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Kazuhiro Ito

Research Profile

Disorders

Chemicals & Drugs

Phenomena

Acetylation

Activities & Behaviors

Smoking

Physiology

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Publications

TOP 3
Yoshiki Kobayashi; Shin'ichiro Mikura; Christos Rossios; Dai Takagi; Hiroo Wada; Peter J Barnes; Hajime Goto; Manabu Higaki; Kazuhiro Ito
A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition.
Andriana I Papaioannou; Christos Rossios; Konstantinos Kostikas; Kazuhiro Ito
Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions.
Patrick Mallia; Simon D Message; Gregory Oleszkiewicz; Alberto Papi; Rosa Sotero; Luminita A Stanciu; Maria-Belen Trujillo-Torralbo; Tatiana Kebadze; Onn Min Kon; Ian M Adcock; Julia Aniscenko; Peter J Barnes; Marco Contoli; Sarah L Elkin; Joseph Footitt; Katrina Gray; Kazuhiro Ito; Annette Jepson; Malcolm Johnson; Sebastian L Johnston
Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease.

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All Publications

2013: Yoshiki Kobayashi; Shin'ichiro Mikura; Christos Rossios; Dai Takagi; Hiroo Wada; Peter J Barnes; Hajime Goto; Manabu Higaki; Kazuhiro Ito
A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition.
The Journal of pharmacology and experimental therapeutics 2013;345(1):76-84.
2013: Andriana I Papaioannou; Christos Rossios; Konstantinos Kostikas; Kazuhiro Ito
Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions.
Current drug targets 2013;14(2):149-57.
2012: Patrick Mallia; Simon D Message; Gregory Oleszkiewicz; Alberto Papi; Rosa Sotero; Luminita A Stanciu; Maria-Belen Trujillo-Torralbo; Tatiana Kebadze; Onn Min Kon; Ian M Adcock; Julia Aniscenko; Peter J Barnes; Marco Contoli; Sarah L Elkin; Joseph Footitt; Katrina Gray; Kazuhiro Ito; Annette Jepson; Malcolm Johnson; Sebastian L Johnston
Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2012;186(11):1117-24.
2012: Christos Rossios; Yasuo To; P J Barnes; Misako Ito; G Osoata; Kazuhiro Ito
Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition.
British journal of pharmacology 2012;167(4):775-86.
2012: Yoshiki Kobayashi; Nicolas Mercado; Anna Miller-Larsson; Peter J Barnes; Kazuhiro Ito
Increased corticosteroid sensitivity by a long acting β2 agonist formoterol via β2 adrenoceptor independent protein phosphatase 2A activation.
Pulmonary pharmacology & therapeutics 2012;25(3):201-7.
2012: Masako To; Satoshi Yamamura; Kenichi Akashi; Peter J Barnes; Catherine E Charron; Kazuhiro Ito
Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7.
Chest 2012;141(5):1233-42.
2012: Kazuhiro Ito; Thomas Colley; Nicolas Mercado
Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease.
International journal of chronic obstructive pulmonary disease 2012;7():641-52.
2012: Nicolas Mercado; Omar S Usmani; Yoshiki Kobayashi; Sally Meah; Peter J Barnes; Kian Fan Chung; Amir Hakim; Kazuhiro Ito
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma.
PloS one 2012;7(7):e41582.
2012: Katsuyuki Tomita; Peter J Barnes; Gaetano Caramori; K Fan Chung; Borja Cosio; Kazuhiro Ito; Sam Lim; Timothy Oates; Hiroyuki Sano; Yuji Tohda; Ian M Adcock
STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects.
Journal of inflammation (London, England) 2012;9():5.
2011: Nicholas Mercado; Yasuo To; Ian M Adcock; Peter J Barnes; Yoshiki Kobayashi; Kazuhiro Ito
p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma.
Molecular pharmacology 2011;80(6):1128-35.
2011: Sarah Essilfie-Quaye; Kazuhiro Ito; Misako Ito; Sergei A Kharitonov; Peter J Barnes
