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Michael Axthelm

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Haesun Park; Michael Piatak; Louis J Picker; Andrew W Sylwester; Lauren Adamson; Michael K Axthelm; Tae Ha; Shoko I Hagen; Alfred Legasse; Jeffrey D Lifson; Juliana M McElrath; Karl Mullen; Arys Nogueron; Robert A Seder
Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV Gag protein-induced T cell responses in nonhuman primates.
Nathan J Weyand; Scott W Wong; Nyiawung A Taku; Anne M Wertheimer; Michael K Axthelm; Nicolas Biais; Lewis M Brown; Susan Clary; Lindsay D Gregston; Dustin L Higashi; Theodore R Hobbs; Alfred W Legasse; Shannon Planer; Jennifer L Sisko; Magdalene So
Neisseria infection of rhesus macaques as a model to study colonization, transmission, persistence, and horizontal gene transfer.
Ryan D Estep; Scott G Hansen; Kelsey S Rogers; Michael K Axthelm; Scott W Wong
Genomic characterization of Japanese macaque rhadinovirus, a novel herpesvirus isolated from a nonhuman primate with a spontaneous inflammatory demyelinating disease.

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All Publications

2013: Haesun Park; Michael Piatak; Louis J Picker; Andrew W Sylwester; Lauren Adamson; Michael K Axthelm; Tae Ha; Shoko I Hagen; Alfred Legasse; Jeffrey D Lifson; Juliana M McElrath; Karl Mullen; Arys Nogueron; Robert A Seder
Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV Gag protein-induced T cell responses in nonhuman primates.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(8):4103-15.
2013: Nathan J Weyand; Scott W Wong; Nyiawung A Taku; Anne M Wertheimer; Michael K Axthelm; Nicolas Biais; Lewis M Brown; Susan Clary; Lindsay D Gregston; Dustin L Higashi; Theodore R Hobbs; Alfred W Legasse; Shannon Planer; Jennifer L Sisko; Magdalene So
Neisseria infection of rhesus macaques as a model to study colonization, transmission, persistence, and horizontal gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):3059-64.
2013: Ryan D Estep; Scott G Hansen; Kelsey S Rogers; Michael K Axthelm; Scott W Wong
Genomic characterization of Japanese macaque rhadinovirus, a novel herpesvirus isolated from a nonhuman primate with a spontaneous inflammatory demyelinating disease.
Journal of virology 2013;87(1):512-23.
2012: Yoshinori Fukazawa; Shoko I Hagen; Scott G Hansen; Francois Lefebvre; Alfred W Legasse; Yuan Li; Jeffrey D Lifson; Richard Lum; Eisa Mahyari; Adrian McDermott; David C Montefiori; Kelli Oswald; Haesun Park; Michael Piatak; Michael K Axthelm; Jin Young Bae; Mark J Cameron; Noel Coombes; Paul T Edlefsen; Guido Ferrari; Rafick P Sékaly; Rebecca Shoemaker; Andrew T Smith; Petra Stafova; Tonya Swanson; Andrew Sylwester; Marcelo Delos Reyes; Louis J Picker
Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.
Nature medicine 2012;18(11):1673-81.
2012: Afam A Okoye; Byung S Park; Audrie Pattenn; Christopher Pexton; Michael Piatak; Chike Abana; Michael K Axthelm; Alfred Legasse; Jeffrey D Lifson; Richard Lum; Shannon Planer; Matthew Reyes; Mukta Rohankhedkar; Andrew W Sylwester; Louis J Picker
Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection.
The Journal of experimental medicine 2012;209(4):641-51.
2012: Bridget A Robinson; Michael K Axthelm; Victor DeFilippis; Flora Engelmann; Ryan D Estep; Richard Grant; He Li; Ilhem Messaoudi; Megan A O'Connor; Britt Poland; Scott W Wong
Viral interferon regulatory factors are critical for delay of the host immune response against rhesus macaque rhadinovirus infection.
Journal of virology 2012;86(5):2769-79.
2011: Ryan D Estep; John M Jones; Alfred Legasse; Helen Li; Minsha Manoharan; Ilhem Messaoudi; Megan A O'Connor; Beata U Orzechowska; Shannon Planer; Michael F Powers; Bridget A Robinson; Jerald Sprague; Jennifer Wilk; Michael K Axthelm; Alexander Barron; Flora Engelmann; Bonnie Yen; Scott W Wong
Deletion of the monkeypox virus inhibitor of complement enzymes locus impacts the adaptive immune response to monkeypox virus in a nonhuman primate model of infection.
