FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Keiji Isshiki

Research Profile

Disorders

Living Beings

Anatomy

Geographic Areas

Japan

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Takashi Uzu; Keiko Nakao; Satoshi Ugi; Hisazumi Araki; Shin-Ichi Araki; Keiji Isshiki; Atsunori Kashiwagi; Hiromichi Kawai; Shinji Kume; Hiroshi Maegawa
High sodium intake is associated with masked hypertension in Japanese patients with type 2 diabetes and treated hypertension.
Masahiro Aoyama; Hisazumi Araki; Shin-Ichi Araki; Masami Chin-Kanasaki; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya; Shinji Kume; Hiroshi Maegawa; Takashi Uzu
Fructose induces tubulointerstitial injury in the kidney of mice.
Takashi Uzu; Atsushi Yamauchi; Daisuke Koya; Shinji Kume; Hiroshi Maegawa; Shin-Ichi Araki; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Yasuo Kida; Ryuichi Kikkawa
The effects of blood pressure control levels on the renoprotection of type 2 diabetic patients without overt proteinuria.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Keiji Isshiki (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Takashi Uzu; Keiko Nakao; Satoshi Ugi; Hisazumi Araki; Shin-Ichi Araki; Keiji Isshiki; Atsunori Kashiwagi; Hiromichi Kawai; Shinji Kume; Hiroshi Maegawa
High sodium intake is associated with masked hypertension in Japanese patients with type 2 diabetes and treated hypertension.
American journal of hypertension 2012;25(11):1170-4.
2012: Masahiro Aoyama; Hisazumi Araki; Shin-Ichi Araki; Masami Chin-Kanasaki; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya; Shinji Kume; Hiroshi Maegawa; Takashi Uzu
Fructose induces tubulointerstitial injury in the kidney of mice.
Biochemical and biophysical research communications 2012;419(2):244-9.
2012: Takashi Uzu; Atsushi Yamauchi; Daisuke Koya; Shinji Kume; Hiroshi Maegawa; Shin-Ichi Araki; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Yasuo Kida; Ryuichi Kikkawa
The effects of blood pressure control levels on the renoprotection of type 2 diabetic patients without overt proteinuria.
Journal of the American Society of Hypertension : JASH 2012;6(2):124-31.
2012: Naoko Deji; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya; Shinji Kume; Hiroshi Maegawa; Akira Nishiyama; Yuki Tanaka; Hisazumi Araki; Shin-ichi Araki; Masami Chin-Kanasaki; Takashi Uzu
Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.
Biochemical and biophysical research communications 2012;418(3):559-64.
2011: Tetsuro Koyama; Shinji Kume; Hiroshi Maegawa; Takeshi Sugaya; Toshiro Sugimoto; Shin-ichi Araki; Masami Chin-Kanasaki; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya; Takashi Uzu
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells.
Free radical biology & medicine 2011;51(6):1258-67.
2011: Takashi Uzu; Shin-ichi Araki; Keiji Isshiki; Hiroshi Maegawa
Furosemide-associated nephrocalcinosis and renal cysts.
Kidney international 2011;80(5):556.
2011: Yuki Tanaka; Shinji Kume; Shin-ichi Araki; Keiji Isshiki; Masami Chin-Kanasaki; Masayoshi Sakaguchi; Toshiro Sugimoto; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Hiroshi Maegawa; Takashi Uzu
Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis.
Kidney international 2011;79(8):871-82.
2011: Xu Yang; Shin-ichi Araki; Masami Chin-Kanasaki; Ping Han; Masakazu Haneda; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya; Shinji Kume; Detian Li; Hiroshi Maegawa; Yoshihiko Nishio; Takeshi Sugaya; Toshiro Sugimoto; Yuki Tanaka; Takashi Uzu
GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice.
PloS one 2011;6(9):e25271.
2010: Mariko Soumura; Shinji Kume; Keiji Isshiki; Naoko Takeda; Shin-ichi Araki; Yuki Tanaka; Toshiro Sugimoto; Masami Chin-Kanasaki; Yoshihiko Nishio; Masakazu Haneda; Daisuke Koya; Atsunori Kashiwagi; Hiroshi Maegawa; Takashi Uzu
Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell.
