FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Nobuyuki Ito

Research Profile

Living Beings

Chemicals & Drugs

Disorders

Concepts & Ideas

Co-author Network

Publications

TOP 3
Hiroyuki Tsuda; Mitsuru Futakuchi; Katsumi Fukamachi; Tomoyuki Shirai; Katsumi Imaida; Shoji Fukushima; Masae Tatematsu; Fumio Furukawa; Seiko Tamano; Nobuyuki Ito
A medium-term, rapid rat bioassay model for the detection of carcinogenic potential of chemicals.
Nobuyuki Ito; Seiko Tamano; Tomoyuki Shirai
A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals.
Nobuyuki Ito
Genetically modified foods: hazard identification and risk assessment. Session summary.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Nobuyuki Ito (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Hiroyuki Tsuda; Mitsuru Futakuchi; Katsumi Fukamachi; Tomoyuki Shirai; Katsumi Imaida; Shoji Fukushima; Masae Tatematsu; Fumio Furukawa; Seiko Tamano; Nobuyuki Ito
A medium-term, rapid rat bioassay model for the detection of carcinogenic potential of chemicals.
Toxicologic pathology 2010;38(1):182-7.
2003: Nobuyuki Ito; Seiko Tamano; Tomoyuki Shirai
A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals.
Cancer science 2003;94(1):3-8.
2002: Nobuyuki Ito
Genetically modified foods: hazard identification and risk assessment. Session summary.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2002;54(1):57-9.
2000: Nobuyuki Ito; Katsumi Imaida; Makoto Asamoto; Tomoyuki Shirai
Early detection of carcinogenic substances and modifiers in rats.
Mutation research 2000;462(2-3):209-17.
2000: Katsumi Imaida; Kumiko Ogawa; Satoru Takahashi; T Ito; Tsuyoshi Yamaguchi; Y Totsuka; K Wakabayashi; K Tanaka; Nobuyuki Ito; Tomoyuki Shirai
Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl-imidazo [4,5-b] pyridine (PhIP).
Cancer letters 2000;150(1):63-9.
1999: Tomoyuki Shirai; L Cui; Satoru Takahashi; Mitsuru Futakuchi; Makoto Asamoto; Koji Kato; Nobuyuki Ito
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in the rat prostate and induction of invasive carcinomas by subsequent treatment with testosterone propionate.
Cancer letters 1999;143(2):217-21.
1999: Masashi Sano; A Hagiwara; Seiko Tamano; R Hasegawa; Katsumi Imaida; Nobuyuki Ito; Tomoyuki Shirai
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.
The Journal of toxicological sciences 1999;24(3):177-86.
1999: Tomoyuki Shirai; Masao Hirose; Nobuyuki Ito
Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals.
IARC scientific publications 1999;(146):251-72.
1998: Tomoyuki Shirai; Satoru Takahashi; L Cui; Y Yamada; M Tada; F F Kadlubar; Nobuyuki Ito
Use of polyclonal antibodies against carcinogen-DNA adducts in analysis of carcinogenesis.
Toxicology letters 1998;102-103():441-6.
1998: Nobuyuki Ito; Katsumi Imaida; Masao Hirose; Tomoyuki Shirai
Medium-term bioassays for carcinogenicity of chemical mixtures.
Environmental health perspectives 1998;106 Suppl 6():1331-6.
1998: Katsumi Imaida; Masao Taki; So-ichi Watanabe; Yoshitsugu Kamimura; T Ito; Tsuyoshi Yamaguchi; Nobuyuki Ito; Tomoyuki Shirai
The 1.5 GHz electromagnetic near-field used for cellular phones does not promote rat liver carcinogenesis in a medium-term liver bioassay.
Japanese journal of cancer research : Gann 1998;89(10):995-1002.
1998: Nobuyuki Ito; Katsumi Imaida; Seiko Tamano; A Hagiwara; Tomoyuki Shirai
Medium-term bioassays as alternative carcinogenicity test.
The Journal of toxicological sciences 1998;23 Suppl 2():103-6.
1998: Katsumi Imaida; Masao Taki; Tsuyoshi Yamaguchi; T Ito; So-ichi Watanabe; Kanako Wake; A Aimoto; Yoshitsugu Kamimura; Nobuyuki Ito; Tomoyuki Shirai
Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay.
Carcinogenesis 1998;19(2):311-4.
1998: R Hasegawa; Mitsuru Futakuchi; Yasumoto Mizoguchi; Tsuyoshi Yamaguchi; Tomoyuki Shirai; Nobuyuki Ito; W Lijinsky
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds.
Cancer letters 1998;123(2):185-91.
1997: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; Seiko Tamano; A Hagiwara; Masao Hirose; Tomoyuki Shirai
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Mutation research 1997;376(1-2):107-14.
1997: Mayumi Kawabe; M A Shibata; Masashi Sano; Y Takesada; Seiko Tamano; Nobuyuki Ito; Tomoyuki Shirai
Decrease of prostaglandin E2 and 5-bromo-2'-deoxyuridine labeling but not prostate tumor development by indomethacin treatment of rats given 3,2'-dimethyl-4-aminobiphenyl and testosterone propionate.
Japanese journal of cancer research : Gann 1997;88(4):350-5.
1997: K Takaba; Masao Hirose; Y Yoshida; J Kimura; Nobuyuki Ito; Tomoyuki Shirai
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.
Cancer letters 1997;113(1-2):39-46.
1996: R Hasegawa; T Kato; Masao Hirose; Satoru Takahashi; Tomoyuki Shirai; Nobuyuki Ito
Enhancement of hepatocarcinogenesis by combined administration of food-derived heterocyclic amines at low doses in the rat.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(11-12):1097-101.
1996: Nobuyuki Ito; A Hagiwara; Seiko Tamano; M Futacuchi; Katsumi Imaida; Tomoyuki Shirai
Effects of pesticide mixtures at the acceptable daily intake levels on rat carcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(11-12):1091-6.
1996: R Hasegawa; I Yoshimura; Katsumi Imaida; Nobuyuki Ito; Tomoyuki Shirai
Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat.
Japanese journal of cancer research : Gann 1996;87(11):1125-33.
1996: Katsumi Imaida; A Hagiwara; H Yada; T Masui; R Hasegawa; Masao Hirose; T Sugimura; Nobuyuki Ito; Tomoyuki Shirai
Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine.
Japanese journal of cancer research : Gann 1996;87(11):1116-20.
1996: Mitsuru Futakuchi; W Lijinsky; R Hasegawa; Masao Hirose; Nobuyuki Ito; Tomoyuki Shirai
Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat.
Cancer letters 1996;106(2):263-9.
1996: W Thamavit; Danai Tiwawech; Malcolm Moore; Nobuyuki Ito; Tomoyuki Shirai
Equivocal evidence of complete carcinogenicity after repeated infection of Syrian hamsters with Opisthorchis viverrini.
Toxicologic pathology 1996;24(4):493-7.
1996: Mitsuru Futakuchi; R Hasegawa; A Yamamoto; L Cui; Tadashi Ogiso; Nobuyuki Ito; Tomoyuki Shirai
Low susceptibility of the spontaneously hypertensive rat (SHR) to quinoline-induction of hepatic hemangioendothelial sarcomas.
Cancer letters 1996;104(1):37-41.
1996: T Mori; L Cui; Koji Kato; Satoru Takahashi; Katsumi Imaida; S Iwasaki; Nobuyuki Ito; Tomoyuki Shirai
Direct effects of testosterone, dihydrotestosterone and estrogen on 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in castrated F344 rats.
Japanese journal of cancer research : Gann 1996;87(6):570-4.
1996: Satoru Takahashi; K Imaida; Tomoyuki Shirai; K Wakabayashi; M Nagao; T Sugimura; Nobuyuki Ito
Chronic administration of the mutagenic heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine induces cardiac damage with characteristic mitochondrial changes in Fischer rats.
Toxicologic pathology 1996;24(3):273-7.
1996: Masashi Sano; E Miyata; Seiko Tamano; A Hagiwara; Nobuyuki Ito; Tomoyuki Shirai
Lack of carcinogenicity of tamarind seed polysaccharide in B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(5):463-7.
1996: Mayumi Kawabe; Y Takesada; Seiko Tamano; A Hagiwara; Nobuyuki Ito; Tomoyuki Shirai
Subchronic toxicity study of L-isoleucine in F344 rats.
Journal of toxicology and environmental health 1996;47(5):499-508.
1996: J Kimura; R Hasegawa; M Yaono; T Kato; K Wakabayashi; T Sugimura; Nobuyuki Ito; Tomoyuki Shirai
Inhibitory potential of pregnancy and lactation on mammary carcinogenesis induced by a food-derived carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in Sprague-Dawley rats.
Cancer letters 1996;101(1):73-8.
