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Hideji Itokawa

Research Profile

Chemicals & Drugs

Living Beings

Phenomena

Magnetic Resonance Spectroscopy

Anatomy

Tumor Cells, Cultured

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Drug Screening Assays, Antitumor

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Publications

TOP 3
Hideji Itokawa; Susan L Morris-Natschke; Toshiyuki Akiyama; Kuo-Hsiung Lee
Plant-derived natural product research aimed at new drug discovery.
An-Shen Lin; Keduo Qian; Yoshihide Usami; Li Lin; Hideji Itokawa; Charleson Hsu; Susan L Morris-Natschke; Kuo-Hsiung Lee
5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix.
Yoshihide Usami; Yi-Nan Liu; An-Shen Lin; Makio Shibano; Toshiyuki Akiyama; Hideji Itokawa; Susan L Morris-Natschke; Kenneth F Bastow; Ryoji Kasai; Kuo-Hsiung Lee
Antitumor agents. 261. 20(S)-protopanaxadiol and 20(s)-protopanaxatriol as antiangiogenic agents and total assignment of (1)H NMR spectra.

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All Publications

2008: Hideji Itokawa; Susan L Morris-Natschke; Toshiyuki Akiyama; Kuo-Hsiung Lee
Plant-derived natural product research aimed at new drug discovery.
Journal of natural medicines 2008;62(3):263-80.
2008: An-Shen Lin; Keduo Qian; Yoshihide Usami; Li Lin; Hideji Itokawa; Charleson Hsu; Susan L Morris-Natschke; Kuo-Hsiung Lee
5-Hydroxymethyl-2-furfural, a clinical trials agent for sickle cell anemia, and its mono/di-glucosides from classically processed steamed Rehmanniae Radix.
Journal of natural medicines 2008;62(2):164-7.
2008: Yoshihide Usami; Yi-Nan Liu; An-Shen Lin; Makio Shibano; Toshiyuki Akiyama; Hideji Itokawa; Susan L Morris-Natschke; Kenneth F Bastow; Ryoji Kasai; Kuo-Hsiung Lee
Antitumor agents. 261. 20(S)-protopanaxadiol and 20(s)-protopanaxatriol as antiangiogenic agents and total assignment of (1)H NMR spectra.
Journal of natural products 2008;71(3):478-81.
2008: Hideji Itokawa; Qian Shi; Toshiyuki Akiyama; Susan L Morris-Natschke; Kuo-Hsiung Lee
Recent advances in the investigation of curcuminoids.
Chinese medicine 2008;3():11.
2007: Jin Tatsuzaki; Masahiko Taniguchi; Kenneth F Bastow; Kyoko Goto; Susan L Morris-Natschke; Hideji Itokawa; Kimiye Baba; Kuo-Hsiung Lee
Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.
Bioorganic & medicinal chemistry 2007;15(18):6193-9.
2007: Makio Shibano; An-Shen Lin; Hideji Itokawa; Kuo-Hsiung Lee
Separation and characterization of active flavonolignans of Silybum marianum by liquid chromatography connected with hybrid ion-trap and time-of-flight mass spectrometry (LC-MS/IT-TOF).
Journal of natural products 2007;70(9):1424-8.
2006: Jin Tatsuzaki; Kenneth F Bastow; Kyoko Goto; Seiko Nakamura; Hideji Itokawa; Kuo-Hsiung Lee
Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents.
Journal of natural products 2006;69(10):1445-9.
2006: Hiroshi Morita; Michiko Eda; Toru Iizuka; Yusuke Hirasawa; Mitsuhiro Sekiguchi; Young Sook Yun; Hideji Itokawa; Koichi Takeya
Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis.
Bioorganic & medicinal chemistry letters 2006;16(17):4458-61.
2006: Hiroshi Morita; Toru Iizuka; Akira Gonda; Hideji Itokawa; Koichi Takeya
Cycloleonuripeptides E and F, cyclic nonapeptides from Leonurus heterophyllus.
Journal of natural products 2006;69(5):839-41.
2005: Hiroshi Morita; Toru Iizuka; Chee Yan Choo; Kit-Lam Chan; Hideji Itokawa; Koichi Takeya
Dichotomins J and K, vasodilator cyclic peptides from Stellaria dichotoma.
