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Hiromichi Ishikawa

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Hiromichi Ishikawa; Keiji Tanaka; Y Maeda; Y Aiba; A Hata; Naotoshi Tsuji; Y Koga; T Matsumoto
Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells.
Masanobu Nanno; Yasuyoshi Kanari; Tomoaki Naito; Nagamu Inoue; Tadakazu Hisamatsu; Hiroshi Chinen; Ken Sugimoto; Yasuyo Shimomura; Hideo Yamagishi; Tetsuo Shiohara; Satoshi Ueha; Kouji Matsushima; Makoto Suematsu; Atsushi Mizoguchi; Toshifumi Hibi; Atul K Bhan; Hiromichi Ishikawa
Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.
Hiromichi Ishikawa; Tomoaki Naito; Toshihiko Iwanaga; Hiromi Takahashi-Iwanaga; Makoto Suematsu; Toshifumi Hibi; Masanobu Nanno
Curriculum vitae of intestinal intraepithelial T cells: their developmental and behavioral characteristics.

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All Publications

2008: Hiromichi Ishikawa; Keiji Tanaka; Y Maeda; Y Aiba; A Hata; Naotoshi Tsuji; Y Koga; T Matsumoto
Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells.
Clinical and experimental immunology 2008;153(1):127-35.
2008: Masanobu Nanno; Yasuyoshi Kanari; Tomoaki Naito; Nagamu Inoue; Tadakazu Hisamatsu; Hiroshi Chinen; Ken Sugimoto; Yasuyo Shimomura; Hideo Yamagishi; Tetsuo Shiohara; Satoshi Ueha; Kouji Matsushima; Makoto Suematsu; Atsushi Mizoguchi; Toshifumi Hibi; Atul K Bhan; Hiromichi Ishikawa
Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.
Gastroenterology 2008;134(2):481-90.
2007: Hiromichi Ishikawa; Tomoaki Naito; Toshihiko Iwanaga; Hiromi Takahashi-Iwanaga; Makoto Suematsu; Toshifumi Hibi; Masanobu Nanno
Curriculum vitae of intestinal intraepithelial T cells: their developmental and behavioral characteristics.
Immunological reviews 2007;215():154-65.
2007: Masanobu Nanno; Tetsuo Shiohara; Hiroshi Yamamoto; Kazuyoshi Kawakami; Hiromichi Ishikawa
gammadelta T cells: firefighters or fire boosters in the front lines of inflammatory responses.
Immunological reviews 2007;215():103-13.
2006: Neelanjan Ray; Masayoshi Kuwahara; Yasunari Takada; Kenta Maruyama; Tomohiro Kawaguchi; Hirokazu Tsubone; Hiromichi Ishikawa; Koichi Matsuo
c-Fos suppresses systemic inflammatory response to endotoxin.
International immunology 2006;18(5):671-7.
2005: Osamu Hitotsumatsu; Hiromasa Hamada; Makoto Naganuma; Nagamu Inoue; Hiromasa Ishii; Toshifumi Hibi; Hiromichi Ishikawa
Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.
Journal of gastroenterology 2005;40(10):956-63.
2005: Masanobu Nanno; Hiromichi Ishikawa
[Physiological function of intestinal intraepithelial gamma-delta T lymphocytes].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():454-8.
2005: Satoshi Nonaka; Tomoaki Naito; Hao Chen; Masafumi Yamamoto; Kazuyo Moro; Hiroshi Kiyono; Hiromasa Hamada; Hiromichi Ishikawa
Intestinal gamma delta T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):1906-12.
2004: Koichi Matsuo; Deborah L Galson; Chen Zhao; Lan Peng; Catherine Laplace; Kent Z Q Wang; Marcus A Bachler; Hitoshi Amano; Hiroyuki Aburatani; Hiromichi Ishikawa; Erwin F Wagner
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.
The Journal of biological chemistry 2004;279(25):26475-80.
2003: Ryoichi Iiyama; Takanori Kanai; Koji Uraushihara; Takahiro Ishikura; Shin Makita; Teruji Totsuka; Motomi Yamazaki; Tetsuya Nakamura; Tatsuya Miyata; Hideo Yoshida; O Takeuchi; K Hoshino; Kiyoshi Takeda; Hiromichi Ishikawa; Shizuo Akira; Masahiko Watanabe
Normal development of the gut-associated lymphoid tissue except Peyer's patch in MyD88-deficient mice.
