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Kuniyo Inouye

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Co-Publications
Name
37
Sakaki, Toshiyuki
18
Ohta, Miho
18
Tonomura, Ben'ichiro
15
Yasukawa, Kiyoshi
15
Takita, Teisuke
14
Oneda, Hiroshi
13
Shinkyo, Raku
9
Kamakura, Masaki
8
Sawada, Natsumi
7
Kusudo, Tatsuya
6
Kato, Shigeaki
6
Fushiki, Tohru
6
Hashida, Yasuhiko
6
Ikushiro, Shin-ichi
6
Kusano, Masayuki

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Publications

TOP 3
Narita Yusaku; Inouye Kuniyo
Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas alpha-amylase isozymes I and II.
Miyake Yuka; Yasumoto Makoto; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
Activation of a membrane-bound serine protease matriptase on the cell surface.
Kojima Kenji; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
Role of the stem domain of matriptase in the interaction with its physiological inhibitor, hepatocyte growth factor activator inhibitor type I.

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All Publications

2009: Narita Yusaku; Inouye Kuniyo
Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas alpha-amylase isozymes I and II.
Journal of agricultural and food chemistry 2009;57(19):9218-25.
2009: Miyake Yuka; Yasumoto Makoto; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
Activation of a membrane-bound serine protease matriptase on the cell surface.
Journal of biochemistry 2009;146(2):273-82.
2009: Kojima Kenji; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
Role of the stem domain of matriptase in the interaction with its physiological inhibitor, hepatocyte growth factor activator inhibitor type I.
Journal of biochemistry 2009;145(6):783-90.
2009: Sakurama Haruko; Takita Teisuke; Mikami Bunzo; Itoh Takafumi; Yasukawa Kiyoshi; Inouye Kuniyo
Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate.
Journal of biochemistry 2009;145(5):555-63.
2009: Murai Nobuhito; Miyake Yuka; Tsuzuki Satoshi; Inouye Kuniyo; Fushiki Tohru
Involvement of the cytoplasmic juxtamembrane region of matriptase in its exclusive localization to the basolateral membrane domain of Madin-Darby canine kidney epithelial cells.
Cytotechnology 2009;59(3):169-76.
2009: Yasukawa Kiyoshi; Mizuno Masaki; Inouye Kuniyo
Characterization of Moloney murine leukaemia virus/avian myeloblastosis virus chimeric reverse transcriptases.
Journal of biochemistry 2009;145(3):315-24.
2009: Kojima Kenji; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
The activity of a type II transmembrane serine protease, matriptase, is dependent solely on the catalytic domain.
Bioscience, biotechnology, and biochemistry 2009;73(2):454-6.
2009: Inouye Kuniyo; Nakano Kimio; Asaoka Kohei; Yasukawa Kiyoshi
Effects of thermal treatment on the coagulation of soy proteins induced by subtilisin Carlsberg.
Journal of agricultural and food chemistry 2009;57(2):717-23.
2008: Ueda Mitsuhiro; Noda Kanako; Nakazawa Masami; Miyatake Kazutaka; Ohki Satoshi; Sakaguchi Minoru; Inouye Kuniyo
A novel anti-plant viral protein from coelomic fluid of the earthworm Eisenia foetida: purification, characterization and its identification as a serine protease.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2008;151(4):381-5.
2008: Saruwatari Yoshihiro; Wada Takumi; Takita Teisuke; Inouye Kuniyo
Substrate-induced conformational changes of the truncated catalytic domain of Geobacillus stearothermophilus lysyl-tRNA synthetase as examined by fluorescence.
Biochimica et biophysica acta 2008;1784(11):1633-40.
2008: Ueda Mitsuhiro; Asano Tomohiko; Nakazawa Masami; Miyatake Kazutaka; Inouye Kuniyo
Purification and characterization of novel raw-starch-digesting and cold-adapted alpha-amylases from Eisenia foetida.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2008;150(1):125-30.
2008: Takita Teisuke; Aono Takahiro; Sakurama Haruko; Itoh Takafumi; Wada Takumi; Minoda Masashi; Yasukawa Kiyoshi; Inouye Kuniyo
Effects of introducing negative charges into the molecular surface of thermolysin by site-directed mutagenesis on its activity and stability.
Biochimica et biophysica acta 2008;1784(3):481-8.
2008: Kojima Kenji; Tsuzuki Satoshi; Fushiki Tohru; Inouye Kuniyo
Roles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptase.
The Journal of biological chemistry 2008;283(5):2478-87.
2008: Yasukawa Kiyoshi; Nemoto Daisuke; Inouye Kuniyo
Comparison of the thermal stabilities of reverse transcriptases from avian myeloblastosis virus and Moloney murine leukaemia virus.