Biochemical and biophysical research communications 2010;402(2):265-71.
2010: Shinji Kume; Takashi Uzu; Kihachiro Horiike; Masami Chin-Kanasaki; Keiji Isshiki; Shin-Ichi Araki; Toshiro Sugimoto; Masakazu Haneda; Atsunori Kashiwagi; Daisuke Koya
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.
The Journal of clinical investigation 2010;120(4):1043-55.
2010: Takashi Uzu; Yasuo Kida; Nobuo Shirahashi; Tamaki Harada; Atsushi Yamauchi; Makoto Nomura; Keiji Isshiki; Shin-Ichi Araki; Toshiro Sugimoto; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Ryuichi Kikkawa
Cerebral microvascular disease predicts renal failure in type 2 diabetes.
Journal of the American Society of Nephrology : JASN 2010;21(3):520-6.
2010: Jun Nakazawa; Keiji Isshiki; Toshiro Sugimoto; Shin-Ichi Araki; Shinji Kume; Yukiyo Yokomaku; Masami Chin-Kanasaki; Masayoshi Sakaguchi; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Takashi Uzu
Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia-reperfusion-induced acute kidney injury.
Nephrology (Carlton, Vic.) 2010;15(1):93-101.
2009: Shin-ichi Araki; Hiroyuki Matsuno; Masakazu Haneda; Daisuke Koya; Yosuke Kanno; Junko Itho; Akio Kishi; Keiji Isshiki; Toshiro Sugimoto; Hiroshi Maegawa; Atsunori Kashiwagi; Takashi Uzu
Correlation between albuminuria and spontaneous platelet microaggregate formation in type 2 diabetic patients.
Diabetes care 2009;32(11):2062-7.
2009: Takashi Uzu; Masayoshi Sakaguchi; Yukiyo Yokomaku; Shinji Kume; Masami Kanasaki; Keiji Isshiki; Shin-Ichi Araki; Toshiro Sugiomoto; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi
Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker.
Clinical and experimental nephrology 2009;13(4):300-6.
2009: Takashi Uzu; Tsuguru Hatta; Naoko Deji; Tamani Izumiya; Hisami Ueda; Itsuko Miyazawa; Masami Kanasaki; Keiji Isshiki; Toshiji Nishio; Tetsuro Arimura
Target for glycemic control in type 2 diabetic patients on hemodialysis: effects of anemia and erythropoietin injection on hemoglobin A(1c).
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2009;13(2):89-94.
2009: Kunio Hirata; Shinji Kume; Shin-ichi Araki; Masayoshi Sakaguchi; Masami Chin-Kanasaki; Keiji Isshiki; Toshiro Sugimoto; Akira Nishiyama; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Takashi Uzu
Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model.
Biochemical and biophysical research communications 2009;380(1):44-9.
2009: Naoko Deji; Shinji Kume; Shin-Ichi Araki; Mariko Soumura; Toshiro Sugimoto; Keiji Isshiki; Masami Chin-Kanasaki; Masayoshi Sakaguchi; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Takashi Uzu
Structural and functional changes in the kidneys of high-fat diet-induced obese mice.
American journal of physiology. Renal physiology 2009;296(1):F118-26.
2008: Toshiro Sugimoto; Yoshikata Morita; Keiji Isshiki; Takashi Yamamoto; Takashi Uzu; Atsunori Kashiwagi; Minoru Horie; Tohru Asai
Constrictive pericarditis as an emerging manifestation of hyper-IgG4 disease.
International journal of cardiology 2008;130(3):e100-1.
2008: Yukiyo Yokomaku; Toshiro Sugimoto; Shinji Kume; Shin-ichi Araki; Keiji Isshiki; Masami Chin-Kanasaki; Masayoshi Sakaguchi; Norihisa Nitta; Masakazu Haneda; Daisuke Koya; Takashi Uzu; Atsunori Kashiwagi
Asialoerythropoietin prevents contrast-induced nephropathy.
Journal of the American Society of Nephrology : JASN 2008;19(2):321-8.
2008: Shinji Kume; Takashi Uzu; Keiji Isshiki; Daisuke Koya
Peroxisome proliferator-activated receptors in diabetic nephropathy.
PPAR research 2008;2008():879523.
2007: Toshiro Sugimoto; Yuki Tanaka; Keizo Kanasaki; Keiji Isshiki; Uzu Takashi; Daisuke Koya; Atsunori Kashiwagi
Acute nephritic syndrome and polymyalgia rheumatica: coincidental or associated?
Nephrology (Carlton, Vic.) 2007;12(6):625.