Scandinavian journal of immunology 2003;58(6):620-7.
2003: Shin Makita; Takanori Kanai; S Matsumoto; Ryoichi Iiyama; Koji Uraushihara; Teruji Totsuka; Motomi Yamazaki; Tetsuya Nakamura; Hiromichi Ishikawa; Masahiko Watanabe
The role of cryptopatch-derived intraepithelial lymphocytes in the development of chronic ileocecitis.
Scandinavian journal of immunology 2003;58(4):428-35.
2003: Motomi Yamazaki; Tomoharu Yajima; Masanobu Tanabe; Kazuto Fukui; Eriko Okada; Ryuichi Okamoto; Shigeru Oshima; Tetsuya Nakamura; Takanori Kanai; Masahiro Uehira; Tsutomu Takeuchi; Hiromichi Ishikawa; Toshifumi Hibi; Mamoru Watanabe
Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1556-63.
2003: Masao Goto; Satoshi Hachimura; Akio Ametani; Takehito Sato; Yoshihiro Kumagai; Sonoko Habu; Mamoru Totsuka; Hiromichi Ishikawa; Shuichi Kaminogawa
Antigen feeding increases frequency and antigen-specific proliferation ability of intraepithelial CD4+ T cells in alphabeta T cell receptor transgenic mice.
Bioscience, biotechnology, and biochemistry 2003;67(6):1223-9.
2003: Masako Murai; Hiroyuki Yoneyama; Taichi Ezaki; Makoto Suematsu; Yuya Terashima; Akihisa Harada; Hiromasa Hamada; Hitoshi Asakura; Hiromichi Ishikawa; Kouji Matsushima
Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction.
Nature immunology 2003;4(2):154-60.
2002: Nobuyuki Onai; Masahiro Kitabatake; Yan-yun Zhang; Hiromichi Ishikawa; Sho Ishikawa; Kouji Matsushima
Pivotal role of CCL25 (TECK)-CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes.
International immunology 2002;14(7):687-94.
2002: Yasuhiro Nishiyama; Hiromasa Hamada; Satoshi Nonaka; Hiroshi Yamamoto; Masanobu Nanno; Yasuo Katayama; Hidemi Takahashi; Hiromichi Ishikawa
Homeostatic regulation of intestinal villous epithelia by B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2626-33.
2002: Hiromasa Hamada; Takachika Hiroi; Yasuhiro Nishiyama; Hidemi Takahashi; Yohei Masunaga; Satoshi Hachimura; Shuichi Kaminogawa; Hiromi Takahashi-Iwanaga; Toshihiko Iwanaga; Hiroshi Kiyono; Hiroshi Yamamoto; Hiromichi Ishikawa
Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):57-64.
2001: M Kawaguchi-Miyashita; Shin-ichiro Shimada; H Kurosu; N Kato-Nagaoka; Yoshiaki Matsuoka; Makoto Ohwaki; Hiromichi Ishikawa; Masanobu Nanno
An accessory role of TCRgammadelta (+) cells in the exacerbation of inflammatory bowel disease in TCRalpha mutant mice.
European journal of immunology 2001;31(4):980-8.
2000: K Suzuki; Takatoku Oida; Hiromasa Hamada; O Hitotsumatsu; Masahiko Watanabe; Toshifumi Hibi; Hiroshi Yamamoto; E Kubota; Shuichi Kaminogawa; Hiromichi Ishikawa
Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis.
Immunity 2000;13(5):691-702.
2000: Takatoku Oida; K Suzuki; Masanobu Nanno; Y Kanamori; H Saito; E Kubota; S Kato; M Itoh; Shuichi Kaminogawa; Hiromichi Ishikawa
Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3616-26.
1999: Masako Kohyama; Masanobu Nanno; M Kawaguchi-Miyashita; Shin-ichiro Shimada; Masahiko Watanabe; Toshifumi Hibi; Shuichi Kaminogawa; Hiromichi Ishikawa
Cytolytic and IFN-gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are T cell receptor-beta-chain dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7451-5.
1999: Hiromichi Ishikawa; H Saito; K Suzuki; Takatoku Oida; Y Kanamori
New gut associated lymphoid tissue "cryptopatches" breed murine intestinal intraepithelial T cell precursors.
Immunologic research 1999;20(3):243-50.
