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Kazuhiko Ishihara

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Botao Gao; Tomohiro Konno; Kazuhiko Ishihara
A simple procedure for the preparation of precise spatial multicellular phospholipid polymer hydrogels.
Yoshiharu Asanuma; Yuuki Inoue; Shin-Ichi Yusa; Kazuhiko Ishihara
Hybridization of poly(2-methacryloyloxyethyl phosphorylcholine-block-2-ethylhexyl methacrylate) with segmented polyurethane for reducing thrombogenicity.
Ji-Hun Seo; Tetsuji Yamaoka; Yuuki Inoue; Kazuhiko Ishihara; Sachiro Kakinoki; Nobuhiko Yui
Inducing Rapid Cellular Response on RGD-Binding Threaded Macromolecular Surfaces.

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2013: Botao Gao; Tomohiro Konno; Kazuhiko Ishihara
A simple procedure for the preparation of precise spatial multicellular phospholipid polymer hydrogels.
Colloids and surfaces. B, Biointerfaces 2013;108():345-51.
2013: Yoshiharu Asanuma; Yuuki Inoue; Shin-Ichi Yusa; Kazuhiko Ishihara
Hybridization of poly(2-methacryloyloxyethyl phosphorylcholine-block-2-ethylhexyl methacrylate) with segmented polyurethane for reducing thrombogenicity.
Colloids and surfaces. B, Biointerfaces 2013;108():239-45.
2013: Ji-Hun Seo; Tetsuji Yamaoka; Yuuki Inoue; Kazuhiko Ishihara; Sachiro Kakinoki; Nobuhiko Yui
Inducing Rapid Cellular Response on RGD-Binding Threaded Macromolecular Surfaces.
Journal of the American Chemical Society 2013;135(15):5513-6.
2013: Ji-Hun Seo; Tetsuji Yamaoka; Yuuki Inoue; Kazuhiko Ishihara; Sachiro Kakinoki; Akio Kishida; Kwangwoo Nam; Nobuhiko Yui
The significance of hydrated surface molecular mobility in the control of the morphology of adhering fibroblasts.
Biomaterials 2013;34(13):3206-14.
2013: So-Yoon Lee; Ryosuke Matsuno; Kazuhiko Ishihara; Madoka Takai
Direct electron transfer with enzymes on nanofiliform titanium oxide films with electron-transport ability.
Biosensors & bioelectronics 2013;41():289-93.
2013: Batzaya Byambaa; Tomohiro Konno; Kazuhiko Ishihara
Detachment of cells adhered on the photoreactive phospholipid polymer surface by photoirradiation and their functionality.
Colloids and surfaces. B, Biointerfaces 2013;103():489-95.
2013: Kyoko Fukazawa; Qiang Li; Stefan Seeger; Kazuhiko Ishihara
Direct observation of selective protein capturing on molecular imprinting substrates.
Biosensors & bioelectronics 2013;40(1):96-101.
2013: Xiaojie Lin; Madoka Takai; Tomohiro Konno; Kazuhiko Ishihara
Redox phospholipid polymer microparticles as doubly functional polymer support for immobilization of enzyme oxidase.
Colloids and surfaces. B, Biointerfaces 2013;102():857-63.
2012: Yusuke Abe; Kyoko Fukazawa; Kazuyoshi Fukunaga; Yusuke Inoue; Kazuhiko Ishihara; Kohei Ishii; Takashi Isoyama; Hidemoto Nakagawa; Emiko Nakano; Minoru Ono; Toshiya Ono; Itsuro Saito; Kou Imachi
The helical flow pump with a hydrodynamic levitation impeller.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(4):331-40.
2012: Xiaojie Lin; Koichi Nishio; Tomohiro Konno; Kazuhiko Ishihara
The effect of the encapsulation of bacteria in redox phospholipid polymer hydrogels on electron transfer efficiency in living cell-based devices.
Biomaterials 2012;33(33):8221-7.
2012: Batzaya Byambaa; Tomohiro Konno; Kazuhiko Ishihara
Cell adhesion control on photoreactive phospholipid polymer surfaces.
Colloids and surfaces. B, Biointerfaces 2012;99():1-6.
2012: Surasak Chantasirichot; Kazuhiko Ishihara
Electrospun phospholipid polymer substrate for enhanced performance in immunoassay system.
Biosensors & bioelectronics 2012;38(1):209-14.