Journal of virology 2011;85(18):9527-42.
2011: Michael K Axthelm; Dennis N Bourdette; Steven G Kohama; Minsha Manoharan; Gail H Marracci; Elizabeth T Mullaney; Jim Pollaro; William D Rooney; Larry S Sherman; Weiping Su; Paul Wang; Ellen Witkowski; Scott W Wong
Japanese macaque encephalomyelitis: a spontaneous multiple sclerosis-like disease in a nonhuman primate.
Annals of neurology 2011;70(3):362-73.
2011: Luka Cicin-Sain; Noreen Currier; Miranda B Fischer; Shoko I Hagen; Caroline W Koudelka; Alfred W Legasse; Janko Nikolich-Zugich; Don C Siess; Andrew W Sylwester; Michael K Axthelm; Louis J Picker
Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1722-32.
2011: Scott G Hansen; Julia C Ford; Matthew S Lewis; Abigail B Ventura; Colette M Hughes; Lia Coyne-Johnson; Nathan Whizin; Kelli Oswald; Rebecca Shoemaker; Tonya Swanson; Alfred W Legasse; Maria J Chiuchiolo; Christopher L Parks; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Michael Piatak; Jeffrey D Lifson; Louis J Picker
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine.
Nature 2011;473(7348):523-7.
2010: Amanda Leone; Mukta Rohankhedkar; Afam Okoye; Alfred Legasse; Michael K Axthelm; Francios VILLINGER; Michael Piatak; Jeffrey D Lifson; Brigitte Assouline; Michel Morre; Louis J Picker; Donald L Sodora
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(3):1650-9.
2010: Luka Cicin-Sain; Susan Smyk-Pearson; Sue Smyk-Paerson; Noreen Currier; Laura Byrd; Caroline Koudelka; Tammie Robinson; Gwendolyn Swarbrick; Shane Tackitt; Alfred Legasse; Miranda Fischer; Dragana Nikolich-Zugich; Byung S Park; Theodore R Hobbs; Cynthia J (C.J.) Doane; Motomi Mori; Michael K Axthelm; Michael K Axthelm; Deborah A Lewinsohn; Janko Nikolich-Zugich
Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6739-45.
2010: Scott G Hansen; Colin J Powers; Rebecca Richards; Abigail B Ventura; Julia C Ford; Don Siess; Michael K Axthelm; Jay A Nelson; Michael A Jarvis; Louis J Picker; Klaus J Frueh
Evasion of CD8+ T cells is critical for superinfection by cytomegalovirus.
Science (New York, N.Y.) 2010;328(5974):102-6.
2010: Anne M Wertheimer; Jennifer L Uhrlaub; Alec Hirsch; Guruprasad Medigeshi; Jerald Sprague; Alfred Legasse; Jennifer Wilk; Clayton A Wiley; Peter Didier; Robert B Tesh; Kristy Murray; Michael K Axthelm; Scott W Wong; Janko Nikolich-Žugich
Immune response to the West Nile virus in aged non-human primates.
PloS one 2010;5(12):e15514.
2009: B U Orzechowska; M Manoharan; J Sprague; Ryan D Estep; Michael K Axthelm; Scott W Wong
Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD).
Journal of medical primatology 2009;38 Suppl 1():2-7.
2009: Afam Okoye; Haesun J Park; Mukta Rohankhedkar; Lia Coyne-Johnson; Richard Lum; Joshua M Walker; Shannon Planer; Alfred W Legasse; Andrew W Sylwester; Michael Piatak; Jeffrey D Lifson; Donald L Sodora; Francios VILLINGER; Michael K Axthelm; Joern E Schmitz; Louis J Picker
Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.
The Journal of experimental medicine 2009;206(7):1575-88.
2009: Scott G Hansen; Cassandra Vieville; Nathan Whizin; Lia Coyne-Johnson; Don C Siess; Derek D Drummond; Alfred W Legasse; Michael K Axthelm; Kelli Oswald; Charles M Trubey; Michael Piatak; Jeffrey D Lifson; Jay A Nelson; Michael A Jarvis; Louis J Picker
Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge.
Nature medicine 2009;15(3):293-9.
