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Silviu Itescu

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Peter Ghosh; Tony Goldschlager; Stan Gronthos; Robert Moore; Diane Pascoe; Barrie Vernon-Roberts; Andrew Zannettino; Silviu Itescu
Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs.
Fiona See; Tetsunori Seki; Hugo P Sondermeijer; Andrew C W Zannettino; Darren J Kelly; Henry Krum; Paul A Kurlansky; Peter J Psaltis; Michael D Schuster; Klaas M Govaert; Stan Gronthos; Silviu Itescu
Therapeutic effects of human STRO-3-selected mesenchymal precursor cells and their soluble factors in experimental myocardial ischemia.
Nikolaos Bonaros; Silviu Itescu; Timothy P Martens; Thomas Schachner; Bernhard Schlechta; Michael Schuster; Tetsunori Seki; Hugo P Sondermeijer; Dominik Wiedemann; Alfred Kocher
Downregulation of the CXC chemokine receptor 4/stromal cell-derived factor 1 pathway enhances myocardial neovascularization, cardiomyocyte survival, and functional recovery after myocardial infarction.

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2012: Peter Ghosh; Tony Goldschlager; Stan Gronthos; Robert Moore; Diane Pascoe; Barrie Vernon-Roberts; Andrew Zannettino; Silviu Itescu
Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs.
Journal of neurosurgery. Spine 2012;16(5):479-88.
2011: Fiona See; Tetsunori Seki; Hugo P Sondermeijer; Andrew C W Zannettino; Darren J Kelly; Henry Krum; Paul A Kurlansky; Peter J Psaltis; Michael D Schuster; Klaas M Govaert; Stan Gronthos; Silviu Itescu
Therapeutic effects of human STRO-3-selected mesenchymal precursor cells and their soluble factors in experimental myocardial ischemia.
Journal of cellular and molecular medicine 2011;15(10):2117-29.
2011: Nikolaos Bonaros; Silviu Itescu; Timothy P Martens; Thomas Schachner; Bernhard Schlechta; Michael Schuster; Tetsunori Seki; Hugo P Sondermeijer; Dominik Wiedemann; Alfred Kocher
Downregulation of the CXC chemokine receptor 4/stromal cell-derived factor 1 pathway enhances myocardial neovascularization, cardiomyocyte survival, and functional recovery after myocardial infarction.
The Journal of thoracic and cardiovascular surgery 2011;142(3):687-96, 696.e1-2.
2011: Tony Goldschlager; Jeffrey V Rosenfeld; Peter Ghosh; Silviu Itescu; Carl Blecher; Catriona McLean; Graham Jenkin
Cervical interbody fusion is enhanced by allogeneic mesenchymal precursor cells in an ovine model.
Spine 2011;36(8):615-23.
2011: Tony Goldschlager; Silviu Itescu; Jeffrey Victor Rosenfeld; Mark Williamson; Andrew Zannettino; Peter Ghosh; Graham Jenkin
A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model.
Neurosurgery 2011;68(4):1025-34; discussion 1034-5.
2010: Andrew C W Zannettino; Sharon Paton; Silviu Itescu; Stan Gronthos
Comparative assessment of the osteoconductive properties of different biomaterials in vivo seeded with human or ovine mesenchymal stem/stromal cells.
Tissue engineering. Part A 2010;16(12):3579-87.
2010: Peter J Psaltis; Angelo Carbone; Adam J Nelson; Dennis H Lau; Troy Jantzen; Jim Manavis; Kerry Williams; Silviu Itescu; Prashanthan Sanders; Stan Gronthos; Andrew C W Zannettino; Stephen G Worthley
Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experimental nonischemic cardiomyopathy.
JACC. Cardiovascular interventions 2010;3(9):974-83.
2010: Tony Goldschlager; Peter Ghosh; Andrew Zannettino; Stan Gronthos; Jeffrey V Rosenfeld; Silviu Itescu; Graham Jenkin
Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model.
Neurosurgical focus 2010;28(6):E4.
2010: P J Psaltis; S Paton; F See; A Arthur; S Martin; Silviu Itescu; S G Worthley; Stan Gronthos; Andrew C W Zannettino
Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations.
Journal of cellular physiology 2010;223(2):530-40.
2010: Nabil Dib; Philippe Menasche; Jozef J Bartunek; Andreas M Zeiher; Andre Terzic; Nicolas A Chronos; Timothy D Henry; Nicholas S Peters; Francisco Fernández-Avilés; Magdi Yacoub; Timothy A Sanborn; Anthony Demaria; Richard A Schatz; Doris A Taylor; Shmuel Fuchs; Silviu Itescu; Leslie W Miller; Jonathan H Dinsmore; George D Dangas; Jeffrey J Popma; Jennifer L Hall; David R Holmes
Recommendations for successful training on methods of delivery of biologics for cardiac regeneration: a report of the International Society for Cardiovascular Translational Research.
