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Koreaki Ito
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29
Akiyama, Yoshinori
23
Mori, Hiroyuki
12
Nakatogawa, Hitoshi
8
Inaba, Kenji
7
Kihara, A
6
Takahashi, Yoh-hei
5
Matsuo, E
4
Ito, Yoshiaki
4
Kanehara, Kazue
4
Tsukazaki, Tomoya
4
Vassylyev, Dmitry
4
Yoshihisa, T
3
Satoh, Yasunari
3
Huang, Gang
3
Saikawa, Naoya
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All Publications
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2009: Otsuka S; Aoyama T; Furu M; Ito K; Jin Y; Nasu A; Fukiage K; Kohno Y; Maruyama T; Kanaji T; Nishiura A; Sugihara H; Fujimura S; Otsuka T; Nakamura T; Toguchida J
PGE2 signal via EP2 receptors evoked by a selective agonist enhances regeneration of injured articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(4):529-38.
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2009: Inaba Kenji; Murakami Satoshi; Nakagawa Atsushi; Iida Hiroka; Kinjo Mai; Ito Koreaki; Suzuki Mamoru
Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB.
The EMBO journal 2009;28(6):779-91.
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2008: Inaba Kenji; Suzuki Mamoru; Maegawa Ken-ichi; Akiyama Shuji; Ito Koreaki; Akiyama Yoshinori
A pair of circularly permutated PDZ domains control RseP, the S2P family intramembrane protease of Escherichia coli.
The Journal of biological chemistry 2008;283(50):35042-52.
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2008: Tsukazaki Tomoya; Mori Hiroyuki; Fukai Shuya; Ishitani Ryuichiro; Mori Takaharu; Dohmae Naoshi; Perederina Anna; Sugita Yuji; Vassylyev Dmitry G; Ito Koreaki; Nureki Osamu
Conformational transition of Sec machinery inferred from bacterial SecYE structures.
Nature 2008;455(7215):988-91.
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2008: Ito Koreaki; Inaba Kenji
The disulfide bond formation (Dsb) system.
Current opinion in structural biology 2008;18(4):450-8.
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2008: Koide Kayo; Ito Koreaki; Akiyama Yoshinori
Substrate recognition and binding by RseP, an Escherichia coli intramembrane protease.
The Journal of biological chemistry 2008;283(15):9562-70.
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2008: Inaba Kenji; Ito Koreaki
Structure and mechanisms of the DsbB-DsbA disulfide bond generation machine.
Biochimica et biophysica acta 2008;1783(4):520-9.
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2008: Muto Hiroki; Ito Koreaki
Peptidyl-prolyl-tRNA at the ribosomal P-site reacts poorly with puromycin.
Biochemical and biophysical research communications 2008;366(4):1043-7.
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2007: Ito Koreaki
[Finding of translocon]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(12):1480-31.
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2007: Inaba Kenji; Ito Koreaki
[Structural basis for disulfide bond generation in the cell]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(8):853-61.
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2007: Maegawa Saki; Koide Kayo; Ito Koreaki; Akiyama Yoshinori
The intramembrane active site of GlpG, an E. coli rhomboid protease, is accessible to water and hydrolyses an extramembrane peptide bond of substrates.
Molecular microbiology 2007;64(2):435-47.
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2007: Koide Kayo; Maegawa Saki; Ito Koreaki; Akiyama Yoshinori
Environment of the active site region of RseP, an Escherichia coli regulated intramembrane proteolysis protease, assessed by site-directed cysteine alkylation.
The Journal of biological chemistry 2007;282(7):4553-60.
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2007: Shimohata Nobuyuki; Nagamori Shushi; Akiyama Yoshinori; Kaback H Ronald; Ito Koreaki
SecY alterations that impair membrane protein folding and generate a membrane stress.
The Journal of cell biology 2007;176(3):307-17.
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2006: Muto Hiroki; Ito Koreaki
[New concepts gained from the study of SecM, a secretion monitor protein]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(16 Suppl):2583-9.
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2006: Vassylyev Dmitry G; Mori Hiroyuki; Vassylyeva Marina N; Tsukazaki Tomoya; Kimura Yoshiaki; Tahirov Tahir H; Ito Koreaki
Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer.
Journal of molecular biology 2006;364(3):248-58.