Comparison of Symbicort® versus Pulmicort® on steroid pharmacodynamic markers in asthma patients.
Respiratory medicine 2011;105(12):1784-9.
2011: Christos Rossios; Masako To; Yasuo To; Ian M Adcock; Peter J Barnes; Misako Ito; Malcolm Johnson; Kazuhiro Ito
Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells.
European journal of pharmacology 2011;670(1):244-51.
2011: Masako To; Pilar M Ausin; Kazuhiro Ito; Sergei A Kharitonov; Peter J Barnes
Osteoprotegerin in sputum is a potential biomarker in COPD.
Chest 2011;140(1):76-83.
2011: Gaetano Caramori; Ian M Adcock; Paolo Casolari; Kazuhiro Ito; Elen Jazrawi; Loukia Tsaprouni; Gino Villetti; Maurizio Civelli; Chiara Carnini; Kian Fan Chung; Peter J Barnes; Alberto Papi
Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer.
Thorax 2011;66(6):521-7.
2011: Nicolas Mercado; Yasuo To; Kazuhiro Ito; Peter J Barnes
Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ.
The Journal of pharmacology and experimental therapeutics 2011;337(2):465-70.
2011: Nicolas Mercado; Rajesh K Thimmulappa; Catherine M R Thomas; Peter S Fenwick; Kirandeep K Chana; Louise E Donnelly; Shyam Biswal; Kazuhiro Ito; Peter J Barnes
Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress.
Biochemical and biophysical research communications 2011;406(2):292-8.
2011: Loukia Tsaprouni; Kazuhiro Ito; Jonathan J Powell; Ian M Adcock; Neville A Punchard
Differential patterns of histone acetylation in inflammatory bowel diseases.
Journal of inflammation (London, England) 2011;8(1):1.
2010: Yasuo To; Kazuhiro Ito; Yasuo Kizawa; Marco Failla; Misako Ito; Tadashi Kusama; W Mark Elliott; James C Hogg; Ian M Adcock; Peter J Barnes
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2010;182(7):897-904.
2010: Caterina Brindicci; Sergei A Kharitonov; Misako Ito; Mark W Elliott; James C Hogg; Peter J Barnes; Kazuhiro Ito
Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2010;181(1):21-30.
2009: Catherine E Charron; Pai-Chien Chou; David J C Coutts; Vaibhav Kumar; Masako To; Kenichi Akashi; Liao Pinhu; Mark Griffiths; Ian M Adcock; Peter J Barnes; Kazuhiro Ito
Hypoxia-inducible factor 1alpha induces corticosteroid-insensitive inflammation via reduction of histone deacetylase-2 transcription.
The Journal of biological chemistry 2009;284(52):36047-54.
2009: Kazuhiro Ito; Nicolas Mercado
Therapeutic targets for new therapy for corticosteroid refractory asthma.
Expert opinion on therapeutic targets 2009;13(9):1053-67.
2009: Yuji Nakamaru; Chaitanya Vuppusetty; Hiroo Wada; Jill C Milne; Misako Ito; Christos Rossios; Mark Elliot; James Hogg; Sergei A Kharitonov; Hajime Goto; Jean E Bemis; Peter Elliott; Peter J Barnes; Kazuhiro Ito
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):2810-9.
2009: Grace O Osoata; Satoshi Yamamura; Misako Ito; Chaitanya Vuppusetty; Ian M Adcock; Peter J Barnes; Kazuhiro Ito
Nitration of distinct tyrosine residues causes inactivation of histone deacetylase 2.
Biochemical and biophysical research communications 2009;384(3):366-71.
2009: Grace O Osoata; Toyoyuki Hanazawa; Caterina Brindicci; Misako Ito; Peter J Barnes; Sergei A Kharitonov; Kazuhiro Ito
Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine.
Chest 2009;135(6):1513-20.
2009: Kittipong Maneechotesuwan; Xin Yao; Kazuhiro Ito; Elen Jazrawi; Omar S Usmani; Ian M Adcock; Peter J Barnes
Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease.
PLoS medicine 2009;6(5):e1000076.
2009: John A Marwick; Gaetano Caramori; Christopher S Stevenson; Paolo Casolari; Elen Jazrawi; Peter J Barnes; Kazuhiro Ito; Ian M Adcock; Paul A Kirkham; Alberto Papi
Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.
American journal of respiratory and critical care medicine 2009;179(7):542-8.
2009: Caterina Brindicci; Kazuhiro Ito; Olga Torre; Peter J Barnes; Sergei A Kharitonov
Effects of aminoguanidine, an inhibitor of inducible nitric oxide synthase, on nitric oxide production and its metabolites in healthy control subjects, healthy smokers, and COPD patients.
Chest 2009;135(2):353-67.
2009: Kazuhiro Ito; Peter J Barnes
COPD as a disease of accelerated lung aging.
Chest 2009;135(1):173-80.
2008: Karine Enesa; Kazuhiro Ito; Le A Luong; Ingvild Thorbjornsen; Chee Phua; Yasuo To; Jonathan Dean; Dorian O Haskard; Joseph Boyle; Ian M Adcock; Paul C Evans
Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms.
The Journal of biological chemistry 2008;283(27):18582-90.
2007: Ian M Adcock; Loukia Tsaprouni; Pankaj Bhavsar; Kazuhiro Ito
Epigenetic regulation of airway inflammation.
Current opinion in immunology 2007;19(6):694-700.
2007: Kazuhiro Ito; Catherine E Charron; Ian M Adcock
Impact of protein acetylation in inflammatory lung diseases.
Pharmacology & therapeutics 2007;116(2):249-65.
2007: Loukia Tsaprouni; Kazuhiro Ito; Ian M Adcock; Neville A Punchard
Suppression of lipopolysaccharide- and tumour necrosis factor-alpha-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation.
Clinical and experimental immunology 2007;150(1):151-7.
2007: Caterina Brindicci; Kazuhiro Ito; Peter J Barnes; Sergei A Kharitonov
Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers.
Chest 2007;132(2):581-8.
2007: Caterina Brindicci; Kazuhiro Ito; Peter J Barnes; Sergei A Kharitonov
Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity.
Chest 2007;131(5):1353-62.
2007: Kazuhiro Ito
Impact of post-translational modifications of proteins on the inflammatory process.
Biochemical Society transactions 2007;35(Pt 2):281-3.
2007: Kazuhiro Ito; Gaetano Caramori; Ian M Adcock
Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease.
The Journal of pharmacology and experimental therapeutics 2007;321(1):1-8.
2007: Kittipong Maneechotesuwan; Yao Xin; Kazuhiro Ito; Elen Jazrawi; Kang-Yun Lee; Omar S Usmani; Peter J Barnes; Ian M Adcock
Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2491-8.
2006: Silvana Morello; Kazuhiro Ito; Satoshi Yamamura; Kang-Yun Lee; Elen Jazrawi; Patricia Desouza; Peter J Barnes; Carla Cicala; Ian M Adcock
IL-1 beta and TNF-alpha regulation of the adenosine receptor (A2A) expression: differential requirement for NF-kappa B binding to the proximal promoter.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7173-83.
2006: Ian M Adcock; Gaetano Caramori; Kazuhiro Ito
New insights into the molecular mechanisms of corticosteroids actions.
Current drug targets 2006;7(6):649-60.
2006: H Bayram; Kazuhiro Ito; Razao Issa; M Ito; Maria B Sukkar; K Fan Chung
Regulation of human lung epithelial cell numbers by diesel exhaust particles.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(4):705-13.
2006: Ian M Adcock; K Fan Chung; Gaetano Caramori; Kazuhiro Ito
Kinase inhibitors and airway inflammation.
European journal of pharmacology 2006;533(1-3):118-32.
2006: Kazuhiro Ito; K Fian Chung; Ian M Adcock
Update on glucocorticoid action and resistance.
The Journal of allergy and clinical immunology 2006;117(3):522-43.
2006: Kazuhiro Ito; Satoshi Yamamura; Sarah Essilfie-Quaye; Borja Cosio; Misako Ito; Peter J Barnes; Ian M Adcock
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression.
The Journal of experimental medicine 2006;203(1):7-13.
2006: Kazuhiro Ito; Stephen J Getting; Catherine E Charron