JACC. Cardiovascular interventions 2010;3(3):265-75.
2010: Peter Ghosh; Jiehua Wu; Susan Shimmon; Andrew Cw Zannettino; Stan Gronthos; Silviu Itescu
Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells.
Arthritis research & therapy 2010;12(1):R28.
2009: Piotr Witkowski; Hugo Sondermeijer; Mark A Hardy; David C Woodland; Keagan Lee; Govind Bhagat; Kajetan Witkowski; Fiona See; Abbas Rana; Antonella Maffei; Silviu Itescu; Paul E Harris
Islet grafting and imaging in a bioengineered intramuscular space.
Transplantation 2009;88(9):1065-74.
2009: Stan Gronthos; Rosa McCarty; Krzysztof Mrozik; Stephen Fitter; Sharon Paton; Danijela Menicanin; Silviu Itescu; P Mark Bartold; Cory J Xian; Andrew C W Zannettino
Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues.
Stem cells and development 2009;18(9):1253-62.
2009: Eric K Ho; George Vlad; Adriana I Colovai; Elena R Vasilescu; Joseph Schwartz; Hugo Sondermeijer; Elizabeth Burke; Charles C Marboe; Silviu Itescu; Nicole Suciu-Foca; Donna Mancini
Alloantibodies in heart transplantation.
Human immunology 2009;70(10):825-9.
2009: Jennifer A Dixon; Robert C Gorman; Robert E Stroud; Shenikqua Bouges; Hamamoto Hirotsugu; Joseph H Gorman; Timothy P Martens; Silviu Itescu; Michael D Schuster; Theodore Plappert; Martin G St John-Sutton; Francis G Spinale
Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction.
Circulation 2009;120(11 Suppl):S220-9.
2009: Hirotsugu Hamamoto; Joseph H Gorman; Liam P Ryan; Robin Hinmon; Timothy P Martens; Michael D Schuster; Theodore Plappert; Matti Kiupel; Martin St John Sutton; Silviu Itescu; Robert Gorman
Allogeneic mesenchymal precursor cell therapy to limit remodeling after myocardial infarction: the effect of cell dosage.
The Annals of thoracic surgery 2009;87(3):794-801.
2008: Jason C Kovacic; Peter Macdonald; Michael P Feneley; David W M Muller; Judith Freund; Anthony Dodds; Sam Milliken; Helen Tao; Silviu Itescu; John Moore; David Ma; Robert M Graham
Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD133+ cell infusion in patients with chronic refractory ischemic heart disease: the G-CSF in angina patients with IHD to stimulate neovascularization (GAIN I) trial.
American heart journal 2008;156(5):954-63.
2008: Andrew C W Zannettino; S Paton; A Arthur; Fiona S L Khor; Silviu Itescu; Jeffrey M Gimble; Stan Gronthos
Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo.
Journal of cellular physiology 2008;214(2):413-21.
2007: Stan Gronthos; Stephen Fitter; Peter Diamond; Paul J Simmons; Silviu Itescu; Andrew C W Zannettino
A novel monoclonal antibody (STRO-3) identifies an isoform of tissue nonspecific alkaline phosphatase expressed by multipotent bone marrow stromal stem cells.
Stem cells and development 2007;16(6):953-63.
2007: Piotr Witkowski; Tetsunori Seki; Guosheng Xiang; Timothy P Martens; Hugo P Sondermeijer; Fiona See; Govind Bhagat; Michael Schuster; Mark A Hardy; Silviu Itescu
A DNA enzyme against plasminogen activator inhibitor- type 1 (PAI-1) limits neointima formation after angioplasty in an obese diabetic rodent model.
Journal of cardiovascular pharmacology 2007;50(6):633-40.
2007: Andrew C W Zannettino; Sharon Paton; Angela Kortesidis; Fiona S L Khor; Silviu Itescu; Stan Gronthos
Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45(-)/glycophorin-A-bone marrow cells.
Haematologica 2007;92(12):1707-8.
2007: Khalid Almuti; Jennifer Haythe; Edward Dwyer; Silviu Itescu; Elizabeth Burke; Philip Green; Charles C Marboe; Donna Mancini
The changing pattern of humoral rejection in cardiac transplant recipients.
Transplantation 2007;84(4):498-503.
2007: George Vlad; Eric K Ho; Elena R Vasilescu; Jianshe Fan; Zhuoru Liu; J W Cai; Z Jin; E Burke; M Deng; Martin Cadeiras; Raffaello Cortesini; Silviu Itescu; Charles C Marboe; Donna Mancini; Nicole Suciu-Foca
Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation.
Transplant immunology 2007;18(1):13-21.
2007: Andrew N Morritt; Susan K Bortolotto; Rodney Dilley; XiaoLian Han; Andrew R Kompa; David McCombe; Christine E Wright; Silviu Itescu; James A Angus; Wayne A Morrison
Cardiac tissue engineering in an in vivo vascularized chamber.
Circulation 2007;115(3):353-60.