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2006: Inaba Kenji; Murakami Satoshi; Suzuki Mamoru; Nakagawa Atsushi; Yamashita Eiki; Okada Kengo; Ito Koreaki
Crystal structure of the DsbB-DsbA complex reveals a mechanism of disulfide bond generation.
Cell 2006;127(4):789-801.
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2006: Mori Hiroyuki; Ito Koreaki
The long alpha-helix of SecA is important for the ATPase coupling of translocation.
The Journal of biological chemistry 2006;281(47):36249-56.
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2006: Mori Hiroyuki; Ito Koreaki
Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16159-64.
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2006: Vassylyeva Marina N; Mori Hiroyuki; Tsukazaki Tomoya; Yokoyama Shigeyuki; Tahirov Tahir H; Ito Koreaki; Vassylyev Dmitry G
Cloning, expression, purification, crystallization and initial crystallographic analysis of the preprotein translocation ATPase SecA from Thermus thermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 9):909-12.
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2006: Takahashi Yoh-Hei; Inaba Kenji; Ito Koreaki
Role of the cytosolic loop of DsbB in catalytic turnover of the ubiquinone-DsbB complex.
Antioxidants & redox signaling 2006;8(5-6):743-52.
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2006: Ito Koreaki
Redox control of protein processing: from electrons to cells.
Antioxidants & redox signaling 2006;8(5-6):729-30.
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2006: Muto Hiroki; Nakatogawa Hitoshi; Ito Koreaki
Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.
Molecular cell 2006;22(4):545-52.
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2006: Tsukazaki Tomoya; Mori Hiroyuki; Fukai Shuya; Numata Tomoyuki; Perederina Anna; Adachi Hiroaki; Matsumura Hiroyoshi; Takano Kazufumi; Murakami Satoshi; Inoue Tsuyoshi; Mori Yusuke; Sasaki Takatomo; Vassylyev Dmitry G; Nureki Osamu; Ito Koreaki
Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 4):376-80.
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2006: Chiba Shinobu; Ito Koreaki; Akiyama Yoshinori
The Escherichia coli plasma membrane contains two PHB (prohibitin homology) domain protein complexes of opposite orientations.
Molecular microbiology 2006;60(2):448-57.
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2006: Inaba Kenji; Takahashi Yoh-hei; Ito Koreaki; Hayashi Shigehiko
Critical role of a thiolate-quinone charge transfer complex and its adduct form in de novo disulfide bond generation by DsbB.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(2):287-92.
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2005: Maegawa Saki; Ito Koreaki; Akiyama Yoshinori
Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane.
Biochemistry 2005;44(41):13543-52.
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2005: Sakoh Machiko; Ito Koreaki; Akiyama Yoshinori
Proteolytic activity of HtpX, a membrane-bound and stress-controlled protease from Escherichia coli.
The Journal of biological chemistry 2005;280(39):33305-10.
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2005: Inaba Kenji; Takahashi Yoh-Hei; Ito Koreaki
Reactivities of quinone-free DsbB from Escherichia coli.
The Journal of biological chemistry 2005;280(38):33035-44.
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2005: Ito Koreaki
Ribosome-based protein folding systems are structurally divergent but functionally universal across biological kingdoms.
Molecular microbiology 2005;57(2):313-7.
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2005: Shimohata Nobuyuki; Akiyama Yoshinori; Ito Koreaki
Peculiar properties of DsbA in its export across the Escherichia coli cytoplasmic membrane.
Journal of bacteriology 2005;187(12):3997-4004.
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2005: Nakatogawa Hitoshi; Murakami Akiko; Mori Hiroyuki; Ito Koreaki
SecM facilitates translocase function of SecA by localizing its biosynthesis.
Genes & development 2005;19(4):436-44.
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2005: Ito Koreaki; Akiyama Yoshinori
Cellular functions, mechanism of action, and regulation of FtsH protease.
Annual review of microbiology 2005;59():211-31.
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2004: Akiyama Yoshinori; Kanehara Kazue; Ito Koreaki
RseP (YaeL), an Escherichia coli RIP protease, cleaves transmembrane sequences.
The EMBO journal 2004;23(22):4434-42.
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2004: Takahashi Yoh-hei; Inaba Kenji; Ito Koreaki
Characterization of the menaquinone-dependent disulfide bond formation pathway of Escherichia coli.
The Journal of biological chemistry 2004;279(45):47057-65.