1996: S Wada; T Kato; M Mutai; K Ozaki; S Yamaguchi; Dae Joong Kim; H Baba-Toriyama; Makoto Asamoto; Nobuyuki Ito; Hiroyuki Tsuda
Modifying influence of swine-serum-induced liver fibrosis on development of preneoplastic lesions in rat liver.
Japanese journal of cancer research : Gann 1996;87(3):240-6.
1996: R Cabral; Toru Hoshiya; K Hakoi; R Hasegawa; Nobuyuki Ito
Medium-term bioassay for the hepatocarcinogenicity of hexachlorobenzene.
Cancer letters 1996;100(1-2):223-6.
1996: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; Masao Hirose; Tomoyuki Shirai
Medium-term liver and multi-organ carcinogenesis bioassays for carcinogens and chemopreventive agents.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(2-3):113-9.
1996: Kumiko Ogawa; Katsumi Imaida; T Masui; Mayumi Kawabe; R Hasegawa; K Kato; Nobuyuki Ito; Tomoyuki Shirai
Chemically induced lung and forestomach neoplasias in transgenic mice carry mutant forms of the human c-Ha-ras transgene.
Carcinogenesis 1996;17(2):341-5.
1996: T Kato; R Hasegawa; D Nakae; Masao Hirose; M Yaono; L Cui; Y Kobayashi; Y Konishi; Nobuyuki Ito; Tomoyuki Shirai
Dose-dependent induction of 8-hydroxyguanine and preneoplastic foci in rat liver by a food-derived carcinogen, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, at low dose levels.
Japanese journal of cancer research : Gann 1996;87(2):127-33.
1996: A Hagiwara; Y Kokubo; Y Takesada; Harunari Tanaka; Seiko Tamano; Masao Hirose; Tomoyuki Shirai; Nobuyuki Ito
Inhibitory effects of phenolic compounds on development of naturally occurring preneoplastic hepatocytic foci in long-term feeding studies using male F344 rats.
Teratogenesis, carcinogenesis, and mutagenesis 1996;16(6):317-25.
1995: Masao Hirose; R Hasegawa; J Kimura; Keisuke Akagi; Y Yoshida; Harunari Tanaka; Tokutaro Miki; T Satoh; K Wakabayashi; Nobuyuki Ito
Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Carcinogenesis 1995;16(12):3049-55.
1995: Nobuyuki Ito; A Hagiwara; Seiko Tamano; R Hasegawa; Katsumi Imaida; Masao Hirose; Tomoyuki Shirai
Lack of carcinogenicity of pesticide mixtures administered in the diet at acceptable daily intake (ADI) dose levels in rats.
Toxicology letters 1995;82-83():513-20.
1995: Tomoyuki Shirai; Satoru Takahashi; T Mori; Katsumi Imaida; Mitsuru Futakuchi; Shuhua Ye; Gail S Prins; Nobuyuki Ito
Immunohistochemically demonstrated androgen receptor expression in the rat prostate during carcinogenesis induced by 3,2'-dimethyl-4-aminobiphenyl with or without testosterone.
Urologic oncology 1995;1(6):263-8.
1995: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; Masao Hirose; Makoto Asamoto; Tomoyuki Shirai
Concepts in multistage carcinogenesis.
Critical reviews in oncology/hematology 1995;21(1-3):105-133.
1995: M Shibata; R Hasegawa; Katsumi Imaida; A Hagiwara; Kumiko Ogawa; Masao Hirose; Nobuyuki Ito; Tomoyuki Shirai
Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model.
Cancer research 1995;55(21):4870-4.
1995: Kumiko Ogawa; Y Shichino; M Tatematsu; C Furihata; Makoto Asamoto; S Nagase; Tomoyuki Shirai; Nobuyuki Ito
Increasing development of pepsinogen-altered pyloric glands and adenocarcinoma in glandular stomach of analbuminemic rats.
Cancer letters 1995;96(2):219-24.
1995: R Hasegawa; Masao Hirose; T Kato; A Hagiwara; P Boonyaphiphat; M Nagao; Nobuyuki Ito; Tomoyuki Shirai
Inhibitory effect of chlorophyllin on PhIP-induced mammary carcinogenesis in female F344 rats.
Carcinogenesis 1995;16(9):2243-6.
1995: Masao Hirose; S Iwata; E Ito; Y Nihro; Satoru Takahashi; Yasumoto Mizoguchi; Tokutaro Miki; T Satoh; Nobuyuki Ito; Tomoyuki Shirai
Strong anti-mutagenic activity of the novel lipophilic antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone against heterocyclic amine-induced mutagenesis in the Ames assay and its effect on metabolic activation of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole (Glu-p-1).
Carcinogenesis 1995;16(9):2227-32.
1995: M Yaono; R Hasegawa; Yasumoto Mizoguchi; Mitsuru Futakuchi; T Nakamura; Nobuyuki Ito; Tomoyuki Shirai
Hepatocyte growth factor enhancement of preneoplastic hepatic foci development in rats treated with diethylnitrosamine and N-ethyl-N-hydroxyethylnitrosamine.
Japanese journal of cancer research : Gann 1995;86(8):718-23.
1995: Keisuke Akagi; Masao Hirose; Toru Hoshiya; Yasumoto Mizoguchi; Nobuyuki Ito; Tomoyuki Shirai
Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model.
Cancer letters 1995;94(1):113-21.
1995: T Masui; Tomoyuki Shirai; Katsumi Imaida; Masao Hirose; Mitsuru Futakuchi; M Tatematsu; Nobuyuki Ito
Ki-ras mutations with frequent normal allele loss versus absence of p53 mutations in rat prostate and seminal vesicle carcinomas induced with 3,2'-dimethyl-4-aminobiphenyl.
Molecular carcinogenesis 1995;13(1):21-6.
1995: Harunari Tanaka; Masao Hirose; A Hagiwara; Katsumi Imaida; Tomoyuki Shirai; Nobuyuki Ito
Rat strain differences in catechol carcinogenicity to the stomach.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(2):93-8.
1995: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; Y Kurata; A Hagiwara; Tomoyuki Shirai
Effect of ingestion of 20 pesticides in combination at acceptable daily intake levels on rat liver carcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(2):159-63.
1995: Masao Hirose; Keisuke Akagi; R Hasegawa; M Yaono; T Satoh; Y Hara; K Wakabayashi; Nobuyuki Ito
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP)-induced mammary gland carcinogenesis by antioxidants in F344 female rats.
Carcinogenesis 1995;16(2):217-21.
1995: T Kato; Tadashi Ogiso; Koji Kato; Masashi Sano; R Hasegawa; Tomoyuki Shirai; Nobuyuki Ito
Lack of promoting activity of four pesticides on induction of preneoplastic liver cell foci in rats.
Teratogenesis, carcinogenesis, and mutagenesis 1995;15(5):251-7.
1995: Nobuyuki Ito; R Hasegawa; E Asakawa; Masao Hirose; Katsumi Imaida; A Hagiwara
Enhancement of rat liver cell foci development by combined treatment with heterocyclic amines at low doses.
Princess Takamatsu symposia 1995;23():251-9.
1995: Tomoyuki Shirai; Seiko Tamano; M Sano; T Masui; R Hasegawa; Nobuyuki Ito
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats: dose-response studies.
Princess Takamatsu symposia 1995;23():232-9.
1995: R Cabral; K Hakoi; Toru Hoshiya; R Hasegawa; Nobuyuki Ito
Lack of carcinogenicity of daminozide, alone or in combination with its contaminant 1,1-dimethylhydrazine, in a medium-term bioassay.
Teratogenesis, carcinogenesis, and mutagenesis 1995;15(6):307-12.
1995: R Hasegawa; Tadashi Ogiso; Katsumi Imaida; Tomoyuki Shirai; Nobuyuki Ito
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(1):15-20.
1994: M A Shibata; Tomoyuki Shirai; Kumiko Ogawa; Satoru Takahashi; C P Wild; R Montesano; Hiroyuki Tsuda; Nobuyuki Ito
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
Carcinogenesis 1994;15(12):2965-8.
1994: R Hasegawa; Harunari Tanaka; Seiko Tamano; Tomoyuki Shirai; M Nagao; T Sugimura; Nobuyuki Ito
Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay.
Carcinogenesis 1994;15(11):2567-73.
1994: Makoto Itoh; Chawalit Pairojkul; W Thamawit; Paiboon Sithithaworn; Danai Tiwawech; T Uttaravicien; Tomoyuki Shirai; Nobuyuki Ito
Association of antibodies to Opisthorchis viverrini with hepatobiliary disease in northeastern Thailand.
The American journal of tropical medicine and hygiene 1994;51(4):424-9.