2006: Andrew Boyle; Robert Whitbourn; Stephen Schlicht; Henry Krum; Alfred Kocher; Harshal H Nandurkar; Steven Bergmann; Mark Daniell; Justin O'Day; Donna Skerrett; David Haylock; Richard E Gilbert; Silviu Itescu
Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: a 12-month follow-up.
International journal of cardiology 2006;109(1):21-7.
2006: Alfred Kocher; Michael D Schuster; Nikolaos Bonaros; Katherine Lietz; Guosheng Xiang; Timothy P Martens; P A Kurlansky; Hugo P Sondermeijer; Piotr Witkowski; Andrew Boyle; Shunichi Homma; S F Wang; Silviu Itescu
Myocardial homing and neovascularization by human bone marrow angioblasts is regulated by IL-8/Gro CXC chemokines.
Journal of molecular and cellular cardiology 2006;40(4):455-64.
2006: Timothy P Martens; Fiona See; Michael D Schuster; Hugo P Sondermeijer; Marco M Hefti; Andrew C W Zannettino; Stan Gronthos; Tetsunori Seki; Silviu Itescu
Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium.
Nature clinical practice. Cardiovascular medicine 2006;3 Suppl 1():S18-22.
2006: Elaine F Reed; Anthony J Demetris; Elizabeth Hammond; Silviu Itescu; Jon A Kobashigawa; Nancy L Reinsmoen; E Rene Rodriguez; Marlene Rose; Susan Stewart; Nicole Suciu-Foca; Adriana Zeevi; Michael C Fishbein
Acute antibody-mediated rejection of cardiac transplants.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006;25(2):153-9.
2006: Do Eun Kim; Eun Jung Lee; Timothy P Martens; Rina Kara; Hina W Chaudhry; Silviu Itescu; Kevin D Costa
Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():849-52.
2005: Guosheng Xiang; Tetsunori Seki; Michael D Schuster; Piotr Witkowski; Andrew Boyle; Fiona See; Timothy P Martens; Alfred Kocher; Hugo P Sondermeijer; Henry Krum; Silviu Itescu
Catalytic degradation of vitamin D up-regulated protein 1 mRNA enhances cardiomyocyte survival and prevents left ventricular remodeling after myocardial ischemia.
The Journal of biological chemistry 2005;280(47):39394-402.
2005: Susan Stewart; Gayle L Winters; Michael C Fishbein; Henry D Tazelaar; Jon Kobashigawa; Jacki Abrams; Claus B Andersen; Annalisa Angelini; Gerald J Berry; Margaret M Burke; Anthony J Demetris; Elizabeth Hammond; Silviu Itescu; Charles C Marboe; Bruce McManus; Elaine F Reed; Nancy L Reinsmoen; E Rene Rodriguez; Alan G Rose; Marlene Rose; Nicole Suciu-Focia; Adriana Zeevi; Margaret Billingham
Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005;24(11):1710-20.
2005: Katherine Lietz; Ranjit John; Elizabeth Burke; Michael Schuster; Tyson B Rogers; Nicole Suciu-Foca; Donna Mancini; Silviu Itescu
Immunoglobulin M-to-immunoglobulin G anti-human leukocyte antigen class II antibody switching in cardiac transplant recipients is associated with an increased risk of cellular rejection and coronary artery disease.
Circulation 2005;112(16):2468-76.
2005: Steve Xydas; Jane K Yang; Elizabeth Burke; Jonathan M Chen; Linda J Addonizio; Seema Mital; Silviu Itescu; Daphne Hsu; Jacqueline Lamour
Utility of post-transplant anti-HLA antibody measurements in pediatric cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005;24(9):1289-96.
2005: Guosheng Xiang; Michael D Schuster; Tetsunori Seki; Piotr Witkowski; Shawdee Eshghi; Silviu Itescu
Downregulated expression of plasminogen activator inhibitor-1 augments myocardial neovascularization and reduces cardiomyocyte apoptosis after acute myocardial infarction.
Journal of the American College of Cardiology 2005;46(3):536-41.
2005: Andrew Boyle; Darren J Kelly; Yuan Zhang; Alison J Cox; Renae M Gow; Kerrie Way; Silviu Itescu; Henry Krum; Richard E Gilbert
Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction.
Journal of molecular and cellular cardiology 2005;39(2):213-21.
2005: Matthew McKay; Sean P Pinney; Simon Gorwara; Elizabeth Burke; Robert R Sciacca; Mark Apfelbaum; Donna Mancini; Silviu Itescu; LeRoy E Rabbani
Anti-human leukocyte antigen antibodies are associated with restenosis after percutaneous coronary intervention for cardiac allograft vasculopathy.
Transplantation 2005;79(11):1581-7.
2005: Darren J Kelly; Yuan Zhang; Renae M Gow; Silviu Itescu; Richard E Gilbert
Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2005;2(2):76-80.