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2004: Murakami Akiko; Nakatogawa Hitoshi; Ito Koreaki
Translation arrest of SecM is essential for the basal and regulated expression of SecA.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(33):12330-5.
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2004: Mori Hiroyuki; Shimokawa Naomi; Satoh Yasunari; Ito Koreaki
Mutational analysis of transmembrane regions 3 and 4 of SecY, a central component of protein translocase.
Journal of bacteriology 2004;186(12):3960-9.
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2004: Nakatogawa Hitoshi; Ito Koreaki
[The functions of the ribosomal tunnel in a birth of proteins]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2004;49(7 Suppl):829-33.
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2004: Nakatogawa Hitoshi; Murakami Akiko; Ito Koreaki
Control of SecA and SecM translation by protein secretion.
Current opinion in microbiology 2004;7(2):145-50.
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2004: Saikawa Naoya; Akiyama Yoshinori; Ito Koreaki
FtsH exists as an exceptionally large complex containing HflKC in the plasma membrane of Escherichia coli.
Journal of structural biology 2004;146(1-2):123-9.
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2004: Inaba Kenji; Takahashi Yoh-hei; Fujieda Nobutaka; Kano Kenji; Miyoshi Hideto; Ito Koreaki
DsbB elicits a red-shift of bound ubiquinone during the catalysis of DsbA oxidation.
The Journal of biological chemistry 2004;279(8):6761-8.
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2004: Nakatogawa Hitoshi; Ito Koreaki
Intraribosomal regulation of expression and fate of proteins.
Chembiochem : a European journal of chemical biology 2004;5(1):48-51.
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2003: Kanehara Kazue; Ito Koreaki; Akiyama Yoshinori
YaeL proteolysis of RseA is controlled by the PDZ domain of YaeL and a Gln-rich region of RseA.
The EMBO journal 2003;22(23):6389-98.
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2003: Satoh Yasunari; Mori Hiroyuki; Ito Koreaki
Nearest neighbor analysis of the SecYEG complex. 2. Identification of a SecY-SecE cytosolic interface.
Biochemistry 2003;42(24):7442-7.
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2003: Satoh Yasunari; Matsumoto Gen; Mori Hiroyuki; Ito Koreaki
Nearest neighbor analysis of the SecYEG complex. 1. Identification of a SecY-SecG interface.
Biochemistry 2003;42(24):7434-41.
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2003: Shimokawa N; Mori H; Ito K
Importance of transmembrane segments in Escherichia coli SecY.
Molecular genetics and genomics : MGG 2003;269(2):180-7.
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2003: Akiyama Yoshinori; Ito Koreaki
Reconstitution of membrane proteolysis by FtsH.
The Journal of biological chemistry 2003;278(20):18146-53.
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2003: Mori Hiroyuki; Tsukazaki Tomoya; Masui Ryoji; Kuramitsu Seiki; Yokoyama Shigeyuki; Johnson Arthur E; Kimura Yoshiaki; Akiyama Yoshinori; Ito Koreaki
Fluorescence resonance energy transfer analysis of protein translocase. SecYE from Thermus thermophilus HB8 forms a constitutive oligomer in membranes.
The Journal of biological chemistry 2003;278(16):14257-64.
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2003: Nakatogawa Hitoshi; Ito Koreaki
[Translation arrest and its involvement in protein translocation across membranes]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(4 Suppl):338-45.
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2003: Matsuo E; Mori H; Ito K
Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states.
Molecular genetics and genomics : MGG 2003;268(6):808-15.
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2003: Laursen Brian Søgaard; Siwanowicz Igor; Larigauderie Guilhem; Hedegaard Jakob; Ito Koreaki; Nakamura Yoshikazu; Kenney John M; Mortensen Kim Kusk; Sperling-Petersen Hans Uffe
Characterization of mutations in the GTP-binding domain of IF2 resulting in cold-sensitive growth of Escherichia coli.
Journal of molecular biology 2003;326(2):543-51.
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2003: Mori Hiroyuki; Akiyama Yoshinori; Ito Koreaki
A SecE mutation that modulates SecY-SecE translocase assembly, identified as a specific suppressor of SecY defects.
Journal of bacteriology 2003;185(3):948-56.
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2003: Mori Hiroyuki; Ito Koreaki
Biochemical characterization of a mutationally altered protein translocase: proton motive force stimulation of the initiation phase of translocation.
Journal of bacteriology 2003;185(2):405-12.
