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Koichi Isowa

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TOP 3
Yasuko Obata; Yuriko Ashitaka; Shingo Kikuchi; Koichi Isowa; Kozo Takayama
A statistical approach to the development of a transdermal delivery system for ondansetron.
El-Sayed Khafagy; Mariko Morishita; Nobuo Ida; Reiji Nishio; Koichi Isowa; Kozo Takayama
Structural requirements of penetratin absorption enhancement efficiency for insulin delivery.
Masato Nishikawa; Yoshinori Onuki; Koichi Isowa; Kozo Takayama
Formulation optimization of an indomethacin-containing photocrosslinked polyacrylic acid hydrogel as an anti-inflammatory patch.

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All Publications

2010: Yasuko Obata; Yuriko Ashitaka; Shingo Kikuchi; Koichi Isowa; Kozo Takayama
A statistical approach to the development of a transdermal delivery system for ondansetron.
International journal of pharmaceutics 2010;399(1-2):87-93.
2010: El-Sayed Khafagy; Mariko Morishita; Nobuo Ida; Reiji Nishio; Koichi Isowa; Kozo Takayama
Structural requirements of penetratin absorption enhancement efficiency for insulin delivery.
Journal of controlled release : official journal of the Controlled Release Society 2010;143(3):302-10.
2008: Masato Nishikawa; Yoshinori Onuki; Koichi Isowa; Kozo Takayama
Formulation optimization of an indomethacin-containing photocrosslinked polyacrylic acid hydrogel as an anti-inflammatory patch.
AAPS PharmSciTech 2008;9(3):1038-45.
2007: Mariko Morishita; Noriyasu Kamei; Jumpei Ehara; Koichi Isowa; Kozo Takayama
A novel approach using functional peptides for efficient intestinal absorption of insulin.
Journal of controlled release : official journal of the Controlled Release Society 2007;118(2):177-84.
2003: Esti Hendradi; Yasuko Obata; Koichi Isowa; Tsuneji Nagai; Kozo Takayama
Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac.
Biological & pharmaceutical bulletin 2003;26(12):1739-43.
2001: Yasuko Obata; Chao Jie Li; Mikito Fujikawa; Kozo Takayama; H Sato; Kimio Higashiyama; Koichi Isowa; Tsuneji Nagai
Evaluation and structure-activity relationship of synthesized cyclohexanol derivatives on percutaneous absorption of ketoprofen using artificial neural network.
International journal of pharmaceutics 2001;212(2):223-31.
2000: Yasuko Obata; H Sato; Chao Jie Li; Kozo Takayama; Kimio Higashiyama; Tsuneji Nagai; Koichi Isowa
Effect of synthesized cyclohexanol derivatives using L-menthol as a lead compound on the percutaneous absorption of ketoprofen.
International journal of pharmaceutics 2000;198(2):191-200.
2000: Yoshinori Onuki; Mariko Morishita; Kozo Takayama; Shinji Tokiwa; Yoshiyuki Chiba; Koichi Isowa; Tsuneji Nagai
In vivo effects of highly purified docosahexaenoic acid on rectal insulin absorption.
International journal of pharmaceutics 2000;198(2):147-56.
2000: Yasuko Obata; T Sesumi; Kozo Takayama; Koichi Isowa; S Grosh; S Wick; R Sitz; Tsuneji Nagai
Evaluation of skin damage caused by percutaneous absorption enhancers using fractal analysis.
Journal of pharmaceutical sciences 2000;89(4):556-61.
1999: Keiko Tsutsumi; Yasuko Obata; Kozo Takayama; Koichi Isowa; Tsuneji Nagai
Permeation of several drugs through keratinized epithelial-free membrane of hamster cheek pouch.
International journal of pharmaceutics 1999;177(1):7-14.
1998: A Suzuki; Mariko Morishita; M Kajita; Kozo Takayama; Koichi Isowa; Yoshiyuki Chiba; Shinji Tokiwa; Tsuneji Nagai
Enhanced colonic and rectal absorption of insulin using a multiple emulsion containing eicosapentaenoic acid and docosahexaenoic acid.
Journal of pharmaceutical sciences 1998;87(10):1196-202.
1998: T Yamamoto; Yoshie Maitani; T Ando; Koichi Isowa; Kozo Takayama; Tsuneji Nagai
High absorbency and subchronic morphologic effects on the nasal epithelium of a nasal insulin powder dosage form with a soybean-derived sterylglucoside mixture in rabbits.
Biological & pharmaceutical bulletin 1998;21(8):866-70.
1995: T Yamamoto; Yoshie Maitani; Koichi Isowa; Tsuneji Nagai
Morphologic examination of rabbit nasal mucosa after the nasal administration of insulin peanut oil suspension and a powder dosage form with soybean-derived sterylglucoside.
Biological & pharmaceutical bulletin 1995;18(6):887-90.
1994: K K Levison; Kozo Takayama; Koichi Isowa; K Okabe; Tsuneji Nagai
Formulation optimization of indomethacin gels containing a combination of three kinds of cyclic monoterpenes as percutaneous penetration enhancers.
Journal of pharmaceutical sciences 1994;83(9):1367-72.
1993: M Kitahara; F Ishiguro; Kozo Takayama; Koichi Isowa; Tsuneji Nagai
Evaluation of skin damage of cyclic monoterpenes, percutaneous absorption enhancers, by using culture human skin cells.
Biological & pharmaceutical bulletin 1993;16(9):912-6.