2005: Andrew Boyle; Michael Schuster; Piotr Witkowski; Guosheng Xiang; Tetsunori Seki; Kerrie Way; Silviu Itescu
Additive effects of endothelial progenitor cells combined with ACE inhibition and beta-blockade on left ventricular function following acute myocardial infarction.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2005;6(1):33-7.
2004: Guosheng Xiang; Michael D Schuster; Tetsunori Seki; Alfred Kocher; Shawdee Eshghi; Andrew Boyle; Silviu Itescu
Down-regulation of plasminogen activator inhibitor 1 expression promotes myocardial neovascularization by bone marrow progenitors.
The Journal of experimental medicine 2004;200(12):1657-66.
2004: Fiona See; Walter Thomas; Kerrie Way; Alex Tzanidis; Andrew R Kompa; Dion Lewis; Silviu Itescu; Henry Krum
p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat.
Journal of the American College of Cardiology 2004;44(8):1679-89.
2004: Michael D Schuster; Alfred Kocher; Tetsunori Seki; Timothy P Martens; Guosheng Xiang; Shunichi Homma; Silviu Itescu
Myocardial neovascularization by bone marrow angioblasts results in cardiomyocyte regeneration.
American journal of physiology. Heart and circulatory physiology 2004;287(2):H525-32.
2004: Elena R Vasilescu; Eric K Ho; Ludwika de la Torre; Silviu Itescu; Charles C Marboe; Raffaello Cortesini; Nicole Suciu-Foca; Donna Mancini
Anti-HLA antibodies in heart transplantation.
Transplant immunology 2004;12(2):177-83.
2003: Donna Mancini; Sean P Pinney; Daniel Burkhoff; John LaManca; Silviu Itescu; Elizabeth Burke; Niloo Edwards; Mehmet C Oz; Andrew R Marks
Use of rapamycin slows progression of cardiac transplantation vasculopathy.
Circulation 2003;108(1):48-53.
2003: Silviu Itescu; Alfred Kocher; Michael D Schuster
Myocardial neovascularization by adult bone marrow-derived angioblasts: strategies for improvement of cardiomyocyte function.
Heart failure reviews 2003;8(3):253-8.
2003: Silviu Itescu; Ranjit John
Interactions between the recipient immune system and the left ventricular assist device surface: immunological and clinical implications.
The Annals of thoracic surgery 2003;75(6 Suppl):S58-65.
2003: Silviu Itescu; Michael D Schuster; Alfred Kocher
New directions in strategies using cell therapy for heart disease.
Journal of molecular medicine (Berlin, Germany) 2003;81(5):288-96.
2003: Katherine Lietz; Ranjit John; Ainat Beniaminovitz; Elizabeth Burke; Nicole Suciu-Foca; Donna M Mancini; Niloo M Edwards; Silviu Itescu
Interleukin-2 receptor blockade in cardiac transplantation: influence of HLA-DR locus incompatibility on treatment efficacy.
Transplantation 2003;75(6):781-7.
2003: Ranjit John; Katherine Lietz; Michael Schuster; Yoshifumi Naka; Vivek Rao; Donna M Mancini; Eric A Rose; Craig R Smith; Mehmet C Oz; Niloo M Edwards; Silviu Itescu
Immunologic sensitization in recipients of left ventricular assist devices.
The Journal of thoracic and cardiovascular surgery 2003;125(3):578-91.
2003: Silviu Itescu; Michael Schuster; Elizabeth Burke; Jan Ankersmit; Alfred Kocher; Mario Deng; Ranjit John; Katherine Lietz
Immunobiologic consequences of assist devices.
Cardiology clinics 2003;21(1):119-33, ix-x.
2002: Katherine Lietz; Ranjit John; Michael Schuster; Jan Ankersmit; Elizabeth Burke; Nicole Suciu-Foca; Niloo Edwards; Donna Mancini; Silviu Itescu
Mycophenolate mofetil reduces anti-HLA antibody production and cellular rejection in heart transplant recipients.
Transplantation proceedings 2002;34(5):1828-9.
2002: Mario C Deng; Gabriele Plenz; Carlos A Labarrere; Charles C Marboe; Hideo A Baba; Michael Erre; Silviu Itescu
The role of IL6 cytokines in acute cardiac allograft rejection.
Transplant immunology 2002;9(2-4):115-20.
2002: Silviu Itescu; Elizabeth Burke; Katherine Lietz; Ranjit John; Donna Mancini; Robert Michler; Eric Rose; Mehmet C Oz; Niloo Edwards
Intravenous pulse administration of cyclophosphamide is an effective and safe treatment for sensitized cardiac allograft recipients.
Circulation 2002;105(10):1214-9.
2002: Michael Schuster; Alfred Kocher; Ranjit John; Marion Hoffman; Jan Ankersmit; Katherine Lietz; Niloo Edwards; Mehmet C Oz; Silviu Itescu
B-cell activation and allosensitization after left ventricular assist device implantation is due to T-cell activation and CD40 ligand expression.
