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Michel Awwad
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54
Cooper, David
47
Sachs, David
18
White-Scharf, Mary
17
Yamada, Kazuhiko
17
Bühler, Leo
17
Alwayn, Ian
13
Basker, MR
12
Down, Julian
12
Gojo, Satoshi
12
Buhler, Leo
12
Schuurman, Henk-Jan
12
Sykes, Megan
12
Robson, Simon
11
Treter, Sarah
11
Thall, Aron
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All Publications
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2009: Knosalla C; Yazawa K; Behdad A; Bodyak N; Shang H; Bühler L; Houser S; Gollackner B; Griesemer A; Schmitt-Knosalla I; Schuurman H-J; Awwad M; Sachs D H; Cooper D K C; Yamada K; Usheva A; Robson S C
Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(5):1006-16.
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2006: Xu Yuanxin; Yang Yong-Guang; Ohdan Hideki; Ryan David; Harper David; Wu Cecelia; Kruger-Grey Huw S; Thall Aron D; Awwad Michel; Sykes Megan
Characterization of anti-Gal antibody-producing cells of baboons and humans.
Transplantation 2006;81(6):940-8.
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2005: Yamamoto Shin; Lavelle John M; Vagefi Parsia A; Arakawa Hitoshi; Samelson-Jones Emma; Moran Shannon; Teranishi Katsuhito; Kamano Chisako; Fishman Jay; Awwad Michel; Neville David M; Shimizu Akira; Sykes Megan; Sachs David H; Yamada Kazuhiko
Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution.
Transplantation 2005;80(12):1783-90.
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2005: Tseng Yau-Lin; Kuwaki Kenji; Dor Frank J M F; Shimizu Akira; Houser Stuart; Hisashi Yosuke; Yamada Kazuhiko; Robson Simon C; Awwad Michel; Schuurman Henk-Jan; Sachs David H; Cooper David K C
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months.
Transplantation 2005;80(10):1493-500.
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2005: Dor F J M F; Kuwaki K; Tseng Y-L; Shimizu A; Houser S L; Yamada K; Hawley R J; Patience C; Awwad M; Fishman J A; Robson S C; Sachs D H; Schuurman H-J; Cooper D K C
Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons.
Transplantation proceedings 2005;37(1):489-90.
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2005: Kuwaki Kenji; Tseng Yau-Lin; Dor Frank J M F; Shimizu Akira; Houser Stuart L; Sanderson Todd M; Lancos Courtney J; Prabharasuth Derek D; Cheng Jane; Moran Kathleen; Hisashi Yosuke; Mueller Nicolas; Yamada Kazuhiko; Greenstein Julia L; Hawley Robert J; Patience Clive; Awwad Michel; Fishman Jay A; Robson Simon C; Schuurman Henk-Jan; Sachs David H; Cooper David K C
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience.
Nature medicine 2005;11(1):29-31.
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2005: Yamada Kazuhiko; Yazawa Koji; Shimizu Akira; Iwanaga Takehiro; Hisashi Yosuke; Nuhn Matthew; O'Malley Patricia; Nobori Shuji; Vagefi Parsia A; Patience Clive; Fishman Jay; Cooper David K C; Hawley Robert J; Greenstein Julia; Schuurman Henk-Jan; Awwad Michel; Sykes Megan; Sachs David H
Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue.
Nature medicine 2005;11(1):32-4.
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2004: Dor Frank J M F; Tseng Yau-Lin; Cheng Jane; Moran Kathleen; Sanderson Todd M; Lancos Courtney J; Shimizu Akira; Yamada Kazuhiko; Awwad Michel; Sachs David H; Hawley Robert J; Schuurman Henk-Jan; Cooper David K C
alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies.
Transplantation 2004;78(1):15-20.
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2004: Tseng Y-L; Dor F J M F; Kuwaki K; Ryan D; Wood J; Denaro M; Giovino M; Yamada K; Hawley R; Patience C; Schuurman H-J; Awwad M; Sachs D H; Cooper D K C
Bone marrow transplantation from alpha1,3-galactosyltransferase gene-knockout pigs in baboons.
Xenotransplantation 2004;11(4):361-70.
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2004: Knosalla C; Ryan D J J; Moran K; Gollackner B; Schuler W; Sachs D H; Awwad M; Schuurman H-J; Cooper D K C
Initial experience with the human anti-human CD154 monoclonal antibody, ABI793, in pig-to-baboon xenotransplantation.
