FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

David Isenberg

Research Profile

Disorders

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Fabian Flores-Borja; David A Isenberg; Anneleen Bosma; Michael R Ehrenstein; Dorothy Ng; Venkat Reddy; Claudia Mauri
CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation.
Charis Pericleous; Paul A Brogan; Lindsey A Clarke; Ian Giles; Yiannis Ioannou; David A Isenberg; David S Latchman; Anisur Rahman
Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome.
Grainne Murphy; David A Isenberg
Connective tissue diseases: SLE-associated arthropathy: truly a benign entity?

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of David Isenberg (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Fabian Flores-Borja; David A Isenberg; Anneleen Bosma; Michael R Ehrenstein; Dorothy Ng; Venkat Reddy; Claudia Mauri
CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation.
Science translational medicine 2013;5(173):173ra23.
2013: Charis Pericleous; Paul A Brogan; Lindsey A Clarke; Ian Giles; Yiannis Ioannou; David A Isenberg; David S Latchman; Anisur Rahman
Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome.
Thrombosis and haemostasis 2013;109(1):72-8.
2012: Grainne Murphy; David A Isenberg
Connective tissue diseases: SLE-associated arthropathy: truly a benign entity?
Nature reviews. Rheumatology 2012;8(12):695-6.
2012: Jenny L McGovern; Dao X Nguyen; Clare A Notley; David A Isenberg; Claudia Mauri; Michael R Ehrenstein
Th17 cells are restrained by Treg cells via the inhibition of interleukin-6 in patients with rheumatoid arthritis responding to anti-tumor necrosis factor antibody therapy.
Arthritis and rheumatism 2012;64(10):3129-38.
2012: Mark N Lazarus; Tabitha Turner-Stokes; Konstantia-Maria Chavele; David A Isenberg; Michael R Ehrenstein
B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels.
Rheumatology (Oxford, England) 2012;51(7):1208-15.
2012: Anneleen Bosma; David A Isenberg; Elizabeth C Jury; Azza Abdel-Gadir; Claudia Mauri
Lipid-antigen presentation by CD1d(+) B cells is essential for the maintenance of invariant natural killer T cells.
Immunity 2012;36(3):477-90.
2012: Amara N Ezeonyeji; David A Isenberg
Early treatment with rituximab in newly diagnosed systemic lupus erythematosus patients: a steroid-sparing regimen.
Rheumatology (Oxford, England) 2012;51(3):476-81.
2012: David A Isenberg
Meryl Streep and the problems of clinical trials.
Arthritis research & therapy 2012;14(2):113.
2011: Panagiotis S Kabouridis; David A Isenberg; Elizabeth C Jury
A negatively charged domain of LAT mediates its interaction with the active form of Lck.
Molecular membrane biology 2011;28(7-8):487-94.
2011: Sanjeev Kumar; Joseph D Maman; Laurence H Pearl; Chelliah T Ravirajan; John A Hinks; David A Isenberg
p185, an immunodominant epitope, is an autoantigen mimotope.
The Journal of biological chemistry 2011;286(29):26220-7.
2011: Shabina M Sultan; Elizabeth Allen; Robert G Cooper; Sangita Agarwal; Patrick Kiely; Chester V Oddis; Jiri Vencovsky; Ingrid E Lundberg; Maryam Dastmalchi; Michael G Hanna; David A Isenberg
Interrater reliability and aspects of validity of the myositis damage index.
Annals of the rheumatic diseases 2011;70(7):1272-6.
2011: Chee-Seng Yee; Vernon T Farewell; David A Isenberg; Bridget Griffiths; Lee-Suan Teh; Ian Bruce; Yasmeen Ahmad; Anisur Rahman; Athiveeraramapandian Prabu; Mohammed Akil; Neil McHugh; Christopher Edwards; David D'Cruz; Munther A Khamashta; Caroline Gordon
The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients.
Rheumatology (Oxford, England) 2011;50(5):982-8.
2011: David A Isenberg; Elizabeth Allen; Vernon T Farewell; David D'Cruz; G S Alarcón; C Aranow; Ian N Bruce; Mary Anne Dooley; P R Fortin; E M Ginzler; D D Gladman; J G Hanly; M Inanc; K Kalunian; Munther A Khamashta; J T Merrill; O Nived; Michelle Petri; R Ramsey-Goldman; G Sturfelt; M Urowitz; D J Wallace; Caroline Gordon; Anisur Rahman
An assessment of disease flare in patients with systemic lupus erythematosus: a comparison of BILAG 2004 and the flare version of SELENA.
Annals of the rheumatic diseases 2011;70(1):54-9.
2010: Chee-Seng Yee; Lynne Cresswell; Vernon T Farewell; Anisur Rahman; Lee-Suan Teh; Bridget Griffiths; Ian Bruce; Yasmeen Ahmad; Athiveeraramapandian Prabu; Mohammed Akil; Neil McHugh; David D'Cruz; Munther A Khamashta; David A Isenberg; Caroline Gordon
Numerical scoring for the BILAG-2004 index.
Rheumatology (Oxford, England) 2010;49(9):1665-9.
2010: Taher E Taher; Kaushal Parikh; Fabian Flores-Borja; Salvinia Mletzko; David A Isenberg; Maikel P Peppelenbosch; Rizgar A Mageed
Protein phosphorylation and kinome profiling reveal altered regulation of multiple signaling pathways in B lymphocytes from patients with systemic lupus erythematosus.
Arthritis and rheumatism 2010;62(8):2412-23.
2010: Anastasia Lambrianides; Christopher J Carroll; Silvia S Pierangeli; Charis Pericleous; Ware Branch; Jurhee Rice; David S Latchman; Paul Townsend; David A Isenberg; Anisur Rahman; Ian Giles
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6622-8.
2010: Simon J Bowman; Yvan St-Pierre; Nurhan Sutcliffe; David A Isenberg; Fiona Goldblatt; Elizabeth Price; John Hamburger; Andrea Richards; Saaeha Rauz; Marian Regan; Shirley Rigby; Adrian Jones; Diarmuid Mulherin; Ann E Clarke
Estimating indirect costs in primary Sjögren's syndrome.
The Journal of rheumatology 2010;37(5):1010-5.
2010: Shabina M Sultan; David A Isenberg
Re-classifying myositis.
Rheumatology (Oxford, England) 2010;49(5):831-3.
2010: Sean G O'Neill; Ian Giles; Anastasia Lambrianides; Jessica Manson; David D'Cruz; Leslie Schrieber; Lyn M March; David S Latchman; David A Isenberg; Anisur Rahman
Antibodies to apolipoprotein A-I, high-density lipoprotein, and C-reactive protein are associated with disease activity in patients with systemic lupus erythematosus.
Arthritis and rheumatism 2010;62(3):845-54.
2010: Elizabeth C Jury; Fabian Flores-Borja; Hardeep S Kalsi; Mark Lazarus; David A Isenberg; Claudia Mauri; Michael R Ehrenstein
Abnormal CTLA-4 function in T cells from patients with systemic lupus erythematosus.
European journal of immunology 2010;40(2):569-78.
2010: Paul A Blair; Lina Yassin Noreña; Fabian Flores-Borja; David J Rawlings; David A Isenberg; Michael R Ehrenstein; Claudia Mauri
CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients.
Immunity 2010;32(1):129-40.
2009: F Goldblatt; Jose Yuste; David A Isenberg; Anisur Rahman; Jeremy Brown
Impaired C3b/iC3b deposition on Streptococcus pneumoniae in serum from patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2009;48(12):1498-501.
2009: Lynne Cresswell; Chee-Seng Yee; Vernon T Farewell; Anisur Rahman; Lee-Suan Teh; Bridget Griffiths; Ian N Bruce; Yasmeen Ahmad; Athiveeraramapandian Prabu; Mohammed Akil; Neil McHugh; Veronica Toescu; David D'Cruz; Munther A Khamashta; Peter Maddison; David A Isenberg; Caroline Gordon
Numerical scoring for the Classic BILAG index.
Rheumatology (Oxford, England) 2009;48(12):1548-52.
2009: Kristine Ng; F Ramos; Shabina M Sultan; David A Isenberg
Concomitant diseases in a cohort of patients with idiopathic myositis during long-term follow-up.
Clinical rheumatology 2009;28(8):947-53.
2009: Eva D Papadimitraki; David A Isenberg
Childhood- and adult-onset lupus: an update of similarities and differences.
Expert review of clinical immunology 2009;5(4):391-403.
2009: F Goldblatt; S Chambers; Anisur Rahman; David A Isenberg
Serious infections in British patients with systemic lupus erythematosus: hospitalisations and mortality.
Lupus 2009;18(8):682-9.
2009: Bryan R Whelan; David A Isenberg
mAbs in nonlupus autoimmune rheumatic disease.
Current opinion in hematology 2009;16(4):280-4.
2009: Chee-Seng Yee; Vernon T Farewell; David A Isenberg; Bridget Griffiths; Lee-Suan Teh; Ian N Bruce; Yasmeen Ahmad; Anisur Rahman; Athiveeraramapandian Prabu; Mohammed Akil; Neil McHugh; Christopher Edwards; David D'Cruz; Munther A Khamashta; Peter Maddison; Caroline Gordon
The BILAG-2004 index is sensitive to change for assessment of SLE disease activity.
Rheumatology (Oxford, England) 2009;48(6):691-5.
2009: Sean G O'Neill; Jose M Pego-Reigosa; Aroon D Hingorani; Rupa Bessant; David A Isenberg; Anisur Rahman
Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2009;48(5):573-5.
2009: Bryan R Whelan; David A Isenberg
Poor response of anti-SRP-positive idiopathic immune myositis to B-cell depletion.
Rheumatology (Oxford, England) 2009;48(5):594-5.
2009: Yiannis Ioannou; Z Romay-Penabad; Charis Pericleous; Ian Giles; E Papalardo; G Vargas; T Shilagard; David S Latchman; David A Isenberg; Anisur Rahman; S Pierangeli
In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept.
Journal of thrombosis and haemostasis : JTH 2009;7(5):833-42.
2009: Tim Y-T Lu; Kristine Ng; Geraldine Cambridge; Maria J Leandro; Jonathan C W Edwards; Michael R Ehrenstein; David A Isenberg
A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: the first fifty patients.
Arthritis and rheumatism 2009;61(4):482-7.
2009: Paul A Blair; Karina A Chavez-Rueda; Jamie G Evans; Mark J Shlomchik; Ayad Eddaoudi; David A Isenberg; Michael R Ehrenstein; Claudia Mauri
Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3492-502.
2009: Jessica J Manson; Alexander Ma; Pauline Rogers; Lesley J Mason; Jo H Berden; Johan Van der Vlag; David P D'Cruz; David A Isenberg; Anisur Rahman
Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study.
Arthritis research & therapy 2009;11(5):R154.