Human immunology 2002;63(3):211-20.
2002: Silviu Itescu; Alfred Kocher; Michael D Schuster
Myocardial neovascularization by adult bone marrow-derived angioblasts: strategies for improvement of cardiomyocyte function.
Annals of hematology 2002;81 Suppl 2():S21-5.
2001: Katherine Lietz; Ranjit John; Alfred Kocher; Michael Schuster; Donna M Mancini; Niloo M Edwards; Silviu Itescu
Increased prevalence of autoimmune phenomena and greater risk for alloreactivity in female heart transplant recipients.
Circulation 2001;104(12 Suppl 1):I177-83.
2001: Hendrik Jan Ankersmit; Robert Deicher; Bernhard Moser; I Teufel; Georg Roth; Sabine Gerlitz; Silviu Itescu; Ernst Wolner; George Boltz-Nitulescu; Josef Kovarik
Impaired T cell proliferation, increased soluble death-inducing receptors and activation-induced T cell death in patients undergoing haemodialysis.
Clinical and experimental immunology 2001;125(1):142-8.
2001: Alfred Kocher; Michael D Schuster; Matthias Szabolcs; Shin Takuma; Daniel Burkhoff; Jack Wang; Shunichi Homma; Niloo M Edwards; Silviu Itescu
Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function.
Nature medicine 2001;7(4):430-6.
2001: Michael Schuster; Alfred Kocher; Katherine Lietz; Jan Ankersmit; Ranjit John; Niloo Edwards; Mehmet C Oz; Silviu Itescu
Induction of CD40 ligand expression in human T cells by biomaterials derived from left ventricular assist device surface.
Transplantation proceedings 2001;33(1-2):1960-1.
2001: Michael Schuster; Jan Ankersmit; Alfred Kocher; Katherine Lietz; N Schuster; M Hofmann; Ranjit John; Niloo Edwards; Mehmet C Oz; Silviu Itescu
Induction of T-cell apoptosis by polyurethane biomaterials used in left ventricular assist devices is dependent on calcineurin activation.
Transplantation proceedings 2001;33(1-2):1958-9.
2001: Katherine Lietz; Ainat Beniaminovitz; Elizabeth Burke; Ranjit John; Alfred Kocher; Michael Schuster; Donna Mancini; Niloo Edwards; Silviu Itescu
Influence of donor-recipient HLA-DR matching on efficacy of anti-CD25 mAb in cardiac transplantation.
Transplantation proceedings 2001;33(1-2):1018.
2001: Katherine Lietz; Ranjit John; Elizabeth Burke; Alfred Kocher; Michael Schuster; Nicole Suciu-Foca; Donna Mancini; Niloo Edwards; Silviu Itescu
Increased risk for cardiac allograft rejection in recipients with HLA-B8, DR3 type.
Transplantation proceedings 2001;33(1-2):481-2.
2001: Larry L Schulman; AD Weinberg; CC McGregor; Nicole Suciu-Foca; Silviu Itescu
Influence of donor and recipient HLA locus mismatching on development of obliterative bronchiolitis after lung transplantation.
American journal of respiratory and critical care medicine 2001;163(2):437-42.
2001: Ranjit John; Hiranya A Rajasinghe; Silviu Itescu; S Suratwala; S Suratwalla; Katherine Lietz; Alan D Weinberg; Alfred Kocher; Donna M Mancini; Ronald Drusin; Mehmet C Oz; Craig R Smith; Eric A Rose; Niloo M Edwards
Factors affecting long-term survival (>10 years) after cardiac transplantation in the cyclosporine era.
Journal of the American College of Cardiology 2001;37(1):189-94.
2000: Ranjit John; Hiranya A Rajasinghe; Jonathan M Chen; Alan D Weinberg; Prashant Sinha; Silviu Itescu; Katherine Lietz; Donna Mancini; Mehmet C Oz; Craig R Smith; Eric A Rose; Niloo M Edwards
Impact of current management practices on early and late death in more than 500 consecutive cardiac transplant recipients.
Annals of surgery 2000;232(3):302-11.
2000: Silviu Itescu; Pawel Kwiatkowski; John H Artrip; Alfred Kocher; Niloo Edwards; Robert Michler
Transendothelial migration and infiltration of porcine xenografts by primate monocytes requires natural killer cell-dependent activation.
Transplantation proceedings 2000;32(5):1083.
2000: Pawel Kwiatkowski; John H Artrip; Robert Michler; SF Wang; IF McKenzie; MS Sandrin; Silviu Itescu
Human monocytes bind to ligands on porcine endothelium containing the gal alpha (1,3)-Gal antigen.
Transplantation proceedings 2000;32(5):931.
2000: Ranjit John; Pawel Kwiatkowski; Niloo Edwards; SF Wang; Silviu Itescu
Human natural killer cells augment B cell responses to porcine xenoantigens.
