise M; Vines D; Innis R B
Radiation dosimetry estimates for the PET serotonin transporter probe 11C-DASB determined from whole-body imaging in non-human primates.
Nuclear medicine communications 2004;25(1):81-6.
2003: Abi-Dargham Anissa; Kegeles Lawrence S; Martinez Diana; Innis Robert B; Laruelle Marc
Dopamine mediation of positive reinforcing effects of amphetamine in stimulant naïve healthy volunteers: results from a large cohort.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(6):459-68.
2003: Fujita Masahiro; Ichise Masanori; van Dyck Christopher H; Zoghbi Sami S; Tamagnan Gilles; Mukhin Alexey G; Bozkurt Ali; Seneca Nicholas; Tipre Dnyanesh; DeNucci Christopher C; Iida Hidehiro; Vaupel D Bruce; Horti Andrew G; Koren Andrei O; Kimes Alane S; London Edythe D; Seibyl John P; Baldwin Ronald M; Innis Robert B
Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET.
European journal of nuclear medicine and molecular imaging 2003;30(12):1620-9.
2003: Baldwin Ronald M; Fu Xing; Kula Nora S; Baldessarini Ross J; Amici Louis; Innis Robert B; Tamagnan Gilles D
Synthesis and affinity of a possible byproduct of electrophilic radiolabeling of [123I]IBZM.
Bioorganic & medicinal chemistry letters 2003;13(22):4015-7.
2003: Kugaya Akira; Sanacora Gerard; Verhoeff Nicolaas P L G; Fujita Masahiro; Mason Graeme F; Seneca Nicholas M; Bozkurt Ali; Khan Shaukat A; Anand Amit; Degen Kathleen; Charney Dennis S; Zoghbi Sami S; Baldwin Ronald M; Seibyl John P; Innis Robert B
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.
Biological psychiatry 2003;54(8):792-9.
2003: Schou Magnus; Halldin Christer; Sóvágó Judit; Pike Victor W; Gulyás Balázs; Mozley P David; Johnson David P; Hall Håkan; Innis Robert B; Farde Lars
Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER.
Nuclear medicine and biology 2003;30(7):707-14.
2003: Ichise Masanori; Liow Jeih-San; Lu Jian-Qiang; Takano Akihiro; Model Kendra; Toyama Hiroshi; Suhara Tetsuya; Suzuki Kazutoshi; Innis Robert B; Carson Richard E
Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(9):1096-112.
2003: Vines Douglass C; Ichise Masanori; Liow Jeih-San; Toyama Hiroshi; Innis Robert B
Evaluation of 2 scatter correction methods using a striatal phantom for quantitative brain SPECT.
Journal of nuclear medicine technology 2003;31(3):157-60.
2003: Kugaya Akira; Epperson C Neill; Zoghbi Sami; van Dyck Christopher H; Hou Yankun; Fujita Masahiro; Staley Julie K; Garg Pradeep K; Seibyl John P; Innis Robert B
Increase in prefrontal cortex serotonin 2A receptors following estrogen treatment in postmenopausal women.
The American journal of psychiatry 2003;160(8):1522-4.
2003: Fujita Masahiro; Al-Tikriti Mohammed S; Tamagnan Gilles; Zoghbi Sami S; Bozkurt Ali; Baldwin Ronald M; Innis Robert B
Influence of acetylcholine levels on the binding of a SPECT nicotinic acetylcholine receptor ligand [123I]5-I-A-85380.
Synapse (New York, N.Y.) 2003;48(3):116-22.
2003: Kim Kyeong Min; Varrone Andrea; Watabe Hiroshi; Shidahara Miho; Fujita Masahiro; Innis Robert B; Iida Hidehiro
Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(4):512-9.
2003: Kugaya Akira; Seneca Nicholas M; Snyder Peter J; Williams Stephen A; Malison Robert T; Baldwin Ronald M; Seibyl John P; Innis Robert B
Changes in human in vivo serotonin and dopamine transporter availabilities during chronic antidepressant administration.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(2):413-20.
2002: Ichise Masanori; Toyama Hiroshi; Innis Robert B; Carson Richard E
Strategies to improve neuroreceptor parameter estimation by linear regression analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(10):1271-81.
2002: Ogier Lionel; Turpin Frédéric; Baldwin Ronald M; Riché Françoise; Law Ho; Innis Robert B; Tamagnan Gilles
Rearrangement of a mesylate tropane intermediate in nucleophilic substitution reactions. Synthesis of aza-bicyclo[3.2.1]octane and aza-bicyclo[3.2.2]nonane ethers, imides, and amines.
The Journal of organic chemistry 2002;67(11):3637-42.
2002: Fu Xing; Tan Ping-Zhong; Kula Nora S; Baldessarini Ross; Tamagnan Gilles; Innis Robert B; Baldwin Ronald M
Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2A ligands for PET or SPECT brain imaging.
Journal of medicinal chemistry 2002;45(11):2319-24.