2008: Shabina M Sultan; Elizabeth Allen; Chester V Oddis; Patrick Kiely; Robert G Cooper; Ingrid E Lundberg; Jiri Vencovsky; David A Isenberg
Reliability and validity of the myositis disease activity assessment tool.
Arthritis and rheumatism 2008;58(11):3593-9.
2008: J M Pego-Reigosa; David A Isenberg
Psychosis due to systemic lupus erythematosus: characteristics and long-term outcome of this rare manifestation of the disease.
Rheumatology (Oxford, England) 2008;47(10):1498-502.
2008: Shabina M Sultan; Kristine Ng; J C W Edwards; David A Isenberg; Geraldine Cambridge
Clinical outcome following B cell depletion therapy in eight patients with refractory idiopathic inflammatory myopathy.
Clinical and experimental rheumatology 2008;26(5):887-93.
2008: R C Jeffery; C B Narshi; David A Isenberg
Prevalence, serological features, response to treatment and outcome of critical peripheral ischaemia in a cohort of lupus patients.
Rheumatology (Oxford, England) 2008;47(9):1379-83.
2008: Tim Y-T Lu; Kristine Ng; David A Isenberg
Inflammatory muscle disease assessment.
Current rheumatology reports 2008;10(4):328-32.
2008: R J Barry; Nurhan Sutcliffe; David A Isenberg; E Price; F Goldblatt; M Adler; A Canavan; John Hamburger; A Richards; M Regan; K Gadsby; S Rigby; A Jones; R Mathew; D Mulherin; A Stevenson; P Nightingale; Saaeha Rauz; Simon J Bowman
The Sjögren's Syndrome Damage Index--a damage index for use in clinical trials and observational studies in primary Sjögren's syndrome.
Rheumatology (Oxford, England) 2008;47(8):1193-8.
2008: Chee-Seng Yee; David A Isenberg; Athiveeraramapandian Prabu; Katharina Sokoll; Lee-Suan Teh; Anisur Rahman; Ian N Bruce; Bridget Griffiths; Mohammed Akil; N McHugh; David D'Cruz; Munther A Khamashta; P Maddison; Asad Zoma; Caroline Gordon
BILAG-2004 index captures systemic lupus erythematosus disease activity better than SLEDAI-2000.
Annals of the rheumatic diseases 2008;67(6):873-6.
2008: David A Isenberg
Treating patients with lupus with B-cell depletion.
Lupus 2008;17(5):400-4.
2008: Jeffrey McBride; Francis Guy Gabriel; John Fordham; Torsten Kolind; Gabriela Barcenas-Morales; David A Isenberg; Marlene Swana; Peter J Delves; Jeffrey McBride; Ian Cree; Ivan M Roitt
Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA).
Clinical chemistry 2008;54(5):883-90.
2008: Saowalak Hunnangkul; Dorothea Nitsch; Benjamin Rhodes; Sapna Chadha; Cheri A Roberton; Pedro Pessôa-Lopes; Peter J Norsworthy; Michelle M A Fernando; Peter Charles; Charles Mackworth-Young; David A Isenberg; John C Whittaker; Timothy J Vyse
Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus.
Arthritis and rheumatism 2008;58(4):1116-24.
2008: Ann E Clarke; Pantelis Panopalis; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; Jean-Luc Senécal; Lawrence Joseph; Yvan St-Pierre; T Li
SLE patients with renal damage incur higher health care costs.
Rheumatology (Oxford, England) 2008;47(3):329-33.
2008: Yiannis Ioannou; Anastasia Lambrianides; Geraldine Cambridge; Maria J Leandro; J C W Edwards; David A Isenberg
B cell depletion therapy for patients with systemic lupus erythematosus results in a significant drop in anticardiolipin antibody titres.
Annals of the rheumatic diseases 2008;67(3):425-6.
2008: Anisur Rahman; David A Isenberg
Systemic lupus erythematosus.
The New England journal of medicine 2008;358(9):929-39.
2008: Kristine Ng; David A Isenberg
Sjögren's syndrome: diagnosis and therapeutic challenges in the elderly.
Drugs & aging 2008;25(1):19-33.
2008: F Goldblatt; David A Isenberg
Anti-CD20 monoclonal antibody in rheumatoid arthritis and systemic lupus erythematosus.
Handbook of experimental pharmacology 2008;(181):163-81.
2007: Chee-Seng Yee; Vernon T Farewell; David A Isenberg; Anisur Rahman; Lee-Suan Teh; Bridget Griffiths; Ian N Bruce; Yasmeen Ahmad; Athiveeraramapandian Prabu; Mohammed Akil; Neil McHugh; David D'Cruz; Munther A Khamashta; Peter Maddison; Caroline Gordon
British Isles Lupus Assessment Group 2004 index is valid for assessment of disease activity in systemic lupus erythematosus.
Arthritis and rheumatism 2007;56(12):4113-9.
2007: Simon J Bowman; Nurhan Sutcliffe; David A Isenberg; F Goldblatt; M Adler; E Price; A Canavan; John Hamburger; A Richards; S Rauz; M Regan; Kate Gadsby; S Rigby; A Jones; R Mathew; Diarmuid Mulherin; A Stevenson; P Nightingale
Sjögren's Systemic Clinical Activity Index (SCAI)--a systemic disease activity measure for use in clinical trials in primary Sjögren's syndrome.
Rheumatology (Oxford, England) 2007;46(12):1845-51.
2007: Elizabeth C Jury; Jillian Eldridge; David A Isenberg; Panagiotis S Kabouridis
Agrin signalling contributes to cell activation and is overexpressed in T lymphocytes from lupus patients.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7975-83.
2007: Kristine Ng; Geraldine Cambridge; Maria J Leandro; J C W Edwards; Michael R Ehrenstein; David A Isenberg
B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response.
Annals of the rheumatic diseases 2007;66(9):1259-62.
2007: S A Chambers; Susan Charman; Anisur Rahman; David A Isenberg
Development of additional autoimmune diseases in a multiethnic cohort of patients with systemic lupus erythematosus with reference to damage and mortality.
Annals of the rheumatic diseases 2007;66(9):1173-7.
2007: Anastasia Lambrianides; Ian Giles; Yiannis Ioannou; Lesley J Mason; David S Latchman; Jessica J Manson; David A Isenberg; Anisur Rahman
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome.
Arthritis and rheumatism 2007;56(7):2392-401.
2007: David A Isenberg; Jessica J Manson; Michael R Ehrenstein; Anisur Rahman
Fifty years of anti-ds DNA antibodies: are we approaching journey's end?
Rheumatology (Oxford, England) 2007;46(7):1052-6.
2007: K S Irving; D Sen; H Tahir; Clarissa Pilkington; David A Isenberg
A comparison of autoimmune liver disease in juvenile and adult populations with systemic lupus erythematosus-a retrospective review of cases.
Rheumatology (Oxford, England) 2007;46(7):1171-3.
2007: Pantelis Panopalis; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; Jean-Luc Senécal; John R Penrod; Lawrence Joseph; Yvan St-Pierre; Christian A Pineau; Paul R Fortin; Nurhan Sutcliffe; Jean-Richard Goulet; Denis Choquette; Tamara Grodzicky; John M Esdaile; Ann E Clarke
The systemic lupus erythematosus Tri-Nation study: cumulative indirect costs.
Arthritis and rheumatism 2007;57(1):64-70.
2007: David A Isenberg
BILAG, SLEDAI, SIS, ECLAM, WAM, SLAM .... thank you MAM.
Lupus 2007;16(11):849-51.
2007: Fabian Flores-Borja; Panagiotis S Kabouridis; Elizabeth C Jury; David A Isenberg; Rizgar A Mageed
Altered lipid raft-associated proximal signaling and translocation of CD45 tyrosine phosphatase in B lymphocytes from patients with systemic lupus erythematosus.
Arthritis and rheumatism 2007;56(1):291-302.
2007: Yiannis Ioannou; Charis Pericleous; Ian Giles; David S Latchman; David A Isenberg; Anisur Rahman
Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43.
Arthritis and rheumatism 2007;56(1):280-90.
2007: Frances A Y Borg; David A Isenberg
Syndromes and complications of interferon therapy.
Current opinion in rheumatology 2007;19(1):61-6.
2006: Kristine Ng; Jessica J Manson; Anisur Rahman; David A Isenberg
Association of antinucleosome antibodies with disease flare in serologically active clinically quiescent patients with systemic lupus erythematosus.
Arthritis and rheumatism 2006;55(6):900-4.
2006: Rupa Bessant; Rachel Duncan; Gareth Ambler; Jo Swanton; David A Isenberg; Caroline Gordon; Anisur Rahman
Prevalence of conventional and lupus-specific risk factors for cardiovascular disease in patients with systemic lupus erythematosus: A case-control study.
Arthritis and rheumatism 2006;55(6):892-9.
2006: Elizabeth C Jury; David A Isenberg; Claudia Mauri; Michael R Ehrenstein
Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7416-22.
2006: Geraldine Cambridge; Maria J Leandro; M Teodorescu; J Manson; Anisur Rahman; David A Isenberg; J C W Edwards
B cell depletion therapy in systemic lupus erythematosus: effect on autoantibody and antimicrobial antibody profiles.
Arthritis and rheumatism 2006;54(11):3612-22.
2006: Chee-Seng Yee; Vernon T Farewell; David A Isenberg; Athiveeraramapandian Prabu; Katharina Sokoll; Lee-Suan Teh; Anisur Rahman; Ian N Bruce; Bridget Griffiths; Mohammed Akil; Neil McHugh; David D'Cruz; Munther A Khamashta; Simon Bowman; Peter Maddison; Asad Zoma; Elizabeth Allen; Caroline Gordon
Revised British Isles Lupus Assessment Group 2004 index: a reliable tool for assessment of systemic lupus erythematosus activity.
Arthritis and rheumatism 2006;54(10):3300-5.
2006: M N Lazarus; D Robinson; V Mak; Henrik Møller; David A Isenberg
Incidence of cancer in a cohort of patients with primary Sjogren's syndrome.
Rheumatology (Oxford, England) 2006;45(8):1012-5.
2006: Kristine Ng; Maria J Leandro; J C W Edwards; Michael R Ehrenstein; Geraldine Cambridge; David A Isenberg
Repeated B cell depletion in treatment of refractory systemic lupus erythematosus.
Annals of the rheumatic diseases 2006;65(7):942-5.
2006: Jessica J Manson; David A Isenberg
The origin and pathogenic consequences of anti-dsDNA antibodies in systemic lupus erythematosus.
Expert review of clinical immunology 2006;2(3):377-85.
2006: E Allen; Vernon T Farewell; David A Isenberg; Caroline Gordon
A statistical analysis of the interrelationships between disease activity in different systems in systemic lupus erythematosus.
Rheumatology (Oxford, England) 2006;45(3):308-13.
2006: S G O'Neill; David A Isenberg
Immunizing patients with systemic lupus erythematosus: a review of effectiveness and safety.
