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Yoshitaka Isaka

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Yoshitsugu Obi; Masayoshi Okumi; Hiromi Rakugi; Naotsugu Ichimaru; Yoshitaka Isaka; Jun-Ya Kaimori; Taigo Kato; Norio Nonomura; Koji Yazawa; Shiro Takahara
A single daily dose enhances the adherence to immunosuppressive treatment in kidney transplant recipients: a cross-sectional study.
Isao Matsui; Toshimi Michigami; Satoshi Mikami; Yasuyuki Nagasawa; Chikako Nakano; Tomokazu Ohnishi; Kento Okoshi; Hiromi Rakugi; Akihiro Shimomura; Yoshitsugu Takabatake; Yoshiharu Tsubakihara; Naohiko Fujii; Takayuki Hamano; Kazunori Inoue; Hirotsugu Iwatani; Jun-Ya Kaimori; Hiromi Kimura-Suda; Harumi Kitamura; Yasuo Kusunoki; Go Matsuba; Yoshitaka Isaka
Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.
Jun-Ya Kaimori; Masaki Hatanaka; Naotsugu Ichimaru; Yoshitaka Isaka; Satomi Iwai; Kagayaki Kuroda; Norio Nonomura; Yoshitsugu Obi; Masayoshi Okumi; Hiromi Rakugi; Shiro Takahara; Takumi Teratani; Hidetoshi Tsuda; Koji Yazawa; Takashi Yokawa; Eiji Kobayashi
Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors.

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2013: Yoshitsugu Obi; Masayoshi Okumi; Hiromi Rakugi; Naotsugu Ichimaru; Yoshitaka Isaka; Jun-Ya Kaimori; Taigo Kato; Norio Nonomura; Koji Yazawa; Shiro Takahara
A single daily dose enhances the adherence to immunosuppressive treatment in kidney transplant recipients: a cross-sectional study.
Clinical and experimental nephrology 2013;17(2):310-5.
2013: Isao Matsui; Toshimi Michigami; Satoshi Mikami; Yasuyuki Nagasawa; Chikako Nakano; Tomokazu Ohnishi; Kento Okoshi; Hiromi Rakugi; Akihiro Shimomura; Yoshitsugu Takabatake; Yoshiharu Tsubakihara; Naohiko Fujii; Takayuki Hamano; Kazunori Inoue; Hirotsugu Iwatani; Jun-Ya Kaimori; Hiromi Kimura-Suda; Harumi Kitamura; Yasuo Kusunoki; Go Matsuba; Yoshitaka Isaka
Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.
American journal of physiology. Renal physiology 2013;304(6):F751-60.
2013: Jun-Ya Kaimori; Masaki Hatanaka; Naotsugu Ichimaru; Yoshitaka Isaka; Satomi Iwai; Kagayaki Kuroda; Norio Nonomura; Yoshitsugu Obi; Masayoshi Okumi; Hiromi Rakugi; Shiro Takahara; Takumi Teratani; Hidetoshi Tsuda; Koji Yazawa; Takashi Yokawa; Eiji Kobayashi
Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors.
PloS one 2013;8(5):e63573.
2013: Tomonori Kimura; Yoshitsugu Takabatake; Atsushi Takahashi; Yoshitaka Isaka
Chloroquine in cancer therapy: a double-edged sword of autophagy.
Cancer research 2013;73(1):3-7.
2012: Kazunori Inoue; Yoshitaka Isaka; Yasuo Kusunoki; Isao Matsui; Chikako Nakano; Akira Nishiyama; Naohiko Fujii; Takayuki Hamano; Michinori Hirata; Akihiro Shimomura; Yoshitsugu Takabatake; Yoshiharu Tsubakihara; Hiromi Rakugi
Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.
Laboratory investigation; a journal of technical methods and pathology 2012;92(12):1686-97.
2012: Ryoichi Imamura; Yoshitaka Isaka; Jun-Ya Kaimori; Harumi Kitamura; Bruce A Molitoris; Norio Nonomura; Masayoshi Okumi; Hiromi Rakugi; Ruben M Sandoval; Toyofumi Abe; Naotsugu Ichimaru; Koji Yazawa; Shiro Takahara
A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney.
Clinical and experimental nephrology 2012;16(6):852-62.
2012: Hirotsugu Iwatani; Yasuyuki Nagasawa; Hiromi Rakugi; Tetsuo Takehara; Yoshinao Wada; Ryohei Yamamoto; Hideki Iijima; Enyu Imai; Takahiro Inoue; Yoshitaka Isaka
Quantitative change of IgA hinge O-glycan composition is a novel marker of therapeutic responses of IgA nephropathy.
Biochemical and biophysical research communications 2012;428(3):339-42.
2012: Hidetoshi Tsuda; Jun-Ya Kaimori; Noritaka Kawada; Harumi Kitamura; Toshiki Moriyama; Hiromi Rakugi; Shiro Takahara; Yoshitaka Isaka
Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress.
Biochemical and biophysical research communications 2012;427(2):266-72.
2012: Yoshitsugu Obi; Masayoshi Okumi; Hiromi Rakugi; Shiro Takahara; Kodo Tomida; Yoshiharu Tsubakihara; Koji Yazawa; Naohiko Fujii; Takayuki Hamano; Naotsugu Ichimaru; Jun-Ya Kaimori; Yukito Kokado; Isao Matsui; Norio Nonomura; Yoshitaka Isaka
Orally active vitamin d for potential chemoprevention of posttransplant malignancy.
Cancer prevention research (Philadelphia, Pa.) 2012;5(10):1229-35.