Journal of biochemistry 2008;143(2):261-8.
2008: Okumura Shiro; Saitoh Hiroyuki; Ishikawa Tomoyuki; Mizuki Eiichi; Inouye Kuniyo
Identification and characterization of a novel cytotoxic protein, parasporin-4, produced by Bacillus thuringiensis A1470 strain.
Biotechnology annual review 2008;14():225-52.
2007: Yasukawa Kiyoshi; Inouye Kuniyo
Improving the activity and stability of thermolysin by site-directed mutagenesis.
Biochimica et biophysica acta 2007;1774(10):1281-8.
2007: Inouye Kuniyo; Shimada Takashi; Yasukawa Kiyoshi
Effects of neutral salts and alcohols on the activity of Streptomyces caespitosus neutral protease.
Journal of biochemistry 2007;142(3):317-24.
2007: Inouye Kuniyo; Nakamura Koji; Kusano Masayuki; Yasukawa Kiyoshi
Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length.
Bioscience, biotechnology, and biochemistry 2007;71(8):2083-6.
2007: Yasukawa Kiyoshi; Kusano Masayuki; Inouye Kuniyo
A new method for the extracellular production of recombinant thermolysin by co-expressing the mature sequence and pro-sequence in Escherichia coli.
Protein engineering, design & selection : PEDS 2007;20(8):375-83.
2007: Inouye Kuniyo; Shimada Takashi; Yasukawa Kiyoshi
Purification to homogeneity of a neutral metalloproteinase from Streptomyces caespitosus.
Bioscience, biotechnology, and biochemistry 2007;71(7):1773-6.
2007: Tatsumi Chika; Hashida Yasuhiko; Yasukawa Kiyoshi; Inouye Kuniyo
Effects of site-directed mutagenesis of the surface residues Gln128 and Gln225 of thermolysin on its catalytic activity.
Journal of biochemistry 2007;141(6):835-42.
2007: Hashida Yasuhiko; Inouye Kuniyo
Kinetic analysis of the activation-and-inhibition dual effects of cobalt ion on thermolysin activity.
Journal of biochemistry 2007;141(6):843-53.
2007: Hashida Yasuhiko; Inouye Kuniyo
Molecular mechanism of the inhibitory effect of cobalt ion on thermolysin activity and the suppressive effect of calcium ion on the cobalt ion-dependent inactivation of thermolysin.
Journal of biochemistry 2007;141(6):879-88.
2007: Sawada Natsumi; Yamamoto Keiko; Yamada Sachiko; Ikushiro Shinichi; Kamakura Masaki; Ohta Miho; Inouye Kuniyo; Sakaki Toshiyuki
Role of Gln 85 of human CYP27A1 in 25-hydroxyvitamin D(3)-binding and protein folding.
Biochemical and biophysical research communications 2007;355(1):211-6.
2007: Inouye Kuniyo; Kusano Masayuki; Hashida Yasuhiko; Minoda Masashi; Yasukawa Kiyoshi
Engineering, expression, purification, and production of recombinant thermolysin.
Biotechnology annual review 2007;13():43-64.
2006: Kakita Hirotaka; Kamishima Hiroshi; Inouye Kuniyo
Uronic acid determination by high performance liquid chromatography with postcolumn fluorescence derivatization.
Journal of chromatography. A 2006;1129(2):296-9.
2006: Shinkyo Raku; Kamakura Masaki; Ikushiro Shin-ichi; Inouye Kuniyo; Sakaki Toshiyuki
Biodegradation of dioxins by recombinant Escherichia coli expressing rat CYP1A1 or its mutant.
Applied microbiology and biotechnology 2006;72(3):584-90.
2006: Hamamoto Hiromi; Kusudo Tatsuya; Urushino Naoko; Masuno Hiroyuki; Yamamoto Keiko; Yamada Sachiko; Kamakura Masaki; Ohta Miho; Inouye Kuniyo; Sakaki Toshiyuki
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats.
Molecular pharmacology 2006;70(1):120-8.
2006: Morimoto Koichi; Furuta Erino; Hashimoto Hiroshi; Inouye Kuniyo
Effects of high concentration of salts on the esterase activity and structure of a kiwifruit peptidase, actinidain.
Journal of biochemistry 2006;139(6):1065-71.
2006: Kusano Masayuki; Yasukawa Kiyoshi; Hashida Yasuhiko; Inouye Kuniyo
Engineering of the pH-dependence of thermolysin activity as examined by site-directed mutagenesis of Asn112 located at the active site of thermolysin.
Journal of biochemistry 2006;139(6):1017-23.
2006: Lee Seunjae; Mouri Yoshiki; Minoda Masashi; Oneda Hiroshi; Inouye Kuniyo
Comparison of the wild-type alpha-amylase and its variant enzymes in Bacillus amyloliquefaciens in activity and thermal stability, and insights into engineering the thermal stability of bacillus alpha-amylase.