1994: Tomoyuki Shirai; M Tada; M Kojima; R Hasegawa; T Masui; Nobuyuki Ito
DNA adducts in target and nontarget tissues of 3,2'-dimethyl-4-aminobiphenyl in rats.
Environmental health perspectives 1994;102 Suppl 6():167-72.
1994: Seiko Tamano; R Hasegawa; A Hagiwara; M Nagao; T Sugimura; Nobuyuki Ito
Carcinogenicity of a mutagenic compound from food, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alpha C), in male F344 rats.
Carcinogenesis 1994;15(9):2009-15.
1994: R Hasegawa; T Yoshida; Yasumoto Mizoguchi; Mitsuru Futakuchi; Dae Joong Kim; L Cui; Nobuyuki Ito
Phenotypic alteration of hepatocellular foci in rats treated with clofibrate and phenobarbital.
Cancer letters 1994;83(1-2):89-95.
1994: Masao Hirose; Toru Hoshiya; Keisuke Akagi; Mitsuru Futakuchi; Nobuyuki Ito
Inhibition of mammary gland carcinogenesis by green tea catechins and other naturally occurring antioxidants in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz[alpha]anthracene.
Cancer letters 1994;83(1-2):149-56.
1994: Tomoyuki Shirai; Masashi Sano; Katsumi Imaida; Satoru Takahashi; T Mori; Nobuyuki Ito
Duration dependent induction of invasive prostatic carcinomas with pharmacological dose of testosterone propionate in rats pretreated with 3,2'-dimethyl-4-aminobiphenyl and development of androgen-independent carcinomas after castration.
Cancer letters 1994;83(1-2):111-6.
1994: Harunari Tanaka; A Hagiwara; Y Kurata; T Ogiso; Mitsuru Futakuchi; Nobuyuki Ito
Thirteen-week oral toxicity study of magnesium chloride in B6C3F1 mice.
Toxicology letters 1994;73(1):25-32.
1994: R Hasegawa; E Miyata; Mitsuru Futakuchi; A Hagiwara; M Nagao; T Sugimura; Nobuyuki Ito
Synergistic enhancement of hepatic foci development by combined treatment of rats with 10 heterocyclic amines at low doses.
Carcinogenesis 1994;15(5):1037-41.
1994: Tomoyuki Shirai; Katsumi Imaida; T Masui; S Iwasaki; T Mori; T Kato; Nobuyuki Ito
Effects of testosterone, dihydrotestosterone and estrogen on 3,2'-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis.
International journal of cancer. Journal international du cancer 1994;57(2):224-8.
1994: P Puapairoj; L Cui; Kumiko Ogawa; Keisuke Akagi; R Hasegawa; Nobuyuki Ito
Effect of ethanol on paraquat toxicity in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(4):379-86.
1994: W Thamavit; Chawalit Pairojkul; Danai Tiwawech; Tomoyuki Shirai; Nobuyuki Ito
Strong promoting effect of Opisthorchis viverrini infection on dimethylnitrosamine-initiated hamster liver.
Cancer letters 1994;78(1-3):121-5.
1994: L Cui; R Hasegawa; F Zajdela; P Puapairoj; Tomoyuki Shirai; Nobuyuki Ito
Lack of promoting activity of 7-methoxy-2-nitro-naphtho-[2,1-b]furan (R7000) in a medium-term rat liver bioassay.
Cancer letters 1994;76(2-3):161-6.
1994: E Asakawa; Masao Hirose; A Hagiwara; Satoru Takahashi; Nobuyuki Ito
Carcinogenicity of 4-methoxyphenol and 4-methylcatechol in F344 rats.
International journal of cancer. Journal international du cancer 1994;56(1):146-52.
1994: Y Yoshida; Masao Hirose; K Takaba; J Kimura; Nobuyuki Ito
Induction and promotion of forestomach tumors by sodium nitrite in combination with ascorbic acid or sodium ascorbate in rats with or without N-methyl-N'-nitro-N-nitrosoguanidine pre-treatment.
International journal of cancer. Journal international du cancer 1994;56(1):124-8.
1994: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; Satoru Takahashi; Tomoyuki Shirai
Medium-term rat liver bioassay for rapid detection of carcinogens and modifiers of hepatocarcinogenesis.
Drug metabolism reviews 1994;26(1-2):431-42.
1994: W Thamavit; Chawalit Pairojkul; Danai Tiwawech; Tomoyuki Shirai; Nobuyuki Ito
Lack of promoting effect of proline on bile duct cancer development in dimethylnitrosamine-initiated hamster livers.
Teratogenesis, carcinogenesis, and mutagenesis 1994;14(4):169-74.
1993: R Hasegawa; Masashi Sano; Seiko Tamano; Katsumi Imaida; Tomoyuki Shirai; M Nagao; T Sugimura; Nobuyuki Ito
Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats.
Carcinogenesis 1993;14(12):2553-7.
1993: Nobuyuki Ito; Masao Hirose; Satoru Takahashi
Cell proliferation and forestomach carcinogenesis.
Environmental health perspectives 1993;101 Suppl 5():107-10.
1993: S Takahashi; T Shirai; K Ogawa; K Imaida; Chikao Yamazaki; A Ito; K Masuko; Nobuyuki Ito
Renal cell adenomas and carcinomas in hemodialysis patients: relationship between hemodialysis period and development of lesions.
Acta pathologica japonica 1993;43(11):674-82.
1993: W Thamavit; Chawalit Pairojkul; Danai Tiwawech; Makoto Itoh; Tomoyuki Shirai; Nobuyuki Ito
Promotion of cholangiocarcinogenesis in the hamster liver by bile duct ligation after dimethylnitrosamine initiation.
Carcinogenesis 1993;14(11):2415-7.
1993: Masao Hirose; H Yada; K Hakoi; Satoru Takahashi; Nobuyuki Ito
Modification of carcinogenesis by alpha-tocopherol, t-butylhydroquinone, propyl gallate and butylated hydroxytoluene in a rat multi-organ carcinogenesis model.
Carcinogenesis 1993;14(11):2359-64.
1993: Tomoyuki Shirai; S Iwasaki; T Masui; T Mori; T Kato; Nobuyuki Ito
Enhancing effect of cadmium on rat ventral prostate carcinogenesis induced by 3,2'-dimethyl-4-aminobiphenyl.
Japanese journal of cancer research : Gann 1993;84(10):1023-30.
1993: Y Yoshida; M Tatematsu; K Takaba; S Iwasaki; Nobuyuki Ito
Target organ specificity of cell proliferation induced by various carcinogens.
Toxicologic pathology 1993;21(5):436-42.
1993: Toru Hoshiya; R Hasegawa; K Hakoi; L Cui; Tadashi Ogiso; R Cabral; Nobuyuki Ito
Enhancement by non-mutagenic pesticides of GST-P positive hepatic foci development initiated with diethylnitrosamine in the rat.
Cancer letters 1993;72(1-2):59-64.
1993: Masao Hirose; Toru Hoshiya; Keisuke Akagi; Satoru Takahashi; Y Hara; Nobuyuki Ito
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Carcinogenesis 1993;14(8):1549-53.
1993: Mayumi Kawabe; Seiko Tamano; M A Shibata; Masao Hirose; S Fukushima; Nobuyuki Ito
Subchronic toxicity study of methyl hesperidin in mice.
Toxicology letters 1993;69(1):37-44.
1993: M A Shibata; Masao Hirose; A Masuda; T Kato; M Mutai; Nobuyuki Ito
Modification of BHA forestomach carcinogenesis in rats: inhibition by diethylmaleate or indomethacin and enhancement by a retinoid.
Carcinogenesis 1993;14(7):1265-9.
1993: R Hasegawa; R Cabral; Toru Hoshiya; K Hakoi; Tadashi Ogiso; P Boonyaphiphat; Tomoyuki Shirai; Nobuyuki Ito
Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats.
International journal of cancer. Journal international du cancer 1993;54(3):489-93.
1993: Masao Hirose; Keisuke Akagi; R Hasegawa; T Satoh; Y Nihro; Tokutaro Miki; T Sugimura; Nobuyuki Ito
Strong inhibition of 2-amino-6-methyldipyrido[1,2-a:3',2'-d] imidazole-induced mutagenesis and hepatocarcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone.
Japanese journal of cancer research : Gann 1993;84(5):481-4.
1993: A Hagiwara; Harunari Tanaka; Katsumi Imaida; Seiko Tamano; S Fukushima; Nobuyuki Ito
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats.
Japanese journal of cancer research : Gann 1993;84(3):237-45.
1993: Masao Hirose; S Fukushima; Harunari Tanaka; E Asakawa; Satoru Takahashi; Nobuyuki Ito
Carcinogenicity of catechol in F344 rats and B6C3F1 mice.
Carcinogenesis 1993;14(3):525-9.