2012: Takahiro Inoue; Yoshitaka Isaka; Hirotsugu Iwatani; Tatsuya Kanto; Eiji Miyoshi; Tsunekazu Mizushima; Akira Mukai; Sachiko Nakajima; Tsutomu Nishida; Shinichiro Shinzaki; Eri Shiraishi; Michiko Tajiri; Satoshi Hiyama; Hideki Iijima; Masahiko Tsujii; Yoshinao Wada; Teruhito Yasui; Tetsuo Takehara
Deficiency of N-acetylgalactosamine in O-linked oligosaccharides of IgA is a novel biologic marker for Crohn's disease.
Inflammatory bowel diseases 2012;18(9):1723-34.
2012: Hiroki Omori; Yoshitsugu Takabatake; Yoshiyasu Ueda; Ryohei Yamamoto; Kazunori Inoue; Yoshitaka Isaka; Jyunya Kaimori; Noritaka Kawada; Isao Matsui; Toshiki Moriyama; Hiromi Rakugi
Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.
Clinical and experimental nephrology 2012;16(4):549-56.
2012: Toyofumi Abe; Naoyuki Hatayama; Yoshitaka Isaka; Jun-ya Kaimori; Yoichi Kakuta; Xiao-Kang Li; Michiya Natori; Masayoshi Okumi; Bunpei Sato; Shiro Takahara; Hidetoshi Tsuda; Koichi Tsutahara; Lin Xie; Koji Yazawa; Norio Nonomura
Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury.
Transplantation 2012;94(1):14-21.
2012: Yoshitsugu Obi; Yoshiki Suzuki; Hitomi Hama; Yoshitaka Isaka; Toshiki Moriyama
Implausible similarities in patient characteristics between two randomized controlled studies: a coincidence is unlikely.
Kidney international 2012;82(1):115-6; author reply 116-7.
2012: Chikako Nakano; Yoshitsugu Obi; Noriyuki Okada; Hiromi Rakugi; Akihiro Shimomura; Kodo Tomida; Yoshiharu Tsubakihara; Naohiko Fujii; Takayuki Hamano; Kazunori Inoue; Isao Matsui; Satoshi Mikami; Yasuyuki Nagasawa; Yoshitaka Isaka
Intact fibroblast growth factor 23 levels predict incident cardiovascular event before but not after the start of dialysis.
Bone 2012;50(6):1266-74.
2012: Masaru Horio; Naotsugu Ichimaru; Enyu Imai; Yoshitaka Isaka; Jyunya Kaimori; Hidehisa Kitada; Ryohei Hattori; Shinichi Nishi; Shiro Takahara; Kota Takahashi; Asami Takeda; Kazuhiko Tsuruya; Kazuharu Uchida; Tsuyoshi Watanabe; Yoshinari Yasuda; Seiichi Matsuo
Performance of the Japanese GFR equation in potential kidney donors.
Clinical and experimental nephrology 2012;16(3):415-20.
2012: Chikako Nakano; Yoshitsugu Obi; Noriyuki Okada; Naohiko Fujii; Takayuki Hamano; Kazunori Inoue; Yoshitaka Isaka; Isao Matsui; Satoshi Mikami; Kodo Tomida; Yoshiharu Tsubakihara; Hiromi Rakugi
Combined use of vitamin D status and FGF23 for risk stratification of renal outcome.
Clinical journal of the American Society of Nephrology : CJASN 2012;7(5):810-9.
2012: Maki Shinzawa; Tatsuya Shoji; Yoshiharu Tsubakihara; Ryohei Yamamoto; Atsushi Yamauchi; Enyu Imai; Yoshitaka Isaka; Hirotsugu Iwatani; Tetsuya Kaneko; Harumi Kitamura; Yasuyuki Nagasawa; Tomoko Namba; Yoshitsugu Obi; Noriyuki Okada; Hiromi Rakugi
Gene polymorphisms contributing to hypertension in immunoglobulin A nephropathy.
Clinical and experimental nephrology 2012;16(2):250-8.
2012: Yasuyuki Nagasawa; Hiromi Rakugi; Ryohei Yamamoto; Yoshitaka Isaka
Cigarette smoking and chronic kidney diseases.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(3):261-5.
2012: Ryohei Yamamoto; Keiko Yamauchi-Takihara; Yoshitaka Isaka; Toshihiro Ishigami; Hirotsugu Iwatani; Yasuyuki Nagasawa; Makoto Nishida; Yoshitsugu Obi; Hiromi Rakugi; Maki Shinzawa; Junya Teranishi; Toshiki Moriyama
Self-reported sleep duration and prediction of proteinuria: a retrospective cohort study.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;59(3):343-55.
2012: Atsushi Takahashi; Tamotsu Yoshimori; Yoshitsugu Takabatake; Naonobu Fujita; Yoshitaka Isaka; Jun-Ya Kaimori; Tomonori Kimura; Harumi Kitamura; Isao Matsui; Taiji Matsusaka; Tomoko Namba; Fumio Niimura; Hiromi Rakugi
Autophagy guards against cisplatin-induced acute kidney injury.
The American journal of pathology 2012;180(2):517-25.
2012: Daisuke Hayashi; Yoshitaka Isaka; Hiromi Rakugi; Kazuhiro Sentani; Koya Suzuki; Kazuo Suzuki; Atsushi Tamura; Hiroo Tanaka; Shin Watanabe; Yuji Yamazaki; Wataru Yasui; Sachiko Tsukita
Deficiency of claudin-18 causes paracellular H+ leakage, up-regulation of interleukin-1β, and atrophic gastritis in mice.
Gastroenterology 2012;142(2):292-304.
2012: Noritaka Kawada; Harumi Kitamura; Isao Matsui; Toshiki Moriyama; Yasuyuki Nagasawa; Hiromi Rakugi; Yoshitsugu Takabatake; Christopher S Wilcox; Ryohei Yamamoto; Yoshiyuki Furumatsu; Enyu Imai; Yoshitaka Isaka
Towards developing new strategies to reduce the adverse side-effects of nonsteroidal anti-inflammatory drugs.
