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Yogesh Awasthi

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Chemicals & Drugs

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Archana Sehrawat; Charles Warden; Sushma Yadav; Yogesh C Awasthi; Alakananda Basu; Sanjay Awasthi
P300 regulates the human RLIP76 promoter activity and gene expression.
Rajendra Sharma; Sanjay Awasthi; Pankaj Chaudhary; Shailesh Jaiswal; Mukesh Sahu; Abha Sharma; Yogesh C Awasthi
Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane.
Rit Vatsyayan; Sanjay Awasthi; Pankaj Chaudhary; Sushil Kumar; Poorna Chandra Rao Lelsani; Yogesh C Awasthi
The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4.

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All Publications

2013: Archana Sehrawat; Charles Warden; Sushma Yadav; Yogesh C Awasthi; Alakananda Basu; Sanjay Awasthi
P300 regulates the human RLIP76 promoter activity and gene expression.
Biochemical pharmacology 2013;85(8):1203-11.
2012: Rajendra Sharma; Sanjay Awasthi; Pankaj Chaudhary; Shailesh Jaiswal; Mukesh Sahu; Abha Sharma; Yogesh C Awasthi
Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane.
Free radical biology & medicine 2012;52(11-12):2177-85.
2012: Rit Vatsyayan; Sanjay Awasthi; Pankaj Chaudhary; Sushil Kumar; Poorna Chandra Rao Lelsani; Yogesh C Awasthi
The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4.
Biochemical and biophysical research communications 2012;417(1):346-51.
2011: Sushil Kumar; Mukesh Sahu; Rajendra Sharma; Sanjay Awasthi; Pankaj Chaudhary; Rutika A Kokate; Yogesh C Awasthi
Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human cancer xenografts in nude mice.
Indian journal of experimental biology 2011;49(11):817-25.
2011: Rit Vatsyayan; Pankaj Chaudhary; Abha Sharma; Rajendra Sharma; Poorna Chandra Rao Lelsani; Sanjay Awasthi; Yogesh C Awasthi
Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells.
Experimental eye research 2011;92(2):147-54.
2011: Sharad S Singhal; Dilki Wickramarachchi; Sushma Yadav; Jyotsana Singhal; Kathryn Leake; Rit Vatsyayan; Pankaj Chaudhary; Poorna Lelsani; Sumihiro Suzuki; Shaohua Yang; Yogesh C Awasthi; Sanjay Awasthi
Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis.
Molecular cancer therapeutics 2011;10(1):16-28.
2010: Erika L Abel; Joe M Angel; Penny K Riggs; Laura Langfield; Herng-Hsiang Lo; Maria D Person; Yogesh C Awasthi; Li-E Wang; Sara S Strom; Qingyi Wei; John DiGiovanni
Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.
Journal of the National Cancer Institute 2010;102(21):1663-75.
2010: Pankaj Chaudhary; Rajendra Sharma; Abha Sharma; Rit Vatsyayan; Sushma Yadav; shashank singhal; Navin Rauniyar; Laszlo Prokai; Sanjay Awasthi; Yogesh C Awasthi
Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling.
Biochemistry 2010;49(29):6263-75.
2010: Rajendra Sharma; Abha Sharma; Pankaj Chaudhary; Virginia Pearce; Rit Vatsyayan; Shivendra V Singh; Sanjay Awasthi; Yogesh C Awasthi
Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent.
Biochemistry 2010;49(14):3191-202.
2010: Sanjay Awasthi; shashank singhal; Sushma Yadav; Jyotsana Singhal; Rit Vatsyayan; Ewa Zajac; Rafal Luchowski; Jozef Borvak; Karol Gryczynski; Yogesh C Awasthi
A central role of RLIP76 in regulation of glycemic control.
Diabetes 2010;59(3):714-25.
2010: Ya Xu; Bin Gong; Yongzhen Yang; Yogesh C Awasthi; Paul J Boor
Adenovirus-mediated overexpression of glutathione-s-transferase mitigates transplant arteriosclerosis in rabbit carotid allografts.
Transplantation 2010;89(4):409-16.
2009: Yogesh C Awasthi; Pankaj Chaudhary; Rit Vatsyayan; Abha Sharma; Sanjay Awasthi; Rajendra Sharma
Physiological and pharmacological significance of glutathione-conjugate transport.