2002: Emond Patrick; Vercouillie Johnny; Innis Robert; Chalon Sylvie; Mavel Sylvie; Frangin Yves; Halldin Christer; Besnard Jean-Claude; Guilloteau Denis
Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.
Journal of medicinal chemistry 2002;45(6):1253-8.
2002: Fujita Masahiro; Seibyl John P; Vaupel D Bruce; Tamagnan Gilles; Early Michele; Zoghbi Sami S; Baldwin Ronald M; Horti Andrew G; KoreN Andrei O; Mukhin Alexey G; Khan Shaukat; Bozkurt Ali; Kimes Alane S; London Edythe D; Innis Robert B
Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects.
European journal of nuclear medicine and molecular imaging 2002;29(2):183-90.
2002: van Dyck Christopher H; Quinlan Donald M; Cretella Lisa M; Staley Julie K; Malison Robert T; Baldwin Ronald M; Seibyl John P; Innis Robert B
Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder.
The American journal of psychiatry 2002;159(2):309-12.
2002: Cesati Richard R; Tamagnan Gilles; Baldwin Ronald M; Zoghbi Sami S; Innis Robert B; Kula Nora S; Baldessarini Ross J; Katzenellenbogen John A
Synthesis of cyclopentadienyltricarbonyl rhenium phenyltropanes by double ligand transfer: organometallic ligands for the dopamine transporter.
Bioconjugate chemistry 2002;13(1):29-39.
2002: van Dyck Christopher H; Seibyl John P; Malison Robert T; Laruelle Marc; Zoghbi Sami S; Baldwin Ronald M; Innis Robert B
Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002;10(1):36-43.
2001: Marek K; Innis R; van Dyck C; Fussell B; Early M; Eberly S; Oakes D; Seibyl J
[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression.
Neurology 2001;57(11):2089-94.
2001: Varrone A; Marek K L; Jennings D; Innis R B; Seibyl J P
[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2001;16(6):1023-32.
2001: Staley J K; Krishnan-Sarin S; Zoghbi S; Tamagnan G; Fujita M; Seibyl J P; Maciejewski P K; O'Malley S; Innis R B
Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers.
Synapse (New York, N.Y.) 2001;41(4):275-84.
2001: Martinez D; Gelernter J; Abi-Dargham A; van Dyck C H; Kegeles L; Innis R B; Laruelle M
The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(5):553-60.
2001: Staley J K; Van Dyck C H; Tan P Z; Al Tikriti M; Ramsby Q; Klump H; Ng C; Garg P; Soufer R; Baldwin R M; Innis R B
Comparison of [(18)F]altanserin and [(18)F]deuteroaltanserin for PET imaging of serotonin(2A) receptors in baboon brain: pharmacological studies.
Nuclear medicine and biology 2001;28(3):271-9.
2001: Soares J C; van Dyck C H; Tan P; Zoghbi S S; Garg P; Soufer R; Baldwin R M; Fujita M; Staley J K; Fu X; Amici L; Seibyl J; Innis R B
Reproducibility of in vivo brain measures of 5-HT2A receptors with PET and.
Psychiatry research 2001;106(2):81-93.
2001: Goldstein S; Friedman J H; Innis R; Seibyl J; Marek K
Hemi-parkinsonism due to a midbrain arteriovenous malformation: dopamine transporter imaging.
Movement disorders : official journal of the Movement Disorder Society 2001;16(2):350-3.
2001: Zoghbi S S; Tamagnan G; Baldwin M F; Al-Tikriti M S; Amici L; Seibyl J P; Innis R B
Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates.
Nuclear medicine and biology 2001;28(1):91-6.
2000: van Dyck C H; Soares J C; Tan P Z; Staley J K; Baldwin R M; Amici L A; Fu X; Garg P K; Seibyl J P; Charney D S; Innis R B
Equilibrium modeling of 5-HT(2A) receptors with [18F]deuteroaltanserin and PET: feasibility of a constant infusion paradigm.
Nuclear medicine and biology 2000;27(8):715-22.
2000: Fujita M; Charney D S; Innis R B
Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations.
Biological psychiatry 2000;48(8):801-12.
2000: Jacobsen L K; Staley J K; Zoghbi S S; Seibyl J P; Kosten T R; Innis R B; Gelernter J
Prediction of dopamine transporter binding availability by genotype: a preliminary report.
The American journal of psychiatry 2000;157(10):1700-3.
2000: Fujita M; Tamagnan G; Zoghbi S S; Al-Tikriti M S; Baldwin R M; Seibyl J P; Innis R B
Measurement of alpha4beta2 nicotinic acetylcholine receptors with [123I]5-I-A-85380 SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(9):1552-60.
2000: Staley J K; Tamagnan G; Baldwin R M; Fujita M; Al Tikriti M S; Eshima L; Thornback J; Roe D; Lu L; Seibyl J P; Innis R B
SPECT imaging with the D(4) receptor antagonist L-750,667 in nonhuman primate brain.