2012: Kyoko Fukazawa; Kazuhiko Ishihara
Simple surface treatment using amphiphilic phospholipid polymers to obtain wetting and lubricity on polydimethylsiloxane-based substrates.
Colloids and surfaces. B, Biointerfaces 2012;97():70-6.
2012: Masayuki Kyomoto; Toru Moro; Kenichi Saiga; Yoshio Takatori; Masami Hashimoto; Hideya Ito; Hiroshi Kawaguchi; Kazuhiko Ishihara
Biomimetic hydration lubrication with various polyelectrolyte layers on cross-linked polyethylene orthopedic bearing materials.
Biomaterials 2012;33(18):4451-9.
2012: Ziyin Li; Madoka Takai; Tomohiro Konno; Kazuhiko Ishihara
Fabrication of polymeric electron-transfer mediator/enzyme hydrogel multilayer on an Au electrode in a layer-by-layer process.
Biosensors & bioelectronics 2012;34(1):191-6.
2012: Tatsuo Aikawa; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Spherical phospholipid polymer hydrogels for cell encapsulation prepared with a flow-focusing microfluidic channel device.
Langmuir : the ACS journal of surfaces and colloids 2012;28(4):2145-50.
2012: Jiyeon Choi; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Regulation of cell proliferation by multi-layered phospholipid polymer hydrogel coatings through controlled release of paclitaxel.
Biomaterials 2012;33(3):954-61.
2012: Yuuki Inoue; Kazuhiko Ishihara; Lin Ye; Nobuhiko Yui
Preparation and surface properties of polyrotaxane-containing tri-block copolymers as a design for dynamic biomaterials surfaces.
Colloids and surfaces. B, Biointerfaces 2012;89():223-7.
2011: Ye Yao; Kyoko Fukazawa; Nan Huang; Kazuhiko Ishihara
Effects of 3,4-dihydrophenyl groups in water-soluble phospholipid polymer on stable surface modification of titanium alloy.
Colloids and surfaces. B, Biointerfaces 2011;88(1):215-20.
2011: Eri Ohto-Fujita; Takashi Sakurai; Miho Shimizu; Toshihiro Sugitate; Kaori Taniwaki; Kotaro Yoshimura; Yukio Hasebe; Kazuhiko Ishihara; Tomohiro Konno; Jun Miyake; Yoriko Atomi
Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts.
Cell and tissue research 2011;345(1):177-90.
2011: Ji-Hun Seo; Ryosuke Matsuno; Yan Lee; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Effect of hydrophilic polymer conjugation on heat-induced conformational changes in a protein.
Acta biomaterialia 2011;7(4):1477-84.
2011: Hyung Il Kim; Kazuhiko Ishihara; Seungbok Lee; Ji-Hun Seo; Hye Young Kim; Dongwhan Suh; Min Uk Kim; Tomohiro Konno; Madoka Takai; Jeong-Sun Seo
Tissue response to poly(L-lactic acid)-based blend with phospholipid polymer for biodegradable cardiovascular stents.
Biomaterials 2011;32(9):2241-7.
2011: Kazuhiko Ishihara; Yusuke Goto; Madoka Takai; Ryosuke Matsuno; Yuuki Inoue; Tomohiro Konno
Novel polymer biomaterials and interfaces inspired from cell membrane functions.
Biochimica et biophysica acta 2011;1810(3):268-75.
2011: Noriyuki Ishiyama; Toru Moro; Takashi Ohe; Toshiki Miura; Kazuhiko Ishihara; Tomohiro Konno; Tadashi Ohyama; Mizuna Kimura; Masayuki Kyomoto; Taku Saito; Kozo Nakamura; Hiroshi Kawaguchi
Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.
The Journal of bone and joint surgery. American volume 2011;93(2):142-9.
2011: Takao Kamei; Joji Kitayama; Hironori Yamaguchi; Daisuke Soma; Shigenobu Emoto; Tomohiro Konno; Kazuhiko Ishihara; Hironori Ishigami; Shoichi Kaisaki; Hirokazu Nagawa
Spatial distribution of intraperitoneally administrated paclitaxel nanoparticles solubilized with poly (2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) in peritoneal metastatic nodules.
Cancer science 2011;102(1):200-5.
2010: Yan Xu; Kihoon Jang; Tomohiro Konno; Kazuhiko Ishihara; Kazuma Mawatari; Takehiko Kitamori
The biological performance of cell-containing phospholipid polymer hydrogels in bulk and microscale form.