Transplantation proceedings 2000;32(5):928.
2000: Pawel Kwiatkowski; John H Artrip; SF Wang; Robert Michler; Silviu Itescu
Human monocytes bind to two distinct carbohydrate capping structures on porcine endothelium.
Transplantation proceedings 2000;32(5):927.
2000: Silviu Itescu; Jan Ankersmit; Alfred Kocher; Michael D Schuster
Immunobiology of left ventricular assist devices.
Progress in cardiovascular diseases 2000;43(1):67-80.
2000: Ainat Beniaminovitz; Silviu Itescu; Katherine Lietz; M Donovan; Elizabeth Burke; B D Groff; Niloo Edwards; Donna M Mancini
Prevention of rejection in cardiac transplantation by blockade of the interleukin-2 receptor with a monoclonal antibody.
The New England journal of medicine 2000;342(9):613-9.
1999: Alfred Kocher; Marek Ehrlich; Cäsar Khazen; Jan Ankersmit; F Nourani; Silviu Itescu; Niloo M Edwards; Ernst Wolner; Günther Laufer
Repair of an aortic aneurysm at the time of heart transplantation: report of two cases and review of the literature.
Transplantation proceedings 1999;31(8):3184-6.
1999: Ranjit John; Katherine Lietz; Elizabeth Burke; Jan Ankersmit; Donna Mancini; Nicole Suciu-Foca; Niloo Edwards; Eric Rose; Mehmet C Oz; Silviu Itescu
Intravenous immunoglobulin reduces anti-HLA alloreactivity and shortens waiting time to cardiac transplantation in highly sensitized left ventricular assist device recipients.
Circulation 1999;100(19 Suppl):II229-35.
1999: Hendrik Jan Ankersmit; Niloo M Edwards; Michael Schuster; Ranjit John; Alfred Kocher; Eric A Rose; Mehmet C Oz; Silviu Itescu
Quantitative changes in T-cell populations after left ventricular assist device implantation: relationship to T-cell apoptosis and soluble CD95.
Circulation 1999;100(19 Suppl):II211-5.
1999: Hendrik Jan Ankersmit; S Tugulea; Talia B Spanier; Alan D Weinberg; John H Artrip; Elizabeth Burke; Margaret Flannery; Donna Mancini; Eric A Rose; Niloo M Edwards; Mehmet C Oz; Silviu Itescu
Activation-induced T-cell death and immune dysfunction after implantation of left-ventricular assist device.
Lancet 1999;354(9178):550-5.
1999: John H Artrip; Pawel Kwiatkowski; Robert Michler; SF Wang; S Tugulea; Jan Ankersmit; L Chisholm; IF McKenzie; MS Sandrin; Silviu Itescu
Target cell susceptibility to lysis by human natural killer cells is augmented by alpha(1,3)-galactosyltransferase and reduced by alpha(1, 2)-fucosyltransferase.
The Journal of biological chemistry 1999;274(16):10717-22.
1999: Ranjit John; Jonathan M Chen; Alan Weinberg; Mehmet C Oz; Donna Mancini; Silviu Itescu; Mark E Galantowicz; Craig R Smith; Eric A Rose; Niloo M Edwards
Long-term survival after cardiac retransplantation: a twenty-year single-center experience.
The Journal of thoracic and cardiovascular surgery 1999;117(3):543-55.
1999: Pawel Kwiatkowski; John H Artrip; Niloo M Edwards; Katherine Lietz; S Tugulea; Robert Michler; IF McKenzie; MS Sandrin; Silviu Itescu
High-level porcine endothelial cell expression of alpha(1,2)-fucosyltransferase reduces human monocyte adhesion and activation.
Transplantation 1999;67(2):219-26; discussion 193-4.
1999: Pawel Kwiatkowski; John H Artrip; Ranjit John; Niloo M Edwards; S F Wang; Robert Michler; Silviu Itescu
Induction of swine major histocompatibility complex class I molecules on porcine endothelium by tumor necrosis factor-alpha reduces lysis by human natural killer cells.
Transplantation 1999;67(2):211-8.
1999: Niloo M Edwards; Hiranya A Rajasinghe; Ranjit John; Jonathan M Chen; Silviu Itescu; Donna M Mancini
Cardiac transplantation in over 1000 patients: a single institution experience from Columbia University.
Clinical transplants 1999;():249-61.
1998: Nicole Suciu-Foca; Rodica Ciubotariu; Silviu Itescu; Eric A Rose; Raffaello Cortesini
Indirect allorecognition of donor HLA-DR peptides in chronic rejection of heart allografts.
Transplantation proceedings 1998;30(8):3999-4000.
1998: N Moazami; Silviu Itescu; M R Williams; Michael Argenziano; A Weinberg; Mehmet C Oz
Platelet transfusions are associated with the development of anti-major histocompatibility complex class I antibodies in patients with left ventricular assist support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1998;17(9):876-80.