Nuclear medicine and biology 2000;27(6):547-56.
2000: Tamagnan G; Baldwin R M; Kula N S; Baldessarini R J; Innis R B
Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(2''-, 3''- or 4''-substituted) biphenyltropanes.
Bioorganic & medicinal chemistry letters 2000;10(16):1783-5.
2000: Varrone A; Fujita M; Verhoeff N P; Zoghbi S S; Baldwin R M; Rajeevan N; Charney D S; Seibyl J P; Innis R B
Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(8):1343-51.
2000: van Dyck C H; Malison R T; Seibyl J P; Laruelle M; Klumpp H; Zoghbi S S; Baldwin R M; Innis R B
Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT.
Neurobiology of aging 2000;21(4):497-501.
2000: Jacobsen L K; Staley J K; Malison R T; Zoghbi S S; Seibyl J P; Kosten T R; Innis R B
Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients.
The American journal of psychiatry 2000;157(7):1134-40.
2000: Bremner J D; Innis R B; Southwick S M; Staib L; Zoghbi S; Charney D S
Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder.
The American journal of psychiatry 2000;157(7):1120-6.
2000: Anand A; Verhoeff P; Seneca N; Zoghbi S S; Seibyl J P; Charney D S; Innis R B
Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients.
The American journal of psychiatry 2000;157(7):1108-14.
2000: Tamagnan G; Baldwin R M; Kula N S; Baldessarini R J; Innis R B
Cyclopentadienyltricarbonylrheniumbenzazepines: synthesis and binding affinity.
Bioorganic & medicinal chemistry letters 2000;10(10):1113-5.
2000: Laruelle M; Abi-Dargham A; van Dyck C; Gil R; D'Souza D C; Krystal J; Seibyl J; Baldwin R; Innis R
Dopamine and serotonin transporters in patients with schizophrenia: an imaging study with [(123)I]beta-CIT.
Biological psychiatry 2000;47(5):371-9.
2000: Mukhin A G; Gündisch D; Horti A G; Koren A O; Tamagnan G; Kimes A S; Chambers J; Vaupel D B; King S L; Picciotto M R; Innis R B; London E D
5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.
Molecular pharmacology 2000;57(3):642-9.
2000: Kugaya A; Fujita M; Innis R B
Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders.
Annals of nuclear medicine 2000;14(1):1-9.
2000: van Dyck C H; Tan P Z; Baldwin R M; Amici L A; Garg P K; Ng C K; Soufer R; Charney D S; Innis R B
PET quantification of 5-HT2A receptors in the human brain: a constant infusion paradigm with [18F]altanserin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(2):234-41.
2000: Scanley B E; Gandelman M S; Laruelle M; Al-Tikriti M S; Baldwin R M; Zoghbi S S; Hoffer P B; Wang S; Neumeyer J L; Innis R B
[123I]IPCIT and [123I]beta-CIT as SPECT tracers for the dopamine transporter: a comparative analysis in nonhuman primates.
Nuclear medicine and biology 2000;27(1):13-21.
2000: Bremner J D; Innis R B; White T; Fujita M; Silbersweig D; Goddard A W; Staib L; Stern E; Cappiello A; Woods S; Baldwin R; Charney D S
SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder.
Biological psychiatry 2000;47(2):96-106.
2000: Fujita M; Verhoeff N P; Varrone A; Zoghbi S S; Baldwin R M; Jatlow P A; Anderson G M; Seibyl J P; Innis R B
Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans.
European journal of pharmacology 2000;387(2):179-88.
2000: Castner S A; al-Tikriti M S; Baldwin R M; Seibyl J P; Innis R B; Goldman-Rakic P S
Behavioral changes and [123I]IBZM equilibrium SPECT measurement of amphetamine-induced dopamine release in rhesus monkeys exposed to subchronic amphetamine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(1):4-13.
2000: Fujita M; Innis R B
Nuclear psychiatry: specialty for the twenty-first century?
European journal of nuclear medicine 2000;27(1 Suppl):S39-42.
1999: Fujita M; Seibyl J P; Verhoeff N P; Ichise M; Baldwin R M; Zoghbi S S; Burger C; Staley J K; Rajeevan N; Charney D S; Innis R B
Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors.
Synapse (New York, N.Y.) 1999;34(4):290-304.
1999: Ichise M; Fujita M; Seibyl J P; Verhoeff N P; Baldwin R M; Zoghbi S S; Rajeevan N; Charney D S; Innis R B
Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(11):1902-12.
1999: Verhoeff N P; Soares J C; D'Souza C D; Gil R; Degen K; Abi-Dargham A; Zoghbi S S; Fujita M; Rajeevan N; Seibyl J P; Krystal J H; van Dyck C H; Charney D S; Innis R B
[123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia.
Psychiatry research 1999;91(3):163-73.