1993: W Thamavit; Malcolm Moore; Stitaya Sirisinha; Tomoyuki Shirai; Nobuyuki Ito
Time-dependent modulation of liver lesion development in Opisthorchis-infected Syrian hamster by an antihelminthic drug, praziquantel.
Japanese journal of cancer research : Gann 1993;84(2):135-8.
1993: M A Shibata; Masao Hirose; M Kagawa; P Boonyaphiphat; Nobuyuki Ito
Enhancing effect of concomitant L-ascorbic acid administration on BHA-induced forestomach carcinogenesis in rats.
Carcinogenesis 1993;14(2):275-80.
1993: Tomoyuki Shirai; Katsumi Imaida; S Iwasaki; T Mori; M Tada; Nobuyuki Ito
Sequential observation of rat prostate lesion development induced by 3,2'-dimethyl-4-aminobiphenyl and testosterone.
Japanese journal of cancer research : Gann 1993;84(1):20-5.
1993: Seiko Tamano; Mayumi Kawabe; Masashi Sano; T Masui; Nobuyuki Ito
Subchronic oral toxicity study of captafol in B6C3F1 mice.
Journal of toxicology and environmental health 1993;38(1):69-75.
1993: Masao Hirose; Harunari Tanaka; Satoru Takahashi; Mitsuru Futakuchi; S Fukushima; Nobuyuki Ito
Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model.
Cancer research 1993;53(1):32-7.
1993: Masao Hirose; Tomoyuki Shirai; Satoru Takahashi; Kumiko Ogawa; Nobuyuki Ito
Organ-specific modification of carcinogenesis by antioxidants in rats.
Basic life sciences 1993;61():181-8.
1993: J L de Camargo; Hiroyuki Tsuda; Makoto Asamoto; Y Tagawa; S Wada; S Nagase; Nobuyuki Ito
Modifying effects of chemicals on the development of liver preneoplastic placental glutathione S-transferase positive foci in analbuminemic and Sprague-Dawley rats.
Toxicologic pathology 1993;21(4):409-16.
1993: A Hagiwara; Danai Tiwawech; Katsumi Imaida; Seiko Tamano; M A Shibata; S Fukushima; Nobuyuki Ito
Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay.
Teratogenesis, carcinogenesis, and mutagenesis 1993;13(6):277-87.
1992: R Hasegawa; Kumiko Ogawa; K Takaba; Tomoyuki Shirai; Nobuyuki Ito
3,2'-Dimethyl-4-aminobiphenyl-induced gallbladder carcinogenesis and effects of ethinyl estradiol in hamsters.
Japanese journal of cancer research : Gann 1992;83(12):1286-92.
1992: Seiko Tamano; Masao Hirose; Harunari Tanaka; E Asakawa; Kumiko Ogawa; Nobuyuki Ito
Forestomach neoplasm induction in F344/DuCrj rats and B6C3F1 mice exposed to sesamol.
Japanese journal of cancer research : Gann 1992;83(12):1279-85.
1992: Nobuyuki Ito; R Hasegawa; Katsumi Imaida; T Masui; Satoru Takahashi; Tomoyuki Shirai
Pathological markers for non-genotoxic agent-associated carcinogenesis.
Toxicology letters 1992;64-65 Spec No():613-20.
1992: R Hasegawa; Nobuyuki Ito
Liver medium-term bioassay in rats for screening of carcinogens and modifying factors in hepatocarcinogenesis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(11):979-92.
1992: Hiroyuki Tsuda; K Ozaki; S Uwagawa; S Yamaguchi; K Hakoi; T Aoki; T Kato; K Sato; Nobuyuki Ito
Effects of modifying agents on conformity of enzyme phenotype and proliferative potential in focal preneoplastic and neoplastic liver cell lesions in rats.
Japanese journal of cancer research : Gann 1992;83(11):1154-65.
1992: Y Shichino; M Tatematsu; H Ohshima; H Bartsch; C Furihata; Nobuyuki Ito
Effects of hickory-smoke condensate on development of pepsinogen 1-altered pyloric glands in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(10):859-64.
1992: Masao Hirose; Mayumi Kawabe; M Shibata; Satoru Takahashi; S Okazaki; Nobuyuki Ito
Influence of caffeic acid and other o-dihydroxybenzene derivatives on N-methyl-N'-nitro-N-nitrosoguanidine-initiated rat forestomach carcinogenesis.
Carcinogenesis 1992;13(10):1825-8.
1992: A Hagiwara; Masashi Sano; E Asakawa; Harunari Tanaka; R Hasegawa; Nobuyuki Ito
Enhancing effects of harman and norharman on induction of preneoplastic and neoplastic kidney lesions in rats initiated with N-ethyl-N-hydroxyethylnitrosamine.
Japanese journal of cancer research : Gann 1992;83(9):949-54.
1992: M Tatematsu; Kumiko Ogawa; Toru Hoshiya; Y Shichino; T Kato; Katsumi Imaida; Nobuyuki Ito
Induction of adenocarcinomas in the glandular stomach of BALB/c mice treated with N-methyl-N-nitrosourea.
Japanese journal of cancer research : Gann 1992;83(9):915-8.
1992: Satoru Takahashi; K Hakoi; H Yada; Masao Hirose; Nobuyuki Ito; S Fukushima
Enhancing effects of diallyl sulfide on hepatocarcinogenesis and inhibitory actions of the related diallyl disulfide on colon and renal carcinogenesis in rats.
Carcinogenesis 1992;13(9):1513-8.
1992: R Hasegawa; Satoru Takahashi; Tomoyuki Shirai; S Iwasaki; Dae Joong Kim; M Ochiai; M Nagao; T Sugimura; Nobuyuki Ito
Dose-dependent formation of preneoplastic foci and DNA adducts in rat liver with 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alpha C) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Carcinogenesis 1992;13(8):1427-31.
1992: S Uwagawa; Hiroyuki Tsuda; K Ozaki; Satoru Takahashi; S Yamaguchi; M Mutai; T Aoki; Nobuyuki Ito
Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model.
Japanese journal of cancer research : Gann 1992;83(8):812-20.
1992: A Hagiwara; P Boonyaphiphat; Mayumi Kawabe; H Naito; Tomoyuki Shirai; Nobuyuki Ito
Lack of carcinogenicity of tragacanth gum in B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(8):673-9.
1992: R Hasegawa; Danai Tiwawech; Masao Hirose; K Takaba; Toru Hoshiya; Tomoyuki Shirai; Nobuyuki Ito
Suppression of diethylnitrosamine-initiated preneoplastic foci development in the rat liver by combined administration of four antioxidants at low doses.
Japanese journal of cancer research : Gann 1992;83(5):431-7.
1992: Masao Hirose; S Wada; S Yamaguchi; A Masuda; S Okazaki; Nobuyuki Ito
Reversibility of catechol-induced rat glandular stomach lesions.
Cancer research 1992;52(4):787-90.
1992: W Thamavit; Malcolm Moore; S Ruchirawat; Nobuyuki Ito
Repeated exposure to Opisthorchis viverrini and treatment with the antihelminthic Praziquantel lacks carcinogenic potential.
Carcinogenesis 1992;13(2):309-11.
1992: W Thamavit; Malcolm Moore; S Ruchirawat; Nobuyuki Ito
Lack of modulation effects of praziquantel on DMN-induced lesion development in the Syrian hamster liver.
Cancer letters 1992;61(3):229-32.
1992: M A Shibata; S Fukushima; E Asakawa; Masao Hirose; Nobuyuki Ito
The modifying effects of indomethacin or ascorbic acid on cell proliferation induced by different types of bladder tumor promoters in rat urinary bladder and forestomach mucosal epithelium.
Japanese journal of cancer research : Gann 1992;83(1):31-9.
1992: T Shirari; Seiko Tamano; Satoru Takahashi; Nobuyuki Ito
Animal prostate carcinoma models: limited potential for vertebral metastasis.
Advances in experimental medicine and biology 1992;324():151-8.
1992: A Hagiwara; E Asakawa; Y Kurata; Masashi Sano; Masao Hirose; Nobuyuki Ito
Dose-dependent renal tubular toxicity of harman and norharman in male F344 rats.
Toxicologic pathology 1992;20(2):197-204.
1992: Nobuyuki Ito; Tomoyuki Shirai; R Hasegawa
Medium-term bioassays for carcinogens.
IARC scientific publications 1992;(116):353-88.
1992: M Tatematsu; R Hasegawa; Kumiko Ogawa; T Kato; M Ichinose; K Miki; Nobuyuki Ito
Histogenesis of human stomach cancers based on assessment of differentiation.
Journal of clinical gastroenterology 1992;14 Suppl 1():S1-7.
1992: K Hakoi; R Cabral; Toru Hoshiya; R Hasegawa; Tomoyuki Shirai; Nobuyuki Ito
Analysis of carcinogenic activity of some pesticides in a medium-term liver bioassay in the rat.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(6):269-76.
