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Claudine Isaacs

Research Profile

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Genetic Counseling

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Vanessa B Sheppard; Karen Smith; Felicia Snead; Shawna C Willey; Marc Boisvert; Felicity W K Harper; Fikru Hirpa; Sara Horton; Claudine Isaacs; Yvonne Jennings; Minetta C Liu; Gheorghe Luta; Jeanne S Mandelblatt
Narrowing racial gaps in breast cancer chemotherapy initiation: the role of the patient-provider relationship.
Jeanne S Mandelblatt; Vanessa B Sheppard; Michelle Tallarico; Kathryn Taylor; Leigh Anne Faul; Claudine Isaacs; Gheorghe Luta; Solomon B Makgoeng; William T Barry; Harvey J Cohen
Patient and physician decision styles and breast cancer chemotherapy use in older women: Cancer and Leukemia Group B protocol 369901.
Nadiyah Sulayman; Kristi D Graves; Claudine Isaacs; Beth N Peshkin; Marc D Schwartz; Elizabeth Spellman; Suzanne C O'Neill
Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay: The Impact of Decision Style in Women with Intermediate RS.

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2013: Vanessa B Sheppard; Karen Smith; Felicia Snead; Shawna C Willey; Marc Boisvert; Felicity W K Harper; Fikru Hirpa; Sara Horton; Claudine Isaacs; Yvonne Jennings; Minetta C Liu; Gheorghe Luta; Jeanne S Mandelblatt
Narrowing racial gaps in breast cancer chemotherapy initiation: the role of the patient-provider relationship.
Breast cancer research and treatment 2013;139(1):207-16.
2012: Jeanne S Mandelblatt; Vanessa B Sheppard; Michelle Tallarico; Kathryn Taylor; Leigh Anne Faul; Claudine Isaacs; Gheorghe Luta; Solomon B Makgoeng; William T Barry; Harvey J Cohen
Patient and physician decision styles and breast cancer chemotherapy use in older women: Cancer and Leukemia Group B protocol 369901.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(21):2609-14.
2012: Nadiyah Sulayman; Kristi D Graves; Claudine Isaacs; Beth N Peshkin; Marc D Schwartz; Elizabeth Spellman; Suzanne C O'Neill
Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay: The Impact of Decision Style in Women with Intermediate RS.
Journal of cancer epidemiology 2012;2012():728290.
2011: Kristi D Graves; Toni Michelle Harrison; Claudine Isaacs; Beth N Peshkin; Juleen Christopher; Vanessa B Sheppard
Providers' perceptions and practices regarding BRCA1/2 genetic counseling and testing in African American women.
Journal of genetic counseling 2011;20(6):674-89.
2011: Claudine Isaacs; Pia Herbolsheimer; Minetta C Liu; Mary Wilkinson; YVONNE OTTAVIANO; Gina G Chung; Robert Warren; Jennifer Eng-Wong; Philip Cohen; Karen L Smith; Karen Creswell; Antonella Novielli; Rebecca Slack
Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer.
Breast cancer research and treatment 2011;125(1):137-43.
2010: Suzanne O'Neill; Heiddis B Valdimarsdottir; Tiffani A Demarco; Beth N Peshkin; Kristi D Graves; Karen Brown; Karen E Hurley; Claudine Isaacs; Sharon Hecker; Marc D Schwartz
BRCA1/2 test results impact risk management attitudes, intentions, and uptake.
Breast cancer research and treatment 2010;124(3):755-64.
2010: Susan M Domchek; Tara Friebel; Judy E Garber; Claudine Isaacs; Ellen Matloff; Rosalind Eeles; D Gareth Evans; Wendy Rubinstein; Christian F Singer; Stephen Rubin; Henry T Lynch; Mary B Daly; Jeffrey N Weitzel; Patricia Anne Ganz; Gabriella Pichert; Olufunmilayo I Olopade; Gail Tomlinson; Nadine Tung; Joanne L Blum; Fergus J. Couch; Timothy R Rebbeck
Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers.