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2002: Mori Hiroyuki; Shimizu Yuhsuke; Ito Koreaki
Superactive SecY variants that fulfill the essential translocation function with a reduced cellular quantity.
The Journal of biological chemistry 2002;277(50):48550-7.
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2002: Chiba Shinobu; Akiyama Yoshinori; Ito Koreaki
Membrane protein degradation by FtsH can be initiated from either end.
Journal of bacteriology 2002;184(17):4775-82.
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2002: Kanehara Kazue; Ito Koreaki; Akiyama Yoshinori
YaeL (EcfE) activates the sigma(E) pathway of stress response through a site-2 cleavage of anti-sigma(E), RseA.
Genes & development 2002;16(16):2147-55.
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2002: Shimohata Nobuyuki; Chiba Shinobu; Saikawa Naoya; Ito Koreaki; Akiyama Yoshinori
The Cpx stress response system of Escherichia coli senses plasma membrane proteins and controls HtpX, a membrane protease with a cytosolic active site.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(7):653-62.
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2002: Inaba Kenji; Ito Koreaki
Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade.
The EMBO journal 2002;21(11):2646-54.
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2002: Chiba Kazuhiko; Mori Hiroyuki; Ito Koreaki
Roles of the C-terminal end of SecY in protein translocation and viability of Escherichia coli.
Journal of bacteriology 2002;184(8):2243-50.
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2002: Nakatogawa Hitoshi; Ito Koreaki
The ribosomal exit tunnel functions as a discriminating gate.
Cell 2002;108(5):629-36.
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2002: Saikawa Naoya; Ito Koreaki; Akiyama Yoshinori
Identification of glutamic acid 479 as the gluzincin coordinator of zinc in FtsH (HflB).
Biochemistry 2002;41(6):1861-8.
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2001: Kanehara K; Akiyama Y; Ito K
Characterization of the yaeL gene product and its S2P-protease motifs in Escherichia coli.
Gene 2001;281(1-2):71-9.
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2001: Akiyama Y; Ito K
Roles of homooligomerization and membrane association in ATPase and proteolytic activities of FtsH in vitro.
Biochemistry 2001;40(25):7687-93.
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2001: Mori H; Ito K
An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):5128-33.
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2001: Kihara A; Akiyama Y; Ito K
Revisiting the lysogenization control of bacteriophage lambda. Identification and characterization of a new host component, HflD.
The Journal of biological chemistry 2001;276(17):13695-700.
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2001: Huang G; Shigesada K; Ito K; Wee H J; Yokomizo T; Ito Y
Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation.
The EMBO journal 2001;20(4):723-33.
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2001: Nakatogawa H; Ito K
Secretion monitor, SecM, undergoes self-translation arrest in the cytosol.
Molecular cell 2001;7(1):185-92.
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2001: Kobayashi T; Takahashi Y; Ito K
Identification of a segment of DsbB essential for its respiration-coupled oxidation.
Molecular microbiology 2001;39(1):158-65.
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2000: Matsumoto G; Nakatogawa H; Mori H; Ito K
Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(12):991-9.
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2000: Nakatogawa H; Mori H; Ito K
Two independent mechanisms down-regulate the intrinsic SecA ATPase activity.
The Journal of biological chemistry 2000;275(43):33209-12.
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2000: Zhang Y W; Yasui N; Ito K; Huang G; Fujii M; Hanai J; Nogami H; Ochi T; Miyazono K; Ito Y
A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10549-54.
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2000: Akiyama Y; Ito K
Roles of multimerization and membrane association in the proteolytic functions of FtsH (HflB).
The EMBO journal 2000;19(15):3888-95.
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2000: Chiba S; Akiyama Y; Mori H; Matsuo E; Ito K
Length recognition at the N-terminal tail for the initiation of FtsH-mediated proteolysis.
EMBO reports 2000;1(1):47-52.
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2000: Matsumoto G; Homma T; Mori H; Ito K
A mutation in secY that causes enhanced SecA insertion and impaired late functions in protein translocation.
Journal of bacteriology 2000;182(12):3377-82.
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2000: Nakatogawa H; Mori H; Matsumoto G; Ito K
Characterization of a mutant form of SecA that alleviates a SecY defect at low temperature and shows a synthetic defect with SecY alteration at high temperature.
Journal of biochemistry 2000;127(6):1071-9.