Clinical and experimental nephrology 2012;16(1):25-9.
2012: Tomonori Kimura; Noriko Muramoto; Tomoko Namba; Yoshitsugu Obi; Hiromi Rakugi; Koichi Sasaki; Toshihiro Satoh; Akira Wada; Keiko Yasuda; Yoshitaka Isaka; Terumasa Hayashi
[Case of HIV-associated nephropathy accompanied by nephrotic syndrome and acute worsening of kidney function].
Nihon Jinzo Gakkai shi 2012;54(2):94-8.
2012: Toyofumi Abe; Naotsugu Ichimaru; Ryoichi Imamura; Yoshitaka Isaka; Yoichi Kakuta; Norio Nonomura; Masayoshi Okumi; Shiro Takahara; Hidetoshi Tsuda; Koji Yazawa; Akihiko Okuyama
Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis.
Cell transplantation 2012;21(2-3):571-80.
2011: Tomonori Kimura; Harumi Kitamura; Isao Matsui; Yasuyuki Nagasawa; Yoshitsugu Obi; Hiromi Rakugi; Yasuhiko Sakata; Maki Shinzawa; Takayuki Hamono; Kazunori Inoue; Noritaka Kawada; Yoshitaka Isaka
Effects of nicorandil on the reduction of BNP levels in patients with chronic kidney disease.
Clinical and experimental nephrology 2011;15(6):854-60.
2011: Masayoshi Okumi; Hiromi Rakugi; Toyofumi Abe; Naotsugu Ichimaru; Ryoichi Imamura; Yoshitaka Isaka; Noritaka Kawada; Harumi Kitamura; Yasuyuki Kojima; Yukito Kokado; Toshiki Moriyama; Norio Nonomura; Shiro Takahara
Safety and efficacy of administering the maximal dose of candesartan in renal transplant recipients.
Clinical and experimental nephrology 2011;15(6):907-15.
2011: Yoshitaka Isaka; Tomonori Kimura; Yoshitsugu Takabatake
The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells.
Autophagy 2011;7(9):1085-7.
2011: Takayuki Hamano; Naohiko Fujii; Isao Matsui; Chikako Nakano; Kazunori Inoue; Kodo Tomida; Satoshi Mikami; Noriyuki Okada; Yoshiharu Tsubakihara; Hiromi Rakugi; Yoshitaka Isaka
Guideline-practice gap in the management of predialysis chronic kidney disease mineral bone disorder in Japan.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2011;15 Suppl 1():2-8.
2011: Tomonori Kimura; Yoshitsugu Takabatake; Atsushi Takahashi; Jun-Ya Kaimori; Isao Matsui; Tomoko Namba; Harumi Kitamura; Fumio Niimura; Taiji Matsusaka; Tomoyoshi Soga; Hiromi Rakugi; Yoshitaka Isaka
Autophagy protects the proximal tubule from degeneration and acute ischemic injury.
Journal of the American Society of Nephrology : JASN 2011;22(5):902-13.
2011: Yoichi Kakuta; Masayoshi Okumi; Yoshitaka Isaka; Koichi Tsutahara; Toyofumi Abe; Koji Yazawa; Naotsugu Ichimaru; Kazuaki Matsumura; Suong-Hyu Hyon; Shiro Takahara; Norio Nonomura
Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration.
Transplant international : official journal of the European Society for Organ Transplantation 2011;24(5):514-22.
2011: Toyofumi Abe; Naotsugu Ichimaru; Ryoichi Imamura; Yoshitaka Isaka; Yoichi Kakuta; Yukito Kokado; Masayoshi Okumi; Shiro Takahara; Akihiko Okuyama
Long-term outcome of pediatric renal transplantation: a single center experience.
Clinical transplantation 2011;25(3):388-94.
2011: Kenro Miyasato; Yoshitsugu Takabatake; Junya Kaimori; Tomonori Kimura; Harumi Kitamura; Hiroshi Kawachi; Xiao-Kang Li; Thomas Hünig; Shiro Takahara; Hiromi Rakugi; Yoshitaka Isaka
CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.
Clinical and experimental nephrology 2011;15(1):50-7.
2011: Hirotsugu Iwatani; Yasuyuki Nagasawa; Hiroshi Nojima; Daisuke Okuzaki; Hiromi Rakugi; Ryohei Yamamoto; Arata Horii; Kenichiro Iio; Enyu Imai; Hidenori Inohara; Yoshitaka Isaka
Microarray analysis of tonsils of IgA nephropathy patients.
Advances in oto-rhino-laryngology 2011;72():75-8.
2011: Yoshiyuki Furumatsu; Yasuyuki Nagasawa; Tatsuya Shoji; Ryohei Yamamoto; Kenichiro Iio; Isao Matsui; Yoshitsugu Takabatake; Jun-Ya Kaimori; Hirotsugu Iwatani; Tetsuya Kaneko; Yoshiharu Tsubakihara; Enyu Imai; Yoshitaka Isaka; Hiromi Rakugi
Urinary type IV collagen in nondiabetic kidney disease.
Nephron. Clinical practice 2011;117(2):c160-6.
2010: Yoshiyasu Ueda; Hisako Kayama; Seong Gyu Jeon; Takashi Kusu; Yoshitaka Isaka; Hiromi Rakugi; Masahiro Yamamoto; Kiyoshi Takeda
Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10.
International immunology 2010;22(12):953-62.
2010: Takayuki Hamano; Isao Matsui; Satoshi Mikami; Kodo Tomida; Naohiko Fujii; Enyu Imai; Hiromi Rakugi; Yoshitaka Isaka
Fetuin-mineral complex reflects extraosseous calcification stress in CKD.