Breast cancer research and treatment 2010;124(1):195-203.
2010: Susan M Domchek; Tara Friebel; Christian F Singer; D Gareth Evans; Henry T Lynch; Claudine Isaacs; Judy E Garber; Susan L Neuhausen; Ellen Matloff; Rosalind Eeles; Gabriella Pichert; Laura Van t'veer; Nadine Tung; Jeffrey N Weitzel; Fergus J. Couch; Wendy S Rubinstein; Patricia Anne Ganz; Mary B Daly; Olufunmilayo I Olopade; Gail Tomlinson; Joellen Schildkraut; Joanne L Blum; Timothy R Rebbeck
Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality.
JAMA : the journal of the American Medical Association 2010;304(9):967-75.
2010: Jeanne S Mandelblatt; Vanessa B Sheppard; Arti Hurria; Gretchen Kimmick; Claudine Isaacs; Kathryn L Taylor; Alice B Kornblith; Anne-Michelle Noone; Gheorghe Luta; Michelle Tallarico; William T Barry; Lisa Hunegs; Robin Zon; Michael Naughton; Eric Winer; Clifford Hudis; Stephen B Edge; Harvey Jay Cohen; Hyman Muss
Breast cancer adjuvant chemotherapy decisions in older women: the role of patient preference and interactions with physicians.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(19):3146-53.
2010: Beth N Peshkin; Michelle L Alabek; Claudine Isaacs
BRCA1/2 mutations and triple negative breast cancers.
Breast disease 2010;32(1-2):25-33.
2010: Jennifer Eng-Wong; Claudine Isaacs
Prediction of benefit from adjuvant treatment in patients with breast cancer.
Clinical breast cancer 2010;10 Suppl 1():E32-7.
2009: Minetta C Liu; Peter G Shields; Robert D Warren; Philip Cohen; Mary Wilkinson; YVONNE OTTAVIANO; Suman B Rao; Jennifer Eng-Wong; Francoise Seillier-Moiseiwitsch; Anne-Michelle Noone; Claudine Isaacs
Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(31):5153-9.
2009: Danielle Vicus; Barry Rosen; Jan Lubinski; Susan Domchek; Noah D Kauff; Henry T Lynch; Claudine Isaacs; Nadine Tung; Ping Sun; Steven A Narod
Tamoxifen and the risk of ovarian cancer in BRCA1 mutation carriers.
Gynecologic oncology 2009;115(1):135-7.
2009: Trishna Goswami; Minal Shah; Claudine Isaacs
Novel molecular prognostic markers in breast cancer.
Expert opinion on medical diagnostics 2009;3(5):523-32.
2009: Timothy R Rebbeck; Nandita Mitra; Susan M Domchek; Fei Wan; Shaokun Chuai; Tara Friebel; Saarene Panossian; Amanda Spurdle; Georgia Chenevix-Trench; Christian F Singer; Georg Pfeiler; Susan L Neuhausen; Henry T Lynch; Judy E Garber; Jeffrey N Weitzel; Claudine Isaacs; Fergus J. Couch; Steven A Narod; Wendy S Rubinstein; Gail Tomlinson; Patricia Anne Ganz; Olufunmilayo I Olopade; Nadine Tung; Joanne L Blum; Roger A. Greenberg; Katherine L Nathanson; Mary B Daly
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
Cancer research 2009;69(14):5801-10.
2009: Marc D Schwartz; Heiddis B Valdimarsdottir; Tiffani A Demarco; Beth N Peshkin; William Lawrence; Jessica Rispoli Joines; Karen Brown; Claudine Isaacs; Suzanne O'Neill; Rebecca A Shelby; Sherry C Grumet; Margaret M McGovern; Sarah Garnett; Heather Bremer; Suzanne Leaman; Kathryn O'Mara; Sarah Kelleher; Kathryn Komaridis
Randomized trial of a decision aid for BRCA1/BRCA2 mutation carriers: impact on measures of decision making and satisfaction.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2009;28(1):11-9.
