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Mario Isas

Research Profile

Chemicals & Drugs

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Electron Spin Resonance Spectroscopy

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Publications

TOP 3
Charles W Bugg; Torsten Fischer; J Mario Isas; Paul H Patterson; Ralf Langen
Structural features and domain organization of huntingtin fibrils.
Sahar Bedrood; Ian S Haworth; Balachandra G Hegde; J Mario Isas; Ulrich Baxa; Yiyu Li; Ralf Langen
Fibril structure of human islet amyloid polypeptide.
Andrew W Woodham; Ralf Langen; Adam B Raff; Joseph G Skeate; Mark R Ambroso; Heike E Brand; Diane M Da Silva; J Mario Isas; W Martin Kast
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection.

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All Publications

2012: Charles W Bugg; Torsten Fischer; J Mario Isas; Paul H Patterson; Ralf Langen
Structural features and domain organization of huntingtin fibrils.
The Journal of biological chemistry 2012;287(38):31739-46.
2012: Sahar Bedrood; Ian S Haworth; Balachandra G Hegde; J Mario Isas; Ulrich Baxa; Yiyu Li; Ralf Langen
Fibril structure of human islet amyloid polypeptide.
The Journal of biological chemistry 2012;287(8):5235-41.
2012: Andrew W Woodham; Ralf Langen; Adam B Raff; Joseph G Skeate; Mark R Ambroso; Heike E Brand; Diane M Da Silva; J Mario Isas; W Martin Kast
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection.
PloS one 2012;7(8):e43519.
2010: Jobin Varkey; J Mario Isas; Naoko Mizuno; Martin Borch Jensen; Vikram Kjøller Bhatia; Christine C Jao; Jitka Petrlova; John C Voss; Dimitrios G Stamou; Alasdair C Steven; Ralf Langen
Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins.
The Journal of biological chemistry 2010;285(42):32486-93.
2010: J Mario Isas; Volker Luibl; Lincoln V Johnson; Rakez Kayed; Ronald Wetzel; Charles G Glabe; Ralf Langen; Jeannie Chen
Soluble and mature amyloid fibrils in drusen deposits.
Investigative ophthalmology & visual science 2010;51(3):1304-10.
2010: Jessica W Wu; Leonid Breydo; J Mario Isas; Jerome Lee; Yurii G Kuznetsov; Ralf Langen; Charles G Glabe
Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation.
The Journal of biological chemistry 2010;285(9):6071-9.
2008: Ryan T Hamilton; Liana Asatryan; Jon Nilsen; J Mario Isas; Timothy K Gallaher; Tatsuya Sawamura; Tzung K Hsiai
LDL protein nitration: implication for LDL protein unfolding.
Archives of biochemistry and biophysics 2008;479(1):1-14.
2008: Thuzar M Shin; J Mario Isas; Chia-Ling Hsieh; Rakez Kayed; Charles G Glabe; Ralf Langen; Jeannie Chen
Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin.
Molecular neurodegeneration 2008;3():16.
2006: Volker Luibl; J Mario Isas; Rakez Kayed; Charles G Glabe; Ralf Langen; Jeannie Chen
Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers.
The Journal of clinical investigation 2006;116(2):378-85.
2006: Balachandra G Hegde; J Mario Isas; Guido A Zampighi; Harry T Haigler; Ralf Langen
A novel calcium-independent peripheral membrane-bound form of annexin B12.
Biochemistry 2006;45(3):934-42.
2005: J Mario Isas; Yujin E Kim; Christine C Jao; Prabhavati B Hegde; Harry T Haigler; Ralf Langen
Calcium- and membrane-induced changes in the structure and dynamics of three helical hairpins in annexin B12.
Biochemistry 2005;44(50):16435-44.
2005: Yujin E Kim; J Mario Isas; Harry T Haigler; Ralf Langen
A helical hairpin region of soluble annexin B12 refolds and forms a continuous transmembrane helix at mildly acidic pH.
The Journal of biological chemistry 2005;280(37):32398-404.
2005: Darshana R Patel; J Mario Isas; Alexey S Ladokhin; Christine C Jao; Yujin E Kim; Thorsten Kirsch; Ralf Langen; Harry T Haigler
The conserved core domains of annexins A1, A2, A5, and B12 can be divided into two groups with different Ca2+-dependent membrane-binding properties.
Biochemistry 2005;44(8):2833-44.
2005: Liana Asatryan; Ryan T Hamilton; J Mario Isas; Juliana Hwang; Rakez Kayed; Alex Sevanian
LDL phospholipid hydrolysis produces modified electronegative particles with an unfolded apoB-100 protein.
Journal of lipid research 2005;46(1):115-22.
2004: J Mario Isas; Ralf Langen; Wayne L Hubbell; Harry T Haigler
Structure and dynamics of a helical hairpin that mediates calcium-dependent membrane binding of annexin B12.
The Journal of biological chemistry 2004;279(31):32492-8.
2003: Thomas Risse; Wayne L Hubbell; J Mario Isas; Harry T Haigler
Structure and dynamics of annexin 12 bound to a planar lipid bilayer.
Physical review letters 2003;91(18):188101.
2003: J Mario Isas; Darshana R Patel; Christine C Jao; Sajith A Jayasinghe; Jean-Philippe Cartailler; Harry T Haigler; Ralf Langen
Global structural changes in annexin 12. The roles of phospholipid, Ca2+, and pH.
The Journal of biological chemistry 2003;278(32):30227-34.
2002: Alexey S Ladokhin; J Mario Isas; Harry T Haigler; Stephen H White
Determining the membrane topology of proteins: insertion pathway of a transmembrane helix of annexin 12.
Biochemistry 2002;41(46):13617-26.
2002: J Mario Isas; Ralf Langen; Harry T Haigler; Wayne L Hubbell
Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study.
Biochemistry 2002;41(5):1464-73.
2001: Darshana R Patel; Christine C Jao; WS Mailliard; J Mario Isas; Ralf Langen; Harry T Haigler
Calcium-dependent binding of annexin 12 to phospholipid bilayers: stoichiometry and implications.
Biochemistry 2001;40(24):7054-60.
2000: J Mario Isas; Jean-Philippe Cartailler; Yuri Sokolov; Darshana R Patel; Ralf Langen; Hartmut Luecke; James E Hall; Harry T Haigler
Annexins V and XII insert into bilayers at mildly acidic pH and form ion channels.
Biochemistry 2000;39(11):3015-22.
1998: Ralf Langen; J Mario Isas; Wayne L Hubbell; Harry T Haigler
A transmembrane form of annexin XII detected by site-directed spin labeling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14060-5.
1998: Gabriel Vargas; J Mario Isas; Emmanuelle Fantino; J Jay Gargus; Harry T Haigler
CCG1/TAF(II)250 regulates epidermal growth factor receptor gene transcription in cell cycle mutant ts13.
Journal of cellular physiology 1998;176(3):642-7.
1998: Ralf Langen; J Mario Isas; Hartmut Luecke; Harry T Haigler; Wayne L Hubbell
Membrane-mediated assembly of annexins studied by site-directed spin labeling.
The Journal of biological chemistry 1998;273(35):22453-7.