2009: Miles J Novy; Lynn Duffy; Michael K Axthelm; Drew W Sadowsky; Steven S Witkin; Michael G Gravett; Gail H Cassell; Kenneth B Waites
Ureaplasma parvum or Mycoplasma hominis as sole pathogens cause chorioamnionitis, preterm delivery, and fetal pneumonia in rhesus macaques.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(1):56-70.
2008: Beata U Orzechowska; Michael F Powers; Jerald Sprague; He Li; Bonnie Yen; Robert Searles; Michael K Axthelm; Scott W Wong
Rhesus macaque rhadinovirus-associated non-Hodgkin lymphoma: animal model for KSHV-associated malignancies.
Blood 2008;112(10):4227-34.
2008: Xin Dang; Christian Wüthrich; Michael K Axthelm; Igor J Koralnik
Productive simian virus 40 infection of neurons in immunosuppressed Rhesus monkeys.
Journal of neuropathology and experimental neurology 2008;67(8):784-92.
2008: Shannon M Murray; Louis J Picker; Michael K Axthelm; Kelly Hudkins; Charles E Alpers; Maxine L Linial
Replication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections.
Journal of virology 2008;82(12):5981-5.
2008: David A Price; Arlene D Bitmansour; John B Edgar; Joshua M Walker; Michael K Axthelm; Daniel C Douek; Louis J Picker
Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):269-80.
2007: Luka Cicin-Sain; Ilhem Messaoudi; Byung S Park; Noreen Currier; Shannon Planer; Miranda Fischer; Shane Tackitt; Dragana Nikolich-Zugich; Alfred Legasse; Michael K Axthelm; Louis J Picker; Motomi Mori; Janko Nikolich-Zugich
Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19960-5.
2007: Michael G Gravett; Kristina M Adams; Drew W Sadowsky; Alexandra R Grosvenor; Steven S Witkin; Michael K Axthelm; Miles J Novy
Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model.
American journal of obstetrics and gynecology 2007;197(5):518.e1-8.
2007: Afam Okoye; Martin Meier-Schellersheim; Jason M Brenchley; Shoko I Hagen; Joshua M Walker; Mukta Rohankhedkar; Richard Lum; John B Edgar; Shannon Planer; Alfred Legasse; Andrew W Sylwester; Michael Piatak; Jeffrey D Lifson; Vernon C Maino; Donald L Sodora; Daniel C Douek; Michael K Axthelm; Zvi Grossman; Louis J Picker
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
The Journal of experimental medicine 2007;204(9):2171-85.
2006: Andrew D Weinberg; Colin Thalhofer; Nick Morris; Joshua M Walker; Donald Seiss; Scott W Wong; Michael K Axthelm; Louis J Picker; Walter J Urba
Anti-OX40 (CD134) administration to nonhuman primates: immunostimulatory effects and toxicokinetic study.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(6):575-85.
2006: David H Margolin; Erika H Saunders; Benjamin Bronfin; Nicole de Rosa; Michael K Axthelm; Olga Goloubeva; Sara Eapen; Rebecca Gelman; Norman L Letvin
Germinal center function in the spleen during simian HIV infection in rhesus monkeys.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1108-19.
2006: Louis J Picker; Edward F Reed-Inderbitzin; Shoko I Hagen; John B Edgar; Scott G Hansen; Alfred Legasse; Shannon Planer; Michael Piatak; Jeffrey D Lifson; Vernon C Maino; Michael K Axthelm; Francios VILLINGER
IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates.
The Journal of clinical investigation 2006;116(6):1514-24.
2006: Shannon M Murray; Louis J Picker; Michael K Axthelm; Maxine L Linial
Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression.
Journal of virology 2006;80(2):663-70.
2005: Xin Dang; Michael K Axthelm; Norman L Letvin; Igor J Koralnik
Rearrangement of simian virus 40 regulatory region is not required for induction of progressive multifocal leukoencephalopathy in immunosuppressed rhesus monkeys.
Journal of virology 2005;79(3):1361-6.
2004: Louis J Picker; Shoko I Hagen; Richard Lum; Edward F Reed-Inderbitzin; Lyn M Daly; Andrew W Sylwester; Joshua M Walker; Don C Siess; Michael Piatak; Chenxi Wang; David Allison; Vernon C Maino; Jeffrey D Lifson; Toshiaki Kodama; Michael K Axthelm
Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.
The Journal of experimental medicine 2004;200(10):1299-314.