1992: R Hasegawa; C Y Wang; Dae Joong Kim; M S Lee; Y Yoshida; Nobuyuki Ito
Effect of acyl derivatives of 4,4,4-trifluoro-1-phenyl-1,3-butanedione on 2-acetylaminofluorene-induced glutathione S-transferase positive foci in the rat liver.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(6):263-8.
1992: Y Yoshida; M Tatematsu; K Takaba; Y Shichino; Nobuyuki Ito
Effects of various bile acids and their sodium salts on development of pepsinogen-altered pyloric glands in rats.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(4):179-86.
1992: Nobuyuki Ito; Katsumi Imaida
Strategy of research for cancer--chemoprevention.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(2):79-95.
1992: Y Yoshida; R Hasegawa; K Takaba; Katsumi Imaida; Nobuyuki Ito
N-nitrosoheptamethyleneimine-induced pulmonary and esophageal carcinogenesis and effects of concomitant treatment with bleomycin in rats.
Teratogenesis, carcinogenesis, and mutagenesis 1992;12(5):197-201.
1991: S Uwagawa; Hiroyuki Tsuda; T Inoue; Y Tagawa; T Aoki; M Kagawa; Tadashi Ogiso; Nobuyuki Ito
Enhancing potential of 6 different carcinogens on multi-organ tumorigenesis after initial treatment with N-methyl-N-nitrosourea in rats.
Japanese journal of cancer research : Gann 1991;82(12):1397-405.
1991: R Hasegawa; Tomoyuki Shirai; K Hakoi; K Takaba; S Iwasaki; Toru Hoshiya; Nobuyuki Ito; M Nagao; T Sugimura
Synergistic enhancement of glutathione S-transferase placental form-positive hepatic foci development in diethylnitrosamine-treated rats by combined administration of five heterocyclic amines at low doses.
Japanese journal of cancer research : Gann 1991;82(12):1378-84.
1991: M A Shibata; Masao Hirose; Harunari Tanaka; E Asakawa; Tomoyuki Shirai; Nobuyuki Ito
Induction of renal cell tumors in rats and mice, and enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment.
Japanese journal of cancer research : Gann 1991;82(11):1211-9.
1991: A Hagiwara; Masao Hirose; Satoru Takahashi; Kumiko Ogawa; Tomoyuki Shirai; Nobuyuki Ito
Forestomach and kidney carcinogenicity of caffeic acid in F344 rats and C57BL/6N x C3H/HeN F1 mice.
Cancer research 1991;51(20):5655-60.
1991: Masao Hirose; S Uwagawa; K Ozaki; K Takaba; Nobuyuki Ito
Effects of butylated hydroxyanisole pretreatment on low dose N-methyl-N'-nitro-N-nitrosoguanidine- or N,N-dibutylnitrosamine-induced rat forestomach or esophageal carcinogenesis.
Carcinogenesis 1991;12(10):1773-6.
1991: Tomoyuki Shirai; K D Joong; K Hakoi; W Thamavit; Chawalit Pairojkul; Toru Hoshiya; R Hasegawa; Nobuyuki Ito
Promotion of rat hepatocarcinogenesis by praziquantel.
Japanese journal of cancer research : Gann 1991;82(10):1085-8.
1991: A Hagiwara; Harunari Tanaka; Danai Tiwawech; Tomoyuki Shirai; Nobuyuki Ito
Oral toxicity study of tragacanth gum in B6C3F1 mice: development of squamous-cell hyperplasia in the forestomach and its reversibility.
Journal of toxicology and environmental health 1991;34(2):207-18.
1991: Masao Hirose; K Ozaki; K Takaba; S Fukushima; Tomoyuki Shirai; Nobuyuki Ito
Modifying effects of the naturally occurring antioxidants gamma-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model.
Carcinogenesis 1991;12(10):1917-21.
1991: Nobuyuki Ito; R Hasegawa; Masashi Sano; Seiko Tamano; H Esumi; S Takayama; T Sugimura
A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Carcinogenesis 1991;12(8):1503-6.
1991: Seiko Tamano; Y Kurata; M Shibata; Harunari Tanaka; Tadashi Ogiso; Nobuyuki Ito
13-Week oral toxicity study of captafol in F344/DuCrj rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1991;17(2):390-8.
1991: A Nakamura; Tomoyuki Shirai; Satoru Takahashi; Kumiko Ogawa; Masao Hirose; Nobuyuki Ito
Lack of modification by naturally occurring antioxidants of 3,2'-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis.
Cancer letters 1991;58(3):241-6.
1991: S Fukushima; M A Shibata; Masao Hirose; T Kato; M Tatematsu; Nobuyuki Ito
Organ-specific modification of tumor development by low-dose combinations of agents in a rat wide-spectrum carcinogenesis model.
Japanese journal of cancer research : Gann 1991;82(7):784-92.
1991: Tomoyuki Shirai; S Fukushima; Mayumi Kawabe; M Shibata; S Iwasaki; M Tada; Nobuyuki Ito
Selective induction of rat urinary bladder tumors by simultaneous administration of 3,2'-dimethyl-4-aminobiphenyl (DMAB) and butylated hydroxyanisole or butylated hydroxytoluene is associated with increased DMAB-DNA adduct formation.
Carcinogenesis 1991;12(7):1335-9.
1991: R Cabral; Toru Hoshiya; K Hakoi; R Hasegawa; S Fukushima; Nobuyuki Ito
A rapid in vivo bioassay for the carcinogenicity of pesticides.
Tumori 1991;77(3):185-8.
1991: Danai Tiwawech; R Hasegawa; Y Kurata; M Tatematsu; M A Shibata; W Thamavit; Nobuyuki Ito
Dose-dependent effects of 2-acetylaminofluorene on hepatic foci development and cell proliferation in rats.
Carcinogenesis 1991;12(6):985-90.
1991: S Fukushima; A Hagiwara; Masao Hirose; S Yamaguchi; Danai Tiwawech; Nobuyuki Ito
Modifying effects of various chemicals on preneoplastic and neoplastic lesion development in a wide-spectrum organ carcinogenesis model using F344 rats.
Japanese journal of cancer research : Gann 1991;82(6):642-9.
1991: Nobuyuki Ito; R Hasegawa; Tomoyuki Shirai; S Fukushima; K Hakoi; K Takaba; S Iwasaki; K Wakabayashi; M Nagao; T Sugimura
Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
Carcinogenesis 1991;12(5):767-72.
1991: R Hasegawa; Satoru Takahashi; Katsumi Imaida; S Yamaguchi; Tomoyuki Shirai; Nobuyuki Ito
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine.
Japanese journal of cancer research : Gann 1991;82(3):293-7.
1991: Tomoyuki Shirai; Seiko Tamano; T Kato; S Iwasaki; Satoru Takahashi; Nobuyuki Ito
Induction of invasive carcinomas in the accessory sex organs other than the ventral prostate of rats given 3,2'-dimethyl-4-aminobiphenyl and testosterone propionate.
Cancer research 1991;51(4):1264-9.
1991: Masao Hirose; M Mutai; Satoru Takahashi; M Yamada; S Fukushima; Nobuyuki Ito
Effects of phenolic antioxidants in low dose combination on forestomach carcinogenesis in rats pretreated with N-methyl-N'-nitro-N-nitrosoguanidine.
Cancer research 1991;51(3):824-7.
1991: Nobuyuki Ito; Tomoyuki Shirai; S Fukushima
Medium-term bioassay for carcinogens using multiorgan models.
Progress in experimental tumor research 1991;33():41-57.
1991: Nobuyuki Ito; Tomoyuki Shirai; T Masui; Kumiko Ogawa; T Kato; Satoru Takahashi
Mechanistic analysis of multistage carcinogenesis in the rat prostate.
Princess Takamatsu symposia 1991;22():125-33.
1991: M Tatematsu; Kumiko Ogawa; M Mutai; T Aoki; Toru Hoshiya; Nobuyuki Ito
Rapid regression of squamous cell hyperplasia and slow regression of basal cell hyperplasia in the forestomach of F344 rats treated with N-methyl-N'-nitro-N-nitrosoguanidine and/or butylated hydroxyanisole.
Cancer research 1991;51(1):318-23.
1991: Kumiko Ogawa; R Hasegawa; S Wada; S Yamaguchi; Nobuyuki Ito
Dose response study of N-nitrosodiethanolamine initiation of rat hepatocarcinogenesis.
Teratogenesis, carcinogenesis, and mutagenesis 1991;11(5):245-50.
1990: S Yamaguchi; M Tatematsu; C Furihata; K Takaba; Nobuyuki Ito
Effects of bile acids on development of pepsinogen-altered pyloric glands in rats.
Cancer letters 1990;55(2):129-34.