Journal of natural products 2005;68(11):1686-8.
2005: Hiroshi Morita; Khalijah Awang; A Hamid A Hadi; Koichi Takeya; Hideji Itokawa; Jun'ichi Kobayashi
Conformational analysis of rhazinilam and three-dimensional quantitative structure-activity relationships of rhazinilam analogues.
Bioorganic & medicinal chemistry letters 2005;15(4):1045-50.
2004: Osamu Shirota; Setsuko Sekita; Motoyoshi Satake; Hiroshi Morita; Koichi Takeya; Hideji Itokawa
Nine new isoxuxuarine-type triterpene dimers from Maytenus chuchuhuasca.
Chemistry & biodiversity 2004;1(9):1296-307.
2004: Osamu Shirota; Setsuko Sekita; Motoyoshi Satake; Hiroshi Morita; Koichi Takeya; Hideji Itokawa
Two cangorosin A type triterpene dimers from Maytenus chuchuhuasca.
Chemical & pharmaceutical bulletin 2004;52(9):1148-50.
2004: Osamu Shirota; Setsuko Sekita; Motoyoshi Satake; Hiroshi Morita; Koichi Takeya; Hideji Itokawa
Nine regioisomeric and stereoisomeric triterpene dimers from Maytenus chuchuhuasca.
Chemical & pharmaceutical bulletin 2004;52(6):739-46.
2004: Nobuko Sakurai; Jiu-Hong Wu; Yutaka Sashida; Yoshihiro Mimaki; Tamotsu Nikaido; Kazuo Koike; Hideji Itokawa; Kuo-Hsiung Lee
Anti-AIDS agents. Part 57: Actein, an anti-HIV principle from the rhizome of Cimicifuga racemosa (black cohosh), and the anti-HIV activity of related saponins.
Bioorganic & medicinal chemistry letters 2004;14(5):1329-32.
2004: Yukio Hitotsuyanagi; Tomoyo Hasuda; Takayuki Aihara; Hiroshi Ishikawa; Kentaro Yamaguchi; Hideji Itokawa; Koichi Takeya
Synthesis of [Gly-1]RA-VII, [Gly-2]RA-VII, and [Gly-4]RA-VII. Glycine-containing analogues of RA-VII, an antitumor bicyclic hexapeptide from Rubia plants.
The Journal of organic chemistry 2004;69(5):1481-6.
2003: Hironori Ohtsu; Hideji Itokawa; Zhiyan Xiao; Ching-Yuan Su; Charles C-Y Shih; Tzuying Chiang; Eugene Chang; YiFen Lee; Shang Yi Chiu; Chawnshang Chang; Kuo-Hsiung Lee
Antitumor agents 222. Synthesis and anti-androgen activity of new diarylheptanoids.
Bioorganic & medicinal chemistry 2003;11(23):5083-90.
2003: Yukio Hitotsuyanagi; Shin-Ichi Sasaki; Yuji Matsumoto; Kentaro Yamaguchi; Hideji Itokawa; Koichi Takeya
Synthesis of [L-Ala-1]RA-VII, [D-Ala-2]RA-VII, and [D-Ala-4]RA-VII by epimerization of RA-VII, an antitumor bicyclic hexapeptide from Rubia plants, through oxazoles.
Journal of the American Chemical Society 2003;125(24):7284-90.
2002: Yoshiaki Kamano; Ayano Yamashita; Toshihiko Nogawa; Hiroshi Morita; Koichi Takeya; Hideji Itokawa; Toshiaki Segawa; Ayako Yukita; Kyoko Saito; Mariko Katsuyama; George R Pettit
QSAR evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/5(1).
Journal of medicinal chemistry 2002;45(25):5440-7.
2002: Hironori Ohtsu; Zhiyan Xiao; Junko Ishida; Masahiro Nagai; Hui-Kang Wang; Hideji Itokawa; Ching-Yuan Su; Charles Shih; Tzuying Chiang; Eugene Chang; YiFen Lee; Meng-Yin Tsai; Chawnshang Chang; Kuo-Hsiung Lee
Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.
Journal of medicinal chemistry 2002;45(23):5037-42.