Journal of toxicology and environmental health. Part B, Critical reviews 2009;12(7):540-51.
2009: Rit Vatsyayan; Pankaj Chaudhary; Poorna Chandra Rao Lelsani; Preeti Singhal; Yogesh C Awasthi; Sanjay Awasthi; shashank singhal
Role of RLIP76 in doxorubicin resistance in lung cancer.
International journal of oncology 2009;34(6):1505-11.
2009: shashank singhal; Jyotsana Singhal; Sushma Yadav; Mukesh Sahu; Yogesh C Awasthi; Sanjay Awasthi
RLIP76: a target for kidney cancer therapy.
Cancer research 2009;69(10):4244-51.
2008: Abha Sharma; Rajendra Sharma; Pankaj Chaudhary; Rit Vatsyayan; Virginia Pearce; Prince V S Jeyabal; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells.
Archives of biochemistry and biophysics 2008;480(2):85-94.
2008: Jyotsana Singhal; shashank singhal; Sushma Yadav; Sumihiro Suzuki; Molly M Warnke; Adly Yacoub; Paul Dent; Sejong Bae; Rajendra Sharma; Yogesh C Awasthi; Daniel W Armstrong; Sanjay Awasthi
RLIP76 in defense of radiation poisoning.
International journal of radiation oncology, biology, physics 2008;72(2):553-61.
2008: Sanjay Awasthi; shashank singhal; Yogesh C Awasthi; Bryan Martin; Jung-Hee Woo; C Casey Cunningham; Arthur E Frankel
RLIP76 and Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4372-7.
2008: Yusong Yang; Yusong Yang; Ya Xu; Scott D Lick; Yogesh C Awasthi; Paul J Boor
Endothelial glutathione-S-transferase A4-4 protects against oxidative stress and modulates iNOS expression through NF-kappaB translocation.
Toxicology and applied pharmacology 2008;230(2):187-96.
2008: Yogesh C Awasthi; Rajendra Sharma; Abha Sharma; Sushma Yadav; shashank singhal; Pankaj Chaudhary; Sanjay Awasthi
Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.
Free radical biology & medicine 2008;45(2):111-8.
2008: Sharda P Singh; Maciej Niemczyk; Deepti Saini; Yogesh C Awasthi; Ludwika Zimniak; Piotr Zimniak
Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice.
Biochemistry 2008;47(12):3900-11.
2008: Umesh C S Yadav; Kota V Ramana; Yogesh C Awasthi; Satish K Srivastava
Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells.
Toxicology and applied pharmacology 2008;227(2):257-64.
2008: Rajendra Sharma; Abha Sharma; Seema Dwivedi; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
Biochemistry 2008;47(1):143-56.
2007: Damir Janigro; Sanjay Awasthi; Yogesh C Awasthi; Rajendra Sharma; Sushma Yadav; shashank singhal; Kerri Hallene
RLIP76 in AED drug resistance.
Epilepsia 2007;48(6):1218-9; author reply 1219-20.
2007: Yogesh C Awasthi; Rajendra Sharma; Sushma Yadav; Seema Dwivedi; Abha Sharma; Sanjay Awasthi
The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance.
Current drug metabolism 2007;8(4):315-23.
2007: shashank singhal; Jyotsana Singhal; Sushma Yadav; Seema Dwivedi; Paul J Boor; Yogesh C Awasthi; Sanjay Awasthi
Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1).
Cancer research 2007;67(9):4382-9.
2007: shashank singhal; Jyotsana Singhal; Maya P Nair; Andras G Lacko; Yogesh C Awasthi; Sanjay Awasthi
Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer.
International journal of oncology 2007;30(3):717-25.
2007: Seema Dwivedi; Abha Sharma; Brad Patrick; Rajendra Sharma; Yogesh C Awasthi
Role of 4-hydroxynonenal and its metabolites in signaling.
Redox report : communications in free radical research 2007;12(1):4-10.
2006: Jie Li; Rajendra Sharma; Brad Patrick; Abha Sharma; Prince V S Jeyabal; Prasada M R V Reddy; Manjit K Saini; Seema Dwivedi; Shaheen Dhanani; Naseem H Ansari; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal.
Biochemistry 2006;45(40):12253-64.
2006: shashank singhal; Sushma Yadav; Jyotsana Singhal; Yogesh C Awasthi; Sanjay Awasthi
Mitogenic and drug-resistance mediating effects of PKCalpha require RLIP76.