1990: Seiko Tamano; Y Kurata; Mayumi Kawabe; A Yamamoto; A Hagiwara; R Cabral; Nobuyuki Ito
Carcinogenicity of captafol in F344/DuCrj rats.
Japanese journal of cancer research : Gann 1990;81(12):1222-31.
1990: Katsumi Imaida; Masao Hirose; S Yamaguchi; Satoru Takahashi; Nobuyuki Ito
Effects of naturally occurring antioxidants on combined 1,2-dimethylhydrazine- and 1-methyl-1-nitrosourea-initiated carcinogenesis in F344 male rats.
Cancer letters 1990;55(1):53-9.
1990: Makoto Asamoto; Y Shichino; Hiroyuki Tsuda; Nobuyuki Ito
Inhibition of rat hepatic glutathione S-transferase placental form positive foci development by concomitant administration of antioxidants to carcinogen-treated rats.
Cancer letters 1990;55(1):25-9.
1990: M Tatematsu; K Ozaki; M Mutai; Y Shichino; C Furihata; Nobuyuki Ito
Enhancing effects of various gastric carcinogens on development of pepsinogen-altered pyloric glands in rats.
Carcinogenesis 1990;11(11):1975-8.
1990: A Hagiwara; M Yamada; R Hasegawa; S Fukushima; Nobuyuki Ito
Lack of enhancing effects of fenvalerate and esfenvalerate on induction of preneoplastic glutathione S-transferase placental form positive liver cell foci in rats.
Cancer letters 1990;54(1-2):67-73.
1990: S Wada; Masao Hirose; Satoru Takahashi; S Okazaki; Nobuyuki Ito
Para-methoxyphenol strongly stimulates cell proliferation in the rat forestomach but is not a promoter of rat forestomach carcinogenesis.
Carcinogenesis 1990;11(10):1891-4.
1990: Y Kurata; S Fukushima; A Hagiwara; H Ito; Kumiko Ogawa; Nobuyuki Ito
Carcinogenicity study of methyl hesperidin in B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1990;28(9):613-8.
1990: A Nakamura; Tomoyuki Shirai; Kumiko Ogawa; S Wada; N A Fujimoto; A Ito; Nobuyuki Ito
Promoting action of prolactin released from a grafted transplantable pituitary tumor (MtT/F84) on rat prostate carcinogenesis.
Cancer letters 1990;53(2-3):151-7.
1990: Masao Hirose; S Fukushima; R Hasegawa; T Kato; Harunari Tanaka; Nobuyuki Ito
Effects of sodium nitrite and catechol or 3-methoxycatechol in combination on rat stomach epithelium.
Japanese journal of cancer research : Gann 1990;81(9):857-61.
1990: Y Kurata; S Fukushima; R Hasegawa; Masao Hirose; M Shibata; Tomoyuki Shirai; Nobuyuki Ito
Structure-activity relations in promotion of rat urinary bladder carcinogenesis by phenolic antioxidants.
Japanese journal of cancer research : Gann 1990;81(8):754-9.
1990: M Tatematsu; T Katsuyama; C Furihata; S Fukushima; Tomoyuki Shirai; T Kato; Nobuyuki Ito
Cellular differentiation and histogenesis of rat glandular stomach cancers.
Japanese journal of cancer research : Gann 1990;81(8):760-7.
1990: M Tatematsu; M Ichinose; K Miki; R Hasegawa; T Kato; Nobuyuki Ito
Gastric and intestinal phenotypic expression of human stomach cancers as revealed by pepsinogen immunohistochemistry and mucin histochemistry.
Acta pathologica japonica 1990;40(7):494-504.
1990: M A Shibata; Masao Hirose; M Yamada; M Tatematsu; S Uwagawa; Nobuyuki Ito
Epithelial cell proliferation in rat forestomach and glandular stomach mucosa induced by catechol and analogous dihydroxybenzenes.
Carcinogenesis 1990;11(6):997-1000.
1990: M A Shibata; S Fukushima; Satoru Takahashi; R Hasegawa; Nobuyuki Ito
Enhancing effects of sodium phenobarbital and N,N-dibutylnitrosamine on tumor development in a rat wide-spectrum organ carcinogenesis model.
Carcinogenesis 1990;11(6):1027-31.
1990: Tomoyuki Shirai; A Nakamura; S Fukushima; A Yamamoto; M Tada; Nobuyuki Ito
Different carcinogenic responses in a variety of organs, including the prostate, of five different rat strains given 3,2'-dimethyl-4-aminobiphenyl.
Carcinogenesis 1990;11(5):793-7.
1990: Masao Hirose; A Masuda; Nobuyuki Ito; K Kamano; Harumi Okuyama
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
Carcinogenesis 1990;11(5):731-5.
1990: Tomoyuki Shirai; A Nakamura; S Fukushima; M Tada; T Morita; Nobuyuki Ito
Immunohistochemical demonstration of carcinogen-DNA adducts in target and non-target tissues of rats given a prostate carcinogen, 3,2'-dimethyl-4-aminobiphenyl.
Carcinogenesis 1990;11(4):653-7.
1990: Tadashi Ogiso; M Tatematsu; Seiko Tamano; R Hasegawa; Nobuyuki Ito
Correlation between medium-term liver bioassay system data and results of long-term testing in rats.
Carcinogenesis 1990;11(4):561-6.
1990: Hiroyuki Tsuda; Satoru Takahashi; S Yamaguchi; K Ozaki; Nobuyuki Ito
Comparison of initiation potential of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in an in vivo carcinogen bioassay system.
Carcinogenesis 1990;11(4):549-52.
1990: Tomoyuki Shirai; A Nakamura; S Fukushima; C Y Wang; H Yamada; Nobuyuki Ito
Selective induction of prostate carcinomas in F344 rats treated with intraperitoneal injections of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl.
Japanese journal of cancer research : Gann 1990;81(4):320-3.
1990: M A Shibata; M Yamada; Masao Hirose; E Asakawa; M Tatematsu; Nobuyuki Ito
Early proliferative responses of forestomach and glandular stomach of rats treated with five different phenolic antioxidants.
Carcinogenesis 1990;11(3):425-9.
1990: Masao Hirose; S Fukushima; Tomoyuki Shirai; R Hasegawa; T Kato; Harunari Tanaka; E Asakawa; Nobuyuki Ito
Stomach carcinogenicity of caffeic acid, sesamol and catechol in rats and mice.
Japanese journal of cancer research : Gann 1990;81(3):207-12.
1990: Hiroyuki Tsuda; S Wada; T Masui; M Inui; Nobuyuki Ito; K Katagiri; M Hoshino; H Inaguma; M Miyaji; T Takeuchi
Comparative sequential changes in serum and biliary levels of bile acid components after a single dose of D-galactosamine or partial hepatectomy in the rat.
Liver 1990;10(1):28-34.
1990: M Mutai; M Tatematsu; T Aoki; S Wada; Nobuyuki Ito
Modulatory interaction between initial clofibrate treatment and subsequent administration of 2-acetylaminofluorene or sodium phenobarbital on glutathione S-transferase positive lesion development.
Cancer letters 1990;49(2):127-32.
1990: Masao Hirose; A Masuda; R Hasegawa; S Wada; Nobuyuki Ito
Regression of butylated hydroxyanisole (BHA)-induced hyperplasia but not dysplasia in the forestomach of hamsters.
Carcinogenesis 1990;11(2):239-44.
1990: Nobuyuki Ito; Masao Hirose; A Hagiwara; Satoru Takahashi
Carcinogenicity and modification of carcinogenic response by antioxidants.
Basic life sciences 1990;52():183-94.
1990: A Hagiwara; Harunari Tanaka; Y Kurata; T Kato; Hiroyuki Tsuda; Nobuyuki Ito
Lack of hepatotoxicity or promotion of enzyme-altered liver foci development in rats treated with harman or norharman.
Journal of toxicology and environmental health 1990;29(2):211-8.
1989: Nobuyuki Ito; Masao Hirose; M Shibata; Harunari Tanaka; Tomoyuki Shirai
Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2'-dimethyl-4-aminobiphenyl, 2,2'-dihydroxy-di-n-propylnitrosamine and N-methylnitrosourea.
Carcinogenesis 1989;10(12):2255-9.
1989: Masao Hirose; M Kagawa; Kumiko Ogawa; A Yamamoto; Nobuyuki Ito
Antagonistic effect of diethylmaleate on the promotion of forestomach carcinogenesis by butylated hydroxyanisole (BHA) in rats pretreated with N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis 1989;10(12):2223-6.
1989: S Yamaguchi; Masao Hirose; S Fukushima; R Hasegawa; Nobuyuki Ito
Modification by catechol and resorcinol of upper digestive tract carcinogenesis in rats treated with methyl-N-amylnitrosamine.