Journal of biochemistry 2006;139(6):1007-15.
2006: Lee Seunjae; Oneda Hiroshi; Minoda Masashi; Tanaka Akiyoshi; Inouye Kuniyo
Comparison of starch hydrolysis activity and thermal stability of two Bacillus licheniformis alpha-amylases and insights into engineering alpha-amylase variants active under acidic conditions.
Journal of biochemistry 2006;139(6):997-1005.
2006: Yoshioka Hidenori; Kasai Noriyuki; Ikushiro Shinichi; Shinkyo Raku; Kamakura Masaki; Ohta Miho; Inouye Kuniyo; Sakaki Toshiyuki
Enzymatic properties of human CYP2W1 expressed in Escherichia coli.
Biochemical and biophysical research communications 2006;345(1):169-74.
2006: Okumura Shiro; Saitoh Hiroyuki; Wasano Naoya; Katayama Hideki; Higuchi Kazuhiko; Mizuki Eiichi; Inouye Kuniyo
Efficient solubilization, activation, and purification of recombinant Cry45Aa of Bacillus thuringiensis expressed as inclusion bodies in Escherichia coli.
Protein expression and purification 2006;47(1):144-51.
2006: Urushino Naoko; Yamamoto Keiko; Kagawa Norio; Ikushiro Shinichi; Kamakura Masaki; Yamada Sachiko; Kato Shigeaki; Inouye Kuniyo; Sakaki Toshiyuki
Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1.
Biochemistry 2006;45(14):4405-12.
2006: Yasukawa Kiyoshi; Kusano Masayuki; Nakamura Koji; Inouye Kuniyo
Characterization of Gly-D-Phe, Gly-L-Leu, and D-Phe as affinity ligands to thermolysin.
Protein expression and purification 2006;46(2):332-6.
2006: Inouye Kuniyo; Minoda Masashi; Takita Teisuke; Sakurama Haruko; Hashida Yasuhiko; Kusano Masayuki; Yasukawa Kiyoshi
Extracellular production of recombinant thermolysin expressed in Escherichia coli, and its purification and enzymatic characterization.
Protein expression and purification 2006;46(2):248-55.
2006: Lee Hee-Seob; Kim Jin-Soo; Shim Kyuho; Kim Jung-Woo; Inouye Kuniyo; Oneda Hiroshi; Kim Young-Wan; Cheong Kyung-Ah; Cha Hyunju; Woo Eui-Jeon; Auh Joong Hyuck; Lee Sung-Joon; Kim Jung-Wan; Park Kwan-Hwa
Dissociation/association properties of a dodecameric cyclomaltodextrinase. Effects of pH and salt concentration on the oligomeric state.
The FEBS journal 2006;273(1):109-21.
2005: Orihara Kanami; Yamazaki Takashi; Shinkyo Raku; Sakaki Toshiyuki; Inouye Kuniyo; Tsukamoto Akira; Sugiura Jun; Shishido Kazuo
Rat cytochrome P450-mediated transformation of dichlorodibenzo-p-dioxins by recombinant white-rot basidiomycete Coriolus hirsutus.
Applied microbiology and biotechnology 2005;69(1):22-8.
2005: Ito Masaaki; Inouye Kuniyo
Catalytic properties of an organic solvent-resistant tyrosinase from Streptomyces sp. REN-21 and its high-level production in E. coli.
Journal of biochemistry 2005;138(4):355-62.
2005: Okumura Shiro; Saitoh Hiroyuki; Ishikawa Tomoyuki; Wasano Naoya; Yamashita Satoko; Kusumoto Ken-Ichi; Akao Tetsuyuki; Mizuki Eiichi; Ohba Michio; Inouye Kuniyo
Identification of a novel cytotoxic protein, Cry45Aa, from Bacillus thuringiensis A1470 and its selective cytotoxic activity against various mammalian cell lines.
Journal of agricultural and food chemistry 2005;53(16):6313-8.
2005: Yamamoto Keiko; Uchida Eriko; Urushino Naoko; Sakaki Toshiyuki; Kagawa Norio; Sawada Natsumi; Kamakura Masaki; Kato Shigeaki; Inouye Kuniyo; Yamada Sachiko
Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1.
The Journal of biological chemistry 2005;280(34):30511-6.
2005: Kamo Masayuki; Inouye Kuniyo; Nagata Koji; Tanokura Masaru
Preliminary X-ray crystallographic analysis of thermolysin in the presence of 4 M NaCl.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 6):710-2.