Journal of the American Society of Nephrology : JASN 2010;21(11):1998-2007.
2010: Ryohei Yamamoto; Yasuyuki Nagasawa; Tatsuya Shoji; Hirotsugu Iwatani; Takayuki Hamano; Noritaka Kawada; Kazunori Inoue; Takuya Uehata; Tetsuya Kaneko; Noriyuki Okada; Toshiki Moriyama; Masaru Horio; A Yamauchi; Yoshiharu Tsubakihara; Enyu Imai; Hiromi Rakugi; Yoshitaka Isaka
Cigarette smoking and progression of IgA nephropathy.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;56(2):313-24.
2010: Tomonori Kimura; Ken-ichiro Iio; Enyu Imai; Hiromi Rakugi; Yoshitaka Isaka; Terumasa Hayashi
Exercise-induced acute kidney injury with reversible posterior leukoencephalopathy syndrome.
Clinical and experimental nephrology 2010;14(2):173-5.
2010: Kenichiro Iio; Yasuyuki Nagasawa; Hirotsugu Iwatani; Ryohei Yamamoto; Arata Horii; Daisuke Okuzaki; Yoshiyuki Furumatsu; Hidenori Inohara; Hiroshi Nojima; Enyu Imai; Yoshitaka Isaka; Hiromi Rakugi
Microarray analysis of tonsils in immunoglobulin A nephropathy patients.
Biochemical and biophysical research communications 2010;393(4):565-70.
2010: Yoichi Kakuta; Masayoshi Okumi; Naotsugu Ichimaru; Toyofumi Abe; Norio Nonomura; Akihiko Okuyama; Yasuyuki Kojima; Yoshitaka Isaka; Shiro Takahara; Enyu Imai; Masaru Horio
Utility of the Japanese GFR estimation equation for evaluating potential donor kidney function.
Clinical and experimental nephrology 2010;14(1):63-7.
2010: Ryoichi Imamura; Yoshitaka Isaka; Ruben M Sandoval; Asaf Ori; Swetlana Adamsky; Elena Feinstein; Bruce A Molitoris; Shiro Takahara
Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models.
Cell transplantation 2010;19(12):1659-70.
2010: Yusuke Kitazawa; Xiao-Kang Li; Zhong Liu; Hiromitsu Kimura; Yoshitaka Isaka; Thomas Hünig; Shiro Takahara
Prevention of graft-versus-host diseases by in vivo supCD28mAb-expanded antigen-specific nTreg cells.
Cell transplantation 2010;19(6):765-74.
2010: Toyofumi Abe; Naotsugu Ichimaru; Yukito Kokado; Tetsuo Maeda; Yoichi Kakuta; Masayoshi Okumi; Ryoichi Imamura; Norio Nonomura; Yoshitaka Isaka; Shiro Takahara; Akihiko Okuyama
Post-transplant lymphoproliferative disorder following renal transplantation: a single-center experience over 40 years.
International journal of urology : official journal of the Japanese Urological Association 2010;17(1):48-54.
2009: Hidetoshi Tsuda; Yoshitaka Isaka; Shiro Takahara; Masaru Horio
Discrepancy between serum levels of low molecular weight proteins in acute kidney injury model rats with bilateral ureteral obstruction and bilateral nephrectomy.
Clinical and experimental nephrology 2009;13(6):567-70.
2009: Hirotaka Tanaka; Takayuki Hamano; Naohiko Fujii; Kodo Tomida; Isao Matsui; Satoshi Mikami; Yasuyuki Nagasawa; Takahito Ito; Toshiki Moriyama; Masaru Horio; Enyu Imai; Yoshitaka Isaka; Hiromi Rakugi
The impact of diabetes mellitus on vitamin D metabolism in predialysis patients.
Bone 2009;45(5):949-55.
2009: Tatsukata Kawagoe; Osamu Takeuchi; Yoshitsugu Takabatake; Hiroki Kato; Yoshitaka Isaka; Tohru Tsujimura; Shizuo Akira
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.
Nature immunology 2009;10(9):965-72.
2009: Yoshitsugu Takabatake; Tatsuki Sugiyama; Hiroshi Kohara; Taiji Matsusaka; Hidetake Kurihara; Pandelakis Koni; Yasuyuki Nagasawa; Takayuki Hamano; Isao Matsui; Noritaka Kawada; Enyu Imai; Takashi Nagasawa; Hiromi Rakugi; Yoshitaka Isaka
The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.
Journal of the American Society of Nephrology : JASN 2009;20(8):1714-23.
2009: Noritaka Kawada; Toshiki Moriyama; Naotsugu Ichimaru; Ryoichi Imamura; Isao Matsui; Yoshitsugu Takabatake; Yasuyuki Nagasawa; Yoshitaka Isaka; Yasuyuki Kojima; Yukito Kokado; Hiromi Rakugi; Enyu Imai; Shiro Takahara
Negative effects of anemia on quality of life and its improvement by complete correction of anemia by administration of recombinant human erythropoietin in posttransplant patients.
Clinical and experimental nephrology 2009;13(4):355-60.
2009: Isao Matsui; Takayuki Hamano; Kodo Tomida; Kazunori Inoue; Yoshitsugu Takabatake; Yasuyuki Nagasawa; Noritaka Kawada; Takahito Ito; Hiroshi Kawachi; Hiromi Rakugi; Enyu Imai; Yoshitaka Isaka
Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(8):2354-61.
2009: Takayuki Hamano; Kodo Tomida; Satoshi Mikami; Isao Matsui; Naohiko Fujii; Enyu Imai; Hiromi Rakugi; Yoshitaka Isaka
Usefulness of bone resorption markers in hemodialysis patients.
Bone 2009;45 Suppl 1():S19-25.
