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Keita Itatsu

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Yasunori Sato; Kenichi Harada; Keita Itatsu; Hiroko Ikeda; Yuko Kakuda; Syuji Shimomura; Xiang Shan Ren; Norihide Yoneda; Motoko Sasaki; Yasuni Nakanuma
Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma.
Junpei Yamaguchi; Motoko Sasaki; Yasunori Sato; Keita Itatsu; Kenichi Harada; Yoh Zen; Hiroko Ikeda; Yuji Nimura; Masato Nagino; Yasuni Nakanuma
Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma.
Motoko Sasaki; Junpei Yamaguchi; Hiroko Ikeda; Keita Itatsu; Yasuni Nakanuma
Polycomb group protein Bmi1 is overexpressed and essential in anchorage-independent colony formation, cell proliferation and repression of cellular senescence in cholangiocarcinoma: tissue and culture studies.

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All Publications

2010: Yasunori Sato; Kenichi Harada; Keita Itatsu; Hiroko Ikeda; Yuko Kakuda; Syuji Shimomura; Xiang Shan Ren; Norihide Yoneda; Motoko Sasaki; Yasuni Nakanuma
Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma.
The American journal of pathology 2010;177(1):141-52.
2010: Junpei Yamaguchi; Motoko Sasaki; Yasunori Sato; Keita Itatsu; Kenichi Harada; Yoh Zen; Hiroko Ikeda; Yuji Nimura; Masato Nagino; Yasuni Nakanuma
Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma.
Cancer science 2010;101(2):355-62.
2009: Motoko Sasaki; Junpei Yamaguchi; Hiroko Ikeda; Keita Itatsu; Yasuni Nakanuma
Polycomb group protein Bmi1 is overexpressed and essential in anchorage-independent colony formation, cell proliferation and repression of cellular senescence in cholangiocarcinoma: tissue and culture studies.
Human pathology 2009;40(12):1723-30.
2009: Junpei Yamaguchi; Motoko Sasaki; Kenichi Harada; Yoh Zen; Yasunori Sato; Hiroko Ikeda; Keita Itatsu; Yukihiro Yokoyama; Hisami Ando; Tetsuo Ohta; Akio Kubota; Koichi Shimizu; Yuji Nimura; Masato Nagino; Yasuni Nakanuma
Papillary hyperplasia of the gallbladder in pancreaticobiliary maljunction represents a senescence-related lesion induced by lysolecithin.
Laboratory investigation; a journal of technical methods and pathology 2009;89(9):1018-31.
2009: Keita Itatsu; Motoko Sasaki; Junpei Yamaguchi; Shusaku Ohira; Akira Ishikawa; Hiroko Ikeda; Yasunori Sato; Kenichi Harada; Yoh Zen; Hiroshi Sato; Tetsuo Ohta; Masato Nagino; Yuji Nimura; Yasuni Nakanuma
Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha.
The American journal of pathology 2009;174(3):829-41.
2009: Motoko Sasaki; Ichiro Araki; Toshiaki Yasui; Masaru Kinoshita; Keita Itatsu; Takayuki Nojima; Yasuni Nakanuma
Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis.
World journal of gastroenterology : WJG 2009;15(5):615-21.
2009: Keita Itatsu; Motoko Sasaki; Kenichi Harada; Junpei Yamaguchi; Hiroko Ikeda; Yasunori Sato; Tetsuo Ohta; Hiroshi Sato; Masato Nagino; Yuji Nimura; Yasuni Nakanuma
Phosphorylation of extracellular signal-regulated kinase 1/2, p38 mitogen-activated protein kinase and nuclear translocation of nuclear factor-kappaB are involved in upregulation of matrix metalloproteinase-9 by tumour necrosis factor-alpha.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(2):291-8.