2002: Junko Ishida; Hironori Ohtsu; Yoko Tachibana; Yuka Nakanishi; Kenneth F Bastow; Masahiro Nagai; Hui-Kang Wang; Hideji Itokawa; Kuo-Hsiung Lee
Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents.
Bioorganic & medicinal chemistry 2002;10(11):3481-7.
2001: Yukio Hitotsuyanagi; A Ozeki; Hideji Itokawa; S de Mello Alves; Koichi Takeya
Cedronolactone E, a novel C(19) quassinoid from Simaba cedron.
Journal of natural products 2001;64(12):1583-4.
2001: Lallan Mishra; R Sinha; Hideji Itokawa; Kenneth F Bastow; Y Tachibana; Y Nakanishi; N Kilgore; Kuo-Hsiung Lee
Anti-HIV and cytotoxic activities of Ru(II)/Ru(III) polypyridyl complexes containing 2,6-(2'-benzimidazolyl)-pyridine/chalcone as co-ligand.
Bioorganic & medicinal chemistry 2001;9(7):1667-71.
2001: T Matsumoto; A Shishido; H Morita; Hideji Itokawa; Koichi Takeya
Cyclolinopeptides F-I, cyclic peptides from linseed.
Phytochemistry 2001;57(2):251-60.
2001: Chee Yan Choo; Kit-Lam Chan; Koichi Takeya; Hideji Itokawa
Cytotoxic activity of Typhonium flagelliforme (Araceae).
Phytotherapy research : PTR 2001;15(3):260-2.
2000: M Haraguchi; Y Mimaki; M Motidome; H Morita; Koichi Takeya; Hideji Itokawa; A Yokosuka; Y Sashida
Steroidal saponins from the leaves of Cestrum sendtenerianum.
Phytochemistry 2000;55(7):715-20.
2000: Hiroshi Morita; Yoshihiro Sato; Kit-Lam Chan; Chee Yan Choo; Hideji Itokawa; Koichi Takeya; Jun'ichi Kobayashi
Samoquasine A, a benzoquinazoline alkaloid from the seeds of Annona squamosa.
Journal of natural products 2000;63(12):1707-8.
2000: Yukio Hitotsuyanagi; M Fukuyo; K Tsuda; M Kobayashi; A Ozeki; Hideji Itokawa; Koichi Takeya
4-Aza-2,3-dehydro-4-deoxypodophyllotoxins: simple aza-podophyllotoxin analogues possessing potent cytotoxicity.
Bioorganic & medicinal chemistry letters 2000;10(4):315-7.
1999: Hideji Itokawa; Koichi Takeya; Yukio Hitotsuyanagi; H Morita
[Antitumor compounds isolated from higher plants].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1999;119(8):529-83.
1998: Kit-Lam Chan; Chee Yan Choo; H Morita; Hideji Itokawa
High performance liquid chromatography in phytochemical analysis of Eurycoma longifolia.
Planta medica 1998;64(8):741-5.
1998: Yoshiaki Kamano; A Kotake; H Hashima; M Inoue; H Morita; Koichi Takeya; Hideji Itokawa; N Nandachi; T Segawa; A Yukita; K Saitou; M Katsuyama; George R Pettit
Structure-cytotoxic activity relationship for the toad poison bufadienolides.
Bioorganic & medicinal chemistry 1998;6(7):1103-15.
1998: A Ozeki; Yukio Hitotsuyanagi; E Hashimoto; Hideji Itokawa; Koichi Takeya; S de Mello Alves
Cytotoxic quassinoids from Simaba cedron.
Journal of natural products 1998;61(6):776-80.
1998: H Morita; Akira Gonda; L Wei; Y Yamamura; H Wakabayashi; K Takeya; Hideji Itokawa
Four new taxoids from Taxus cuspidata var. nana.
Planta medica 1998;64(2):183-6.
1998: Y S Yun; K Shimizu; H Morita; Koichi Takeya; Hideji Itokawa; Osamu Shirota
Triterpenoid saponin from Vaccaria segetalis.
Phytochemistry 1998;47(1):143-4.
1997: H Morita; Y S Yun; Koichi Takeya; Hideji Itokawa
Conformational preference for segetalins G and H, cyclic peptides with estrogen-like activity from seeds of Vaccaria segetalis.