Biomaterials 2010;31(34):8839-46.
2010: Yuuki Inoue; Kazuhiko Ishihara
Reduction of protein adsorption on well-characterized polymer brush layers with varying chemical structures.
Colloids and surfaces. B, Biointerfaces 2010;81(1):350-7.
2010: Aya Saito; Tomohiro Konno; Hiroki Ikake; Kimio Kurita; Kazuhiko Ishihara
Control of cell function on a phospholipid polymer having phenylboronic acid moiety.
Biomedical materials (Bristol, England) 2010;5(5):054101.
2010: Toru Moro; Yoshio Takatori; Masayuki Kyomoto; Kazuhiko Ishihara; K Saiga; Kozo Nakamura; Hiroshi Kawaguchi
Surface grafting of biocompatible phospholipid polymer MPC provides wear resistance of tibial polyethylene insert in artificial knee joints.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2010;18(9):1174-82.
2010: Sang-Ho YE; Carl A Johnson; Joshua R Woolley; Hironobu Murata; Lara J Gamble; Kazuhiko Ishihara; William R Wagner
Simple surface modification of a titanium alloy with silanated zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity.
Colloids and surfaces. B, Biointerfaces 2010;79(2):357-64.
2010: Kihoon Jang; Kae Sato; Yo Tanaka; Yan Xu; Moritoshi Sato; Takahiro Nakajima; Kazuma Mawatari; Tomohiro Konno; Kazuhiko Ishihara; Takehiko Kitamori
An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel.
Lab on a chip 2010;10(15):1937-45.
2010: Yan Xu; Kae Sato; Kazuma Mawatari; Tomohiro Konno; Kihoon Jang; Kazuhiko Ishihara; Takehiko Kitamori
A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions.
Advanced materials (Deerfield Beach, Fla.) 2010;22(28):3017-21.
2010: Yan Xu; Madoka Takai; Kazuhiko Ishihara
Phospholipid Polymer Biointerfaces for Lab-on-a-Chip Devices.
Annals of biomedical engineering 2010;38(6):1938-53.
2010: Kazuki Nishizawa; Madoka Takai; Kazuhiko Ishihara
Stabilization of phospholipid polymer surface with three-dimensional nanometer-scaled structure for highly sensitive immunoassay.
Colloids and surfaces. B, Biointerfaces 2010;77(2):263-9.
2010: Noriyuki Ishiyama; Toru Moro; Kazuhiko Ishihara; Takashi Ohe; Toshiki Miura; Tomohiro Konno; Tadashi Ohyama; Mizuna Kimura; Masayuki Kyomoto; Kozo Nakamura; Hiroshi Kawaguchi
The prevention of peritendinous adhesions by a phospholipid polymer hydrogel formed in situ by spontaneous intermolecular interactions.
Biomaterials 2010;31(14):4009-16.
2010: Takanori Shimizu; Tatsuro Goda; Norihiko Minoura; Madoka Takai; Kazuhiko Ishihara
Super-hydrophilic silicone hydrogels with interpenetrating poly(2-methacryloyloxyethyl phosphorylcholine) networks.
Biomaterials 2010;31(12):3274-80.
2010: G Liu; K Iwata; Toru Ogasawara; Junji Watanabe; K Fukazawa; Kazuhiko Ishihara; Y Asawa; Y Fujihara; U-L Chung; Toru Moro; Yoshio Takatori; Tsuyoshi Takato; Kozo Nakamura; Hiroshi Kawaguchi; Kazuto Hoshi
Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates.
Journal of biomedical materials research. Part A 2010;92(4):1273-82.
2010: Tatsuro Goda; Yusuke Goto; Kazuhiko Ishihara
Cell-penetrating macromolecules: direct penetration of amphipathic phospholipid polymers across plasma membrane of living cells.
Biomaterials 2010;31(8):2380-7.
2010: Masayuki Kyomoto; Toru Moro; Yoshio Takatori; Hiroshi Kawaguchi; Kozo Nakamura; Kazuhiko Ishihara
Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine) on poly(ether-ether-ketone).
Biomaterials 2010;31(6):1017-24.
2010: Masayuki Kyomoto; Toru Moro; Ken-ichi Saiga; Fumiaki Miyaji; Hiroshi Kawaguchi; Yoshio Takatori; Kozo Nakamura; Kazuhiko Ishihara
Lubricity and stability of poly(2-methacryloyloxyethyl phosphorylcholine) polymer layer on Co-Cr-Mo surface for hemi-arthroplasty to prevent degeneration of articular cartilage.