Lupus 2006;15(11):778-83.
2006: Yiannis Ioannou; Ian Giles; Anastasia Lambrianides; Chris Richardson; Laurence H Pearl; David S Latchman; David A Isenberg; Anisur Rahman
A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli.
BMC biotechnology 2006;6():8.
2005: Fabian Flores-Borja; Panagiotis S Kabouridis; Elizabeth C Jury; David A Isenberg; Rizgar A Mageed
Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus.
Arthritis and rheumatism 2005;52(12):3955-65.
2005: Maria J Leandro; Geraldine Cambridge; J C W Edwards; Michael R Ehrenstein; David A Isenberg
B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients.
Rheumatology (Oxford, England) 2005;44(12):1542-5.
2005: J Delgado Alves; L J Mason; P R J Ames; P P Chen; Joyce Rauch; Jerrold S Levine; Rebecca Subang; David A Isenberg
Antiphospholipid antibodies are associated with enhanced oxidative stress, decreased plasma nitric oxide and paraoxonase activity in an experimental mouse model.
Rheumatology (Oxford, England) 2005;44(10):1238-44.
2005: Anisur Rahman; S J Bowman; Ian Giles; Y Ioannou; David A Isenberg
Annus mirabilis--a guide to the 6th European Lupus Meeting, 3-5 March 2005.
Rheumatology (Oxford, England) 2005;44(8):962-4.
2005: M N Lazarus; David A Isenberg
Development of additional autoimmune diseases in a population of patients with primary Sjögren's syndrome.
Annals of the rheumatic diseases 2005;64(7):1062-4.
2005: David A Isenberg; Anisur Rahman; E Allen; Vernon T Farewell; Mohammed Akil; Ian N Bruce; David D'Cruz; Bridget Griffiths; Munther A Khamashta; P Maddison; N McHugh; Michael Snaith; Lee-Suan Teh; Chee-Seng Yee; Asad Zoma; Caroline Gordon
BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2005;44(7):902-6.
2005: Pantelis Panopalis; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; JL Senecal; John R Penrod; Lawrence Joseph; Yvan St-Pierre; Christian A Pineau; Paul R Fortin; Nurhan Sutcliffe; Jean-Richard Goulet; Denis Choquette; Tamara Grodzicky; John M Esdaile; Ann E Clarke
The systemic lupus erythematosus tri-nation study: longitudinal changes in physical and mental well-being.
Rheumatology (Oxford, England) 2005;44(6):751-5.
2005: F Goldblatt; David A Isenberg
New therapies for systemic lupus erythematosus.
Clinical and experimental immunology 2005;140(2):205-12.
2005: F Goldblatt; David A Isenberg
New therapies for rheumatoid arthritis.
Clinical and experimental immunology 2005;140(2):195-204.
2005: B J M Ripley; M A Rahman; David A Isenberg; David S Latchman
Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies to Brn-3 and overexpression of Hsp90.
Arthritis and rheumatism 2005;52(4):1171-9.
2005: M M A Fernando; David A Isenberg
How to monitor SLE in routine clinical practice.
Annals of the rheumatic diseases 2005;64(4):524-7.
2005: Sanjeev Kumar; Karen A Bunting; Jatinderpal Kalsi; John A Hinks; David S Latchman; Laurence H Pearl; David A Isenberg
Lupus autoantibodies to native DNA preferentially bind DNA presented on PolIV.
Immunology 2005;114(3):418-27.
2005: Lesley J Mason; Anastasia Lambrianides; Joanna D Haley; Jessica J Manson; David S Latchman; David A Isenberg; Anisur Rahman
Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity.
Arthritis research & therapy 2005;7(5):R971-83.
2005: J Delgado Alves; EL Radway-Bright; S Lee; B Grima; J Hothersall; Chelliah T Ravirajan; David A Isenberg
Antiphospholipid antibodies are induced by in vitro fertilization and correlate with paraoxonase activity and total antioxidant capacity of plasma in infertile women.
Lupus 2005;14(5):373-80.
2005: H Tahir; David A Isenberg
Novel therapies in lupus nephritis.
Lupus 2005;14(1):77-82.
2005: Sanjeev Kumar; Sylvia Nagl; Jatinderpal Kalsi; Chelliah T Ravirajan; Dee Athwal; David S Latchman; Laurence H Pearl; David A Isenberg
Beta-2-glycoprotein specificity of human anti-phospholipid antibody resides on the light chain: a novel mechanism for acquisition of cross-reactivity by an autoantibody.
Molecular immunology 2005;42(1):39-48.
2004: Michael R Ehrenstein; Jamie G Evans; Animesh Singh; Samantha Moore; Gary Warnes; David A Isenberg; Claudia Mauri
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy.
The Journal of experimental medicine 2004;200(3):277-85.
2004: Ann E Clarke; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; Jean-Luc Senécal; John R Penrod; Lawrence Joseph; Yvan St-Pierre; Paul R Fortin; Nurhan Sutcliffe; J Richard Goulet; Denis Choquette; Tamara Grodzicky; John M Esdaile
The systemic lupus erythematosus Tri-nation Study: absence of a link between health resource use and health outcome.
Rheumatology (Oxford, England) 2004;43(8):1016-24.
2004: Thomas Stoll; Nurhan Sutcliffe; J Mach; R Klaghofer; David A Isenberg
Analysis of the relationship between disease activity and damage in patients with systemic lupus erythematosus--a 5-yr prospective study.
Rheumatology (Oxford, England) 2004;43(8):1039-44.
2004: Sanjeev Kumar; Jatinderpal Kalsi; Karen Bunting; Chelliah T Ravirajan; David S Latchman; Laurence H Pearl; David A Isenberg
Fine binding characteristics of human autoantibodies-partial molecular characterization.
Molecular immunology 2004;41(5):495-510.
2004: R Bessant; A Hingorani; L Patel; A MacGregor; David A Isenberg; Anisur Rahman
Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2004;43(7):924-9.
2004: Chee-Seng Yee; Caroline Gordon; C Dostal; P Petera; Jolanta Dadoniene; Bridget Griffiths; B Rozman; David A Isenberg; Gunnar Sturfelt; Ola Nived; J H Turney; Algirdas Venalis; Dwomoa Adu; J S Smolen; Paul Emery
EULAR randomised controlled trial of pulse cyclophosphamide and methylprednisolone versus continuous cyclophosphamide and prednisolone followed by azathioprine and prednisolone in lupus nephritis.
Annals of the rheumatic diseases 2004;63(5):525-9.
2004: Elizabeth C Jury; Panagiotis S Kabouridis; Fabian Flores-Borja; Rizgar A Mageed; David A Isenberg
Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus.
The Journal of clinical investigation 2004;113(8):1176-87.
2004: Chelliah T Ravirajan; Y Wang; L A Matis; L Papadaki; MH Griffiths; David S Latchman; David A Isenberg
Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody.
Rheumatology (Oxford, England) 2004;43(4):442-7.
2004: Lesley J Mason; Chelliah T Ravirajan; Anisur Rahman; Chaim Putterman; David A Isenberg
Is alpha-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis?
Arthritis and rheumatism 2004;50(3):866-70.
2004: Mo Yin Mok; Dominic L Jack; Chak Sing Lau; Daniel Y T Fong; Malcolm W Turner; David A Isenberg; Peter M Lydyard
Antibodies to mannose binding lectin in patients with systemic lupus erythematosus.
Lupus 2004;13(7):522-8.
2004: Joanna D Haley; Lesley J Mason; Sylvia Nagl; Ian Giles; David S Latchman; David A Isenberg; Anisur Rahman
Somatic mutations to arginine residues affect the binding of human monoclonal antibodies to DNA, histones, SmD and Ro antigen.
Molecular immunology 2004;40(11):745-58.
2004: David A Isenberg; E Allen; Vernon T Farewell; Michael R Ehrenstein; Michael G Hanna; Ingrid E Lundberg; Chester V Oddis; Clarissa Pilkington; Paul H Plotz; David Scott; Jiri Vencovsky; R Cooper; Lisa G Rider; F Miller
International consensus outcome measures for patients with idiopathic inflammatory myopathies. Development and initial validation of myositis activity and damage indices in patients with adult onset disease.
Rheumatology (Oxford, England) 2004;43(1):49-54.
2003: Sanjeev Kumar; Sylvia Nagl; Jatinderpal Kalsi; Chelliah T Ravirajan; Dee Athwal; David S Latchman; Laurence H Pearl; David A Isenberg
Anti-cardiolipin/beta-2 glycoprotein activities co-exist on human anti-DNA antibody light chains.
Molecular immunology 2003;40(8):517-30.
2003: Jessica J Manson; David A Isenberg
The pathogenesis of systemic lupus erythematosus.
The Netherlands journal of medicine 2003;61(11):343-6.
2003: Caroline Gordon; Nurhan Sutcliffe; Jan Skan; Thomas Stoll; David A Isenberg
Definition and treatment of lupus flares measured by the BILAG index.
Rheumatology (Oxford, England) 2003;42(11):1372-9.
2003: Ian Giles; Joanna D Haley; Sylvia Nagl; David S Latchman; Pojen P Chen; Reginald U Chukwuocha; David A Isenberg; Anisur Rahman
Relative importance of different human aPL derived heavy and light chains in the binding of aPL to cardiolipin.
Molecular immunology 2003;40(1):49-60.
2003: Ian Giles; David A Isenberg; David S Latchman; Anisur Rahman
How do antiphospholipid antibodies bind beta2-glycoprotein I?
Arthritis and rheumatism 2003;48(8):2111-21.
2003: J Delgado Alves; Sanjeev Kumar; David A Isenberg
Cross-reactivity between anti-cardiolipin, anti-high-density lipoprotein and anti-apolipoprotein A-I IgG antibodies in patients with systemic lupus erythematosus and primary antiphospholipid syndrome.
Rheumatology (Oxford, England) 2003;42(7):893-9.
2003: Jessica J Manson; David A Isenberg
Antiphospholipid syndrome.
The international journal of biochemistry & cell biology 2003;35(7):1015-20.
2003: Elizabeth C Jury; Panagiotis S Kabouridis; Amina Abba; Rizgar A Mageed; David A Isenberg
Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus.
Arthritis and rheumatism 2003;48(5):1343-54.
2003: Ian Giles; Joanna D Haley; Sylvia Nagl; David A Isenberg; David S Latchman; Anisur Rahman
A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs.
Seminars in arthritis and rheumatism 2003;32(4):246-65.
2003: Shabina M Sultan; S Begum; David A Isenberg
Prevalence, patterns of disease and outcome in patients with systemic lupus erythematosus who develop severe haematological problems.
Rheumatology (Oxford, England) 2003;42(2):230-4.
2003: D Sen; David A Isenberg
Antineutrophil cytoplasmic autoantibodies in systemic lupus erythematosus.
Lupus 2003;12(9):651-8.