Bioorganic & medicinal chemistry 1997;5(11):2063-7.
1997: C Hirobe; Z S Qiao; Koichi Takeya; Hideji Itokawa
Cytotoxic flavonoids from Vitex agnus-castus.
Phytochemistry 1997;46(3):521-4.
1997: H Morita; Koichi Takeya; Hideji Itokawa
Cyclic octapeptides from Stellaria dichotoma var. lanceolata.
Phytochemistry 1997;45(4):841-5.
1997: Hiroshi Morita; Akira Gonda; L Wei; Y Yamamura; Koichi Takeya; Hideji Itokawa
Taxuspinananes A and B, new taxoids from Taxus cuspidata var. nana.
Journal of natural products 1997;60(4):390-2.
1997: Y S Yun; Hiroshi Morita; Koichi Takeya; Hideji Itokawa
Cyclic peptides from higher plants. 34. Segetalins G and H, structures and estrogen-like activity of cyclic pentapeptides from Vaccaria segetalis.
Journal of natural products 1997;60(3):216-8.
1997: H Morita; Y S Yun; Koichi Takeya; Hideji Itokawa; Osamu Shirota
Thionation of segetalins A and B, cyclic peptides with estrogen-like activity from seeds of Vaccaria segetalis.
Bioorganic & medicinal chemistry 1997;5(3):631-6.
1997: Hidekazu Nagaya; Yoneko Tobita; T Nagae; Hideji Itokawa; Koichi Takeya; A F Halim; Osama B Abdel-Halim
Cytotoxic triterpenes from Cleome africana.
Phytochemistry 1997;44(6):1115-9.
1997: Ichiro Takano; Ichiro Yasuda; M Nishijima; Y Yanagi; Koichi Takeya; Hideji Itokawa
Ester-type cephalotaxus alkaloids from Cephalotaxus harringtonia var. drupacea.
Phytochemistry 1997;44(4):735-8.
1996: H Morita; T Kayashita; Koichi Takeya; Hideji Itokawa
Conformational analysis of a cyclic heptapeptide, pseudostellarin D by molecular dynamics and Monte Carlo simulations.
Chemical & pharmaceutical bulletin 1996;44(11):2177-80.
1996: K Osawa; H Yasuda; H Morita; K Takeya; Hideji Itokawa
Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus.
Journal of natural products 1996;59(9):823-7.
1996: Koichi Takeya; Z S Quio; C Hirobe; Hideji Itokawa
Cytotoxic trichilin-type limonoids from Melia azedarach.
Bioorganic & medicinal chemistry 1996;4(8):1355-9.
1996: A A el-Gamal; Koichi Takeya; Hideji Itokawa; A F Halim; M M Amer; H E Saad; S A Awad
Anthraquinones from the polar fractions of Galium sinaicum.
Phytochemistry 1996;42(4):1149-55.
1996: Koichi Takeya; Z S Qiao; C Hirobe; Hideji Itokawa
Cytotoxic azadirachtin-type limonoids from Melia azedarach.
Phytochemistry 1996;42(3):709-12.
1996: H Morita; S Nagashima; Y Uchiumi; O Kuroki; Koichi Takeya; Hideji Itokawa
Cyclic peptides from higher plants. XXVIII. Antitumor activity and hepatic microsomal biotransformation of cyclic pentapeptides, astins, from Aster tataricus.
Chemical & pharmaceutical bulletin 1996;44(5):1026-32.
1996: H Morita; Y S Yun; Koichi Takeya; Hideji Itokawa; Osamu Shirota
A cyclic heptapeptide from Vaccaria segetalis.
Phytochemistry 1996;42(2):439-41.
1996: H M Sirat; A A Rahman; Hideji Itokawa; H Morita
Constituents of the rhizomes of two Alpinia species of Malaysia.
Planta medica 1996;62(2):188-9.
1996: Hiroshi Morita; T Kayashita; M Shimomura; Koichi Takeya; Hideji Itokawa
Cyclic peptides from higher plants. 24.1 yunnanin C, a novel cyclic heptapeptide from Stellaria yunnanensis.
Journal of natural products 1996;59(3):280-2.