Biomaterials 2010;31(4):658-68.
2009: Kentaro Shirai; Björn Renberg; Kae Sato; Kazuma Mawatari; Tomohiro Konno; Kazuhiko Ishihara; Takehiko Kitamori
Graft linker immobilization for spatial control of protein immobilization inside fused microchips.
Electrophoresis 2009;30(24):4251-5.
2009: Kyoko Fukazawa; Kazuhiko Ishihara
Fabrication of a cell-adhesive protein imprinting surface with an artificial cell membrane structure for cell capturing.
Biosensors & bioelectronics 2009;25(3):609-14.
2009: Toru Moro; Yoshio Takatori; Kazuhiko Ishihara; Masayuki Kyomoto; Kozo Nakamura; Hiroshi Kawaguchi
[Progress of research in osteoarthritis. Invention of longer lasting artificial joints].
Clinical calcium 2009;19(11):1629-37.
2009: Kazuhiko Kitano; Yuuki Inoue; Ryosuke Matsuno; Madoka Takai; Kazuhiko Ishihara
Nanoscale evaluation of lubricity on well-defined polymer brush surfaces using QCM-D and AFM.
Colloids and surfaces. B, Biointerfaces 2009;74(1):350-7.
2009: Daisuke Soma; Joji Kitayama; Tomohiro Konno; Kazuhiko Ishihara; Jun Yamada; Takao Kamei; Hironori Ishigami; Shoichi Kaisaki; Hirokazu Nagawa
Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer.
Cancer science 2009;100(10):1979-85.
2009: Ji-Hun Seo; Ryosuke Matsuno; Madoka Takai; Kazuhiko Ishihara
Cell adhesion on phase-separated surface of block copolymer composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(dimethylsiloxane).
Biomaterials 2009;30(29):5330-40.
2009: Jiyeon Choi; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Controlled drug release from multilayered phospholipid polymer hydrogel on titanium alloy surface.
Biomaterials 2009;30(28):5201-8.
2009: Yan Xu; Madoka Takai; Kazuhiko Ishihara
Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces.
Biomaterials 2009;30(28):4930-8.
2009: Ji-Hun Seo; Ryosuke Matsuno; Yan Lee; Madoka Takai; Kazuhiko Ishihara
Conformational recovery and preservation of protein nature from heat-induced denaturation by water-soluble phospholipid polymer conjugation.
Biomaterials 2009;30(28):4859-67.
2009: Takanori Kihara; Chikashi Nakamura; Miho Suzuki; Sung-Woong Han; Kyoko Fukazawa; Kazuhiko Ishihara; Jun Miyake
Development of a method to evaluate caspase-3 activity in a single cell using a nanoneedle and a fluorescent probe.
Biosensors & bioelectronics 2009;25(1):22-7.
2009: Kazuhiko Ishihara; Madoka Takai
Bioinspired interface for nanobiodevices based on phospholipid polymer chemistry.
Journal of the Royal Society, Interface / the Royal Society 2009;6 Suppl 3():S279-91.
2009: Hyung Il Kim; Madoka Takai; Kazuhiko Ishihara
Bioabsorbable material-containing phosphorylcholine group-rich surfaces for temporary scaffolding of the vessel wall.
Tissue engineering. Part C, Methods 2009;15(2):125-33.
2009: Toru Moro; Hiroshi Kawaguchi; Kazuhiko Ishihara; Masayuki Kyomoto; Tatsuro Karita; Hideya Ito; Kozo Nakamura; Yoshio Takatori
Wear resistance of artificial hip joints with poly(2-methacryloyloxyethyl phosphorylcholine) grafted polyethylene: comparisons with the effect of polyethylene cross-linking and ceramic femoral heads.
Biomaterials 2009;30(16):2995-3001.
2009: Tatsuro Goda; Ryosuke Matsuno; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Protein adsorption resistance and oxygen permeability of chemically crosslinked phospholipid polymer hydrogel for ophthalmologic biomaterials.
Journal of biomedical materials research. Part B, Applied biomaterials 2009;89(1):184-90.
2009: Masayuki Kyomoto; Kazuhiko Ishihara
Self-initiated surface graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on poly(ether ether ketone) by photoirradiation.
ACS applied materials & interfaces 2009;1(3):537-42.