2008: Kristi D Graves; Elmer E Huerta; Jennifer Cullen; Elizabeth Kaufman; Vanessa B Sheppard; George Luta; Claudine Isaacs; Marc D Schwartz; Jeanne S Mandelblatt
Perceived risk of breast cancer among Latinas attending community clinics: risk comprehension and relationship with mammography adherence.
Cancer causes & control : CCC 2008;19(10):1373-82.
2008: Andrea Eisen; Jan Lubinski; Jacek Gronwald; Pal Moller; Henry T Lynch; Jan Klijn; Charmaine Kim-Sing; Susan L Neuhausen; Lucy Gilbert; Parviz Ghadirian; Siranoush Manoukian; Gad Rennert; Eitan Friedman; Claudine Isaacs; Eliot Rosen; Barry Rosen; Mary Daly; Ping Sun; Steven A Narod
Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers.
Journal of the National Cancer Institute 2008;100(19):1361-7.
2008: Kelly A Metcalfe; Jan Lubinski; Parviz Ghadirian; Henry Lynch; Charmaine Kim-Sing; Eitan Friedman; William D Foulkes; Susan M Domchek; Peter Ainsworth; Claudine Isaacs; Nadine Tung; Jacek Gronwald; Shelly Cummings; Teresa Wagner; Siranoush Manoukian; Pål Møller; Jeffrey N Weitzel; Ping Sun; Steven A Narod
Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(7):1093-7.
2007: Tara Friebel; Susan M Domchek; Susan L Neuhausen; Theresa Wagner; D Gareth Evans; Claudine Isaacs; Judy E Garber; Mary B Daly; Rosalind Eeles; Ellen Matloff; Gail Tomlinson; Henry T Lynch; Nadine Tung; Joanne L Blum; Jeffrey N Weitzel; Wendy S Rubinstein; Patricia Anne Ganz; Fergus J. Couch; Timothy R Rebbeck
Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers.
Clinical breast cancer 2007;7(11):875-82.
2007: Kristi D Graves; Lisa M Moss; Camille L Jasper; Tiffani A Demarco; Beth N Peshkin; Claudine Isaacs; Marc D Schwartz
Predictors of enrollment into a familial cancer registry by individuals at high risk for BRCA1/2.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(12):2763-7.
2007: Tiffani A Demarco; Karen L Smith; Rachel H Nusbaum; Beth N Peshkin; Marc D Schwartz; Claudine Isaacs
Practical aspects of delivering hereditary cancer risk counseling.
Seminars in oncology 2007;34(5):369-78.
2007: Kristi D Graves; Beth N Peshkin; Chanita Hughes Halbert; Tiffani A Demarco; Claudine Isaacs; Marc D Schwartz
Predictors and outcomes of contralateral prophylactic mastectomy among breast cancer survivors.
Breast cancer research and treatment 2007;104(3):321-9.
2007: Kenneth P Tercyak; Beth N Peshkin; Barbara M Brogan; Tiffani A Demarco; Marie Pennanen; Shawna C Willey; Colette Magnant; Sarah Rogers; Claudine Isaacs; Marc D Schwartz
Quality of life after contralateral prophylactic mastectomy in newly diagnosed high-risk breast cancer patients who underwent BRCA1/2 gene testing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(3):285-91.
2007: Rachel H Nusbaum; Claudine Isaacs
Management updates for women with a BRCA1 or BRCA2 mutation.
Molecular diagnosis & therapy 2007;11(3):133-44.
2006: Deepa S Subramaniam; Claudine Isaacs
Does prophylactic surgery reduce the risk of gynecologic cancers arising from the Lynch syndrome?
Nature clinical practice. Oncology 2006;3(8):426-7.