2004: Michael K Axthelm; Igor J Koralnik; Xin Dang; Christian Wüthrich; Daniela Rohne; Isaac E Stillman; Norman L Letvin
Meningoencephalitis and demyelination are pathologic manifestations of primary polyomavirus infection in immunosuppressed rhesus monkeys.
Journal of neuropathology and experimental neurology 2004;63(7):750-8.
2004: Kent Hermsmeyer; Rajesh G Mishra; Dusan Pavcnik; Barry T Uchida; Michael K Axthelm; Frank Z Stanczyk; Kenneth A Burry; D Roger Illingworth; Carlos Juan; Frank J Nordt
Prevention of coronary hyperreactivity in preatherogenic menopausal rhesus monkeys by transdermal progesterone.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(5):955-61.
2004: Byeongwoon Song; Mark Cayabyab; Ngoc Phan; Liping Wang; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease.
Virology 2004;322(1):168-81.
2004: Mark Cayabyab; Daniela Rohne; Georgios Pollakis; Claudia Mische; Tsehaynesh Messele; Almaz Abebe; Bijan Etemad-Moghadam; Peter Yang; Scott Henson; Michael K Axthelm; Jaap Goudsmit; Norman L Letvin; Joseph Sodroski
Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate.
AIDS research and human retroviruses 2004;20(1):27-40.
2003: Sallie R Permar; Sherry A Klumpp; Keith G Mansfield; Woong-Ki Kim; Darci A Gorgone; Michelle A Lifton; Kenneth C Williams; Joern schmitz; Keith A Reimann; Michael K Axthelm; Fernando P Polack; Diane E Griffin; Norman L Letvin
Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys.
Journal of virology 2003;77(7):4396-400.
2003: Ryan D Estep; Michael K Axthelm; Scott W Wong
A G protein-coupled receptor encoded by rhesus rhadinovirus is similar to ORF74 of Kaposi's sarcoma-associated herpesvirus.
Journal of virology 2003;77(3):1738-46.
2002: Bijan Etemad-Moghadam; Daniela Rhone; Tavis Steenbeke; Ying Sun; Judith Manola; Rebecca Gelman; John W Fanton; Paul Racz; Klara Tenner-Racz; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus.
Vaccine 2002;20(15):1934-7.
2002: David H Margolin; Erika F Helmuth Saunders; Benjamin Bronfin; Nicole de Rosa; Michael K Axthelm; Xavier Alvarez; Norman L Letvin
High frequency of virus-specific B lymphocytes in germinal centers of simian-human immunodeficiency virus-infected rhesus monkeys.
Journal of virology 2002;76(8):3965-73.
2002: Christine J Pitcher; Shoko I Hagen; Joshua M Walker; Richard Lum; Bridget L Mitchell; Vernon C Maino; Michael K Axthelm; Louis J Picker
Development and homeostasis of T cell memory in rhesus macaque.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):29-43.
2001: A E Macias; Scott W Wong; Drew W Sadowsky; Craig Marc Luetjens; Michael K Axthelm; Michael G Gravett; George J Haluska; Miles J Novy
Maternal or fetal origin of rhesus monkey (Macaca mulatta) amniotic fluid leukocytes can be identified by polymerase chain reaction using the zinc finger Y gene.
American journal of primatology 2001;55(3):159-70.
2001: Sybille Muller; David H Margolin; G Min; Dingyuan Lou; PL Nara; Michael K Axthelm; Heinz Kohler
Stimulation of antiviral antibody response in SHIV-IIIB-infected macaques.
Scandinavian journal of immunology 2001;54(4):383-95.
2001: Bijan Etemad-Moghadam; D Rhone; Tavis Steenbeke; Ying Sun; Judith Manola; Rebecca Gelman; John W Fanton; Paul Racz; Klara Tenner-Racz; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus.
Journal of virology 2001;75(12):5646-55.
2001: Norman L Letvin; Suzanne Robinson; Daniela Rohne; Michael K Axthelm; John W Fanton; M Bilska; TJ Palker; Hua-Xin Liao; Barton F Haynes; David C Montefiori
Vaccine-elicited V3 loop-specific antibodies in rhesus monkeys and control of a simian-human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate envelope.
Journal of virology 2001;75(9):4165-75.
2000: Biao Li; Michael K Axthelm; Curtis A Machida
Simian retrovirus serogroup 5: partial gag-prt sequence and viral RNA distribution in an infected rhesus macaque.