Biochemical and biophysical research communications 2006;348(2):722-7.
2006: Abha Sharma; Brad Patrick; Jie Li; Rajendra Sharma; Prince V S Jeyabal; Prasada M R V Reddy; Sanjay Awasthi; Yogesh C Awasthi
Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis.
Archives of biochemistry and biophysics 2006;452(2):165-73.
2006: Kota V Ramana; Aruni Bhatnagar; Sanjay Srivastava; Umesh C S Yadav; Sanjay Awasthi; Yogesh C Awasthi; Satish K Srivastava
Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth.
The Journal of biological chemistry 2006;281(26):17652-60.
2006: shashank singhal; Dilki Wickramarachchi; Jyotsana Singhal; Sushma Yadav; Yogesh C Awasthi; Sanjay Awasthi
Determinants of differential doxorubicin sensitivity between SCLC and NSCLC.
FEBS letters 2006;580(9):2258-64.
2006: shashank singhal; Yogesh C Awasthi; Sanjay Awasthi
Regression of melanoma in a murine model by RLIP76 depletion.
Cancer research 2006;66(4):2354-60.
2006: Seema Dwivedi; Rajendra Sharma; Abha Sharma; Piotr Zimniak; Jeffrey D Ceci; Yogesh C Awasthi; Paul J Boor
The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice.
Toxicology 2006;218(1):58-66.
2005: shashank singhal; Sushma Yadav; Jyotsana Singhal; Kenneth Drake; Yogesh C Awasthi; Sanjay Awasthi
The role of PKCalpha and RLIP76 in transport-mediated doxorubicin-resistance in lung cancer.
FEBS letters 2005;579(21):4635-41.
2005: Brad Patrick; Jie Li; Prince V S Jeyabal; Prasada M R V Reddy; Yusong Yang; Rajendra Sharma; Mala Sinha; Bruce A Luxon; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression.
Biochemical and biophysical research communications 2005;334(2):425-32.
2005: John S Hurst; Manjit K Saini; Gui-Fang Jin; Yogesh C Awasthi; Frederik J G M van Kuijk
Toxicity of oxidized beta-carotene to cultured human cells.
Experimental eye research 2005;81(2):239-43.
2005: shashank singhal; Sushma Yadav; Jyotsana Singhal; Ewa Zajac; Yogesh C Awasthi; Sanjay Awasthi
Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin.
Biochemical pharmacology 2005;70(3):481-8.
2005: Sanjay Awasthi; shashank singhal; Sushma Yadav; Jyotsana Singhal; Kenneth Drake; Aalok Nadkar; Ewa Zajac; Dilki Wickramarachchi; Nancy Rowe; Adly Yacoub; Paul Boor; Seema Dwivedi; Paul Dent; Wendy E Jarman; Berchmans John; Yogesh C Awasthi
RLIP76 is a major determinant of radiation sensitivity.
Cancer research 2005;65(14):6022-8.
2005: Sushma Yadav; Ewa Zajac; shashank singhal; Jyotsana Singhal; Kenneth Drake; Yogesh C Awasthi; Sanjay Awasthi
POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis.
Biochemical and biophysical research communications 2005;328(4):1003-9.
2005: David Stuckler; Jyotsana Singhal; shashank singhal; Sushma Yadav; Yogesh C Awasthi; Sanjay Awasthi
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer.
Cancer research 2005;65(3):991-8.
2005: Yogesh C Awasthi; G A S Ansari; Sanjay Awasthi
Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases.
Methods in enzymology 2005;401():379-407.
2005: Sanjay Awasthi; Kerri Hallene; Vincent Fazio; shashank singhal; Luca Cucullo; Yogesh C Awasthi; Gabriele Dini; Damir Janigro
RLIP76, a non-ABC transporter, and drug resistance in epilepsy.
BMC neuroscience 2005;6():61.
2005: Fong-Qi Liang; Rajiha Alssadi; Preston Morehead; Yogesh C Awasthi; Bernard F Godley
Enhanced expression of glutathione-S-transferase A1-1 protects against oxidative stress in human retinal pigment epithelial cells.
Experimental eye research 2005;80(1):113-9.