1995: Hideji Itokawa; Y Yun; H Morita; Koichi Takeya; K Yamada
Estrogen-like activity of cyclic peptides from Vaccaria segetalis extracts.
Planta medica 1995;61(6):561-2.
1995: Y Kamano; H P Zhang; A Hino; M Yoshida; George R Pettit; C L Herald; Hideji Itokawa
An improved source of bryostatin 10, Bugula neritina from the Gulf of Aomori, Japan.
Journal of natural products 1995;58(12):1868-75.
1995: L Mishra; M K Said; Hideji Itokawa; K Takeya
Antitumor and antimicrobial activities of Fe(II)/Fe(III) complexes derived from some heterocyclic compounds.
Bioorganic & medicinal chemistry 1995;3(9):1241-5.
1995: K Osawa; H Yasuda; H Morita; K Takeya; Hideji Itokawa
Eucalyptone from Eucalyptus globulus.
Phytochemistry 1995;40(1):183-4.
1995: H Morita; S Nagashima; Koichi Takeya; Hideji Itokawa
Solution forms of antitumor cyclic pentapeptides with 3,4-dichlorinated proline residues, astins A and C, from Aster tataricus.
Chemical & pharmaceutical bulletin 1995;43(8):1395-7.
1995: Hideji Itokawa; Z S Qiao; C Hirobe; Koichi Takeya
Cytotoxic limonoids and tetranortriterpenoids from Melia azedarach.
Chemical & pharmaceutical bulletin 1995;43(7):1171-5.
1995: Hiroshi Morita; T Kayashita; Koichi Takeya; Hideji Itokawa
Cyclic peptides from higher plants, Part 15. Pseudostellarin H, a new cyclic octapeptide from Pseudostellaria heterophylla.
Journal of natural products 1995;58(6):943-7.
1995: H Morita; S Nagashima; Koichi Takeya; Hideji Itokawa
Structure of a new peptide, astin J, from Aster tataricus.
Chemical & pharmaceutical bulletin 1995;43(2):271-3.
1994: Osamu Shirota; H Morita; Koichi Takeya; Hideji Itokawa
Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus chuchuhuasca.
Journal of natural products 1994;57(12):1675-81.
1994: K Osawa; H Yasuda; T Maruyama; H Morita; K Takeya; Hideji Itokawa
Antibacterial trichorabdal diterpenes from Rabdosia trichocarpa.
Phytochemistry 1994;36(5):1287-91.
1994: K Osawa; H Yasuda; T Maruyama; H Morita; K Takeya; Hideji Itokawa; K Okuda
An investigation of diterpenes from the leaves of Rabdosia trichocarpa and their antibacterial activity against oral microorganisms.
Chemical & pharmaceutical bulletin 1994;42(4):922-5.
1994: Hideji Itokawa; T Miyashita; H Morita; Koichi Takeya; T Hirano; M Homma; K Oka
Structural and conformational studies of [Ile7] and [Leu7]surfactins from Bacillus subtilis natto.
Chemical & pharmaceutical bulletin 1994;42(3):604-7.
1993: Hideji Itokawa; Z Z Ibraheim; Y F Qiao; Koichi Takeya
Anthraquinones, naphthohydroquinones and naphthohydroquinone dimers from Rubia cordifolia and their cytotoxic activity.
Chemical & pharmaceutical bulletin 1993;41(10):1869-72.
1993: H Morita; K Matsumoto; Koichi Takeya; Hideji Itokawa
Conformation of tropolone ring in antileukemic tropoloisoquinoline alkaloids.
Chemical & pharmaceutical bulletin 1993;41(8):1478-80.
1993: H Morita; K Matsumoto; Koichi Takeya; Hideji Itokawa; Y Iitaka
Structures and solid state tautomeric forms of two novel antileukemic tropoloisoquinoline alkaloids, pareirubrines A and B, from Cissampelos pareira.
Chemical & pharmaceutical bulletin 1993;41(8):1418-22.
1993: Hideji Itokawa; K Kondo; Yukio Hitotsuyanagi; M Isomura; Koichi Takeya
Studies on RA derivatives. V. Synthesis and antitumor activity of Ala2-modified RA-VII derivatives.