Virus genes 2000;21(3):241-8.
2000: Brigitte E Beer; Elizabeth Bailes; G Dapolito; BJ Campbell; Robert M Goeken; Michael K Axthelm; P D Markham; J Bernard; D Zagury; G Franchini; Paul M Sharp; Vanessa M Hirsch
Patterns of genomic sequence diversity among their simian immunodeficiency viruses suggest that L'Hoest monkeys (Cercopithecus lhoesti) are a natural lentivirus reservoir.
Journal of virology 2000;74(8):3892-8.
1999: Scott W Wong; EP Bergquam; R M Swanson; F W Lee; SM Shiigi; Nancy Avery; John W Fanton; Michael K Axthelm
Induction of B cell hyperplasia in simian immunodeficiency virus-infected rhesus macaques with the simian homologue of Kaposi's sarcoma-associated herpesvirus.
The Journal of experimental medicine 1999;190(6):827-40.
1999: EP Bergquam; Nancy Avery; SM Shiigi; Michael K Axthelm; Scott W Wong
Rhesus rhadinovirus establishes a latent infection in B lymphocytes in vivo.
Journal of virology 1999;73(9):7874-6.
1999: Gail H Marracci; Nancy Avery; SM Shiigi; G Couch; H Palmer; KY Pilcher; H Nichols; Lesley Marie Hallick; Michael K Axthelm; Curtis A Machida
Molecular cloning and cell-specific growth characterization of polymorphic variants of type D serogroup 2 simian retroviruses.
Virology 1999;261(1):43-58.
1999: G G Eaton; J M Worlein; S T Kelley; S Vijayaraghavan; David L Hess; Michael K Axthelm; Cynthia L Bethea
Self-injurious behavior is decreased by cyproterone acetate in adult male rhesus (Macaca mulatta).
Hormones and behavior 1999;35(2):195-203.
1999: Robert Searles; EP Bergquam; Michael K Axthelm; Scott W Wong
Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.
Journal of virology 1999;73(4):3040-53.
1999: Keith A Reimann; A Watson; P J Dailey; Wenyu Lin; Carol I Lord; Tavis Steenbeke; Robert A Parker; Michael K Axthelm; GB Karlsson
Viral burden and disease progression in rhesus monkeys infected with chimeric simian-human immunodeficiency viruses.
Virology 1999;256(1):15-21.
1999: Vanessa M Hirsch; BJ Campbell; Elizabeth Bailes; Robert M Goeken; C Brown; WR Elkins; Michael K Axthelm; M Murphey-Corb; Paul M Sharp
Characterization of a novel simian immunodeficiency virus (SIV) from L'Hoest monkeys (Cercopithecus l'hoesti): implications for the origins of SIVmnd and other primate lentiviruses.
Journal of virology 1999;73(2):1036-45.
1999: Mark Cayabyab; GB Karlsson; Bijan Etemad-Moghadam; W Hofmann; Tavis Steenbeke; M Halloran; John W Fanton; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2).
Journal of virology 1999;73(2):976-84.
1998: Michael K Axthelm; S Krakowka
Experimental old dog encephalitis (ODE) in a gnotobiotic dog.
Veterinary pathology 1998;35(6):527-34.
1998: GB Karlsson; M Halloran; D Schenten; Juliette Lee; Paul Racz; Klara Tenner-Racz; Judith Manola; Rebecca Gelman; Bijan Etemad-Moghadam; E Desjardins; Richard Wyatt; Norma P Gerard; L Marcon; David H Margolin; John W Fanton; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.
The Journal of experimental medicine 1998;188(6):1159-71.
1998: Cynthia L Bethea; Michael G Gravett; Drew W Sadowsky; George J Haluska; Michael K Axthelm; Miles J Novy; M K Axethelm
Amniotic fluid prolactin is decreased by experimental intrauterine infection or interleukin-1beta infusion but not via prostaglandins in pregnant rhesus macaques.
Biology of reproduction 1998;58(6):1385-93.
1998: Richard D Minshall; F Z Stanczyk; K Miyagawa; Barry T Uchida; Michael K Axthelm; Miles J Novy; Kent Hermsmeyer
Ovarian steroid protection against coronary artery hyperreactivity in rhesus monkeys.
The Journal of clinical endocrinology and metabolism 1998;83(2):649-59.