2009: Kihoon Jang; Kae Sato; Kazuma Mawatari; Tomohiro Konno; Kazuhiko Ishihara; Takehiko Kitamori
Surface modification by 2-methacryloyloxyethyl phosphorylcholine coupled to a photolabile linker for cell micropatterning.
Biomaterials 2009;30(7):1413-20.
2009: Yan Xu; Madoka Takai; Kazuhiko Ishihara
Suppression of protein adsorption on a charged phospholipid polymer interface.
Biomacromolecules 2009;10(2):267-74.
2009: Ryosuke Matsuno; Yusuke Goto; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Controllable nanostructured surface modification on quantum dot for biomedical application in aqueous medium.
Journal of nanoscience and nanotechnology 2009;9(1):358-65.
2008: Jiyeon Choi; Tomohiro Konno; Ryosuke Matsuno; Madoka Takai; Kazuhiko Ishihara
Surface immobilization of biocompatible phospholipid polymer multilayered hydrogel on titanium alloy.
Colloids and surfaces. B, Biointerfaces 2008;67(2):216-23.
2008: Yusuke Goto; Ryosuke Matsuno; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Artificial cell membrane-covered nanoparticles embedding quantum dots as stable and highly sensitive fluorescence bioimaging probes.
Biomacromolecules 2008;9(11):3252-7.
2008: Koji Futamura; Ryosuke Matsuno; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Rapid development of hydrophilicity and protein adsorption resistance by polymer surfaces bearing phosphorylcholine and naphthalene groups.
Langmuir : the ACS journal of surfaces and colloids 2008;24(18):10340-4.
2008: Tatsuro Goda; Ryosuke Matsuno; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Photografting of 2-methacryloyloxyethyl phosphorylcholine from polydimethylsiloxane: tunable protein repellency and lubrication property.
Colloids and surfaces. B, Biointerfaces 2008;63(1):64-72.
2008: Yusuke Goto; Ryosuke Matsuno; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Polymer nanoparticles covered with phosphorylcholine groups and immobilized with antibody for high-affinity separation of proteins.
Biomacromolecules 2008;9(3):828-33.
2008: Kiyohisa Fujii; Hiroko N Matsumoto; Yoshihisa Koyama; Yasuhiko Iwasaki; Kazuhiko Ishihara; Kazuo Takakuda
Prevention of biofilm formation with a coating of 2-methacryloyloxyethyl phosphorylcholine polymer.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2008;70(2):167-73.
2008: Kazuki Nishizawa; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Bioconjugated phospholipid polymer biointerface for enzyme-linked immunosorbent assay.
Biomacromolecules 2008;9(1):403-7.
2007: Katsuhiro Ohuchi; Hideo Hoshi; Yasuhiko Iwasaki; Kazuhiko Ishihara; Masaharu Yoshikawa; Shinya Ugaki; Kozo Ishino; Satoru Osaki; Yasuhiro Kotani; Shunji Sano; Setsuo Takatani
Feasibility of a tiny centrifugal blood pump (TinyPump) for pediatric extracorporeal circulatory support.
Artificial organs 2007;31(5):408-12.
2007: Tomohiro Konno; Kazuhiko Ishihara
Temporal and spatially controllable cell encapsulation using a water-soluble phospholipid polymer with phenylboronic acid moiety.
Biomaterials 2007;28(10):1770-7.
2007: Jongwon Park; Shigeru Kurosawa; Madoka Takai; Kazuhiko Ishihara
Antibody immobilization to phospholipid polymer layer on gold substrate of quartz crystal microbalance immunosensor.
Colloids and surfaces. B, Biointerfaces 2007;55(2):164-72.
2007: Makiko Goto; Takehiko Tsukahara; Kiichi Sato; Tomohiro Konno; Kazuhiko Ishihara; Kae Sato; Takehiko Kitamori
Nanometer-scale patterned surfaces for control of cell adhesion.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2007;23(3):245-7.
2007: Yan Xu; Madoka Takai; Tomohiro Konno; Kazuhiko Ishihara
Microfluidic flow control on charged phospholipid polymer interface.
Lab on a chip 2007;7(2):199-206.
2007: Tatsuro Goda; Tomohiro Konno; Madoka Takai; Kazuhiko Ishihara
Photoinduced phospholipid polymer grafting on Parylene film: advanced lubrication and antibiofouling properties.
Colloids and surfaces. B, Biointerfaces 2007;54(1):67-73.