2005: Abe Daisuke; Sakaki Toshiyuki; Kusudo Tatsuya; Kittaka Atsushi; Saito Nozomi; Suhara Yoshitomo; Fujishima Toshie; Takayama Hiroaki; Hamamoto Hiromi; Kamakura Masaki; Ohta Miho; Inouye Kuniyo
Metabolism of 2 alpha-propoxy-1 alpha,25-dihydroxyvitamin D3 and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 by human CYP27A1 and CYP24A1.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(6):778-84.
2005: Tsuzuki Satoshi; Murai Nobuhito; Miyake Yuka; Inouye Kuniyo; Hirayasu Hirofumi; Iwanaga Toshihiko; Fushiki Tohru
Evidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytes.
The Biochemical journal 2005;388(Pt 2):679-87.
2005: Kamao Maya; Hatakeyama Susumi; Sakaki Toshiyuki; Sawada Natsumi; Inouye Kuniyo; Kubodera Noboru; Reddy G Satyanarayana; Okano Toshio
Measurement and characterization of C-3 epimerization activity toward vitamin D3.
Archives of biochemistry and biophysics 2005;436(1):196-205.
2005: Muta Yuko; Oneda Hiroshi; Inouye Kuniyo
Anomalous pH-dependence of the activity of human matrilysin (matrix metalloproteinase-7) as revealed by nitration and amination of its tyrosine residues.
The Biochemical journal 2005;386(Pt 2):263-70.
2005: Okumura Shiro; Akao Tetsuyuki; Yamashita Satoko; Ichimatsu Tokio; Inouye Kuniyo
Determination of Biotinylated Proteins as an Index for Purification of Plasma Membrane using Surface Plasmon Resonance-based Optical Biosensor.
Cytotechnology 2005;47(1-3):59-67.
2005: Sakaki Toshiyuki; Kagawa Norio; Yamamoto Keiko; Inouye Kuniyo
Metabolism of vitamin D3 by cytochromes P450.
Frontiers in bioscience : a journal and virtual library 2005;10():119-34.
2005: Kasai Noriyuki; Sakaki Toshiyuki; Shinkyo Raku; Ikushiro Shin-Ichi; Iyanagi Takashi; Ohta Miho; Inouye Kuniyo
Metabolism of 26,26,26,27,27,27-F6-1 alpha,23S,25-trihydroxyvitamin D3 by human UDP-glucuronosyltransferase 1A3.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(1):102-7.
2005: Matsumiya Y; Nishikawa K; Inouye K; Kubo M
Mutational effect for stability in a conserved region of thermolysin.
Letters in applied microbiology 2005;40(5):329-34.
2004: Sulistyaningdyah Woro Triarsi; Ogawa Jun; Li Qing-Shan; Shinkyo Raku; Sakaki Toshiyuki; Inouye Kuniyo; Schmid Rolf D; Shimizu Sakayu
Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant.
Biotechnology letters 2004;26(24):1857-60.
2004: Muta Yuko; Oneda Hiroshi; Inouye Kuniyo
Inhibitory effects of alcohols on the activity of human matrix metalloproteinase 7 (matrilysin).
Bioscience, biotechnology, and biochemistry 2004;68(12):2649-52.
2004: Shinkyo Raku; Sakaki Toshiyuki; Kamakura Masaki; Ohta Miho; Inouye Kuniyo
Metabolism of vitamin D by human microsomal CYP2R1.
Biochemical and biophysical research communications 2004;324(1):451-7.
2004: Oneda Hiroshi; Inouye Kuniyo
Detection of antigen-antibody reaction using a fluorescent probe and its application to homogeneous competitive-type immunoassay for insulin.
Bioscience, biotechnology, and biochemistry 2004;68(10):2190-2.
2004: Uchida Eriko; Kagawa Norio; Sakaki Toshiyuki; Urushino Naoko; Sawada Natsumi; Kamakura Masaki; Ohta Miho; Kato Shigeaki; Inouye Kuniyo
Purification and characterization of mouse CYP27B1 overproduced by an Escherichia coli system coexpressing molecular chaperonins GroEL/ES.
Biochemical and biophysical research communications 2004;323(2):505-11.
2004: Muta Yuko; Oyama Sohei; Umezawa Toshiaki; Shimada Mikio; Inouye Kuniyo
Inhibitory effects of lignans on the activity of human matrix metalloproteinase 7 (matrilysin).
Journal of agricultural and food chemistry 2004;52(19):5888-94.
2004: Kusudo Tatsuya; Sakaki Toshiyuki; Abe Daisuke; Fujishima Toshie; Kittaka Atsushi; Takayama Hiroaki; Hatakeyama Susumi; Ohta Miho; Inouye Kuniyo
Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1.
Biochemical and biophysical research communications 2004;321(4):774-82.
2004: Oneda Hiroshi; Muta Yuko; Inouye Kuniyo
Substrate-dependent activation of thermolysin by salt.