1997: GB Karlsson; M Halloran; J Li; I W Park; R Gomila; Keith A Reimann; Michael K Axthelm; S A Iliff; Norman L Letvin; Joseph Sodroski
Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys.
Journal of virology 1997;71(6):4218-25.
1997: Kent Hermsmeyer; K Miyagawa; S T Kelley; Josef Rosch; Alistair Hall; Michael K Axthelm; B Greenberg
Reactivity-based coronary vasospasm independent of atherosclerosis in rhesus monkeys.
Journal of the American College of Cardiology 1997;29(3):671-80.
1996: M A Whitney; G Royle; Malcolm J Low; M A Kelly; Michael K Axthelm; Carol A Reifsteck; Susan B Olson; R E Braun; Michael C Heinrich; R Keaney Rathbun; Grover C Bagby; Markus Grompe
Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene.
Blood 1996;88(1):49-58.
1995: Wolfgang Baumgärtner; R W Boyce; S E Weisbrode; S Aldinger; Michael K Axthelm; Steven Krakowka
Histologic and immunocytochemical characterization of canine distemper-associated metaphyseal bone lesions in young dogs following experimental infection.
Veterinary pathology 1995;32(6):702-9.
1995: C L Endres; EP Bergquam; Michael K Axthelm; Scott W Wong
Suppression of simian immunodeficiency virus replication by human immunodeficiency virus type 1 trans-dominant negative rev mutants.
Journal of virology 1995;69(8):5164-6.
1995: C L Endres; EP Bergquam; Michael K Axthelm; Scott W Wong
Assessing genetic-based therapies for AIDS using the simian immunodeficiency virus.
Journal of medical primatology 1995;24(3):141-4.
1995: Wolfgang Baumgärtner; R W Boyce; Susanne Alldinger; Michael K Axthelm; S E Weisbrode; Steven Krakowka; K Gaedke
Metaphyseal bone lesions in young dogs with systemic canine distemper virus infection.
Veterinary microbiology 1995;44(2-4):201-9.
1995: Gail H Marracci; R D Kelley; K Y Pilcher; L Crabtree; SM Shiigi; Nancy Avery; G Leo; M C Webb; Lesley Marie Hallick; Michael K Axthelm
Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.
Journal of virology 1995;69(4):2621-8.
1994: K Y Pilcher; Nancy Avery; SM Shiigi; N Pangares; A Malley; Michael K Axthelm; Curtis A Machida
Polymerase chain reaction detection of type D simian retrovirus proviral DNA from infected macaques.
Journal of virological methods 1994;50(1-3):75-86.
1994: M Rene Malinow; Michael K Axthelm; M J Meredith; N A MacDonald; Barbara M Upson
Synthesis and transsulfuration of homocysteine in blood.
The Journal of laboratory and clinical medicine 1994;123(3):421-9.
1993: José V Torres; A Malley; B Banapour; David E Anderson; Michael K Axthelm; Murray B Gardner; E Benjamini
An epitope on the surface envelope glycoprotein (gp130) of simian immunodeficiency virus (SIVmac) involved in viral neutralization and T cell activation.
AIDS research and human retroviruses 1993;9(5):423-30.
1993: A Malley; N Pangares; S K Mayo; M Zeleny-Pooley; José V Torres; E Benjamin; Michael K Axthelm
Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques.
Journal of medical primatology 1993;22(2-3):80-5.
1993: José V Torres; David E Anderson; A Malley; B Banapour; Michael K Axthelm; E Benjamini; Murray B Gardner
SIV envelope glycoprotein epitopes recognized by antibodies from infected or vaccinated rhesus macaques.
Journal of medical primatology 1993;22(2-3):129-37.
1992: A Malley; José V Torres; E Benjamini; N Pangares; Michael K Axthelm
Characterization of T cell epitopes on the envelope glycoprotein of simian retrovirus 1 and 2 (SRV-1 and SRV-2) in several mouse strains.
Molecular immunology 1992;29(7-8):999-1004.
1992: S A Iliff-Sizemore; Michael K Axthelm; J L Edwards
Diagnostic exercise: sudden death in a rhesus macaque (Macaca mulatta).
Laboratory animal science 1992;42(2):202-3.
1991: A Malley; L Werner; E Benjamini; C Y Leung; José V Torres; N Pangares; SM Shiigi; Michael K Axthelm
Characterization of T- and B-cell epitopes of a simian retrovirus (SRV-2) envelope protein.
Journal of medical primatology 1991;20(4):177-81.