2003: F B Karassa; M Magliano; David A Isenberg
Suicide attempts in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 2003;62(1):58-60.
2002: J Delgado Alves; P R J Ames; S Donohue; Lee Stanyer; Jaffar Nourooz-Zadeh; Chelliah T Ravirajan; David A Isenberg; J Noorouz-Zadeh
Antibodies to high-density lipoprotein and beta2-glycoprotein I are inversely correlated with paraoxonase activity in systemic lupus erythematosus and primary antiphospholipid syndrome.
Arthritis and rheumatism 2002;46(10):2686-94.
2002: Maria J Leandro; J C W Edwards; Geraldine Cambridge; Michael R Ehrenstein; David A Isenberg
An open study of B lymphocyte depletion in systemic lupus erythematosus.
Arthritis and rheumatism 2002;46(10):2673-7.
2002: M Magliano; David A Isenberg; J Hillson
Pulmonary hypertension in autoimmune rheumatic diseases: where are we now?
Arthritis and rheumatism 2002;46(8):1997-2009.
2002: S Begum; C Li; Lucy R Wedderburn; V Blackwell; David A Isenberg
Concurrence of sarcoidosis and systemic lupus erythematosus in three patients.
Clinical and experimental rheumatology 2002;20(4):549-52.
2002: I Haq; David A Isenberg
Myositis and swollen knees: disease or treatment complication?
Annals of the rheumatic diseases 2002;61(6):544-6.
2002: K E Moss; Y Ioannou; Shabina M Sultan; I Haq; David A Isenberg
Outcome of a cohort of 300 patients with systemic lupus erythematosus attending a dedicated clinic for over two decades.
Annals of the rheumatic diseases 2002;61(5):409-13.
2002: Athanasios G Tzioufas; R Wassmuth; Urania Dafni; Apostolia Guialis; Hans-Jacob Haga; David A Isenberg; Roland Jonsson; J R Kalden; H Kiener; Constantinos Sakarellos; J S Smolen; Nurhan Sutcliffe; C Vitali; EE Yiannaki; Haralampos M Moutsopoulos
Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): a European multicentre study.
Annals of the rheumatic diseases 2002;61(5):398-404.
2002: Rizgar A Mageed; David A Isenberg
Tumour necrosis factor alpha in systemic lupus erythematosus and anti-DNA autoantibody production.
Lupus 2002;11(12):850-5.
2002: Chelliah T Ravirajan; David A Isenberg
Transgenic models of tolerance and autoimmunity: with special reference to systemic lupus erythematosus.
Lupus 2002;11(12):843-9.
2002: S Kumar; Jatinderpal Kalsi; Chelliah T Ravirajan; David S Latchman; Laurence H Pearl; David A Isenberg
Molecular expression systems for anti-DNA antibodies--2.
Lupus 2002;11(12):833-42.
2002: GS Dean; A Anand; A Blofeld; David A Isenberg; Peter M Lydyard
Characterization of CD3+ CD4- CD8- (double negative) T cells in patients with systemic lupus erythematosus: production of IL-4.
Lupus 2002;11(8):501-7.
2002: A Anand; GS Dean; K Quereshi; David A Isenberg; Peter M Lydyard
Characterization of CD3+ CD4- CD8- (double negative) T cells in patients with systemic lupus erythematosus: activation markers.
Lupus 2002;11(8):493-500.
2002: NA Dayal; David A Isenberg
SLE/myositis overlap: are the manifestations of SLE different in overlap disease?
Lupus 2002;11(5):293-8.
2002: NA Dayal; Caroline Gordon; L Tucker; David A Isenberg
The SLICC damage index: past, present and future.
Lupus 2002;11(4):261-5.
2002: Shabina M Sultan; Y Ioannou; K Moss; David A Isenberg
Outcome in patients with idiopathic inflammatory myositis: morbidity and mortality.
Rheumatology (Oxford, England) 2002;41(1):22-6.
2002: D Pyne; David A Isenberg
Autoimmune thyroid disease in systemic lupus erythematosus.
Annals of the rheumatic diseases 2002;61(1):70-2.
2001: Chelliah T Ravirajan; L Rowse; J R MacGowan; David A Isenberg
An analysis of clinical disease activity and nephritis-associated serum autoantibody profiles in patients with systemic lupus erythematosus: a cross-sectional study.
Rheumatology (Oxford, England) 2001;40(12):1405-12.
2001: Frederick W Miller; Lisa G Rider; Y L Chung; R Cooper; K Danko; Vernon T Farewell; I Lundberg; C Morrison; L Oakley; I Oakley; Clarissa Pilkington; Jiri Vencovsky; K Vincent; David Scott; David A Isenberg
Proposed preliminary core set measures for disease outcome assessment in adult and juvenile idiopathic inflammatory myopathies.
Rheumatology (Oxford, England) 2001;40(11):1262-73.
2001: JE Joseph; Paul Harrison; Ian J Mackie; David A Isenberg; Samuel J Machin
Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis.
British journal of haematology 2001;115(2):451-9.
2001: NA Dayal; David A Isenberg
Assessment of inflammatory myositis.
Current opinion in rheumatology 2001;13(6):488-92.
2001: Lesley J Mason; Chelliah T Ravirajan; David S Latchman; David A Isenberg
A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of 'leaky' SCID mice.
Clinical and experimental immunology 2001;126(1):137-42.
2001: K E Moss; David A Isenberg
Comparison of renal disease severity and outcome in patients with primary antiphospholipid syndrome, antiphospholipid syndrome secondary to systemic lupus erythematosus (SLE) and SLE alone.
Rheumatology (Oxford, England) 2001;40(8):863-7.
2001: A Sharma; David A Isenberg; Betty Diamond
Crossreactivity of human anti-dsDNA antibodies to phosphorylcholine: clues to their origin.
Journal of autoimmunity 2001;16(4):479-84.
2001: Sanjeev Kumar; Jatinderpal Kalsi; David S Latchman; Laurence H Pearl; David A Isenberg
Expression of the Fabs of human auto-antibodies in Escherichia coli: optimization and determination of their fine binding characteristics and cross-reactivity.
Journal of molecular biology 2001;308(3):527-39.
2001: GS Dean; David A Isenberg
Detection of anticardiolipin antibodies in culture supernatants.
Clinical and experimental rheumatology 2001;19(3):251-7.
2001: J Tyrrell-Price; Peter M Lydyard; David A Isenberg
The effect of interleukin-10 and of interleukin-12 on the in vitro production of anti-double-stranded DNA antibodies from patients with systemic lupus erythematosus.
Clinical and experimental immunology 2001;124(1):118-25.
2001: Anisur Rahman; Joanna D Haley; EL Radway-Bright; Sylvia Nagl; D G Low; David S Latchman; David A Isenberg
The importance of somatic mutations in the V(lambda) gene 2a2 in human monoclonal anti-DNA antibodies.
Journal of molecular biology 2001;307(1):149-60.
2001: F B Karassa; David A Isenberg
Spontaneous rupture of the spleen: an unusual complication of systemic lupus erythematosus.
Lupus 2001;10(12):876-8.
2001: David A Isenberg; D Gladman
The Systemic Lupus International Collaborating Clinics Group--origins and outcomes.
Lupus 2001;10(5):375-7.
2001: Nurhan Sutcliffe; Ann E Clarke; R Taylor; C Frost; David A Isenberg
Total costs and predictors of costs in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2001;40(1):37-47.
2001: R Mediwake; David A Isenberg; G A Schellekens; W J van Venrooij
Use of anti-citrullinated peptide and anti-RA33 antibodies in distinguishing erosive arthritis in patients with systemic lupus erythematosus and rheumatoid arthritis.
Annals of the rheumatic diseases 2001;60(1):67-8.
2000: Sanjeev Kumar; Jatinderpal Kalsi; Chelliah T Ravirajan; Anisur Rahman; Dee Athwal; David S Latchman; David A Isenberg; Laurence H Pearl
Molecular cloning and expression of the Fabs of human autoantibodies in Escherichia coli. Determination of the heavy or light chain contribution to the anti-DNA/-cardiolipin activity of the Fab.
The Journal of biological chemistry 2000;275(45):35129-36.
2000: Ann E Clarke; John R Penrod; Yvan St-Pierre; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; JL Senecal; Paul R Fortin; Nurhan Sutcliffe; Jean-Richard Goulet; Denis Choquette; Tamara Grodzicky; John M Esdaile
Underestimating the value of women: assessing the indirect costs of women with systemic lupus erythematosus. Tri-Nation Study Group.
The Journal of rheumatology 2000;27(11):2597-604.
2000: Shabina M Sultan; Y Ioannou; David A Isenberg
Is there an association of malignancy with systemic lupus erythematosus? An analysis of 276 patients under long-term review.
Rheumatology (Oxford, England) 2000;39(10):1147-52.
2000: Thomas Stoll; Nurhan Sutcliffe; R Klaghofer; David A Isenberg
Do present damage and health perception in patients with systemic lupus erythematosus predict extent of future damage?: a prospective study.
Annals of the rheumatic diseases 2000;59(10):832-5.
2000: Yiannis Ioannou; David A Isenberg
Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy.
Arthritis and rheumatism 2000;43(7):1431-42.
2000: Andrew D Moore; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; Jean-Luc Senécal; Yvan St-Pierre; Lawrence Joseph; John R Penrod; Paul R Fortin; Nurhan Sutcliffe; Jean-Richard Goulet; Denis Choquette; Tamara Grodzicky; John M Esdaile; Ann E Clarke
The use of alternative medical therapies in patients with systemic lupus erythematosus. Trination Study Group.
Arthritis and rheumatism 2000;43(6):1410-8.
2000: David A Isenberg; Mike Salmon
How to supervise a thesis--best practice. Research and Training Committee of the British Society for Rheumatology.
Rheumatology (Oxford, England) 2000;39(5):560-2.
2000: EL Radway-Bright; Chelliah T Ravirajan; David A Isenberg
The prevalence of antibodies to anionic phospholipids in patients with the primary antiphospholipid syndrome, systemic lupus erythematosus and their relatives and spouses.
Rheumatology (Oxford, England) 2000;39(4):427-31.
2000: GS Dean; J Tyrrell-Price; E Crawley; David A Isenberg
Cytokines and systemic lupus erythematosus.
Annals of the rheumatic diseases 2000;59(4):243-51.
2000: V Pittoni; Chelliah T Ravirajan; S Donohoe; Samuel J Machin; Peter M Lydyard; David A Isenberg
Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and beta2-glycoprotein I (beta2-GPI) on apoptotic cells.
Clinical and experimental immunology 2000;119(3):533-43.
2000: Nurhan Sutcliffe; C Smith; Paul M Speight; David A Isenberg
Mucosa-associated lymphoid tissue lymphomas in two patients with rheumatoid arthritis on second-line agents, and secondary Sjögren's syndrome.
Rheumatology (Oxford, England) 2000;39(2):185-8.