Cancer research 1989;49(21):6015-8.
1989: Makoto Asamoto; Hiroyuki Tsuda; T Kato; Nobuyuki Ito; T Masuko; Y Hashimoto; S Nagase
Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of hepatocarcinogenesis: immunohistochemical analysis of cytochrome P-450 isozyme induction by 2-acetylaminofluorene and phenobarbital.
Japanese journal of cancer research : Gann 1989;80(11):1041-6.
1989: M Tatematsu; M Mutai; K Inoue; K Ozaki; C Furihata; Nobuyuki Ito
Synergism between sodium chloride and sodium taurocholate and development of pepsinogen-altered pyloric glands: relevance to a medium-term bioassay system for gastric carcinogens and promoters in rats.
Japanese journal of cancer research : Gann 1989;80(11):1035-40.
1989: Makoto Asamoto; Hiroyuki Tsuda; M Kagawa; J L de Camargo; Nobuyuki Ito; S Nagase
Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system: quantitation of glutathione S-transferase P-positive foci development.
Japanese journal of cancer research : Gann 1989;80(10):939-44.
1989: R Hasegawa; M Mutai; Katsumi Imaida; Hiroyuki Tsuda; S Yamaguchi; Nobuyuki Ito
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver.
Japanese journal of cancer research : Gann 1989;80(10):945-51.
1989: Masao Hirose; S Yamaguchi; S Fukushima; R Hasegawa; Satoru Takahashi; Nobuyuki Ito
Promotion by dihydroxybenzene derivatives of N-methyl-N'-nitro-N-nitrosoguanidine-induced F344 rat forestomach and glandular stomach carcinogenesis.
Cancer research 1989;49(18):5143-7.
1989: Masao Hirose; Y Kurata; M Yamada; Tomoyuki Shirai; Nobuyuki Ito; T Ohsawa
Lack of modifying effects of linolic acid hydroperoxides and their secondary oxidative products on combined 7,12-dimethylbenz[a]anthracene and 1,2-dimethylhydrazine-initiated mammary gland, ear duct and colon carcinogenesis in female Sprague-Dawley rats.
Cancer letters 1989;47(1-2):141-7.
1989: Y Kurata; Seiko Tamano; M A Shibata; A Hagiwara; S Fukushima; Nobuyuki Ito
Lack of carcinogenicity of magnesium chloride in a long-term feeding study in B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1989;27(9):559-63.
1989: S Fukushima; T Inoue; S Uwagawa; M A Shibata; Nobuyuki Ito
Co-carcinogenic effects of NaHCO3 on o-phenylphenol-induced rat bladder carcinogenesis.
Carcinogenesis 1989;10(9):1635-40.
1989: Tomoyuki Shirai; A Nakamura; S Wada; Nobuyuki Ito
Pancreatic acinar cell tumors in rats induced by 3,2'-dimethyl-4-aminobiphenyl.
Carcinogenesis 1989;10(6):1127-30.
1989: M Tatematsu; T Katsuyama; M Mutai; E Asakawa; Nobuyuki Ito
Pyloric gland phenotypic expression of gastric cancers developing in the rat fundic glandular stomach.
Carcinogenesis 1989;10(6):1033-9.
1989: M Tatematsu; M Mutai; T Aoki; J L de Camargo; C Furihata; Nobuyuki Ito
Proliferation kinetics of pepsinogen altered pyloric gland cells in rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis 1989;10(5):907-11.
1989: W Thamavit; S Fukushima; Y Kurata; Makoto Asamoto; Nobuyuki Ito
Modification by sodium L-ascorbate, butylated hydroxytoluene, phenobarbital and pepleomycin of lesion development in a wide-spectrum initiation rat model.
Cancer letters 1989;45(2):93-101.
1989: Katsumi Imaida; M Tatematsu; T Kato; Hiroyuki Tsuda; Nobuyuki Ito
Advantages and limitations of stereological estimation of placental glutathione S-transferase-positive rat liver cell foci by computerized three-dimensional reconstruction.
Japanese journal of cancer research : Gann 1989;80(4):326-30.
1989: Nobuyuki Ito; A Hagiwara; Seiko Tamano; M Kagawa; M Shibata; Y Kurata; S Fukushima
Lack of carcinogenicity of quercetin in F344/DuCrj rats.
Japanese journal of cancer research : Gann 1989;80(4):317-25.
1989: Tomoyuki Shirai; A Nakamura; S Fukushima; Satoru Takahashi; Kumiko Ogawa; Nobuyuki Ito
Effects of age on multiple organ carcinogenesis induced by 3,2'-dimethyl-4-aminobiphenyl in rats, with particular reference to the prostate.
Japanese journal of cancer research : Gann 1989;80(4):312-6.
1989: S Fukushima; Makoto Asamoto; K Imaida; M N el-Bolkainy; H N Tawfik; Nobuyuki Ito
Comparative study of urinary bladder carcinomas in Japanese and Egyptians.
Acta pathologica japonica 1989;39(3):176-9.
1989: Tomoyuki Shirai; S Fukushima; Y Tagawa; M Okumura; Nobuyuki Ito
Cell proliferation induced by uracil-calculi and subsequent development of reversible papillomatosis in the rat urinary bladder.
Cancer research 1989;49(2):378-83.
1989: R Hasegawa; S Fukushima; A Hagiwara; T Masui; A Masuda; Nobuyuki Ito
Long-term feeding study of N,N'-diphenyl-p-phenylenediamine in F344 rats.
Toxicology 1989;54(1):69-78.
1989: Nobuyuki Ito; S Fukushima; R Hasegawa
Bladder cancers. Their process of development and its modification.
Acta pathologica japonica 1989;39(1):1-14.
1989: Nobuyuki Ito; Masao Hirose
Antioxidants--carcinogenic and chemopreventive properties.
Advances in cancer research 1989;53():247-302.
1989: Nobuyuki Ito; Katsumi Imaida; R Hasegawa; Hiroyuki Tsuda
Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis.
Critical reviews in toxicology 1989;19(4):385-415.
1989: Nobuyuki Ito; M Tatematsu; R Hasegawa; Hiroyuki Tsuda
Medium-term bioassay system for detection of carcinogens and modifiers of hepatocarcinogenesis utilizing the GST-P positive liver cell focus as an endpoint marker.
Toxicologic pathology 1989;17(4 Pt 1):630-41.
1989: Hiroyuki Tsuda; T Inoue; Makoto Asamoto; S Fukushima; Nobuyuki Ito; T Okamura; K Ohtaguro; H Washida; K Satoh; Z Amelizad
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach.
Virchows Archiv. B, Cell pathology including molecular pathology 1989;56(5):307-16.
1988: Masao Hirose; A Hagiwara; K Inoue; Nobuyuki Ito; Hideo Kaneko; K Saito; H Matsunaga; N Isobe; A Yoshitake; J Miyamoto
Metabolism of 2- and 3-tert-butyl-4-hydroxyanisole in the rat (III): Metabolites in the urine and feces.
Toxicology 1988;53(1):33-43.
1988: Katsumi Imaida; S Fukushima; K Inoue; T Masui; Masao Hirose; Nobuyuki Ito
Modifying effects of concomitant treatment with butylated hydroxyanisole or butylated hydroxytoluene on N,N-dibutylnitrosamine-induced liver, forestomach and urinary bladder carcinogenesis in F344 male rats.
Cancer letters 1988;43(3):167-72.
1988: Tomoyuki Shirai; Y Tagawa; O Taguchi; E Ikawa; M Mutai; S Fukushima; Nobuyuki Ito
Low tumorigenic response to 3,2'-dimethyl-4-aminobiphenyl administration in the prostate of rats castrated at birth.
Japanese journal of cancer research : Gann 1988;79(12):1293-6.
1988: Masao Hirose; S Fukushima; Y Kurata; Hiroyuki Tsuda; M Tatematsu; Nobuyuki Ito
Modification of N-methyl-N'-nitro-N-nitrosoguanidine-induced forestomach and glandular stomach carcinogenesis by phenolic antioxidants in rats.
Cancer research 1988;48(18):5310-5.
1988: Nobuyuki Ito; Tomoyuki Shirai; Y Tagawa; A Nakamura; S Fukushima
Variation in tumor yield in the prostate and other target organs of the rat in response to varied dosage and duration of administration of 3,2'-dimethyl-4-aminobiphenyl.
Cancer research 1988;48(16):4629-32.
1988: W Thamavit; Malcolm Moore; Y Hiasa; Nobuyuki Ito
Generation of high yields of Syrian hamster cholangiocellular carcinomas and hepatocellular nodules by combined nitrite and aminopyrine administration and Opisthorchis viverrini infection.
Japanese journal of cancer research : Gann 1988;79(8):909-16.