Chemical & pharmaceutical bulletin 1993;41(8):1402-10.
1993: Hideji Itokawa; K Kondo; Yukio Hitotsuyanagi; A Nakamura; H Morita; Koichi Takeya
Preparation and cytotoxicity of cyclic hexapeptides, RA derivatives.
Chemical & pharmaceutical bulletin 1993;41(7):1266-9.
1993: Hideji Itokawa; K Masuyama; H Morita; Koichi Takeya
Cytotoxic sesquiterpenes from Nardostachys chinensis.
Chemical & pharmaceutical bulletin 1993;41(6):1183-4.
1993: Koichi Takeya; T Yamamiya; H Morita; Hideji Itokawa
Two antitumour bicyclic hexapeptides from Rubia cordifolia.
Phytochemistry 1993;33(3):613-5.
1993: H Morita; S Nagashima; Koichi Takeya; Hideji Itokawa
Astins A and B, antitumor cyclic pentapeptides from Aster tataricus.
Chemical & pharmaceutical bulletin 1993;41(5):992-3.
1993: K Oka; T Hirano; M Homma; H Ishii; K Murakami; S Mogami; A Motizuki; H Morita; Koichi Takeya; Hideji Itokawa
Satisfactory separation and MS-MS spectrometry of six surfactins isolated from Bacillus subtilis natto.
Chemical & pharmaceutical bulletin 1993;41(5):1000-2.
1993: H Morita; T Yamamiya; Koichi Takeya; Hideji Itokawa; Chiseko Sakuma; J Yamada; T Suga
Conformational recognition of RA-XII by 80S ribosomes: a differential line broadening study in 1H NMR spectroscopy.
Chemical & pharmaceutical bulletin 1993;41(4):781-3.
1992: Y Ichihara; Koichi Takeya; Yukio Hitotsuyanagi; H Morita; S Okuyama; M Suganuma; H Fujiki; M Motidome; Hideji Itokawa
Cajucarinolide and isocajucarinolide: anti-inflammatory diterpenes from Croton cajucara.
Planta medica 1992;58(6):549-51.
1992: S Uehara; I Yasuda; K Takeya; Hideji Itokawa
[Terpenoids and curcuminoids of the rhizoma of Curcuma xanthorrhiza Roxb].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1992;112(11):817-23.
1992: Hideji Itokawa; K Saitou; H Morita; Koichi Takeya; K Yamada
Structures and conformations of metabolites of antitumor cyclic hexapeptides, RA-VII and RA-X.
Chemical & pharmaceutical bulletin 1992;40(11):2984-9.
1992: K Osawa; H Yasuda; T Maruyama; H Morita; K Takeya; Hideji Itokawa
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria.
Chemical & pharmaceutical bulletin 1992;40(11):2970-4.
1992: K Nishiya; T Kimura; K Takeya; Hideji Itokawa
Sesquiterpenoids and iridoid glycosides from Valeriana fauriei.
Phytochemistry 1992;31(10):3511-4.
1992: H Morita; T Yamamiya; Koichi Takeya; Hideji Itokawa
New antitumor bicyclic hexapeptides, RA-XI, -XII, -XIII and -XIV from Rubia cordifolia.
Chemical & pharmaceutical bulletin 1992;40(5):1352-4.
1992: Hideji Itokawa; H Morita; Koichi Takeya
Solution forms of an antitumor cyclic hexapeptide, RA-VII in dimethyl sulfoxide-d6 from nuclear magnetic resonance studies.
Chemical & pharmaceutical bulletin 1992;40(4):1050-2.
1991: Hideji Itokawa; K Saitou; H Morita; Koichi Takeya
Conformational analysis of [n-demethyl-Tyr(OCH3)-3]RA-VII, conformationally restricted model approach.
Chemical & pharmaceutical bulletin 1991;39(8):2161-3.
1991: Hideji Itokawa; Y Ichihara; M Mochizuki; T Enomori; H Morita; Osamu Shirota; M Inamatsu; Koichi Takeya
A cytotoxic substance from Sangre de Grado.
Chemical & pharmaceutical bulletin 1991;39(4):1041-2.