2009: Isao Matsui; Takayuki Hamano; Satoshi Mikami; Naohiko Fujii; Yoshitsugu Takabatake; Yasuyuki Nagasawa; Noritaka Kawada; Takahito Ito; Hiromi Rakugi; Enyu Imai; Yoshitaka Isaka
Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure.
Kidney international 2009;75(9):915-28.
2009: Kodo Tomida; Takayuki Hamano; Satoshi Mikami; Naohiko Fujii; Noriyuki Okada; Isao Matsui; Yasuyuki Nagasawa; Toshiki Moriyama; Takahito Ito; Enyu Imai; Yoshitaka Isaka; Hiromi Rakugi
Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients.
Bone 2009;44(4):678-83.
2009: Yoshiyasu Ueda; Masayo Aizawa; Atsushi Takahashi; Masamitsu Fujii; Yoshitaka Isaka
Exaggerated compensatory response to acute respiratory alkalosis in panic disorder is induced by increased lactic acid production.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(3):825-8.
2009: Hirotaka Tanaka; Yasuyuki Nagasawa; Isao Matsui; Takayuki Hamano; Hirotsugu Iwatani; Noritaka Kawada; Masaru Horio; Takahito Ito; Yoshitaka Isaka; Enyu Imai
Pharmacokinetics of olmesartan medoxomil in hemodialysis patients: little effect of dialysis upon its pharmacokinetics.
Clinical and experimental nephrology 2009;13(1):61-5.
2009: Yusuke Kitazawa; Masayuki Fujino; Xiao-Kang Li; Lin Xie; Naotsugu Ichimaru; Masayoshi Okumi; Norio Nonomura; Akira Tsujimura; Yoshitaka Isaka; Hiromitsu Kimura; Thomas Hünig; Shiro Takahara
Superagonist CD28 antibody preferentially expanded Foxp3-expressing nTreg cells and prevented graft-versus-host diseases.
Cell transplantation 2009;18(5):627-37.
2009: Ryohei Yamamoto; Yasuyuki Nagasawa; Shigeru Marubashi; Yoshiyuki Furumatsu; Hirotsugu Iwatani; Kenichiro Iio; Isao Matsui; Keizo Dono; Enyu Imai; Morito Monden; Yoshitaka Isaka
Early plasma exchange for progressive liver failure in recipients of adult-to-adult living-related liver transplants.
Blood purification 2009;28(1):40-6.
2009: Yoshitaka Isaka; C Suzuki; T Abe; Masayoshi Okumi; Naotsugu Ichimaru; Ryoichi Imamura; Y Kakuta; I Matsui; Yoshitsugu Takabatake; H Rakugi; Shigeomi Shimizu; Shiro Takahara
Bcl-2 protects tubular epithelial cells from ischemia/reperfusion injury by dual mechanisms.
Transplantation proceedings 2009;41(1):52-4.
2009: Yoshitsugu Takabatake; Yoshitaka Isaka; Enyu Imai
In vivo transfer of small interfering RNA or small hairpin RNA targeting glomeruli.
Methods in molecular biology (Clifton, N.J.) 2009;466():251-63.
2008: Yoshitaka Isaka; Enyu Imai; Shiro Takahara; Hiromi Rakugi
Oligonucleotidic therapeutics.
Expert opinion on drug discovery 2008;3(9):991-6.
2008: Toyofumi Abe; Naotsugu Ichimaru; Masayoshi Okumi; Ryoichi Imamura; Yoshitaka Isaka; Shiro Takahara; Yukito Kokado; Akihiko Okuyama
Pregnancy after renal transplantation: a single-center experience.
International journal of urology : official journal of the Japanese Urological Association 2008;15(7):587-92.
2008: Satoshi Mikami; Takayuki Hamano; Naohiko Fujii; Yasuyuki Nagasawa; Yoshitaka Isaka; Toshiki Moriyama; Munehide Matsuhisa; Takahito Ito; Enyu Imai; Masatsugu Hori
Serum osteoprotegerin as a screening tool for coronary artery calcification score in diabetic pre-dialysis patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(6):1163-70.
2008: Naotsugu Ichimaru; Y Kakuta; T Abe; Masayoshi Okumi; R Imamura; Yoshitaka Isaka; Norio Nonomura; Y Kojima; Akihiko Okuyama; Shiro Takahara
Treatment adherence in renal transplant recipients: a questionnaire survey on immunosuppressants.
Transplantation proceedings 2008;40(5):1362-5.
2008: H Kitamura; Yoshitaka Isaka; Yoshitsugu Takabatake; Ryoichi Imamura; Chigure Suzuki; Shiro Takahara; Enyu Imai
Nonerythropoietic derivative of erythropoietin protects against tubulointerstitial injury in a unilateral ureteral obstruction model.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(5):1521-8.
2008: Chigure Suzuki; Yoshitaka Isaka; Yoshitsugu Takabatake; Hirotaka Tanaka; Masato Koike; Masahiro Shibata; Yasuo Uchiyama; Shiro Takahara; Enyu Imai
Participation of autophagy in renal ischemia/reperfusion injury.
Biochemical and biophysical research communications 2008;368(1):100-6.
2008: Yoshitsugu Takabatake; Yoshitaka Isaka; Enyu Imai
Renal artery injection for delivery of biological materials to the glomerulus.
Nephrology (Carlton, Vic.) 2008;13(1):23-6.
2008: Chigure Suzuki; Yoshitaka Isaka; Shigeomi Shimizu; Yoshihide Tsujimoto; Yoshitsugu Takabatake; Takahito Ito; Shiro Takahara; Enyu Imai
Bcl-2 protects tubular epithelial cells from ischemia reperfusion injury by inhibiting apoptosis.
Cell transplantation 2008;17(1-2):223-9.