2004: Sushma Yadav; shashank singhal; Jyotsana Singhal; Dilki Wickramarachchi; Eugene Knutson; Thomas B Albrecht; Yogesh C Awasthi; Sanjay Awasthi
Identification of membrane-anchoring domains of RLIP76 using deletion mutant analyses.
Biochemistry 2004;43(51):16243-53.
2004: Rajendra Sharma; shashank singhal; Dilki Wickramarachchi; Yogesh C Awasthi; Sanjay Awasthi
RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistance.
International journal of cancer. Journal international du cancer 2004;112(6):934-42.
2004: Yogesh C Awasthi; Yusong Yang; Narendra K Tiwari; Brad Patrick; Abha Sharma; Jie Li; Sanjay Awasthi
Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases.
Free radical biology & medicine 2004;37(5):607-19.
2004: Rajendra Sharma; David Brown; Sanjay Awasthi; Yusong Yang; Abha Sharma; Brad Patrick; Manjit K Saini; Sharda P Singh; Piotr Zimniak; Shivendra V Singh; Yogesh C Awasthi
Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells.
European journal of biochemistry / FEBS 2004;271(9):1690-701.
2004: Yusong Yang; Yusong Yang; Margaret B Trent; Nonggao He; Scott D Lick; Piotr Zimniak; Yogesh C Awasthi; Paul J Boor
Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis.
Atherosclerosis 2004;173(2):211-21.
2004: Rajendra Sharma; Yusong Yang; Abha Sharma; Sanjay Awasthi; Yogesh C Awasthi
Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis.
Antioxidants & redox signaling 2004;6(2):289-300.
2004: Mark R Engle; Sharda P Singh; Piotr J Czernik; Dana Gaddy; Donna C Montague; Jeffrey D Ceci; Yusong Yang; Sanjay Awasthi; Yogesh C Awasthi; Piotr Zimniak
Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse.
Toxicology and applied pharmacology 2004;194(3):296-308.
2003: Yusong Yang; Abha Sharma; Rajendra Sharma; Brad Patrick; shashank singhal; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis.
The Journal of biological chemistry 2003;278(42):41380-8.
2003: Sanjay Awasthi; shashank singhal; Rajendra Sharma; Piotr Zimniak; Yogesh C Awasthi
Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistance.
International journal of cancer. Journal international du cancer 2003;106(5):635-46.
2003: Yogesh C Awasthi; Rajendra Sharma; Ji-Zhong Cheng; Yusong Yang; Abha Sharma; shashank singhal; Sanjay Awasthi
Role of 4-hydroxynonenal in stress-mediated apoptosis signaling.
Molecular aspects of medicine 2003;24(4-5):219-30.
2003: Rajendra Sharma; Yusong Yang; Abha Sharma; Seema Dwivedi; Vsevolod L Popov; Paul J Boor; shashank singhal; Sanjay Awasthi; Yogesh C Awasthi
Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells.
Investigative ophthalmology & visual science 2003;44(8):3438-49.
2003: Rajendra Sharma; Yogesh C Awasthi; Yusong Yang; Abha Sharma; shashank singhal; Sanjay Awasthi
Energy dependent transport of xenobiotics and its relevance to multidrug resistance.
Current cancer drug targets 2003;3(2):89-107.
2003: Sanjay Awasthi; shashank singhal; Jyotsana Singhal; Yusong Yang; Piotr Zimniak; Yogesh C Awasthi
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity.
International journal of oncology 2003;22(4):721-32.
2003: Sanjay Awasthi; shashank singhal; Jyotsana Singhal; Jizhong Cheng; Piotr Zimniak; Yogesh C Awasthi
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76.
International journal of oncology 2003;22(4):713-20.
2003: shashank singhal; Jyotsana Singhal; Rajendra Sharma; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi; Sanjay Awasthi
Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.
International journal of oncology 2003;22(2):365-75.
2003: Yusong Yang; Rajendra Sharma; Abha Sharma; Sanjay Awasthi; Yogesh C Awasthi
Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling.
Acta biochimica Polonica 2003;50(2):319-36.
2002: Sanjay Awasthi; Rajendra Sharma; shashank singhal; Piotr Zimniak; Yogesh C Awasthi
RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(12):1300-10.
2002: Yusong Yang; Rajendra Sharma; Piotr Zimniak; Yogesh C Awasthi
Role of alpha class glutathione S-transferases as antioxidant enzymes in rodent tissues.
Toxicology and applied pharmacology 2002;182(2):105-15.