2008: Motoko Sasaki; Hiroko Ikeda; Keita Itatsu; Junpei Yamaguchi; Seiko Sawada; Hiroshi Minato; Tetsuo Ohta; Yasuni Nakanuma
The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2008;88(8):873-82.
2008: Yoshitsugu Nakanishi; Yoh Zen; Satoshi Kondo; Tomoo Itoh; Keita Itatsu; Yasuni Nakanuma
Expression of cell cycle-related molecules in biliary premalignant lesions: biliary intraepithelial neoplasia and biliary intraductal papillary neoplasm.
Human pathology 2008;39(8):1153-61.
2008: Motoko Sasaki; J Yamaguchi; Keita Itatsu; Hiroko Ikeda; Yasuni Nakanuma
Over-expression of polycomb group protein EZH2 relates to decreased expression of p16 INK4a in cholangiocarcinogenesis in hepatolithiasis.
The Journal of pathology 2008;215(2):175-83.
2008: Keita Itatsu; Yoh Zen; Junpei Yamaguchi; Shusaku Ohira; Akira Ishikawa; Hiroko Ikeda; Yasunori Sato; Kenichi Harada; Motoko Sasaki; Masatoshi Sasaki; Hiroya Sakamoto; Masato Nagino; Yuji Nimura; Tetsuo Ohta; Yasuni Nakanuma
Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts.
Human pathology 2008;39(5):710-9.
2007: Motoko Sasaki; Keita Itatsu; Hiroshi Minato; Hiroyuki Takamura; Tetsuo Ohta; Yasuni Nakanuma
Flare-up of nonalcoholic steatohepatitis after hepatectomy resulted in hepatic failure in a patient with type 2 diabetes mellitus.
Digestive diseases and sciences 2007;52(12):3473-6.
2007: Keita Itatsu; Yoh Zen; Shusaku Ohira; Akira Ishikawa; Yasunori Sato; Kenichi Harada; Hiroko Ikeda; Motoko Sasaki; Yuji Nimura; Yasuni Nakanuma
Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(9):1174-84.
2007: Kenichi Harada; Yasunori Sato; Keita Itatsu; Kumiko Isse; Hiroko Ikeda; Mitsue Yasoshima; Yoh Zen; Akira Matsui; Yasuni Nakanuma
Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia.
Hepatology (Baltimore, Md.) 2007;46(4):1146-54.
2007: Keita Itatsu; Takahiko Fujii; Motoko Sasaki; Yoh Zen; Yasuni Nakanuma
Intraductal papillary cholangiocarcinoma and atypical biliary epithelial lesions confused with intrabiliary extension of metastatic colorectal carcinoma.
Hepato-gastroenterology 2007;54(75):677-80.
2006: Yoh Zen; Takahiko Fujii; Keita Itatsu; Koichi Nakamura; Hiroshi Minato; Satomi Kasashima; Hiroshi Kurumaya; Kazuyoshi Katayanagi; Atsuhiro Kawashima; Shinji Masuda; Hideki Niwa; Takeshi Mitsui; Yasuyuki Asada; Shouji Miura; Tetsuo Ohta; Yasuni Nakanuma
Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas.
Hepatology (Baltimore, Md.) 2006;44(5):1333-43.
2006: Yoh Zen; Takahiko Fujii; Keita Itatsu; Koichi Nakamura; Fumio Konishi; Shinji Masuda; Takeshi Mitsui; Yasuyuki Asada; Shouji Miura; Shiro Miyayama; Takeshi Uehara; Tsutomu Katsuyama; Tetsuo Ohta; Hiroshi Minato; Yasuni Nakanuma
Biliary cystic tumors with bile duct communication: a cystic variant of intraductal papillary neoplasm of the bile duct.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(9):1243-54.
2006: Shusaku Ohira; Keita Itatsu; Motoko Sasaki; Kenichi Harada; Yasunori Sato; Yoh Zen; Akira Ishikawa; Koji Oda; Tetsuro Nagasaka; Yuji Nimura; Yasuni Nakanuma
Local balance of transforming growth factor-beta1 secreted from cholangiocarcinoma cells and stromal-derived factor-1 secreted from stromal fibroblasts is a factor involved in invasion of cholangiocarcinoma.
Pathology international 2006;56(7):381-9.