Xenotransplantation 2004;11(4):353-60.
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2004: Gollackner Bernd; Goh Seo Kiat; Qawi Imrana; Buhler Leo; Knosalla Christoph; Daniel Soizic; Kaczmarek Elzbieta; Awwad Michel; Cooper David K C; Robson Simon C
Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity.
Transplantation 2004;77(11):1735-41.
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2004: Kuwaki K; Knosalla C; Moran K; Alt A; Katopodis A G; Duthaler R O; Schuurman H-J; Awwad M; Cooper D K C
Reduction of anti-Galalpha1,3Gal antibodies by infusion of types 2 and 6 gal trisaccharides conjugated to poly-L-lysine.
Xenotransplantation 2004;11(2):210-5.
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2004: Kuwaki Kenji; Knosalla Christoph; Dor Frank J M F; Gollackner Bernd; Tseng Yau-Lin; Houser Stuart; Mueller Nicolas; Prabharasuth Derek; Alt Amy; Moran Kathy; Cheng Jane; Behdad Amir; Sachs David H; Fishman Jay A; Schuurman Henk-Jan; Awwad Michel; Cooper David K C
Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(3):363-72.
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2004: Harper D; Gollackner B; Xu Y; Calderhead D; Ryan D; Li W; Cheng J; Wu C; Moran K; Latinne D; Bazin H; White-Scharf M E; Cooper D K C; Awwad M;
In vitro and in vivo investigation of a novel monoclonal antibody to plasma cells (W5 mAb).
Xenotransplantation 2004;11(1):78-90.
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2004: Eckermann Jan M; Buhler Leo H; Zhu Alex; Dor Frank J M F; Awwad Michel; Cooper David K C
Initial investigation of the potential of modified porcine erythrocytes for transfusion in primates.
Xenotransplantation 2004;11(1):18-26.
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2003: Knosalla Christoph; Gollackner Bernd; Bühler Leo; Mueller Nicolas J; Houser Stuart; Mauiyyedi Shamila; Sachs David H; Robson Simon C; Fishman Jay; Schuurman Henk-Jan; Awwad Michel; Cooper David K C
Correlation of biochemical and hematological changes with graft failure following pig heart and kidney transplantation in baboons.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(12):1510-9.
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2003: Gollackner Bernd; Knosalla Christoph; Houser Stuart; Mauiyyedi Shamila; Buhler Leo; Kawai Tatsuo; Duggan Mike; Sachs David H; Awwad Michel; Cooper David K C
Pig kidney transplantation in baboons treated intravenously with a bovine serum albumin-Galalpha1-3Gal conjugate.
Xenotransplantation 2003;10(6):606-14.
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2003: Teranishi Katsuhito; Alwayn Ian P J; Bühler Leo; Gollackner Bernd; Knosalla Christoph; Huck Jennifer; Duthaler Rudolf; Katopodis Andreas; Sachs David H; Schuurman Henk-Jan; Awwad Michel; Cooper David K C
Depletion of anti-Gal antibodies by the intravenous infusion of Gal type 2 and 6 glycoconjugates in baboons.
Xenotransplantation 2003;10(4):357-67.
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2003: Gollackner Bernd; Mueller Nicolas J; Houser Stuart; Qawi Imrana; Soizic Daniel; Knosalla Christoph; Buhler Leo; Dor Frank J M F; Awwad Michel; Sachs David H; Cooper David K C; Robson Simon C; Fishman Jay A
Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation.
Transplantation 2003;75(11):1841-7.
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2003: Barth Rolf N; Yamamoto Shin; LaMattina John C; Kumagai Naoki; Kitamura Hiroshi; Vagefi Parsia A; Awwad Michel; Colvin Robert B; Cooper David K C; Sykes Megan; Sachs David H; Yamada Kazuhiko
Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness.
Transplantation 2003;75(10):1615-24.
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2003: Wu Anette; Yamada Kazuhiko; Neville David M; Awwad Michel; Wain John C; Shimizu Akira; Gojo Satoshi; Kitamura Hiroshi; Colvin Robert B; Cooper David K C; Sykes Megan; Sachs David H
Xenogeneic thymus transplantation in a pig-to-baboon model.
Transplantation 2003;75(3):282-91.
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2002: Teranishi K; Alwayn I P J; Bühler L; Gollackner B; Knosalla C; Correa L; Down J D; White-Scharf M E; Sachs D H; Duthaler R; Katopodis A; Awwad M; Cooper D K C
Depletion of natural anti-pig antibodies by the continuous infusion of oligosaccharides in a pig-to-baboon model.
