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K Isahara

Research Profile

Chemicals & Drugs

Procedures

Anatomy

Living Beings

Rats
Mouse

Physiology

Enzyme Activation

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Publications

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Masato Koike; Hiroshi Nakanishi; Paul Saftig; Junji Ezaki; K Isahara; Yoshiyuki Ohsawa; W Schulz-Schaeffer; Tsuyoshi Watanabe; Satoshi Waguri; Satoshi Kametaka; Masahiro Shibata; K Yamamoto; Eiki Kominami; Christoph Peters; Kurt von Figura; Yasuo Uchiyama
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons.
Eriko Fujita; Koko Urase; J Egashira; Y Miho; K Isahara; Yasuo Uchiyama; Atsushi Isoai; Hiromichi Kumagai; Keisuke Kuida; N Motoyama; Takashi Momoi
Detection of caspase-9 activation in the cell death of the Bcl-x-deficient mouse embryo nervous system by cleavage sites-directed antisera.
Takahiro Gotow; Masahiro Shibata; S Kanamori; O Tokuno; Yoshiyuki Ohsawa; Naoyuki Sato; K Isahara; Y Yayoi; Tsuyoshi Watanabe; Jean-Francois Leterrier; M Linden; Eiki Kominami; Yasuo Uchiyama
Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells.

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All Publications

2000: Masato Koike; Hiroshi Nakanishi; Paul Saftig; Junji Ezaki; K Isahara; Yoshiyuki Ohsawa; W Schulz-Schaeffer; Tsuyoshi Watanabe; Satoshi Waguri; Satoshi Kametaka; Masahiro Shibata; K Yamamoto; Eiki Kominami; Christoph Peters; Kurt von Figura; Yasuo Uchiyama
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6898-906.
2000: Eriko Fujita; Koko Urase; J Egashira; Y Miho; K Isahara; Yasuo Uchiyama; Atsushi Isoai; Hiromichi Kumagai; Keisuke Kuida; N Motoyama; Takashi Momoi
Detection of caspase-9 activation in the cell death of the Bcl-x-deficient mouse embryo nervous system by cleavage sites-directed antisera.
Brain research. Developmental brain research 2000;122(2):135-47.
2000: Takahiro Gotow; Masahiro Shibata; S Kanamori; O Tokuno; Yoshiyuki Ohsawa; Naoyuki Sato; K Isahara; Y Yayoi; Tsuyoshi Watanabe; Jean-Francois Leterrier; M Linden; Eiki Kominami; Yasuo Uchiyama
Selective localization of Bcl-2 to the inner mitochondrial and smooth endoplasmic reticulum membranes in mammalian cells.
Cell death and differentiation 2000;7(7):666-74.
1999: Takahiro Gotow; Jean-Francois Leterrier; Yoshiyuki Ohsawa; Tsuyoshi Watanabe; K Isahara; R Shibata; K Ikenaka; Yasuo Uchiyama
Abnormal expression of neurofilament proteins in dysmyelinating axons located in the central nervous system of jimpy mutant mice.
The European journal of neuroscience 1999;11(11):3893-903.
1999: Koko Urase; Takashi Momoi; Eriko Fujita; K Isahara; Yasuo Uchiyama; A Tokunaga; K Nakayama; N Motoyama
Bcl-xL is a negative regulator of caspase-3 activation in immature neurons during development.
Brain research. Developmental brain research 1999;116(1):69-78.
1999: E Hamada; Toshirou Nishida; Yasuo Uchiyama; J Nakamura; K Isahara; H Kazuo; TP Huang; Takashi Momoi; Takashi Ito; Hikaru Matsuda
Activation of Kupffer cells and caspase-3 involved in rat hepatocyte apoptosis induced by endotoxin.
Journal of hepatology 1999;30(5):807-18.
1999: K Isahara; Yoshiyuki Ohsawa; Shiro Kanamori; Masahiro Shibata; Satoshi Waguri; Naoyuki Sato; Takahiro Gotow; Tsuyoshi Watanabe; Takashi Momoi; Koko Urase; Eiki Kominami; Yasuo Uchiyama
Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinases.
Neuroscience 1999;91(1):233-49.
1998: Yoshiyuki Ohsawa; K Isahara; Shiro Kanamori; Masahiro Shibata; Satoshi Kametaka; Takahiro Gotow; Tsuyoshi Watanabe; Eiki Kominami; Yasuo Uchiyama
An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins.
Archives of histology and cytology 1998;61(5):395-403.
1998: Shiro Kanamori; Satoshi Waguri; Masahiro Shibata; K Isahara; Yoshiyuki Ohsawa; Akio Konishi; Satoshi Kametaka; Tsuyoshi Watanabe; Shigeyuki Ebisu; Eiki Kominami; Yasuo Uchiyama
Overexpression of cation-dependent mannose 6-phosphate receptor prevents cell death induced by serum deprivation in PC12 cells.
Biochemical and biophysical research communications 1998;251(1):204-8.
1998: Masahiro Shibata; Shiro Kanamori; K Isahara; Yoshiyuki Ohsawa; Akio Konishi; Satoshi Kametaka; Tsuyoshi Watanabe; Shigeyuki Ebisu; K Ishido; Eiki Kominami; Yasuo Uchiyama
Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation.
Biochemical and biophysical research communications 1998;251(1):199-203.
1998: Yoriko Kouroku; Koko Urase; Eriko Fujita; K Isahara; Yoshiyuki Ohsawa; Yasuo Uchiyama; Mariko Y Momoi; Takashi Momoi
Detection of activated Caspase-3 by a cleavage site-directed antiserum during naturally occurring DRG neurons apoptosis.
Biochemical and biophysical research communications 1998;247(3):780-4.