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Tarik Issad

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Cécile Pierre-Eugene; Norbert Tennagels; G Tschank; Cornelia Hampe; Marion Neuillé; Tuyet Thu Nguyen; Patrick Pagesy; Tarik Issad
Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2.
Melissa Kazantzis; Smitha Kota; Virginia Takahashi; Vladimir Zilberfarb; Mouaadh Abdelkarim; Lotfi Chouchane; Jessica Hinkle; Tarik Issad; Arthur Donny Strosberg
PAZ6 cells constitute a representative model for human brown pre-adipocytes.
Samira Boubekeur; Nicolas Boute; Patrick Pagesy; Vladimir Zilberfarb; Nicolas Christeff; Tarik Issad
A new highly efficient substrate-trapping mutant of protein tyrosine phosphatase 1B (PTP1B) reveals full autoactivation of the insulin receptor precursor.

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All Publications

2012: Cécile Pierre-Eugene; Norbert Tennagels; G Tschank; Cornelia Hampe; Marion Neuillé; Tuyet Thu Nguyen; Patrick Pagesy; Tarik Issad
Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2.
PloS one 2012;7(7):e41992.
2012: Melissa Kazantzis; Smitha Kota; Virginia Takahashi; Vladimir Zilberfarb; Mouaadh Abdelkarim; Lotfi Chouchane; Jessica Hinkle; Tarik Issad; Arthur Donny Strosberg
PAZ6 cells constitute a representative model for human brown pre-adipocytes.
Frontiers in endocrinology 2012;3():13.
2011: Samira Boubekeur; Nicolas Boute; Patrick Pagesy; Vladimir Zilberfarb; Nicolas Christeff; Tarik Issad
A new highly efficient substrate-trapping mutant of protein tyrosine phosphatase 1B (PTP1B) reveals full autoactivation of the insulin receptor precursor.
The Journal of biological chemistry 2011;286(22):19373-80.
2010: Tarik Issad; E Masson; P Pagesy
O-GlcNAc modification, insulin signaling and diabetic complications.
Diabetes & metabolism 2010;36(6 Pt 1):423-35.
2010: Tarik Issad
[O-GlcNAc glycosylation and regulation of cell signaling].
Médecine sciences : M/S 2010;26(8-9):753-9.
2010: Christophe Blanquart; Salah-Eddine Karouri; Tarik Issad
Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration.
Biochemical and biophysical research communications 2010;392(1):83-8.
2009: Christophe Blanquart; Salah-Eddine Karouri; Tarik Issad
Implication of protein tyrosine phosphatase 1B in MCF-7 cell proliferation and resistance to 4-OH tamoxifen.
Biochemical and biophysical research communications 2009;387(4):748-53.
2009: Diana Goenaga; Cornelia Hampe; Nadège Carré; katia cailliau; Edith Browaeys-Poly; Dominique Perdereau; Lowenna J Holt; Roger J Daly; JEAN R GIRARD; Isabelle Broutin; Tarik Issad; Anne-Françoise Burnol
Molecular determinants of Grb14-mediated inhibition of insulin signaling.
Molecular endocrinology (Baltimore, Md.) 2009;23(7):1043-51.
2008: Tarik Issad; Meishiue Kuo
O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity.
Trends in endocrinology and metabolism: TEM 2008;19(10):380-9.
2008: Christophe Blanquart; Josepha Achi; Tarik Issad
Characterization of IRA/IRB hybrid insulin receptors using bioluminescence resonance energy transfer.
Biochemical pharmacology 2008;76(7):873-83.
2008: MeiShiue Kuo; Vladimir Zilberfarb; Nicolas Gangneux; Névéna Christeff; Tarik Issad
O-GlcNAc modification of FoxO1 increases its transcriptional activity: a role in the glucotoxicity phenomenon?
Biochimie 2008;90(5):679-85.
2008: Meishiue Kuo; Vladimir Zilberfarb; Nicolas Gangneux; Névéna Christeff; Tarik Issad
[A new mode of reglulation of FoxO1 by O-GlcNAc glycosylation: involvement in the glucotoxicity phenomenon].
Médecine sciences : M/S 2008;24(4):369-71.
2008: Meishiue Kuo; Vladimir Zilberfarb; Nicolas Gangneux; Névéna Christeff; Tarik Issad
O-glycosylation of FoxO1 increases its transcriptional activity towards the glucose 6-phosphatase gene.
FEBS letters 2008;582(5):829-34.
2007: Luis G Bermúdez-Humarán; Sébastien Nouaille; Vladimir Zilberfarb; Gérard Corthier; Alexandra Gruss; Philippe Langella; Tarik Issad
Effects of intranasal administration of a leptin-secreting Lactococcus lactis recombinant on food intake, body weight, and immune response of mice.
Applied and environmental microbiology 2007;73(16):5300-7.
2007: Tarik Issad; Christophe Blanquart; Carmen Gonzalez-Yanes
The use of bioluminescence resonance energy transfer for the study of therapeutic targets: application to tyrosine kinase receptors.