1998: Masanobu Nanno; Y Kanamori; H Saito; M Kawaguchi-Miyashita; Shin-ichiro Shimada; Hiromichi Ishikawa
Intestinal intraepithelial T lymphocytes. Our T cell horizons are expanding.
Immunologic research 1998;18(1):41-53.
1998: H Saito; Y Kanamori; T Takemori; H Nariuchi; E Kubota; Hiromi Takahashi-Iwanaga; Toshihiko Iwanaga; Hiromichi Ishikawa
Generation of intestinal T cells from progenitors residing in gut cryptopatches.
Science (New York, N.Y.) 1998;280(5361):275-8.
1998: Masahiko Watanabe; Y Ueno; Tomoharu Yajima; Susumu Okamoto; T Hayashi; Motomi Yamazaki; Yasushi Iwao; Hiromasa Ishii; S Habu; Masahiro Uehira; H Nishimoto; Hiromichi Ishikawa; J Hata; Toshifumi Hibi
Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa.
The Journal of experimental medicine 1998;187(3):389-402.
1997: Masako Kohyama; Satoshi Hachimura; Masanobu Nanno; Hiromichi Ishikawa; Shuichi Kaminogawa
Analysis of cytokine producing activity of intestinal intraepithelial T cells from TCR beta-chain and delta-chain mutant mice.
Microbiology and immunology 1997;41(4):353-9.
1996: M Kawaguchi-Miyashita; K Shimizu; Masanobu Nanno; Shin-ichiro Shimada; T Watanabe; Y Koga; Yoshiaki Matsuoka; Hiromichi Ishikawa; K Hashimoto; Makoto Ohwaki
Development and cytolytic function of intestinal intraepithelial T lymphocytes in antigen-minimized mice.
Immunology 1996;89(2):268-73.
1996: Y Kanamori; K Ishimaru; Masanobu Nanno; K Maki; K Ikuta; H Nariuchi; Hiromichi Ishikawa
Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop.
The Journal of experimental medicine 1996;184(4):1449-59.
1996: Y Fujiura; M Kawaguchi; Y Kondo; S Obana; H Yamamoto; Masanobu Nanno; Hiromichi Ishikawa
Development of CD8 alpha alpha+ intestinal intraepithelial T cells in beta 2-microglobulin- and/or TAP1-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2710-5.
1993: M Kawaguchi; Masanobu Nanno; Yoshinori Umesaki; S Matsumoto; Y Okada; Z Cai; T Shimamura; Yoshiaki Matsuoka; Makoto Ohwaki; Hiromichi Ishikawa
Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8591-4.
1993: Hiromichi Ishikawa; J Hayakawa; Tetsuo Shiohara
Cytotoxic T cell responses to minor H-43 alloantigens in H-43a and H-43b mice. Distinctive MHC class I restriction specificity and clonal inactivation are inherent properties of the H-43 system.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(5):2436-43.
1989: Hiromichi Ishikawa; K Saito; E Kubota
Modulation of F1 cytotoxic potentials by graft-vs-host reaction. Cooperative non-H-2- and H-2D region-gene control of F1 natural resistance to graft-vs-host reaction-associated immunosuppression.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1495-9.
1988: Hiromichi Ishikawa; A Kusakabe; J Hayakawa; T Hino
Cytotoxic T lymphocyte responses to minor H-43 alloantigens in H-43a and H-43b mice. Both anti-H-43b and anti-H-43a CTL activities are generated exclusively in the context of the same H-2Kb restriction element.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):2918-23.
1988: H Suzuki; Hiromichi Ishikawa; T Hino; H Kato; A Kusakabe; K Saito
Effector mechanism in rejection of allografts expressing an isolated minor histocompatibility disparity. Importance of cytotoxic T lymphocytes in the rejection of H-43a allografts by H-43b mice.
Transplantation 1988;45(2):459-64.
1988: T Hino; Hiromichi Ishikawa; K Saito
Cytotoxic T lymphocyte response to minor H-43a alloantigen in H-43b mice. Privileged H-2Kb restriction to the response is not due to immunodominance or epistatic effect but due to Ir gene function of H-2Kb itself.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(1):44-51.
1987: Hiromichi Ishikawa; T Hino; H Kato; H Suzuki; K Saito
Cytotoxic T-lymphocyte tolerance to minor H-43a alloantigen is induced exclusively in the context of the self major histocompatibility complex class I H-2Kb molecules.
Cellular immunology 1987;110(2):436-42.