Transplantation proceedings 2002;34(7):2757-8.
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2002: Bühler Leo; Kurilla-Mahon Barbara; Chang Qing; Abraham Sonny; Alwayn Ian P J; Appel James Z; Newman Dawne; Awwad Michel; White-Scharf Mary E; Sackstein Roberto; Sachs David H; Cooper David K C; Down Julian D
Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells.
Transplantation 2002;74(8):1159-66.
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2002: Gojo S; Harper D; Down J; Awwad M; Cooper D K C
Differential expression of Galalpha1,3Gal epitopes on fetal and adult porcine hematopoietic cells.
Xenotransplantation 2002;9(4):297-300.
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2002: Appel James Z; Newman Dawn; Awwad Michel; Kruger Gray Huw S; Down Julian; Cooper David K C; Robson Simon C
Activation of human endothelial cells by mobilized porcine leukocytes in vitro: implications for mixed chimerism in xenotransplantation.
Transplantation 2002;73(8):1302-9.
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2002: Teranishi Katsuhito; Manez Rafael; Awwad Michel; Cooper David K C
Anti-Gal alpha 1-3Gal IgM and IgG antibody levels in sera of humans and old world non-human primates.
Xenotransplantation 2002;9(2):148-54.
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2002: McMorrow Isabel M; Buhler Leo; Treter Sarah; Neethling Francisca A; Alwayn Ian P J; Comrack Christopher A; Kitamura Hiroshi; Awwad Michel; DerSimonian Harout; Cooper David K C; Sachs David H; LeGuern Christian
Modulation of the in vivo primate anti-Gal response through administration of anti-idiotypic antibodies.
Xenotransplantation 2002;9(2):106-14.
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2002: Bühler L; Deng S; O'Neil J; Kitamura H; Koulmanda M; Baldi A; Rahier J; Alwayn I P J; Appel J Z; Awwad M; Sachs D H; Weir G; Squifflet J P; Cooper D K C; Morel Ph
Adult porcine islet transplantation in baboons treated with conventional immunosuppression or a non-myeloablative regimen and CD154 blockade.
Xenotransplantation 2002;9(1):3-13.
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2002: Teranishi K; Gollackner B; Bühler L; Knosalla C; Correa L; Down J D; White-Scharf M E; Sachs D H; Awwad M; Cooper D K C
Depletion of anti-gal antibodies in baboons by intravenous therapy with bovine serum albumin conjugated to gal oligosaccharides.
Transplantation 2002;73(1):129-39.
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2002: Bühler L; Awwad M; Treter S; Chang Q; Basker M; Alwayn I P J; Teranishi K; Ericsson T; Moran K; Harper D; Kurilla-Mahon B; Huang C A; Sackstein R; Sykes M; White-Scharf M E; Sachs D H; Down J D; Cooper D K
Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockade.
Transplantation 2002;73(1):12-22.
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2001: Teranishi K; Treter S; Alwayn I P; Buhler L; Awwad M; Cooper D K
Assessment of methotrexate as a potential immunosuppressive agent in baboons.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001;20(12):1335-9.
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2001: Bühler L; Alwayn I P; Basker M; Oravec G; Thall A; White-Scharf M E; Sachs D H; Awwad M; Cooper D K
CD40-CD154 pathway blockade requires host macrophages to induce humoral unresponsiveness to pig hematopoietic cells in baboons.
Transplantation 2001;72(11):1759-68.
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2001: Bühler L; Yamada K; Kitamura H; Alwayn I P; Basker M; Appel J Z; Colvin R B; White-Scharf M E; Sachs D H; Robson S C; Awwad M; Cooper D K
Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation.
Transplantation 2001;72(11):1743-52.
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2001: Basker M; Alwayn I P; Buhler L; Harper D; Abraham S; Kruger Gray H; DeAngelis H; Awwad M; Down J; Rieben R; White-Scharf M E; Sachs D H; Thall A; Cooper D K
Clearance of mobilized porcine peripheral blood progenitor cells is delayed by depletion of the phagocytic reticuloendothelial system in baboons.
Transplantation 2001;72(7):1278-85.
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2001: Alwayn I P; Xu Y; Basker M; Wu C; Buhler L; Lambrigts D; Treter S; Harper D; Kitamura H; Vitetta E S; Abraham S; Awwad M; White-Scharf M E; Sachs D H; Thall A; Cooper D K
Effects of specific anti-B and/or anti-plasma cell immunotherapy on antibody production in baboons: depletion of CD20- and CD22-positive B cells does not result in significantly decreased production of anti-alphaGal antibody.