2007: James Sibarani; Madoka Takai; Kazuhiko Ishihara
Surface modification on microfluidic devices with 2-methacryloyloxyethyl phosphorylcholine polymers for reducing unfavorable protein adsorption.
Colloids and surfaces. B, Biointerfaces 2007;54(1):88-93.
2007: Mizuna Kimura; Madoka Takai; Kazuhiko Ishihara
Tissue-compatible and adhesive polyion complex hydrogels composed of amphiphilic phospholipid polymers.
Journal of biomaterials science. Polymer edition 2007;18(5):623-40.
2007: Mizuna Kimura; Madoka Takai; Kazuhiko Ishihara
Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels.
Journal of biomedical materials research. Part A 2007;80(1):45-54.
2006: Toru Moro; Yoshio Takatori; Kazuhiko Ishihara; Kozo Nakamura; Hiroshi Kawaguchi
2006 Frank Stinchfield Award: grafting of biocompatible polymer for longevity of artificial hip joints.
Clinical orthopaedics and related research 2006;453():58-63.
2006: Tatsuro Goda; Tomohiro Konno; Madoka Takai; Toru Moro; Kazuhiko Ishihara
Biomimetic phosphorylcholine polymer grafting from polydimethylsiloxane surface using photo-induced polymerization.
Biomaterials 2006;27(30):5151-60.
2006: Tomomi Ito; Junji Watanabe; Madoka Takai; Tomohiro Konno; Yasuhiko Iwasaki; Kazuhiko Ishihara
Dual mode bioreactions on polymer nanoparticles covered with phosphorylcholine group.
Colloids and surfaces. B, Biointerfaces 2006;50(1):55-60.
2006: Hideto Ueda; Junji Watanabe; Tomohiro Konno; Madoka Takai; Akira Saito; Kazuhiko Ishihara
Asymmetrically functional surface properties on biocompatible phospholipid polymer membrane for bioartificial kidney.
Journal of biomedical materials research. Part A 2006;77(1):19-27.
2006: Tatsuro Goda; Kazuhiko Ishihara
Soft contact lens biomaterials from bioinspired phospholipid polymers.
Expert review of medical devices 2006;3(2):167-74.
2006: Sang Ho Ye; Junji Watanabe; Madoka Takai; Yasuhiko Iwasaki; Kazuhiko Ishihara
High functional hollow fiber membrane modified with phospholipid polymers for a liver assist bioreactor.
Biomaterials 2006;27(9):1955-62.
2006: Tomohiro Konno; Tomomi Ito; Madoka Takai; Kazuhiko Ishihara
Enzymatic photochemical sensing using luciferase-immobilized polymer nanoparticles covered with artificial cell membrane.
Journal of biomaterials science. Polymer edition 2006;17(12):1347-57.
2006: Junji Watanabe; Kazuhiko Ishihara
Sequential enzymatic reactions and stability of biomolecules immobilized onto phospholipid polymer nanoparticles.
Biomacromolecules 2006;7(1):171-5.
2005: Mizuna Kimura; Kikuko Fukumoto; Junji Watanabe; Madoka Takai; Kazuhiko Ishihara
Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers.
Biomaterials 2005;26(34):6853-62.
2005: Sang-Ho YE; Junji Watanabe; Madoka Takai; Yasuhiko Iwasaki; Kazuhiko Ishihara
Design of functional hollow fiber membranes modified with phospholipid polymers for application in total hemopurification system.
Biomaterials 2005;26(24):5032-41.
2005: Junji Watanabe; Kazuhiko Ishihara
Cell engineering biointerface focusing on cytocompatibility using phospholipid polymer with an isomeric oligo(lactic acid) segment.
Biomacromolecules 2005;6(3):1797-802.
2005: Tomomi Ito; Yasuhiko Iwasaki; Tadashi Narita; Kazunari Akiyoshi; Kazuhiko Ishihara
Cell separation in microcanal coated with electrically charged phospholipid polymers.
Colloids and surfaces. B, Biointerfaces 2005;41(2-3):175-80.
2004: Toru Moro; Yoshio Takatori; Kazuhiko Ishihara; Tomohiro Konno; Yorinobu Takigawa; Tomiharu Matsushita; Ung-il Chung; Kozo Nakamura; Hiroshi Kawaguchi
Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis.
Nature materials 2004;3(11):829-36.