Bioscience, biotechnology, and biochemistry 2004;68(8):1811-3.
2004: Kasai Noriyuki; Sakaki Toshiyuki; Shinkyo Raku; Ikushiro Shin-Ichi; Iyanagi Takashi; Kamao Maya; Okano Toshio; Ohta Miho; Inouye Kuniyo
Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(8):870-5.
2004: Nagai Kouhei; Inouye Kuniyo
Insights into the reaction mechanism of the coagulation of soy protein isolates induced by subtilisin carlsberg.
Journal of agricultural and food chemistry 2004;52(15):4921-7.
2004: Sawada Natsumi; Sakaki Toshiyuki; Yoneda Sachiyo; Kusudo Tatsuya; Shinkyo Raku; Ohta Miho; Inouye Kuniyo
Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1.
Biochemical and biophysical research communications 2004;320(1):156-64.
2004: Yamamoto Keiko; Masuno Hiroyuki; Sawada Natsumi; Sakaki Toshiyuki; Inouye Kuniyo; Ishiguro Masaji; Yamada Sachiko
Homology modeling of human 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):167-71.
2004: Matsumiya Yoshiki; Nishikawa Kouji; Aoshima Hisae; Inouye Kuniyo; Kubo Motoki
Analysis of autodegradation sites of thermolysin and enhancement of its thermostability by modifying Leu155 at an autodegradation site.
Journal of biochemistry 2004;135(4):547-53.
2004: Sawada Natsumi; Kusudo Tatsuya; Sakaki Toshiyuki; Hatakeyama Susumi; Hanada Makoto; Abe Daisuke; Kamao Maya; Okano Toshio; Ohta Miho; Inouye Kuniyo
Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.
Biochemistry 2004;43(15):4530-7.
2004: Kamao Maya; Tatematsu Syuichiro; Hatakeyama Susumi; Sakaki Toshiyuki; Sawada Natsumi; Inouye Kuniyo; Ozono Keiichi; Kubodera Noboru; Reddy G Satyanarayana; Okano Toshio
C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.
The Journal of biological chemistry 2004;279(16):15897-907.
2004: Oneda Hiroshi; Lee Seungjae; Inouye Kuniyo
Inhibitory effect of 0.19 alpha-amylase inhibitor from wheat kernel on the activity of porcine pancreas alpha-amylase and its thermal stability.
Journal of biochemistry 2004;135(3):421-7.
2004: Lee Soo-Bok; Nam Ki-chang; Lee Sung-Joon; Lee Jong-Ho; Inouye Kuniyo; Park Kwan-Hwa
Antioxidative effects of glycosyl-ascorbic acids synthesized by maltogenic amylase to reduce lipid oxidation and volatiles production in cooked chicken meat.
Bioscience, biotechnology, and biochemistry 2004;68(1):36-43.
2003: Oneda Hiroshi; Inouye Kuniyo
Effect of nitration on the activity of bovine erythrocyte Cu,Zn-superoxide dismutase (BESOD) and a kinetic analysis of its dimerization-dissociation reaction as examined by subunit exchange between the native and nitrated BESODs.
Journal of biochemistry 2003;134(5):683-90.
2003: Kusudo Tatsuya; Sakaki Toshiyuki; Abe Daisuke; Fujishima Toshie; Kittaka Atsushi; Takayama Hiroaki; Ohta Miho; Inouye Kuniyo
Metabolism of 20-epimer of 1alpha,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.
Biochemical and biophysical research communications 2003;309(4):885-92.
2003: Ikezawa Nobuhiro; Tanaka Masaru; Nagayoshi Masanori; Shinkyo Raku; Sakaki Toshiyuki; Inouye Kuniyo; Sato Fumihiko
Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.
The Journal of biological chemistry 2003;278(40):38557-65.
2003: Nakamura Koji; Suzuki Takao; Hasegawa Masazumi; Kato Yoshio; Sasaki Hiroo; Inouye Kuniyo
Characterization of p-aminobenzamidine-based sorbent and its use for high-performance affinity chromatography of trypsin-like proteases.
Journal of chromatography. A 2003;1009(1-2):133-9.
2003: Shinkyo Raku; Sakaki Toshiyuki; Takita Teisuke; Ohta Miho; Inouye Kuniyo
Generation of 2,3,7,8-TCDD-metabolizing enzyme by modifying rat CYP1A1 through site-directed mutagenesis.
Biochemical and biophysical research communications 2003;308(3):511-7.
2003: Kusudo Tatsuya; Sakaki Toshiyuki; Inouye Kuniyo
Purification and characterization of purple acid phosphatase PAP1 from dry powder of sweet potato.
Bioscience, biotechnology, and biochemistry 2003;67(7):1609-11.