Xenotransplantation 2001;8(3):157-71.
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2001: Alwayn I P; Buhler L; Appel J Z; Goepfert C; Csizmadia E; Correa L; Harper D; Kitamura H; Down J; Awwad M; Sackstein R; Cooper D K; Robson S C
Mechanisms of thrombotic microangiopathy following xenogeneic hematopoietic progenitor cell transplantation.
Transplantation 2001;71(11):1601-9.
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2001: Wu A; Yamada K; Awwad M; Kitamura H; Wain J; Neville D M; Cooper D K; Sykes M; Sachs D H
Effects of xenogeneic thymic transplantation in baboons.
Transplantation proceedings 2001;33(1-2):766.
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2001: Bühler L; Yamada K; Alwayn I; Kitamura H; Basker M; Barth R N; Appel J; Awwad M; Thall A; White-Scharf M E; Sachs D H; Cooper D K
Miniature swine and hDAF pig kidney transplantation in baboons treated with a nonmyeloablative regimen and CD154 blockade.
Transplantation proceedings 2001;33(1-2):716.
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2000: Bühler L; Basker M; Alwayn I P; Goepfert C; Kitamura H; Kawai T; Gojo S; Kozlowski T; Ierino F L; Awwad M; Sachs D H; Sackstein R; Robson S C; Cooper D K
Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates.
Transplantation 2000;70(9):1323-31.
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2000: Watts A; Foley A; Awwad M; Treter S; Oravec G; Buhler L; Alwayn I P; Kozlowski T; Lambrigts D; Gojo S; Basker M; White-Scharf M E; Andrews D; Sachs D H; Cooper D K
Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons.
Xenotransplantation 2000;7(3):181-5.
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2000: Bühler L; Treter S; McMorrow I; Neethling F A; Alwayn I; Awwad M; Thall A; Cooper D K; LeGuern C; Sachs D H
Injection of porcine anti-idiotypic antibodies to primate anti-Gal antibodies leads to active inhibition of serum cytotoxicity in a baboon.
Transplantation proceedings 2000;32(5):1102.
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2000: Bühler L; Awwad M; Treter S; Basker M; Ericson T; Lachance A; Oldmixon B; Kurilla-Mahon B; Gojo S; Huang C; Thall A; Down J D; White-Scharf M E; Sachs D H; Cooper D K
Induction of mixed hematopoietic chimerism in the pig-to-baboon model.
Transplantation proceedings 2000;32(5):1101.
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2000: Bühler L; Awwad M; Basker M; Gojo S; Thall A; Down J D; Sykes M; Andrews D; Sackstein R; White-Scharf M E; Sachs D H; Cooper D K
A nonmyeloablative regimen with CD40L blockade leads to humoral and cellular hyporesponsiveness to pig hematopoietic cells in baboons.
Transplantation proceedings 2000;32(5):1100.
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2000: Wu A; Yamada K; Awwad M; Shimizu A; Watts A; Murphy M; Gojo S; Neville D; Cooper D K; Sykes M; Sachs D H
Experience with porcine thymic transplantation in baboons.
Transplantation proceedings 2000;32(5):1048.
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2000: Down J D; Awwad M; Kurilla-Mahon B; Moran K; Ericsson T; Oldmixon B; Lachance A; Watts A; Treter S; Nash K; Gojo S; Sachs D H; White-Scharf M E; Cooper D K
Increases in autologous hematopoietic progenitors in the blood of baboons following irradiation and treatment with porcine stem cell factor and interleukin-3.
Transplantation proceedings 2000;32(5):1045-6.
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2000: Basker M; Alwayn I P; Treter S; Harper D; Buhler L; Andrews D; Thall A; Lambrigts D; Awwad M; White-Scharf M; Sachs D H; Cooper D K
Effect of B cell/plasma cell depletion or suppression on anti-Gal antibody in the baboon.
Transplantation proceedings 2000;32(5):1009.
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2000: Watts A; Foley A; Awwad M; Treter S; Lambrigts D; Buhler L; Gojo S; Basker M; Oravec G; Sachs D H; Andrews D; Cooper D K
Plasma perfusion by apheresis through a gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 275 aphereses in baboons.
Transplantation proceedings 2000;32(5):860.