2007: Shinji Kume; Takashi Uzu; Shin-ichi Araki; Toshiro Sugimoto; Keiji Isshiki; Masami Chin-Kanasaki; Masayoshi Sakaguchi; Naoto Kubota; Yasuo Terauchi; Takashi Kadowaki; Masakazu Haneda; Atsunori Kashiwagi; Daisuke Koya
Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet.
Journal of the American Society of Nephrology : JASN 2007;18(10):2715-23.
2007: Toshiro Sugimoto; Nobuyuki Ogawa; Masahiro Aoyama; Masayoshi Sakaguchi; Keiji Isshiki; Masami Kanasaki; Takashi Uzu; Yoshihiko Nishio; Yutaka Eguchi; Atsunori Kashiwagi
Haemolytic uraemic syndrome complicated with norovirus-associated gastroenteritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(7):2098-9.
2007: Xiaoxia Wang; Takashi Uzu; Keiji Isshiki; Masami Kanasaki; Kunio Hirata; Mariko Soumura; Jun Nakazawa; Atsunori Kashiwagi; Kiho Takaya; Motohide Isono; Masataka Nishimura; Tsutomu Shikano; Toshiji Nishio; Kobin Tomita; Tetsuro Arimura
Iron status and the use of non-steroidal anti-inflammatory drugs in hemodialysis patients.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2007;11(3):215-9.
2007: Shin-ichi Araki; Masakazu Haneda; Daisuke Koya; Hideki Hidaka; Toshiro Sugimoto; Motohide Isono; Keiji Isshiki; Masami Chin-Kanasaki; Takashi Uzu; Atsunori Kashiwagi
Reduction in microalbuminuria as an integrated indicator for renal and cardiovascular risk reduction in patients with type 2 diabetes.
Diabetes 2007;56(6):1727-30.
2007: Shin-ichi Araki; Masakazu Haneda; Daisuke Koya; Toshiro Sugimoto; Keiji Isshiki; Masami Chin-Kanasaki; Takashi Uzu; Atsunori Kashiwagi
Predictive impact of elevated serum level of IL-18 for early renal dysfunction in type 2 diabetes: an observational follow-up study.
Diabetologia 2007;50(4):867-73.
2007: Takashi Uzu; Masataka Nishimura; Takashi Fujii; Masayoshi Sakaguchi; Masami Kanasaki; Keiji Isshiki; Shin-ichi Araki; Toshiro Sugiomoto; Atsunori Kashiwagi; Genjiro Kimura
Benidipine attenuates glomerular hypertension and reduces albuminuria in patients with metabolic syndrome.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(2):161-5.
2007: Shinji Kume; Masakazu Haneda; Keizo Kanasaki; Toshiro Sugimoto; Shin-ichi Araki; Keiji Isshiki; Motohide Isono; Takashi Uzu; Leonard Guarente; Atsunori Kashiwagi; Daisuke Koya
SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation.
The Journal of biological chemistry 2007;282(1):151-8.
2007: Toshiro Sugimoto; Naoko Deji; Shinji Kume; Norihisa Osawa; Masayoshi Sakaguchi; Keiji Isshiki; Daisuke Koya; Atsunori Kashiwagi
Pulmonary-renal syndrome, diffuse pulmonary hemorrhage and glomerulonephritis, associated with Wegener's granulomatosis effectively treated with early plasma exchange therapy.
Internal medicine (Tokyo, Japan) 2007;46(1):49-53.
2007: Takashi Uzu; T Harada; Masayoshi Sakaguchi; Masami Kanasaki; Keiji Isshiki; Shin-ichi Araki; Toshiro Sugiomoto; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi; Atsushi Yamauchi
Glucocorticoid-induced diabetes mellitus: prevalence and risk factors in primary renal diseases.
Nephron. Clinical practice 2007;105(2):c54-7.
2006: Takashi Uzu; Genjiro Kimura; Atsushi Yamauchi; Masami Kanasaki; Keiji Isshiki; Shin-ichi Araki; Toshiro Sugiomoto; Yoshihiko Nishio; Hiroshi Maegawa; Daisuke Koya; Masakazu Haneda; Atsunori Kashiwagi
Enhanced sodium sensitivity and disturbed circadian rhythm of blood pressure in essential hypertension.
Journal of hypertension 2006;24(8):1627-32.
2006: Shinji Kume; Masakazu Haneda; Keizo Kanasaki; Toshiro Sugimoto; Shin-ichi Araki; Motohide Isono; Keiji Isshiki; Takashi Uzu; Atsunori Kashiwagi; Daisuke Koya
Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation.
Free radical biology & medicine 2006;40(12):2175-82.
2006: Keizo Kanasaki; Masakazu Haneda; Toshiro Sugimoto; Kazuyuki Shibuya; Motohide Isono; Keiji Isshiki; Shin-ichi Araki; Takashi Uzu; Atsunori Kashiwagi; Daisuke Koya