2008: Daoxin Zhang; Yoshitaka Isaka; Ryoichi Imamura; Naotsugu Ichimaru; Yi Shi; Enyu Imai; Ye Tian; Aiji Ohtsuka; Shiro Takahara
Glycocalyx damage estimated using colloidal iron staining.
Cell transplantation 2008;17(1-2):159-63.
2008: Ryoichi Imamura; Masayoshi Okumi; Yoshitaka Isaka; Naotsugu Ichimaru; Toshiki Moriyama; Enyu Imai; Norio Nonomura; Shiro Takahara; Akihiko Okuyama
Carbamylated erythropoietin improves angiogenesis and protects the kidneys from ischemia-reperfusion injury.
Cell transplantation 2008;17(1-2):135-41.
2008: Yoshitaka Isaka; Shiro Takahara; Enyu Imai
Chronic deteriorating renal function and renal fibrosis.
Contributions to nephrology 2008;159():109-21.
2007: Feng Xue; Yoshitaka Isaka; Terumi Takahara; Ryoichi Imamura; Chigure Suzuki; Naotsugu Ichimaru; Paolo Michieli; Shiro Takahara
HGF-MSP chimera protects kidneys from ischemia-reperfusion injury.
Biochemical and biophysical research communications 2007;363(2):451-6.
2007: Yoshitsugu Takabatake; Yoshitaka Isaka; Masayuki Mizui; Hiroshi Kawachi; Shiro Takahara; Enyu Imai
Chemically modified siRNA prolonged RNA interference in renal disease.
Biochemical and biophysical research communications 2007;363(2):432-7.
2007: Yoshitaka Isaka; Enyu Imai
Electroporation-mediated gene therapy.
Expert opinion on drug delivery 2007;4(5):561-71.
2007: Ryoichi Imamura; Toshiki Moriyama; Yoshitaka Isaka; Yukiomi Namba; Naotsugu Ichimaru; Shiro Takahara; Akihiko Okuyama
Erythropoietin protects the kidneys against ischemia reperfusion injury by activating hypoxia inducible factor-1alpha.
Transplantation 2007;83(10):1371-9.
2007: Tetsuya Imao; Naotsugu Ichimaru; Shiro Takahara; Yukito Kokado; Masayoshi Okumi; Ryoichi Imamura; Yukiomi Namba; Yoshitaka Isaka; Norio Nonomura; Akihiko Okuyama
Risk factors for malignancy in Japanese renal transplant recipients.
Cancer 2007;109(10):2109-15.
2007: Yoshitaka Isaka
DNAzymes as potential therapeutic molecules.
Current opinion in molecular therapeutics 2007;9(2):132-6.
2007: Ryoichi Imamura; Yoshitaka Isaka; Naotsugu Ichimaru; Shiro Takahara; Akihiko Okuyama
Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis.
Biochemical and biophysical research communications 2007;353(3):786-92.
2006: Yoshitaka Isaka
Gene therapy targeting kidney diseases: routes and vehicles.
Clinical and experimental nephrology 2006;10(4):229-35.
2006: Naohiko Fujii; Yoshitaka Isaka; Yoshitsugu Takabatake; Masayuki Mizui; Chigure Suzuki; Shiro Takahara; Takahito Ito; Enyu Imai
Targeting of interstitial cells using a simple gene-transfer strategy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(10):2745-53.
2006: Masayuki Mizui; Yoshitaka Isaka; Yoshitsugu Takabatake; Y Sato; Hiroshi Kawachi; Fujio Shimizu; Shiro Takahara; Takashi Ito; Enyu Imai
Transcription factor Ets-1 is essential for mesangial matrix remodeling.
Kidney international 2006;70(2):298-305.
2006: Ryoichi Imamura; Shin Ishiguro; Yi Shi; Yukiomi Namba; Naotsugu Ichimaru; Yoshitaka Isaka; Shiro Takahara; Akihiko Okuyama
ABO-incompatible kidney transplantation with anti-CD20 monoclonal antibodies, intravenous immunoglobulin and plasmapheresis without splenectomy: a case report.
Xenotransplantation 2006;13(2):133-5.
2006: Yoshitaka Isaka; Yoshitsugu Takabatake; Enyu Imai
[RNAi gene therapy for kidney disease].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 2():659-61.
2006: Yukiomi Namba; Kazumasa Oka; Toshiki Moriyama; Masahiro Kyo; Ryoichi Imamura; Yi Shi; Naotsugu Ichimaru; Yoshitaka Isaka; Shiro Takahara; Akihiko Okuyama
Incidence of positive C4d deposition in long-term survival cases over 10 yr after renal transplantation.
Clinical transplantation 2006;20 Suppl 15():20-5.
2005: Naohiko Fujii; Takayuki Hamano; Yoshitaka Isaka; Takahito Ito; Enyu Imai
[Risedronate: a possible treatment for extraosseous calcification].
Clinical calcium 2005;15 Suppl 1():75-8; discussion 78-9.
2005: Yoshitsugu Takabatake; Yoshitaka Isaka; Masayuki Mizui; Hiroshi Kawachi; Fujio Shimizu; Takashi Ito; Masatsugu Hori; Enyu Imai
Exploring RNA interference as a therapeutic strategy for renal disease.
Gene therapy 2005;12(12):965-73.
2005: Yoshitaka Isaka; Kiyofumi Yamada; Yoshitsugu Takabatake; Masayuki Mizui; M Miura-Tsujie; Naotsugu Ichimaru; Koji Yazawa; R Utsugi; Akihiko Okuyama; Masatsugu Hori; Enyu Imai; Shiro Takahara
Electroporation-mediated HGF gene transfection protected the kidney against graft injury.
Gene therapy 2005;12(10):815-20.