1998: Silviu Itescu; T C Tung; Elizabeth Burke; Alan Weinberg; N Moazami; John H Artrip; Nicole Suciu-Foca; Eric A Rose; Mehmet C Oz; Robert Michler
Preformed IgG antibodies against major histocompatibility complex class II antigens are major risk factors for high-grade cellular rejection in recipients of heart transplantation.
Circulation 1998;98(8):786-93.
1998: Silviu Itescu; T C Tung; Elizabeth Burke; Alan D Weinberg; Donna Mancini; Robert Michler; Nicole Suciu-Foca; Eric A Rose
An immunological algorithm to predict risk of high-grade rejection in cardiac transplant recipients.
Lancet 1998;352(9124):263-70.
1998: Larry L Schulman; AD Weinberg; C McGregor; Mark E Galantowicz; Nicole Suciu-Foca; Silviu Itescu
Mismatches at the HLA-DR and HLA-B loci are risk factors for acute rejection after lung transplantation.
American journal of respiratory and critical care medicine 1998;157(6 Pt 1):1833-7.
1998: Silviu Itescu; Pawel Kwiatkowski; John H Artrip; S F Wang; Jan Ankersmit; OP Minanov; Robert Michler
Role of natural killer cells, macrophages, and accessory molecule interactions in the rejection of pig-to-primate xenografts beyond the hyperacute period.
Human immunology 1998;59(5):275-86.
1998: OP Minanov; John H Artrip; Matthias Szabolcs; Pawel Kwiatkowski; U Galili; Silviu Itescu; Robert Michler
Triple immunosuppression reduces mononuclear cell infiltration and prolongs graft life in pig-to-newborn baboon cardiac xenotransplantation.
The Journal of thoracic and cardiovascular surgery 1998;115(5):998-1006.
1998: Pawel Kwiatkowski; John H Artrip; Jan Ankersmit; M Schuster; Ranjit John; SF Wang; N Ma; Robert Michler; Silviu Itescu
Importance of CD49d-VCAM interactions in human monocyte adhesion to porcine endothelium.
Xenotransplantation 1998;5(1):67-74.
1998: Rodica Ciubotariu; Z Liu; Adriana I Colovai; Eric Ho; Silviu Itescu; S Ravalli; Mark A Hardy; Raffaello Cortesini; Eric A Rose; Nicole Suciu-Foca
Persistent allopeptide reactivity and epitope spreading in chronic rejection of organ allografts.
The Journal of clinical investigation 1998;101(2):398-405.
1998: S Masroor; Silviu Itescu; John H Artrip; OP Minanov; R Buelow; Robert Michler
Induction of tolerance in rodent cardiac allotransplantation using an MHC class I-derived peptide and cyclosporin A.
The Annals of thoracic surgery 1998;65(1):144-8.
1997: Robert Michler; OP Minanov; John H Artrip; Silviu Itescu
Immature host for xenotransplantation.
World journal of surgery 1997;21(9):924-31.
1997: S Tugulea; Rodica Ciubotariu; Adriana I Colovai; Zhuoru Liu; Silviu Itescu; Larry L Schulman; Peter E Fisher; Mark A Hardy; Eric A Rose; Robert Michler; Raffaello Cortesini; Nicole Suciu-Foca
New strategies for early diagnosis of heart allograft rejection.
Transplantation 1997;64(6):842-7.
1997: John H Artrip; Silviu Itescu; OP Minanov; Pawel Kwiatkowski; Robert Michler
Cardiac xenotransplantation.
Current opinion in cardiology 1997;12(2):172-8.
1997: OP Minanov; Silviu Itescu; F A Neethling; A S Morgenthau; Pawel Kwiatkowski; D K Cooper; Robert Michler
Anti-GaL IgG antibodies in sera of newborn humans and baboons and its significance in pig xenotransplantation.
Transplantation 1997;63(2):182-6.
1997: B Kwiatkowski; John H Artrip; Robert Michler; Silviu Itescu
Human NK cells demonstrate increased adherence and lysis of porcine endothelium following activation with IL-2.
Annals of transplantation : quarterly of the Polish Transplantation Society 1997;2(1):21-5.
1997: Silviu Itescu; John H Artrip; Pawel Kwiatkowski; S F Wang; OP Minanov; A S Morgenthau; Robert Michler
Lysis of pig endothelium by IL-2 activated human natural killer cells is inhibited by swine and human major histocompatibility complex (MHC) class I gene products.
Annals of transplantation : quarterly of the Polish Transplantation Society 1997;2(1):14-20.
1997: John H Artrip; Pawel Kwiatkowski; Robert Michler; Silviu Itescu
Immunologic barriers in pig-to-primate cardiac xenotransplantation.
Annals of transplantation : quarterly of the Polish Transplantation Society 1997;2(1):5-11.
1996: Silviu Itescu; Pawel Kwiatkowski; SF Wang; T Blood; OP Minanov; S Rose; Robert Michler
Circulating human mononuclear cells exhibit augmented lysis of pig endothelium after activation with interleukin 2.