Expert opinion on therapeutic targets 2007;11(4):541-56.
2006: Sébastien Nouaille; Christophe Blanquart; Vladimir Zilberfarb; Nicolas Boute; Dominique Perdereau; Anne-Françoise Burnol; Tarik Issad
Interaction between the insulin receptor and Grb14: a dynamic study in living cells using BRET.
Biochemical pharmacology 2006;72(11):1355-66.
2006: Christophe Blanquart; Carmen Gonzalez-Yanes; Tarik Issad
Monitoring the activation state of insulin/insulin-like growth factor-1 hybrid receptors using bioluminescence resonance energy transfer.
Molecular pharmacology 2006;70(5):1802-11.
2006: Sébastien Nouaille; Christophe Blanquart; Vladimir Zilberfarb; Nicolas Boute; Dominique Perdereau; Johan Roix; Anne-Françoise Burnol; Tarik Issad
Interaction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptor.
EMBO reports 2006;7(5):512-8.
2006: Tarik Issad; Ralf JOckers
Bioluminescence resonance energy transfer to monitor protein-protein interactions.
Methods in molecular biology (Clifton, N.J.) 2006;332():195-209.
2005: Christophe Blanquart; Nicolas Boute; Daniele Lacasa; Tarik Issad
Monitoring the activation state of the insulin-like growth factor-1 receptor and its interaction with protein tyrosine phosphatase 1B using bioluminescence resonance energy transfer.
Molecular pharmacology 2005;68(3):885-94.
2005: Daniele Lacasa; Nicolas Boute; Tarik Issad
Interaction of the insulin receptor with the receptor-like protein tyrosine phosphatases PTPalpha and PTPepsilon in living cells.
Molecular pharmacology 2005;67(4):1206-13.
2005: Tarik Issad; Nicolas Boute; Samira Boubekeur; Daniele Lacasa
Interaction of PTPB with the insulin receptor precursor during its biosynthesis in the endoplasmic reticulum.
Biochimie 2005;87(1):111-6.
2004: Nicolas Boute; Vladimir Zilberfarb; Luc Camoin; S Bonnafous; Yannick Le Marchand-Brustel; Tarik Issad
The formation of an intrachain disulfide bond in the leptin protein is necessary for efficient leptin secretion.
Biochimie 2004;86(6):351-6.
2003: Tarik Issad; Nicolas Boute; Samira Boubekeur; Daniele Lacasa; Karine Pernet
Looking for an insulin pill? Use the BRET methodology!
Diabetes & metabolism 2003;29(2 Pt 1):111-7.
2003: Nicolas Boute; Samira Boubekeur; Daniele Lacasa; Tarik Issad
Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells.
EMBO reports 2003;4(3):313-9.
2002: Tarik Issad; Nicolas Boute; Karine Pernet
The activity of the insulin receptor assessed by bioluminescence resonance energy transfer.
Annals of the New York Academy of Sciences 2002;973():120-3.
2002: Tarik Issad; Nicolas Boute; Karine Pernet
A homogenous assay to monitor the activity of the insulin receptor using Bioluminescence Resonance Energy Transfer.
Biochemical pharmacology 2002;64(5-6):813-7.
2002: Nicolas Boute; Ralf JOckers; Tarik Issad
The use of resonance energy transfer in high-throughput screening: BRET versus FRET.
Trends in pharmacological sciences 2002;23(8):351-4.
2002: Michèle Guerre-Millo; Alexandra Grosfeld; Tarik Issad
Leptin is a hypoxia-inducible gene.
Obesity research 2002;10(8):856; author reply 857-8.
2002: Najiba Lahlou; Tarik Issad; Yves Lebouc; Jean-Claude Carel; Luc Camoin; Marc Roger; Jean Girard
Mutations in the human leptin and leptin receptor genes as models of serum leptin receptor regulation.
Diabetes 2002;51(6):1980-5.
2002: Alexandra Grosfeld; Vladimir Zilberfarb; Sophie Turban; Jocelyne André; Michèle Guerre-Millo; Tarik Issad
Hypoxia increases leptin expression in human PAZ6 adipose cells.
Diabetologia 2002;45(4):527-30.
2001: Nicolas Boute; Karine Pernet; Tarik Issad
Monitoring the activation state of the insulin receptor using bioluminescence resonance energy transfer.
Molecular pharmacology 2001;60(4):640-5.
2001: Vladimir Zilberfarb; K Siquier; A Donny Strosberg; Tarik Issad
Effect of dexamethasone on adipocyte differentiation markers and tumour necrosis factor-alpha expression in human PAZ6 cells.
Diabetologia 2001;44(3):377-86.
1999: A Donny Strosberg; Tarik Issad
The involvement of leptin in humans revealed by mutations in leptin and leptin receptor genes.
Trends in pharmacological sciences 1999;20(6):227-30.
1999: A Strobel; K Siquier; Vladimir Zilberfarb; A Donny Strosberg; Tarik Issad
Effect of thiazolidinediones on expression of UCP2 and adipocyte markers in human PAZ6 adipocytes.