1991: H Morita; M Nakayama; H Kojima; Koichi Takeya; Hideji Itokawa; E P Schenkel; M Motidome
Structures and cytotoxic activity relationship of casearins, new clerodane diterpenes from Casearia sylvestris Sw.
Chemical & pharmaceutical bulletin 1991;39(3):693-7.
1990: Hideji Itokawa; N Totsuka; H Morita; Koichi Takeya; Y Iitaka; E P Schenkel; M Motidome
New antitumor principles, casearins A-F, for Casearia sylvestris Sw. (Flacourtiaceae).
Chemical & pharmaceutical bulletin 1990;38(12):3384-8.
1989: T Fukunaga; T Ide; M Yamashiro; K Takeya; Hideji Itokawa
[Studies on pharmacological activity of the Japanese and European mistletoe].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1989;109(8):600-5.
1989: H Morita; Y Ichihara; K Takeya; K Watanabe; Hideji Itokawa; M Motidome
A New Indole Alkaloid Glycoside from the Leaves of Palicourea marcgravii.
Planta medica 1989;55(3):288-9.
1989: Hideji Itokawa; N Totsuka; K Nakahara; M Maezuru; Koichi Takeya; M Kondo; M Inamatsu; H Morita
A quantitative structure-activity relationship for antitumor activity of long-chain phenols from Ginkgo biloba L.
Chemical & pharmaceutical bulletin 1989;37(6):1619-21.
1989: T Fukunaga; K Nishiya; I Kajikawa; K Takeya; Hideji Itokawa
Studies on the constituents of Japanese mistletoes from different host trees, and their antimicrobial and hypotensive properties.
Chemical & pharmaceutical bulletin 1989;37(6):1543-6.
1989: Hideji Itokawa; Y Ichihara; K Watanabe; K Takeya
An antitumor principle from Euphorbia lathyris.
Planta medica 1989;55(3):271-2.
1988: Hideji Itokawa; J P Xu; K Takeya
Studies on chemical constituents of antitumor fraction from Periploca sepium. V. Structures of new pregnane glycosides, periplocosides J, K, F and O.
Chemical & pharmaceutical bulletin 1988;36(11):4441-6.
1988: Hideji Itokawa
[Research on antineoplastic drugs from natural sources. Especially from higher plants].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1988;108(9):824-41.
1988: Hideji Itokawa; H Morita; I Katou; Koichi Takeya; A J Cavalheiro; R C de Oliveira; M Ishige; M Motidome
Cytotoxic diterpenes from the rhizomes of Hedychium coronarium.
Planta medica 1988;54(4):311-5.
1988: Hideji Itokawa; H Morita; Koichi Takeya; M Motidome
Diterpenes from rhizomes of Hedychium coronarium.
Chemical & pharmaceutical bulletin 1988;36(7):2682-4.
1988: Hideji Itokawa; J P Xu; K Takeya
Studies on chemical constituents of antitumor fraction from Periploca sepium. IV. Structures of new pregnane glycosides, periplocosides D, E, L, and M.
Chemical & pharmaceutical bulletin 1988;36(6):2084-9.
1988: Hideji Itokawa; N Totsuka; Koichi Takeya; K Watanabe; E Obata
Antitumor principles from Casearia sylvestris Sw. (Flacourtiaceae), structure elucidation of new clerodane diterpenes by 2-D NMR spectroscopy.
Chemical & pharmaceutical bulletin 1988;36(4):1585-8.
1988: H Morita; Hideji Itokawa
Cytotoxic and antifungal diterpenes from the seeds of Alpinia galanga.
Planta medica 1988;54(2):117-20.
1988: Hideji Itokawa; J Xu; K Takeya; K Watanabe; J Shoji
Studies on chemical constituents of antitumor fraction from Periploca sepium. II. Structures of new pregnane glycosides, periplocosides A, B and C.
Chemical & pharmaceutical bulletin 1988;36(3):982-7.
1987: Hideji Itokawa; J P Xu; K Takeya
Studies on chemical constituents of antitumor fraction from Periploca sepium BGE. I.
Chemical & pharmaceutical bulletin 1987;35(11):4524-9.
1987: Hideji Itokawa; N Totsuka; K Nakahara; Koichi Takeya; Jean-Pierre Lepoittevin; Y Asakawa
Antitumor principles from Ginkgo biloba L.