2004: Yoshitaka Isaka; Hiroyuki Nakamura; Masayuki Mizui; Yoshitsugu Takabatake; Masaru Horio; Hiroshi Kawachi; Fujio Shimizu; Enyu Imai; Masatsugu Hori
DNAzyme for TGF-beta suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 2004;66(2):586-90.
2004: Masayuki Mizui; Yoshitaka Isaka; Yoshitsugu Takabatake; Sinya Mizuno; Toshikazu Nakamura; Takahito Ito; Enyu Imai; Masatsugu Hori
Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity.
Kidney international 2004;65(6):2041-53.
2004: Enyu Imai; Yoshitsugu Takabatake; Masayuki Mizui; Yoshitaka Isaka
Gene therapy in renal diseases.
Kidney international 2004;65(5):1551-5.
2004: Koji Yazawa; Yoshitaka Isaka; Shiro Takahara; Enyu Imai; Naotsugu Ichimaru; Yi Shi; Yukiomi Namba; Akihiko Okuyama
Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(4):812-6.
2004: Enyu Imai; Yoshitaka Isaka
Perspectives for gene therapy in renal diseases.
Internal medicine (Tokyo, Japan) 2004;43(2):85-96.
2004: Akira Suzuki; Hirotsugu Iwatani; Takahito Ito; Enyu Imai; Masaru Okabe; Hiroyuki Nakamura; Yoshitaka Isaka; Masaya Yamato; Masatsugu Hori
Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells.
Kidney international 2004;65(1):15-24.
2003: Christoph Daniel; Yoshitsugu Takabatake; Masayuki Mizui; Yoshitaka Isaka; Hiroshi Kawashi; Harald Rupprecht; Enyu Imai; Christian Hugo
Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo.
The American journal of pathology 2003;163(3):1185-92.
2003: Enyu Imai; Masaru Takenaka; Yoshitaka Isaka; Toshiki Moriyama; Yoshitaka Akagi; Jyunji Kakuchi; Takashi Fujii; Takahito Ito; Masatsugu Hori; Masaru Horio; Tatsuya Syoji; Yoshiharu Tsubakihara
Carbonic adsorbent AST-120 retards progression of renal failure by additive effect with ACEI and protein restriction diet.
Clinical and experimental nephrology 2003;7(2):113-9.
2003: Shogo Kobayashi; Keizo Dono; Shiro Takahara; Yoshitaka Isaka; Enyu Imai; Lu Zhenhui; Hiroaki Nagano; Kato Tomoaki; Koji Umeshita; Shoji Nakamori; Masato Sakon; Morito Monden
Electroporation-mediated ex vivo gene transfer into graft not requiring injection pressure in orthotopic liver transplantation.
The journal of gene medicine 2003;5(6):510-7.
2003: Marina Carl; Yoshitaka Akagi; Sven Weidner; Yoshitaka Isaka; Enyu Imai; Harald D Rupprecht
Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis.
Kidney international 2003;63(4):1302-12.
2003: Shogo Kobayashi; Keizo Dono; Toshiyuki Tanaka; Shiro Takahara; Yoshitaka Isaka; Enyu Imai; Hiroaki Nagano; Kato Tomoaki; Koji Umeshita; Shoji Nakamori; Masato Sakon; Morito Monden
Gene transfer into the liver by plasmid injection into the portal vein combined with electroporation.
The journal of gene medicine 2003;5(3):201-8.
2002: Hideji Nakamura; Yoshitaka Isaka; M Tsujie; Harald D Rupprecht; Yoshitaka Akagi; N Ueda; Enyu Imai; Masatsugu Hori
Introduction of DNA enzyme for Egr-1 into tubulointerstitial fibroblasts by electroporation reduced interstitial alpha-smooth muscle actin expression and fibrosis in unilateral ureteral obstruction (UUO) rats.
Gene therapy 2002;9(8):495-502.
2002: Enyu Imai; Yoshitaka Isaka
Gene electrotransfer: potential for gene therapy of renal diseases.
Kidney international 2002;61(1 Suppl):S37-41.
2002: Enyu Imai; Yoshitaka Isaka
Targeting growth factors to the kidney: myth or reality?
Current opinion in nephrology and hypertension 2002;11(1):49-57.
2001: Hideji Nakamura; Yoshitaka Isaka; M Tsujie; Yoshitaka Akagi; T Sudo; N Ohno; Enyu Imai; Masatsugu Hori
Electroporation-mediated PDGF receptor-IgG chimera gene transfer ameliorates experimental glomerulonephritis.
Kidney international 2001;59(6):2134-45.
2001: M Tsujie; Yoshitaka Isaka; Hideji Nakamura; Enyu Imai; Masatsugu Hori
Electroporation-mediated gene transfer that targets glomeruli.
Journal of the American Society of Nephrology : JASN 2001;12(5):949-54.
2001: M Tsujie; Yoshitaka Isaka; Hideji Nakamura; Yasufumi Kaneda; Enyu Imai; Masatsugu Hori
Prolonged transgene expression in glomeruli using an EBV replicon vector system combined with HVJ liposomes.
Kidney international 2001;59(4):1390-6.
2001: Yoshitaka Isaka; Enyu Imai
Future strategy: gene therapy for diabetic nephropathy.
Contributions to nephrology 2001;(134):127-32.
2001: Enyu Imai; M Takenaka; Takahito Ito; Yoshitaka Isaka; Toshiki Moriyama; Masatsugu Hori
[Gene therapy and tissue engineering in nephrology and renal transplantation].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(1):65-71.
2000: Yoshitaka Isaka; M Tsujie; Y Ando; Hideji Nakamura; Yasufumi Kaneda; Enyu Imai; Masatsugu Hori
Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction.
Kidney international 2000;58(5):1885-92.