Mode of glucocorticoid actions in airway disease.
TheScientificWorldJournal 2006;6():1750-69.
2006: Ian M Adcock; Paul Ford; Kazuhiro Ito; Peter J Barnes
Epigenetics and airways disease.
Respiratory research 2006;7():21.
2006: Kang-Yun Lee; Kazuhiro Ito; Ryuji Hayashi; Elen Jazrawi; Peter J Barnes; Ian M Adcock
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):603-15.
2005: Ian M Adcock; Kazuhiro Ito; Peter J Barnes
Histone deacetylation: an important mechanism in inflammatory lung diseases.
COPD 2005;2(4):445-55.
2005: Matthew J Walters; Mark Paul-Clark; Shaun K McMaster; Kazuhiro Ito; Ian M Adcock; Jane A Mitchell
Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance.
Molecular pharmacology 2005;68(5):1343-53.
2005: Omar S Usmani; Kazuhiro Ito; Kittipong Maneechotesuwan; Misako Ito; Malcolm Johnson; Peter J Barnes; Ian M Adcock
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy.
American journal of respiratory and critical care medicine 2005;172(6):704-12.
2005: Caterina Brindicci; Kazuhiro Ito; Onofrio Resta; Neil B Pride; Peter J Barnes; Sergei A Kharitonov
Exhaled nitric oxide from lung periphery is increased in COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;26(1):52-9.
2005: Hiroo Wada; Masahiko Kagoshima; Kazuhiro Ito; Peter J Barnes; Ian M Adcock
5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene.
Biochemical and biophysical research communications 2005;331(1):93-9.
2005: Kazuhiro Ito; Misako Ito; W Mark Elliott; Borja Cosio; Gaetano Caramori; Onn Min Kon; Adam Barczyk; Shizu Hayashi; Ian M Adcock; James C Hogg; Peter J Barnes
Decreased histone deacetylase activity in chronic obstructive pulmonary disease.
The New England journal of medicine 2005;352(19):1967-76.
2005: Peter J Barnes; Ian M Adcock; Kazuhiro Ito
Histone acetylation and deacetylation: importance in inflammatory lung diseases.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(3):552-63.
2005: Ian M Adcock; Kazuhiro Ito
Glucocorticoid pathways in chronic obstructive pulmonary disease therapy.
Proceedings of the American Thoracic Society 2005;2(4):313-9; discussion 340-1.
2005: Ian M Adcock; Borja Cosio; Loukia Tsaprouni; Peter J Barnes; Kazuhiro Ito
Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response.
Antioxidants & redox signaling 2005;7(1-2):144-52.
2004: Gaetano Caramori; Ian M Adcock; Kazuhiro Ito
Anti-inflammatory inhibitors of IkappaB kinase in asthma and COPD.
Current opinion in investigational drugs (London, England : 2000) 2004;5(11):1141-7.
2004: Ryuji Hayashi; Hiroo Wada; Kazuhiro Ito; Ian M Adcock
Effects of glucocorticoids on gene transcription.
European journal of pharmacology 2004;500(1-3):51-62.
2004: Louise E Donnelly; Robert Newton; Gina E Kennedy; Peter S Fenwick; Rachel H F Leung; Kazuhiro Ito; Richard E K Russell; Peter J Barnes
Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L774-83.
2004: Borja Cosio; Loukia Tsaprouni; Kazuhiro Ito; Elen Jazrawi; Ian M Adcock; Peter J Barnes
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.
The Journal of experimental medicine 2004;200(5):689-95.
2004: Borja G Cosío; Buphinder Mann; Kazuhiro Ito; Elen Jazrawi; Peter J Barnes; K Fan Chung; Ian M Adcock
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma.
American journal of respiratory and critical care medicine 2004;170(2):141-7.
2004: John G Matthews; Kazuhiro Ito; Peter J Barnes; Ian M Adcock
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients.
The Journal of allergy and clinical immunology 2004;113(6):1100-8.
2004: Ian M Adcock; Kazuhiro Ito
Steroid resistance in asthma: a major problem requiring novel solutions or a non-issue?