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2000: Bühler L; Awwad M; Basker M; Gojo S; Watts A; Treter S; Nash K; Oravec G; Chang Q; Thall A; Down J D; Sykes M; Andrews D; Sackstein R; White-Scharf M E; Sachs D H; Cooper D K
High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response.
Transplantation 2000;69(11):2296-304.
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2000: Gojo S; Bartholomew A; Xu Y; Neethling F A; Awwad M; Saidman S; Cosimi A B; Cooper D K
Anti-Galalpha1-3Gal antibody levels in organ transplant recipients receiving immunosuppressive therapy.
Transplantation 2000;69(5):914-7.
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2000: Yang Y G; Chen A M; Garrett L J; Sergio J J; Theodore P; Awwad M; VerHalen J; Bodine D M; Sachs D H; Sykes M
Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier.
Xenotransplantation 2000;7(1):58-64.
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1999: Bühler L; Pidwell D; Dowling R D; Newman D; Awwad M; Cooper D K
Different responses of human anti-HLA and anti-alphagal antibody to long-term intravenous immunoglobulin therapy.
Xenotransplantation 1999;6(3):181-6.
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1999: Ierino F L; Gojo S; Banerjee P T; Giovino M; Xu Y; Gere J; Kaynor C; Awwad M; Monroy R; Rembert J; Hatch T; Foley A; Kozlowski T; Yamada K; Neethling F A; Fishman J; Bailin M; Spitzer T R; Cooper D K; Cosimi A B; LeGuern C; Sachs D H
Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogeneic barriers.
Transplantation 1999;67(8):1119-28.
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1999: Wu A; Esnaola N F; Yamada K; Awwad M; Shimizu A; Huang C; Wain J; Zhao Y; Neville D M; Cooper D K; Sykes M; Sachs D H
Xenogeneic thymic transplantation in a pig-to-nonhuman primate model.
Transplantation proceedings 1999;31(1-2):957.
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1999: Kozlowski T; Shimizu A; Lambrigts D; Yamada K; Fuchimoto Y; Glaser R; Monroy R; Xu Y; Awwad M; Colvin R B; Cosimi A B; Robson S C; Fishman J; Spitzer T R; Cooper D K; Sachs D H
Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption.
Transplantation 1999;67(1):18-30.
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1998: Przepiorka D; Phillips G L; Ratanatharathorn V; Cottler-Fox M; Sehn L H; Antin J H; LeBherz D; Awwad M; Hope J; McClain J B
A phase II study of BTI-322, a monoclonal anti-CD2 antibody, for treatment of steroid-resistant acute graft-versus-host disease.
Blood 1998;92(11):4066-71.
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1998: Lambrigts D; Van Calster P; Xu Y; Awwad M; Neethling F A; Kozlowski T; Foley A; Watts A; Chae S J; Fishman J; Thall A D; White-Scharf M E; Sachs D H; Cooper D K
Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-alphaGal antibody in the baboon.
Xenotransplantation 1998;5(4):274-83.
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1998: Kozlowski T; Monroy R; Xu Y; Glaser R; Awwad M; Cooper D K; Sachs D H
Anti-Gal(alpha)1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction.
Transplantation 1998;66(2):176-82.
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1998: Kozlowski T; Ierino F L; Lambrigts D; Foley A; Andrews D; Awwad M; Monroy R; Cosimi A B; Cooper D K; Sachs D H
Depletion of anti-Gal(alpha)1-3Gal antibody in baboons by specific alpha-Gal immunoaffinity columns.
Xenotransplantation 1998;5(2):122-31.
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1998: Xu Y; Lorf T; Sablinski T; Gianello P; Bailin M; Monroy R; Kozlowski T; Awwad M; Cooper D K; Sachs D H
Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column.
Transplantation 1998;65(2):172-9.
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1997: Besse T; Malaise J; Mourad M; Pirson Y; Hope J; Awwad M; White-Scharf M; Squifflet J P
Prevention of rejection with BTI-322 after renal transplantation (results at 9 months).
Transplantation proceedings 1997;29(5):2425-6.
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1997: Kozlowski T; Fuchimoto Y; Monroy R; Bailin M; Martinez-Ruiz R; Foley A; Xu Y; Awwad M; Fishman J; Andrews D; Ritzenthaler J; Sablinski T; Ierino F L; Sachs D H
Apheresis and column absorption for specific removal of Gal-alpha-1,3 Gal natural antibodies in a pig-to-baboon model.
Transplantation proceedings 1997;29(1-2):961.
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