1999: Verhoeff N P; Petroff O A; Hyder F; Zoghbi S S; Fujita M; Rajeevan N; Rothman D L; Seibyl J P; Mattson R H; Innis R B
Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS.
Epilepsia 1999;40(10):1433-8.
1999: Soares J C; Innis R B
Neurochemical brain imaging investigations of schizophrenia.
Biological psychiatry 1999;46(5):600-15.
1999: Tan P Z; Baldwin R M; Van Dyck C H; Al-Tikriti M; Roth B; Khan N; Charney D S; Innis R B
Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent.
Nuclear medicine and biology 1999;26(6):601-8.
1999: Bremner J D; Baldwin R; Horti A; Staib L H; Ng C K; Tan P Z; Zea-Ponce Y; Zoghbi S; Seibyl J P; Soufer R; Charney D S; Innis R B
Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects.
Psychiatry research 1999;91(2):79-91.
1999: Laruelle M; Abi-Dargham A; Gil R; Kegeles L; Innis R
Increased dopamine transmission in schizophrenia: relationship to illness phases.
Biological psychiatry 1999;46(1):56-72.
1999: Charney D S; Innis R B; Nestler E J; Davis K L; Nemeroff C B; Weinberger D R
Increasing public trust and confidence in psychiatric research.
Biological psychiatry 1999;46(1):1-2.
1999: Abi-Dargham A; Laruelle M; Krystal J; D'Souza C; Zoghbi S; Baldwin R M; Seibyl J; Mawlawi O; de Erasquin G; Charney D; Innis R B
No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(6):650-61.
1999: Innis R B; Marek K L; Sheff K; Zoghbi S; Castronuovo J; Feigin A; Seibyl J P
Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT.
Movement disorders : official journal of the Movement Disorder Society 1999;14(3):436-42.
1999: Tan P Z; Baldwin R M; Soufer R; Garg P K; Charney D S; Innis R B
A complete remote-control system for reliable preparation of [18F]altanserin.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1999;50(5):923-7.
1999: Fujita M; Woods S W; Verhoeff N P; Abi-Dargham A; Baldwin R M; Zoghbi S S; Soares J C; Jatlow P A; Krystal J H; Rajeevan N; Charney D S; Seibyl J P; Innis R B
Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans.
European journal of pharmacology 1999;368(2-3):161-72.
1998: Kennan R P; Scanley B E; Innis R B; Gore J C
Physiological basis for BOLD MR signal changes due to neuronal stimulation: separation of blood volume and magnetic susceptibility effects.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1998;40(6):840-6.
1998: Malison R T; Price L H; Berman R; van Dyck C H; Pelton G H; Carpenter L; Sanacora G; Owens M J; Nemeroff C B; Rajeevan N; Baldwin R M; Seibyl J P; Innis R B; Charney D S
Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography.
Biological psychiatry 1998;44(11):1090-8.
1998: Abi-Dargham A; Krystal J H; Anjilvel S; Scanley B E; Zoghbi S; Baldwin R M; Rajeevan N; Ellis S; Petrakis I L; Seibyl J P; Charney D S; Laruelle M; Innis R B
Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil.
The American journal of psychiatry 1998;155(11):1550-5.
1998: Staley J K; Malison R T; Innis R B
Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression.
Biological psychiatry 1998;44(7):534-49.
1998: Rajeevan N; Zubal I G; Ramsby S Q; Zoghbi S S; Seibyl J; Innis R B
Significance of nonuniform attenuation correction in quantitative brain SPECT imaging.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(10):1719-26.
1998: Malison R T; Innis R B; Laruelle M
RE: Logan et al., 1997.
Synapse (New York, N.Y.) 1998;30(2):236-7.
1998: Seibyl J P; Marek K; Sheff K; Zoghbi S; Baldwin R M; Charney D S; van Dyck C H; Innis R B
Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(9):1500-8.
1998: Malison R T; McCance E; Carpenter L L; Baldwin R M; Seibyl J P; Price L H; Kosten T R; Innis R B
[123I]beta-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts.
Psychopharmacology 1998;137(4):321-5.
1998: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; Redmond D E; Innis R B; Zea-Ponce Y; Roth R H
Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study.
Brain research 1998;795(1-2):55-62.
1998: Malison R T; Best S E; van Dyck C H; McCance E F; Wallace E A; Laruelle M; Baldwin R M; Seibyl J P; Price L H; Kosten T R; Innis R B
Elevated striatal dopamine transporters during acute cocaine abstinence as measured by [123I] beta-CIT SPECT.
The American journal of psychiatry 1998;155(6):832-4.
1998: Abi-Dargham A; Gil R; Krystal J; Baldwin R M; Seibyl J P; Bowers M; van Dyck C H; Charney D S; Innis R B; Laruelle M
Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort.
The American journal of psychiatry 1998;155(6):761-7.
1998: Laruelle M; Gelernter J; Innis R B
D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene.
Molecular psychiatry 1998;3(3):261-5.