Transplantation 1996;62(12):1927-33.
1996: Robert Michler; A S Shah; Silviu Itescu; D P O'Hair; S Tugulea; Pawel Kwiatkowski; Z Liu; Jeffrey L Platt; Eric A Rose; Nicole Suciu-Foca
The influence of concordant xenografts on the humoral and cell-mediated immune responses to subsequent allografts in primates.
The Journal of thoracic and cardiovascular surgery 1996;112(4):1002-9.
1996: A S Shah; Silviu Itescu; D P O'Hair; S Tugulea; Pawel Kwiatkowski; Z Liu; Jeffrey L Platt; Eric A Rose; Nicole Suciu-Foca; Robert Michler
Importance of cell-mediated immune responses in rejection of concordant heart xenografts in primates.
Transplantation proceedings 1996;28(2):775-6.
1996: A S Shah; Silviu Itescu; D P O'Hair; S Tugulea; Pawel Kwiatkowski; Z Liu; Jeffrey L Platt; Eric A Rose; Nicole Suciu-Foca; Robert Michler
Immunologic studies in primates undergoing concordant xenotransplantation as a bridge allotransplantation.
Transplantation proceedings 1996;28(2):745-6.
1996: Robert Michler; H Xu; D P O'Hair; A Shah; Pawel Kwiatkowski; OP Minanov; Silviu Itescu
Newborn discordant cardiac xenotransplantation in primates: a model of natural antibody depletion.
Transplantation proceedings 1996;28(2):651-2.
1996: Jane H Morse; Robyn J Barst; Silviu Itescu; E R Flaster; GITA SINHA; Y Zhang; M Fotino
Primary pulmonary hypertension in HIV infection: an outcome determined by particular HLA class II alleles.
American journal of respiratory and critical care medicine 1996;153(4 Pt 1):1299-301.
1996: OP Minanov; Silviu Itescu; Robert Michler
Recent advances and the potential for clinical use of xenotransplantation.
Current opinion in cardiology 1996;11(2):214-20.
1996: Silviu Itescu
Adult immunodeficiency and rheumatic disease.
Rheumatic diseases clinics of North America 1996;22(1):53-73.
1996: Robert Michler; Jonathan M Chen; Silviu Itescu; Donna M Mancini; Mehmet C Oz; Craig R Smith; Eric A Rose
Two decades of cardiac transplantation at the Columbia-Presbyterian Medical Center: 1977-1997.
Clinical transplants 1996;():153-65.
1995: Robert Michler; D P O'Hair; H Xu; A S Shah; Silviu Itescu
Newborn baboon immunity: lessons in cross-species transplantation.
The Annals of thoracic surgery 1995;60(6 Suppl):S582-4.
1995: Silviu Itescu; S Rose; E Dwyer; Robert Winchester
Grouping HLA-B locus serologic specificities according to shared structural motifs suggests that different peptide-anchoring pockets may have contrasting influences on the course of HIV-1 infection.
Human immunology 1995;42(1):81-9.
1994: Silviu Itescu; S Rose; E Dwyer; Robert Winchester
Certain HLA-DR5 and -DR6 major histocompatibility complex class II alleles are associated with a CD8 lymphocytic host response to human immunodeficiency virus type 1 characterized by low lymphocyte viral strain heterogeneity and slow disease progression.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11472-6.
1994: Silviu Itescu; P F Simonelli; R J Winchester; H S Ginsberg
Human immunodeficiency virus type 1 strains in the lungs of infected individuals evolve independently from those in peripheral blood and are highly conserved in the C-terminal region of the envelope V3 loop.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11378-82.
1993: E Dwyer; Silviu Itescu; Robert Winchester
Characterization of the primary structure of T cell receptor beta chains in cells infiltrating the salivary gland in the sicca syndrome of HIV-1 infection. Evidence of antigen-driven clonal selection suggested by restricted combinations of V beta J beta gene segment usage and shared somatically encoded amino acid residues.
The Journal of clinical investigation 1993;92(1):495-502.
1993: Silviu Itescu; J Dalton; H Z Zhang; Robert Winchester
Tissue infiltration in a CD8 lymphocytosis syndrome associated with human immunodeficiency virus-1 infection has the phenotypic appearance of an antigenically driven response.
The Journal of clinical investigation 1993;91(5):2216-25.
1992: Silviu Itescu
Diffuse infiltrative lymphocytosis syndrome in children and adults infected with HIV-1: a model of rheumatic illness caused by acquired viral infection.
American journal of reproductive immunology (New York, N.Y. : 1989) 1992;28(3-4):247-50.
1992: Silviu Itescu; Robert Winchester
Diffuse infiltrative lymphocytosis syndrome: a disorder occurring in human immunodeficiency virus-1 infection that may present as a sicca syndrome.
Rheumatic diseases clinics of North America 1992;18(3):683-97.