Chemical & pharmaceutical bulletin 1987;35(7):3016-20.
1987: Hideji Itokawa; K Mizuno; Y Ichihara; K Takeya
Isolation and 13C-NMR Studies on Three New Furanoditerpenyl Glucosides from Jateorrhiza columba.
Planta medica 1987;53(3):271-3.
1987: Hideji Itokawa; S Tsuruoka; K Takeya; N Mori; T Sonobe; S Kosemura; T Hamanaka
An antitumor morphinane alkaloid, sinococuline, from Cocculus trilobus.
Chemical & pharmaceutical bulletin 1987;35(4):1660-2.
1987: Hideji Itokawa; H Morita; T Sumitomo; N Totsuka; Koichi Takeya
Antitumour principles from Alpinia galanga.
Planta medica 1987;53(1):32-3.
1986: Hideji Itokawa; K Takeya; N Mori; T Sonobe; S Mihashi; T Hamanaka
Studies on antitumor cyclic hexapeptides RA obtained from rubiae radix, rubiaceae. VI. Minor antitumor constituents.
Chemical & pharmaceutical bulletin 1986;34(9):3762-8.
1985: H Hikino; Y Kiso; N Kato; Y Hamada; T Shioiri; R Aiyama; Hideji Itokawa; F Kiuchi; U Sankawa
Antihepatotoxic actions of gingerols and diarylheptanoids.
Journal of ethnopharmacology 1985;14(1):31-9.
1985: Hideji Itokawa; F Hirayama; K Funakoshi; K Takeya
Studies on the antitumor bisabolane sesquiterpenoids isolated from Curcuma xanthorrhiza.
Chemical & pharmaceutical bulletin 1985;33(8):3488-92.
1984: Hideji Itokawa; K Takeya; N Mori; M Takanashi; H Yamamoto; T Sonobe; S Kidokoro
Cell growth-inhibitory effects of derivatives of antitumor cyclic hexapeptide RA-V obtained from Rubiae radix (V).
Gann = Gan 1984;75(10):929-36.
1984: Hideji Itokawa; T Oshima; H Matsumoto; S Mihashi
[Synthesis of alpha-alkylidene-gamma-butyrolactones].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1984;104(8):839-47.
1984: Hideji Itokawa; K Takeya; N Mori; T Sonobe; N Serisawa; T Hamanaka; S Mihashi
Studies on antitumor cyclic hexapeptides RA obtained from Rubiae Radix, Rubiaceae. III. On derivatives of RA-V and their in vivo activities.
Chemical & pharmaceutical bulletin 1984;32(8):3216-26.
1984: Hideji Itokawa; K Takeya; N Mori; S Kidokoro; H Yamamoto
Studies on antitumour cyclic hexapeptides RA obtained from Rubiae radix, Rubiaceae (IV): Quantitative determination of RA-VII and RA-V in commercial Rubiae radix and collected plants.
Planta medica 1984;50(4):313-6.
1984: Hideji Itokawa; K Takeya; N Mori; T Hamanaka; T Sonobe; K Mihara
Isolation and antitumor activity of cyclic hexapeptides isolated from Rubiae radix.
Chemical & pharmaceutical bulletin 1984;32(1):284-90.
1983: Hideji Itokawa; K Takeya; K Mihara; N Mori; T Hamanaka; T Sonobe; Y Iitaka
Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix.
Chemical & pharmaceutical bulletin 1983;31(4):1424-7.
1977: K Takeya; Hideji Itokawa
Stereochemistry in oxidation of allylic alcohols by cell-free system of callus induced from Cannabis sativa L.
Chemical & pharmaceutical bulletin 1977;25(8):1947-51.
1977: Hideji Itokawa; K Takeya; S Mihashi
Biotransformation of cannabinoid precursors and related alcohols by suspension cultures of callus induced from Cannabis sativa L.
Chemical & pharmaceutical bulletin 1977;25(8):1941-6.
1976: Hideji Itokawa; K Takeya; M Akasu
Stereochemistry in oxidation of primary allylic alcohols by cell-free system of callus induced from Cannabis saliva L.
Chemical & pharmaceutical bulletin 1976;24(7):1681-3.