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1999: Matsuo E; Sampei G; Mizobuchi K; Ito K
The plasmid F OmpP protease, a homologue of OmpT, as a potential obstacle to E. coli-based protein production.
FEBS letters 1999;461(1-2):6-8.
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1999: Kohzaki H; Ito K; Huang G; Wee H J; Murakami Y; Ito Y
Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.
Oncogene 1999;18(28):4055-62.
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1999: Kihara A; Akiyama Y; Ito K
Dislocation of membrane proteins in FtsH-mediated proteolysis.
The EMBO journal 1999;18(11):2970-81.
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1999: Kobayashi T; Ito K
Respiratory chain strongly oxidizes the CXXC motif of DsbB in the Escherichia coli disulfide bond formation pathway.
The EMBO journal 1999;18(5):1192-8.
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1998: Matsumoto G; Mori H; Ito K
Roles of SecG in ATP- and SecA-dependent protein translocation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13567-72.
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1998: Kihara A; Ito K
Translocation, folding, and stability of the HflKC complex with signal anchor topogenic sequences.
The Journal of biological chemistry 1998;273(45):29770-5.
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1998: Akiyama Y; Kihara A; Mori H; Ogura T; Ito K
Roles of the periplasmic domain of Escherichia coli FtsH (HflB) in protein interactions and activity modulation.
The Journal of biological chemistry 1998;273(35):22326-33.
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1998: Matsuo E; Mori H; Shimoike T; Ito K
Syd, a SecY-interacting protein, excludes SecA from the SecYE complex with an altered SecY24 subunit.
The Journal of biological chemistry 1998;273(30):18835-40.
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1998: Chen L F; Ito K; Murakami Y; Ito Y
The capacity of polyomavirus enhancer binding protein 2alphaB (AML1/Cbfa2) to stimulate polyomavirus DNA replication is related to its affinity for the nuclear matrix.
Molecular and cellular biology 1998;18(7):4165-76.
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1998: Matsuo E; Ito K
Genetic analysis of an essential cytoplasmic domain of Escherichia coli SecY based on resistance to Syd, a SecY-interacting protein.
Molecular & general genetics : MGG 1998;258(3):240-9.
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1998: Akiyama Y; Ehrmann M; Kihara A; Ito K
Polypeptide binding of Escherichia coli FtsH (HflB).
Molecular microbiology 1998;28(4):803-12.
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1998: Kihara A; Akiyama Y; Ito K
Different pathways for protein degradation by the FtsH/HflKC membrane-embedded protease complex: an implication from the interference by a mutant form of a new substrate protein, YccA.
Journal of molecular biology 1998;279(1):175-88.
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1998: Sone M; Ito K
[Cellular machinery for the introduction of disulfide bonds to proteins]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(1):1-10.
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1997: Matsumoto G; Yoshihisa T; Ito K
SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane.
The EMBO journal 1997;16(21):6384-93.
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1997: Kobayashi T; Kishigami S; Sone M; Inokuchi H; Mogi T; Ito K
Respiratory chain is required to maintain oxidized states of the DsbA-DsbB disulfide bond formation system in aerobically growing Escherichia coli cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11857-62.
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1997: Taura T; Yoshihisa T; Ito K
Protein translocation functions of Escherichia coli SecY: in vitro characterization of cold-sensitive secY mutants.
Biochimie 1997;79(8):517-21.
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1997: Homma T; Yoshihisa T; Ito K
Subunit interactions in the Escherichia coli protein translocase: SecE and SecG associate independently with SecY.
FEBS letters 1997;408(1):11-5.
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1997: Kihara A; Akiyama Y; Ito K
Host regulation of lysogenic decision in bacteriophage lambda: transmembrane modulation of FtsH (HflB), the cII degrading protease, by HflKC (HflA).
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5544-9.
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1997: Sone M; Akiyama Y; Ito K
Differential in vivo roles played by DsbA and DsbC in the formation of protein disulfide bonds.
The Journal of biological chemistry 1997;272(16):10349-52.
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1997: Sone M; Kishigami S; Yoshihisa T; Ito K
Roles of disulfide bonds in bacterial alkaline phosphatase.
The Journal of biological chemistry 1997;272(10):6174-8.
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1997: Ito K; Kawanishi S
Photoinduced hydroxylation of deoxyguanosine in DNA by pterins: sequence specificity and mechanism.
Biochemistry 1997;36(7):1774-81.
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