1998: Innis R B
Single photon emission computed tomography imaging of dopaminergic function: presynaptic transporter, postsynaptic receptor, and "intrasynaptic" transmitter.
Advances in pharmacology (San Diego, Calif.) 1998;42():215-9.
1997: Abi-Dargham A; Innis R B; Wisniewski G; Baldwin R M; Neumeyer J L; Seibyl J P
Human biodistribution and dosimetry of iodine-123-fluoroalkyl analogs of beta-CIT.
European journal of nuclear medicine 1997;24(11):1422-5.
1997: Seibyl J P; Marek K; Sheff K; Baldwin R M; Zoghbi S; Zea-Ponce Y; Charney D S; van Dyck C H; Hoffer P B; Innis R B
Test/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(9):1453-9.
1997: Laruelle M; D'Souza C D; Baldwin R M; Abi-Dargham A; Kanes S J; Fingado C L; Seibyl J P; Zoghbi S S; Bowers M B; Jatlow P; Charney D S; Innis R B
Imaging D2 receptor occupancy by endogenous dopamine in humans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(3):162-74.
1997: Scanley B E; Kennan R P; Cannan S; Skudlarski P; Innis R B; Gore J C
Functional magnetic resonance imaging of median nerve stimulation in rats at 2.0 T.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;37(6):969-72.
1997: Zea-Ponce Y; Baldwin R M; Stratton M D; al-Tikriti M; Soufer R; Schaus J M; Innis R B
Radiosynthesis and PET imaging of [N-methyl-11C]LY257327 as a tracer for 5-HT transporters.
Nuclear medicine and biology 1997;24(3):251-4.
1997: Bremner J D; Innis R B; Salomon R M; Staib L H; Ng C K; Miller H L; Bronen R A; Krystal J H; Duncan J; Rich D; Price L H; Malison R; Dey H; Soufer R; Charney D S
Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse.
Archives of general psychiatry 1997;54(4):364-74.
1997: Abi-Dargham A; Zea-Ponce Y; Terriere D; al-Tikriti M; Baldwin R M; Hoffer P; Charney D; Leysen J E; Laruelle M; Mertens J; Innis R B
Preclinical evaluation of [123I]R93274 as a SPECT radiotracer for imaging 5-HT2A receptors.
European journal of pharmacology 1997;321(3):285-93.
1997: Bremner J D; Innis R B; Ng C K; Staib L H; Salomon R M; Bronen R A; Duncan J; Southwick S M; Krystal J H; Rich D; Zubal G; Dey H; Soufer R; Charney D S
Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder.
Archives of general psychiatry 1997;54(3):246-54.
1997: Bremner J D; Randall P; Vermetten E; Staib L; Bronen R A; Mazure C; Capelli S; McCarthy G; Innis R B; Charney D S
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report.
Biological psychiatry 1997;41(1):23-32.
1997: Laruelle M; Iyer R N; al-Tikriti M S; Zea-Ponce Y; Malison R; Zoghbi S S; Baldwin R M; Kung H F; Charney D S; Hoffer P B; Innis R B; Bradberry C W
Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates.
Synapse (New York, N.Y.) 1997;25(1):1-14.
1996: Laruelle M; Innis R B
Images in neuroscience. SPECT imaging of synaptic dopamine.
The American journal of psychiatry 1996;153(10):1249.
1996: Seibyl J P; Marek K; Innis R B
Images in neuroscience. Neuroimaging, XII. SPECT imaging of dopamine nerve terminals.
The American journal of psychiatry 1996;153(9):1131.
1996: Laruelle M; Abi-Dargham A; van Dyck C H; Gil R; D'Souza C D; Erdos J; McCance E; Rosenblatt W; Fingado C; Zoghbi S S; Baldwin R M; Seibyl J P; Krystal J H; Charney D S; Innis R B
Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9235-40.
1996: Abi-Dargham A; Gandelman M S; DeErausquin G A; Zea-Ponce Y; Zoghbi S S; Baldwin R M; Laruelle M; Charney D S; Hoffer P B; Neumeyer J L; Innis R B
SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of beta-CIT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(7):1129-33.
1996: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; al-Tikriti M S; Zea-Ponce Y; Innis R B; Redmond D E; Roth R H
Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys.
Cell transplantation 1996;5(2):315-25.
1996: Seibyl J P; Laruelle M; van Dyck C H; Wallace E; Baldwin R M; Zoghbi S; Zea-Ponce Y; Neumeyer J L; Charney D S; Hoffer P B; Innis R B
Reproducibility of iodine-123-beta-CIT SPECT brain measurement of dopamine transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):222-8.
1996: van Dyck C H; Seibyl J P; Stubbs J B; Zoghbi S; Wisniewski G; Baldwin R M; Zea-Ponce Y; Charney D S; Hoffer P B; Innis R B
Human biodistribution and dosimetry of the SPECT D2 dopamine receptor radioligand [123I]IBF.