2004: Kwangwoo Nam; Junji Watanabe; Kazuhiko Ishihara
The characteristics of spontaneously forming physically cross-linked hydrogels composed of two water-soluble phospholipid polymers for oral drug delivery carrier I: hydrogel dissolution and insulin release under neutral pH condition.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(3):261-70.
2004: Yuuki Inoue; Junji Watanabe; Kazuhiko Ishihara
Dynamic motion of phosphorylcholine groups at the surface of poly(2-methacryloyloxyethyl phosphorylcholine-random-2,2,2-trifluoroethyl methacrylate).
Journal of colloid and interface science 2004;274(2):465-71.
2004: Kwangwoo Nam; Junji Watanabe; Kazuhiko Ishihara
Modeling of swelling and drug release behavior of spontaneously forming hydrogels composed of phospholipid polymers.
International journal of pharmaceutics 2004;275(1-2):259-69.
2004: Keigo Takei; Tomohiro Konno; Junji Watanabe; Kazuhiko Ishihara
Regulation of enzyme-substrate complexation by a substrate conjugated with a phospholipid polymer.
Biomacromolecules 2004;5(3):858-62.
2004: Jongwon Park; Shigeru Kurosawa; Junji Watanabe; Kazuhiko Ishihara
Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymeric nanoparticle for immunoassay of C-reactive protein detection.
Analytical chemistry 2004;76(9):2649-55.
2004: Tomohiro Konno; Junji Watanabe; Kazuhiko Ishihara
Conjugation of enzymes on polymer nanoparticles covered with phosphorylcholine groups.
Biomacromolecules 2004;5(2):342-7.
2004: Kazuhiko Ishihara; Daisuke Nishiuchi; Junji Watanabe; Yasuhiko Iwasaki
Polyethylene/phospholipid polymer alloy as an alternative to poly(vinylchloride)-based materials.
Biomaterials 2004;25(6):1115-22.
2004: Tomoaki Uchiyama; Junji Watanabe; Kazuhiko Ishihara
Implantable polymeric artificial pancreas.
Journal of biomaterials science. Polymer edition 2004;15(10):1237-62.
2004: Yuuki Inoue; Junji Watanabe; Madoka Takai; Kazuhiko Ishihara
Surface characteristics of block-type copolymer composed of semi-fluorinated and phospholipid segments synthesized by living radical polymerization.
Journal of biomaterials science. Polymer edition 2004;15(9):1153-66.
2004: Sang-Ho YE; Junji Watanabe; Kazuhiko Ishihara
Cellulose acetate hollow fiber membranes blended with phospholipid polymer and their performance for hemopurification.
Journal of biomaterials science. Polymer edition 2004;15(8):981-1001.
2004: Mizuna Kimura; Kikuko Fukumoto; Junji Watanabe; Kazuhiko Ishihara
Hydrogen-bonding-driven spontaneous gelation of water-soluble phospholipid polymers in aqueous medium.
Journal of biomaterials science. Polymer edition 2004;15(5):631-44.
2004: Daisuke Miyamoto; Junji Watanabe; Kazuhiko Ishihara
Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability.
Biomaterials 2004;25(1):71-6.
2003: Tomoaki Uchiyama; Yoshihiro Kiritoshi; Junji Watanabe; Kazuhiko Ishihara
Degradation of phospholipid polymer hydrogel by hydrogen peroxide aiming at insulin release device.
Biomaterials 2003;24(28):5183-90.
2003: Sang-Ho YE; Junji Watanabe; Yasuhiko Iwasaki; Kazuhiko Ishihara
Antifouling blood purification membrane composed of cellulose acetate and phospholipid polymer.
Biomaterials 2003;24(23):4143-52.
2003: Tomohiro Konno; Junji Watanabe; Kazuhiko Ishihara
Enhanced solubility of paclitaxel using water-soluble and biocompatible 2-methacryloyloxyethyl phosphorylcholine polymers.
Journal of biomedical materials research. Part A 2003;65(2):209-14.
2003: Junji Watanabe; Kazuhiko Ishihara
Phosphorylcholine and poly(D,L-lactic acid) containing copolymers as substrates for cell adhesion.
Artificial organs 2003;27(3):242-8.
2002: Kazuhiko Ishihara; Takashi Hasegawa; Junji Watanabe; Yasuhiko Iwasaki
Protein adsorption-resistant hollow fibers for blood purification.
Artificial organs 2002;26(12):1014-9.