2000: M Tsujie; Yoshitaka Isaka; Y Ando; Yoshitaka Akagi; Yasufumi Kaneda; N Ueda; Enyu Imai; Masatsugu Hori
Gene transfer targeting interstitial fibroblasts by the artificial viral envelope-type hemagglutinating virus of Japan liposome method.
Kidney international 2000;57(5):1973-80.
1999: Y Ando; Toshiki Moriyama; Kazumasa Oka; K Takatsuji; M Miyazaki; Yoshitaka Akagi; Noritaka Kawada; Yoshitaka Isaka; M Izumi; K Yokoyama; A Yamauchi; Masaru Horio; A Ando; N Ueda; Kenji Sobue; Enyu Imai; Masatsugu Hori
Enhanced interstitial expression of caldesmon in IgA nephropathy and its suppression by glucocorticoid-heparin therapy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(6):1408-17.
1999: Yoshitaka Isaka; Yoshitaka Akagi; Y Ando; M Tsujie; T Sudo; N Ohno; Wayne A Border; Nancy A Noble; Yasufumi Kaneda; Masatsugu Hori; Enyu Imai
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1999;55(2):465-75.
1999: Enyu Imai; Yoshitaka Isaka
New paradigm of gene therapy: skeletal-muscle-targeting gene therapy for kidney disease.
Nephron 1999;83(4):296-300.
1999: Yoshitaka Isaka; Yoshitaka Akagi; Y Ando; M Tsujie; Enyu Imai
Cytokines and glomerulosclerosis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14 Suppl 1():30-2.
1999: Enyu Imai; Yoshitaka Akagi; Yoshitaka Isaka; M Ikawa; M Takenaka; Masatsugu Hori; Masaru Okabe
Glowing podocytes in living mouse: transgenic mouse carrying a podocyte-specific promoter.
Experimental nephrology 1999;7(1):63-6.
1998: Y Ando; Toshiki Moriyama; M Miyazaki; Yoshitaka Akagi; Noritaka Kawada; Yoshitaka Isaka; M Izumi; K Yokoyama; A Yamauchi; Masaru Horio; A Ando; N Ueda; Kenji Sobue; Enyu Imai; Masatsugu Hori
Enhanced glomerular expression of caldesmon in IgA nephropathy and its suppression by glucocorticoid-heparin therapy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1998;13(5):1168-75.
1998: Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda; Enyu Imai
The HVJ liposome method.
Experimental nephrology 1998;6(2):144-7.
1998: Enyu Imai; Yoshitaka Isaka
Strategies of gene transfer to the kidney.
Kidney international 1998;53(2):264-72.
1998: Enyu Imai; Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda; Masatsugu Hori
Gene transfer and kidney disease.
Journal of nephrology 1998;11(1):16-9.
1997: Yoshitaka Akagi; Yoshitaka Isaka; A Akagi; Masahito Ikawa; Masaru Takenaka; Toshiki Moriyama; A Yamauchi; Masaru Horio; N Ueda; Masaru Okabe; Enyu Imai
Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo.
Kidney international 1997;51(4):1265-9.
1997: Enyu Imai; Yoshitaka Isaka; Yoshitaka Akagi; Yasufumi Kaneda
Gene transfer into the glomerulus by the hemagglutinating virus of Japan-liposome method.
Experimental nephrology 1997;5(2):112-7.
1996: Yoshitaka Akagi; Yoshitaka Isaka; M Arai; T Kaneko; Masaru Takenaka; Toshiki Moriyama; Yasufumi Kaneda; A Ando; Yoshimasa Orita; T Kamada; N Ueda; Enyu Imai
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Kidney international 1996;50(1):148-55.
1996: Enyu Imai; Yoshitaka Isaka; Y Akagi; M Arai; T Moriyama; M Takenaka; T Kaneko; M Horio; A Ando; Yoshimasa Orita; Yasufumi Kaneda; N Ueda; T Kamada
Application of antisense oligodeoxynucleotides (ODNs) for the intervention of kidney disease. Antisense ODNs for transforming growth factor-beta-suppressed glomerulosclerosis in experimental glomerulonephritis.
Contributions to nephrology 1996;118():86-93.
1995: M Arai; A Wada; Yoshitaka Isaka; Yoshitaka Akagi; T Sugiura; M Miyazaki; Toshiki Moriyama; Yasufumi Kaneda; K Naruse; M Naruse
In vivo transfection of genes for renin and angiotensinogen into the glomerular cells induced phenotypic change of the mesangial cells and glomerular sclerosis.
Biochemical and biophysical research communications 1995;206(2):525-32.
1994: Enyu Imai; Yoshitaka Isaka; Y Fujiwara; Yasufumi Kaneda; T Kamada; N Ueda
Introduction of a foreign gene into the kidney in vivo: development of glomerulosclerosis by the transfection of genes for PDGF and TGF-beta.
Contributions to nephrology 1994;107():205-15.
1993: Yoshitaka Isaka; Y Fujiwara; N Ueda; Yasufumi Kaneda; T Kamada; Enyu Imai
Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.
The Journal of clinical investigation 1993;92(6):2597-601.
1993: T Inoue; Y Yoshida; Yoshitaka Isaka; K Tagawa
Isolation of mitochondrial cyclophilin from bovine heart.
Biochemical and biophysical research communications 1993;190(3):857-63.
1992: Yoshitaka Isaka; Y Fujiwara; S Yamamoto; S Ochi; S Shin; T Inoue; K Tagawa; T Kamada; N Ueda
Modified plasma clearance technique using nonradioactive iothalamate for measuring GFR.
Kidney international 1992;42(4):1006-11.
1992: Yoshitaka Isaka; S Yamamoto; Y Fujiwara; S H Shin; S Ochi; T Kamada; N Ueda
[A new analytical method for simultaneous measurement of iothalamate and iohexol].
Rinsho byori. The Japanese journal of clinical pathology 1992;40(7):703-7.