Nuclear medicine and biology 1996;23(1):9-16.
1996: Seibyl J P; Zea-Ponce Y; Brenner L; Baldwin R M; Krystal J H; Offord S J; Mochoviak S; Charney D S; Hoffer P B; Innis R B
Continuous intravenous infusion of iodine-123-IBZM for SPECT determination of human brain dopamine receptor occupancy by antipsychotic agent RWJ-37796.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(1):11-5.
1995: Malison R T; McDougle C J; van Dyck C H; Scahill L; Baldwin R M; Seibyl J P; Price L H; Leckman J F; Innis R B
[123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder.
The American journal of psychiatry 1995;152(9):1359-61.
1995: Bremner J D; Randall P; Scott T M; Bronen R A; Seibyl J P; Southwick S M; Delaney R C; McCarthy G; Charney D S; Innis R B
MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder.
The American journal of psychiatry 1995;152(7):973-81.
1995: Zea-Ponce Y; Baldwin R M; Laruelle M; Wang S; Neumeyer J L; Innis R B
Simplified multidose preparation of iodine-123-beta-CIT: a marker for dopamine transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(3):525-9.
1995: Abi-Dargham A; Gandelman M; Zoghbi S S; Laruelle M; Baldwin R M; Randall P; Zea-Ponce Y; Charney D S; Hoffer P B; Innis R B
Reproducibility of SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(2):167-75.
1994: Laruelle M; Wallace E; Seibyl J P; Baldwin R M; Zea-Ponce Y; Zoghbi S S; Neumeyer J L; Charney D S; Hoffer P B; Innis R B
Graphical, kinetic, and equilibrium analyses of in vivo [123I] beta-CIT binding to dopamine transporters in healthy human subjects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):982-94.
1994: Laruelle M; al-Tikriti M S; Zea-Ponce Y; Zoghbi S S; Baldwin R M; Charney D S; Hoffer P B; Kung H F; Innis R B
In vivo quantification of dopamine D2 receptor parameters in nonhuman primates with [123I]iodobenzofuran and single photon emission computerized tomography.
European journal of pharmacology 1994;263(1-2):39-51.
1994: Gandelman M S; Baldwin R M; Zoghbi S S; Zea-Ponce Y; Innis R B
Evaluation of ultrafiltration for the free-fraction determination of single photon emission computed tomography (SPECT) radiotracers: beta-CIT, IBF, and iomazenil.
Journal of pharmaceutical sciences 1994;83(7):1014-9.
1994: Neumeyer J L; Wang S; Gao Y; Milius R A; Kula N S; Campbell A; Baldessarini R J; Zea-Ponce Y; Baldwin R M; Innis R B
N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters.
Journal of medicinal chemistry 1994;37(11):1558-61.
1994: Laruelle M; van Dyck C; Abi-Dargham A; Zea-Ponce Y; Zoghbi S S; Charney D S; Baldwin R M; Hoffer P B; Kung H F; Innis R B
Compartmental modeling of iodine-123-iodobenzofuran binding to dopamine D2 receptors in healthy subjects.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(5):743-54.
1994: Laruelle M; Abi-Dargham A; al-Tikriti M S; Baldwin R M; Zea-Ponce Y; Zoghbi S S; Charney D S; Hoffer P B; Innis R B
SPECT quantification of [123I]iomazenil binding to benzodiazepine receptors in nonhuman primates: II. Equilibrium analysis of constant infusion experiments and correlation with in vitro parameters.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(3):453-65.
1994: Elsworth J D; al-Tikriti M S; Sladek J R; Taylor J R; Innis R B; Redmond D E; Roth R H
Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function.
Experimental neurology 1994;126(2):300-4.
1994: al-Tikriti M S; Dey H M; Zoghbi S S; Baldwin R M; Zea-Ponce Y; Innis R B
Dual-isotope autoradiographic measurement of regional blood flow and benzodiazepine receptor availability following unilateral middle cerebral artery occlusion.
European journal of nuclear medicine 1994;21(3):196-202.
1994: Laruelle M; Giddings S S; Zea-Ponce Y; Charney D S; Neumeyer J L; Baldwin R M; Innis R B
Methyl 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylate in vitro binding to dopamine and serotonin transporters under "physiological" conditions.
Journal of neurochemistry 1994;62(3):978-86.
1994: Zea-Ponce Y; Baldwin R M; Zoghbi S S; Innis R B
Formation of 1-[123I]iodobutane in labeling [123I]iomazenil by iododestannylation: implications for the reaction mechanism.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1994;45(1):63-8.
1994: Innis R B
Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease.
European journal of nuclear medicine 1994;21(1):1-5.
1994: Kontur P J; al-Tikriti M; Innis R B; Roth R H
Postmortem stability of monoamines, their metabolites, and receptor binding in rat brain regions.
Journal of neurochemistry 1994;62(1):282-90.