2000: David A Isenberg; Caroline Gordon
From BILAG to BLIPS--disease activity assessment in lupus past, present and future.
Lupus 2000;9(9):651-4.
2000: C M Tench; David A Isenberg
The variation in anti-ENA characteristics between different ethnic populations with systemic lupus erythematosus over a 10-year period.
Lupus 2000;9(5):374-6.
2000: David A Isenberg; J S Smolen
European perspective of clinical trials in systemic lupus erythematosus.
Lupus 2000;9(4):233-5.
1999: Nurhan Sutcliffe; Ann E Clarke; Caroline Gordon; Vernon T Farewell; David A Isenberg
The association of socio-economic status, race, psychosocial factors and outcome in patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 1999;38(11):1130-7.
1999: Nurhan Sutcliffe; Ann E Clarke; Carey Levinton; C Frost; Caroline Gordon; David A Isenberg
Associates of health status in patients with systemic lupus erythematosus.
The Journal of rheumatology 1999;26(11):2352-6.
1999: Y Ioannou; S Sultan; David A Isenberg
Myositis overlap syndromes.
Current opinion in rheumatology 1999;11(6):468-74.
1999: Shabina M Sultan; Y Ioannou; David A Isenberg
A review of gastrointestinal manifestations of systemic lupus erythematosus.
Rheumatology (Oxford, England) 1999;38(10):917-32.
1999: E Crawley; Patricia Woo; David A Isenberg
Single nucleotide polymorphic haplotypes of the interleukin-10 5' flanking region are not associated with renal disease or serology in Caucasian patients with systemic lupus erythematosus.
Arthritis and rheumatism 1999;42(9):2017-8.
1999: Michael Voulgarelis; Urania Dafni; David A Isenberg; Haralampos M Moutsopoulos
Malignant lymphoma in primary Sjögren's syndrome: a multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome.
Arthritis and rheumatism 1999;42(8):1765-72.
1999: EL Radway-Bright; M Inanc; David A Isenberg
Animal models of the antiphospholipid syndrome.
Rheumatology (Oxford, England) 1999;38(7):591-601.
1999: Ann E Clarke; Michelle Petri; Susan Manzi; David A Isenberg; Caroline Gordon; JL Senecal; Yvan St-Pierre; Lawrence Joseph; John R Penrod; Paul R Fortin; Nurhan Sutcliffe; Jean-Richard Goulet; Denis Choquette; Tamara Grodzicky; DS Danoff; Vivian Ho; John M Esdaile
An international perspective on the well being and health care costs for patients with systemic lupus erythematosus. Tri-Nation Study Group.
The Journal of rheumatology 1999;26(7):1500-11.
1999: B J Ripley; Anastasis Stephanou; David A Isenberg; David S Latchman
Interleukin-10 activates heat-shock protein 90beta gene expression.
Immunology 1999;97(2):226-31.
1999: Lesley J Mason; L M Timothy; David A Isenberg; Jatinderpal Kalsi
Immunization with a peptide of Sm B/B' results in limited epitope spreading but not autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5099-105.
1999: S Menon; E Jameson-Shortall; SP Newman; M R Hall-Craggs; RJ Chinn; David A Isenberg
A longitudinal study of anticardiolipin antibody levels and cognitive functioning in systemic lupus erythematosus.
Arthritis and rheumatism 1999;42(4):735-41.
1999: Jatinderpal Kalsi; Chelliah T Ravirajan; A Rahman; David A Isenberg
Structure-function analysis and the molecular origins of anti-DNA antibodies in systemic lupus erythematosus.
Expert reviews in molecular medicine 1999;1999():1-28.
1999: S Hussain; David A Isenberg
Autoimmune rheumatic diseases and the heart.
Hospital medicine (London, England : 1998) 1999;60(2):95-9.
1999: Anastasis Stephanou; David A Isenberg; K Nakajima; David S Latchman
Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters.
The Journal of biological chemistry 1999;274(3):1723-8.
1999: Chelliah T Ravirajan; V Pittoni; David A Isenberg
Apoptosis in human autoimmune diseases.
International reviews of immunology 1999;18(5-6):563-89.
1999: Y Ioannou; David A Isenberg
Immunisation of patients with systemic lupus erythematosus: the current state of play.
Lupus 1999;8(7):497-501.
1998: M A Rahman; C A Kettleborough; David S Latchman; David A Isenberg
Properties of whole human IgG molecules produced by the expression of cloned anti-DNA antibody cDNA in mammalian cells.
Journal of autoimmunity 1998;11(6):661-9.
1998: A Stephanou; David S Latchman; David A Isenberg
The regulation of heat shock proteins and their role in systemic lupus erythematosus.
Seminars in arthritis and rheumatism 1998;28(3):155-62.
1998: Anisur Rahman; David S Latchman; David A Isenberg
Immunoglobulin variable region sequences of human monoclonal anti-DNA antibodies.
Seminars in arthritis and rheumatism 1998;28(3):141-54.
1998: M Inanç; S Donohoe; Chelliah T Ravirajan; EL Radway-Bright; Ian Mackie; Samuel Machin; David A Isenberg
Anti-beta2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome.
British journal of rheumatology 1998;37(10):1089-94.
1998: Anisur Rahman; David S Latchman; David A Isenberg
The role of in vitro expression systems in the investigation of antibodies to DNA.
Seminars in arthritis and rheumatism 1998;28(2):130-9.
1998: A J Hakim; Samuel J Machin; David A Isenberg
Autoimmune thrombocytopenia in primary antiphospholipid syndrome and systemic lupus erythematosus: the response to splenectomy.
Seminars in arthritis and rheumatism 1998;28(1):20-5.
1998: Anastasis Stephanou; S Conroy; David A Isenberg; Domenico Maione; V Poli; G Ciliberto; David S Latchman
Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies.
Journal of autoimmunity 1998;11(3):249-53.
1998: M Richter Cohen; G Steiner; J S Smolen; David A Isenberg
Erosive arthritis in systemic lupus erythematosus: analysis of a distinct clinical and serological subset.
British journal of rheumatology 1998;37(4):421-4.
1998: Anastasis Stephanou; David A Isenberg; S Akira; T Kishimoto; David S Latchman
The nuclear factor interleukin-6 (NF-IL6) and signal transducer and activator of transcription-3 (STAT-3) signalling pathways co-operate to mediate the activation of the hsp90beta gene by interleukin-6 but have opposite effects on its inducibility by heat shock.
The Biochemical journal 1998;330 ( Pt 1)():189-95.
1998: W M Williams; David A Isenberg
Naturally occurring anti-idiotypic antibodies reactive with anti-DNA antibodies in systemic lupus erythematosus.
Lupus 1998;7(3):164-75.
1998: Chelliah T Ravirajan; M A Rahman; L Papadaki; MH Griffiths; Jatinderpal Kalsi; A C Martin; Michael R Ehrenstein; David S Latchman; David A Isenberg
Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis.
European journal of immunology 1998;28(1):339-50.
1998: Nurhan Sutcliffe; Thomas Stoll; S Pyke; David A Isenberg
Functional disability and end organ damage in patients with systemic lupus erythematosus (SLE), SLE and Sjögren's syndrome (SS), and primary SS.
The Journal of rheumatology 1998;25(1):63-8.
1997: M Inanç; EL Radway-Bright; David A Isenberg
beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now?
British journal of rheumatology 1997;36(12):1247-57.
1997: D Fishman; David A Isenberg
Splenic involvement in rheumatic diseases.
Seminars in arthritis and rheumatism 1997;27(3):141-55.
1997: M J Garton; David A Isenberg
Clinical features of lupus myositis versus idiopathic myositis: a review of 30 cases.
British journal of rheumatology 1997;36(10):1067-74.
1997: Thomas Stoll; Caroline Gordon; B Seifert; K Richardson; J Malik; P A Bacon; David A Isenberg
Consistency and validity of patient administered assessment of quality of life by the MOS SF-36; its association with disease activity and damage in patients with systemic lupus erythematosus.
The Journal of rheumatology 1997;24(8):1608-14.
1997: RA Fox; David A Isenberg
Human immunodeficiency virus infection in systemic lupus erythematosus.
Arthritis and rheumatism 1997;40(6):1168-72.
1997: N Sutcliffe; V Morris; B Gomperts; D J Brazier; David A Isenberg; G Cambridge
Relationship between the development of blindness in Churg-Strauss syndrome and anti-myeloperoxidase antibodies.
British journal of rheumatology 1997;36(2):273-5.
1997: David A Isenberg; M Garton; M W Reichlin; M Reichlin
Long-term follow-up of autoantibody profiles in black female lupus patients and clinical comparison with Caucasian and Asian patients.
British journal of rheumatology 1997;36(2):229-33.
1997: L M Rose; D S Latchman; David A Isenberg
Apoptosis in peripheral lymphocytes in systemic lupus erythematosus: a review.
British journal of rheumatology 1997;36(2):158-63.
1997: S Menon; M A Rahman; C T Ravirajan; D Kandiah; C M Longhurst; T McNally; W M Williams; David S Latchman; David A Isenberg
The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies.
Journal of autoimmunity 1997;10(1):43-57.
1997: Thomas Stoll; Gerold Stucki; J Malik; S Pyke; David A Isenberg
Association of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index with measures of disease activity and health status in patients with systemic lupus erythematosus.
The Journal of rheumatology 1997;24(2):309-13.
1997: L M Rose; David S Latchman; David A Isenberg
Elevated soluble fas production in SLE correlates with HLA status not with disease activity.
Lupus 1997;6(9):717-22.
1997: F M Erkeller-Yuksel; Peter M Lydyard; David A Isenberg
Lack of NK cells in lupus patients with renal involvement.
Lupus 1997;6(9):708-12.
1997: H Winska-Wiloch; S Muller; D R Katz; Leonora Wilkinson; P R Hutchings; David A Isenberg
Immunogenic properties of synthetic fragments of Sm-D protein in normal and lupus mice.
Lupus 1997;6(8):656-67.
1997: J E McDonagh; Munther A Khamashta; S Menon; Anisur Rahman; David A Isenberg
A young woman with SLE: diagnostic and therapeutic challenges.
Lupus 1997;6(8):633-7.
1997: David A Isenberg; Chelliah T Ravirajan; Anisur Rahman; Jatinderpal Kalsi
The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996.
Lupus 1997;6(3):290-304.
1997: E C Rankin; David A Isenberg
IgA deficiency and SLE: prevalence in a clinic population and a review of the literature.
Lupus 1997;6(4):390-4.
1997: Thomas Stoll; G Stucki; C Gordon; David A Isenberg
A damage index for lupus patients--where are we now?
Lupus 1997;6(3):219-22.
1997: RJ Chinn; Iain D Wilkinson; Margaret A Hall-Craggs; Martyn Nigel James Paley; E Shortall; S Carter; BE Kendall; David A Isenberg; SP Newman; MJ Harrison
Magnetic resonance imaging of the brain and cerebral proton spectroscopy in patients with systemic lupus erythematosus.