2005: Beth N Peshkin; Claudine Isaacs
Evaluation and management of women with BRCA1/2 mutations.
Oncology (Williston Park, N.Y.) 2005;19(11):1451-9; discussion 1459-68 1474.
2005: Vered Stearns; Rebecca Slack; Nancy Greep; Ronda Henry-Tilman; Michael Osborne; Craig A Bunnell; Lynda Ullmer; Ann Gallagher; Jennifer Cullen; Edmund Gehan; Daniel F Hayes; Claudine Isaacs
Paroxetine is an effective treatment for hot flashes: results from a prospective randomized clinical trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):6919-30.
2005: Eliot M Rosen; Saijun Fan; Claudine Isaacs
BRCA1 in hormonal carcinogenesis: basic and clinical research.
Endocrine-related cancer 2005;12(3):533-48.
2005: Marc D Schwartz; Caryn Lerman; Barbara M Brogan; Beth N Peshkin; Claudine Isaacs; Tiffani A Demarco; Chanita Hughes Halbert; Marie Pennanen; Clinton Finch
Utilization of BRCA1/BRCA2 mutation testing in newly diagnosed breast cancer patients.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(4):1003-7.
2005: Deepa S Subramaniam; Claudine Isaacs
Utilizing prognostic and predictive factors in breast cancer.
Current treatment options in oncology 2005;6(2):147-59.
2004: Vered Stearns; Ann Gallagher; Celina G Kleer; Baljit Singh; Matthew Freedman; Bassem R Haddad; Claudine Isaacs; Robert Warren; Martha Brown; Jennifer Cullen; Bruce J Trock; Daniel F Hayes
A pilot study to establish a clinical model to perform phase II studies of breast cancer chemopreventive agents in women at high risk with biomarkers as surrogate endpoints for activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8332-40.
2004: Marc D Schwartz; Caryn Lerman; Barbara M Brogan; Beth N Peshkin; Chanita Hughes Halbert; Tiffani A Demarco; William Lawrence; David Main; Clinton Finch; Colette Magnant; Marie Pennanen; Theodore Tsangaris; Shawna C Willey; Claudine Isaacs
Impact of BRCA1/BRCA2 counseling and testing on newly diagnosed breast cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(10):1823-9.
2004: Claudine Isaacs; Luciane Cavalli; Yoram Cohen; Marie Pennanen; Lalita K Shankar; Matthew Freedman; Baljit Singh; Minetta Liu; Ann Gallagher; Janice D Rone; Robert B Dickson; David Sidransky; Bassem R Haddad
Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients.
Breast cancer research and treatment 2004;84(2):99-105.
2004: Luciane Cavalli; Baljit Singh; Claudine Isaacs; Robert B Dickson; Bassem R Haddad
Loss of heterozygosity in normal breast epithelial tissue and benign breast lesions in BRCA1/2 carriers with breast cancer.
Cancer genetics and cytogenetics 2004;149(1):38-43.
2003: Beth N Peshkin; Claudine Isaacs; Clinton Finch; Sheryl Kent; Marc D Schwartz
Tamoxifen as chemoprevention in BRCA1 and BRCA2 mutation carriers with breast cancer: a pilot survey of physicians.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(23):4322-8.
2003: Marc D Schwartz; Elizabeth Kaufman; Beth N Peshkin; Claudine Isaacs; Chanita Hughes; Tiffani A Demarco; Clinton Finch; Caryn Lerman
Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testing.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(21):4034-41.
2003: Vered Stearns; Baljit Singh; Theodore Tsangaris; Jeanette G Crawford; Antonella Novielli; Matthew J Ellis; Claudine Isaacs; Marie Pennanen; Cecilia Tibery; Ahmad Farhad; Rebecca Slack; Daniel F Hayes
A prospective randomized pilot study to evaluate predictors of response in serial core biopsies to single agent neoadjuvant doxorubicin or paclitaxel for patients with locally advanced breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):124-33.