1994: Laruelle M; Baldwin R M; Innis R B
SPECT imaging of dopamine and serotonin transporters in nonhuman primate brain.
NIDA research monograph 1994;138():131-59.
1993: Innis R B; Seibyl J P; Scanley B E; Laruelle M; Abi-Dargham A; Wallace E; Baldwin R M; Zea-Ponce Y; Zoghbi S; Wang S
Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11965-9.
1993: Malison R T; Miller E G; Greene R; McCarthy G; Charney D S; Innis R B
Computer-assisted coregistration of multislice SPECT and MR brain images by fixed external fiducials.
Journal of computer assisted tomography 1993;17(6):952-60.
1993: Bremner J D; Scott T M; Delaney R C; Southwick S M; Mason J W; Johnson D R; Innis R B; McCarthy G; Charney D S
Deficits in short-term memory in posttraumatic stress disorder.
The American journal of psychiatry 1993;150(7):1015-9.
1993: Wang S; Gao Y; Laruelle M; Baldwin R M; Scanley B E; Innis R B; Neumeyer J L
Enantioselectivity of cocaine recognition sites: binding of (1S)- and (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane (beta-CIT) to monoamine transporters.
Journal of medicinal chemistry 1993;36(13):1914-7.
1993: Wall S C; Innis R B; Rudnick G
Binding of the cocaine analog 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane to serotonin and dopamine transporters: different ionic requirements for substrate and 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane binding.
Molecular pharmacology 1993;43(2):264-70.
1992: Innis R B
Neuroreceptor imaging with SPECT.
The Journal of clinical psychiatry 1992;53 Suppl():29-34.
1992: Sybirska E; al-Tikriti M; Zoghbi S S; Baldwin R M; Johnson E W; Innis R B
SPECT imaging of the benzodiazepine receptor: autoradiographic comparison of receptor density and radioligand distribution.
Synapse (New York, N.Y.) 1992;12(2):119-28.
1992: Innis R B; Malison R T; al-Tikriti M; Hoffer P B; Sybirska E H; Seibyl J P; Zoghbi S S; Baldwin R M; Laruelle M; Smith E O
Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates.
Synapse (New York, N.Y.) 1992;10(3):177-84.
1992: al-Tikriti M S; Roth R H; Kessler R M; Innis R B
Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions.
Brain research 1992;575(1):39-46.
1991: Innis R B; al-Tikriti M S; Zoghbi S S; Baldwin R M; Sybirska E H; Laruelle M A; Malison R T; Seibyl J P; Zimmermann R C; Johnson E W
SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(9):1754-61.
1991: Innis R; Baldwin R; Sybirska E; Zea Y; Laruelle M; al-Tikriti M; Charney D; Zoghbi S; Smith E; Wisniewski G
Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT.
European journal of pharmacology 1991;200(2-3):369-70.
1991: Deutch A Y; Moghaddam B; Innis R B; Krystal J H; Aghajanian G K; Bunney B S; Charney D S
Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia.
Schizophrenia research 1991;4(2):121-56.
1991: Innis R; Zoghbi S; Johnson E; Woods S; al-Tikriti M; Baldwin R; Seibyl J; Malison R; Zubal G; Charney D
SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154.
European journal of pharmacology 1991;193(2):249-52.
1991: Kessler R M; Ansari M S; Schmidt D E; de Paulis T; Clanton J A; Innis R; al-Tikriti M; Manning R G; Gillespie D
High affinity dopamine D2 receptor radioligands. 2. [125I]epidepride, a potent and specific radioligand for the characterization of striatal and extrastriatal dopamine D2 receptors.
Life sciences 1991;49(8):617-28.
1991: Johnson E W; Sybirska E; al-Tikriti M; Innis R B
Calibration of [123I]iodine-labeled tissue standards for autoradiographic studies.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(12):1199-201.
1990: Kritzer M F; Innis R B; Goldman-Rakic P S
Regional distribution of cholecystokinin binding sites in macaque basal ganglia determined by in vitro receptor autoradiography.
Neuroscience 1990;38(1):81-92.
1990: Johnson E W; Woods S W; Zoghbi S; McBride B J; Baldwin R M; Innis R B
Receptor binding characterization of the benzodiazepine radioligand 125I-Ro16-0154: potential probe for SPECT brain imaging.
Life sciences 1990;47(17):1535-46.
1989: Lidow M S; Goldman-Rakic P S; Rakic P; Innis R B
Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6412-6.
1989: Charney D S; Innis R B; Duman R S; Woods S W; Heninger G R
Platelet alpha-2-receptor binding and adenylate cyclase activity in panic disorder.
Psychopharmacology 1989;98(1):102-7.
1988: Kritzer M F; Innis R B; Goldman-Rakic P S
Regional distribution of cholecystokinin receptors in macaque medial temporal lobe determined by in vitro receptor autoradiography.
The Journal of comparative neurology 1988;276(2):219-30.