1988: T Masui; S Fukushima; F Katoh; H Yamasaki; Nobuyuki Ito
Effects of sodium L-ascorbate, uracil, butylated hydroxyanisole and extracellular pH on junctional intercellular communication of BALB/c 3T3 cells.
Carcinogenesis 1988;9(7):1143-6.
1988: S Fukushima; Seiko Tamano; M A Shibata; Y Kurata; Masao Hirose; Nobuyuki Ito
The role of urinary pH and sodium ion concentration in the promotion stage of two-stage carcinogenesis of the rat urinary bladder.
Carcinogenesis 1988;9(7):1203-6.
1988: Hiroyuki Tsuda; Makoto Asamoto; M Kagawa; S Uwagawa; K Inoue; M Inui; Nobuyuki Ito
Positive influence of dietary deoxycholic acid on development of pre-neoplastic lesions initiated by N-methyl-N-nitrosourea in rat liver.
Carcinogenesis 1988;9(6):1103-5.
1988: Hiroyuki Tsuda; Makoto Asamoto; Tadashi Ogiso; T Inoue; Nobuyuki Ito; M Nagao
Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion.
Japanese journal of cancer research : Gann 1988;79(6):691-7.
1988: W Thamavit; Malcolm Moore; Y Hiasa; Nobuyuki Ito
Enhancement of DHPN induced hepatocellular, cholangiocellular and pancreatic carcinogenesis by Opisthorchis viverrini infestation in Syrian golden hamsters.
Carcinogenesis 1988;9(6):1095-8.
1988: Nobuyuki Ito; Katsumi Imaida; J L de Camargo; Satoru Takahashi; Makoto Asamoto; Hiroyuki Tsuda
A new medium-term bioassay system for detection of environmental carcinogens using diethylnitrosamine-initiated rat liver followed by D-galactosamine treatment and partial hepatectomy.
Japanese journal of cancer research : Gann 1988;79(5):573-5.
1988: Tomoyuki Shirai; A Masuda; Katsumi Imaida; Tadashi Ogiso; Nobuyuki Ito
Effects of phenobarbital and carbazole on carcinogenesis of the lung, thyroid, kidney, and bladder of rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.
Japanese journal of cancer research : Gann 1988;79(4):460-5.
1988: J Nakanowatari; S Fukushima; Katsumi Imaida; Nobuyuki Ito; S Nagase
Strain differences in N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis in rats.
Japanese journal of cancer research : Gann 1988;79(4):453-9.
1988: Nobuyuki Ito; Katsumi Imaida; Hiroyuki Tsuda; M Shibata; T Aoki; J L de Camargo; S Fukushima
Wide-spectrum initiation models: possible applications to medium-term multiple organ bioassays for carcinogenesis modifiers.
Japanese journal of cancer research : Gann 1988;79(4):413-7.
1988: Hiroyuki Tsuda; M A Moore; Makoto Asamoto; T Inoue; Nobuyuki Ito; K Satoh; A Ichihara; T Nakamura; Z Amelizad; F Oesch
Effect of modifying agents on the phenotypic expression of cytochrome P-450, glutathione S-transferase molecular forms, microsomal epoxide hydrolase, glucose-6-phosphate dehydrogenase and gamma-glutamyltranspeptidase in rat liver preneoplastic lesions.
Carcinogenesis 1988;9(4):547-54.
1988: M Tatematsu; T Aoki; T Inoue; M Mutai; C Furihata; Nobuyuki Ito
Coefficient induction of pepsinogen 1-decreased pyloric glands and gastric cancers in five different strains of rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis 1988;9(3):495-8.
1988: Nobuyuki Ito; Hiroyuki Tsuda; M Tatematsu; T Inoue; Y Tagawa; T Aoki; S Uwagawa; M Kagawa; Tadashi Ogiso; T Masui
Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats--an approach for a new medium-term bioassay system.
Carcinogenesis 1988;9(3):387-94.
1988: T Shirai; K Yamamoto; T Adachi; K Imaida; T Masui; Nobuyuki Ito
Condyloma acuminatum of the bladder in two autopsy cases.
Acta pathologica japonica 1988;38(3):399-405.
1988: M Tatematsu; T Aoki; M Kagawa; Y Mera; Nobuyuki Ito
Reciprocal relationship between development of glutathione S-transferase positive liver foci and proliferation of surrounding hepatocytes in rats.
Carcinogenesis 1988;9(2):221-5.
1988: M Tatematsu; Y Mera; T Inoue; K Satoh; K Sato; Nobuyuki Ito
Stable phenotypic expression of glutathione S-transferase placental type and unstable phenotypic expression of gamma-glutamyltransferase in rat liver preneoplastic and neoplastic lesions.
Carcinogenesis 1988;9(2):215-20.
1988: Seiko Tamano; A Hagiwara; M A Shibata; Y Kurata; S Fukushima; Nobuyuki Ito
Spontaneous tumors in aging (C57BL/6N x C3H/HeN)F1 (B6C3F1) mice.
Toxicologic pathology 1988;16(3):321-6.
1988: M Tatematsu; M Ichinose; K Miki; K Tatematsu; H Kishikawa; Nobuyuki Ito
Gastric phenotypic expression in human gallbladder cancers revealed by pepsinogen immunohistochemistry and mucin histochemistry.
Virchows Archiv. A, Pathological anatomy and histopathology 1988;413(1):25-32.
1988: Masao Hirose; A Masuda; S Fukushima; Nobuyuki Ito
Effects of subsequent antioxidant treatment on 7,12-dimethylbenz[a]anthracene-initiated carcinogenesis of the mammary gland, ear duct and forestomach in Sprague-Dawley rats.
Carcinogenesis 1988;9(1):101-4.
1987: Tomoyuki Shirai; Y Tagawa; S Fukushima; Katsumi Imaida; Nobuyuki Ito
Strong promoting activity of reversible uracil-induced urolithiasis on urinary bladder carcinogenesis in rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Cancer research 1987;47(24 Pt 1):6726-30.
1987: Masao Hirose; A Masuda; Hiroyuki Tsuda; S Uwagawa; Nobuyuki Ito
Enhancement of BHA-induced proliferative rat forestomach lesion development by simultaneous treatment with other antioxidants.
Carcinogenesis 1987;8(11):1731-5.
1987: Masao Hirose; Y Kurata; Hiroyuki Tsuda; S Fukushima; Nobuyuki Ito
Catechol strongly enhances rat stomach carcinogenesis: a possible new environmental stomach carcinogen.
Japanese journal of cancer research : Gann 1987;78(11):1144-9.
1987: Hiroyuki Tsuda; T Masui; E Ikawa; Katsumi Imaida; Nobuyuki Ito
Compared promoting potential of D-galactosamine, carbon tetrachloride and partial hepatectomy in rapid induction of preneoplastic liver lesions in the rat.
Cancer letters 1987;37(2):163-71.
1987: Tomoyuki Shirai; S Fukushima; Masao Hirose; M Ohshima; Nobuyuki Ito
Epithelial lesions of the urinary bladder in three hundred and thirteen autopsy cases.
Japanese journal of cancer research : Gann 1987;78(10):1073-80.
1987: Nobuyuki Ito; Masao Hirose
The role of antioxidants in chemical carcinogenesis.
Japanese journal of cancer research : Gann 1987;78(10):1011-26.
1987: Masao Hirose; T Inoue; A Masuda; Hiroyuki Tsuda; Nobuyuki Ito
Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
Carcinogenesis 1987;8(10):1555-8.
1987: M Tatematsu; S Fukushima; T Aoki; Y Mera; T Inoue; Nobuyuki Ito
Patterns of epithelial proliferation revealed by continuous administration of bromodeoxyuridine during urinary bladder carcinogenesis in rats.
Japanese journal of cancer research : Gann 1987;78(9):879-82.
1987: Hiroyuki Tsuda; M A Moore; Makoto Asamoto; T Inoue; S Fukushima; Nobuyuki Ito; K Satoh; Z Amelizad; F Oesch
Immunohistochemically demonstrated altered expression of cytochrome P-450 molecular forms and epoxide hydrolase in N-ethyl-N-hydroxyethylnitrosamine-induced rat kidney and liver lesions.
Carcinogenesis 1987;8(5):711-7.
1987: M Shibata; Y Kurata; Seiko Tamano; Tadashi Ogiso; S Fukushima; Nobuyuki Ito
13-week subchronic toxicity study with morpholine oleic acid salt administered to B6C3F1 mice.
Journal of toxicology and environmental health 1987;22(2):187-94.
1987: M A Moore; Hiroyuki Tsuda; H J Hacker; K Sato; Peter Bannasch; Nobuyuki Ito
Altered enzyme expression in propylnitrosamine-induced Syrian hamster lung lesions.
Virchows Archiv. B, Cell pathology including molecular pathology 1987;53(5):272-8.