N-acetyl-seryl-aspartyl-lysyl-proline inhibits DNA synthesis in human mesangial cells via up-regulation of cell cycle modulators.
Biochemical and biophysical research communications 2006;342(3):758-65.
2006: Shin-ichi Araki; Masakazu Haneda; Toshiro Sugimoto; Motohide Isono; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya
Polymorphisms of the protein kinase C-beta gene (PRKCB1) accelerate kidney disease in type 2 diabetes without overt proteinuria.
Diabetes care 2006;29(4):864-8.
2006: Masayoshi Sakaguchi; Motohide Isono; Keiji Isshiki; Toshiro Sugimoto; Daisuke Koya; Atsunori Kashiwagi
Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice.
Biochemical and biophysical research communications 2006;340(1):296-301.
2006: Toshiro Sugimoto; Yoshikata Morita; Yukiyo Yokomaku; Keiji Isshiki; Keizo Kanasaki; Yutaka Eguchi; Daisuke Koya; Atsunori Kashiwagi
Systemic cholesterol embolization syndrome associated with myeloperoxidase-anti-neutrophil cytoplasmic antibody.
Internal medicine (Tokyo, Japan) 2006;45(8):557-61.
2005: Shin-ichi Araki; Masakazu Haneda; Toshiro Sugimoto; Motohide Isono; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya
Factors associated with frequent remission of microalbuminuria in patients with type 2 diabetes.
Diabetes 2005;54(10):2983-7.
2005: Masami Chin; Motohide Isono; Keiji Isshiki; Shin-ichi Araki; Toshiro Sugimoto; Baoliang Guo; Haruhisa Sato; Masakazu Haneda; Atsunori Kashiwagi; Daisuke Koya
Estrogen and raloxifene, a selective estrogen receptor modulator, ameliorate renal damage in db/db mice.
The American journal of pathology 2005;166(6):1629-36.
2005: Kazuyuki Shibuya; Keizo Kanasaki; Motohide Isono; Haruhisa Sato; Mitsugu Omata; Toshiro Sugimoto; Shin-ichi Araki; Keiji Isshiki; Atsunori Kashiwagi; Masakazu Haneda; Daisuke Koya
N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice.
Diabetes 2005;54(3):838-45.
2005: Toshiro Sugimoto; Shinji Kume; Norihisa Osawa; Keiji Isshiki; Keizo Kanasaki; Yuki Tanaka; Masami Chin; Kazuyuki Shibuya; Masayoshi Sakaguchi; Shin-ichi Araki; Motohide Isono; Daisuke Koya
[Case of autosomal dominant polycystic kidney disease associated with congenital hepatic fibrosis].
Nihon Jinzo Gakkai shi 2005;47(4):463-7.
2001: Shiro Maeda; Masakazu Haneda; Baoliang Guo; Daisuke Koya; K Hayashi; Toshiro Sugimoto; Keiji Isshiki; Hitoshi Yasuda; Atsunori Kashiwagi; Ryuichi Kikkawa
Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy.
Kidney international 2001;60(4):1428-34.
2001: Toshiro Sugimoto; Masakazu Haneda; H Sawano; Keiji Isshiki; Shiro Maeda; Daisuke Koya; Ken Inoki; Hitoshi Yasuda; Atsunori Kashiwagi; Ryuichi Kikkawa
Endothelin-1 induces cyclooxygenase-2 expression via nuclear factor of activated T-cell transcription factor in glomerular mesangial cells.
Journal of the American Society of Nephrology : JASN 2001;12(7):1359-68.
2000: Keiji Isshiki; Masakazu Haneda; Daisuke Koya; Shiro Maeda; Toshiro Sugimoto; Ryuichi Kikkawa
Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats.
Diabetes 2000;49(6):1022-32.
2000: Daisuke Koya; Masakazu Haneda; Hideaki Nakagawa; Keiji Isshiki; Haruhisa Sato; Shiro Maeda; Toshiro Sugimoto; Hitoshi Yasuda; Atsunori Kashiwagi; DK Ways; George L King; Ryuichi Kikkawa
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(3):439-47.
2000: Keiji Isshiki; Masakazu Haneda; Daisuke Koya; Ryuichi Kikkawa
[Kidney disease and insulin resistance--clinical impact of thiazolidinedione compounds for kidney disease].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(2):440-5.
1999: Shiro Maeda; Masakazu Haneda; Hitoshi Yasuda; T Tachikawa; Keiji Isshiki; Daisuke Koya; Masahiko Terada; Hideki Hidaka; Atsunori Kashiwagi; Ryuichi Kikkawa
Diabetic nephropathy is not associated with the dinucleotide repeat polymorphism upstream of the aldose reductase (ALR2) gene but with erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes.
Diabetes 1999;48(2):420-2.