2002: Vered Stearns; Lynda Ullmer; Juan F Lopez; Yolanda R Smith; Claudine Isaacs; Daniel F Hayes
Hot flushes.
Lancet 2002;360(9348):1851-61.
2002: Beth N Peshkin; Marc D Schwartz; Claudine Isaacs; Chanita Hughes; David Main; Caryn Lerman
Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testing.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(10 Pt 1):1115-8.
2002: Marc D Schwartz; Beth N Peshkin; Chanita Hughes; David Main; Claudine Isaacs; Caryn Lerman
Impact of BRCA1/BRCA2 mutation testing on psychologic distress in a clinic-based sample.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(2):514-20.
2002: Claudine Isaacs; Beth N Peshkin; Marc Schwartz; Tiffani A Demarco; David Main; Caryn Lerman
Breast and ovarian cancer screening practices in healthy women with a strong family history of breast or ovarian cancer.
Breast cancer research and treatment 2002;71(2):103-12.
2001: Marc D Schwartz; JL Benkendorf; Caryn Lerman; Claudine Isaacs; A Ryan-Robertson; L Johnson
Impact of educational print materials on knowledge, attitudes, and interest in BRCA1/BRCA2: testing among Ashkenazi Jewish women.
Cancer 2001;92(4):932-40.
2001: Kenneth P Tercyak; Caryn Lerman; Beth N Peshkin; Chanita Hughes; David Main; Claudine Isaacs; Marc D Schwartz
Effects of coping style and BRCA1 and BRCA2 test results on anxiety among women participating in genetic counseling and testing for breast and ovarian cancer risk.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2001;20(3):217-22.
2001: William F Lawrence; Beth N Peshkin; Wenchi Liang; Claudine Isaacs; Caryn Lerman; Jeanne S Mandelblatt
Cost of genetic counseling and testing for BRCA1 and BRCA2 breast cancer susceptibility mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(5):475-81.
2001: Beth N Peshkin; Tiffani A Demarco; Barbara M Brogan; Caryn Lerman; Claudine Isaacs
BRCA1/2 testing: complex themes in result interpretation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(9):2555-65.
2001: Claudine Isaacs; Vered Stearns; Daniel F Hayes
New prognostic factors for breast cancer recurrence.
Seminars in oncology 2001;28(1):53-67.
2000: Said Baidas; Eric P Winer; G F Fleming; L Harris; J M Pluda; J G Crawford; H Yamauchi; Claudine Isaacs; John Hanfelt; Mariella Tefft; David A Flockhart; M D Johnson; Michael J Hawkins; Marc Lippman; Daniel F Hayes
Phase II evaluation of thalidomide in patients with metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(14):2710-7.
2000: Marc D Schwartz; Chanita Hughes; J Roth; David Main; Beth N Peshkin; Claudine Isaacs; C Kavanagh; Caryn Lerman
Spiritual faith and genetic testing decisions among high-risk breast cancer probands.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(4):381-5.
2000: Vered Stearns; Claudine Isaacs; J Rowland; J Crawford; M J Ellis; R Kramer; William Lawrence; John Hanfelt; Daniel F Hayes
A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(1):17-22.
1997: Claudine Isaacs; N J Robert; F A Bailey; M W Schuster; Beth Overmoyer; M Graham; B Cai; K J Beach; J W Loewy; J A Kaye
Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(11):3368-77.
1997: Chanita Hughes; Andres Gomez-Caminero; JL Benkendorf; Jon F Kerner; Claudine Isaacs; James F Barter; Caryn Lerman
Ethnic differences in knowledge and attitudes about BRCA1 testing in women at increased risk.
Patient education and counseling 1997;32(1-2):51-62.
1994: Claudine Isaacs; S M Swain
Hormone replacement therapy in women with a history of breast carcinoma.
Hematology/oncology clinics of North America 1994;8(1):179-95.