Arthritis and rheumatism 1997;40(1):36-46.
1997: Anastasis Stephanou; V Amin; David A Isenberg; S Akira; T Kishimoto; David S Latchman
Interleukin 6 activates heat-shock protein 90 beta gene expression.
The Biochemical journal 1997;321 ( Pt 1)():103-6.
1996: W M Williams; David A Isenberg
A cross-sectional study of anti-DNA antibodies in the serum and IgG and IgM fraction of healthy individuals, patients with systemic lupus erythematosus and their relatives.
Lupus 1996;5(6):576-86.
1996: Pierre Youinou; David A Isenberg; Jatinderpal Kalsi; J M Dugoujon; Chelliah T Ravirajan; S Muller; F Blanco; J C Piette; L Guillevin; J Jouquan; G Semana; D Salmon; Y Shoenfeld; J F Bach
Interplay of four idiotypes and interaction with autoantibodies in lupus patients, their relatives and their spouses.
Journal of autoimmunity 1996;9(6):767-75.
1996: Marianna M Newkirk; J B Shiroky; N Johnson; DS Danoff; David A Isenberg; C Shustik; G R Pearson
Rheumatic disease patients, prone to Sjögren's syndrome and/or lymphoma, mount an antibody response to BHRF1, the Epstein-Barr viral homologue of BCL-2.
British journal of rheumatology 1996;35(11):1075-81.
1996: Thomas Stoll; Gerold Stucki; J Malik; S Pyke; David A Isenberg
Further validation of the BILAG disease activity index in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 1996;55(10):756-60.
1996: A Rahman; S Menon; D S Latchman; David A Isenberg
Sequences of monoclonal antiphospholipid antibodies: variations on an anti-DNA antibody theme.
Seminars in arthritis and rheumatism 1996;26(2):515-25.
1996: M R Cohen; David A Isenberg
Ultraviolet irradiation in systemic lupus erythematosus: friend or foe?
British journal of rheumatology 1996;35(10):1002-7.
1996: T McNally; Ian J Mackie; David A Isenberg; S J Machin
beta 2 glycoprotein-I inhibits factor XII activation on triglyceride rich lipoproteins: the effect of antibodies from plasma of patients with antiphospholipid syndrome.
Thrombosis and haemostasis 1996;76(2):220-5.
1996: Chelliah T Ravirajan; Catherine Sarraf; T V Anilkumar; M C Golding; Stuart McDonald; David A Isenberg
An analysis of apoptosis in lymphoid organs and lupus disease in murine systemic lupus erythematosus (SLE).
Clinical and experimental immunology 1996;105(2):306-12.
1996: P A Jeddi; K B Bodman-Smith; Torben Lund; Peter M Lydyard; L Mengle-Gaw; David A Isenberg; P Youinou; Peter J Delves
Agalactosyl IgG and beta-1,4-galactosyltransferase gene expression in rheumatoid arthritis patients and in the arthritis-prone MRL lpr/lpr mouse.
Immunology 1996;87(4):654-9.
1996: Jatinderpal Kalsi; A C Martin; Y Hirabayashi; M Ehrenstein; C M Longhurst; Chelliah T Ravirajan; Marketa Zvelebil; B D Stollar; Janet M Thornton; David A Isenberg
Functional and modelling studies of the binding of human monoclonal anti-DNA antibodies to DNA.
Molecular immunology 1996;33(4-5):471-83.
1996: Thomas Stoll; B Seifert; David A Isenberg
SLICC/ACR Damage Index is valid, and renal and pulmonary organ scores are predictors of severe outcome in patients with systemic lupus erythematosus.
British journal of rheumatology 1996;35(3):248-54.
1996: C Longhurst; M R Ehrenstein; B Leaker; F K Stevenson; MB Spellerberg; C Chapman; D Latchmen; David A Isenberg; Geraldine Cambridge
Analysis of immunoglobulin variable region genes of a human IgM anti-myeloperoxidase antibody derived from a patient with vasculitis.
Immunology 1996;87(2):334-8.
1996: S E Conroy; L Tucker; David S Latchman; David A Isenberg
Incidence of anti Hsp 90 and 70 antibodies in children with SLE, juvenile dermatomyositis and juvenile chronic arthritis.
Clinical and experimental rheumatology 1996;14(1):99-104.
1995: W M Williams; N A Staines; S Muller; David A Isenberg
Human T cell responses to autoantibody variable region peptides.
Lupus 1995;4(6):464-71.
1995: T McNally; Ian J Mackie; S J Machin; David A Isenberg
Increased levels of beta 2 glycoprotein-I antigen and beta 2 glycoprotein-I binding antibodies are associated with a history of thromboembolic complications in patients with SLE and primary antiphospholipid syndrome.
British journal of rheumatology 1995;34(11):1031-6.
1995: S Menon; David A Isenberg
Fetal calf serum in growth medium obscures the detection of early anticardiolipin antibody secreting clones.
Journal of immunological methods 1995;186(1):65-70.
1995: T McNally; Gordon Purdy; Ian J Mackie; S J Machin; David A Isenberg
The use of an anti-beta 2-glycoprotein-I assay for discrimination between anticardiolipin antibodies associated with infection and increased risk of thrombosis.
British journal of haematology 1995;91(2):471-3.
1995: S Menon; David A Isenberg
Rheumatological manifestations of haematological diseases.
Annals of the rheumatic diseases 1995;54(10):787-95.
1995: David A Isenberg
Humoral immunity and glycosylation abnormalities in rheumatoid arthritis.
Clinical and experimental rheumatology 1995;13 Suppl 12():S17-20.
1995: M R Ehrenstein; D R Katz; M H Griffiths; L Papadaki; T H Winkler; J R Kalden; David A Isenberg
Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice.
Kidney international 1995;48(3):705-11.
1995: Jatinderpal Kalsi; A C Martin; David A Isenberg
Structure--function relationships of anti-DNA antibodies.
Lupus 1995;4(4):245-8.
1995: Chelliah T Ravirajan; I Harmer; T McNally; A Hohmann; C G Mackworth-Young; David A Isenberg
Phospholipid binding specificities and idiotype expression of hybridoma derived monoclonal autoantibodies from splenic cells of patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 1995;54(6):471-6.
1995: J Keusch; Peter M Lydyard; David A Isenberg; Peter J Delves
beta 1,4-Galactosyltransferase activity in B cells detected using a simple ELISA-based assay.
Glycobiology 1995;5(4):365-700.
1995: D Kausman; David A Isenberg
Thyroid autoimmunity in systemic lupus erythematosus: the clinical significance of a fluctuating course.
British journal of rheumatology 1995;34(4):361-4.
1995: E C Rankin; E H Choy; D Kassimos; Gabrielle Kingsley; A M Sopwith; David A Isenberg; Gabriel S Panayi
The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis.
British journal of rheumatology 1995;34(4):334-42.
1995: L M Rose; David S Latchman; David A Isenberg
Bcl-2 expression is unaltered in unfractionated peripheral blood mononuclear cells in patients with systemic lupus erythematosus.
British journal of rheumatology 1995;34(4):316-20.
1995: M R Ehrenstein; S E Conroy; J Heath; D S Latchman; David A Isenberg
The occurrence, nature and distribution of flares in a cohort of patients with systemic lupus erythematosus: a rheumatological view.
British journal of rheumatology 1995;34(3):257-60.
1995: Chelliah T Ravirajan; Pierre Youinou; P Le Goff; Richard Watts; David A Isenberg
Expression of a human fetal anti-DNA antibody idiotype BEG-2 beta in the families of patients with rheumatoid arthritis.
Autoimmunity 1995;21(4):269-75.
1995: Chelliah T Ravirajan; S Muller; D R Katz; David A Isenberg
Effect of histone and histone-RNA complexes on the disease process of murine systemic lupus erythematosus.
Autoimmunity 1995;21(2):117-22.
1994: D Kausman; David A Isenberg
Role of the biologics in autoimmunity.
Lupus 1994;3(6):461-6.
1994: David A Isenberg
Secondary Sjögren's syndrome--the sausage factory revisited.
Clinical and experimental rheumatology 1994;12 Suppl 11():S19-21.
1994: T McNally; S E Cotterell; Ian J Mackie; David A Isenberg; S J Machin
The interaction of beta 2 glycoprotein-I and heparin and its effect on beta 2 glycoprotein-I antiphospholipid antibody cofactor function in plasma.
Thrombosis and haemostasis 1994;72(4):578-81.
1994: S Menon; J M Round; David A Isenberg
Rhabdomyolysis in a patient with discoid lupus erythematosus.
The Journal of rheumatology 1994;21(10):1967-9.
1994: T McNally; M Crook; Ian J Mackie; David A Isenberg; S J Machin
Beta 2 glycoprotein-I antigen is increased in primary hyperlipidaemia.
British journal of haematology 1994;88(2):424-6.
1994: M A Rahman; David A Isenberg
Autoantibodies in systemic lupus erythematosus.
Current opinion in rheumatology 1994;6(5):468-73.
1994: David A Isenberg; G Steiner; J S Smolen
Clinical utility and serological connections of anti-RA33 antibodies in systemic lupus erythematosus.
The Journal of rheumatology 1994;21(7):1260-3.
1994: M R Ehrenstein; B Hartley; L S Wilkinson; David A Isenberg
Comparison of a monoclonal and polyclonal anti-idiotype against a human IgG anti-DNA antibody.
Journal of autoimmunity 1994;7(3):349-67.
1994: V B Dhillon; S McCallum; David S Latchman; David A Isenberg
Elevation of the 90 kDa heat-shock protein in specific subsets of systemic lupus erythematosus.
The Quarterly journal of medicine 1994;87(4):215-22.
1994: M R Ehrenstein; C M Longhurst; David S Latchman; David A Isenberg
Serological and genetic characterization of a human monoclonal immunoglobulin G anti-DNA idiotype.
The Journal of clinical investigation 1994;93(4):1787-97.
1994: G B Faulds; David A Isenberg; D S Latchman
The tissue specific elevation in synthesis of the 90 kDa heat shock protein precedes the onset of disease in lupus prone MRL/lpr mice.
The Journal of rheumatology 1994;21(2):234-8.
1994: F Blanco; C Longhurst; R Watts; Jatinderpal Kalsi; H W Wiloch; Pierre Youinou; David S Latchman; David A Isenberg
Identification and characterization of a new human DNA reactive monoclonal antibody and a common idiotype, WRI 176 Id beta.
Lupus 1994;3(1):15-24.
1994: David A Isenberg; M R Ehrenstein; C Longhurst; Jatinderpal Kalsi
The origin, sequence, structure, and consequences of developing anti-DNA antibodies. A human perspective.
Arthritis and rheumatism 1994;37(2):169-80.
1994: E C Rankin; G H Nield; David A Isenberg
Deterioration of renal function in a patient with lupus.