Current opinion in pharmacology 2004;4(3):257-62.
2004: Matthew C Catley; Lisa M Cambridge; Yasuyuki Nasuhara; Kazuhiro Ito; Joanna E Chivers; Andrew Beaton; Neil S Holden; Martin W Bergmann; Peter J Barnes; Robert Newton
Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding.
The Journal of biological chemistry 2004;279(18):18457-66.
2004: Andrea Koch; Mark Giembycz; Kazuhiro Ito; Sam Lim; Elen Jazrawi; Peter J Barnes; Ian M Adcock; Erland Erdmann; K Fan Chung
Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.
American journal of respiratory cell and molecular biology 2004;30(3):342-9.
2004: Peter J Barnes; Kazuhiro Ito; Ian M Adcock
Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.
Lancet 2004;363(9410):731-3.
2004: Kazuhiro Ito; Toyoyuki Hanazawa; Katsuyuki Tomita; Peter J Barnes; Ian M Adcock
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration.
Biochemical and biophysical research communications 2004;315(1):240-5.
2003: Masahiko Kagoshima; Kazuhiro Ito; Borja Cosio; Ian M Adcock
Glucocorticoid suppression of nuclear factor-kappa B: a role for histone modifications.
Biochemical Society transactions 2003;31(Pt 1):60-5.
2002: Loukia Tsaprouni; Kazuhiro Ito; Neville A Punchard; Ian M Adcock
Triamcinolone acetonide and dexamethasome suppress TNF-alpha-induced histone H4 acetylation on lysine residues 8 and 12 in mononuclear cells.
Annals of the New York Academy of Sciences 2002;973():481-3.
2002: Katsuyuki Tomita; Gaetano Caramori; Sam Lim; Kazuhiro Ito; Toyoyuki Hanazawa; Timothy Oates; Irena Chiselita; Elen Jazrawi; K Fan Chung; Peter J Barnes; Ian M Adcock
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers.
American journal of respiratory and critical care medicine 2002;166(5):724-31.
2002: Kazuhiro Ito; Gaetano Caramori; Sam Lim; Timothy Oates; K Fan Chung; Peter J Barnes; Ian M Adcock
Expression and activity of histone deacetylases in human asthmatic airways.
American journal of respiratory and critical care medicine 2002;166(3):392-6.
2002: Kazuhiro Ito; Sam Lim; Gaetano Caramori; Borja Cosio; K Fan Chung; Ian M Adcock; Peter J Barnes
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8921-6.
2002: Kazuhiro Ito; Ian M Adcock
Histone acetylation and histone deacetylation.
Molecular biotechnology 2002;20(1):99-106.
2001: Masahiko Kagoshima; T Wilcke; Kazuhiro Ito; Loukia Tsaprouni; Peter J Barnes; Neville A Punchard; Ian M Adcock
Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation.
European journal of pharmacology 2001;429(1-3):327-34.
2001: Gaetano Caramori; Sam Lim; Kazuhiro Ito; Katsuyuki Tomita; Timothy Oates; Elen Jazrawi; K Fan Chung; Peter J Barnes; Ian M Adcock
Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(3):466-73.
2001: Kazuhiro Ito; Elen Jazrawi; Borja Cosio; Peter J Barnes; Ian M Adcock
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex.
The Journal of biological chemistry 2001;276(32):30208-15.
2001: Kazuhiro Ito; Sam Lim; Gaetano Caramori; K Fan Chung; Peter J Barnes; Ian M Adcock
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1110-2.
2000: koremu meja; Paul M Seldon; Yasuyuki Nasuhara; Kazuhiro Ito; Peter J Barnes; Mark A Lindsay; Mark A Giembycz
p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism.
British journal of pharmacology 2000;131(6):1143-53.
2000: Kazuhiro Ito; Peter J Barnes; Ian M Adcock
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Molecular and cellular biology 2000;20(18):6891-903.
2000: Kazuhiro Ito; P J Barnes; I M Adcock
Histone acetylation and deacetylation.
Methods in molecular medicine 2000;44():309-19.