1990: Michael K Axthelm; SM Shiigi
Nonhuman primate models for acquired immunodeficiency syndrome.
Journal of medical primatology 1990;19(3-4):163-5.
1989: A Malley; SM Shiigi; E Benjamini; L Werner; C Y Leung; H S Kwang; Michael K Axthelm; Lesley Marie Hallick
Characterization of a synthetic envelope peptide of SRV-1 and SRV-2 virus that specifically binds rhesus anti-SRV-1 and anti-SRV-2 neutralizing antibodies.
Advances in experimental medicine and biology 1989;251():169-73.
1987: Steven Krakowka; L C Cork; J A Winkelstein; Michael K Axthelm
Establishment of central nervous system infection by canine distemper virus: breach of the blood-brain barrier and facilitation by antiviral antibody.
Veterinary immunology and immunopathology 1987;17(1-4):471-82.
1987: Michael K Axthelm; S Krakowka
Canine distemper virus-induced thrombocytopenia.
American journal of veterinary research 1987;48(8):1269-75.
1987: Steven Krakowka; Michael K Axthelm; J R Gorham
Effects of induced thrombocytopenia on viral invasion of the central nervous system in canine distemper virus infection.
Journal of comparative pathology 1987;97(4):441-50.
1987: S Krakowka; S S Ringler; M Lewis; R G Olsen; Michael K Axthelm
Immunosuppression by canine distemper virus: modulation of in vitro immunoglobulin synthesis, interleukin release and prostaglandin E2 production.
Veterinary immunology and immunopathology 1987;15(3):181-201.
1987: Michael K Axthelm; Steven Krakowka; J R Gorham
Canine distemper virus: in vivo virulence of in vitro-passaged persistent virus strains.
American journal of veterinary research 1987;48(2):227-34.
1987: G C Johnson; S Krakowka; Michael K Axthelm
Albumin leakage into cerebrospinal fluid of dogs lethally infected with R252 canine distemper virus.
Journal of neuroimmunology 1987;14(1):61-74.
1987: G C Johnson; S Krakowka; Michael K Axthelm
Prolonged viral antigen retention in the brain of a gnotobiotic dog experimentally infected with canine distemper virus.
Veterinary pathology 1987;24(1):87-9.
1987: Michael K Axthelm; S Krakowka
Canine distemper virus: the early blood-brain barrier lesion.
Acta neuropathologica 1987;75(1):27-33.
1986: M Oglesbee; D Jackwood; K Perrine; Michael K Axthelm; S Krakowka; J Rice
In vitro detection of canine distemper virus nucleic acid with a virus-specific cDNA probe by dot-blot and in situ hybridization.
Journal of virological methods 1986;14(3-4):195-211.
1986: J M Mastro; Michael K Axthelm; L E Mathes; S Krakowka; W Ladiges; R G Olsen
Repeated suppression of lymphocyte blastogenesis following vaccinations of CPV-immune dogs with modified-live CPV vaccines.
Veterinary microbiology 1986;12(3):201-11.
1986: Michael K Axthelm; S Krakowka
Immunocytochemical methods for demonstrating canine distemper virus antigen in aldehyde-fixed paraffin-embedded tissue.
Journal of virological methods 1986;13(3):215-29.
1984: A E Metzler; Steven Krakowka; Michael K Axthelm; J R Gorham
In vitro propagation of canine distemper virus: establishment of persistent infection in Vero cells.
American journal of veterinary research 1984;45(10):2211-5.
1982: S Krakowka; Michael K Axthelm; N J Austin
Effects of cerebrospinal fluid sample collection on frequency and onset of acute fatal canine distemper-associated encephalomyelitis.
American journal of veterinary research 1982;43(9):1678-80.
1982: S Krakowka; R G Olsen; Michael K Axthelm; J Rice; K Winters
Canine parvovirus infection potentiates canine distemper encephalitis attributable to modified live-virus vaccine.
Journal of the American Veterinary Medical Association 1982;180(2):137-9.
1981: Michael K Axthelm; H W Leipold; R M Phillips
Congenital internal hydrocephalus in Polled Hereford cattle.
Veterinary medicine, small animal clinician : VM, SAC 1981;76(4):567-70.
1981: Michael K Axthelm; H W Leipold; U M Jayasekara; R M Phillips
Congenital microhydranencephalus in cattle.
The Cornell veterinarian 1981;71(2):164-74.