Diabetologia 1999;42(5):527-33.
1999: Cindy C Gerhardt; J Gros; A Donny Strosberg; Tarik Issad
Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation.
Molecular pharmacology 1999;55(2):255-62.
1998: M Combettes-Souverain; Tarik Issad
Molecular basis of insulin action.
Diabetes & metabolism 1998;24(6):477-89.
1998: A Strobel; M Combettes-Souverain; L Doaré; A Donny Strosberg; Tarik Issad
Rat uncoupling protein 2 (UCP2): expression in obese ventromedial hypothalamus (VMH)-lesioned animals.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1998;22(11):1121-6.
1998: Tarik Issad; A Strobel; Luc Camoin; M Ozata; A Donny Strosberg
[Leptin and puberty in humans: hypothesis of the critical adipose mass revisited].
Diabetes & metabolism 1998;24(4):376-8.
1998: Ralf JOckers; Tarik Issad; Vladimir Zilberfarb; P de Coppet; Stefano Marullo; A Donny Strosberg
Desensitization of the beta-adrenergic response in human brown adipocytes.
Endocrinology 1998;139(6):2676-84.
1998: A Strobel; Tarik Issad; Luc Camoin; M Ozata; A Donny Strosberg
A leptin missense mutation associated with hypogonadism and morbid obesity.
Nature genetics 1998;18(3):213-5.
1997: M Combettes-Souverain; L Pénicaud; Pascal Ferré; Tarik Issad
Increased mitogen-activated protein kinase expression and activity in white adipose tissue of ventromedial hypothalamus-lesioned rats.
Diabetologia 1997;40(5):533-40.
1997: Vladimir Zilberfarb; F Piétri-Rouxel; Ralf JOckers; S Krief; C Delouis; Tarik Issad; A Donny Strosberg
Human immortalized brown adipocytes express functional beta3-adrenoceptor coupled to lipolysis.
Journal of cell science 1997;110 ( Pt 7)():801-7.
1995: Tarik Issad; M Combettes; pascal ferre
Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation.
European journal of biochemistry / FEBS 1995;234(1):108-15.
1995: Tarik Issad; pascal ferre
[Mechanisms of the intracellular effects of insulin].
Diabète & métabolisme 1995;21(1):63-4.
1993: JEAN R GIRARD; Tarik Issad; J Maury; Fabienne Foufelle; C Postic; Armelle Leturque; pascal ferre
Influence of the weaning diet on the changes of glucose metabolism and of insulin sensitivity.
The Proceedings of the Nutrition Society 1993;52(2):325-33.
1993: J Maury; Tarik Issad; Dominique Perdereau; B Gouhot; Pascal Ferré; JEAN R GIRARD
Effect of acarbose on glucose homeostasis, lipogenesis and lipogenic enzyme gene expression in adipose tissue of weaned rats.
Diabetologia 1993;36(6):503-9.
1992: J Maury; A F Burnol; M Loizeau; Tarik Issad; JEAN R GIRARD; Pascal Ferré
Insulin receptor function is preserved in a physiological state of hypoinsulinemia and insulin resistance.
The American journal of physiology 1992;262(6 Pt 1):E818-25.
1990: pascal ferre; Dominique Perdereau; Armelle Leturque; Tarik Issad; C Postic; C Coupe; JEAN R GIRARD
Adaptations of glucose metabolism in white-fat adipocytes at weaning in the rat are concomitant with specific gene expression.
Biochemical Society transactions 1990;18(5):857-8.
1989: Tarik Issad; Pascal Ferré; M Pastor-Anglada; M A Baudon; JEAN R GIRARD
Development of insulin sensitivity in white adipose tissue during the suckling-weaning transition in the rat. Involvement of glucose transport and lipogenesis.
The Biochemical journal 1989;264(1):217-22.
1988: Tarik Issad; C Coupé; M Pastor-Anglada; Pascal Ferré; JEAN R GIRARD
Development of insulin-sensitivity at weaning in the rat. Role of the nutritional transition.
The Biochemical journal 1988;251(3):685-90.
1987: Tarik Issad; Luc Pénicaud; Pascal Ferré; J Kandé; M A Baudon; JEAN R GIRARD
Effects of fasting on tissue glucose utilization in conscious resting rats. Major glucose-sparing effect in working muscles.
The Biochemical journal 1987;246(1):241-4.
1987: Tarik Issad; C Coupe; pascal ferre; JEAN R GIRARD
Insulin resistance during suckling period in rats.
The American journal of physiology 1987;253(2 Pt 1):E142-8.
1987: Luc Pénicaud; Pascal Ferré; J Kande; Armelle Leturque; Tarik Issad; JEAN R GIRARD
Effect of anesthesia on glucose production and utilization in rats.
The American journal of physiology 1987;252(3 Pt 1):E365-9.
1986: Pascal Ferré; J F Decaux; Tarik Issad; J Girard
Changes in energy metabolism during the suckling and weaning period in the newborn.
Reproduction, nutrition, development 1986;26(2B):619-31.