2002: Sharda P Singh; Andrzej J Janecki; Satish K Srivastava; Sanjay Awasthi; Yogesh C Awasthi; Shujuan J Xia; Piotr Zimniak
Membrane association of glutathione S-transferase mGSTA4-4, an enzyme that metabolizes lipid peroxidation products.
The Journal of biological chemistry 2002;277(6):4232-9.
2002: Yusong Yang; Rajendra Sharma; Ji-Zhong Cheng; Manjit K Saini; Naseem H Ansari; Usha P Andley; Sanjay Awasthi; Yogesh C Awasthi
Protection of HLE B-3 cells against hydrogen peroxide- and naphthalene-induced lipid peroxidation and apoptosis by transfection with hGSTA1 and hGSTA2.
Investigative ophthalmology & visual science 2002;43(2):434-45.
2002: Sanjay Awasthi; Rajendra Sharma; Yusong Yang; shashank singhal; Slawomir Pikula; Joanna Bandorowicz-Pikula; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi
Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76).
Acta biochimica Polonica 2002;49(4):855-67.
2002: Rajendra Sharma; Abha Sharma; Yusong Yang; Sanjay Awasthi; shashank singhal; Piotr Zimniak; Yogesh C Awasthi
Functional reconstitution of Ral-binding GTPase activating protein, RLIP76, in proteoliposomes catalyzing ATP-dependent transport of glutathione conjugate of 4-hydroxynonenal.
Acta biochimica Polonica 2002;49(3):693-701.
2001: Ji-Zhong Cheng; Rajendra Sharma; Yusong Yang; shashank singhal; Abha Sharma; Manjit K Saini; Shivendra V Singh; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress.
The Journal of biological chemistry 2001;276(44):41213-23.
2001: Ji-Zhong Cheng; shashank singhal; Abha Sharma; Manjit K Saini; Yusong Yang; Sanjay Awasthi; Piotr Zimniak; Yogesh C Awasthi
Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling.
Archives of biochemistry and biophysics 2001;392(2):197-207.
2001: Rajendra Sharma; shashank singhal; Jizhong Cheng; Yusong Yang; Abha Sharma; Piotr Zimniak; Sanjay Awasthi; Yogesh C Awasthi
RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes.
Archives of biochemistry and biophysics 2001;391(2):171-9.
2001: Yusong Yang; Ji-Zhong Cheng; shashank singhal; Manjit K Saini; Utpal Pandya; Sanjay Awasthi; Yogesh C Awasthi
Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation.
The Journal of biological chemistry 2001;276(22):19220-30.
2001: Ji-Zhong Cheng; Yusong Yang; S P Singh; shashank singhal; Sanjay Awasthi; Su-Shu Pan; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi
Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues.
Biochemical and biophysical research communications 2001;282(5):1268-74.
2001: Sanjay Awasthi; Ji-Zhong Cheng; shashank singhal; Utpal Pandya; Rajendra Sharma; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi
Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.
Biochemistry 2001;40(13):4159-68.
2001: shashank singhal; Jyotsana Singhal; Jizhong Cheng; S Pikuła; Rajendra Sharma; Piotr Zimniak; Yogesh C Awasthi; Sanjay Awasthi
Purification and functional reconstitution of intact ral-binding Gtpase activating protein, RLIP76, in artificial liposomes.
Acta biochimica Polonica 2001;48(2):551-62.
2000: Utpal Pandya; Sanjay Srivastava; shashank singhal; A Pal; Sanjay Awasthi; Piotr Zimniak; Yogesh C Awasthi; Shivendra V Singh
Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.
Biochemical and biophysical research communications 2000;278(1):258-62.
2000: Sanjay Awasthi; Utpal Pandya; shashank singhal; J T Lin; V Thiviyanathan; W E Seifert; Yogesh C Awasthi; G A Ansari
Curcumin-glutathione interactions and the role of human glutathione S-transferase P1-1.
Chemico-biological interactions 2000;128(1):19-38.
2000: Sanjay Awasthi; Jizhong Cheng; shashank singhal; Manjit K Saini; Utpal Pandya; Slawomir Pikula; Joanna Bandorowicz-Pikula; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi
Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin.
Biochemistry 2000;39(31):9327-34.