2002: Junji Watanabe; Takahisa Eriguchi; Kazuhiko Ishihara
Cell adhesion and morphology in porous scaffold based on enantiomeric poly(lactic acid) graft-type phospholipid polymers.
Biomacromolecules 2002;3(6):1375-83.
2002: Ryo Ogawa; Yasuhiko Iwasaki; Kazuhiko Ishihara
Thermal property and processability of elastomeric polymer alloy composed of segmented polyurethane and phospholipid polymer.
Journal of biomedical materials research 2002;62(2):214-21.
2002: Junji Watanabe; Takahisa Eriguchi; Kazuhiko Ishihara
Stereocomplex formation by enantiomeric poly(lactic acid) graft-type phospholipid polymers for tissue engineering.
Biomacromolecules 2002;3(5):1109-14.
2002: Kwangwoo Nam; Junji Watanabe; Kazuhiko Ishihara
pH-modulated release of insulin entrapped in a spontaneously formed hydrogel system composed of two water-soluble phospholipid polymers.
Journal of biomaterials science. Polymer edition 2002;13(11):1259-69.
2002: Takashi Hasegawa; Yasuhiko Iwasaki; Kazuhiko Ishihara
Preparation of blood-compatible hollow fibers from a polymer alloy composed of polysulfone and 2-methacryloyloxyethyl phosphorylcholine polymer.
Journal of biomedical materials research 2002;63(3):333-41.
2002: Yoshihiro Kiritoshi; Kazuhiko Ishihara
Preparation of cross-linked biocompatible poly(2-methacryloyloxyethyl phosphorylcholine) gel and its strange swelling behavior in water/ethanol mixture.
Journal of biomaterials science. Polymer edition 2002;13(2):213-24.
2002: Kwangwoo Nam; Junji Watanabe; Kazuhiko Ishihara
Characterization of the spontaneously forming hydrogels composed of water-soluble phospholipid polymers.
Biomacromolecules 2002;3(1):100-5.
2001: Tomohiro Konno; K Kurita; Yasuhiko Iwasaki; Nobuo Nakabayashi; Kazuhiko Ishihara
Preparation of nanoparticles composed with bioinspired 2-methacryloyloxyethyl phosphorylcholine polymer.
Biomaterials 2001;22(13):1883-9.
2001: T Hasegawa; Yasuhiko Iwasaki; Kazuhiko Ishihara
Preparation and performance of protein-adsorption-resistant asymmetric porous membrane composed of polysulfone/phospholipid polymer blend.
Biomaterials 2001;22(3):243-51.
2001: Akinori Oki; S Adachi; Yuzuru Takamura; Kazuhiko Ishihara; Hideoki Ogawa; Y Ito; T Ichiki; Yasuhiro Horiike
Electroosmosis injection of blood serum into biocompatible microcapillary chip fabricated on quartz plate.
Electrophoresis 2001;22(2):341-7.
2000: Kazuhiko Ishihara; H Fujita; T Yoneyama; Yasuhiko Iwasaki
Antithrombogenic polymer alloy composed of 2-methacryloyloxyethyl phosphorylcholine polymer and segmented polyurethane.
Journal of biomaterials science. Polymer edition 2000;11(11):1183-95.
2000: Kazuhiko Ishihara
New polymeric biomaterials-phospholipid polymers with a biocompatible surface.
Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering 2000;10(2):83-95.
1999: Kazuhiko Ishihara; Kikuko Fukumoto; Yasuhiko Iwasaki; Nobuo Nakabayashi
Modification of polysulfone with phospholipid polymer for improvement of the blood compatibility. Part 2. Protein adsorption and platelet adhesion.
Biomaterials 1999;20(17):1553-9.
1999: Kazuhiko Ishihara; Kikuko Fukumoto; Yasuhiko Iwasaki; Nobuo Nakabayashi
Modification of polysulfone with phospholipid polymer for improvement of the blood compatibility. Part 1. Surface characterization.
Biomaterials 1999;20(17):1545-51.
1999: Kazuhiko Ishihara; E Ishikawa; Yasuhiko Iwasaki; Nobuo Nakabayashi
Inhibition of fibroblast cell adhesion on substrate by coating with 2-methacryloyloxyethyl phosphorylcholine polymers.
Journal of biomaterials science. Polymer edition 1999;10(10):1047-61.
1998: Kazuhiko Ishihara; Yasuhiko Iwasaki
Reduced protein adsorption on novel phospholipid polymers.
Journal of biomaterials applications 1998;13(2):111-27.