2003: Sakaki Toshiyuki; Sawada Natsumi; Abe Daisuke; Komai Koichiro; Shiozawa Shunichi; Nonaka Yasuki; Nakagawa Kimie; Okano Toshio; Ohta Miho; Inouye Kuniyo
Metabolism of 26,26,26,27,27,27-F6-1alpha,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.
Biochemical pharmacology 2003;65(12):1957-65.
2003: Oneda Hiroshi; Shiihara Misa; Inouye Kuniyo
Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (matrilysin).
Journal of biochemistry 2003;133(5):571-6.
2003: Tanaka Akiyoshi; Sugimoto Hayuki; Muta Yuko; Mizuno Takafumi; Senoo Keishi; Obata Hitoshi; Inouye Kuniyo
Differential scanning calorimetry of the effects of Ca2+ on the thermal unfolding of Pseudomonas cepacia lipase.
Bioscience, biotechnology, and biochemistry 2003;67(1):207-10.
2003: Takita Teisuke; Nakagoshi Makoto; Inouye Kuniyo; Tonomura Ben'ichiro
Lysyl-tRNA synthetase from Bacillus stearothermophilus: the Trp314 residue is shielded in a non-polar environment and is responsible for the fluorescence changes observed in the amino acid activation reaction.
Journal of molecular biology 2003;325(4):677-95.
2003: Shinkyo Raku; Sakaki Toshiyuki; Ohta Miho; Inouye Kuniyo
Metabolic pathways of dioxin by CYP1A1: species difference between rat and human CYP1A subfamily in the metabolism of dioxins.
Archives of biochemistry and biophysics 2003;409(1):180-7.
2002: Muta Yuko; Inouye Kuniyo
Inhibitory effects of alcohols on thermolysin activity as examined using a fluorescent substrate.
Journal of biochemistry 2002;132(6):945-51.
2002: Nakamura Koji; Suzuki Takao; Kamichika Toshito; Hasegawa Masazumi; Kato Yoshio; Sasaki Hiroo; Inouye Kuniyo
Evaluation and applications of a new dye affinity adsorbent.
Journal of chromatography. A 2002;972(1):21-5.
2002: Inouye Kuniyo; Shinkyo Raku; Takita Teisuke; Ohta Miho; Sakaki Toshiyuki
Metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) by human cytochrome P450-dependent monooxygenase systems.
Journal of agricultural and food chemistry 2002;50(19):5496-502.
2002: Takita Teisuke; Inouye Kuniyo
Transition state stabilization by the N-terminal anticodon-binding domain of lysyl-tRNA synthetase.
The Journal of biological chemistry 2002;277(32):29275-82.
2002: Sakaki Toshiyuki; Shinkyo Raku; Takita Teisuke; Ohta Miho; Inouye Kuniyo
Biodegradation of polychlorinated dibenzo-p-dioxins by recombinant yeast expressing rat CYP1A subfamily.
Archives of biochemistry and biophysics 2002;401(1):91-8.
2002: Inouye Kuniyo; Shiihara Misa; Uno Tadashi; Takita Teisuke
Deodorization of soybean proteins by enzymatic and physicochemical treatments.
Journal of agricultural and food chemistry 2002;50(6):1652-8.
2002: Inouye Kuniyo; Nagai Kouhei; Takita Teisuke
Coagulation of soy protein isolates induced by subtilisin Carlsberg.
Journal of agricultural and food chemistry 2002;50(5):1237-42.
2002: Inouye Kuniyo; Ueno Iori; Yokoyama Shin-ichi; Sakaki Toshiyuki
Development of a synchronous enzyme-reaction system for a highly sensitive enzyme immunoassay.
Journal of biochemistry 2002;131(1):97-105.
2001: Sawada N; Sakaki T; Kitanaka S; Kato S; Inouye K
Structure-function analysis of CYP27B1 and CYP27A1. Studies on mutants from patients with vitamin D-dependent rickets type I (VDDR-I) and cerebrotendinous xanthomatosis (CTX).
European journal of biochemistry / FEBS 2001;268(24):6607-15.
2001: Kuzuya K; Inouye K
Effects of cobalt-substitution of the active zinc ion in thermolysin on its activity and active-site microenvironment.
Journal of biochemistry 2001;130(6):783-8.
2001: Mizutani S; Inouye K; Koide H; Kaziro Y
Involvement of B-Raf in Ras-induced Raf-1 activation.
FEBS letters 2001;507(3):295-8.
2001: Inouye K; Ohnaka S
Pepsin digestion of a mouse monoclonal antibody of IgG1 class formed F(ab')(2) fragments in which the light chains as well as the heavy chains were truncated.
Journal of biochemical and biophysical methods 2001;48(1):23-32.