2000: Utpal Pandya; Manjit K Saini; Gui-Fang Jin; Sanjay Awasthi; Bernard F Godley; Yogesh C Awasthi
Dietary curcumin prevents ocular toxicity of naphthalene in rats.
Toxicology letters 2000;115(3):195-204.
2000: Rajendra Sharma; Sanjay Awasthi; Piotr Zimniak; Yogesh C Awasthi
Transport of glutathione-conjugates in human erythrocytes.
Acta biochimica Polonica 2000;47(3):751-62.
1999: Ji-Zhong Cheng; shashank singhal; Manjit K Saini; Jyotsana Singhal; JT Piper; Frederik J G M van Kuijk; Piotr Zimniak; Yogesh C Awasthi; Sanjay Awasthi
Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells.
Archives of biochemistry and biophysics 1999;372(1):29-36.
1999: shashank singhal; Bernard F Godley; A Chandra; Utpal Pandya; Gui-Fang Jin; Manjit K Saini; Sanjay Awasthi; Yogesh C Awasthi
Induction of glutathione S-transferase hGST 5.8 is an early response to oxidative stress in RPE cells.
Investigative ophthalmology & visual science 1999;40(11):2652-9.
1999: shashank singhal; Sanjay Awasthi; Utpal Pandya; JT Piper; Manjit K Saini; Ji-Zhong Cheng; Yogesh C Awasthi
The effect of curcumin on glutathione-linked enzymes in K562 human leukemia cells.
Toxicology letters 1999;109(1-2):87-95.
1999: Julie K Horton; G Roy; JT Piper; Bennett Van Houten; Yogesh C Awasthi; S Mitra; M A Alaoui-Jamali; Istvan Boldogh; shashank singhal
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
Biochemical pharmacology 1999;58(4):693-702.
1999: T Zhao; shashank singhal; JT Piper; Jizhong Cheng; Utpal Pandya; J Clark-Wronski; Sanjay Awasthi; Yogesh C Awasthi
The role of human glutathione S-transferases hGSTA1-1 and hGSTA2-2 in protection against oxidative stress.
Archives of biochemistry and biophysics 1999;367(2):216-24.
1999: Piotr Zimniak; Slawomir Pikula; Joanna Bandorowicz-Pikula; Yogesh C Awasthi
Mechanisms for xenobiotic transport in biological membranes.
Toxicology letters 1999;106(2-3):107-18.
1999: Sanjay Awasthi; shashank singhal; Utpal Pandya; S Gopal; Piotr Zimniak; Shivendra V Singh; Yogesh C Awasthi
ATP-Dependent colchicine transport by human erythrocyte glutathione conjugate transporter.
Toxicology and applied pharmacology 1999;155(3):215-26.
1998: Sanjay Awasthi; shashank singhal; Slawomir Pikula; JT Piper; Satish K Srivastava; RT Torman; Joanna Bandorowicz-Pikula; J T Lin; Shivendra V Singh; Piotr Zimniak; Yogesh C Awasthi
ATP-Dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activity.
Biochemistry 1998;37(15):5239-48.
1998: Sanjay Awasthi; shashank singhal; Satish K Srivastava; RT Torman; Piotr Zimniak; Joanna Bandorowicz-Pikula; Shivendra V Singh; JT Piper; Yogesh C Awasthi; Slawomir Pikula
ATP-Dependent human erythrocyte glutathione-conjugate transporter. I. Purification, photoaffinity labeling, and kinetic characteristics of ATPase activity.
Biochemistry 1998;37(15):5231-8.
1998: JT Piper; shashank singhal; M S Salameh; RT Torman; Yogesh C Awasthi; Sanjay Awasthi
Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver.
The international journal of biochemistry & cell biology 1998;30(4):445-56.
1997: R Sharma; Abida K Haque; Sanjay Awasthi; Shivendra V Singh; JT Piper; Yogesh C Awasthi
Differential carcinogenicity of benzo[a]pyrene in male and female CD-1 mouse lung.
Journal of toxicology and environmental health 1997;52(1):45-62.
1997: Sanjay Awasthi; shashank singhal; Satish K Srivastava; M Chaubey; JT Piper; Piotr Zimniak; Chandra Yallampalli; Srinivasan Rajaraman; Yogesh C Awasthi
Rat GST 8-8 is expressed predominantly in myeloid origin cells infiltrating the gravid uterus.
The international journal of biochemistry & cell biology 1997;29(5):807-13.