Annals of the rheumatic diseases 1994;53(1):67-71.
1994: J D Huntriss; B M Twomey; David A Isenberg; David S Latchman
Enhanced transcription of the gene encoding the SmN autoantigen in patients with systemic lupus erythematosus does not result in enhanced levels of the SmN protein.
Autoimmunity 1994;19(2):81-7.
1994: David S Latchman; David A Isenberg
The role of hsp90 in SLE.
Autoimmunity 1994;19(3):211-8.
1994: L M Rose; David S Latchman; David A Isenberg
Bcl-2 and Fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus?
Autoimmunity 1994;17(4):271-8.
1993: T McNally; Ian J Mackie; David A Isenberg; S J Machin
Immunoelectrophoresis and ELISA techniques for assay of plasma beta 2 glycoprotein-1 and the influence of plasma lipids.
Thrombosis research 1993;72(4):275-86.
1993: J C W Edwards; L S Wilkinson; Paul M Speight; David A Isenberg
Vascular cell adhesion molecule 1 and alpha 4 and beta 1 integrins in lymphocyte aggregates in Sjögren's syndrome and rheumatoid arthritis.
Annals of the rheumatic diseases 1993;52(11):806-11.
1993: B M Twomey; V Amin; David A Isenberg; David S Latchman
Elevated levels of the 70 kD heat shock protein in patients with systemic lupus erythematosus are not dependent on enhanced transcription of the hsp70 gene.
Lupus 1993;2(5):297-301.
1993: D M Keeling; A J Wilson; Ian J Mackie; David A Isenberg; S J Machin
Role of beta 2-glycoprotein I and anti-phospholipid antibodies in activation of protein C in vitro.
Journal of clinical pathology 1993;46(10):908-11.
1993: David A Isenberg
Immunological tests in autoimmune rheumatic disease.
British journal of hospital medicine 1993;50(6):315-20.
1993: B M Twomey; S McCallum; David A Isenberg; David S Latchman
Elevation of heat shock protein synthesis and hsp gene transcription during monocyte to macrophage differentiation of U937 cells.
Clinical and experimental immunology 1993;93(2):178-83.
1993: L S Teh; M K Lee; F Wang; M Manivasagar; P J Charles; G D Nicholson; E M Hay; David A Isenberg; Nick Amos; Bryan D Williams
Antiribosomal P protein antibodies in different populations of patients with systemic lupus erythematosus.
British journal of rheumatology 1993;32(8):663-5.
1993: B M Twomey; V B Dhillon; S McCallum; David A Isenberg; David S Latchman
Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene.
Journal of autoimmunity 1993;6(4):495-506.
1993: E M Hay; Paul A Bacon; C Gordon; David A Isenberg; P Maddison; M L Snaith; Deborah Symmons; N Viner; Asad Zoma
The BILAG index: a reliable and valid instrument for measuring clinical disease activity in systemic lupus erythematosus.
The Quarterly journal of medicine 1993;86(7):447-58.
1993: D M Keeling; A J Wilson; Ian J Mackie; David A Isenberg; S J Machin
Lupus anticoagulant activity of some antiphospholipid antibodies against phospholipid bound beta 2 glycoprotein I.
Journal of clinical pathology 1993;46(7):665-7.
1993: S Menon; M L Snaith; David A Isenberg
The association of malignancy with SLE: an analysis of 150 patients under long-term review.
Lupus 1993;2(3):177-81.
1993: V B Dhillon; S McCallum; P Norton; B M Twomey; F Erkeller-Yuksel; Peter M Lydyard; David A Isenberg; D S Latchman
Differential heat shock protein overexpression and its clinical relevance in systemic lupus erythematosus.
Annals of the rheumatic diseases 1993;52(6):436-42.
1993: M R Ehrenstein; M Swana; D Keeling; R Asherson; G R Hughes; David A Isenberg
Anti-DNA antibodies in the primary antiphospholipid syndrome (PAPS)
British journal of rheumatology 1993;32(5):362-5.
1993: E M Hay; David A Isenberg
Autoantibodies in central nervous system lupus.
British journal of rheumatology 1993;32(4):329-32.
1993: M Ehrenstein; C Longhurst; David A Isenberg
Production and analysis of IgG monoclonal anti-DNA antibodies from systemic lupus erythematosus (SLE) patients.
Clinical and experimental immunology 1993;92(1):39-45.
1993: M R Ehrenstein; E McSweeney; M Swane; C P Worman; Anthony H Goldstone; David A Isenberg
Appearance of anti-DNA antibodies in patients treated with interferon-alpha.
Arthritis and rheumatism 1993;36(2):279-80.
1992: F M Erkeller-Yüksel; David A Isenberg; V B Dhillon; David S Latchman; Peter M Lydyard
Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus.
Journal of autoimmunity 1992;5(6):803-14.
1992: B Knight; David R Katz; David A Isenberg; M A Ibrahim; S Le Page; Patricia Hutchings; Robert S Schwartz; Anne Cooke
Induction of adjuvant arthritis in mice.
Clinical and experimental immunology 1992;90(3):459-65.
1992: F Blanco; Jatinderpal Kalsi; Chelliah T Ravirajan; Paul M Speight; A R Bradwell; David A Isenberg
IgG subclasses in systemic lupus erythematosus and other autoimmune rheumatic diseases.
Lupus 1992;1(6):391-9.
1992: D M Keeling; A J Wilson; Ian J Mackie; S J Machin; David A Isenberg
Some 'antiphospholipid antibodies' bind to beta 2-glycoprotein I in the absence of phospholipid.
British journal of haematology 1992;82(3):571-4.
1992: M R Ehrenstein; David A Isenberg
Hypergammaglobulinaemia and autoimmune rheumatic diseases.
Annals of the rheumatic diseases 1992;51(11):1185-7.
1992: K B Bodman; N Sumar; L E Mackenzie; David A Isenberg; Frank C Hay; Ivan M Roitt; Peter M Lydyard
Lymphocytes from patients with rheumatoid arthritis produce agalactosylated IgG in vitro.
Clinical and experimental immunology 1992;88(3):420-3.
1992: V B Dhillon; D M Keeling; G L Ridgway; M L Snaith; David A Isenberg
Treponemal infection coexisting with systemic lupus erythematosus.
British journal of rheumatology 1992;31(5):345-8.
1992: L S Teh; A E Bedwell; David A Isenberg; C Gordon; P Emery; P J Charles; M Harper; Nick Amos; Bryan D Williams
Antibodies to protein P in systemic lupus erythematosus.
Annals of the rheumatic diseases 1992;51(4):489-94.
1992: J S Axford; N Sumar; Azita Alavi; David A Isenberg; A Young; K B Bodman; Ivan M Roitt
Changes in normal glycosylation mechanisms in autoimmune rheumatic disease.
The Journal of clinical investigation 1992;89(3):1021-31.
1992: A J MacGregor; V B Dhillon; A Binder; C A Forte; B C Knight; D J Betteridge; David A Isenberg
Fasting lipids and anticardiolipin antibodies as risk factors for vascular disease in systemic lupus erythematosus.
Annals of the rheumatic diseases 1992;51(2):152-5.
1992: M R Ehrenstein; M L Snaith; David A Isenberg
Idiopathic myositis: a rheumatological view.
Annals of the rheumatic diseases 1992;51(1):41-4.
1992: A J MacGregor; Jatinderpal Kalsi; Chelliah T Ravirajan; B Leaker; R Watts; H Winska-Wiloch; B Knight; Anthony G W Norden; David A Isenberg; Geraldine Cambridge
Analysis of antibody reactivity in the sera of 42 patients with paraproteinaemia.
Autoimmunity 1992;13(2):101-5.
1992: Jatinderpal Kalsi; David A Isenberg
Immortalisation of human antibody producing cells.
Autoimmunity 1992;13(3):249-58.
1991: David A Isenberg; D Katz; S Le Page; B Knight; L Tucker; P Maddison; Patricia Hutchings; R Watts; J André-Schwartz; Robert S Schwartz
Independent analysis of the 16/6 idiotype lupus model. A role for an environmental factor?
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4172-7.
1991: N Sumar; C B Colaço; K B Bodman; R Parekh; P Williams; Raymond A Dwek; T Rademacher; David A Isenberg; A Soltys; Frank C Hay
Abnormalities in the glycosylation of IgG in spouses of patients with rheumatoid arthritis. A family study.
Journal of autoimmunity 1991;4(6):907-14.
1991: Richard Watts; J L Hillson; I R Oppliger; L Mackenzie; Peter M Lydyard; C G Mackworth Young; C Brown; Norman A Staines; David A Isenberg
Sequence analysis and idiotypic relationships of BEG-2, a human fetal antibody reactive with DNA.
Lupus 1991;1(1):9-17.
1991: F Blanco; Jatinderpal Kalsi; David A Isenberg
Analysis of antibodies to RNA in patients with systemic lupus erythematosus and other autoimmune rheumatic diseases.
Clinical and experimental immunology 1991;86(1):66-70.
1991: N Sumar; David A Isenberg; K B Bodman; A Soltys; A Young; A M Leak; J Round; Frank C Hay; Ivan M Roitt
Reduction in IgG galactose in juvenile and adult onset rheumatoid arthritis measured by a lectin binding method and its relation to rheumatoid factor.
Annals of the rheumatic diseases 1991;50(9):607-10.
1991: L Turner-Stokes; D Jones; K G Patterson; A Todd-Pokropek; David A Isenberg; A H Goldstone
Measurement of haematological indices of chronic rheumatic disease with two newer generation automated systems, the H1 and H6000 (Technicon).
Annals of the rheumatic diseases 1991;50(8):583-7.
1991: A J Walton; M L Snaith; MF Locniskar; A G Cumberland; W J Morrow; David A Isenberg
Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 1991;50(7):463-6.
1991: D M Keeling; S J Campbell; Ian J Mackie; S J Machin; David A Isenberg
The fibrinolytic response to venous occlusion and the natural anticoagulants in patients with antiphospholipid antibodies both with and without systemic lupus erythematosus.
British journal of haematology 1991;77(3):354-9.
1991: C Pilcher; W Williams; David A Isenberg
Assessment of common idiotype PR4-Id in serial bleeds from lupus patients.
Autoimmunity 1991;9(1):7-12.
1990: Richard Watts; David A Isenberg
Autoantibodies and antibacterial antibodies: from both sides now.
Annals of the rheumatic diseases 1990;49(12):961-5.
1990: D M Keeling; S J Campbell; Ian J Mackie; S J Machin; David A Isenberg
Total and free protein S in systemic lupus erythematosus.
Thrombosis research 1990;60(3):237-40.
1990: David A Isenberg
Autoantibodies and their idiotypes.
Current opinion in rheumatology 1990;2(5):724-32.
1990: V B Dhillon; M C Davies; M L Hall; J M Round; P J Ell; H S Jacobs; M L Snaith; David A Isenberg
Assessment of the effect of oral corticosteroids on bone mineral density in systemic lupus erythematosus: a preliminary study with dual energy x ray absorptiometry.