1988: Innis R B; Nestler E J; Aghajanian G K
Evidence for G protein mediation of serotonin- and GABAB-induced hyperpolarization of rat dorsal raphe neurons.
Brain research 1988;459(1):27-36.
1987: Innis R B; Aghajanian G K
Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons.
European journal of pharmacology 1987;143(2):195-204.
1987: Kritzer M F; Innis R B; Goldman-Rakic P S
Regional distribution of cholecystokinin receptors in primate cerebral cortex determined by in vitro receptor autoradiography.
The Journal of comparative neurology 1987;263(3):418-35.
1987: Innis R B; Charney D S; Heninger G R
Differential 3H-imipramine platelet binding in patients with panic disorder and depression.
Psychiatry research 1987;21(1):33-41.
1987: Innis R B; Aghajanian G K
Pertussis toxin blocks autoreceptor-mediated inhibition of dopaminergic neurons in rat substantia nigra.
Brain research 1987;411(1):139-43.
1986: Innis R B; Bunney B S; Charney D S; Price L H; Glazer W M; Sternberg D E; Rubin A L; Heninger G R
Does the cholecystokinin antagonist proglumide possess antipsychotic activity?
Psychiatry research 1986;18(1):1-7.
1986: Innis R B; Aghajanian G K
Cholecystokinin-containing and nociceptive neurons in rat Edinger-Westphal nucleus.
Brain research 1986;363(2):230-8.
1985: Innis R B; Andrade R; Aghajanian G K
Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra.
Brain research 1985;335(2):381-3.
1985: Innis R B; Aghajanian G K
Integrated anatomical and physiological studies of neuronal cholecystokinin receptors.
Annals of the New York Academy of Sciences 1985;448():188-97.
1983: Zarbin M A; Innis R B; Wamsley J K; Snyder S H; Kuhar M J
Autoradiographic localization of cholecystokinin receptors in rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(4):877-906.
1981: Correa F M; Innis R B; Hester L D; Snyder S H
Diffuse enkephalin innervation from caudate to globus pallidus.
Neuroscience letters 1981;25(1):63-8.
1981: Zarbin M A; Wamsley J K; Innis R B; Kuhar M J
Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve.
Life sciences 1981;29(7):697-705.
1981: Zarbin M A; Innis R B; Wamsley J K; Snyder S H; Kuhar M J
Autoradiographic localization of CCK receptors in guinea pig brain.
European journal of pharmacology 1981;71(2-3):349-50.
1981: Innis R B; Manning D C; Stewart J M; Snyder S H
[3H]Bradykinin receptor binding in mammalian tissue membranes.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2630-4.
1981: Snyder S H; Bruns R F; Daly J W; Innis R B
Multiple neurotransmitter receptors in the brain: amines, adenosine, and cholecystokinin.
Federation proceedings 1981;40(2):142-6.
1980: Innis R B; Snyder S H
Distinct cholecystokinin receptors in brain and pancreas.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6917-21.
1980: Innis R B; Synder S H
Cholecystokinin receptor binding in brain and pancreas: regulation of pancreatic binding by cyclic and acyclic guanine nucleotides.
European journal of pharmacology 1980;65(1):123-4.
1980: Innis R B; Snyder S H
Neuroleptic radioreceptor assay and evaluation of a tricyclic antidepressant assay using [3H]-imipramine.
Psychopharmacology bulletin 1980;16(3):80-2.
1980: Corrêa F M; Innis R B; Rouot B; Pasternak G W; Snyder S H
Fluorescent probes of alpha- and beta-adrenergic and opiate receptors: biochemical and histochemical evaluation.
Neuroscience letters 1980;16(1):47-53.
1979: Innis R B; Tune L; Rock R; Depaulo R; U'Prichard D C; Snyder S H
Tricyclic antidepressant radioreceptor assay.
European journal of pharmacology 1979;58(4):473-7.
1979: Innis R B; Correa F M; Synder S H
Carazolol, an extremely potent beta-adrenergic blocker: binding to beta-receptors in brain membranes.
Life sciences 1979;24(24):2255-64.
1979: Freedberg K A; Innis R B; Creese I; Snyder S H
Antischizophrenic drugs: differential plasma protein binding and therapeutic activity.
Life sciences 1979;24(26):2467-73.
1979: Corrêa F M; Innis R B; Uhl G R; Snyder S H
Bradykinin-like immunoreactive neuronal systems localized histochemically in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(3):1489-93.
1979: Innis R B; Corrêa F M; Uhl G R; Schneider B; Snyder S H
Cholecystokinin octapeptide-like immunoreactivity: histochemical localization in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):521-5.
1979: Snyder S H; Innis R B
Peptide neurotransmitters.
Annual review of biochemistry 1979;48():755-82.
1978: Innis R B; Bylund D B; Snyder S H
A simple, sensitive and specific radioreceptor assay for beta-adrenergic antagonist drugs.
Life sciences 1978;23(20):2031-7.

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Robert Innis

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