2001: Oneda H; Inouye K
Interactions of human matrix metalloproteinase 7 (matrilysin) with the inhibitors thiorphan and R-94138.
Journal of biochemistry 2001;129(3):429-35.
2001: Okumura S; Akao T; Mizuki E; Ohba M; Inouye K
Screening of the Bacillus thuringiensis Cry1Ac delta-endotoxin on the artificial phospholipid monolayer incorporated with brush border membrane vesicles of Plutella xylostella by optical biosensor technology.
Journal of biochemical and biophysical methods 2001;47(3):177-88.
2001: Inouye K; Kondo S; Yamamura M; Nakanishi D; Sakaki T
Inhibitory effects of detergents on rat CYP1A1-dependent monooxygenase: comparison of mixed and fused systems consisting of rat CYP 1A1 and yeast NADPH-P450 reductase.
Biochemical and biophysical research communications 2001;280(5):1346-51.
2001: Inouye K; Sakaki T
Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24).
Biotechnology annual review 2001;7():179-94.
2000: Oneda H; Inouye K
Effects of dimethyl sulfoxide, temperature, and sodium chloride on the activity of human matrix metalloproteinase 7 (matrilysin).
Journal of biochemistry 2000;128(5):785-91.
2000: Sakaki T; Sawada N; Komai K; Shiozawa S; Yamada S; Yamamoto K; Ohyama Y; Inouye K
Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24.
European journal of biochemistry / FEBS 2000;267(20):6158-65.
2000: Inouye K; Mizokawa T; Saito A; Tonomura B; Ohkawa H
Biphasic kinetic behavior of rat cytochrome P-4501A1-dependent monooxygenation in recombinant yeast microsomes.
Biochimica et biophysica acta 2000;1481(2):265-72.
2000: Inouye K; Tanaka H; Oneda H
States of tryptophyl residues and stability of recombinant human matrix metalloproteinase 7 (matrilysin) as examined by fluorescence.
Journal of biochemistry 2000;128(3):363-9.
2000: Sawada N; Sakaki T; Ohta M; Inouye K
Metabolism of vitamin D(3) by human CYP27A1.
Biochemical and biophysical research communications 2000;273(3):977-84.
2000: Inouye K; Saito A; Orita M; Tonomura B; Imaishi H; Ohkawa H
Inhibitory effects of 1,4-naphthoquinone derivatives on rat cytochrome P4501A1-dependent monooxygenase activity in recombinant yeast microsomes.
Journal of biochemistry 2000;127(6):1041-6.
2000: Takita T; Shimizu N; Sukata T; Hashimoto S; Akita E; Yokota T; Esaki N; Soda K; Inouye K; Tonomura B
Lysyl-tRNA synthetase of Bacillus stearothermophilus molecular cloning and expression of the gene.
Bioscience, biotechnology, and biochemistry 2000;64(2):432-7.
2000: Inouye K; Mizutani S; Koide H; Kaziro Y
Formation of the Ras dimer is essential for Raf-1 activation.
The Journal of biological chemistry 2000;275(6):3737-40.
1999: Oneda H; Inouye K
Refolding and recovery of recombinant human matrix metalloproteinase 7 (matrilysin) from inclusion bodies expressed by Escherichia coli.
Journal of biochemistry 1999;126(5):905-11.
1999: Sawada N; Sakaki T; Kitanaka S; Takeyama K; Kato S; Inouye K
Enzymatic properties of human 25-hydroxyvitamin D3 1alpha-hydroxylase coexpression with adrenodoxin and NADPH-adrenodoxin reductase in Escherichia coli.
European journal of biochemistry / FEBS 1999;265(3):950-6.
1999: Inouye K; Mae T; Kondo S; Ohkawa H
Inhibitory effects of vitamin A and vitamin K on rat cytochrome P4501A1-dependent monooxygenase activity.
Biochemical and biophysical research communications 1999;262(2):565-9.
1999: Tanaka A; Okuda K; Senoo K; Obata H; Inouye K
Guanidine hydrochloride-induced denaturation of Pseudomonas cepacia lipase.
Journal of biochemistry 1999;126(2):382-6.
1999: Sakaki T; Sawada N; Nonaka Y; Ohyama Y; Inouye K
Metabolic studies using recombinant escherichia coli cells producing rat mitochondrial CYP24 CYP24 can convert 1alpha,25-dihydroxyvitamin D3 to calcitroic acid.
European journal of biochemistry / FEBS 1999;262(1):43-8.
1999: Kondo S; Sakaki T; Ohkawa H; Inouye K
Electrostatic interaction between cytochrome P450 and NADPH-P450 reductase: comparison of mixed and fused systems consisting of rat cytochrome P450 1A1 and yeast NADPH-P450 reductase.
Biochemical and biophysical research communications 1999;257(2):273-8.