Annals of the rheumatic diseases 1990;49(8):624-6.
1990: David A Isenberg; Norman A Staines
DNA antibody idiotypes. An analysis of their role in health and disease.
Journal of autoimmunity 1990;3(4):339-55; discussion 355-6.
1990: N Sumar; K B Bodman; T W Rademacher; Raymond A Dwek; P Williams; R B Parekh; J Edge; Graham Rook; David A Isenberg; Frank C Hay
Analysis of glycosylation changes in IgG using lectins.
Journal of immunological methods 1990;131(1):127-36.
1990: Richard Watts; Chelliah T Ravirajan; Norman A Staines; David A Isenberg
A human fetal monoclonal DNA-binding antibody shares idiotypes with fetal and adult murine monoclonal DNA-binding antibodies.
Immunology 1990;69(3):348-54.
1990: Joyce Rauch; M Hazeltine; H Tannenbaum; DS Danoff; David A Isenberg; J Wild; John S Sampalis; John M Esdaile
Association of anti-DNA idiotype markers with clinical and serological manifestations in patients with systemic lupus erythematosus.
The Journal of rheumatology 1990;17(2):178-85.
1990: Richard Watts; H Winska-Wiloch; S Muller; David A Isenberg
Analysis of factors affecting human hybridoma production.
Human antibodies and hybridomas 1990;1(3):160-5.
1990: S H Le Page; C Dudeney; S Shall; Y Shoenfeld; David A Isenberg
Disease specificity of antibodies to poly (ADP-ribose); their relationships to anti-DNA antibodies and to disease activity in lupus.
Autoimmunity 1990;5(3):169-77.
1989: Richard Watts; David A Isenberg
Pancreatic disease in the autoimmune rheumatic disorders.
Seminars in arthritis and rheumatism 1989;19(3):158-65.
1989: A Binder; P J Maddison; P Skinner; A Kurtz; David A Isenberg
Sjögren's syndrome: association with type-1 diabetes mellitus.
British journal of rheumatology 1989;28(6):518-20.
1989: M A Thomas; G Frampton; David A Isenberg; Y Shoenfeld; A Akinsola; M Ramzy; J Lilleywhite; D G Williams
A common anti-DNA antibody idiotype and anti-phospholipid antibodies in sera from patients with schistosomiasis and filariasis with and without nephritis.
Journal of autoimmunity 1989;2(6):803-11.
1989: G Tsoulfa; Graham Rook; G M Bahr; M A Sattar; K Behbehani; D B Young; A Mehlert; J D Van-Embden; Frank C Hay; David A Isenberg
Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis.
Scandinavian journal of immunology 1989;30(5):519-27.
1989: Richard Watts; W Williams; S Le Page; Anthony G W Norden; A Soltys; G Swana; I Addison; Frank C Hay; David A Isenberg
Analysis of autoantibody reactivity and common idiotype PR4 expression of myeloma proteins.
Journal of autoimmunity 1989;2(5):689-700.
1989: S H Le Page; W Williams; D Parkhouse; Geraldine Cambridge; L MacKenzie; Peter M Lydyard; David A Isenberg
Relation between lymphocytotoxic antibodies, anti-DNA antibodies and a common anti-DNA antibody idiotype PR4 in patients with systemic lupus erythematosus, their relatives and spouses.
Clinical and experimental immunology 1989;77(3):314-8.
1989: P M Norton; David A Isenberg; David S Latchman
Elevated levels of the 90 kd heat shock protein in a proportion of SLE patients with active disease.
Journal of autoimmunity 1989;2(2):187-95.
1989: G Tsoulfa; Graham Rook; J D Van-Embden; D B Young; A Mehlert; David A Isenberg; Frank C Hay; Peter M Lydyard
Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis.
Annals of the rheumatic diseases 1989;48(2):118-23.
1989: J S Axford; K Bodman; Frank C Hay; David A Isenberg; Peter M Lydyard; L Mackenzie; Ivan M Roitt; N Sumar; Graham Rook; Raymond A Dwek
Comment on the article by Tomana et al.
Arthritis and rheumatism 1989;32(2):235-6.
1989: L Turner-Stokes; M Jones; I Addison; M Mansell; David A Isenberg
Does rheumatoid factor protect lupus patients from the development of nephritis?
Annals of the rheumatic diseases 1989;48(1):14-6.
1988: David A Isenberg; W Williams; S Le Page; G Swana; R Feldman; I Addison; R Bakimer; Y Shoenfeld
A comparison of autoantibodies and common DNA antibody idiotypes in SLE patients and their spouses.
British journal of rheumatology 1988;27(6):431-5.
1988: Deborah Symmons; J S Coppock; Paul A Bacon; B Bresnihan; David A Isenberg; P Maddison; N McHugh; M L Snaith; Asad Zoma
Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus. Members of the British Isles Lupus Assessment Group (BILAG).
The Quarterly journal of medicine 1988;69(259):927-37.
1988: M E Devey; S R Lee; S Le Page; R Feldman; David A Isenberg
Serial studies of the IgG subclass and functional affinity of DNA antibodies in systemic lupus erythematosus.
Journal of autoimmunity 1988;1(5):483-94.
1988: David A Isenberg; C Dudeney; W Williams; A Todd-Pokropek; B D Stollar
Disease activity in systemic lupus erythematosus related to a range of antibodies binding DNA and synthetic polynucleotides.
Annals of the rheumatic diseases 1988;47(9):717-24.
1988: Richard Watts; David A Isenberg
Idiotypes and anti-idiotypes: what are they trying to tell us?
Annals of the rheumatic diseases 1988;47(9):705-7.
1988: W Williams; A Zumla; R Behrens; M Locniskar; A Voller; Keith P W J McAdam; David A Isenberg
Studies of a common idiotype PR4 in autoimmune rheumatic disease.
Arthritis and rheumatism 1988;31(9):1097-104.
1988: L Turner-Stokes; David A Isenberg
Immunisation of patients with rheumatoid arthritis and systemic lupus erythematosus.
Annals of the rheumatic diseases 1988;47(7):529-31.
1988: M Locniskar; A Zumla; D W Mudd; David A Isenberg; W Williams; Keith P W J McAdam
Human monoclonal antibodies to phenolic glycolipid-I derived from patients with leprosy, and production of specific anti-idiotypes.
Immunology 1988;64(2):245-51.
1988: D A Yardumian; David A Isenberg; M H A Rustin; G Belcher; M L Snaith; P M Dowd; S J Machin
Successful treatment of Raynaud's syndrome with Iloprost, a chemically stable prostacyclin analogue.
British journal of rheumatology 1988;27(3):220-6.
1988: David A Isenberg; Y Shoenfeld
An analysis of autoimmunity through studies of DNA antibody idiotypes.
Autoimmunity 1988;1(1):67-75.
1987: J S Axford; L Mackenzie; Peter M Lydyard; Frank C Hay; David A Isenberg; I M Roitt
Reduced B-cell galactosyltransferase activity in rheumatoid arthritis.
Lancet 1987;2(8574):1486-8.
1987: David A Isenberg; P J Maddison
Detection of antibodies to double stranded DNA and extractable nuclear antigen.
Journal of clinical pathology 1987;40(11):1374-81.
1987: J C W Edwards; M L Snaith; David A Isenberg
A double blind controlled trial of methylprednisolone infusions in systemic lupus erythematosus using individualised outcome assessment.
Annals of the rheumatic diseases 1987;46(10):773-6.
1987: PJ Roberts; David A Isenberg; Anthony W Segal
Defective degradation of bacterial DNA by phagocytes from patients with systemic and discoid lupus erythematosus.
Clinical and experimental immunology 1987;69(1):68-78.
1987: M E Devey; K Bleasdale; David A Isenberg
Antibody affinity and IgG subclass of responses to tetanus toxoid in patients with rheumatoid arthritis and systemic lupus erythematosus.
Clinical and experimental immunology 1987;68(3):562-9.
1987: David A Isenberg; C Dudeney; W Williams; I Addison; S Charles; J Clarke; A Todd-Pokropek
Measurement of anti-DNA antibodies: a reappraisal using five different methods.
Annals of the rheumatic diseases 1987;46(6):448-56.
1987: David A Isenberg; P Maddison; G Swana; R P Skinner; M Swana; M Jones; I Addison; C Dudeney; S Shall; A el Roiey
Profile of autoantibodies in the serum of patients with tuberculosis, klebsiella and other gram-negative infections.
Clinical and experimental immunology 1987;67(3):516-23.
1986: C Dudeney; Y Shoenfeld; J Rauch; M Jones; C Mackworth Young; M Tavassoli; S Shall; David A Isenberg
A study of anti-poly (ADP-ribose) antibodies and an anti-DNA antibody idiotype and other immunological abnormalities in lupus family members.
Annals of the rheumatic diseases 1986;45(6):502-7.
1986: David A Isenberg; P Martin; V Hajirousou; A Todd-Pokropek; A H Goldstone; M L Snaith
Haematological reassessment of rheumatoid arthritis using an automated method.
British journal of rheumatology 1986;25(2):152-7.
1986: A W Segal; David A Isenberg; V Hajirousou; S Tolfree; J Clark; M L Snaith
Preliminary evidence for gut involvement in the pathogenesis of rheumatoid arthritis?
British journal of rheumatology 1986;25(2):162-6.
1986: David A Isenberg; C B Colaco; C Dudeney; A Todd-Pokropek; M L Snaith
The relationship of anti-DNA antibody idiotypes and anti-cardiolipin antibodies to disease activity in systemic lupus erythematosus.
Medicine 1986;65(1):46-55.
1985: David A Isenberg; Y Shoenfeld; Mark J Walport; C Mackworth-Young; C Dudeney; A Todd-Pokropek; S Brill; A Weinberger; J Pinkas
Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives.
Arthritis and rheumatism 1985;28(9):999-1007.
1982: W J Morrow; David A Isenberg; H F Parry; L Shen; E E Okolie; F Farzaneh; S Shall; M L Snaith
Studies on autoantibodies to poly (adenosine diphosphate-ribose) in SLE and other autoimmune diseases.
Annals of the rheumatic diseases 1982;41(4):396-402.
1982: W J Morrow; David A Isenberg; A Todd-Pokropek; H F Parry; M L Snaith
Useful laboratory measurements in the management of systemic lupus erythematosus.
The Quarterly journal of medicine 1982;51(202):125-38.
1982: David A Isenberg; K G Patterson; A Todd-Pokropek; M L Snaith; A H Goldstone
Haematological aspects of systemic lupus erythematosus: a reappraisal using automated methods.
Acta haematologica 1982;67(4):242-8.
1981: W J Morrow; David A Isenberg; H F Parry; M L Snaith
C-reactive protein in sera from patients with systemic lupus erythematosus.
The Journal of rheumatology 1981;8(4):599-604.