1999: Sakaki T; Sawada N; Takeyama K; Kato S; Inouye K
Enzymatic properties of mouse 25-hydroxyvitamin D3 1 alpha-hydroxylase expressed in Escherichia coli.
European journal of biochemistry / FEBS 1999;259(3):731-8.
1998: Inouye K; Kurokawa M; Nishikawa S; Tsukada M
Use of Bombyx mori silk fibroin as a substratum for cultivation of animal cells.
Journal of biochemical and biophysical methods 1998;37(3):159-64.
1998: Inouye K; Kuzuya K; Tonomura B
Sodium chloride enhances markedly the thermal stability of thermolysin as well as its catalytic activity.
Biochimica et biophysica acta 1998;1388(1):209-14.
1998: Inouye K; Lee S B; Tonomura B
Effects of nitration and amination of tyrosyl residues in thermolysin on its hydrolytic activity and its remarkable activation by salts.
Journal of biochemistry 1998;124(1):72-8.
1998: Takita T; Akita E; Inouye K; Tonomura B
Lysyl-tRNA synthetase from Bacillus stearothermophilus. Stopped-flow kinetic analysis of enzyme.lysyladenylate formation.
Journal of biochemistry 1998;124(1):45-50.
1998: Inouye K; Kuzuya K; Tonomura B
Effect of salts on the solubility of thermolysin: a remarkable increase in the solubility as well as the activity by the addition of salts without aggregation or dispersion of thermolysin.
Journal of biochemistry 1998;123(5):847-52.
1998: Inouye K; Mazda N; Kubo M
Need for aromatic residue at position 115 for proteolytic activity found by site-directed mutagenesis of tryptophan 115 in thermolysin.
Bioscience, biotechnology, and biochemistry 1998;62(4):798-800.
1997: Inouye K; Lee S B; Nambu K; Tonomura B
Effects of pH, temperature, and alcohols on the remarkable activation of thermolysin by salts.
Journal of biochemistry 1997;122(2):358-64.
1997: Takita T; Hashimoto S; Ohkubo Y; Muto T; Shimizu N; Sukata T; Inouye K; Hiromi K; Tonomura B
Lysyl-tRNA synthetase from Bacillus stearothermophilus. Formation and isolation of an enzyme-lysyladenylate complex and its analogue.
Journal of biochemistry 1997;121(2):244-50.
1997: Lee S B; Inouye K; Tonomura B
The states of tyrosyl residues in thermolysin as examined by nitration and pH-dependent ionization.
Journal of biochemistry 1997;121(2):231-7.
1996: Takita T; Ohkubo Y; Shima H; Muto T; Shimizu N; Sukata T; Ito H; Saito Y; Inouye K; Hiromi K; Tonomura B
Lysyl-tRNA synthetase from Bacillus stearothermophilus. Purification, and fluorometric and kinetic analysis of the binding of substrates, L-lysine and ATP.
Journal of biochemistry 1996;119(4):680-9.
1996: Inouye K; Lee S B; Tonomura B
Effect of amino acid residues at the cleavable site of substrates on the remarkable activation of thermolysin by salts.
The Biochemical journal 1996;315 ( Pt 1)():133-8.
1995: Inouye K; Izawa S; Saito A; Tonomura B
Effects of alcohols on the hydrolysis of colominic acid catalyzed by Streptococcus neuraminidase.
Journal of biochemistry 1995;117(3):629-34.
1994: Inouye K; Kuzuya K; Tonomura B
A spectrophotometric study on the interaction of thermolysin with chloride and bromide ions, and the state of tryptophyl residue 115.
Journal of biochemistry 1994;116(3):530-5.
1994: Inouye K
[Halophilic enzymes]
Seikagaku. The Journal of Japanese Biochemical Society 1994;66(5):446-50.
1994: Inouye K; Osaki A; Tonomura B
Dissociation of dimer of bovine erythrocyte Cu,Zn-superoxide dismutase and activity of the monomer subunit: effects of urea, temperature, and enzyme concentration.
Journal of biochemistry 1994;115(3):507-15.
1993: Masuda-Momma K; Shimakawa T; Inouye K; Hiromi K; Kojima S; Kumagai I; Miura K; Tonomura B
Identification of amino acid residues responsible for the changes of absorption and fluorescence spectra on the binding of subtilisin BPN' and Streptomyces subtilisin inhibitor.
Journal of biochemistry 1993;114(6):906-11.
1993: Masuda-Momma K; Hatanaka T; Inouye K; Kanaori K; Tamura A; Akasaka K; Kojima S; Kumagai I; Miura K; Tonomura B
Interaction of subtilisin BPN' and recombinant Streptomyces subtilisin inhibitors with substituted P1 site residues.
Journal of biochemistry 1993;114(4):553-9.

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